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How School Leaders Can Increase Teacher Satisfaction In A Rural Fringe High School In South Carolina, William T. Dyer Aug 2024

How School Leaders Can Increase Teacher Satisfaction In A Rural Fringe High School In South Carolina, William T. Dyer

All Dissertations

Unfilled teaching positions are rising in South Carolina, increasing year over year. To combat this problem of practice, I conducted an improvement science study to understand factors that impact teacher satisfaction levels aimed to raise teacher retention rates. The study aimed to allow teachers to identify areas that school administrators can target to positively affect teacher satisfaction levels. I created a change idea based on this teacher feedback to impact their retention decisions. As an educator, I have identified three major themes in this area. First, influence over their profession impacts teachers' decision to return to their position each year. …


Linear And Nonlinear Topology Optimization With Morphing Beam Networks, Andrew S. Montalbano Aug 2024

Linear And Nonlinear Topology Optimization With Morphing Beam Networks, Andrew S. Montalbano

All Dissertations

Topology optimization (TO) is an engineering design discipline dedicated to optimizing material distribution within a given domain. In traditional gradient-based topology optimization, the solid domain is discretized into small volumetric elements. Using finite element analysis (FEA) of the structure, the gradient of the objective function with respect to the design variables (the pseudo densities) is computed, and these design variables are updated iteratively until convergence is achieved. Although gradient-based TO methods are well-established, sensitivity analyses of objective functions and constraints can be both mathematically complex and computationally intensive. The nonconvex nature of most TO problems often complicates efficient convergence. Furthermore, …


Hybrid Physics-Infused Machine Learning Framework For Fault Diagnostics And Prognostics In Cyber-Physical System Of Diesel Engine, Shubhendu Kumar Singh Aug 2024

Hybrid Physics-Infused Machine Learning Framework For Fault Diagnostics And Prognostics In Cyber-Physical System Of Diesel Engine, Shubhendu Kumar Singh

All Dissertations

Fault diagnosis is required to ensure the safe operation of various equipment and enables real-time monitoring of associated components. As a result, the demand for new cognitive fault diagnosis algorithms is the need of the hour. Existing deep learning algorithms can detect, classify, and isolate faults. Still, most depend solely on data availability and do not incorporate the system's underlying physics into their prediction. Therefore, the results generated by these fault-detecting algorithms sometimes need to make more sense and deliver when tested in actual operating conditions.

Similar to diagnosis, the fault prognosis of diesel engines is paramount in numerous industries. …


Opportunities To Learn In Rural South Carolina Schools: Rurality, Place, And Passion, Grig Sawyer Aug 2024

Opportunities To Learn In Rural South Carolina Schools: Rurality, Place, And Passion, Grig Sawyer

All Dissertations

High school principals can change the status quo of the current iniquitous disparities in the education system between South Carolina’s rural high schools and their more populated and affluent suburban schools. Using a non-standard structure and the resources in their control, these school leaders can find solutions so schools can offer rural students advanced math and science programs. Yet, there is a paucity of studies examining how small rural school principals make advanced math and science courses available to their students, particularly in rural South Carolina. Thus, studies must examine how South Carolina school leaders successfully offer advanced math and …


Genomic Data Science Approaches For Understanding Human Diseases, Snehal Shah Aug 2024

Genomic Data Science Approaches For Understanding Human Diseases, Snehal Shah

All Dissertations

The intricate interplay of genetic predisposition, environmental influences, and lifestyle acts as the multifactorial landscape of diseases. Understanding this complexity presents a significant challenge. Molecular insights into disease mechanisms, particularly the interactions of DNA, RNA, and proteins with environmental and lifestyle factors, have revolutionized disease diagnosis, prognosis, and treatment. High-throughput technologies, such as next-generation sequencing, generate large amounts of molecular data, holding a wealth of knowledge. These datasets unveil the roles of genes and their interactions with various factors through analysis, shedding light on previously unknown molecular mechanisms underlying disease pathogenesis. Furthermore, they facilitate the discovery of biomarkers crucial for …


Essays On Retail Operations, Yao Chen Aug 2024

Essays On Retail Operations, Yao Chen

All Dissertations

This dissertation consists of three essays examining various aspects of retail operations. The first essay explores the strategic implementation of free in-store pickup services. Motivated by the rise of omni-channel strategies, it analytically models how a profit-maximizing retailer decides to adopt free ship-to-store services for online-exclusive products. The analysis reveals the effects on pricing, shipping fees, and customer behavior, as well as how these services attract foot traffic and boost in-store sales. Prescriptive models are provided to help retailers assess the potential value and customer response to ship-to-store services.

The second essay investigates the impact of negative environmental, social, and …


Preparing For Kindergarten: An In-Depth Look At The Lived Experiences Of Parents Preparing A Child For Kindergarten, Grace Bache-Wiig Aug 2024

Preparing For Kindergarten: An In-Depth Look At The Lived Experiences Of Parents Preparing A Child For Kindergarten, Grace Bache-Wiig

All Dissertations

The purpose of this multi-modal phenomenological study was to examine the lived experiences of parents preparing their first child for kindergarten and to evaluate the sources of information used to inform these experiences. Eight parents of rising kindergarteners were sampled for interviewing from preschool and homeschool settings in North Carolina. Semi-structured interviews were conducted to explore participant experiences and participants identified sources of information to be gathered for content analysis. The interview transcripts were analyzed using van Manen’s approach to identify units of meaning. Four major themes emerged from this study: emotions about kindergarten readiness, an emphasis on social and …


Relating Elasticity And Other Multiplicative Properties Among Orders In Number Fields And Related Rings, Grant Moles Aug 2024

Relating Elasticity And Other Multiplicative Properties Among Orders In Number Fields And Related Rings, Grant Moles

All Dissertations

This dissertation will explore factorization within orders in a number ring. By far the most well-understood of these orders are rings of algebraic integers. We will begin by examining how certain types of subrings may relate to the larger rings in which they are contained. We will then apply this knowledge, along with additional techniques, to determine how the elasticity in an order relates to the elasticity of the full ring of algebraic integers. Using many of the same strategies, we will develop a corresponding result in the rings of formal power series. Finally, we will explore a number of …


An Emergency Response System To Assist The Movement Of Vehicles During Emergency Operations In Urban Transportation Networks, Jamal Nahofti Kohneh Aug 2024

An Emergency Response System To Assist The Movement Of Vehicles During Emergency Operations In Urban Transportation Networks, Jamal Nahofti Kohneh

All Dissertations

Emergency responders need to arrive at the emergency scene as soon as possible, but operating vehicles under emergency conditions can pose a risk to both the responders and other road users, potentially resulting in crashes or delays in emergency operations. In this research, an emergency response system is proposed to assist emergency and non-emergency response vehicles (ERVs and non-ERVs) during emergency operations in a connected vehicle environment. This system collects the information from connected ERVs and non-ERVs, utilizes this information as inputs in the proposed models, and sends instruction messages back to vehicles. The proposed models provide the fastest ERV …


Gan With Skip Patch Discriminator For Biological Electron Microscopy Image Generation, Nishith Ranjon Roy Aug 2024

Gan With Skip Patch Discriminator For Biological Electron Microscopy Image Generation, Nishith Ranjon Roy

Graduate Theses and Dissertations

GAN models have been successfully used for image generation in various sections such as real-life objects like human faces, cars, animal faces, landscapes, etc. This work focuses on biological electron microscopy (EM) image generation. Unlike other real-life objects, biological EM images are obtained through electron microscopy techniques to study biological specimens. Electron microscopy offers high resolution and magnification capabilities, making it a powerful tool for visualizing biological structures at the nanoscale. However, using GAN models for biological EM image generation poses challenges due to the complex and unique arrangements of biological structures and the sparse and asymmetrical patterns in EM …


Facilitating Parental Scaffolding Of Joint Book Reading With Toddlers, Tiffany Pempek Rahl Aug 2024

Facilitating Parental Scaffolding Of Joint Book Reading With Toddlers, Tiffany Pempek Rahl

Dissertations, 2020-current

Developmental research confirms the importance of early parental language input for building children’s vocabulary and language skills (Hart & Risley, 1995). While reading with a caregiver is a common way for language input to occur, the approaches parents utilize often fail to capitalize on techniques for improving language and pre-literacy skills (Huebner & Meltzoff, 2005). The purpose of this study was to assess the effectiveness of embedding tips for scaffolding parent reading strategies into a children’s book. Thirty-eight parent-child dyads participated in a 2-week intervention. Families were randomly assigned to receive either a book with embedded tips (experimental condition) or …


Factors That Help And Hinder Experience Of Reflective Functioning In An Attachment-Based Intervention: An Enhanced Critical Incident Technique Analysis Of Parents’ Experiences, Shelly-Ann Peart James Aug 2024

Factors That Help And Hinder Experience Of Reflective Functioning In An Attachment-Based Intervention: An Enhanced Critical Incident Technique Analysis Of Parents’ Experiences, Shelly-Ann Peart James

Dissertations, 2020-current

This study explored parents’ experiences as it relates to their capacity to think about their child’s thinking and feeling, Parental Reflective Functioning (PRF), an attachment theory construct. PRF was explored in the context of an attachment-based intervention, the Secure Child Program (SCP), that focuses on children and their families. Parents’ voices were centered in this study through the employment of narrative research methodology, specifically, the Enhanced Critical Incident Technique. Participants consisted of seven parents within the SCP. A semi-structured interview developed for the study was informed by extant measures of PRF. Findings indicate helping and hindering categories with the vast …


Candida Albicans Farnesol Synthesis And Secretion, Daniel J. Gutzmann Aug 2024

Candida Albicans Farnesol Synthesis And Secretion, Daniel J. Gutzmann

School of Biological Sciences: Dissertations, Theses, and Student Research

Candida albicans is a polymorphic fungus and opportunistic commensal found primarily in the gastrointestinal and skin of healthy individuals. Several barriers prevent C. albicans from causing disease including a healthy immune system and microbiome. When these barriers become comprised, C. albicans can transition to a pathogen and disseminate through the intestinal mucosa leading to life-threatening bloodstream and invasive infections with mortality rates of up to 64%. Morphogenic plasticity is key to this transition and impacts virulence, adaptation to different host environments, and evasion of host immune responses. One regulator of morphogenesis is farnesol. Farnesol is a secondary metabolite of …


Cancer Care Terminology In African Languages, Hannah Simba, Miriam Mutebi, Moses Galukande, Yahya Mahamat-Saleh, Elom Aglago, Adamu Addissie, Lidya Genene Abebe, Justina Onwuka Aug 2024

Cancer Care Terminology In African Languages, Hannah Simba, Miriam Mutebi, Moses Galukande, Yahya Mahamat-Saleh, Elom Aglago, Adamu Addissie, Lidya Genene Abebe, Justina Onwuka

General Surgery, East Africa

Importance: Effective communication between patients and health care teams is essential in the health care setting for delivering optimal cancer care and increasing cancer awareness. While the significance of communication in health care is widely acknowledged, the topic is largely understudied within African settings.

Objective: To assess how the medical language of cancer and oncology translates into African languages and what these translations mean within their cultural context.

Design, etting, and participants: In this multinational survey study in Africa, health professionals, community health workers, researchers, and scientists involved in cancer care and research and traditional healers were invited to participate …


Training A Behavior Technician In The Implementation Of The System Of Least Prompts Using Behavioral Skills Training, Clara Wincheski Aug 2024

Training A Behavior Technician In The Implementation Of The System Of Least Prompts Using Behavioral Skills Training, Clara Wincheski

Masters Theses, 2020-current

The purpose of this study was to extend the literature base on behavioral skills training (BST) to detail its effects in assisting a behavior technician (BT) in acquisition of the skills necessary to implement a response prompting procedure, system of least prompts (SLP). This inquiry was guided by the following research questions: (1) What are the effects of BST on the acquisition of SLP across three behaviors of a BT? and (2) Does the BT accept this intervention as socially significant, and tangentially, does a Board Certified Behavior Analyst also find it to be socially significant within the context of …


Guiding The Management Of Acute Promyelocytic Leukemia: A Quality Improvement Project, Lauren Sheldon, Donna M. Tydings, Tara L. Sacco Aug 2024

Guiding The Management Of Acute Promyelocytic Leukemia: A Quality Improvement Project, Lauren Sheldon, Donna M. Tydings, Tara L. Sacco

Nursing Doctoral

Background: Despite successful treatment regimens and remission rates of greater than 90%, early death is a concern for patients with acute promyelocytic leukemia (APL). The challenges surrounding proper care for APL are centered on the low volume of patients, which limits healthcare professionals’ knowledge of disease management.

Objectives: The purpose of this project was to develop resources and present an educational module specific to managing patients newly diagnosed with APL. An intervention to evaluate bedside nurses’ knowledge of APL was implemented.

Methods: Thirty-four RNs were recruited for participation. A clinical practice guideline, an algorithm, and a fact sheet were developed …


Cubic Soft Ideals On B-Algebra For Solving Complex Problems: Trend Analysis, Proofs, Improvements, And Applications, Muhammad Saeed, Hafiz Inam Ul Haq, Mubashir Ali Aug 2024

Cubic Soft Ideals On B-Algebra For Solving Complex Problems: Trend Analysis, Proofs, Improvements, And Applications, Muhammad Saeed, Hafiz Inam Ul Haq, Mubashir Ali

Neutrosophic Systems with Applications

In this paper, we introduce the concepts of cubic soft (CS) algebra, CS o-subalgebra, and CS ideals within the framework of B-algebra. We provide comprehensive characterizations of these new structures, elucidating their unique properties and interrelationships. Specifically, we present detailed conditions under which a CS subalgebra can be classified as a closed CS ideal. Our analysis explores the intricate relationships among closed cubic soft ideals, cubic soft subalgebras, and cubic soft o-subalgebras. By doing so, we aim to provide a deeper understanding of how these structures interact and coexist within the broader context of B-algebra The findings offer significant insights …


Divergence Measures And Aggregation Operators For Single-Valued Neutrosophic Sets With Applications In Decision-Making Problems, Surender Singh, Sonam Sharma Aug 2024

Divergence Measures And Aggregation Operators For Single-Valued Neutrosophic Sets With Applications In Decision-Making Problems, Surender Singh, Sonam Sharma

Neutrosophic Systems with Applications

Single-valued neutrosophic sets (SVNSs) facilitate the representation of uncertain information more extensively than conventional methods. The study of divergence measures of SVNSs is important due to their applications in different areas like multi-criteria decision-making (MCDM), pattern recognition, cluster analysis, machine learning, etc., In this paper, we introduce a divergence measure for SVNSs. The suggested divergence measure is applied to cluster analysis for the classification of imprecise data. For establishing the reasonability and advantage of the suggested divergence measure in a clustering problem over the existing measures, a comparative assessment is also presented. Furthermore, we introduce, an inferior ratio method for …


The Growth Mindset Revolution, Paula Bibiana Garcia Cardona, Martha Isabel Tejada Sanchez, Martha Ramirez Aug 2024

The Growth Mindset Revolution, Paula Bibiana Garcia Cardona, Martha Isabel Tejada Sanchez, Martha Ramirez

GHEA21 Open Educational Resources

The Growth Mindset Revolution is a manual for educators designed to support the development of a growth mindset culture within the perspectives of Universal Design for Learning (UDL) and interculturality. As an in-service or pre-service educator in higher or technical education, one will find explanations, lesson plans, resources, videos, and podcasts with testimonials that will help you create pedagogical practices that encourage growth and development for your students. We invite you to use this guide as a reference in the field of teacher education and professional development and related areas, promoting a mindset transformation for a global network of educators.


How Teachers Perceive Teacher Leadership In A Massachusetts Urban Turnaround High School: A Concurrent Mixed-Methods Case Study, Matthew Lawrence Mccarthy Aug 2024

How Teachers Perceive Teacher Leadership In A Massachusetts Urban Turnaround High School: A Concurrent Mixed-Methods Case Study, Matthew Lawrence Mccarthy

Graduate Doctoral Dissertations

Turnaround schools represent a strategy for swiftly revitalizing underperforming educational institutions. This study examined how teachers perceived the role of teacher leadership within one urban turnaround high school. The study addressed the following research questions: 1. How do teachers within an urban turnaround high school conceptualize the role of teacher leadership? 2. In what ways does teacher leadership influence and contribute to the improvement of student performance in turnaround schools? This research was conducted through a concurrent mixed-methods case study that involved one urban turnaround high school. The findings offer valuable insights into teachers' perceptions of teacher leadership and its …


Engaging Survivors In Transnational Justice Governance: Global, National And Local Perspectives From Uganda's Post Lra Insurgency, Dennis Jjuuko Aug 2024

Engaging Survivors In Transnational Justice Governance: Global, National And Local Perspectives From Uganda's Post Lra Insurgency, Dennis Jjuuko

Graduate Doctoral Dissertations

The end of the Second World War established the Nuremberg trials and the Tokyo tribunal while the United Nations (UN) system established ad-hoc tribunals in the former Yugoslavia and Rwanda, and multilateralism facilitated the creation of the present-day International Criminal Court (ICC). These trials and tribunals established liberal approaches to transnational justice governance. Despite the dominance of a liberal universalist justice framework, non-liberal justice approaches have also emerged. Considered as alternative customized justice structures, including South Africa’s Truth and Reconciliation Commission (TRC) and Rwanda’s Gacaca Courts, these community emergent approaches emphasize a transformative approach to addressing legacies of civil conflict …


Exploring The Impact Of War On International Community College Students From Ukraine: A Case Study From Toronto, Oleg Legusov, Oleksandr Antonenko Aug 2024

Exploring The Impact Of War On International Community College Students From Ukraine: A Case Study From Toronto, Oleg Legusov, Oleksandr Antonenko

Journal of Comparative & International Higher Education

No abstract provided.


La1-Xsrxcoo3 Perovskite: Antimicrobial Properties And Pvdf Based Piezoelectric Nanogenerator For Energy Storage Through Self-Induced Polling, S M. Anyet Ullah Shohag Aug 2024

La1-Xsrxcoo3 Perovskite: Antimicrobial Properties And Pvdf Based Piezoelectric Nanogenerator For Energy Storage Through Self-Induced Polling, S M. Anyet Ullah Shohag

Theses and Dissertations

Piezoelectric Nanogenerators (PENGs), which can produce electrical energy from mechanical energy via ferroelectric effect, are one of the ambient sources of green energy. PENGs have gathered a huge attention due to cost-effectiveness, mechanical stability, and easy installation process. In this experiment, different weight percent of Sr2+ doped Lanthanum Cobaltite (La1- XSrXCoO3) perovskite, a ferroelectric material, was synthesizes by using a simple combination of sol-gel and molten-salt process and then characterization by X-ray diffraction, and scanning electron microscopy ensures the uniform morphology of nano cubes. Poly (vinylidene difluoride) (PVDF), N,N-dimethylformamide and acetone solution were used to make a flexible film using …


Exploratory Analysis In Rio Grande Valley Real Estate Development, Mathew C. Sosa Aug 2024

Exploratory Analysis In Rio Grande Valley Real Estate Development, Mathew C. Sosa

Theses and Dissertations

The aim of this thesis is to apply exploratory data analysis and machine learning (ML) to answer critical questions in real estate development within the Rio Grande Valley (RGV). The real estate development sector is highly dynamic and relies on multiple integrated systems and planning to bring new homes to the market. Customer Relationship Management (CRM) software and real estate listing services, such as Redfin, are utilized to manage the customer lifecycle and analyze the local market, respectively. Two of the most crucial aspects of the customer lifecycle are the first home tour and deal closing. This paper explores the …


Redefining Spaces Of Resistance Against Capitalism And Patriarchy: A Study Of Females In Society And The Family As Presented By Mrs. Warren’S Profession (1893) By Bernard Shaw And A Raisin In The Sun (1959) By Lorraine Hansberry, Jennifer L. Gonzalez Aug 2024

Redefining Spaces Of Resistance Against Capitalism And Patriarchy: A Study Of Females In Society And The Family As Presented By Mrs. Warren’S Profession (1893) By Bernard Shaw And A Raisin In The Sun (1959) By Lorraine Hansberry, Jennifer L. Gonzalez

Theses and Dissertations

These plays show how conflicts concerning race, gender, and class stem from economic distress, racial discrimination, and patriarchal oppression. Within such intersections lie distinct realities of capitalism which simultaneously upholds patriarchal ideals that can only be best understood through a Marxist-Feminist lens. This thesis pays attention to how racism and discrimination functions to isolate certain groups of people from reaching social mobility. The first chapter analyzes Mrs. Warren’s Profession to demonstrate how Mrs. Warren decision to enter into prostitution cannot simply be reduced to a question of morality, but rather a question of society’s conditions that place women into certain …


11th Circuit Denies En Banc Review Of Eknes-Tucker Panel Decision In Alabama Gender-Confirming Care Case, Generating Dissenting Opinions And “Statements”, Arthur S. Leonard Aug 2024

11th Circuit Denies En Banc Review Of Eknes-Tucker Panel Decision In Alabama Gender-Confirming Care Case, Generating Dissenting Opinions And “Statements”, Arthur S. Leonard

Other Publications

No abstract provided.


Outcomes Of Different Steroid Dosing Regimens In Critical Covid-19 Pneumonia At A Kenyan Hospital: A Retrospective Cohort Study, John Odhiambo, Jasmit Shah, Nancy Kunyiha, Felix Riunga, Charles Makasa Aug 2024

Outcomes Of Different Steroid Dosing Regimens In Critical Covid-19 Pneumonia At A Kenyan Hospital: A Retrospective Cohort Study, John Odhiambo, Jasmit Shah, Nancy Kunyiha, Felix Riunga, Charles Makasa

Internal Medicine, East Africa

Background: Among therapeutic options for severe and critical COVID- 19 infection, dexamethasone six milligrams once daily for ten days has demonstrated mortality benefit and is guideline recommended at this dose. In practice, variable doses of steroids have been used, especially in critical care settings. Our study aimed to determine the pattern of steroid dosing and outcomes in terms of critical care mortality, occurrence of dysglycaemias, and occurrence of superadded infections in patients with critical COVID-19.

Methods: A retrospective cohort study was carried out on all eligible patients admitted to the Aga Khan University Hospital, Nairobi, with critical COVID-19 between 1st …


Nutrient Intake And Nutritional Status Of Blood Cancer Patients At A Tertiary Hospital In India: A Cross-Sectional Descriptive Analysis Of Leukemia, Lymphoma And Multiple Myeloma, Enock Topisia, Loise Wamahiga Wang’Ondu Aug 2024

Nutrient Intake And Nutritional Status Of Blood Cancer Patients At A Tertiary Hospital In India: A Cross-Sectional Descriptive Analysis Of Leukemia, Lymphoma And Multiple Myeloma, Enock Topisia, Loise Wamahiga Wang’Ondu

Haematology and Oncology, East Africa

In 2018, there were an estimated 18 million cancer cases worldwide, with lymphoma, multiple myeloma, and leukemia contributing to a significant portion of these cases. Lymphoma accounted for 79,990 cases, multiple myeloma for 159,985 cases, and leukemia for 437,033 cases globally (AICR, 2018). In the United States alone, approximately 30,770 people are diagnosed with multiple myeloma each year. Multiple myeloma comprises about 1.8% of all cancers and around 10% of all “blood cancers,” which includes leukemia (Penn Medicine, 2020). India ranks third in the highest reported cases of blood cancer, following the United States and China, affecting more than 70,000 …


Creation Of Eco-Terrorism: A History Of Actions By The Earth Frist!, Earth Liberation And Animal Liberation Front From The 1980s-2000s, Zachary Smith, Zachary C. Smith Aug 2024

Creation Of Eco-Terrorism: A History Of Actions By The Earth Frist!, Earth Liberation And Animal Liberation Front From The 1980s-2000s, Zachary Smith, Zachary C. Smith

History Theses

From the nineteen eighties to the early two thousands, the United States saw a raise in awareness and activity from ecological activist groups. The United States government labeled ecological activist groups as the one domestic terrorist group that was the largest threat to the safety and well-being of the American public. Given the current environmental crisis facing the world, there should be encouragement and rise of green activism not an active dismissal. How did these activists become the number one on the United States government list? The groups that are primarily responsible for this claim are Earth First!, Earth Liberation …


Challenges Of Insulin-Like Growth Factor-1 Testing, Jieli Li Aug 2024

Challenges Of Insulin-Like Growth Factor-1 Testing, Jieli Li

Faculty, Staff and Students Publications

Insulin-like growth factor 1 (IGF-1), primarily synthesized in the liver, was initially discovered due to its capacity to replicate the metabolic effects of insulin. Subsequently, it emerged as a key regulator of the actions of growth hormone (GH), managing critical processes like cell proliferation, differentiation, and apoptosis. Notably, IGF-1 displays a longer half-life compared to GH, making it less susceptible to factors that may affect GH concentrations. Consequently, the measurement of IGF-1 proves to be more specific and sensitive when diagnosing conditions such as acromegaly or GH deficiency. The recognition of the existence of IGFBPs and their potential to interfere …