Digital Commons Network^™

Development Of Computational Imaging Pipelines To Advance Quantitative Co-Clinical Imaging And Pathology, Kaushik Dutta

McKelvey School of Engineering Graduate Student Theses & Dissertations

Deep learning driven computational methods have profoundly impacted medical imaging by advancing feature extraction, and by establishing a critical foundation for downstream image analysis and interpretation. Co-clinical trials are an emerging area of investigation in which a clinical trial is coupled with a corresponding preclinical study to inform the corresponding clinical trial to enhance translational accuracy and therapeutic development. Within this framework, quantitative imaging and pathology plays a fundamental role in both clinical and preclinical arms of co-clinical trials. Quantitative imaging enables enabling identification and validation of imaging biomarkers which are leveraged to predict therapeutic response, characterize disease phenotypes, and …

Discrete Element Method For Mining Industrial Applications: Solving The Clumping Problem Caused By Bulk Cohesive Particles In An Iron Ore Beneficiation Process, Shuang Liu

McKelvey School of Engineering Graduate Student Theses & Dissertations

The discrete element method (DEM) is a widely used numerical approach for simulating and analyzing the behavior of granular materials in various applications. This research focuses on the iron ore beneficiation process, addressing the clumping issue in cohesive iron ores from existing crushing processes through a novel double-layered disperser design. The significance of this study lies in its potential to enhance the efficiency of the existing crushing phase and improve the linkage to subsequent purification stages that target smaller-sized iron ore pellets, thereby enhancing the overall efficiency of the ore beneficiation process and achieving significant energy savings. This research adopts …

Pan-Cancer Analysis Of Rna Dysregulation, Somatic Mutations, And Matrix Stiffness Using Bioinformatics Approaches, Gongyu Tang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cancer is a complex disease driven by genetic mutations, epigenetic modifications, and alterations in the tumor microenvironment. Understanding these intricate molecular mechanisms is crucial for advancing cancer diagnosis, prognosis, and treatment. RNA sequencing (RNA-seq) has emerged as a powerful tool to study cancer by providing comprehensive insights into gene expression, alternative splicing, and mutations at the transcriptome level. This dissertation leverages RNA-seq data to explore different dimensions of cancer biology through multi-omics integration and computational approaches. The research is divided into three main projects. First, I developed OncoDB, an interactive database to analyze gene expression, methylation patterns, and viral interactions …

Discrete Element Method For Mining Industrial Applications: Solving The Clumping Problem Caused By Bulk Cohesive Particles In An Iron Ore Beneficiation Process, Shuang Liu

McKelvey School of Engineering Graduate Student Theses & Dissertations

The discrete element method (DEM) is a widely used numerical approach for simulating and analyzing the behavior of granular materials in various applications. This research focuses on the iron ore beneficiation process, addressing the clumping issue in cohesive iron ores from existing crushing processes through a novel double-layered disperser design. The significance of this study lies in its potential to enhance the efficiency of the existing crushing phase and improve the linkage to subsequent purification stages that target smaller-sized iron ore pellets, thereby enhancing the overall efficiency of the ore beneficiation process and achieving significant energy savings. This research adopts …

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites And Insufficiently Reclaimed Areas – Racetrack Borrow Material Usage (Dated December 19, 2024), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

November 2024 Berkeley Pit Migratory Waterfowl Protection Monthly Report, Mark Thompson, Loren Burmeister

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Molten Flux Synthesis Of Plutonium (Iv) Silicates K2Pusi2O7 And Rb2Pusi6O15, Travis K. Deason, Gregory Morrison, Amir Mofrad, Jake Amoroso, David Diprete, Theodore M. Besmann, Shanna L. Estes, Hans Conrad Zur Loye

Faculty Publications

Few plutonium containing silicates have been reported in the literature and only one other tetravalent plutonium silicate structure has been reported using the flux growth method. With the goal of understanding actinide incorporation into silicates, we describe herein two new plutonium (IV) silicates, Rb2PuSi6O15 and K2PuSi2O7, synthesized using a mixed alkali chloride/alkali fluoride flux growth. Both structures crystallize in the C2/c space group with lattice parameters a=24.2980(10) Å, b=7.1466(3) Å, c=17.2025(8) Å and 96.6560(10)° for Rb2PuSi6O15, and a=9.9478(2) Å, b=5.59820 (10) Å, c=13.1848(2) Å, and 105.7400(10)° for K2PuSi2O7. Comparisons to the synthesis of other reported alkali actinide silicates (Ce, U, …

Integrating Traditional And Western Healing Practices For American Indian Patients, Victoria Blacksmith

Walden Dissertations and Doctoral Studies

The American Indian/Alaska Native (AI/AN) community experiences disproportionally high rates of mental health disorders. Although research had examined the benefits of using traditional AI/AN health practices, little was known about how integrating traditional and Western treatment methods works. Using historical trauma theory and oppression theory, this qualitative study explored how AI/AN clinicians integrate traditional health practices into Western treatment methods when treating mental health disorders in AI/AN patients. Data were collected through semistructured interviews with five clinicians. Data analysis via deductive coding revealed two main themes: lived experiences of AI/AN clinicians and integration strategies. Cultural knowledge was the most prominent …

Electric Utility Industry Safety Plan Filing And Accident Reporting Impact On The Number Of Accidents, Rishi Singh

Walden Dissertations and Doctoral Studies

Safety is of paramount importance in the electric utility industry. Construction is the basis of electric work and is one of the most dangerous industries, with a high rate of accidents and fatalities. The purpose of this quantitative correlational study was to examine the relationship between the organizational leaders’ decision to file safety plans and accident reporting to the Occupational Safety and Health Administration or utility commissions on the number of accidents in the electric utility industry. The decision-making theory provided the study’s foundation. The study used secondary data from 2019 to 2023 for electric utility companies from California. Published …

The Search For Unenumerated Fundamental Rights, Alina Sluzhyvenkova

Student Theses and Dissertations

There are certain rights that are explicitly enumerated in the Constitution, e.g., right to bear arms, right to free speech, right to a speedy and public trial. There are also rights that aren’t specifically written out but are nevertheless enjoyed by people nationwide. Rights that aren’t explicitly mentioned in the Constitution, but which are fundamental to are called the unenumerated rights. Unenumerated rights are just as important and can be derived from natural law, enumerated rights, the Ninth Amendment, precedents, judicial opinions, and substantive due process.

Substantive due process is a principle guaranteed by the Fifth and Fourteenth Amendments, which …

On Relationship Between Experiment And Theory In Basic Scientific Research, Changpu Sun

Bulletin of Chinese Academy of Sciences (Chinese Version)

Understanding how experiments in basic scientific research “confirm” theories is crucial for upholding the spirit of science and fostering technological innovation. Mr. Zhou Guangzhao conducted an in-depth discussion on this topic in his early work. This study further analyzes the issue from the perspective of the philosophy of science. We derive falsificationism from a Bayesian perspective, providing a philosophical understanding of the proper handling of the relationship between scientific theory and experiment. By examining the relationship between theory and experiment in physics, this study proposes a philosophy of science concept of progressive falsifiability, emphasizing that through Bayesian methods, experiments can …

Action Logic And Agenda Game Of Global Methane Emission Control And China’S Countermeasures, Bo Zhang, Jinling Guo, Bing Zhong, Junlian Gao, Guosheng Zhang, He Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Originated from the global response to climate change, methane emission control has evolved into a focus of international climate negotiations in recent years. At present, the agenda for controlling methane emission in global climate governance is basically taking shape, but in the process of shifting from scientific consensus to political consensus, the content of the topic and the focus of the game continue to evolve. To carry out global action, it is necessary to address issues such as the allocation of responsibilities, international rules, climate investment and financing, and risk prevention, as well as the basic capacity guarantees behind them. …

Architecture And Key Technologies Of New Research Informatization Infrastructure Platform Under The Fifth Research Paradigm, Fangyu Liao, Yang Wang, Rongqiang Cao, Bo Zhang, Zhenyu Li, Huajin Wang, Xin Chen, Dong Li, Yangang Wang, Xin Wei

Bulletin of Chinese Academy of Sciences (Chinese Version)

The basic platform of research informatization is an indispensable pedestal for modern scientific research and an important manifestation of national scientific and technological innovation capability. As the research paradigm continues to evolve, the architecture and technologies of research informatization infrastructure platform are bound to evolve as well. The new research paradigm brings unique demands and challenges to the algorithmic computility, network transmission capacity, and data storage and management. Consequently, it is an urgent requirement for research informatization infrastructure platform to make technological breakthroughs in the areas of intelligent computility, large-scale data storage and high throughput read/write, cross-network software and hardware …

Overall Promotion Of Integrated Management And Utilization Of Saline-Alkali Land In Northwest China: Conditions, Challenges, And Recommendations, Qi Feng, Xinwei Yin, Meng Zhu, Jutao Zhang, Wei Liu, Haiyang Xi, Tengfei Yu, Linshan Yang, Wen Liu, Zhixiang Lu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Cultivated land is the lifeblood of grain production and the foundation for food security. Saline-alkali land in Northwest China is an important cultivated land reserve resource and a potential granary for guaranteeing national food security, so the high-quality promotion of comprehensive management and utilization of saline-alkali land in Northwest China is a strategic measure to achieve the goal of “storing grain in land and technology”. Based on a profound understanding of the great significance for promoting the integrated management and utilization of saline-alkali land in Northwest China, this study systematically summarizes the quantity, distribution pattern, and utilization potential of saline-alkali …

China’S Rare Earths Trade Flow Analysis: Trade Patterns And Strategic Insights, Linbin Tang, Peng Wang, Wei Chen, Yawen Han, Yuning Jin, Zilong Peng, Weiqiang Chen

Bulletin of Chinese Academy of Sciences (Chinese Version)

Rare earth elements are strategic critical metals that support low-carbon energy, aerospace, and defense technologies. Currently, China’s rare earth industry lacks competitiveness and faces the risk of “multidimensional pressures” in global competition. Therefore, it is crucial to systematically analyze the supply-demand and trade patterns of rare earths, accurately identify the bottlenecks and pain points in China’s entire rare earth industry chain, and provide strategies to transform China’s rare earth resource advantage into a strategic competitive edge. Based on customs trade data, this study traces the trade flows of various forms of rare earth products across the full industry chain in …

How Should China Respond To “Pan-Data Sovereignty” Competition Among China, U.S., And Eu—An Analysis Based On The Digital Stack Model?, Yan Liu, Congjing Ran

Bulletin of Chinese Academy of Sciences (Chinese Version)

Data sovereignty has become deeply intertwined with various economic and social development factors such as technology, trade, economy, culture, society, and politics, leading to a “Pan-Data Sovereignty” competition pattern in the digital space. Through the digital stack model, which examines digital technologies in a layered framework, we can more clearly assess the competitive capacities in“Pan-Data Sovereignty” of China, United States, and European Union. The analysis identifies a three-tiered global “Pan-Data Sovereignty” competition structure among China, U.S., and EU, with each entity holding distinct advantages across various layers of the digital stack. Intense future competition is anticipated in fields such as …

Research And Reflection On Transformation Of Resource-Based Cities In China—A Case Study Of Datong City, Shanxi Province, Zhijian Xiong, Hong Zhao, Xiuli Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Currently, there are 262 resource-based cities in China, of which mature and declining cities account for 79.39%. These cities have made significant contributions to the country’s economic and social development, but now they are facing severe challenges and difficulties, and their transformation problems urgently need to be solved. This work studies the mechanism of resource-based transformation and proposes strategies for the transformation of resource-based cities: (1) Transformation should be comprehensive, balanced, and sustainable; (2) Transformation should fully leverage the leading role of the market while also taking into account the fundamental role of the government; (3) Transformation should fully leverage …

A Comprehensive Usability And Economic Analysis Of Heat-Related Wearable Technologies: Applications To Occupational Health, Ryan T. Cannady

Theses & Dissertations

The purpose of this research was to analyze the usability and economic considerations of real-time wearable technologies that are implemented in occupational settings to assess risk of heat stress and heat strain. The study population included current agriculture workers and Department of Energy (DOE), Environmental Management (EM) contractors. We employed a mixed-methods approach to comprehensively analyze the usability and economic considerations of heat-related technologies. Specifically, our approach assessed three distinct aspects the applications of these technologies in occupational settings to comprehensively address our research objective: (1) worker perceptions of heat-related wearable technologies, (2) field-based assessment of these heat-related wearable technologies, …

Enhancing Concrete Sustainability With Self-Healing Technologies, Al Shimaa Abdullatif

Theses and Dissertations

Thanks to its strength, durability and affordability, Portland cement concrete is the most commonly used building material worldwide. However, concrete cracking is inevitable due to numerous factors including shrinkage, exposure to external chemicals, internals reactions, excessive loads, to name but a few. Self-healing is a promising technique that can enable concrete to autogenously heal cracks and alleviate much of the damage. Such healing can without a doubt extend the service life with less need for external repair works therefore it contributes to sustainability. Over the years, several means of self-healing agents have been explored including bio-based procedures and the incorporation …

Womb, Gravity, And Space: Shifting Towards The Cerebellum-Basal Ganglia Paradigm In Dystonia, Diego Iacono

Department of Neurology Faculty Papers

No abstract provided.

Protocol For Monitoring Clonal Hematopoiesis In Transgenic Mouse Models Using Multispectral Imaging, Priyanka Khanna, Lauren B Ostermann, Shayaun Khazaei, Ran Zhao, Michael Andreeff

Faculty, Staff and Student Publications

Clonal hematopoiesis involves the clonal expansion of hematopoietic cells, potentially progressing into hematological malignancies. Here, we present a protocol for the development and characterization of two mouse models designed to simulate clonal hematopoiesis and acute myeloid leukemia. We describe steps for model generation, monitoring clonal expansion, harvesting, fixation, and staining of bone marrow and spleen tissues. We specifically focus on the visualization and analysis of p53 mutant clonal expansions, providing a comprehensive protocol for studying these phenomena in mouse models. For complete details on the use and execution of this protocol, please refer to Pourebrahim et al.

Impact Of Global Environmental Changes On The Range Contraction Of Eurasian Moose Since The Late Pleistocene, Magdalena Niedziałkowska, Marcin Górny, Joanna Gornia, Danijela Popović, Mateusz Baca, Urszula Ratajczak-Skrzatek, Oleksandr Kovalchuk, Maciej Sykut, Małgorzata Suska-Malawska, Paweł Mackiewicz, Emilia Hofman-Kamińska, Rafał Kowalczyk, Maxim Czarniauski, Kamilla Pawłowska, Daniel Makowiecki, Larisa Tataurova, Alexey Bondarev, Andrey Shpansky, Albert V. Protopopov, Aleksandr Dmitrievich Sorokin, Urmas Saarma, Pavel Kosintsev, Ulrich Schmölcke, Jarosław Wilczyński, Grzegorz Lipecki, Adam Nadachowski, Gennady G. Boeskorov, Gennady F. Baryshnikov, Roberto Zorzin, Nadezhda Vorobiova

School of Geography, Earth and Environmental Sciences

Climatic oscillations are considered primary factors influencing the distribution of various life forms on Earth. Large species adapted to cold climates are particularly vulnerable to extinction due to climate changes. In our study, we investigated whether temperature increase since the Late Pleistocene and the contraction of environmental niche during the Holocene were the main factors contributing to the decreasing range of moose (Alces alces) in Europe. We also examined whether there were significant differences in environmental conditions between areas inhabited by moose in Europe and Asia, that could support the division of moose into western and eastern forms, as suggested …

Integrating Traditional And Western Healing Practices For American Indian Patients, Victoria Blacksmith

Walden Dissertations and Doctoral Studies

The American Indian/Alaska Native (AI/AN) community experiences disproportionally high rates of mental health disorders. Although research had examined the benefits of using traditional AI/AN health practices, little was known about how integrating traditional and Western treatment methods works. Using historical trauma theory and oppression theory, this qualitative study explored how AI/AN clinicians integrate traditional health practices into Western treatment methods when treating mental health disorders in AI/AN patients. Data were collected through semistructured interviews with five clinicians. Data analysis via deductive coding revealed two main themes: lived experiences of AI/AN clinicians and integration strategies. Cultural knowledge was the most prominent …

Electric Utility Industry Safety Plan Filing And Accident Reporting Impact On The Number Of Accidents, Rishi Singh

Walden Dissertations and Doctoral Studies

Safety is of paramount importance in the electric utility industry. Construction is the basis of electric work and is one of the most dangerous industries, with a high rate of accidents and fatalities. The purpose of this quantitative correlational study was to examine the relationship between the organizational leaders’ decision to file safety plans and accident reporting to the Occupational Safety and Health Administration or utility commissions on the number of accidents in the electric utility industry. The decision-making theory provided the study’s foundation. The study used secondary data from 2019 to 2023 for electric utility companies from California. Published …

Neuvac: Nonlinear Extreme Ultraviolet Irradiance Model For Aeronomic Calculations, Daniel A. Brandt, Aaron J. Ridley

Michigan Tech Publications

The need for reliable estimates of solar extreme ultraviolet (EUV) for operational space weather nowcasting and forecasting has motivated the development of new model of solar irradiance variability in 59 wavelength bins between 1 and 1,750 Å. The model employs a nonlinear parameterization of rebinned daily FISM2 irradiances and is termed NEUVAC: Nonlinear Extreme Ultraviolet Irradiance Model for Aeronomic Calculations. The model is parameterized in terms of F10.7 and 54-day averaged F10.7 in a backwards-looking window. The model takes advantage of the high accuracy and resolution of FISM2, and the consistent availability of F10.7 data in order to provide the …

Benefits Marketplace, Ana Luisa Wu, Jenny Ramirez, Jose Ricardo Tafur Jr, Ricardo Collada, Maikel Zuniga, Manuel Ferreiro Caballero, Salvador Ricardo, Liset Iturriaga Chavez, Francisco Alberdi, Alexander Dale, Orlando Quesada, Ernesto Garcia Vazquez, Daniel Astudillo, Laura Figueroa, Sebastian Hernandez, Cristina Villarroel, Yuset Rosello Moya, Rachel Quijano Vizoso

Defensive Publications Series

A method of provisioning a benefits marketplace platform is disclosed. According to the method, a payment network server computer presents payment network benefits to a consumer and receives feedback from the consumer based on the payment network benefits presented to the consumer. A profiling module profiles the payment network benefits based on the feedback received from the consumer and provides a benefits profile to the payment network server computer. The payment network server provides a recommendation of benefits to the consumer based on the benefits profile. A benefits module receives benefits selected by the consumer from a checkout function, applies …

Primates In Paradise: Critical Possibilities Of The Milieu Movie, Joel David

Kritika Kultura

The use of multiple lead characters in cinema is a fairly recent development, although the strategy (and its resultant variety of structures) had been present for some time in theater and literature. The typical Classical Hollywood action-driven narrative operated most efficiently through a singular hero, allowing the audience to undergo the film experience via the process of singular identification. With the breakdown in identificatory requisites popularized by various New Wave and Third Cinema movements, and the consequent assimilation of this trend starting with the New American Cinema, mainstream Hollywood was ready to embark upon a series of multi-character movies, with …

"Transmedial Aesthetics Is Ordinary": Some Remarks On Victor Eriche's The Spirit Of The Beehive, Jan Baetens

Kritika Kultura

Focusing on Victor Erice’s 1973 movie, The Spirit of the Beehive, this article proposes to rethink the problem of adaptation with the help of the concept of “experience” (freely borrowed from Dewey). The emphasis on the reception of a given work (in this case James Whale’s 1931 Frankenstein, a very particular screening of which is part of the movie’s diegesis) will foreground the importance of the process of intermedialization or “intermediality in action,” an all-encompassing culturally embedded experience, which is more existential than aesthetic.

Sisa's Vengeance: Rizal And The Mother Of All Insurgencies, E. San Juan Jr.

Kritika Kultura

A new appraisal of Rizal is needed today in the light of 9/11, the collapse of finance capital, state terrorism, and neoliberal decadence and barbarism. Rizal’s revolutionary critique can be discovered by shifting the center of inquiry to the Dapitan years and after, the Liga’s resonance, and the Sisa-Maria Clara-Salome nexus. By exposing the limits of Simoun’s romantic idealism, Padre Florentino’s eschatological impulse, and the carnivalesque colonial world bereft of god/nomos, Rizal anticipates the post-capitalist predicament. Women’s vengeance against patriarchal nihilism lies submerged in Rizal’s communicative action to the Malolos collective, mobilizing emergent and residual historical forces in a dialectical …

Philippine Studies And The End Of The American Century, Cynthia Tolentino

Kritika Kultura

The current struggles over US military bases and territorial sovereignty in the Pacific, wars in Iraq and Afghanistan, and the phenomenon of globalization, alongside what is being called the “end of the American Century,” have pushed interdisciplinary scholars to develop new frameworks for engaging US Empire. The paper attempts to draw out the various figurations of “Philippine Studies” and “US empire” in the papers, which may include analyses of comparative colonialisms, class and participation in social justice movements, as well as the intersections between globalization and imperial conquest. By considering the papers’ insights on disciplinary formation and knowledge practices, the …