Digital Commons Network^™

Low Elevation Coastal Zone (Lecz) Population Social Vulnerability And Risk: A Spatial Analysis Based On The 2015-16 National Family Health Survey (Nfhs-4) Of India, Paradorn Wongchanapai

Dissertations, Theses, and Capstone Projects

Background & Problem Statement:

This study assessed social vulnerability and risk to hydroclimate hazards of Indian urban and rural populations in the Low Elevation Coastal Zone (LECZ), a contiguous coastal area with elevations less than 10 meters. The LECZ is considered an at-risk area as hydroclimate hazards tend to be heightened. Moreover, being the most populous country in the world, any hydroclimate hazards that hit the LECZ would disproportionately impact a large number of Indian populations. Understanding the social vulnerability and risk of the LECZ populations can help mitigate and prevent potential adverse outcomes for the populations.

Importantly, this study …

‘The Power Of Three Will Set Us Free': Witchy Womanist Readings Of Toni Morrison’S Sula, Opal Palmer Adisa’S It Begins With Tears, And Migdalia Cruz’S The Have-Little And Miriam’S Flowers, Anamaría Flores

Dissertations, Theses, and Capstone Projects

Witchy womanism is a critical methodology for reading, teaching, and writing about literature in order to generate emancipatory knowledge, activate Queer, Black, and Indigenous consciousnesses, contribute to 21^st century women’s, Black, and Indigenous liberation movements, and foster (re)connections to ancestral rituals and knowledge. Born at the intersections of Black Studies, BIPOC Queer and Gender Studies, Caribbean Studies, English, Hip-Hop Studies and Latinx Studies, “‘The Power of Three Will Set Us Free’: Witchy Womanist Readings of Toni Morrison's Sula, Opal Palmer Adisa's It Begins With Tears, and Migdalia Cruz's The Have-Little and Miriam's Flowers" is a multidisciplinary …

An Examination Of Factors Associated With Ipv Victimization, Ipv Disclosure, And Help-Seeking Among Partnered Sexual Minority Men: An Integrated Theoretical Approach, Stephen Bosco

Dissertations, Theses, and Capstone Projects

The emerging body of research illustrates that sexual minority cis men (SMM) in a relationship experience intimate partner violence (IPV) at rates comparable to those reported by cis women in a heterosexual relationship. Although research on IPV in male relationships has increased, it is a phenomenon that remains considerably understudied compared to research examining IPV in a heterosexual relationship. Despite comparable rates of IPV victimization, SMM are less likely to disclose and use informal and formal support services compared to heterosexual women. To conceptualize and understand challenges to disclosure and help-seeking as well as identify facets to develop relevant and …

The Effect Of Alpha Binaural Beats On Virtual Reality Experiences, Andronikki C. Gerohristodoulos

Dissertations, Theses, and Capstone Projects

Visually induced motion sickness (VIMS), a subset of motion sickness, has been a long-term obstacle preventing comfortable experiences in virtual reality (VR). There is a growing body of research showing that binaural beats (BBs) have been effective to influence aspects of cognition. The goal of this experiment was to investigate the possible effects of attending to BBs and any changes to the severity of VIMS symptoms following immersion in a virtual reality environment (VRE). To validate our hypothesis a repeated-measures, between-subjects experiment was designed (n=16) and an alpha (10Hz) frequency BB and a control audio were created. Participants were split …

The Complete Sight And Sound Greatest Films Of All Time Database, Katie Donia

Dissertations, Theses, and Capstone Projects

Once every ten years, Sight and Sound, a film magazine produced by the British Film Institute (BFI), conducts an international poll of critics and film journalists to determine the “Greatest Films of All Time.” The first poll was conducted in 1952, and ten years later the BFI decided to make their poll decennial, allowing for the list to change and thus to demonstrate how time, changing opinion, and the continuous creation of new films change the film canon. However, despite the opportunity for long-term analysis, there is not an easy way online to see how a film’s ranking has changed …

The Biology Of Hope: Inflammatory And Neuroendocrine Profiles In Ovarian Cancer Patients, Susan K Lutgendorf, Rachel M Telles, Brendan Whitney, Premal H Thaker, George M Slavich, Frank J Penedo, Steven W Cole, Anil K Sood, Benjamin W Corn

Faculty, Staff and Student Publications

INTRODUCTION: Although the concept of hope is highly relevant for cancer patients, little is known about its association with cancer-relevant biomarkers. Here we examined how hope was related to diurnal cortisol and interleukin-6 (IL-6), a pro-inflammatory cytokine previously associated with tumor biology and survival in ovarian cancer. Secondly, we examined whether hope and hopelessness are distinctly associated with these biomarkers.

METHOD: Participants were 292 high-grade ovarian cancer patients who completed surveys and provided saliva samples 4x/daily for 3 days pre-surgery to assess diurnal cortisol. Blood (pre-surgery) and ascites were assessed for IL-6. Hope and hopelessness were assessed using standardized survey …

Pluripotency Of A Founding Field: Rebranding Developmental Biology, Crystal D Rogers, Chris Amemiya, Swathi Arur, Leslie Babonis, Michael Barresi, Richard Behringer, Dominique Bergmann, Ben Blackman, C Titus Brown, Bill Browne, Jasmin Camacho, Chiswili Yves Chabu, Ida Chow, Ondine Cleaver, Jonah Cool, Megan Y Dennis, Alexandra Jazz Dickinson, Stefano Di Talia, Margaret Frank, Stewart Gillmor, Eric S Haag, Iswar Hariharan, Richard Harland, Aman Husbands, Loydie Jerome-Majewska, Kristen Koenig, Carole Labonne, Michael Layden, Chris Lowe, Madhav Mani, Megan Martik, Katelyn Mckown, Cecilia Moens, Christian Mosimann, Joyce Onyenedum, Robert Reed, Ajna Rivera, Dan Rokhsar, Loic Royer, Flora Rutaganira, Rachel Shahan, Neelima Sinha, Billie Swalla, Jaimie M Van Norman, Daniel E Wagner, Athula Wikramanayake, Sophia Zebell, Siobhán M Brady

Faculty, Staff and Student Publications

The field of developmental biology has declined in prominence in recent decades, with off-shoots from the field becoming more fashionable and highly funded. This has created inequity in discovery and opportunity, partly due to the perception that the field is antiquated or not cutting edge. A 'think tank' of scientists from multiple developmental biology-related disciplines came together to define specific challenges in the field that may have inhibited innovation, and to provide tangible solutions to some of the issues facing developmental biology. The community suggestions include a call to the community to help 'rebrand' the field, alongside proposals for additional …

Deep Learning-Based Automatic Segmentation Of Cardiac Substructures For Lung Cancers, Xinru Chen, Raymond P Mumme, Kelsey L Corrigan, Yuki Mukai-Sasaki, Efstratios Koutroumpakis, Callistus M Nguyen, Kai Huang, Cenji Yu, Ting Xu, Aji Daniel, Peter A Balter, Xiaodong Zhang, Joshua S Niedzielski, Sanjay S Shete, Anita Deswal, Laurence E Court, Zhongxing Liao, Jinzhong Yang

Faculty, Staff and Student Publications

Purpose: Accurate and comprehensive segmentation of cardiac substructures is crucial for minimizing the risk of radiation-induced heart disease in lung cancer radiotherapy. We sought to develop and validate deep learning-based auto-segmentation models for cardiac substructures.

Materials and methods: Nineteen cardiac substructures (whole heart, 4 heart chambers, 6 great vessels, 4 valves, and 4 coronary arteries) in 100 patients treated for non-small cell lung cancer were manually delineated by two radiation oncologists. The valves and coronary arteries were delineated as planning risk volumes. An nnU-Net auto-segmentation model was trained, validated, and tested on this dataset with a split ratio of 75:5:20. …

Mediators Of Necroptosis: From Cell Death To Metabolic Regulation, Xiaoqin Wu, Laura E Nagy, Jérémie Gautheron

Faculty, Staff and Student Publications

Necroptosis, a programmed cell death mechanism distinct from apoptosis, has garnered attention for its role in various pathological conditions. While initially recognized for its involvement in cell death, recent research has revealed that key necroptotic mediators, including receptor-interacting protein kinases (RIPKs) and mixed lineage kinase domain-like protein (MLKL), possess additional functions that go beyond inducing cell demise. These functions encompass influencing critical aspects of metabolic regulation, such as energy metabolism, glucose homeostasis, and lipid metabolism. Dysregulated necroptosis has been implicated in metabolic diseases, including obesity, diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD), contributing to chronic …

Txnrd1 Drives The Innate Immune Response In Senescent Cells With Implications For Age-Associated Inflammation, Xue Hao, Bo Zhao, Martina Towers, Liping Liao, Edgar Luzete Monteiro, Christina Freeman, Hsin-Yao Tang, Aaron Havas, Andrew V Kossenkov, Shelley L Berger, Peter D Adams, David W Speicher, David Schultz, Ronen Marmorstein, Kenneth S Zaret, Rugang Zhang

Faculty, Staff and Student Publications

Sterile inflammation, also known as 'inflammaging', is a hallmark of tissue aging. Cellular senescence contributes to tissue aging, in part, through the secretion of proinflammatory factors collectively known as the senescence-associated secretory phenotype (SASP). The genetic variability of thioredoxin reductase 1 (TXNRD1) is associated with aging and age-associated phenotypes such as late-life survival, activity of daily living and physical performance in old age. TXNRD1's role in regulating tissue aging has been attributed to its enzymatic role in cellular redox regulation. Here, we show that TXNRD1 drives the SASP and inflammaging through the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) …

Minimal Information For Studies Of Extracellular Vesicles (Misev2023): From Basic To Advanced Approaches, Joshua A Welsh, Deborah C I Goberdhan, Lorraine O'Driscoll, Edit I Buzas, Cherie Blenkiron, Houjian Cai, Tom A P Driedonks, Uta Erdbrügger, Juan M Falcon-Perez, Qing-Ling Fu, Andrew F Hill, Metka Lenassi, Sai Kiang Lim, Mỹ G Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M Bridges, Marco Brucale, Dylan Burger, Randy P Carney, Emanuele Cocucci, Rossella Crescitelli, Edveena Hanser, Adrian L Harris, Norman J Haughey, An Hendrix, Alexander R Ivanov, Tijana Jovanovic-Talisman, Nicole A Kruh-Garcia, Vroniqa Ku'ulei-Lyn Faustino, Diego Kyburz, Cecilia Lässer, Kathleen M Lennon, Jan Lötvall, Adam L Maddox, Elena S Martens-Uzunova, Rachel R Mizenko, Lauren A Newman, Andrea Ridolfi, Eva Rohde, Tatu Rojalin, Andrew Rowland, Andras Saftics, Ursula S Sandau, Julie A Saugstad, Faezeh Shekari, Simon Swift, Dmitry Ter-Ovanesyan, Juan P Tosar, Zivile Useckaite, Francesco Valle, Zoltan Varga, Edwin Van Der Pol, Martijn J C Van Herwijnen, Marca H M Wauben, Ann M Wehman, Sarah Williams, Andrea Zendrini, Alan J Zimmerman, Clotilde Théry, Kenneth W Witwer

Faculty, Staff and Student Publications

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional …

Neurologic Morbidity And Functional Independence In Adult Survivors Of Childhood Cancer, Stefanie C Vuotto, Mingjuan Wang, M Fatih Okcu, Daniel C Bowers, Nicole J Ullrich, Chenghong Li, Rebecca M Howell, Todd M Gibson, Wendy M Leisenring, Kevin C Oeffinger, Leslie L Robison, Gregory T Armstrong, Kevin R Krull, Tara M Brinkman

Faculty, Staff and Student Publications

OBJECTIVE: To examine associations between neurologic late effects and attainment of independence in adult survivors of childhood cancer treated with central nervous system (CNS)-directed therapies.

METHODS: A total of 7881 survivors treated with cranial radiation therapy (n = 4051; CRT) and/or intrathecal methotrexate (n = 4193; IT MTX) ([CNS-treated]; median age [range] = 25.5 years [18-48]; time since diagnosis = 17.7 years [6.8-30.2]) and 8039 without CNS-directed therapy reported neurologic conditions including stroke, seizure, neurosensory deficits, focal neurologic dysfunction, and migraines/severe headaches. Functional independence was assessed using latent class analysis with multiple indicators (independent living, assistance with routine and personal …

Circulating Tumor Dna And Radiological Tumor Volume Identify Patients At Risk For Relapse With Resected, Early-Stage Non-Small-Cell Lung Cancer, H T Tran, S Heeke, S Sujit, N Vokes, J Zhang, V K Lam, S G Swisher, M C B Godoy, T Cascone, B Sepesi, D L Gibbons, J Wu, J V Heymach

Faculty, Staff and Student Publications

Background: Predicting relapse and overall survival (OS) in early-stage non-small-cell lung cancer (NSCLC) patients remains challenging. Therefore, we hypothesized that detection of circulating tumor DNA (ctDNA) can identify patients with increased risk of relapse and that integrating radiological tumor volume measurement along with ctDNA detectability improves prediction of outcome.

Patients and methods: We analyzed 366 serial plasma samples from 85 patients who underwent surgical resections and assessed ctDNA using a next-generation sequencing liquid biopsy assay, and measured tumor volume using a computed tomography-based three-dimensional annotation.

Results: Our results showed that patients with detectable ctDNA at baseline or after treatment and …

Experiences Of Patients With Peritoneal Carcinomatosis-Related Complex Care Needs And Their Caregivers, Rachel A Pozzar, Jaclyn A Wall, Anna Tavormina, Embree Thompson, Andrea C Enzinger, Susana Campos, Alexi A Wright

Faculty, Staff and Student Publications

Background: Patients with peritoneal carcinomatosis (PC) frequently undergo palliative procedures, yet these patients and their caregivers report being unprepared to manage ostomies, drains, and other complex care needs at home. The purpose of this study was to characterize the unique needs of these patients and their caregivers during care transitions.

Methods: Patients completed measures of health status and advance care planning, caregivers completed measures of preparedness and burden, and all participants completed measures of depression and anxiety. Participants detailed their experiences in individual, semi-structured interviews. We analyzed data using descriptive statistics and conventional content analysis.

Results: Sixty-one patients and 39 …

Intraoperative Language Mapping Guided By Real-Time Visualization Of Gamma Band Modulation Electrocorticograms: Case Report And Proof Of Concept, Kyle R Noll, Priscella Asman, Israt Tasnim, Matthew Hall, Katherine Connelly, Chibawanye Ene, Roxana M Grasu, Ho-Ling Liu, Vinodh A Kumar, Matthew Muir, Sarah Prinsloo, Hayley Michener, Jeffrey S Wefel, Nuri F Ince, Sujit S Prabhu

Faculty, Staff and Student Publications

BACKGROUND: Electrocorticography (ECoG) language mapping is often performed extraoperatively, frequently involves offline processing, and relationships with direct cortical stimulation (DCS) remain variable. We sought to determine the feasibility and preliminary utility of an intraoperative language mapping approach guided by real-time visualization of electrocorticograms.

METHODS: A patient with astrocytoma underwent awake craniotomy with intraoperative language mapping, utilizing a dual iPad stimulus presentation system coupled to a real-time neural signal processing platform capable of both ECoG recording and delivery of DCS. Gamma band modulations in response to 4 language tasks at each electrode were visualized in real-time. Next, DCS was conducted for …

New Algorithmic Support For The Fundamental Theorem Of Algebra, Vitaly Zaderman

Dissertations, Theses, and Capstone Projects

Univariate polynomial root-finding is a venerated subjects of Mathematics and Computational Mathematics studied for four millenia. In 1924 Herman Weyl published a seminal root-finder and called it an algorithmic proof of the Fundamental Theorem of Algebra. Steve Smale in 1981 and Arnold Schonhage in 1982 proposed to classify such algorithmic proofs in terms of their computational complexity. This prompted extensive research in 1980s and 1990s, culminated in a divide-and-conquer polynomial root-finder by Victor Pan at ACM STOC 1995, which used a near optimal number of bit-operations. The algorithm approximates all roots of a polynomial p almost as fast as one …

The Early Late Miocene Cessation Of Deep And Intermediate Water Circulation Through The Central American Seaway, Benjamin Stanley Kwiatkowski

Dissertations, Theses, and Capstone Projects

The state of the middle late Miocene global ocean circulations which regulated climate and affected deep ocean chemical environments were impacted by geographic changes. During the Miocene, cirum-equatorial circulations slowly decreased, which included through the seaway between the Americas called the Central American Seaway (CAS). Its shoaling and ultimate closing led to the onset of modern day oceanic circulation as characterized by the global thermohaline circulation. However, this seaway has a long hotly debated history concerning the timing of its restriction and shallowing owing in part to the shifting of tectonic plates.

The goal of this research focuses on investigating …

Fashion, Freedom, And Feminism: The Transcendent Work Of Rosa Genoni And Her "Tanagra Dress" Reimagined, Christina Trupiano

Dissertations, Theses, and Capstone Projects

The fashion industry itself is broad in scope and dependent upon numerous sub-industries to produce its garments. It is heavily dependent upon machinery of all kinds, yet unlike many industries today, it is still also largely reliant on manual labor, specifically minority women labor. This dependance upon manual labor correlates with its long history of worker exploitation and sweated labor. The concentration of exploitative labor practices in the fashion industry have made it a focal point in the ongoing struggle between workers and the downward pressure capitalism and industrialization placed on worker compensation, quality of life and job security.

This …

Teaching In The “Home Language” Is Not Enough: Navigating Spanish Raciolinguistic Ideologies In A Dual Language Bilingual Program, Gladys Yacely Aponte

Dissertations, Theses, and Capstone Projects

This ethnographic case study examines how fourth graders in a New York City Spanish/English dual language bilingual public school navigate hegemonic language ideologies about Spanish. Drawing on the scholarship of raciolinguistic ideologies—those that position the language practices of people of color as inherently deficient (Flores & Rosa, 2015), I analyze the discourse of seven Kiskeyanx students to examine how they navigate the widespread raciolinguistic marginalization of Kiskeyanxs— a demographic that is racialized as more Black than other Spanish-speaking groups.

As a first-generation Kiskeyana-New Yorker, a bilingual teacher educator and researcher, and a former dual language bilingual public-school teacher, it …

Socially Safe On Smartphones: How Smartphone Use Reduces Social Risk Taking, Diogo Koch Alves

Dissertations, Theses, and Capstone Projects

Consumers are often faced with decisions that carry a degree of social risk, with uncertain outcomes that could impact their social standing. Examples include choosing the ideal outfit to wear to an upcoming party or selecting a gift to give to a friend. Given the prevalence of smartphones in consumer decision making, I investigate the effect of smartphone use on social risk taking. Across seven studies, I find that smartphone use, relative to the use of other devices, results in a lower propensity to make socially risky decisions. I propose that smartphone use, by increasing the salience of one’s social …

A Municipal Modernity: Women, Architecture, And Public Health In Working-Class New York, 1913–1950, Jessica Fletcher

Dissertations, Theses, and Capstone Projects

“A Municipal Modernity” is the first study to analyze the architectural history of the district health centers in New York City that women reformers and their allies founded to address poor health in working-class communities. It reveals that women’s philanthropic adaptive re-use was foundational to the architecture of the public health care in New York and led to a program of municipal district health centers. Philanthropic reformers adapted buildings in the 1910s and 1920s to provide affordable health care for low-income women and children in European immigrant and Black neighborhoods. During the New Deal, municipal officials followed the example set …

Using Leaf Spectra To Elucidate The Taxonomy And Ecology Of Living And Dried Plants, Natalia L. Quinteros Casaverde

Dissertations, Theses, and Capstone Projects

Identifying plants and understanding of changes in plant communities are crucial to the conservation and management of nature. The shortwave spectral reflectance of leaves is a promising tool for rapidly identifying species at different taxonomic ranks and predicting important plant functional traits. However, the spectral reflectance of leaves changes in response to biotic and abiotic conditions.

The aim of this dissertation is to investigate the potential of shortwave spectral reflectance to investigate (Chapter 1) how its variation affects the accuracy of methods used to predict plant taxonomies and what environmental factors most influence biophysically predicted traits, (Chapter 2) what are …

Power And The Press: Reimagining The World By Producing Information Together, Jen Hoyer

Dissertations, Theses, and Capstone Projects

This study of three collectively-organized activist printing projects examines how information production is a strategy for communities to reimagine and reconfigure oppressive power structures. I consider the High School Student Union and their newspaper, the High School Free Press; the women’s collective that took over RAT Subterranean News; and WIMP, a radical printing collective that broke away from the New York City Students for a Democratic Society chapter and supported a variety of progressive movements in New York City in the late 1960s and early 1970s. This research examines how dissatisfaction with oppressive power structures leads individuals to build collective …

Cinema And Ritual: Decolonial Feminist Approaches To Image-Making In The Americas And The Caribbean, Natalie M. Erazo

Dissertations, Theses, and Capstone Projects

This thesis project is composed of an open-access syllabus hosted on a CUNY commons site, as well as a paper that examines various films and texts responding to the theme of cinema and ritual. Referenced films will focus on ritual as a decolonial feminist methodological framework, rooted primarily in Afro-descended and Indigenous cosmovisions within Latin America and the Caribbean. From a dance ritual spell warding off U.S. imperialism in present-day Puerto Rico, to a poetic visual eulogy for murdered women in rural Mexico, to a community prayer to Yemaya bringing relief for water scarcity in Cuba to a cautionary tale …

Stereospecific Cross-Coupling Reactions Of Enantioenriched Secondary Alkyltricyclohexyltin Nucleophiles, Meruyert Binayeva

Dissertations, Theses, and Capstone Projects

Transition metal-catalyzed cross-coupling reactions have evolved into a remarkable instrument for the formation of new bonds, and have significantly impacted how we approach to access complex organic molecules. Palladium is currently one of the most popular elements for catalytic applications due to its ability to facilitate powerful carbon-carbon and carbon-heteroatom couplings. Traditional Pd-catalyzed cross-coupling reactions have primarily concentrated on C(sp2)-C(sp2) cross-couplings, yielding planar products. Considering the use of C(sp3) nucleophiles would offer a viable control of the three dimensional arrangement in molecules. Herein, the first chapter details the history and development of Pd-catalyzed Stille cross-coupling reactions. The use of configurationally …

The Construction Of Victimhood In Human Trafficking Intervention Courts, Lauren Moton

Dissertations, Theses, and Capstone Projects

Human trafficking intervention courts (HTICs), specialty courts in the US designed to connect trafficking victims to services when they are arrested, require defendants to identify as victims of human trafficking in order to qualify for HTICs' services and other social supports. However, some defendants may be autonomously trading sex, thereby raising questions about the meaning of the term "victim" within HTICs. Therefore, my study asks the following: a) at the institutional level, how do HTICs’ rules, norms, procedures, and stakeholders implement and give meaning to the “victim” label, and why?; and b) at the individual level, how do people who …

From The Outside Looking In: Transmasculine Narrative Identity, Experiences, And Larger Narratives On Social Media, Micah Roldan

Dissertations, Theses, and Capstone Projects

Narrative identity development is an essential process in how individuals perceive themselves and the world around them. Often, narrative identity is studied in cisgender heterosexual individuals and applied to others without the acknowledgment of individuals that fall outside of these categories. Drawing upon existing literature and autoethnography, this thesis aims to meaningfully bridge this gap by studying the narrative identity development of transmasculine individuals through the lens of social media. This thesis proposes that the use of social media to share gender transition journeys has created a new digital trans and queer narrative for users and viewers. This narrative is …

Interracial Instagram: Depictions Of Interracial Couples On Instagram, Christie Sillo

Dissertations, Theses, and Capstone Projects

This dissertation examines depictions of interracial romantic relationships on Instagram, a popular photo- and video-sharing social networking site. Social networking sites like Instagram, whereby users connect with each other by creating, sharing, and consuming content, are prime sites for sociological study because ideas are constantly being (re)made on them. On Instagram, meaning-making is mainly done through the construction of a profile and the posting of images and/or videos. Using a mixed-methods research design of hashtag analysis, digital ethnography, discourse and image analysis, I critically analyze Instagram profiles that depict interracial romantic relationships. In doing so, I develop a contemporary, social …

Values In Evidence-Based Policy: Bridging Socio-Political, Moral, And Epistemic Domains, Karyna Pryiomka

Dissertations, Theses, and Capstone Projects

Values constitute an inescapable constant of any policymaking or evidence-production process. In this dissertation I explore ways in which socio-political, moral, and epistemic values inform evidence production and use in public higher education policy. In “Chapter One: Introduction and Literature Review”, I provide a brief overview of evidence-based policy as a practice. I then discuss three major categories of values, focusing on higher education examples whenever possible. Finally, I present the central study of this dissertation. The central question of my dissertation is In what ways do epistemic, socio-political, and moral values frame the production and deployment of evidence in …

The Role Of Glutamate In The Medial Prefrontal Cortex In The Acquistion And Expression Of Conditioned Approach, Rudolf Nisanov

Dissertations, Theses, and Capstone Projects

A series of experiments were conducted to assess the role of glutamatergic stimulation in the dorsal and ventral regions of the medial prefrontal cortex (mPFC) in both the acquisition and expression of reward-related learning using a Pavlovian conditioning paradigm, the conditioned-approach paradigm. Rats with surgically implanted cannulas were exposed to Pavlovian conditioning sessions that occurred on three alternative days (acquisition) or seven consecutive days (expression). These 60-min conditioning sessions consisted of 30 pairings of light (CS) and food pellets (US) presented under a random time schedule. After a two-day break, rats underwent a session with no CS or US and …