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Pseudo-2d Mt Inversion Technique For Small-Frame Tem And Its Application In Advance Geological Prediction, Han Ziqiang, Wanma Longzhi, Li Xiangfeng, Yang Yongqiang, Zhu Xiaoming, Luo Chengxian, Tang Li Aug 2025

Pseudo-2d Mt Inversion Technique For Small-Frame Tem And Its Application In Advance Geological Prediction, Han Ziqiang, Wanma Longzhi, Li Xiangfeng, Yang Yongqiang, Zhu Xiaoming, Luo Chengxian, Tang Li

Coal Geology & Exploration

Objective To address the bottlenecks of low computational efficiency and impracticality of multi-dimensional inversion in the advance geological prediction based on the transient electromagnetic method (TEM), this study developed a pseudo-two-dimensional (2D) magnetotelluric (MT) inversion technique for small-frame TEM based on time-frequency transformation. Methods First, this study corroborated the significant similarity between the late-time apparent resistivity derived using small-frame TEM and the Cagniard apparent resistivity in the MT method under the parameters commonly used in advance geological prediction. Then, the optimal time-frequency transformation coefficient (CTF) was introduced to achieve a rapid conversion from the late-time apparent resistivity …


Embedding Internationalization At Home – What Do Irish Heis Need?, Nidhi Piplani-Kapur, Don O'Neill, Helen Murphy, Suzanne Denieffe Aug 2025

Embedding Internationalization At Home – What Do Irish Heis Need?, Nidhi Piplani-Kapur, Don O'Neill, Helen Murphy, Suzanne Denieffe

Journal of Comparative & International Higher Education

In Irish higher education, only four percent of learners have benefited from mobility opportunities. Whilst mobility continues to be accessible to a limited few, Irish higher education institutions (HEIs) increasingly realize the need to engage in 'Internationalization at home (IaH)' to provide international experiences to all learners. However, as evident from the literature review, IaH has been underdeveloped and understudied to date in the Irish context. Grounded in organizational and curriculum design and change management theories, this study critiques the development of IaH and suggests strategies to embed a culture of IaH in Irish HEIs. It adopts a constructivist-interpretivist methodology …


Innovating Higher Education - A Case Study Of Challenger Universities In Africa, Andrea Lane Aug 2025

Innovating Higher Education - A Case Study Of Challenger Universities In Africa, Andrea Lane

Journal of Comparative & International Higher Education

Sustainable Development Goal (SDG) 4 seeks to provide accessible and affordable higher education by 2030. While traditional universities in Africa evolve slowly to meet this goal, challenger universities are emerging to disrupt higher education. Examining the innovation practices of two of these institutions, this case study identifies four key practices: financial innovation, the Hub and Spoke model, competency-based online education, and the application of emerging technologies. Drawing on innovation management and higher education theories, the study draws new insights into how challenger universities address Africa’s unique challenges.


Cultivating Climate And Culture: New Jersey Principals' Use Of Sel In Pk-12 Schools, Michelle Papa Aug 2025

Cultivating Climate And Culture: New Jersey Principals' Use Of Sel In Pk-12 Schools, Michelle Papa

Theses and Dissertations

The purpose of this qualitative, intrinsic case study is to explore how PK-12 principals in New Jersey perceive their approaches to leadership through their own social and emotional learning (SEL). With growing demands placed on school leaders, the study examines how principals integrate the five SEL competencies (self-awareness, self- management, social awareness, relationship skills, and responsible decision-making) into their leadership practices to positively impact school climate and culture. Through semi- structured interviews and document analysis, ten principals revealed that SEL is not only essential for student and staff well-being but also central to their own leadership development. Findings indicate that …


Inaction As Nonformal Reaction: Rethinking Crime Perception In The Era Of Data Breaches, Irnasya Shafira Hadi Aug 2025

Inaction As Nonformal Reaction: Rethinking Crime Perception In The Era Of Data Breaches, Irnasya Shafira Hadi

Jurnal Kriminologi Indonesia

This study analyses the Indonesian public’s response to government data breaches and advocates for an expanded defintion of nonformal reactions to crime in the digital context. It argues that existing criminological frameworks, particularly Mustofa’s (2021) model—which views nonformal reactions as active and confrontational behaviours such as demonstrations or vigilantism—should also acknowledge inaction, apathy, and emotional disengagement as valid public reactions. This paper employs a conceptual-qualitative approach, combining an interdisciplinary literature review, interpretive policy analysis of the Personal Data Protection Law, and triangulation with digital behaviour data to develop its analysis. This paper reframes apathy as a significant criminological indicator of …


Intersectionality In The Maze Of Oppression: A Feminist Criminology Analysis Of Systematic Vulnerability And Exploitation Of Indonesian Women Trafficked To Cambodia, Reza Anugrah, Lifiana Alanisya Mutaharina Aug 2025

Intersectionality In The Maze Of Oppression: A Feminist Criminology Analysis Of Systematic Vulnerability And Exploitation Of Indonesian Women Trafficked To Cambodia, Reza Anugrah, Lifiana Alanisya Mutaharina

Jurnal Kriminologi Indonesia

This study explores the vulnerability of Indonesian women to the crime of human trafficking in Cambodia, analyzing its structural and patriarchal roots. Employing a qualitative methodology through literature review, the paper delineates how socio-economic disparities and limited employment opportunities in Indonesia drive women toward illegal job offers that ultimately result in exploitation. Human trafficking syndicates exploit traditional gender constructs and manipulate identities to entrap victims, even involving women as alleged perpetrators. Criminological and legal analyses reveal a shift toward more complex forms of transnational crime, exacerbated by the use of digital technology. Although the Law of the Republic of Indonesia …


Fracturing Evolution Mechanisms Of Eroded Coals Under The Temperature Effect Of The Co2-H2O System, Lin Baiquan, Shi Yu, Liu Ting, Shen Yang, Huang Tao Aug 2025

Fracturing Evolution Mechanisms Of Eroded Coals Under The Temperature Effect Of The Co2-H2O System, Lin Baiquan, Shi Yu, Liu Ting, Shen Yang, Huang Tao

Coal Geology & Exploration

Background Injecting hot flue gas produced and discharged by gas-fired power plants into deep coal seams where gas is difficult to extract enjoys dual benefits: gas production growth and geologic CO2 sequestration. However, there is an urgent need to determine the impact of the heat-carrying property of hot flue gas on the stability of coal reservoirs. To address this issue, the key is to clarify the fracturing evolution mechanisms of eroded coals under the temperature effect of the CO2-H2O system.Methods Using the independently built platform of CO2-H2O-coal interactions that consider …


Impacts Of Co2/Ch4/N2 Adsorption/Desorption On The Macromolecular Structure Of Anthracite: Insights From In Situ Raman Spectroscopy, Wang Tian, Pan Jienan, Li Meng, Wang Kai, Tang Zhuyun, Cheng Nannan, Hou Quanlin Aug 2025

Impacts Of Co2/Ch4/N2 Adsorption/Desorption On The Macromolecular Structure Of Anthracite: Insights From In Situ Raman Spectroscopy, Wang Tian, Pan Jienan, Li Meng, Wang Kai, Tang Zhuyun, Cheng Nannan, Hou Quanlin

Coal Geology & Exploration

Objective and Methods The adsorption/desorption of coalbed methane (CBM) not only induces the macroscopic deformations of coals but also significantly alters their macromolecular structures, with different gases exhibiting greatly varying mechanisms and influence degrees. Utilizing an independently developed in situ laser Raman spectroscopy system, this study revealed the differential structural responses and mechanisms of anthracite under CO2, CH4, and N2 injection. Results and Conclusion Experimental results indicate that gas injection led to notable blue shifts in the D4, D, D3, and G peaks characterizing the microcrystalline structures of coals. In contrast, …


Advances In Research On Geological Evaluation Of Compressed Air Energy Storage In Underground Gas Storage Facilities, Jiang Wen, Huang Leqing, Zhang Songhang, Ma Huiying Aug 2025

Advances In Research On Geological Evaluation Of Compressed Air Energy Storage In Underground Gas Storage Facilities, Jiang Wen, Huang Leqing, Zhang Songhang, Ma Huiying

Coal Geology & Exploration

Background Against the backdrop of achieving peak carbon dioxide emissions and carbon neutrality globally, renewable energy has developed rapidly and is gradually changing the world's energy mix. However, the intermittent and fluctuating nature of photovoltaic and wind power energy is prone to cause grid frequency fluctuations and reduced power supply reliability. Compressed air energy storage (CAES) technology has emerged as the key to the stable operation of the green power grid thanks to its large capacity and low cost.Methods Based on a systematic review of domestic and international literature in recent years, this study organizes the current theoretical and …


Log-Based Identification Of Sedimentary Facies In Coal Measures In The Southern Wuxiang Block, Shanxi Province, China, Jin Yi, Tian Yunqing, Song Huibo, Hu Bin, Yu Zhenfeng Aug 2025

Log-Based Identification Of Sedimentary Facies In Coal Measures In The Southern Wuxiang Block, Shanxi Province, China, Jin Yi, Tian Yunqing, Song Huibo, Hu Bin, Yu Zhenfeng

Coal Geology & Exploration

Objective The Carboniferous and Permian coal-bearing strata in the southern Wuxiang block, Qinshui Basin, Shanxi Province, China contain abundant coalbed methane (CBM) resources. To develop intelligent discrimination technology for CBM exploration in this block, it is necessary to establish lithology discrimination criteria based on log data, reveal the response relationships between logging and sedimentary facies, and determine sedimentary patterns. Methods Using a comprehensive analysis of lithologies, sedimentary facies, and logging facies, this study systematically investigated the distributions of logging and sedimentary facies in the Shanxi and Taiyuan formations—the primary coal-bearing strata in the southern Wuxiang block. By comprehensively analyzing the …


Spatial Distribution Of Coalbed Methane Migration Pathways And Selection Of Optimal Target Areas For Coalbed Methane Extraction For Abandoned Mines, Liu Qinjie, Yang Youxing, Wu Benniu, Duan Minke, Deng Zhuoyue, Guo Chenye, Sun Qiang Aug 2025

Spatial Distribution Of Coalbed Methane Migration Pathways And Selection Of Optimal Target Areas For Coalbed Methane Extraction For Abandoned Mines, Liu Qinjie, Yang Youxing, Wu Benniu, Duan Minke, Deng Zhuoyue, Guo Chenye, Sun Qiang

Coal Geology & Exploration

Objective and Methods The spatial distribution and long-term evolution of effective migration pathways determine the migration pathways of residual coalbed methane (CBM) in abandoned mines. Furthermore, they provide an important basis for selecting the optimal target areas for CBM extraction drilling in abandoned mines and maximizing extraction efficiency. This study investigated the first mining area at the first horizontal elevation of the Songzao Coal Mine in Chongqing. Using a comprehensive approach that integrated theoretical analysis, numerical simulations, and physical simulation experiments using similar materials, this study systematically examined the distribution patterns of effective CBM migration pathways in abandoned mines under …


Geochemical Characteristics And Genesis Of Element Enrichment Of Niobium-Rich-Rare Earth Metal Layer In Longtan Formation Of Zhina Coalfield, Ding Yunlong, Wang Fangfa, Li Bi, Tang Lifang, Yang Yi, Li Shangyuan, Wang Xiaofang, Zou Yinhong, Wang Yang Aug 2025

Geochemical Characteristics And Genesis Of Element Enrichment Of Niobium-Rich-Rare Earth Metal Layer In Longtan Formation Of Zhina Coalfield, Ding Yunlong, Wang Fangfa, Li Bi, Tang Lifang, Yang Yi, Li Shangyuan, Wang Xiaofang, Zou Yinhong, Wang Yang

Coal Geology & Exploration

Background With the increasing demand for strategic metals and the gradual depletion of traditional metal deposit resources, coal and coal-bearing rock series are considered to be potential sources of rare metals, and coal series associated has become one of the main directions of current mineral exploration. A set of coal measure strata rich in niobium (Nb) and rare earth elements (REE) has been found in Zhina coalfield, western Guizhou and the contents of Nb and REE are as high as 334.89 μg/g and 1014.51 μg/g, respectively. This discovery is of great significance to the theoretical study of coal measure metal …


Macroscopic Failure Characteristics And Seepage Pattern Of Damaged Goaf-Side Coal Pillars Under Confined Water Accumulation, Liu Weitao, Chen Dongqi, Liu Yuben, Du Yanhui, Zhao Jiyuan Aug 2025

Macroscopic Failure Characteristics And Seepage Pattern Of Damaged Goaf-Side Coal Pillars Under Confined Water Accumulation, Liu Weitao, Chen Dongqi, Liu Yuben, Du Yanhui, Zhao Jiyuan

Coal Geology & Exploration

Background The method of supporting roadways using small coal pillars has been widely applied in China. As a result, the stability of goaf-side coal pillars affects mining safety. Resulting from multiple disturbance effects, coal pillars tend to contain various types of damage fractures. The confined water environment in goaves with water accumulation might cause the instability failure of damaged goaf-side coal pillars. Methods To investigate the impacts of the damage fracture structure on coal stability, this study introduced the concept of relatively stable initial damage fractures. Based on the theory of damage mechanics, this study constructed hydro-mechanical-damage (HMD) coupling models …


3d Advanced Geological Prediction Based On Reflected Seismic Waves And Its Application Effects, Cai Sheng Aug 2025

3d Advanced Geological Prediction Based On Reflected Seismic Waves And Its Application Effects, Cai Sheng

Coal Geology & Exploration

Objective For the advance geological prediction of tunnels based on reflected seismic waves, the traditional 2D observation method tends to cause spatial positioning deviations of anomalies. To overcome this limitation, this study developed a 3D seismic wave-based advance geological prediction method according to the actual geometries of tunnels. Methods Using the technical path consisting of theoretical analysis, numerical simulation, and engineering verification, this study solved key technical challenges including 3D wavefield reconstruction, spatial modeling, and migration imaging in the 3D detection system. Based on the principle of geometric seismology, this study demonstrated the enhancement effects of 3D observation on the …


A Time Series Forecasting Model Integrating Spatial Features For Inter-Borehole Resistivity And Its Application, Wang Jianghong, Liu Shuo, Wang Gang, Xue Wuqiang, Li Bofan Aug 2025

A Time Series Forecasting Model Integrating Spatial Features For Inter-Borehole Resistivity And Its Application, Wang Jianghong, Liu Shuo, Wang Gang, Xue Wuqiang, Li Bofan

Coal Geology & Exploration

Background Mine resistivity prediction serves as a core technique for water hazards monitoring in coal mines. However, due to sparse monitoring points and insufficient spatial resolution, conventional prediction approaches fail to capture dynamic resistivity variations under complex geological conditions.Objective and Methods To address this challenge, this study developed a deep learning-based time series forecasting model integrating spatial features for inter-borehole resistivity. Using a prediction framework constructed based on long short-term memory (LSTM) and critical spatial monitoring points selected through Pearson correlation analysis, this model (also referred to as the LSTM model) enabled high-precision prediction of resistivity in unknown areas. …


Hybrid Differentiator-Based Method For Estimating The Drilling Speed Of A Vehicle-Mounted Drilling Rig During Surface Drilling For Mine Rescue, Wang Yunfei, Zhao Jiyun, Hu Yongjie, Zhang Zongyang, Pan Xiaochen Aug 2025

Hybrid Differentiator-Based Method For Estimating The Drilling Speed Of A Vehicle-Mounted Drilling Rig During Surface Drilling For Mine Rescue, Wang Yunfei, Zhao Jiyun, Hu Yongjie, Zhang Zongyang, Pan Xiaochen

Coal Geology & Exploration

Background Vehicle-mounted drilling rigs (VMDRs), key devices in surface drilling for mine rescue, directly connect the ground and underground disaster-hit areas through vertical drilling, thereby creating rescue channels for trapped people. In this case, the drilling speed of VMDRs serves as an important indicator for evaluating surface drilling operations. However, directly determining the drilling speed is challenging due to the limitations of position sensors. Methods This study developed an estimation method based on a new hybrid differentiator (NHD), allowing the drilling speed to be calculated using measurable displacement signals. First, a continuous switching function was devised, and its convergence characteristics …


Parameter Characteristics And Rock-Breaking Mechanisms Of Horizontal Drilling Of Underground Collapsed Bodies In Coal Mines, Yao Ningping, Dou Xuqian, Han Zhaoyang, Zhang Guohua, Sun Yuchen, Li Hao, Wang Li Aug 2025

Parameter Characteristics And Rock-Breaking Mechanisms Of Horizontal Drilling Of Underground Collapsed Bodies In Coal Mines, Yao Ningping, Dou Xuqian, Han Zhaoyang, Zhang Guohua, Sun Yuchen, Li Hao, Wang Li

Coal Geology & Exploration

Objective With continuously increasing coal mining depth, the risks of hazards such as roof collapse and personnel entrapment caused by high in situ stress and mining-induced pressure have significantly intensified. Drilling emerges as a key means of rapidly establishing rescue passageways. However, the drilling process tends to face multiple challenges, including complex geological structures, unstable collapsed bodies, and low drilling efficiency. Methods This study aims to reveal the rock-breaking mechanisms during the drilling of collapsed bodies, optimize drilling parameters to ensure reliable borehole formation, and achieve efficient drilling of collapsed bodies. To this end, this study developed a large-scale experimental …


Parent Roles Supporting Curriculum And Instruction With Virtual Learning During The Covid-19 Pandemic, Keli Louise Amprey Aug 2025

Parent Roles Supporting Curriculum And Instruction With Virtual Learning During The Covid-19 Pandemic, Keli Louise Amprey

Walden Dissertations and Doctoral Studies

The COVID-19 pandemic created an educational crisis when schools across the United States closed abruptly, requiring parents to assume new roles as facilitators of online learning without adequate preparation. Guided by Bandura’s social learning theory, the purpose of this retrospective basic qualitative study was to investigate parents’ perceptions of their roles as instructional and curriculum facilitators for elementary-level students during COVID-19 distance learning. Research questions examined how parents described their roles as online instructional facilitators, what challenges they faced in supporting curriculum and instruction virtually, and what types of support they needed to succeed in their new educational roles during …


The Association Between Malnutrition And Gingivitis Among Residents In St. Louis, Missouri, Alyssa Detrick Aug 2025

The Association Between Malnutrition And Gingivitis Among Residents In St. Louis, Missouri, Alyssa Detrick

Walden Dissertations and Doctoral Studies

Malnutrition and gingivitis are common diagnoses in primary medical and dental care. The purpose of this quantitative study was to understand the association between malnutrition and gingivitis among residents in St. Louis, Missouri. The study was based on the social ecological model (SEM). The cross-sectional design involved secondary data (N = 2,553) from a Federally Qualified Health Center in St. Louis, Missouri that included de-identified patient demographic and diagnosis information of St. Louis City residents with a medical and dental visit in 2024. This study examined the relationship between malnutrition and gingivitis while controlling for ethnicity, preferred language, race, and …


The Free Press Vol. 57, Issue 1, 08-25-2025, Julz Levesque, Caraline Squires Aug 2025

The Free Press Vol. 57, Issue 1, 08-25-2025, Julz Levesque, Caraline Squires

Free Press, The

Welcome Letter from the Dean--Learning Commons Welcome Letter--SEAB Welcome--University Health & Counseling--Public Safety & Journal of Scandal--Welcome from Editors=in=Chief


Epidemiological-Based Study Of Sars-Cov-2 In Faisalabad, Sana Ullah, Muhammad Waseem Khan, Qurat-Ul- Ain, Khushbu Farva, Niaz Muhammad Khan, Hayat Ullah Aug 2025

Epidemiological-Based Study Of Sars-Cov-2 In Faisalabad, Sana Ullah, Muhammad Waseem Khan, Qurat-Ul- Ain, Khushbu Farva, Niaz Muhammad Khan, Hayat Ullah

Biological Engineering Student Research

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raced around the world across different populations; there needs to be a consolidated effort to understand the divergence of the epidemiology of SARS-CoV-2. Population-based epidemiological characteristics studies measure the extent of SARS-CoV-2 infection in a country. The current research study was designed to report epidemiological data from Pakistan. For this purpose, 246 SARS-CoV-2-infected patients were included in the study. For SARS-CoV-2 confirmation, viral samples were collected from all the study participants; SARS-CoV-2 infection was confirmed by viral nucleic acid detection using a nucleic acid detection kit. After SARS-CoV-2 confirmation, all the study participants …


Spatially Resolved Kinematics Of Slacs Lens Galaxies. I. Data And Kinematic Classification, Shawn Knabel, Tommaso Treu, Michele Cappellari, Anowar J. Shajib, Chih-Fan Chen, Simon Birrer, Vardha N. Bennert Aug 2025

Spatially Resolved Kinematics Of Slacs Lens Galaxies. I. Data And Kinematic Classification, Shawn Knabel, Tommaso Treu, Michele Cappellari, Anowar J. Shajib, Chih-Fan Chen, Simon Birrer, Vardha N. Bennert

Physics

We obtain spatially resolved kinematics with the Keck Cosmic Web Imager (KCWI) integral-field spectrograph for a sample of 14 massive (11 < log₁₀(M₍★₎/M☉) < 12) lensing early-type galaxies at z ∼ 0.15–0.35 from the Sloan Lens ACS (SLACS) Survey. We integrate kinematic maps within the galaxy effective radius and examine the rotational and dispersion velocities, showing that 11/14 can be classified as slow rotators. The data set is unprecedented for galaxy-scale strong lenses in terms of signal-to-noise ratio (S/N), sampling, and calibration, vastly superseding previous studies. We find the primary contributions to systematic uncertainties to be the stellar template library and wavelength range of the spectral fit. Systematics …


Flash Communication: Visible-Light-Driven, Cobalt-Mediated Selective C–H Arylation Of 2,2′-Bipyridine, Xi Chen, Eric R. Allen, Mckenzie L. Stack, Zachary M. Garozzo, Dian Wang Aug 2025

Flash Communication: Visible-Light-Driven, Cobalt-Mediated Selective C–H Arylation Of 2,2′-Bipyridine, Xi Chen, Eric R. Allen, Mckenzie L. Stack, Zachary M. Garozzo, Dian Wang

Chemistry Faculty Research and Publications

Herein, we report a visible-light-driven, cobalt-mediated, highly selective C–H arylation method to afford aryl-2,2′-bipyridine, a widely used class of ancillary ligands in transition metal catalysis. This arylation reaction exhibits good-to-excellent C6 selectivity for a variety of aryl groups, allowing for isolation of the 6-isomer in its pure form. Mechanistic studies provided evidence for the generation of an aryl radical by the joint action of [Co(bpy)3] species and visible light, enabling arylation under mild conditions. Compared to previous work, this method employs cost-effective reagents and provides one-step, direct access from 2,2′-bipyridine to a broad range of electronically varied 6-aryl-2,2′-bipyridine …


“Me Dancing”: An Intrinsic Case Study Of Primary School Boys’ Understandings Of Movement And Dance Through Their Drawings, Rosemary G. Bennett Ms, Jane Southcott Aug 2025

“Me Dancing”: An Intrinsic Case Study Of Primary School Boys’ Understandings Of Movement And Dance Through Their Drawings, Rosemary G. Bennett Ms, Jane Southcott

The Qualitative Report

In this research we explore the place of creative embodiment through movement and dance from the understandings of a group of 8-10-year-old elementary school boys. Children can be asked to speak or write about their movement experiences, but for younger cohorts it may easier for them to reveal their ideas via their own drawings. In this qualitative study using drawings as a research method, two classes (a total of 31) of Year 3-4 boys in a suburban elementary school in Melbourne, Australia were asked to produce a drawing of “me dancing” in an empty frame. Each child was then asked …


Analytical Characterization Of Artemisinin And Its Derivatives Using High Performance Liquid Chromatography, Electrochemistry Reduction, And Fluorescence, Faraja Ombwayo Aug 2025

Analytical Characterization Of Artemisinin And Its Derivatives Using High Performance Liquid Chromatography, Electrochemistry Reduction, And Fluorescence, Faraja Ombwayo

Theses and Dissertations

Artemisinin and derivatives were subjected to 37°C and room temperature conditions. When HPLC-UV analysis of both conditions was performed, there were differences in both conditions which suggested that artemisinin and derivatives degrade at 37°C. When artemisinin was electrochemically reduced, new peaks were generated and LC-MS analysis of the reduced artemisinin indicated that either new molecules or molecular reorganization was formed. These electrochemical reduction molecules (products) were deemed analogous to the artemisinin reduction occurring in-vivo after oral administration. Fluorescence analysis of artemisinin and derivatives were performed in the presence of dipyridamole. Dipyridamole intensity was observed to decrease when artemisinin or its …


Probing The Effect Of Peg-Dna Interactions And Buffer Viscosity On Tethered Dna In Shear Flow, Fatema Tuz Zohra, Huda Al-Zuhairi, Jefferson Reinoza, Hyeongjun Kim, Andreas Hanke Aug 2025

Probing The Effect Of Peg-Dna Interactions And Buffer Viscosity On Tethered Dna In Shear Flow, Fatema Tuz Zohra, Huda Al-Zuhairi, Jefferson Reinoza, Hyeongjun Kim, Andreas Hanke

Mechanical Engineering Faculty Publications

DNA flow-stretching is a widely employed, powerful technique for investigating the mechanisms of DNA-binding proteins involved in compacting and organizing chromosomal DNA. We combine single-molecule DNA flow-stretching experiments with Brownian dynamics simulations to study the effect of the crowding agent polyethylene glycol (PEG) in these experiments. PEG interacts with DNA by an excluded volume effect, resulting in compaction of single, free DNA molecules in PEG solutions. In addition, PEG increases the viscosity of the buffer solution. By stretching surface-tethered bacteriophage lambda DNA in a flow cell and tracking the positions of a quantum dot labeled at the free DNA end …


An Ehealth Delivery Alternative For Cancer Genetic Testing For Hereditary Predisposition In Patients With Metastatic Cancers: Protocol For A Randomized Trial, Kimberley T. Lee, Briana Mcleod, Brian Egleston, Sarah Brown, Sarah Howe, Dominique Fetzer, Lauren Gutstein, Cara Cacioppo, Dana Clark, Susan M. Domchek, Jessica Ebrahimzadeh, Dana Falcone, Demetrios Ofidis, Hannah Griffin, Rajia Mim, Santina Hernandez, Linda Fleisher, Kelsey Karpink, Enida Selmani, Aysha Tahsin, Lynne Wagner, Michelle Weinberg, Kuang-Yi Wen, Elisabeth Wood, Angela R. Bradbury Aug 2025

An Ehealth Delivery Alternative For Cancer Genetic Testing For Hereditary Predisposition In Patients With Metastatic Cancers: Protocol For A Randomized Trial, Kimberley T. Lee, Briana Mcleod, Brian Egleston, Sarah Brown, Sarah Howe, Dominique Fetzer, Lauren Gutstein, Cara Cacioppo, Dana Clark, Susan M. Domchek, Jessica Ebrahimzadeh, Dana Falcone, Demetrios Ofidis, Hannah Griffin, Rajia Mim, Santina Hernandez, Linda Fleisher, Kelsey Karpink, Enida Selmani, Aysha Tahsin, Lynne Wagner, Michelle Weinberg, Kuang-Yi Wen, Elisabeth Wood, Angela R. Bradbury

Department of Medical Oncology Faculty Papers

Background: Germline BRCA1 and BRCA2 testing is a standard evidence-based practice, with established risk reduction and cancer screening guidelines for genetic carriers. With Food and Drug Administration approval for poly (adenosine diphosphate ribose) polymerase (PARP) inhibitors in patients with metastatic breast, ovarian, pancreatic, and prostate cancer, there is an additional therapeutic rationale for testing all patients with these cancers for germline BRCA1 and BRCA2 mutations. However, many at-risk patients do not have access to genetic services, leaving many genetic carriers unidentified.

Objective: The eREACH (A Randomized Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in …


Effect Of Chalcogen-Phosphorus Substituents On Enediynes Undergoing The Bergman Cyclization, Marcos Hendler, Travis Greene, Dominic A. Siriani, Carol A. Parish Aug 2025

Effect Of Chalcogen-Phosphorus Substituents On Enediynes Undergoing The Bergman Cyclization, Marcos Hendler, Travis Greene, Dominic A. Siriani, Carol A. Parish

Chemistry Faculty Publications

We have theoretically characterized electrocyclizations of chalcogen-phosphorus-containing enediynes. We performed quantum calculations at the BS-(U)­CCSD/cc-pVDZ level to analyze the geometries and energetics of two different cyclization pathways, each consisting of the first three chalcogens (oxygen, sulfur, and selenium). The first pathway involved the cyclization of the chalcogen-phosphorus substituents followed by Bergman cyclization, while the second pathway proceeded via Bergman cyclization followed by chalcogen-phosphorus cyclization. To more accurately understand the energies of the diradicals involved in each pathway, we also performed spin-flip characterizations using UHF reference wave functions and the spin-flip formulation of the equation-of-motion coupled cluster theory with singles and …


Rising Costs Of Higher Education In United States And Student Debt, Mona Muzammil, Muzammil Arshad, Washain Muzammil Aug 2025

Rising Costs Of Higher Education In United States And Student Debt, Mona Muzammil, Muzammil Arshad, Washain Muzammil

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

100 years ago, college tuition at prestigious Ivy League colleges such as Harvard and Brown was about $130 per year. Even when adjusted for inflation, today's cost of higher education has increased dramatically to the point where a college education is shifting further out of reach for many Americans. This book explains the essential concepts in the debate regarding the staggering costs of higher education, supplying ten original essays by higher education policy experts, a lively historical narrative that provides context to current issues, and systematic guides to find additional sources of information on the subject.

Written from a historian's …


The Complexity Of Promoting Physical Activity In English State Primary Schools: An In-Depth Qualitative Analysis Of The Role Of Social Context, Robert Walker, Danielle House, Alice Porter, Ruth Salway, Simona Kent-Saisch, Michael Beets Ph.D., David Revalds Lubans, Frank De Vocht, Russell Jago Aug 2025

The Complexity Of Promoting Physical Activity In English State Primary Schools: An In-Depth Qualitative Analysis Of The Role Of Social Context, Robert Walker, Danielle House, Alice Porter, Ruth Salway, Simona Kent-Saisch, Michael Beets Ph.D., David Revalds Lubans, Frank De Vocht, Russell Jago

Faculty Publications

Background

Primary schools present an opportunity to equitably promote physical activity. To date, school-based interventions have had limited success. Contextual differences between schools could be a key factor that contributes to this lack of impact. However, the elements that constitute a school’s social context (i.e. the organisational, political, cultural, and sociodemographic characteristics) and how they might impact on primary school physical activity are unclear. The aims of this study were to conduct an in-depth qualitative analysis of state primary school social context related to physical activity and, using this analysis, provide recommendations for policy and practice.

Methods

We conducted one-to-one …