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Protocol For Monitoring Clonal Hematopoiesis In Transgenic Mouse Models Using Multispectral Imaging, Priyanka Khanna, Lauren B Ostermann, Shayaun Khazaei, Ran Zhao, Michael Andreeff Dec 2024

Protocol For Monitoring Clonal Hematopoiesis In Transgenic Mouse Models Using Multispectral Imaging, Priyanka Khanna, Lauren B Ostermann, Shayaun Khazaei, Ran Zhao, Michael Andreeff

Faculty, Staff and Student Publications

Clonal hematopoiesis involves the clonal expansion of hematopoietic cells, potentially progressing into hematological malignancies. Here, we present a protocol for the development and characterization of two mouse models designed to simulate clonal hematopoiesis and acute myeloid leukemia. We describe steps for model generation, monitoring clonal expansion, harvesting, fixation, and staining of bone marrow and spleen tissues. We specifically focus on the visualization and analysis of p53 mutant clonal expansions, providing a comprehensive protocol for studying these phenomena in mouse models. For complete details on the use and execution of this protocol, please refer to Pourebrahim et al.

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Beyond Bindis, Bhajis, Bangles And Bhangra: Promoting Multiculturalism In Primary Schools In Predominantly White British Places, Suparna Bagchi Dec 2024

Beyond Bindis, Bhajis, Bangles And Bhangra: Promoting Multiculturalism In Primary Schools In Predominantly White British Places, Suparna Bagchi

School of Law, Humanities and Social Sciences

Twenty-first-century education as a powerful means of knowledge will possibly be shaped by the emphasis it places on having classrooms that are race-conscious and multicultural. The present article is based on a doctoral study that explores an under-researched area: experiences and understanding of multiculturalism in mainstream primary schools situated in the predominantly White places of Southwest England. The study was underpinned by a sociocultural theoretical framework; data were collected through semi-structured interviews with the adult participants, students’ classroom activities, and documentary analysis of school displays. The article focuses on the data generated from the students’ classroom activities. Findings show differences …

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The Occurrence And Biogeochemical Cycling Of Quaternary, Ternary And Volatile Amines In Marine Systems, Mark Fitzsimons, Ruth Airs, Yin Chen Dec 2024

The Occurrence And Biogeochemical Cycling Of Quaternary, Ternary And Volatile Amines In Marine Systems, Mark Fitzsimons, Ruth Airs, Yin Chen

School of Geography, Earth and Environmental Sciences

This review provides a critical assessment of knowledge regarding the occurrence and behaviour of volatile, low molecular weight amines, particularly methylamines and quaternary amines, in marine aquatic systems. It provides an up-to-date evaluation of their presence within marine ecosystems, the processes likely to control their flux across the sea-air interface, and analytical techniques associated with their measurement. Interest in the occurrence and cycling of these groups of compounds in seawater has increased within the last 10–15 years, due to their potential role in climate regulation. As such, the need for wider measurements and mechanistic studies to elucidate their role within …

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Impact Of Global Environmental Changes On The Range Contraction Of Eurasian Moose Since The Late Pleistocene, Magdalena Niedziałkowska, Marcin Górny, Joanna Gornia, Danijela Popović, Mateusz Baca, Urszula Ratajczak-Skrzatek, Oleksandr Kovalchuk, Maciej Sykut, Małgorzata Suska-Malawska, Paweł Mackiewicz, Emilia Hofman-Kamińska, Rafał Kowalczyk, Maxim Czarniauski, Kamilla Pawłowska, Daniel Makowiecki, Larisa Tataurova, Alexey Bondarev, Andrey Shpansky, Albert V. Protopopov, Aleksandr Dmitrievich Sorokin, Urmas Saarma, Pavel Kosintsev, Ulrich Schmölcke, Jarosław Wilczyński, Grzegorz Lipecki, Adam Nadachowski, Gennady G. Boeskorov, Gennady F. Baryshnikov, Roberto Zorzin, Nadezhda Vorobiova Dec 2024

Impact Of Global Environmental Changes On The Range Contraction Of Eurasian Moose Since The Late Pleistocene, Magdalena Niedziałkowska, Marcin Górny, Joanna Gornia, Danijela Popović, Mateusz Baca, Urszula Ratajczak-Skrzatek, Oleksandr Kovalchuk, Maciej Sykut, Małgorzata Suska-Malawska, Paweł Mackiewicz, Emilia Hofman-Kamińska, Rafał Kowalczyk, Maxim Czarniauski, Kamilla Pawłowska, Daniel Makowiecki, Larisa Tataurova, Alexey Bondarev, Andrey Shpansky, Albert V. Protopopov, Aleksandr Dmitrievich Sorokin, Urmas Saarma, Pavel Kosintsev, Ulrich Schmölcke, Jarosław Wilczyński, Grzegorz Lipecki, Adam Nadachowski, Gennady G. Boeskorov, Gennady F. Baryshnikov, Roberto Zorzin, Nadezhda Vorobiova

School of Geography, Earth and Environmental Sciences

Climatic oscillations are considered primary factors influencing the distribution of various life forms on Earth. Large species adapted to cold climates are particularly vulnerable to extinction due to climate changes. In our study, we investigated whether temperature increase since the Late Pleistocene and the contraction of environmental niche during the Holocene were the main factors contributing to the decreasing range of moose (Alces alces) in Europe. We also examined whether there were significant differences in environmental conditions between areas inhabited by moose in Europe and Asia, that could support the division of moose into western and eastern forms, as suggested …

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Integrating Traditional And Western Healing Practices For American Indian Patients, Victoria Blacksmith Dec 2024

Integrating Traditional And Western Healing Practices For American Indian Patients, Victoria Blacksmith

Walden Dissertations and Doctoral Studies

The American Indian/Alaska Native (AI/AN) community experiences disproportionally high rates of mental health disorders. Although research had examined the benefits of using traditional AI/AN health practices, little was known about how integrating traditional and Western treatment methods works. Using historical trauma theory and oppression theory, this qualitative study explored how AI/AN clinicians integrate traditional health practices into Western treatment methods when treating mental health disorders in AI/AN patients. Data were collected through semistructured interviews with five clinicians. Data analysis via deductive coding revealed two main themes: lived experiences of AI/AN clinicians and integration strategies. Cultural knowledge was the most prominent …

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Electric Utility Industry Safety Plan Filing And Accident Reporting Impact On The Number Of Accidents, Rishi Singh Dec 2024

Electric Utility Industry Safety Plan Filing And Accident Reporting Impact On The Number Of Accidents, Rishi Singh

Walden Dissertations and Doctoral Studies

Safety is of paramount importance in the electric utility industry. Construction is the basis of electric work and is one of the most dangerous industries, with a high rate of accidents and fatalities. The purpose of this quantitative correlational study was to examine the relationship between the organizational leaders’ decision to file safety plans and accident reporting to the Occupational Safety and Health Administration or utility commissions on the number of accidents in the electric utility industry. The decision-making theory provided the study’s foundation. The study used secondary data from 2019 to 2023 for electric utility companies from California. Published …

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Neuvac: Nonlinear Extreme Ultraviolet Irradiance Model For Aeronomic Calculations, Daniel A. Brandt, Aaron J. Ridley Dec 2024

Neuvac: Nonlinear Extreme Ultraviolet Irradiance Model For Aeronomic Calculations, Daniel A. Brandt, Aaron J. Ridley

Michigan Tech Publications

The need for reliable estimates of solar extreme ultraviolet (EUV) for operational space weather nowcasting and forecasting has motivated the development of new model of solar irradiance variability in 59 wavelength bins between 1 and 1,750 Å. The model employs a nonlinear parameterization of rebinned daily FISM2 irradiances and is termed NEUVAC: Nonlinear Extreme Ultraviolet Irradiance Model for Aeronomic Calculations. The model is parameterized in terms of F10.7 and 54-day averaged F10.7 in a backwards-looking window. The model takes advantage of the high accuracy and resolution of FISM2, and the consistent availability of F10.7 data in order to provide the …

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Benefits Marketplace, Ana Luisa Wu, Jenny Ramirez, Jose Ricardo Tafur Jr, Ricardo Collada, Maikel Zuniga, Manuel Ferreiro Caballero, Salvador Ricardo, Liset Iturriaga Chavez, Francisco Alberdi, Alexander Dale, Orlando Quesada, Ernesto Garcia Vazquez, Daniel Astudillo, Laura Figueroa, Sebastian Hernandez, Cristina Villarroel, Yuset Rosello Moya, Rachel Quijano Vizoso Dec 2024

Benefits Marketplace, Ana Luisa Wu, Jenny Ramirez, Jose Ricardo Tafur Jr, Ricardo Collada, Maikel Zuniga, Manuel Ferreiro Caballero, Salvador Ricardo, Liset Iturriaga Chavez, Francisco Alberdi, Alexander Dale, Orlando Quesada, Ernesto Garcia Vazquez, Daniel Astudillo, Laura Figueroa, Sebastian Hernandez, Cristina Villarroel, Yuset Rosello Moya, Rachel Quijano Vizoso

Defensive Publications Series

A method of provisioning a benefits marketplace platform is disclosed. According to the method, a payment network server computer presents payment network benefits to a consumer and receives feedback from the consumer based on the payment network benefits presented to the consumer. A profiling module profiles the payment network benefits based on the feedback received from the consumer and provides a benefits profile to the payment network server computer. The payment network server provides a recommendation of benefits to the consumer based on the benefits profile. A benefits module receives benefits selected by the consumer from a checkout function, applies …

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Primates In Paradise: Critical Possibilities Of The Milieu Movie, Joel David Dec 2024

Primates In Paradise: Critical Possibilities Of The Milieu Movie, Joel David

Kritika Kultura

The use of multiple lead characters in cinema is a fairly recent development, although the strategy (and its resultant variety of structures) had been present for some time in theater and literature. The typical Classical Hollywood action-driven narrative operated most efficiently through a singular hero, allowing the audience to undergo the film experience via the process of singular identification. With the breakdown in identificatory requisites popularized by various New Wave and Third Cinema movements, and the consequent assimilation of this trend starting with the New American Cinema, mainstream Hollywood was ready to embark upon a series of multi-character movies, with …

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"Transmedial Aesthetics Is Ordinary": Some Remarks On Victor Eriche's The Spirit Of The Beehive, Jan Baetens Dec 2024

"Transmedial Aesthetics Is Ordinary": Some Remarks On Victor Eriche's The Spirit Of The Beehive, Jan Baetens

Kritika Kultura

Focusing on Victor Erice’s 1973 movie, The Spirit of the Beehive, this article proposes to rethink the problem of adaptation with the help of the concept of “experience” (freely borrowed from Dewey). The emphasis on the reception of a given work (in this case James Whale’s 1931 Frankenstein, a very particular screening of which is part of the movie’s diegesis) will foreground the importance of the process of intermedialization or “intermediality in action,” an all-encompassing culturally embedded experience, which is more existential than aesthetic.

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Sisa's Vengeance: Rizal And The Mother Of All Insurgencies, E. San Juan Jr. Dec 2024

Sisa's Vengeance: Rizal And The Mother Of All Insurgencies, E. San Juan Jr.

Kritika Kultura

A new appraisal of Rizal is needed today in the light of 9/11, the collapse of finance capital, state terrorism, and neoliberal decadence and barbarism. Rizal’s revolutionary critique can be discovered by shifting the center of inquiry to the Dapitan years and after, the Liga’s resonance, and the Sisa-Maria Clara-Salome nexus. By exposing the limits of Simoun’s romantic idealism, Padre Florentino’s eschatological impulse, and the carnivalesque colonial world bereft of god/nomos, Rizal anticipates the post-capitalist predicament. Women’s vengeance against patriarchal nihilism lies submerged in Rizal’s communicative action to the Malolos collective, mobilizing emergent and residual historical forces in a dialectical …

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Philippine Studies And The End Of The American Century, Cynthia Tolentino Dec 2024

Philippine Studies And The End Of The American Century, Cynthia Tolentino

Kritika Kultura

The current struggles over US military bases and territorial sovereignty in the Pacific, wars in Iraq and Afghanistan, and the phenomenon of globalization, alongside what is being called the “end of the American Century,” have pushed interdisciplinary scholars to develop new frameworks for engaging US Empire. The paper attempts to draw out the various figurations of “Philippine Studies” and “US empire” in the papers, which may include analyses of comparative colonialisms, class and participation in social justice movements, as well as the intersections between globalization and imperial conquest. By considering the papers’ insights on disciplinary formation and knowledge practices, the …

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Childhood And Family In Contemporary Children's Fiction: Resilience, Agency, And Emergence Of New Gender Norms, Rosario Torres-Yu Dec 2024

Childhood And Family In Contemporary Children's Fiction: Resilience, Agency, And Emergence Of New Gender Norms, Rosario Torres-Yu

Kritika Kultura

New awareness of re-thinking childhood in the emergent field of childhood studies inspires production of new discourse on social construction of childhood in literature. This paper looks at contemporary children’s literature in the Philippines from this perspective and within the context of the globalization and transnationalization of care giving. Its interrogation of selected children’s books and literature for young adult reveals that the traditional concept of childhood is now being challenged and resisted. Cognizant of the need to sustain this direction of literary production, this paper posits that children’s literature in the country should mainstream this new thinking so that …

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Gmr-4234 Evaluating Instance Segmentation Models On Histopathology Datasets, Sai Chandana Koganti Dec 2024

Gmr-4234 Evaluating Instance Segmentation Models On Histopathology Datasets, Sai Chandana Koganti

C-Day Computing Showcase

Instance segmentation is transforming digital pathology by enhancing the speed and accuracy of tissue sample analysis through advanced image processing techniques. Whole Slide Imaging (WSI) converts traditional microscope slides into high-resolution digital formats, enabling detailed examinations. This paper presents a brief experimental survey of instance segmentation models on two prominent histopathology datasets: PanNuke and NuCLS. Unlike previous surveys that merely describe deep learning models for general pathology images, we conduct experiments using state-of-the-art models including Mask R-CNN, Detectron2, YOLOv8, YOLOv9, and HoverNet on both datasets. Our study evaluates these models for both binary and multiclass instance segmentation tasks. The NuCLS …

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Gpr-187 Deep Learning Models For Protein-Protein Binding Affinity Prediction, Lingtao Chen Dec 2024

Gpr-187 Deep Learning Models For Protein-Protein Binding Affinity Prediction, Lingtao Chen

C-Day Computing Showcase

Binding affinity (BA) prediction is important for drug discovery and protein engineering. It seeks to understand the interaction strength between proteins and their ligands (or proteins). This information assists in the design of proteins with enhanced or novel functions, as well as understanding the molecular mechanisms of drug action. This paper presents the development and comparative analysis of two deep learning models, a convolutional neural network (CNN) and a transformer model. Many variants of models in this research were developed using TensorFlow. One model that utilizes ProteinBERT was developed using PyTorch. The CNN model captures local sequence features effectively, while …

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Gmr-196 Integrated Sentiment And Behavioral Analysis Of Online Product Reviews, Kiran Yepuri, Naveen Mahankali Dec 2024

Gmr-196 Integrated Sentiment And Behavioral Analysis Of Online Product Reviews, Kiran Yepuri, Naveen Mahankali

C-Day Computing Showcase

The "Integrated Sentiment and Behavioral Analysis of Online Product Reviews" project helps businesses gain actionable insights from Product reviews by combining sentiment and behavioral analysis using NLP models like VADER and BERT. This dual approach categorizes reviews as positive, neutral, or negative and identifies themes such as preferences and complaints through Named Entity Recognition and topic modeling. By capturing both the emotional tone and specific product feedback, this method highlights consumer likes and pain points, assisting in targeted improvements for product design and customer service. The project addresses challenges in analyzing complex expressions like sarcasm, providing a robust framework for …

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Gpr-185 A Multimodal Approach To Quiz Generation: Leveraging Rag Models For Educational Assessments, Mourya Teja Kunuku Dec 2024

Gpr-185 A Multimodal Approach To Quiz Generation: Leveraging Rag Models For Educational Assessments, Mourya Teja Kunuku

C-Day Computing Showcase

Crafting quiz questions that effectively assess students’ understanding of lectures and course materials, such as textbooks, poses significant challenges. Recent AI-based quiz generation efforts have predominantly concentrated on static resources, like textbooks and slides, often overlooking the dynamic and interactive elements of live lectures—contextual cues, discussions, and interactions—that contribute to the learning experience. In this work, we propose a Retrieval-Augmented Generation (RAG) model that processes multimodal inputs by combining text, audio, and video to produce quizzes that capture a fuller context. Our method incorporates Whisper for audio transcription and utilizes a Large Vision-Language Model (LVLM) to extract essential visual data …

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Uc-184 Onaccount A Web-Based Accounting Software, Manuel A Jackson, Russell E Steele, Grzegorz Loj, Zachary B Powell Dec 2024

Uc-184 Onaccount A Web-Based Accounting Software, Manuel A Jackson, Russell E Steele, Grzegorz Loj, Zachary B Powell

C-Day Computing Showcase

This project streamline and improve the efficiency of the whole accounting process, by using current best practices for user interaction engineering and current design practices. Our software should be able to provide secure, user-friendly, and accessible financial management solutions anywhere and everywhere through various devices including desktop and mobile. Allowing users to manage their accounts whenever it seems necessary while still maintaining a high level of security. The project is inspired by the various complexity and problems regarding the accounting process in the real world such as financial reporting, miscalculations, and data security; by streamlining this process and making it …

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Clinical Applications Of Phenomenology: Analysis Of Lived Experience Of Eye Disease, Kimberly Tucker Dec 2024

Clinical Applications Of Phenomenology: Analysis Of Lived Experience Of Eye Disease, Kimberly Tucker

Graduate Student Research Symposium

This paper presents a phenomenological study that explores the embodied experience of vision loss within the context of eye disease, while also providing a detailed discussion of the methodological approaches utilized in the research. Phenomenology is integrated to address clinical epistemic concerns, particularly the limitations of conventional vision tests in fully capturing perception and the lived experiences of vision loss. This interdisciplinary approach builds on the clinical understanding of eye disease by incorporating the broader dimensions of the lifeworld that intersect with visual impairment in degenerative eye diseases. While standard clinical approaches focus primarily on measurable aspects of visual function, …

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Accessing U.S. Census Bureau Data And Insights From The Release Of The American Community Survey, Josie Gatti Schafer Dec 2024

Accessing U.S. Census Bureau Data And Insights From The Release Of The American Community Survey, Josie Gatti Schafer

CPAR Presents: A Data and Research Series for Community Impact

In this timely session you will learn how to access the most recent data resources available from the U.S. Census Bureau and learn about the most recent trends in Nebraska.

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Neuroqueering As Culturally Sustaining Practice, Nathan Hughes, Meaghan Krazinski Dec 2024

Neuroqueering As Culturally Sustaining Practice, Nathan Hughes, Meaghan Krazinski

Ought: The Journal of Autistic Culture

This article explores how neuroqueering can be a complementary component to culturally-sustaining practices (Paris & Alim, 2014), and explores how culturally sustaining frameworks can affirm neurodiversity. Issues such as criminalization of Autistic people of color, and implications of diagnosis disparities and barriers to receiving services are well known (Kearl, 2021). As Gordon (2021) notes, Centering Autistic culture (#BlackAutisticJoy) and ways of being is an important part of affirming Autistic students' identities. Culturally sustaining practices (Paris & Alim, 2014) that seek to provide supportive classroom spaces that affirm students’ culture and identity must also include attention to …

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Not The Absentminded Professor: Autistic Experience And Representation In Academia, Martin Brick Dec 2024

Not The Absentminded Professor: Autistic Experience And Representation In Academia, Martin Brick

Ought: The Journal of Autistic Culture

While there are many facets of a career in academia that may be amendable to autistics, the discipline also presents a number of challenges. These hardships can be exacerbated by misunderstandings or even discrimination from colleagues and administrator with pre-existing assumptions of autistic behavior erroneously based on media representations. This essay will examine literary and television representations of autistics working in university settings to argue that the nature of such portrayals negatively impacts the popular view of autistic scholars. Comedy is frequently used to highlight social awkwardness and other behavioral deviance, perpetuating Damian Milton’s double-empathy problem.

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From Margins To Mainstream: Embracing Neurodiverse Needs For An Inclusive Workplace, Ricardo Twumasi, Lewis Burton Dec 2024

From Margins To Mainstream: Embracing Neurodiverse Needs For An Inclusive Workplace, Ricardo Twumasi, Lewis Burton

Ought: The Journal of Autistic Culture

This article critically examines the dominance of neurotypical norms in contemporary workplaces and explores the potential for inclusive, neurodiverse workplaces to move from the margins to the mainstream. We offer a brief scoping review of the existing review literature on neurodivergence at work. Focusing on the more common neurominority differences such as autism spectrum, dyslexia and ADHD we apply the neurodiversity framework to challenge traditional notions of workplace "professionalism" and productivity. By synthesizing current research we propose constructive suggestions for creating truly neurodiverse work environments. Our analysis shows that the research community is calling out for long-term, scientific intervention trials …

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Learning To Be An Autistic Therapist: Personal Steps Towards An Autism-Affirming Psychotherapy, Sasha D. Strong Dec 2024

Learning To Be An Autistic Therapist: Personal Steps Towards An Autism-Affirming Psychotherapy, Sasha D. Strong

Ought: The Journal of Autistic Culture

How can Autistic therapists understand and support themselves, and how can this help them support their clients? In this paper, I recount my personal journey of healing and growth as an Autistic psychotherapist, 16 months after self-identification. Here is an overview of conceptual frameworks from #actuallyautistic authors, critical theory, queer theory, and social justice that I have found helpful. I also share some of the therapeutic and wellness approaches that have been important to me, including mindfulness and bodyfulness. Organic knowing has been pivotal for me in discerning between masking and aliveness, and regaining a choice around masking behaviors. This …

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Communicative Interventions For Autistic Employees In Academic Workplaces, Michaela De Meyer Dec 2024

Communicative Interventions For Autistic Employees In Academic Workplaces, Michaela De Meyer

Ought: The Journal of Autistic Culture

This essay provides an autoethnographic account of my experiences as an autistic employee in academia. By examining organizational communication literature on autism in the workplace, I identify some key issues that autistic employees face in academic workplaces. With research finding approximately 85% of autistic individuals are unemployed, and of those who are employed, only 6% are competitively employed in jobs that utilize their educational training and/or professional skill level, current cultural discourses around diversity, equity and inclusion initiatives in the workplace provide an opportunity to make organizational challenges for autistic employees more visible. By sharing my own experiences in the …

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Note From The Editors: On Work Spaces, Sonya Loftis Dec 2024

Note From The Editors: On Work Spaces, Sonya Loftis

Ought: The Journal of Autistic Culture

No abstract provided.

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Front Matter Dec 2024

Front Matter

Ought: The Journal of Autistic Culture

No abstract provided.

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Complete Issue: Vol. 12, No. 2, Stacy L. Creel, Ph.D. Dec 2024

Complete Issue: Vol. 12, No. 2, Stacy L. Creel, Ph.D.

SLIS Connecting

No abstract provided.

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Selection Of Spring And Fall 2024 Master’S Project Posters, Stacy L. Creel, Ph.D. Dec 2024

Selection Of Spring And Fall 2024 Master’S Project Posters, Stacy L. Creel, Ph.D.

SLIS Connecting

Students are required to create academic research posters on their capstone research project and present them in class. The following selection of the Master’s Project Capstone Posters are from LIS 695 in the Spring 2024 and Fall 2024.

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Website Accessibility In Mississippi Public Libraries, Jennifer Vance, Mlis Dec 2024

Website Accessibility In Mississippi Public Libraries, Jennifer Vance, Mlis

SLIS Connecting

The Americans With Disabilities Act was signed into law in 1990, significantly increasing the disabled community’s access to public life. Since then, life has branched out into digital and physical spaces. With this shift came the need to integrate accessibility considerations into web design, in the same way an architect would consider accessibility when drawing up plans for a new building. However, while buildings are usually designed by professionals, websites are often not. Libraries are no exception, as many may not have dedicated staff to design and maintain a website. In cases where they do have dedicated staff, they may …

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