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Promoting Safe And Effective Ciwa-Ar Protocol Adherence On An Inpatient Psychiatric Unit Through An Educational Reference Poster: A Quality Improvement Project, Kenan J. Gray Jan 2026

Promoting Safe And Effective Ciwa-Ar Protocol Adherence On An Inpatient Psychiatric Unit Through An Educational Reference Poster: A Quality Improvement Project, Kenan J. Gray

Master's Theses and Capstones

Abstract

Background: Alcohol withdrawal syndrome (AWS) can progress to seizures, delirium tremens, and autonomic instability. The Clinical Institute Withdrawal Assessment for Alcohol–Revised (CIWA-Ar) supports symptom-triggered AWS management, but safe use depends on timely nursing assessment, reassessment, and documentation.

Local Problem: On an adult inpatient psychiatric unit, chart audits identified CIWA-Ar protocol adherence gaps, including missed four-hour assessments and one-hour reassessments after lorazepam.

Methods: This quality improvement project used the Plan-Do-Study-Act model. Three educational reference posters were placed in high-visibility staff areas with QR-linked access to the facility’s AWS protocol and CIWA-Ar scoring guidelines. Outcomes were evaluated using pre- and post-intervention …


Improving Nurse Well-Being And Patient Safety Through A Structured Break Buddy System: A Quality Improvement Project, Elizabeth Harrington Jan 2026

Improving Nurse Well-Being And Patient Safety Through A Structured Break Buddy System: A Quality Improvement Project, Elizabeth Harrington

Master's Theses and Capstones

Abstract

Background: Nursing burnout has become an increasing concern due to heavy workloads, staffing shortages, and the inability of nurses to consistently take uninterrupted rest breaks during their shifts. Missed breaks contribute to fatigue, emotional exhaustion, decreased job satisfaction, and an increased risk of patient safety events. Evidence suggests that structured break interventions may improve opportunities for recovery during the workday.

Methods: A quality improvement (QI) project was conducted on a respiratory care unit at a midsized hospital in central New Hampshire using the Plan-Do-Study-Act (PDSA) framework. A microsystem assessment identified inconsistent break-taking as a significant gap. A five-question anonymous …


Introducing Education For Sensory Approaches In Mental Health-Related Emergency Department Visits: A Quality Improvement Project To Enhance Patient-Centered Care, Jesse O'Neill Jan 2026

Introducing Education For Sensory Approaches In Mental Health-Related Emergency Department Visits: A Quality Improvement Project To Enhance Patient-Centered Care, Jesse O'Neill

Master's Theses and Capstones

Background: Barriers to specialty care access have resulted in emergency departments (ED) operating as temporary psychiatric hold facilities for their communities. Patients boarding in the ED are demonstrated to use a disproportionate percentage of facility resources with minimal benefit to the patient. The Institute for Healthcare Improvement identifies the impact of the healthcare environment on patient outcomes and suggests staff training to foster trauma-informed practice culture (Schall et al., 2020).

Local Problem: High-stress healthcare environments can escalate maladaptive patient behaviors and the use of restrictive interventions. Traditional use of restrictive interventions lacks supportive evidence and contradicts person-centered care goals (Molloy …


Framing Migration And Legitimizing Power: A Critical Discourse Analysis Of Suella Braverman’S Illegal Migration Bill, Darren Pullen, Andy Brown, Gui Ying Annie Yang-Heim Jan 2026

Framing Migration And Legitimizing Power: A Critical Discourse Analysis Of Suella Braverman’S Illegal Migration Bill, Darren Pullen, Andy Brown, Gui Ying Annie Yang-Heim

Faculty Publications - College of Education

Language plays a crucial role in shaping public perceptions, reinforcing ideological dominance, and legitimizing government policies. The purpose of this paper is to analyze how linguistic and rhetorical strategies are used as a means to legitimize government authority and construct migrant identities.  This is achieved through an examination of the rhetorical strategies employed by the former UK Home Secretary, Suella Braverman in her speech on the Illegal Migration Bill. Using Critical Discourse Analysis (CDA) and the Sociolinguistic concepts of ideological positioning and social actor representation, this research investigates word choice, lexical framing, and ideological positioning to reinforce dominant migration narratives. …


Scope Of Microbial Transglutaminase For Site-Specific And Oriented Immobilization Of Native Antibodies From Various Host Species, Emily Beitello, Kwame Osei, Faith E. Breausche, Jon A. Friesen, Jeremy D. Driskell Jan 2026

Scope Of Microbial Transglutaminase For Site-Specific And Oriented Immobilization Of Native Antibodies From Various Host Species, Emily Beitello, Kwame Osei, Faith E. Breausche, Jon A. Friesen, Jeremy D. Driskell

Faculty Publications – Chemistry

Modification of antibodies to chemically couple labels or immobilization reagents is essential for developing biosensors. Typically, conjugation occurs through chemical methods that leverage reactive amines and thiols on native antibodies; however, this nonspecific approach can interfere with antibody function. Microbial transglutaminase (mTG) is an enzyme that has been used for site-specific conjugation of chemical modifiers to the Fc region of native antibodies, but thus far mTG-mediated conjugation has been limited to production of antibody-drug conjugates with human IgGs. Here, we assessed the scope and versatility of mTG to target IgGs, with the goal of site-specific conjugation to facilitate oriented …


Investigations Toward A Unified Reaction Pathway Of Thermal And Tbsotf-Mediated Oxidopyrylium-Alkene (5 + 2) Cycloadditions, Adam J. Youman, Samantha N. Rokey, Wentao Guo, Jacob P. Grabowski, Susanna N. Angles, Jacob J. Bulandr, Qing Sun, John R. Goodell, Dean J. Tantillo, T. Andrew Mitchell Jan 2026

Investigations Toward A Unified Reaction Pathway Of Thermal And Tbsotf-Mediated Oxidopyrylium-Alkene (5 + 2) Cycloadditions, Adam J. Youman, Samantha N. Rokey, Wentao Guo, Jacob P. Grabowski, Susanna N. Angles, Jacob J. Bulandr, Qing Sun, John R. Goodell, Dean J. Tantillo, T. Andrew Mitchell

Faculty Publications – Chemistry

Oxidopyrylium-based (5 + 2) cycloadditions are crucial reactions to construct seven-membered carbocycles containing an ether bridge (i.e. oxabicyclo[3.2.1]octanes). Intramolecular silyloxypyrone-based (5 + 2) cycloadditions were investigated and revealed several features: (1) the TBDPS thermal process proceeds via a zwitterionic oxidopyrylium intermediate similar to previously reported TBS variants; (2) the TBSOTf-mediated reaction proceeds through a cationic oxidopyrylium intermediate; (3) quantum chemical calculations predict a stepwise process for an electron-rich dipolarophile for each set of conditions. The thermal silyloxypyrone-based (5 + 2) cycloadditions were extremely dependent on the nature of the dipolarophile and the silyl transfer group. The TBDPS enhances the …


Ordo Ab Chao: Crystallographic Disorder As A Window Into Ionic Liquid Structure, Joseph Cooper, Marija Scheuren, Lara I. Teodoro, Christopher M. Butch, Raychell A. Jerdo, Kylie M. Allen, Mariana E. Toner, Matthias Zeller, Arsalan Mirjafari, Patrick C. Hillesheim Jan 2026

Ordo Ab Chao: Crystallographic Disorder As A Window Into Ionic Liquid Structure, Joseph Cooper, Marija Scheuren, Lara I. Teodoro, Christopher M. Butch, Raychell A. Jerdo, Kylie M. Allen, Mariana E. Toner, Matthias Zeller, Arsalan Mirjafari, Patrick C. Hillesheim

Faculty Publications – Chemistry

Despite being intended to resist crystallization, ionic liquids (ILs) quite frequently form solids, albeit with low melting points. The design motifs that lower melting points can leave measurable signatures in the solid state, manifesting as crystallographic disorder, and often give rise to metastable liquid states. While sometimes treated as experimental complications, such features provide a valuable window into the structural origins of IL phase behavior. Herein, we report a crystallographic study of a series of benzylated ILs that crystallize either directly or from long-lived supercooled melts. Single-crystal X-ray diffraction, supported by computational modeling and statistical analyses, provides structural evidence that …


Embryonic Option-Hood, Elissa Philip Gentry, Mackenzi Barrett, W. Kip Viscusi Jan 2026

Embryonic Option-Hood, Elissa Philip Gentry, Mackenzi Barrett, W. Kip Viscusi

SMU Law Review

A frozen embryo represents not merely a potential human life but a deferred decision to trigger this potential. Parties value this opportunity for deferral because it allows them to retain the option to attempt conception after any uncertainty about future events or desires has resolved. Failing to recognize this “option value” of embryos has resulted in confusion over the best approach to allocating ownership of embryos and calculating damages for reproductive harms. This Article provides a novel paradigm showing that embryos should be treated as neither persons nor mere property; instead, a significant portion of their value is in their …


Racing To Safety: Tax Policy For Ai Safety-By-Design, Mirit Eyal-Cohen, Yonathan Arbel Jan 2026

Racing To Safety: Tax Policy For Ai Safety-By-Design, Mirit Eyal-Cohen, Yonathan Arbel

SMU Law Review

The White House recently announced its vision of artificial intelligence (AI) policy: AI development is a race and America must win it. To that end, a new America’s AI Action Plan directs federal agencies and states to remove regulatory barriers to AI development and accelerate innovation. This approach leaves limited room for regulatory measures that would address the safety risks of powerful AI systems: their behavior in novel domains remains unpredictable, their decision-making opaqueness, and their alignment with human values is uncertain. While experts warn of large-scale accidents, policymakers find themselves in a bind: Regulate AI and cede ground to …


Predictive Protest Policing, Christian Powell Sundquist Jan 2026

Predictive Protest Policing, Christian Powell Sundquist

SMU Law Review

The policing of dissent in America is undergoing a radical transformation that threatens the fundamental right to protest. Demonstrations are no longer merely surveilled; they are algorithmically suppressed. Law enforcement agencies increasingly deploy algorithmic social media surveillance to predict protest violence, forecasting potential “riots” and justifying militarized responses before a single demonstrator takes to the street. This Article identifies and challenges what it terms “predictive protest policing,” arguing that these systems do not objectively detect threats but actively construct them, disproportionately targeting racial justice demonstrations. Drawing on evidence from the federal response to immigration protests in Minneapolis, the preemptive policing …


Preserving Gender Norms Through Harm-Based Reasoning: The Best Interest Of The Child Standard And Transgender Parents, Ariël Decoster Jan 2026

Preserving Gender Norms Through Harm-Based Reasoning: The Best Interest Of The Child Standard And Transgender Parents, Ariël Decoster

SMU Law Review

Contemporary custody law purports to have moved beyond dominant gendered understandings of parental roles and family life by resolving disputes under the ostensibly neutral “best interest of the child” (BIC) standard rather than through the explicitly gendered rules that once governed custody adjudication. This Article examines custody disputes involving transgender parents to reveal a structural feature of custody adjudication under the BIC standard, namely the continued reproduction of dominant gender norms under the guise of a neutral legal standard.

Analyzing transgender custody cases alongside scholarship documenting how the BIC standard’s indeterminacy has enabled bias against other marginalized parents, the Article …


Asymmetric Synthesis Of The Hiv Protease Inhibitor Tmc-126, A Pmx Antimalarial Protease Inhibitor, And A Putative Covid-19 Inhibitor Using A Highly Stereoselective Glycolate Aldol Addition Reaction Pathway, Kweku Amaning Affram, Austin Carter, April Breede, Alexandra Kimsey, Godson Hemeson, Bader Semakieh, Moses Martinez, Emmanuel Ayim, Joy Odeh, Shawn R. Hitchcock Jan 2026

Asymmetric Synthesis Of The Hiv Protease Inhibitor Tmc-126, A Pmx Antimalarial Protease Inhibitor, And A Putative Covid-19 Inhibitor Using A Highly Stereoselective Glycolate Aldol Addition Reaction Pathway, Kweku Amaning Affram, Austin Carter, April Breede, Alexandra Kimsey, Godson Hemeson, Bader Semakieh, Moses Martinez, Emmanuel Ayim, Joy Odeh, Shawn R. Hitchcock

Faculty Publications – Chemistry

An asymmetric glycolate aldol addition pathway was developed for the synthetic preparation of a series of protease inhibitors based on the hydroxyethylamine structural motif. A single glycolate aldol adduct derived from a highly diastereoselective (≥95:5 d.r.) asymmetric aldol reaction served as the starting point for the synthesis of the inhibitors. The starting material is easily prepared and purified via recrystallization on multigram scales. This work describes the synthesis of the HIV protease inhibitor TMC-126, the Plasmepsin X (PMX) inhibitor 49c for the treatment of malaria, and a computationally derived inhibitor for the 3CLpro of the SARS-CoV-2 from a single common …


Association Between Internet Use For Health Information And Alzheimer’S Disease Diagnosis Among Older Adults With Diabetes In The United States: Examining Racial And Gender Disparities, Henry M. Zeidan Jan 2026

Association Between Internet Use For Health Information And Alzheimer’S Disease Diagnosis Among Older Adults With Diabetes In The United States: Examining Racial And Gender Disparities, Henry M. Zeidan

College of Graduate Studies: Theses & Dissertations

This study uses data from the National Health and Aging Trends Study (NHATS) Round 13, collected in 2024, to examine whether internet use for health information is associated with Alzheimer’s disease diagnosis among older adults with diabetes in the United States. Given the rising adoption of digital health, understanding who benefits from online health resources is increasingly important. The research also examines whether these associations differ across racial and gender groups, offering insight into potential disparities in digital health engagement and cognitive outcomes. Findings from this study will inform clinical practice, public health programming, and strategies to ensure equitable access …


Math Toxicity: A Psychoanalytic Examination Of Blips And Belonging In Mathematics Education, Kimberly R. Kirstein Jan 2026

Math Toxicity: A Psychoanalytic Examination Of Blips And Belonging In Mathematics Education, Kimberly R. Kirstein

College of Graduate Studies: Theses & Dissertations

This dissertation examines how secondary mathematics education functions not only as a curricular and institutional structure but as a lived, relational, and affective experience for students. While mathematics education research has extensively documented patterns of achievement, access, and anxiety, far less attention has been given to how students come to experience mathematics as a site of threat, shame, and diminished worth. This study introduces the concept of math toxicity to describe the cumulative harm produced when mathematics operates as a gatekeeping mechanism that links performance to identity and value. Drawing on historical analysis, psychoanalytic theory, and autobiographical inquiry, this research …


Celebrities, Personalities, And Drinking Styles, Madeleine Krueger Jan 2026

Celebrities, Personalities, And Drinking Styles, Madeleine Krueger

College of Graduate Studies: Theses & Dissertations

This study replicated and extended the findings of Hill et al. by examining the influence of sociocultural factors, vulnerable and grandiose narcissism, and related psychological variables on drunkorexia behaviors. The replication was expanded to include body dissatisfaction and celebrity worship, as prior literature suggests these variables may be strongly associated with disordered eating and alcohol-related compensatory behaviors. Results indicated that body dissatisfaction emerged as a significant predictor of drunkorexia, supporting previous research that links negative body image with maladaptive weight-control behaviors surrounding alcohol consumption. Several limitations should be noted, including the use of a single-university sample, reliance on a cross-sectional …


Influence Of The Sst K-Ω Stress-Limiter Coefficient On Transonic Shock Buffet Prediction For The Oat15a Supercritical Airfoil, Melinawo Vowotor Jan 2026

Influence Of The Sst K-Ω Stress-Limiter Coefficient On Transonic Shock Buffet Prediction For The Oat15a Supercritical Airfoil, Melinawo Vowotor

College of Graduate Studies: Theses & Dissertations

Transonic shock buffet predictions using the Shear Stress Transport (SST) k–ω turbulence model are known to be sensitive to the stress-limiter coefficient a₁, yet no systematic investigation of this sensitivity exists. This thesis presents a parametric study of a₁ for two-dimensional URANS simulation of shock buffet on the OAT15A supercritical airfoil at M = 0.73 and Re = 3 × 10⁶. Eleven a₁ values (0.25–0.37) are examined at α = 3.5°, and a matrix of five a₁ values across five angles of attack (3.0°–3.9°) maps the interaction with incidence. The results reveal that a₁ acts as a bifurcation parameter: a …


Professional Learning Community Implementation And Perceptions Of Influence On School Culture, Herbert L. Chambers Jr. Jan 2026

Professional Learning Community Implementation And Perceptions Of Influence On School Culture, Herbert L. Chambers Jr.

College of Graduate Studies: Theses & Dissertations

As school leaders strive to achieve educational success at all levels in schools, this research provided educational professionals with feedback on how the implementation of professional learning communities (PLCs) is perceived as influencing school culture. The purpose of this non-experimental quantitative survey design was to examine how educators perceived that school culture is influenced by the practice of PLCs. Descriptive statistics were calculated for 57 survey items. This research design provided the perceptions of school leaders, teachers, and support staff at the elementary, middle, and high school levels based on five identified dimensions of the Professional Learning Community Assessment – …


Cogram: A Computational Pipeline For Genome Assembly And Reconstruction Using Graph Neural Networks, William Coggins Jan 2026

Cogram: A Computational Pipeline For Genome Assembly And Reconstruction Using Graph Neural Networks, William Coggins

College of Graduate Studies: Theses & Dissertations

Genome assembly — the reconstruction of a complete DNA sequence from short, overlapping reads — remains a fundamental challenge in computational biology. A central difficulty is distinguishing true genomic overlaps from spurious connections arising from repetitive sequences, a task that traditional assemblers address through hand-tuned heuristic rules applied to de Bruijn or overlap graphs. This thesis introduces COGRAM (Coggins–Ramasamy Assembly Method), a genome assembly pipeline that reframes sequence reconstruction as an edge classification task on a k-mer overlap graph, replacing heuristic graph cleaning with a learned model.

COGRAM constructs a directed overlap graph from raw sequencing reads using a k-mer …


Pile Setup Effects On Driven Piles In Southeastern Coastal States, Peya Sharif Jan 2026

Pile Setup Effects On Driven Piles In Southeastern Coastal States, Peya Sharif

College of Graduate Studies: Theses & Dissertations

The resistance of driven piles typically increases with time after installation, a phenomenon known as pile setup. This behavior is primarily associated with the dissipation of excess porewater pressure and the progressive reconsolidation of soil surrounding the pile shaft, particularly it is observed in cohesive soils. Although several empirical and analytical models have been proposed to estimate pile setup, their practical implementation in foundation design remains limited due to uncertainties associated with soil conditions, pile geometry, resistance variability, and time dependent behavior. To address some of these uncertainties, this study collected 221 pile load test data at the End of …


Spieltrieb, Edward F. Newcomb Jan 2026

Spieltrieb, Edward F. Newcomb

College of Graduate Studies: Theses & Dissertations

This thesis investigates the creative and pedagogical intersections of nostalgia, play, and neurodivergent experience through a mixed-media studio practice. Grounded in Friedrich Schiller’s concept of Spieltrieb—the human drive to play as a balance between sensual and rational impulses—this work explores how childhood memory, instinct, and impulsive mark making inform both artistic production and art education.

Drawing on theoretical frameworks by Susan Sontag and John Berger, the work resists overinterpretation in favor of sensory immediacy, inviting viewers into direct, embodied encounters with material form. Sontag’s critique of mimetic representation and Berger’s analysis of reproducibility and context inform a practice that …


The Monster Consuming American Education: An Ethnodramatic Exploration Of Standardized Testing And Student Stress, Jennifer Bagley Jan 2026

The Monster Consuming American Education: An Ethnodramatic Exploration Of Standardized Testing And Student Stress, Jennifer Bagley

College of Graduate Studies: Theses & Dissertations

This study looks at how elementary students experience Standardized Testing, focusing on the emotional and physical effects of the Georgia Milestones Assessment System (GMAS). Most research on high-stakes testing focuses on scores, accountability, and policy, but fewer studies look at how students actually describe these experiences. Grounded in Cultural Studies and informed by Critical Pedagogy, this study examines how students interpret and make meaning of their testing experiences within the broader culture of accountability and standardized assessment. This study focuses on student voices to better understand what testing feels like for them and how they make sense of it in …


Evaluating Benthic Macroinvertebrate Communities In Streamside Management Zones In Private, Working Forests, Haley Vaglienti Jan 2026

Evaluating Benthic Macroinvertebrate Communities In Streamside Management Zones In Private, Working Forests, Haley Vaglienti

College of Graduate Studies: Theses & Dissertations

Forestry operations can alter riparian vegetation and increase sediment and nutrient inputs to streams, affecting water quality and aquatic biota. Forestry best management practices (BMPs) including streamside management zones (SMZs) are designed to mitigate those effects by reducing sediment delivery and moderating temperature, flow, and nutrient regimes. We assessed ecological integrity at 24 intermittent stream sites with SMZs in private, working forests across the Piedmont and Southeastern plains of Georgia. At each site, we conducted physical habitat evaluations and characterized benthic macroinvertebrate assemblages. Sites represented a gradient of habitat conditions, SMZ widths, and pine stand ages, allowing for comparisons of …


The Effect Of In-Game Cervical Exercises On Shoulder Internal Rotation Range Of Motion And External Rotator Strength In Baseball Pitchers, Vincent Ceasrine, Christine Ferraro, Jason K. Grimes Jan 2026

The Effect Of In-Game Cervical Exercises On Shoulder Internal Rotation Range Of Motion And External Rotator Strength In Baseball Pitchers, Vincent Ceasrine, Christine Ferraro, Jason K. Grimes

Physical Therapy Faculty Publications

Background

Consensus is lacking regarding the underlying cause of two prevalent risk factors for shoulder and elbow pain in overhead throwing athletes: loss of shoulder internal rotation (IR) range of motion (ROM) and strength of the external rotators (ER). Consideration of cervical spine contribution may have important implications for rehabilitation and coaching of overhead throwers.

Purpose

The purpose of this study was to investigate the effect of performing active cervical retraction and retraction with extension exercises between innings of pitching a simulated game on shoulder IR ROM and ER strength following completion of the game.

Study Design

Randomized controlled study …


Planning A Clinical Practice Guideline Revision For A Core Set Of Outcome Measures In Adults Undergoing Neurologic Physical Therapy, Part 1: Assessing Dissemination And Scholarly Uptake, Jennifer Moore, Jane E. Sullivan, Marghuretta D. Bland, Wendy Romney, Elizabeth Anderl, Zeynep Gulen Erkoc, Kristen Potter Jan 2026

Planning A Clinical Practice Guideline Revision For A Core Set Of Outcome Measures In Adults Undergoing Neurologic Physical Therapy, Part 1: Assessing Dissemination And Scholarly Uptake, Jennifer Moore, Jane E. Sullivan, Marghuretta D. Bland, Wendy Romney, Elizabeth Anderl, Zeynep Gulen Erkoc, Kristen Potter

Physical Therapy Faculty Publications

Introduction

Clinical Practice Guidelines (CPGs) facilitate evidence-based decision-making and standardising care, yet their dissemination and scholarly uptake vary widely. The Core Set of Outcome Measures for Adults With Neurologic Conditions Undergoing Rehabilitation CPG (Core Set) has been broadly referenced within neurologic physical therapy. As the next revision approaches, understanding its scholarly influence, citation patterns, and published feedback is essential. This study evaluated the dissemination and use of the Core Set across the peer-reviewed literature and identified areas for refinement.

Methods

A medical librarian conducted comprehensive searches of Web of Science, CINAHL, and Scopus to identify peer-reviewed English-language articles citing the …


Social And Community Determinants Of Alcohol Use Among Hispanic/Latino College Students: The Role Of Early Adversity And Drinking Motives, Isis A. Garcia-Rodriguez Jan 2026

Social And Community Determinants Of Alcohol Use Among Hispanic/Latino College Students: The Role Of Early Adversity And Drinking Motives, Isis A. Garcia-Rodriguez

Theses and Dissertations

Background. Alcohol use remains one of the most prevalent health-risk behaviors among college students in the United States and is associated with a range of academic, physical, and psychological consequences. Hispanic/Latino college students navigate complex social and cultural environments that may influence alcohol use behaviors, including exposure to early-life adversity, sociopolitical stressors, and culturally grounded sources of resilience. Guided by the Healthy People 2030 Social Determinants of Health (SDOH) framework, this study examined how social and community context factors relate to alcohol use among Hispanic/Latino college students and whether drinking motives function as a psychological mechanism linking social experiences to …


Implementation Of Tg-351 Reference Dosimetry For A 6 Mv Photon Beam In An Mr-Guided Radiotherapy System, Nicholas A. Castellano Jr. Jan 2026

Implementation Of Tg-351 Reference Dosimetry For A 6 Mv Photon Beam In An Mr-Guided Radiotherapy System, Nicholas A. Castellano Jr.

Theses and Dissertations

Magnetic resonance guided radiation therapy (MRgRT) combines magnetic resonance imaging (MRI) and radiation therapy to enable the visualization of anatomy in real time during treatment. The presence of a magnetic field in MRgRT affects charged particle radiation and detector responses, necessitating changes to traditional reference dosimetry procedures. The American Association of Physicists in Medicine (AAPM) Task Group 351 (TG-351) provides a formalism for reference dosimetry in MRgRT. In this study, the TG 351 formalism is used to perform reference dosimetry for a 6 MV flattening filter-free (FFF) photon beam from a Viewray MRIdian MR-Linac radiation therapy system. Beam quality determination, …


De Novo Protein Binding To Zinc Oxide Through Biomineralization Pathways, Jean-Mark A. Francis Jan 2026

De Novo Protein Binding To Zinc Oxide Through Biomineralization Pathways, Jean-Mark A. Francis

Theses and Dissertations

De novo proteins are structurally distinct from proteins found in nature and thus capable of having their amino acid sequence modified to accomplish tasks such as increasing protein-nanoparticle binding without unfolding or decomposing. Zinc Oxide nanoparticles are functionally distinct from their bulk counterparts and are widely used as semiconductors in a variety of fields such as medicine and agriculture. With demand for these nanoparticles increasing, environmentally sustainable methods of Zinc Oxide nanoparticle synthesis are being investigated as an eco-friendly alternative to currently utilized but environmentally hazardous chemical and physical techniques. This research investigates the binding characteristics between Zinc Oxide nanoparticles …


The Relationship Between Symptom Catastrophizing And Sociocultural Factors Among Adults With Persistent Sympathetic Activation Syndromes, Whitney M. Redemer Jan 2026

The Relationship Between Symptom Catastrophizing And Sociocultural Factors Among Adults With Persistent Sympathetic Activation Syndromes, Whitney M. Redemer

Theses and Dissertations

Persistent Sympathetic Activation (PSA) has emerged as a potential unifying mechanism underlying a range of complex chronic health conditions yet remains poorly characterized within biomedical and psychosocial research. Limited research has delineated how PSA manifests across diverse populations or how diagnostic and sociocultural factors shape lived experiences of this phenomenon; thus, the objective of the present study was to examine whether diagnostic certainty – operationalized as provider-confirmed versus self-suspected PSA-related diagnoses – is associated with symptom catastrophizing, and whether this relationship varies as a function of sociocultural factors. Drawing on data from a larger study aimed at characterizing the lived …


Your Left Or Mine: A Journey To Accessibility For Learning Disabilities And Neurodivergence In Stage Combat Pedagogy, Ambria Campbell Jan 2026

Your Left Or Mine: A Journey To Accessibility For Learning Disabilities And Neurodivergence In Stage Combat Pedagogy, Ambria Campbell

Theses and Dissertations

This thesis examines stage combat pedagogy from its inception to the present day through the lens of accessibility for learning disabilities and neurodivergence. Relevant research in education as it relates to disability is analyzed and applied to the field of stage combat pedagogy. What follows is a deconstruction and reconstruction of beginning level stage combat pedagogy to increase accessibility. These ideas are then tested and the results reflected on. This thesis focuses on college level and aged students who are the most likely demographic for beginning stage combat students. The completion of this thesis does not represent an endpoint in …


Dimension Reduction Involving Exogenous Variables With Applications In Manufacturing And Healthcare, Linxi Li Jan 2026

Dimension Reduction Involving Exogenous Variables With Applications In Manufacturing And Healthcare, Linxi Li

Theses and Dissertations

High-dimensional data analysis presents diverse challenges, including the curse of dimensionality, the complexities of working with datasets that combine large feature spaces with limited sample sizes, and difficulties in identifying meaningful relationships among variables. As datasets grow in size and complexity across different fields, it is increasingly important to develop practical approaches for extracting essential information from such data. Dimension reduction methods address these challenges by alleviating the effects of high dimensionality, enhancing the ability to reveal hidden patterns, and uncovering latent structures within the data to support further analysis. Some methods reduce dimensionality while preserving all relevant information, offering …