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“What Are We And What’S Coming Next?”: Queer People’S Experiences During Sociopolitical Unrest In The Us, Ariana Cristal Morales Nov 2025

“What Are We And What’S Coming Next?”: Queer People’S Experiences During Sociopolitical Unrest In The Us, Ariana Cristal Morales

Master's Theses

Queer (lesbian, gay, bisexual, transgender, queer, or other gender and sexual identities) folx have become a major focal point during political elections. As political climates have projected forced attacks towards queer populations, society has followed suit. Investigation on the impacts of such changes towards queer folx is important to uncover, as sociopolitical climates have shifted within the last 10 years in the US. The present study utilizes a phenomenological framework to understand the lived experiences of queer participants living in the US from 2015-2025 during political and social shifts. Semi-structured interviews were utilized to explore 10 queer participant’s lived experience …


War Abstracted, Jay Hatfield Nov 2025

War Abstracted, Jay Hatfield

Electronic Theses and Dissertations 2020 - Present

War Abstracted is an exhibition in response to the devastation of war. The body of work encapsulates three years of artistic exploration at Florida Atlantic University. The exhibit is a reaction to contemporary conflicts, both global and domestic. It is neither a glorification nor a condemnation of war. The exhibition reflects my experience as a Marine Corps Scout during the Gulf War, the challenges of reintegrating into society with post-traumatic stress disorder (PTSD), and uncertainty. It also engages broader themes of global warming and gun violence. Through a diverse range of materials, methods, and presentations, the work navigates personal and …


Streamlined Real-Time Qpcr Detection Assay And Nucleic Acid Extraction Protocols For Leaf Scald And Ratoon Stunt Disease In Louisiana, Joao Vitor Pelizzaro Morales Nov 2025

Streamlined Real-Time Qpcr Detection Assay And Nucleic Acid Extraction Protocols For Leaf Scald And Ratoon Stunt Disease In Louisiana, Joao Vitor Pelizzaro Morales

LSU Master's Theses

Leaf scald (LS) and ratoon stunt disease (RSD) are important sugarcane diseases that can cause yield losses. LS and RSD are caused by the vascular system-inhabiting bacteria Xanthomonas albilineans and Leifsonia xyli subsp. xyli, respectively. As using pathogen-free sugarcane propagative material is an important management strategy against LS and RSD, accurate and efficient pathogen detection is crucial. Our study aimed to increase pathogen detection sensitivity and efficiency through a cost-effective real-time PCR protocol and high-throughput DNA extraction methods. A SYBR-based qPCR assay detecting the RSD and LS causal agents was 100 times more sensitive than traditional PCR. Additionally, multiplex …


Sustained Cellular Survival Amid Amyloid Beta (Aβ) Burden, Giselle Shim Nov 2025

Sustained Cellular Survival Amid Amyloid Beta (Aβ) Burden, Giselle Shim

Electronic Theses and Dissertations 2020 - Present

Amyloid beta (Aβ) accumulation is a hallmark of Alzheimer’s disease (AD), persisting in the brain for years. Despite its neurotoxic potential, widespread neuronal death is not consistently observed. Histopathological analysis indicates that most neurons remain viable, suggesting an altered survival state under chronic Aβ burden. This study integrates clinical, imaging, and in vitro evidence to characterize this non-lethal state. FDG-PET imaging reveals reduced glucose metabolism. In vitro, Aβ exposure leads to decreased uptake of glucose and amino acids. Reductions in ATP levels and AMPK activity indicate impaired metabolic regulation. Despite these metabolic disruptions, cell death is not observed, implying a …


Analysis Of The Submergence, Landing, And Navigation Of An Autonomous Underwater Landing Vehicle, Theresa Wainwright Nov 2025

Analysis Of The Submergence, Landing, And Navigation Of An Autonomous Underwater Landing Vehicle, Theresa Wainwright

Electronic Theses and Dissertations 2020 - Present

Autonomous Underwater Landing Vehicles allow for seafloor data to be taken in multiple locations with little to no human intervention. The movement of these vehicles needs to be analyzed through simulated to ensure the correct programming of vehicle missions. This analysis includes the surface navigation, the drift experienced by the vehicle during descent, and the seafloor stability of the vehicle. The results then inform the limitations of this vehicle and the necessary adjustments to subsequent versions. Surface navigation allows understanding of vehicle movement between ascent locations, waypoints, and descent locations. Drift during descent allows for visual of the vehicle’s movements …


Shepherding In France: The Ambiguities Of Caring For Nonhuman Animals In The Roya Valley, France, Daina Pupkevičiūtė Nov 2025

Shepherding In France: The Ambiguities Of Caring For Nonhuman Animals In The Roya Valley, France, Daina Pupkevičiūtė

Journal of Ecological Anthropology

F

For over half a century, wolves in France were extinct. In the absence of predators, the shepherds became accustomed to leaving the sheep roaming freely in the mountains in relative safety. However, at the end of the 1980s, wolves returned, resulting in many victims, conflicts, and a stark division between those either for or against the wolf or otherwise sometimes framed as those against or for the survival of the mountain pastoralism tradition. This text looks at the caring relationships humans, such as shepherds, villagers, and others, have towards sheep, wolves, and the landscape in the Roya Valley in …


The Influence Of Russian Folklore On Perceptions Of Female Heroism, Mariia V. Subbotina Nov 2025

The Influence Of Russian Folklore On Perceptions Of Female Heroism, Mariia V. Subbotina

Heroism Science

This article examines how Russian folklore traditions have shaped cultural perceptions of female heroism. The study addresses the limited attention given to gendered aspects of heroism, particularly “female” models, which are often linked to self-sacrifice and resilience, in contrast to “male” heroism associated with physical strength and risk. As the first stage of a larger project, this research aims to introduce the issue and identify key archetypes of female heroism. Based on an analysis of A.N. Afanasyev’s collection of fairy tales, three central archetypes of active heroines are identified: the Warrior Woman (Marya Morevna), the Wise Maiden/Enchantress (Vasilisa the Beautiful), …


2025 - The Sixth Annual Fall Symposium Of Student Scholars Nov 2025

2025 - The Sixth Annual Fall Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Fall 2025 Symposium of Student Scholars, held in November 2025. Includes abstracts from the presentations and posters.


Fish-Spec: Fast Identification System For Handheld Spectroscopy And Species Classification, Mitchell Sueker, Nicholas Mackinnon, Gregory Bearman, Amanda Tabb, Diane Kim, Rosalee S. Hellberg, Alireza Akhbardeh, Hamid Reza Marateb, Jianwei Qin, Moon Kim, Fartash Vasefi, Hossein Kashani Zadeh Nov 2025

Fish-Spec: Fast Identification System For Handheld Spectroscopy And Species Classification, Mitchell Sueker, Nicholas Mackinnon, Gregory Bearman, Amanda Tabb, Diane Kim, Rosalee S. Hellberg, Alireza Akhbardeh, Hamid Reza Marateb, Jianwei Qin, Moon Kim, Fartash Vasefi, Hossein Kashani Zadeh

Food Science Faculty Articles and Research

Accurate fish species identification is critical to prevent mislabeling and fraud in the seafood industry. We present a handheld multi-mode point spectroscopy system that combines fluorescence (365 and 395 nm excitation) and reflectance measurements in the visible to near-infrared (∼350–900 nm) and short-wave infrared (∼900–1700 nm) regions for rapid, non-destructive classification of fish fillets. Tissue spectra were acquired at 25 positions on 68 fillets from 11 species, in both frozen and thawed states. Feature-level fusion across all four modes enabled higher classification accuracy than any single mode alone. A global machine-learning model classified all species with 85 ± 2.8 %, …


Enhanced Photocatalytic Degradation Of Water Pollutants Using Au/Cds: Tio2 Films Nanocomposites Under Ultra Violet-Visible Irradiation, Zainab K. Mohammed, Souad G. Khalil, Mahdi M. Mutter Nov 2025

Enhanced Photocatalytic Degradation Of Water Pollutants Using Au/Cds: Tio2 Films Nanocomposites Under Ultra Violet-Visible Irradiation, Zainab K. Mohammed, Souad G. Khalil, Mahdi M. Mutter

Baghdad Science Journal

In this work, Au/ CdS: TiO2 film nanocomposites were prepared and deposited on a glass substrate for photocatalytic application. First, sol-gel dip coating thin films of CdS: TiO2 were synthesized. Next, the plasma sputtering technique was used to deposit Au on the CdS: TiO2 thin films. Composite CdS: TiO2 ratios were (1:1, 1:0.25, and 1:0.5). The produced films were studied using X-ray diffraction (XRD) measurements, atomic force microscopy (AFM), field emission scanning electron microscopy (FESEM), and UV-visible spectroscopy. With the addition of TiO2, the energy band gap, as measured by UV-visible spectroscopy, decreased from …


Computer Simulation Of Zonal Adaptive Optics And Assessment Of Its Effectiveness Using Solar Images, Huda Shaker Ali, Raaid Nawfee Hassan Nov 2025

Computer Simulation Of Zonal Adaptive Optics And Assessment Of Its Effectiveness Using Solar Images, Huda Shaker Ali, Raaid Nawfee Hassan

Baghdad Science Journal

Distortions in astronomical images caused by Earth’s turbulent atmosphere can be corrected using Adaptive Optics (AO). A Zonal-AO computer simulation approach for the correction of wavefront distortions in long-range astronomical observations, including those for solar prominences is presented. The primary task is to test the performance of AO system with solar image data. The distorted PSFs (point spread functions) and wavefronts caused by atmospheric turbulence are generated in the simulation, after that measured as well as corrected. The results of analyzing the impact of deformable mirror (DM) actuator stroke on both Strehl ratio as well as root-mean-square error (RMSE) show …


New Local Function In Grill Topological Spaces, Alyasaa Jassim Bidaiwi, R. B. Esmaeel Nov 2025

New Local Function In Grill Topological Spaces, Alyasaa Jassim Bidaiwi, R. B. Esmaeel

Baghdad Science Journal

This Paper introduces a new local function φSζ*in a Grill topological space (X˙, ζ,τ) by using a semi open set, which is a superset of the local function φζ. Additionally, two equivalent operators, Ψs and ΓSthat define topology τSζ, were devised based on φSζ*, along with the presentation of various characteristics and properties of φSζ* and the two equivalent operators, Ψs and ΓS. Additionally, newly created sets with weakly open properties (φSζ …


Radiation Levels And Hazard Indices In Soil Samples From Fuel Stations In Anbar Province, Iraq, Bahaa Ahmed Samir, Anmar Dherar Kosaj Nov 2025

Radiation Levels And Hazard Indices In Soil Samples From Fuel Stations In Anbar Province, Iraq, Bahaa Ahmed Samir, Anmar Dherar Kosaj

Baghdad Science Journal

In this research, measurements and calculations were conducted to determine the activity and radiation hazard indices of radioactive nuclides in 43 petrol stations across Anbar Province, using the high-purity germanium detector (HPGe) at the Radiation Protection Center in Baghdad Province. The highest specific activity was reported for uranium-238 at 64.90 ± 11.00 Bq/kg, while thorium-232 was 32.80 ± 6.00 Bq/kg. Cesium-137 had a specific activity of 12.90 ± 0.60 Bq/kg, and potassium-40 was present at 753.00 ± 49.00 Bq/kg. The lowest specific activity values for uranium-238 were 0.20 ± 0.70 Bq/kg, and for thorium-232, it was 2.00 ± 0.40 Bq/kg. …


The Dynamic Of A Three Species Food Chain Model Under The Influence Of Fear And Wind, Kaherah Ibrahim Hadib, Hiba Abdullah Ibrahim Nov 2025

The Dynamic Of A Three Species Food Chain Model Under The Influence Of Fear And Wind, Kaherah Ibrahim Hadib, Hiba Abdullah Ibrahim

Baghdad Science Journal

This work suggests a system of ordinary differential equations (ODEs) containing a three-species food chain model incorporating wind and fear effects. The properties of the solution, like positivity and bound-ness, were investigated. All equilibrium points (biologically feasible) have been obtained, and the local stability of these equilibriums has been carried out. The global stability outcomes on the equilibrium points under specific restrictions have been established. Also, the persistence restrictions have been investigated. By utilizing Sotomayor’s theorem, the local bifurcation of the suggested model has been inspected. Furthermore, numerical analysis was carried out to ensure the theoretical results obtained by utilizing …


A Heart So White: Musical Reflections On Lady Macbeth's Mind, Caitlyn N. Long Nov 2025

A Heart So White: Musical Reflections On Lady Macbeth's Mind, Caitlyn N. Long

Undergraduate Theses

A Heart So White: Musical Reflections on Lady Macbeth’s Mind reimagines one of Shakespeare’s most infamous characters through a trauma-informed lens. This thesis combines artistic creation with interdisciplinary research in psychology, dramaturgy, and musical theatre studies to explore Lady Macbeth’s psychological unraveling and reclaim her from centuries of villainization. Composing from Lady Macbeth’s perspective allowed for a deeper exploration of her guilt, dissociation, repression, and isolation—symptoms traditionally overlooked in favor of Macbeth’s more visible descent into violence. Through musical motifs, lyrical reinterpretation, and staging concepts, the work seeks to humanize Lady Macbeth and highlight how trauma shapes behavior, relationships, and …


An Essay On Trailblazing With Service Animals Langer, Pilot, Bowie, And Izzie: Preserving Non-Partisan Public Health And The Law, Gary C. Norman Nov 2025

An Essay On Trailblazing With Service Animals Langer, Pilot, Bowie, And Izzie: Preserving Non-Partisan Public Health And The Law, Gary C. Norman

Journal of Law and Health

A direct correlation exists among humans, their animals, and human health and wellness. This article will focus concisely on law students with disabilities and lawyers with disabilities and how they can be empowered to be trailblazers while remaining healthy and well. Salutogenic Model should be optimized by lawyers with disabilities working at the intersection of animal law, disability law, and public health law. Service animals have positive and salubrious impacts upon their handlers in several ways, including psychosocial health and wellbeing. The Grand Architect (or in my Cherokee tradition, "great spirit") continuously partners me with complicated but magnificent dog partners …


Access To Healthcare For Irregular Migrants, Jessica Dykes Nov 2025

Access To Healthcare For Irregular Migrants, Jessica Dykes

Journal of Law and Health

Access to Healthcare for Irregular Migrants is an assessment of the right to life, security of the person, and non-discrimination as viewed through the lens of Nell Toussaint's legal battle. It tells the compelling story of an irregular migrant's battle for access to health care. Highlighting a gap in the Canadian healthcare system, this piece raises valuable questions about why that gap exists. Toussaint's experiences with multiple levels of the legal system, both in Canada and internationally, are included. It tells the story from when Ms. Toussaint entered Canada to the present; wherein the matter remains before the court.

This …


Madagascar's Urban Lemur Meat Trade, Cortni Borgerson, Be Noel Razafindrapaoly, Be Jean Rodolph Rasolofoniaina Nov 2025

Madagascar's Urban Lemur Meat Trade, Cortni Borgerson, Be Noel Razafindrapaoly, Be Jean Rodolph Rasolofoniaina

Department of Anthropology Faculty Scholarship and Creative Works

As the world's most endangered mammals, lemurs are key to understanding how humans and wildlife can sustainably coexist. We present the first national assessment of the urban lemur meat trade. We interviewed 2600 participants across 17 cities to determine its scale, target species, distribution, and drivers. We reveal a considerable trade, with thousands of threatened lemurs sold annually. This trade is largely hidden, with 95% of sales occurring directly between suppliers and a trusted clientele, and targets some of the nation's most endangered species, often during critical breeding seasons. While entrepreneurial peri-urban suppliers are lured by a dependable economic opportunity, …


Economic Convergence, Intragenerational Economic Mobility, And Inequality In A Native Amazonian Small-Scale Society Of Indigenous People In Bolivia, Ricardo Godoy, Jonathan Bauchet, Victoria Reyes-Garcia, Eduardo A. Undurraga Nov 2025

Economic Convergence, Intragenerational Economic Mobility, And Inequality In A Native Amazonian Small-Scale Society Of Indigenous People In Bolivia, Ricardo Godoy, Jonathan Bauchet, Victoria Reyes-Garcia, Eduardo A. Undurraga

Department of Agricultural Economics Faculty Publications

Adult intragenerational mobility reflects society’s ability to reward effort and tame society-wide inequality. In developed economies, mobility is modest and correlates negatively with economic inequality. Little is known quantitatively from direct observations about long-term intragenerational mobility in small-scale societies of the Global South. To assess the external validity of findings about patterns of intragenerational mobility from developed economies, we use a yearly survey panel dataset (2002–2010) of adults from a society of native Amazonians (Tsimane’) in Bolivia practicing farming, fishing, hunting, and plant gathering. We estimate (a) convergence rates (or the speed of catch up) of adults in the bottom …


Renewal Of The Mind: Forgiveness Through The Lens Of Christian Faith And Neuroscience, Khelen Walsh Nov 2025

Renewal Of The Mind: Forgiveness Through The Lens Of Christian Faith And Neuroscience, Khelen Walsh

University Honors Theses

Within Christian theology, forgiveness is a foundational concept that is often understood as a divine command, a spiritual practice, and a path toward reconciliation and personal growth. Recent neuroscientific research further supports this viewpoint, providing data that shows forgiveness engages neural systems responsible for emotional regulation, empathy, moral reasoning, and perspective-taking. Through neuroplasticity, repeated acts of forgiveness reshape the brain, strengthen connections between prefrontal and limbic regions, reduce amygdala reactivity, and enhance emotional stability and cognitive flexibility. Although forgiveness offers many benefits, modern culture frequently distorts its meaning, framing it as a sign of weakness, gullibility, or a form of …


Evaluating The Effectiveness Of Clinical Practice Guideline Adherence For Patellofemoral Pain (Knee-Capp): Protocol For A Multisite, Parallel-Arm Randomized Clinical Trial In The Military Health System, Emma H. Beisheim-Ryan, Timothy C. Mauntel, Daniel I. Rhon, Charity G. Patterson, Nathan Parsons, Scott Paradise, Megan H. Roach, Marisa Pontillo, Sara R. Gorczynski, Ariana Emory, Shawn Farrokhi Nov 2025

Evaluating The Effectiveness Of Clinical Practice Guideline Adherence For Patellofemoral Pain (Knee-Capp): Protocol For A Multisite, Parallel-Arm Randomized Clinical Trial In The Military Health System, Emma H. Beisheim-Ryan, Timothy C. Mauntel, Daniel I. Rhon, Charity G. Patterson, Nathan Parsons, Scott Paradise, Megan H. Roach, Marisa Pontillo, Sara R. Gorczynski, Ariana Emory, Shawn Farrokhi

Physical Therapy Faculty Articles and Research

Importance

Patellofemoral pain (PFP) frequently affects military personnel, caused by the physical demands of duty-related training. Clinical practice guidelines (CPG) can guide PFP management, yet physical therapist practice patterns vary and often exclude CPG-recommended, evidence-based interventions. Objective

The Evaluating the Effectiveness of Clinical practice guideline Adherence for Patellofemoral Pain (knEE-CAPP) trial assesses whether a CPG-adherent physical therapy approach more significantly reduces pain, disability, health care utilization, and analgesic medication prescription in Service members with PFP as compared to usual physical therapist care. Design

This is a multisite, parallel arm randomized controlled trial. Setting

The study will be conducted at 4 …


Interventions To Enhance Care Partner Performance And Participation In Alzheimer's And Neurocognitive Disorders: A Systematized Review, Ainslie Suyko, Addison Werner, Elizabeth A. Stacy, Danielle M. Westmark, Stacy Smallfield, Molly A. Whitlow Nov 2025

Interventions To Enhance Care Partner Performance And Participation In Alzheimer's And Neurocognitive Disorders: A Systematized Review, Ainslie Suyko, Addison Werner, Elizabeth A. Stacy, Danielle M. Westmark, Stacy Smallfield, Molly A. Whitlow

Student Systematized Reviews: Occupational Therapy

Purpose: Care partners of people with Alzheimer’s disease (AD) and related neurocognitive disorders (NCDs) often experience disrupted routines, reduced self-care, and limited participation in meaningful occupations. Occupational therapy (OT) supports care partners’ engagement in health-promoting activities and sustainable caregiving (Rhodus et al., 2023). This systematized review examined interventions that enhance care partner performance and participation.

Design: Peer-reviewed, English-language articles were included if they involved adult care partners of individuals with AD or NCDs, implemented an intervention within the scope of OT, and used quantitate research designs.

Method: A total of 319 articles from MEDLINE, CINAHL, and Scopus were screened; 61 …


Field Canals Improvement Projects Duration Prediction: A Comparative Analysis Of Machine Learning Models, Hania Ghouse, Ukaegbu Chinonso Ishmael, Edgar Dario Obando-Paredes, Hashem Shafik Shakir, Ali Al-Bayaty Nov 2025

Field Canals Improvement Projects Duration Prediction: A Comparative Analysis Of Machine Learning Models, Hania Ghouse, Ukaegbu Chinonso Ishmael, Edgar Dario Obando-Paredes, Hashem Shafik Shakir, Ali Al-Bayaty

Electrical and Computer Engineering Faculty Publications and Presentations

There are several essential elements in project construction management to be studied appropriately, and priority to these elements, such as cost and duration, is predominantly interesting to be investigated. In this research, the duration of field canal improvement projects (DFCIP) was predicted using two relatively new machine learning (ML) models - the Multivariate Adaptive Regression Spline (MARS) and Extreme Learning Machine (ELM). The targeted DFCIP was calculated using other dependent parameters, such as the length of the pipe, years of construction, the geographical zone of the network, the supplied area with water, and finally the actual cost of the field …


An Experiential Learning Lab Activity On Skeletal Muscle Physiology In Undergraduate Md Pre-Clerkship Curriculum, Angela Martinez, Daniel Salinas, Meyer Maddox, Kelsey A. Potter-Baker, Amin Shah Nov 2025

An Experiential Learning Lab Activity On Skeletal Muscle Physiology In Undergraduate Md Pre-Clerkship Curriculum, Angela Martinez, Daniel Salinas, Meyer Maddox, Kelsey A. Potter-Baker, Amin Shah

School of Medicine Publications

Experiential learning is an important part of the medical education curriculum. Due to clinical relevance of skeletal muscle strength in evaluating patients’ complaints of muscle weakness or imbalance, skeletal muscle physiology is an important concept with extensive potential for experiential learning opportunities. Our goal was to establish an experiential learning skeletal muscle physiology lab activity that would improve undergraduate MD pre-clerkship students’ skill to collect muscle force measurements using a hand-held dynamometer (HHD) and expand knowledge of core physiological concepts. We developed a muscle lab activity where students performed two experiments using an HHD: (1) The Elbow Flexion Experiment and …


Harnessing Hyperspectral Imaging And Deep Learning For Terrestrial Habitat Mapping In Arid Landscapes: A Case Study In Saudi Arabia, Ali Elgendy, Hesham Morgan, Brandon Tran, Rejoice Thomas, Tamer Ismail, Yehya Kh. Shehadeh, Ahmed Elgharib, Ahmed Abdullah Al-Dughairi, Ali El Muburak, Khaled Allam Harhash, Hesham El-Askary Nov 2025

Harnessing Hyperspectral Imaging And Deep Learning For Terrestrial Habitat Mapping In Arid Landscapes: A Case Study In Saudi Arabia, Ali Elgendy, Hesham Morgan, Brandon Tran, Rejoice Thomas, Tamer Ismail, Yehya Kh. Shehadeh, Ahmed Elgharib, Ahmed Abdullah Al-Dughairi, Ali El Muburak, Khaled Allam Harhash, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Arid ecosystems remain under-mapped at actionable scales despite their ecological importance. Decision makers lack reliable, high-resolution habitat maps in drylands to prioritize protection and target restoration. This research integrates spaceborne hyperspectral imaging from the Environmental Mapping and Analysis Program (EnMAP) with deep learning semantic segmentation models to produce an updated level of habitat classification based on the International Union for Conservation of Nature (IUCN) for part of the Imam Turki bin Abdullah Royal Reserve, Saudi Arabia. Using ground control points and the full EnMAP spectral cube without band selection, U-Net and DeepLabV3+ architectures were each implemented with VGG19 and ResNet-101 …


Gboost-Ctl: A Novel Method In Multi-Tissue Transcriptome-Wide Associations Studies In Cross-Tissue Learner Incorporating Gwas Information, Md Mutasim Billah, Hairong Wei, Fengzhu Sun, Kui Zhang Nov 2025

Gboost-Ctl: A Novel Method In Multi-Tissue Transcriptome-Wide Associations Studies In Cross-Tissue Learner Incorporating Gwas Information, Md Mutasim Billah, Hairong Wei, Fengzhu Sun, Kui Zhang

Michigan Tech Publications

Genome-wide association studies (GWAS) have uncovered numerous genetic variants linked to complex human diseases, yet linking these variants to transcripts and tissues that drive pathology remains difficult. Multi-tissue transcriptome-wide association studies (TWAS) offer a powerful bridge, but existing analytical methods have some limitations, either by discarding important signals by separately analyzing and then aggregating results across tissues, implying imputation models in individual tissues, or fusing them with weights that ignore how much GWAS signal each tissue actually carries. Therefore, most of the existing methods do not work uniformly across different GWAS cohorts. Here, we propose GBoost-CTL - a GWAS-boosted cross-tissue …


Timeless Poetry, Xuning Li Nov 2025

Timeless Poetry, Xuning Li

Theses

Timeless Poetry reimagines classical Chinese poetry through contemporary digital tools, transforming ancient verse into immersive visual experiences. Using Cinema 4D and Blender for 3D modeling and ink-wash–inspired rendering, the project reconstructs poetic landscapes as cinematic-style environments that invite viewers to encounter traditional imagery through modern visual language. Postcards—chosen for their nostalgic and emotional resonance—serve as both a physical anchor and an interactive trigger: when scanned, each card reveals an AR visuals that reveal the scene in motion. This hybrid design bridges past and present, showing how technology can enhance, rather than replace, cultural heritage by offering new entry points for …


Analysis And Interpretation Of Somatic Nmd-Escaping Variants In Oncogenes And Dual-Function Genes Across Adult And Pediatric Cancer Cohorts, Runjun D Kumar, Jiaming Li, Mark R Wilkinson, Lu Wang, Jeffery M Klco, Li Tang, Jennifer L Neary, Sharon E Plon, Patrick R Blackburn Nov 2025

Analysis And Interpretation Of Somatic Nmd-Escaping Variants In Oncogenes And Dual-Function Genes Across Adult And Pediatric Cancer Cohorts, Runjun D Kumar, Jiaming Li, Mark R Wilkinson, Lu Wang, Jeffery M Klco, Li Tang, Jennifer L Neary, Sharon E Plon, Patrick R Blackburn

Faculty, Staff and Students Publications

Interpreting protein-truncating variants predicted to escape nonsense-mediated decay (NMDe) based on the 50-bp rule is challenging due to their variable consequences. The Clinical Genome Resource, Cancer Genomics Consortium, and Variant Interpretation for Cancer Consortium recommendations focus on tumor suppressor genes where NMDe variants may result in loss-of-function. However, guidance for interpreting NMDe variants in oncogenes and dual-function genes remains limited. To address this gap, we screened the Catalogue of Somatic Mutations in Cancer, focusing on oncogenes and dual-function genes with ≥10 NMDe variants supported by published functional studies. This analysis prioritized 15 genes exhibiting two distinct NMDe patterns resulting in …


A Journey Into The Mysterious Quantum Realm, Kien Bui Nov 2025

A Journey Into The Mysterious Quantum Realm, Kien Bui

Osmosis Magazine

Toward the end of the 18th century, many scientists believed that all the fundamental laws of physics had already been discovered. Falling apples obeyed Newton’s laws of motion, spinning compasses were explained by Maxwell’s unification of electricity and magnetism, and steam engines drove the first industrial revolution through the rise of thermodynamics. Lord Kelvin stated, “[t]here is nothing new to be discovered in physics now, all that remains is more and more precise measurement.” Only “two small clouds,” he warned, were the two remaining mysteries: black-body radiation and the theory of light. These small clouds, however, turned out to be …


From Sci-Fi To Reality: Could There Be Life On Mars?, Matea Šarkinović Nov 2025

From Sci-Fi To Reality: Could There Be Life On Mars?, Matea Šarkinović

Osmosis Magazine

Have you ever wondered: Are we alone in the universe? Well, scientists hope to answer the age-old question and they believe that Mars could hold the answer. The red planet has been identified as a potential home to life beyond Earth, and this article aims to explore what makes Mars such a strong candidate. Understanding the conditions on extraterrestrial objects is key to determining if our existence is a unique phenomenon or if we are the product of a recurring event that happens throughout the universe.