Digital Commons Network^™

Preparation And In-Vitro Evaluation Of Tizanidine Flash Oral Dispersible Tablet, Ahmed Yousif Fadhel, Yousif K. Younis

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Background: Oral administration is the most common and preferred route for drug delivery. Oral dispersible tablets (ODTs) are solid dosage forms that disintegrate into saliva without the need for water. Tizanidine is a centrally acting muscle relaxant used to manage spasticity from spinal or brain injuries. Preparing it as a flash (ODT) tablet may enhance patient compliance and potentially improve bioavailability by bypassing part of the first-pass metabolism. Methods: Six formulations of tizanidine flash tablets were developed using varying concentrations of mannitol (bulk-forming agent), glycine (to aid tablet collapse), and gelatin (matrix-forming agent). The formulations were evaluated for weight variation, …

Cfd-Based Thermal Performance Analysis Of Dimpled And Grooved Heat Pipes, Mazen M. Othayq, Khalid M. Alanazi

Yanbu Journal of Engineering and Science

Heat-transfer enhancement techniques such as fins, dimples, and grooves are widely employed to improve the thermal performance of heat exchangers; however, their application is often accompanied by increased pressure losses. Most existing studies investigate a single enhancement technique over a limited Reynolds number range, with few comparative analyses conducted at high Reynolds numbers using identical geometries. Therefore, this study numerically investigates the thermal–hydraulic performance of five pipe configurations using Computational Fluid Dynamics (CFD). All geometries share the same diameter (48.34 mm) and length (7.45 m) and are examined over a Reynolds number range of 4,000–57,000. The configurations include: (1) smooth …

Optimizing The Interaction Between Rotational Speed, Tool Geometry, And Cooling Conditions In Friction Stir Welding Of Aa6061, Karwan B. Mohammed, Ayad F. Shahab

Engineering and Technology Journal

Friction stir welding (FSW) is a solid-state joining process. It is widely suitable for welding high-strength aluminum alloys. This study presents a systematic optimization of friction stir welding parameters for AA6061-T6 aluminum alloy by investigating the interaction effects of tool rotational speed, tool pin geometry, and cooling conditions. A Taguchi L27 orthogonal array was employed to examine three rotational speeds (820, 1120, and 1420 rpm), three pin profiles (square, triangular, and tapered), and three cooling conditions (compressed air, water, and crushed ice) while maintain a constant traverse speed of 35 mm/min. Mechanical performance was evaluated through tensile testing and stir-zone …

On-Device Multi-Sensor Fusion With Machine Learning For Continuous Transit Navigation, Hui Ling Shi, Louis Lai, Oliver Dolk, Gul Kamisli Hasanoglu, Si Min Ong

Defensive Publications Series

Mobile navigation applications for public transit can experience degraded performance in environments with poor global positioning system signals, such as subway tunnels, which may cause a user's location display to freeze and guidance to cease. A described on-device system may address this by fusing data from a plurality of sensors, such as a barometer, magnetometer, and accelerometer, on a computing device like a smartphone or wearable device. A lightweight machine learning model can process this sensor data to generate a real-time probability that the user is on a moving transit vehicle. This probability may then be combined with a user's …

Refractive Index Determination Of Rectangular Optical Slabs Using Modified Ray Tracing Method, Ubong Williams Robert, Sunday Edet Etuk, Okechukwu Ebuka Agbasi

Engineering and Technology Journal

The traditional ray tracing method (TRM) for determining the refractive index of optical materials is often time-consuming and poses challenges for individuals with visual impairments. Accurate refractive index determination is essential for selecting materials in optical instruments, optoelectronic devices, and optical communication systems. With the emergence of new materials, there is an increasing need for techniques that overcome the limitations of the TRM. In this study, a Modified Ray Tracing Method (MRTM) incorporating the use of a plane mirror to enhance image localisation and reduce alignment ambiguity was developed for determining the refractive indices of various optical materials, including soda, …

The Impact Of People Interests In Evaluating The Open Public Spaces' Quality In The City Centre, Hasan Hadi, Adil Al-Saidi, Haitham Alshamari

HBRC Journal

The quality of open public spaces in city centres significantly affects people's satisfaction and responses to their built environment. The significance of these areas allow people to assess their performance. this paper addresses the issue of People's interests that affect their evaluation of public urban spaces in city centres. The research applied an ontological methodology that is people's experiences determine the spatial quality of the public spaces in city centres. In order to discover and assess the seven value variables, it recommended diagnosing a random sample of users as a group (A) and (B). The urban space in the historic …

Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik

AUIQ Complementary Biological System

Curcuma zedoaria Rosc. (white turmeric) is a rhizomatous medicinal plant in the Zingiberaceae family, widely used in traditional Asian medicine. In recent years, increasing scientific attention has focused on its diverse pharmacological properties and bioactive constituents. This mini review summarises current knowledge of the phytochemical composition and biological activities of C. zedoaria, with particular emphasis on its antimicrobial, antioxidant, anti-inflammatory, and anticancer effects. Phytochemical investigations using analytical techniques such as GC–MS and HPLC have revealed the presence of numerous bioactive compounds, including sesquiterpenes (example, germacrone, curzerenone, and curdione) and curcuminoids, which contribute to its therapeutic potential. Experimental studies demonstrate …

Synergistic Endocytic Receptor Ligand Receptor Protein 2 In T2dm, Wafaa Raji Alfatlawi

AUIQ Complementary Biological System

Purpose: The glycoprotein molecule known as megalin is present on the proximal renal tubular epithelial cells. With an emphasis on megalin and cubilin levels in T2DM and IR patients, an area that obviously needs more research, this study attempts to give an outline of current knowledge of megalin function in relation to vitamin D and its metabolite (vitamin D receptor and vitamin D binding protein). Materials and Methods: This was a case control comparative study conducted at a endocrine and diabetes center in AL-Imamain Kadumain teaching hospital in Baghdad-Iraq. Study subjects were divided into three groups: 25 with T2DM with …

Commerce Identity Backend For Deterministic Online-To-Offline Transaction Attribution, Keith Hall, Alan Stapelberg

Defensive Publications Series

Connecting a user's online discovery with their offline purchasing behavior can be challenging due to fragmented ecosystems and a lack of visibility at physical point of sale (POS) terminals, which can impede transaction attribution. A headless commerce identity backend system is described that can address this gap by establishing a cloud-based account-level primitive. This primitive may use a payment account reference, a stable, non-sensitive identifier, as a federated key to map a user's account to their offline transactions. Such an architecture can facilitate the ingestion of stock keeping unit-level receipt data from POS terminals (e.g., cash registers, payment kiosks) via …

5t-Isc-Awg Technical Addendum 8, Vesa Olavi Lius

Defensive Publications Series

This Addendum extends the 5T-ISC-AWG Defensive Publication (2026) with a rigorous long-term thermal balance analysis of the bedrock-tunnel condenser, addressing a question that the parent publication acknowledged as a known limitation but did not quantify in detail: how the plant maintains passive operation over decadal timescales when the bedrock condenser is continuously absorbing latent heat of condensation at megawatt-class rates. The analysis confirms that the published Nordic and Mediterranean yields (0.93 and 1.16 ML/day respectively) are fully sustainable in passive 24/7 operation, and identifies the physical mechanisms through which long-term thermal balance is achieved: dew-point-pinning of the warm inlet wall …

Mapping The Void In Electric Vehicle (Ev) Adoption Research: Uncovering Lack Of Socio-Economic Study In The Global South, Satvik Pandey, Rahul Tiwari, Rajat Soni

Mansoura Engineering Journal

Electric Vehicles (EVs) are considered an effective contemporary alternative to Internal Combustion Engine (ICE) vehicles. Research in the domain of EV is being conducted globally across a variety of fields; among them, our study explored research on consumer adoption. Going through the bibliometric analysis of the data taken from the Scopus database, what came to our attention is the minimal amount of work that is done on understanding consumers of EVs. From the literature, we found that consumer preferences are shaped through the influence of several parameters related to EVs, and this influence varies according to the consumer’s socio-economic and …

The Sacrificial Vs. The Luzhinian Figure: Comparing Sacrificial Love In Crime And Punishment, Pride And Prejudice, And A Tale Of Two Cities, Natalie Rose Kubala

Masters Theses

Many works of art and literature exploring the theme of love focus on trying to define what love is; in contrast, this thesis dives deeper into defining what love is not, specifically focusing on the relationship between love and sacrifice. This thesis argues that love is not the same as sacrifice because a true sacrifice requires that love is already present prior to the sacrifice being made. This thesis will compare those who perform true sacrifices to those who perform sacrifices for their own personal gain by exploring grandiose narcissistic characters who perform (or attempt to perform) sacrifices without love …

Comparing Nurse Well-Being Across The Career Trajectory: An Analysis Of The Healthynurse Survey, Alison F. Cuccia

Creating Healthy Work Environments (CHWE)

Background: Nurses face persistent challenges in maintain well-being (Lönnqvist et al., 2025; Priano et al., 2018), which may contribute to the nurse staffing crisis. This analysis examines differences in well-being among nurses in different stages of their career trajectory.

Methods: Data from the HealthyNurse survey collected June 2024-May 2025 were examined (n=5006). Outcomes included fatigue, anxiety, depression, social ability, and physical functioning, measured using Patient-Reported Outcome Measurement Information System short form scales. Moderate to vigorous physical activity (MVPA, minutes/week), days of strength training per week, the Healthy Eating Index, and BMI were also measured and used as outcomes. …

Barks And Beans: A Place To Enjoy Two Things You Love, Erika Davis

Honors Projects

This project explores the necessary steps that need to be taken in order to have a successful and impactful pet cafe. "Barks and Beans" is a pet cafe created to enhance the community and benefit societies mental health and social wellbeing while operating as a successful business. This project is guided by the research questions "How does integrating dogs into a coffee shop environment influence factors such as customer attraction, retention, and overall brand identity?” and “What impact do dogs in a coffee shop have on a customer's emotional/mental well-being, satisfaction of experience, and likelihood of returning?”. Given the research …

Daily Eastern News: April 29, 2026, Eastern Illinois University

Daily Eastern News: 2025-2026

No abstract provided.

Objective, April L. Startzel

Student Projects

This thesis presents a body of paintings that explore the tension between lived experience, memory, and digitally constructed identity. Through layered narrative compositions, the work examines how individuals navigate and internalize multiple versions of themselves within an increasingly image-driven and digitally mediated world. Familiar objects, childhood references, and symbolic imagery serve as accessible entry points, while distortions in scale, composition, and material disrupt immediate recognition and invite active interpretation.

By integrating vivid color, dense compositions, and tactile elements such as polymer clay, the paintings emphasize the contrast between physical materiality and the flatness of digital screens. The recurring square format …

Young Bay Staters Report Considerably Lower Mental Health, Higher Stress Than Older Mass Residents 4/29/2026, Unh Survey Center

All UNH Survey Center Polls

Seven in ten Massachusetts residents rate their mental health as very good or good but a quarter say that their mental health has declined over the past 12 months. Three in eight report feeling bothered by feeling nervous, anxious, or on edge at least several days in the past two weeks and a quarter have felt that they lack companionship at least several days in that time. A quarter of Bay Staters report high levels of stress, with politics, work, international news, and household finances the most common contributors to daily stress. Massachusetts residents report most often dealing with stress …

Communication Strategies To Support Collections And Budget Management, Evan Rusch, Heidi J. Southworth, Nat Gustafson-Sundell, Lisa Baures, Daardi Mixon, Joe Holtermann

Library Services Publications

As budget management grows more challenging, we will need to communicate as successfully as possible to achieve the best possible outcomes. Communication with departments and administration about budget management and related changes to collections can be crucial to maintain constructive relationships and to improve cooperative planning. Academic libraries often rely on librarian liaisons to communicate directly with departments, but additional communication efforts are sometimes pursued. Our library has recently focused on collections communication across a range of projects and audiences. These projects have included a budget reduction plan and major print deselection project, as well as ongoing, prospective budget management. …

April 29, 2026 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

A Case Of Pembrolizumab Associated Sjs/Ten Spectrum Reaction, Lauryn Orsillo, Do, Alex Zhu, Md, Linh Tang Taylor, Md

Books, Presentations, Posters, Etc.

Introduction: Immune checkpoint inhibitors (ICIs), such as pembrolizumab, are becoming increasingly more common.1 They are associated with a variety of cutaneous immune-related adverse events which can range from drug eruptions to life-threatening Stevens–Johnson syndrome (SJS)/ toxic epidermal necrolysis (TEN) spectrum reactions.2 As use of these ICIs and PD1 inhibitors expands, the incidence of severe dermatologic toxicity can be expected to rise. Early recognition is critical, as SJS/TEN spectrum reactions carry substantial morbidity and mortality compared with drug eruptions. Case report: An 80-year-old female with a history of triple-negative breast cancer on pembrolizumab presented to the ED for evaluation of a …

Puzzling Papules: Uncovering The Etiology Of A Rash In A Returning Traveler, Lisa Stampke, Md, Shahana Baig-Lewis, Md

Books, Presentations, Posters, Etc.

Introduction: There are an estimated 1.8 billion people that travel internationally every year [1]. Approximately 22-64% of those acquire an infectious disease during or after returning home that is not endemic to their home country [1]. This is especially concerning in our current political climate and declining vaccination rates in the United States which places more patients at risk for preventable diseases [2]. These factors present a unique challenge in diagnosing and treating a symptomatic returning traveler. Case Description: A 25-year-old incompletely vaccinated male returned from Kenya after volunteering for 5-weeks in a rural hospital. He was in his usual …

Eosinophilic Fasciitis Masquerading As Myositis: A Diagnostic Challenge, Jennifer L. Wong, Do, Elizabeth S. Ballner, Do, Mary Elizabeth Swift-Taylor

Books, Presentations, Posters, Etc.

Introduction: Eosinophilic fasciitis (EF), or Shulman’s disease, is a rare disorder of unknown etiology and poorly understood pathogenesis. It is characterized by fibroblast activation and interleukin-driven eosinophilia. Early clinical features include limb or trunk erythema, non-pitting edema, and progressive fascial thickening, often producing an “orange peel” appearance. Eosinophilia is a prominent laboratory finding in the early phase, but diagnosis often requires a full-thickness skin-to-muscle biopsy. Systemic corticosteroids are first-line therapy, with methotrexate as the steroid -sparing agent for refractory disease. We present a unique and diagnostically challenging case of EF confirmed by histopathology. Case Presentation: A 56-year-old man presented with …

Extracorporeal Membrane Oxygenation (Ecmo) In Acute Chest Syndrome, Natalie Bolton, Md, Omar Pandhair

Books, Presentations, Posters, Etc.

Introduction: Acute chest syndrome (ACS) is a severe complication of sickle cell disease. Rarely, it may progress to acute respiratory distress syndrome (ARDS). Inability to oxygenate despite mechanical ventilation necessitates consideration of extracorporeal membrane oxygenation (ECMO). Case Summary: A 31-year-old man with sickle cell disease presented with low back pain similar to prior pain crises. Vital signs were normal, and his hemoglobin level was 10.2 g/dL, with a reticulocyte index of 0.05. He was admitted for pain control and rehydration. That night, he developed fever, tachypnea, and hypoxemia with imaging showing a right lower lobe infiltrate, consistent with ACS. He …

Spur Cell Anemia: A Crucial Unanticipated Anemia In Critical Care, Jobe Ashby

Books, Presentations, Posters, Etc.

INTRODUCTION: Spur Cell Anemia (SCA) is a rare underrecognized non-autoimmune hemolytic anemia occurring in severe liver disease with prognostic implications. Since the 1980s there have been only a few dozen case reports and clinical images concerning SCA. We present a case of a young man managed in the ICU with multiorgan failure and a masked diagnosis of SCA. DESCRIPTION: A 33-year-old man was found down and presented to the ICU with hematemesis and hemorrhagic shock. He required massive transfusion for bleeding esophageal varices that were later banded and an expanding thigh hematoma. He was diagnosed with alcohol induced liver cirrhosis …

Automated, Modular, Agentless Adversarial Emulation In Cloud Environments For Higher Education And Student Training, Doc Harley

Senior Honors Theses

Currently, the leading technologies in the market of adversarial emulation are MITRE Caldera, Atomic Red Team by IBM, and multiple proprietary products that come with support packages for different vendors like AttackIQ, Cymulate, SafeBreach, and many more. While it is clear that much work has been done in the broad category of adversarial emulation, when it comes to open source solutions, there are no agentless options with built in automation and modularity that have good support for cloud environments. Agentless adversarial emulation provides a unique advantage in that it can be both simpler and a better representation of the true …

Changing Employee Motivation From Obligation To Opportunity: Increasing Intrinsic Motivation In Non-Profit Organizations, Evelyn L. Williams

Senior Honors Theses

Motivation is a key driver behind tasks within the workforce. Harnessing employee motivation increases productivity, employee retention, efficiency, and output quality. Non-profit organizations, however, are often unable to devote resources to externally increasing motivation. This study presents a motivational model that is built from three motivation theories: Maslow’s Hierarchy of Needs, Herzberg’s Two Factor Theory, and Self-Determination theory. By incorporating principles from these theories this model helps organizations internalize and increase the effectiveness of their employees’ motivation through increasing the autonomy, competence, and relationality felt by each employee. The six tenets of the REWARD model give non-profit organizations a framework …

Lebesgue’S Theory Of Integration: An Introduction To Modern Integration Theory, Nathanael C. Krug

Senior Honors Theses

The depth and richness of integration theory far surpasses the introductory material presented in an elementary calculus classroom. The work of Bernhard Riemann and Henri Lebesgue demonstrates just a small sample of the richness of the field of analysis. In formulating and contrasting the Riemann and Lebesgue integrals, students can gain an enriched and well-rounded introduction to integration theory. This not only deepens understanding and love for previously learned material, but also enables further study within the fields of analysis and measure theory. An introductory primer to integration theory equips students with the tools needed to continue their exploration of …

Positive Factors Of Resilience In Marginalized Families, Amanda K. Rigsby

Doctoral Dissertations and Projects

The current study examined underexplored factors of resilience that help individuals overcome trauma. The study gathered insights from individuals in marginalized communities through semi-structured interviews and collected qualitative data for thematic analysis from 15 participants. The study identified polyvictimized individuals’ perspectives on (a) resilience, (b) regulation, (c) sense of purpose, and (d) mindfulness. Exploring the relationship between these areas could broaden our understanding and, in turn, inform targeted interventions through further studies. This study collected qualitative data through semi-structured interviews with individuals in the Appalachian region. The Resilience Portfolio Model has been used in research to identify mindfulness, regulation, sense …

The Impact Of Covid-19 On Playwork: Five Years On, Pete King

International Journal of Playwork Practice

In 2020, at the start of the March 2020 COVID-19 lockdown in the United Kingdom, a study was undertaken with 23 participants exploring the impact this may have on playwork and playwork practice.  That project started an 18-month longitudinal study between March 2020 and September 2022.  COVID-19 was five years ago, and this final study aimed to explore the current impact on playwork and playwork practice.  In total, 8 interviews were undertaken, and the results constructed 4 main themes regarding the continuing effects of COVID-19: 1) Community Engagement, 2) Emotional Regulation, 3) Outdoors, and 4) Health and Safety.  The findings …

Well-Being For Novice Nurses With The Powerful Feeling Of Belonging Through Mentorship, Shelli Anne Marie Chernesky, Natalie Bermudez, Diane Kramer

Creating Healthy Work Environments (CHWE)

Nursing is a known profession to help others by providing an environment of healing that includes elements of physical and psychological comfort. Our project looks at the importance of belonging as a form of supportive protection for the acute care novice nurse by using mentorship to help navigate the everchanging clinical environment. Mentoring has a direct correlation with belonging for nurses, being part of something with shared goals. Mentorship supports professional development while endorsing career pathway direction. Demanding clinical environments increase nursing responsibilities. Therefore, healthy work environments can be compromised and produce physical fatigue and mixed feelings leading to decreased …