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Articles 102661 - 102690 of 1826613
Full-Text Articles in Entire DC Network
The Relationship Between Solidarity And Job Satisfaction, Burnout, Work Stress, And Turnover Intention, Marcella R. Ronyak
The Relationship Between Solidarity And Job Satisfaction, Burnout, Work Stress, And Turnover Intention, Marcella R. Ronyak
Doctoral Dissertations and Projects
This quantitative study examined the relationship between supervisor-subordinate solidarity and subordinates’ level of job satisfaction among Indian Health Services (IHS) employees. Research has indicated that supervisor solidarity influenced job satisfaction, which allowed job satisfaction to serve as a mediator variable to negatively induce burnout and work stress and positively impact turnover intention. This study examined these variables using the Interpersonal Solidarity Scale © (Wheeless, 1976), Job Satisfaction Survey © (Spector, 1985), Maslach Burnout Inventory (Maslach & Jackson, 1981), Perceived Stress Scale (Cohen & Williamson, 1988), and Turnover Intention (adapted Wei-Yuan et al., 2023). Correlations were used to analyze relationships between …
Occupational Hazard Of Policing: A Phenomenological Study Of Moral Injury Among Law Enforcement Officers, Harley J. Lenart
Occupational Hazard Of Policing: A Phenomenological Study Of Moral Injury Among Law Enforcement Officers, Harley J. Lenart
Doctoral Dissertations and Projects
The concept of moral injury is relatively new, and most of the attention has been aimed at military veterans. Moral injury is perpetrating, failing to prevent, bearing witness to, or learning about acts that transgress deeply held moral beliefs and expectations. While awareness has increased in recent years, research on moral injury among law enforcement officers is limited. On average, during a 20-year career, police officers are exposed to 700 critical incidents, while average citizens may witness two. Law enforcement officers struggle with job burnout, depression, and suicide. Most law enforcement mental health studies focus on Posttraumatic Stress Disorder (PTSD), …
Products Of Their Inheritance And Experiences: The Political And Personal Influences On John Quincy And Louisa Catherine Adams, Claude Randall Brawner
Products Of Their Inheritance And Experiences: The Political And Personal Influences On John Quincy And Louisa Catherine Adams, Claude Randall Brawner
Doctoral Dissertations and Projects
John Quincy and Louisa Catherine Adams were important contributors to the American political landscape during a period of maturity. The Unites States was striving to solidify its independence within the dynamics of the global environment. The French Revolution and the resulting contingencies within the European nations had significant effect upon America. John Quincy and Louisa Catherine overcame significant ideological differences and each cooperated to provide essential differences within the global construct. Louisa Catherine began her marriage to John Quincy through an unexpected situation that was significantly expected and different from her childhood. The financial collapse of her father had significant …
Pentecostal Christian’S Influence On Marital Satisfaction And Longevity, Rebecca Burgess
Pentecostal Christian’S Influence On Marital Satisfaction And Longevity, Rebecca Burgess
Doctoral Dissertations and Projects
This research study aimed to explore the influence of Pentecostalism on marital satisfaction and longevity within the context of individuals who identify as Pentecostal Christians. By employing PENTECOSTALISM AND MARITAL SATISFACTION 3 phenomenology, the study sought to gain a deeper understanding of the experiences, perspectives, and beliefs of participants regarding the impact of Pentecostalism on their marriages. The research involves in-depth interviews with married individuals adhering to Pentecostal beliefs, examining their experiences and interpretations of how Pentecostal teachings and practices influence their marital satisfaction and relationship longevity. This study included a sample size of 10 participants, consisting of 5 married …
The Impact Of Covid-19 On Marital Satisfaction And Marital Resilience In Christian Couples, Melvinlyn Lovell Scott
The Impact Of Covid-19 On Marital Satisfaction And Marital Resilience In Christian Couples, Melvinlyn Lovell Scott
Doctoral Dissertations and Projects
This study examined the impact of the coronavirus, better known as COVID-19, on marital satisfaction and resilience in Christian marriages. Marital satisfaction and resilience are critical components of a successful marriage. Numerous studies have focused on marital satisfaction and resiliency (Carr & Kellas, 2018). However, little research focuses specifically on Christian married couples’ marital satisfaction and resilience during extraordinary conditions such as the recent pandemic, COVID-19. Even without a pandemic, marriages encounter internal and external stressors that can strengthen or destroy marriage. The primary goal of this quasi-experimental study using the interactionism theory was to (a) examine the impact of …
Direction Of Prayer And Marital Satisfaction, Jeffrey Deyel Brothers
Direction Of Prayer And Marital Satisfaction, Jeffrey Deyel Brothers
Doctoral Dissertations and Projects
The purpose of this correlational study was to assess the relationship between the constructs of prayer and marriage. Specifically, this study sought to answer the question of whether or not the direction of prayer, inward, outward, and upward was significantly correlated with marital satisfaction. Two hundred and one participants who were married, at least eighteen years of age, and who identified as Christian participated in the study. They completed a demographic questionnaire, the Prayer Thought Scale (PTS), and the ENRICH Couple Satisfaction Scale (CSS) online. Results indicated that there was no significant correlation between direction of prayer and marital satisfaction. …
Exploring The Role Of Teacher-Student Relationships In Inclusive Classrooms From The Lived Experiences Of High School Graduates With Disabilities, Mary D. Newman
Doctoral Dissertations and Projects
The purpose of this transcendental phenomenological study was to understand the lived experiences of special education students from inclusive classrooms who graduated from high school in a metropolitan city in Georgia. Academic mediation theory guided this research. The academic mediation theory identifies teacher-student relationships as critical in encouraging students to stay in school. The central research question was as follows: What are the lived experiences of high school students with disabilities in the inclusion classroom? This study was conducted using qualitative research methods. The researcher used a purposeful and criterion sampling method to identify 12 high school graduates with disabilities. …
The Masculine Perspective Of The Stigmatization Of Childlessness In Marriage In YorùBáLand: An Ile-Ife Phenomenological Study, Godwin Segun-George Olugbami
The Masculine Perspective Of The Stigmatization Of Childlessness In Marriage In YorùBáLand: An Ile-Ife Phenomenological Study, Godwin Segun-George Olugbami
Doctoral Dissertations and Projects
The purpose of this phenomenological study was to describe men's experiences with the stigmatization of childlessness in the context of marriage in Ile-Ife, Nigeria. The experience of childlessness as a universal phenomenon has been predominantly studied from the female perspective, and men are primarily neglected. The heteronormative ideal of women as 'mother/nurturer' is supported by only collecting women's fertility data in contrast to relatively suboptimal statistics in men's studies. This dissertation explores the view of ten African men set in the Yorùbá culture suffering from childlessness and its attendant stigmatization, mainly as a result of infertility. It provides in-depth interviews …
Clinton’S March: A Strategic And Logistical Study Of The Crown Forces’ March Through New Jersey In 1778, Colin Edward Zimmerman
Clinton’S March: A Strategic And Logistical Study Of The Crown Forces’ March Through New Jersey In 1778, Colin Edward Zimmerman
Doctoral Dissertations and Projects
This paper reexamines the British army's march through New Jersey in the summer of 1778, led by Sir Henry Clinton, challenging the traditional narrative that portrays Clinton’s movements as a mere retreat following the loss at the Battle of Monmouth. Instead, it argues that Clinton’s actions were part of a calculated strategy to provoke General George Washington’s Continental Army into a decisive engagement that could potentially end the Revolutionary War. By analyzing Clinton’s leadership decisions, logistical considerations, and the army’s experience during the march, this work reveals a more nuanced intention behind the British movements. The paper contends that Clinton’s …
Investigating The Correlation Between Racially Based Trauma And The Imposter Phenomenon In High-Achieving Black Women, Tarra Lynn Winfield Ray
Investigating The Correlation Between Racially Based Trauma And The Imposter Phenomenon In High-Achieving Black Women, Tarra Lynn Winfield Ray
Doctoral Dissertations and Projects
This study investigates the imposter phenomenon, racially based trauma, and how the two correlate among high-achieving Black women. High achieving for this writing refers to Black women who attend college or graduate school, those in professional positions that require a degree, advanced degree, or professional licensure (i.e., corporate executives, medical doctors, attorneys, mental health clinicians, etc.), and entrepreneurs. Many current studies have focused on the unique and complex experiences that high-achieving Black women face while working to achieve goals and gain success. Many of these women have experienced racially based trauma, and many endorse the simultaneous experiencing of the imposter …
Exploring The Influence Of Police Officers Lived Experiences On Implementing Community Oriented Policing Of Marginalized Populations, Herman "Tracy" Williams Iii
Exploring The Influence Of Police Officers Lived Experiences On Implementing Community Oriented Policing Of Marginalized Populations, Herman "Tracy" Williams Iii
Doctoral Dissertations and Projects
The oppositional relationship between the police and communities characterized as marginalized populations aptly describes an adversarial dynamic that hinders the effective implementation of guardian-focused, community-oriented policing. Fears of crime, claims of police bias, dehumanization, and perceptions of social disorder frequently breed socioeconomic decline in these communities. These conditions often contribute to citizens of marginalized communities viewing police officers as traditional policing warriors versus the roles of police as guardians who assist and protect the public. The problem is that the lack of cooperation and mutual distrust in interactions between the police and communities leads to external friction and internal organizational …
Care Providers Caring For Military Members Struggling With Grief, Clara Altagracia García
Care Providers Caring For Military Members Struggling With Grief, Clara Altagracia García
Doctoral Dissertations and Projects
This research aims to address the lack of grief support services for service members (SMs) and veterans, which affects them and the wider community. The mission is to uncover the needs of SMs and veterans and devise effective strategies to support them. The literature review will provide the foundation for the need for research and create a reasonable solution for a healthier grieving process for SMs. This research aims to determine how complicated grief goes undetected and how counseling can help SMs and veterans. The thesis project will impact the grief counseling process of others in this field and bring …
The Stigmatization Of Mental Health Illness And Mental Health Care Use Among Police Officers, Denia Aretta Roberts
The Stigmatization Of Mental Health Illness And Mental Health Care Use Among Police Officers, Denia Aretta Roberts
Doctoral Dissertations and Projects
This phenomenological study explored the stigma attached to police officers' mental health and how it affects their willingness to seek assistance. The research aimed to understand the role stigma plays in officers' mental health outcomes and investigated the systemic deterrents that prevent them from accessing the essential mental health services. Interviews conducted with former police officers disclosed that toughness and emotional restraint are cultural norms for perpetuating the cycle of silence, which many of the officers did in order to make it throughout their career without “repercussions”. The results underline the need to establish safe and non-judgmental conditions in police …
Citizen Complaints Against Police And Police Education Level: A Quantitative Analysis, Robert S. Swenszkowski
Citizen Complaints Against Police And Police Education Level: A Quantitative Analysis, Robert S. Swenszkowski
Doctoral Dissertations and Projects
Complaints against police officers result from citizens expressing dissatisfaction with police officers’ conduct, which is perceived as unjust. Citizen dissatisfaction with police services or the imposition of authority can lead to the belief that such authority is illegitimate and unjust, which can decrease levels of confidence and cooperation from citizens. Questions have long existed about the need for individuals to have some level of higher education to be employed as police officers. Yet, a consistent standardization for the minimum educational requirements for police officers in the United States has not been embraced. Research and theory suggest that higher education yields …
Exploring Joint Manifestations In Rasopathies: A Prospective Survey, Lavinia Dobrea
Exploring Joint Manifestations In Rasopathies: A Prospective Survey, Lavinia Dobrea
Doctoral Dissertations and Projects
RASopathies, a group of genetic diseases, affects approximately 1 in 1000 people worldwide. Despite advances documented in medical journals, there is limited understanding about the impact of various joint problems on activities of daily living (ADL) and quality of life (QOL) among those afflicted. This study was conducted, utilizing a qualitative phenomenological methodology, to better understand the lived experiences of people with RASopathies impacted by joint problems. Participants were selected from RASopathy communities by employing purposeful sampling to ensure population representation. Data was obtained through online surveys and virtual interviews. Thematic analysis was used to identify recurring themes, and data …
Parenting Strategies For Adult Abuse Victims, Sarah Davis
Parenting Strategies For Adult Abuse Victims, Sarah Davis
Doctoral Dissertations and Projects
The purpose of this phenomenological proposal is to describe adults with past childhood trauma’s parenting experiences in Missouri. Growing up in an abusive household, I saw how not to parent my children once I was older. Not everyone thinks this way. Children who grow up in an abusive household do not always develop resiliency. Due to these effects, the following proposal will look at how these adults are impacted when it comes to their parenting styles. Parenting is difficult, to begin with, let alone working through your issues. Generational abuse is a common occurrence. The main research question that will …
Technology-As-Instrument: A Case Study Of Undergraduate Student Experience With Daw Technology, Brian Coski
Technology-As-Instrument: A Case Study Of Undergraduate Student Experience With Daw Technology, Brian Coski
Doctoral Dissertations and Projects
Within the typical music appreciation class, diverse subsections of students exhibit varying levels of experience that can result in challenging inequities in engagement and comprehension. For those students with no background in playing an instrument or singing, musical ideas often need more context and perspective. Technology can present an opportunity for all students to explore the elements of music by utilizing music production software as a virtual instrument. In this study, the researcher utilized curriculum strategies specifically designed to foster deep musical connection through a technology-as-instrument approach. Through informal learning and the tools of music production, students visualized and interacted …
Red Herring: The Overstatement Of Soviet Power In The Early Cold War (1945-1953), Ronald R. Shaw
Red Herring: The Overstatement Of Soviet Power In The Early Cold War (1945-1953), Ronald R. Shaw
Doctoral Dissertations and Projects
The early Cold War (1945-1953) was a defining period for the 20th century, setting the grand strategic approach to the post-World War II era for the United States and Soviet Union. A common method employed by both sides was to overstate the power, capability, and aggression of the Soviet Union to enable grand strategic planning objectives. While acknowledging the tangible menace of communist expansion, President Truman used the illusion of an immediate Soviet existential threat to stoke fear, reject traditional isolationism, and facilitate American international engagement to protect free and open markets in Europe. Josef Stalin made use of American …
What Hath Jerusalem To Do With Chile: Towards An Evangelical Understanding Of The Enneagram And Its Usage For Spiritual Development, Wesley E. Scholtz
What Hath Jerusalem To Do With Chile: Towards An Evangelical Understanding Of The Enneagram And Its Usage For Spiritual Development, Wesley E. Scholtz
Doctoral Dissertations and Projects
Currently, it is estimated that the personality testing market is worth approximately $2 billion. The Church has expressed interest in understanding personality types through various testing methods. The Enneagram offers a possibly ancient method to help people understand who they are in a spiritual capacity, which can be an aid in connecting more closely with God. This dissertation addressed the research gap that exists within the current literature which is the lack of data concerning whether adults who are professional, ordained ministers are aware of, use, and may be skeptical of the Enneagram. The research method in this dissertation was …
A Philosophical, Theological, And Biblical Defense Of The Hebrew Concept Of Resurrection, Daniel M. Danciu
A Philosophical, Theological, And Biblical Defense Of The Hebrew Concept Of Resurrection, Daniel M. Danciu
Doctoral Dissertations and Projects
This project challenges the consensus view on the origins, hermeneutics, and validity of resurrection hope in Hebrew thought. It provides a scientific, philosophical, theological, and historical defense against minimalist and moderate perspectives. The case against the minimalists offers empirical evidence for an afterlife. It demonstrates that the Hebrew Bible discloses the afterlife and that early passages express the Hebrew concept of resurrection. New scientific data for near-death experiences, as well as the existence of the soul, which contradict specific neuroscience perspectives, support this argument. The practices such as necromancy and the resurrection of Jesus provide additional evidence for an afterlife, …
Racial Disparities Of Type 2 Diabetes Through Exercise: The Multi-Ethnic Study Of Atherosclerosis, Tong Xia, Roch A. Nianogo, Qingzhao Yu, Tamara Horwich, Preethi Srikanthan, Kosuke Inoue, Matthew Allison, Zuo-Feng Zhang, Karol E. Watson, Liwei Chen
Racial Disparities Of Type 2 Diabetes Through Exercise: The Multi-Ethnic Study Of Atherosclerosis, Tong Xia, Roch A. Nianogo, Qingzhao Yu, Tamara Horwich, Preethi Srikanthan, Kosuke Inoue, Matthew Allison, Zuo-Feng Zhang, Karol E. Watson, Liwei Chen
School of Public Health Faculty Publications
Introduction: Persistent racial and ethnic disparities exist for Type 2 diabetes in the U.S. Racial and ethnic minorities have a higher risk of Type 2 diabetes, and studies suggest that they engage in less exercise than White population. This study examined whether and to what degree racial differences in Type 2 diabetes were explained by exercise. Methods: Adults aged 45–84 years without Type 2 diabetes at baseline (2000–2002) were included from the Multi-Ethnic Study of Atherosclerosis cohort and followed through 2020. Associations between race and Type 2 diabetes were examined using multivariable Cox proportional hazard regression. The effects of exercise …
Exhibit 2 “Basement Iswp” 122 W. Daly St. Butte, Mt 59701 January 16, 2025 Database Residential Identifier: R-00845, Butte-Silver Bow Department Of Reclamation And Environmental Services
Exhibit 2 “Basement Iswp” 122 W. Daly St. Butte, Mt 59701 January 16, 2025 Database Residential Identifier: R-00845, Butte-Silver Bow Department Of Reclamation And Environmental Services
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Reflections On The Belfast/Good Friday Agreement, Alina Gamboa Combs
Reflections On The Belfast/Good Friday Agreement, Alina Gamboa Combs
Journal of Critical Global Issues
The 1998 Belfast Agreement, also known as the Good Friday Agreement (B/GFA), is considered a milestone for brokering peace and moving forward past the period known as the “Troubles” that plagued Northern Ireland for three decades (1961-1994). An overwhelming majority: 71 percent of the electorate in Northern Ireland (81 percent voter turnout) voted yes to the question, “Do you support the Agreement reached in the Multi-Party Talks?” giving the B/GFA and the subsequent legally binding British-Irish Agreement (BIA) strong public support. Since its signing, the B/GFA has been implemented in part. A key component, forming a Northern Ireland Assembly and …
Law Enforcement In Kentucky Schools - Student Interactions And Current Practices, Lee Ann Morrison
Law Enforcement In Kentucky Schools - Student Interactions And Current Practices, Lee Ann Morrison
Online Theses and Dissertations
This mixed-methods study investigates the role of school resource officers (SROs) in Kentucky and describes their interactions with students. This study aimed to provide a comprehensive understanding of how SROs interact with students and the implications of those interactions. The quantitative phase of the research involved a secondary analysis of student behavior violation data and the reported outcomes for students. Data indicated that student interaction with SROs did not lead to a significant student arrest rate. In the qualitative phase of the study, a focus group was conducted with school resource officers to explore their daily interactions with students. Qualitative …
Impact Of Transformational Leadership On Job Satisfaction Among Staff In Private Child Care Agencies, Carmin Marie Johnson
Impact Of Transformational Leadership On Job Satisfaction Among Staff In Private Child Care Agencies, Carmin Marie Johnson
Online Theses and Dissertations
Leadership styles and behaviors can impact employees' job performance and satisfaction. Murari and Mukherjee (2021), highlight that “building trust, clear vision, intellectual stimulation, inspirational motivation, self-awareness, transparency, individualized consideration, wisdom and knowledge, and congruent values” (p. 3612); are the faces of transformational leadership. Positive or negative behaviors can significantly affect job performance and total job satisfaction. The behavior of leadership has a significant impact on the success of employees and organizations. Leadership behavior affects many organizations, such as schools, community organizations, governmental organizations, and private agencies. Creswell (2012) describes correlational design as a form of research that uses data analysis …
The Positive Effects Of Audience Participation In Classic Literature, Joyelle Davis Braggs
The Positive Effects Of Audience Participation In Classic Literature, Joyelle Davis Braggs
Masters Theses
My thesis reviews the history of fan-fiction and how it plays a role in the world of literature, specifically classic literature. It focuses on Jane Eyre and Charlotte Bronte as well as the reasons why that storyline concluded the way it did. Also, I review the reasons why fans have decided to write their own versions of stories to either refresh or renew a character or storyline.
There is a brief history of fan-fiction and a simple summary of Jane Eyre. Included are examples of fan fiction that faced legal challenges both successfully and unsuccessfully. I have also shared my …
Witchcraft, Demons, And Spiritual Death: An Apologetic For The Bible's Prohibition Against Witchcraft, Joshua Dean Wrenn
Witchcraft, Demons, And Spiritual Death: An Apologetic For The Bible's Prohibition Against Witchcraft, Joshua Dean Wrenn
Masters Theses
This paper attempts to apologetically defend the Bible's intolerance against witchcraft and other related activities that are prohibited in the Old Testament. It does so by showing that Witchcraft and other related activities gets one involved with demonic entities. It shows how demonic entities are deceitful, and how they are actually the ones behind the power of witchcraft. The paper starts by studying the history of ancient witchcraft, which is something that is useful for understanding the witchcraft of today. It then builds a profile of demons. The paper shows what demons physically do and what they attempt to get …
Assessment, Decision, Adaptation, Production, Topical Experts-Integration, Training, And Testing (Adapt-Itt) Framework To Tailor Evidence-Based Posttraumatic Stress Disorder Treatment For People With Hiv To Enhance Engagement And Adherence: Qualitative Results From A Feasibility Randomized Controlled Trial, Cristina M. Lopez, Angela D. Moreland, Stephanie Amaya, Erin Bisca, Christin Mujica, Tayler Wilson, Nathaniel Baker, Lauren Richey, Allison Ross Eckard, Patricia A. Resick, Steven A. Safren, Carla Kmett Danielson
Assessment, Decision, Adaptation, Production, Topical Experts-Integration, Training, And Testing (Adapt-Itt) Framework To Tailor Evidence-Based Posttraumatic Stress Disorder Treatment For People With Hiv To Enhance Engagement And Adherence: Qualitative Results From A Feasibility Randomized Controlled Trial, Cristina M. Lopez, Angela D. Moreland, Stephanie Amaya, Erin Bisca, Christin Mujica, Tayler Wilson, Nathaniel Baker, Lauren Richey, Allison Ross Eckard, Patricia A. Resick, Steven A. Safren, Carla Kmett Danielson
School of Medicine Faculty Publications
BACKGROUND: Individuals with co-occurring posttraumatic stress disorder (PTSD) and HIV are at high-risk for negative HIV-related outcomes, including low adherence to antiretroviral therapy, faster disease progression, more hospitalizations, and almost twice the rate of death. Despite high rates of PTSD in persons with HIV (PWH) and poor HIV-related health outcomes associated with PTSD, an effective evidence-based treatment for PTSD symptoms in PWH does not exist. OBJECTIVE: This study aimed to describe the adaptation and theater testing of an evidence-based intervention designed for people with co-occurring PTSD and HIV. METHODS: The Assessment, Decision, Adaptation, Production, Topical experts-integration, Training, and Testing (ADAPT-ITT) …
Associations Between Deficit Accumulation Frailty And Baseline Markers Of Lifestyle In The Us Pointer Trial, Samuel N Lockhart, Sarah E Tomaszewski Farias, Maryjo L Cleveland, Christy C Tangney, Lucia Crivelli, Heather M Snyder, Michele K York, Laura D Baker, Rachel A Whitmer, Rena R Wing, Katelyn R Garcia, Kathryn E Callahan
Associations Between Deficit Accumulation Frailty And Baseline Markers Of Lifestyle In The Us Pointer Trial, Samuel N Lockhart, Sarah E Tomaszewski Farias, Maryjo L Cleveland, Christy C Tangney, Lucia Crivelli, Heather M Snyder, Michele K York, Laura D Baker, Rachel A Whitmer, Rena R Wing, Katelyn R Garcia, Kathryn E Callahan
Faculty, Staff and Students Publications
BACKGROUND: Multidomain lifestyle interventions may have the potential to slow biological aging as captured by deficit accumulation frailty indices. We describe the distribution and composition of the 49-component frailty index developed by the U.S. POINTER clinical trial team of investigators and assess its cross-sectional associations with sociodemographic factors and markers chosen to be representative of behaviors targeted by the trial's multidomain interventions.
METHODS: We draw baseline data from the 2 111 volunteers enrolled in U.S. POINTER who were ages 60-79 years and at increased risk for cognitive decline. Frailty components were grouped into 9 domains. Associations that frailty index scores …
Sex Differences In Response To Diet Enriched With Glutathione Precursors In The Aging Heart, Marta L Fiorotto, Alexander Saltzman, Antrix Jain, Joann Trial, George E Taffet, Katarzyna A Cieslik
Sex Differences In Response To Diet Enriched With Glutathione Precursors In The Aging Heart, Marta L Fiorotto, Alexander Saltzman, Antrix Jain, Joann Trial, George E Taffet, Katarzyna A Cieslik
Faculty, Staff and Students Publications
Common features of the aging heart are dysregulated metabolism, inflammation, and fibrosis. Elevated oxidative stress is another hallmark of cardiac aging that can exacerbate each of these conditions. We hypothesize that by increasing natural antioxidant levels (glutathione), we will improve cardiac function. Twenty-one-month-old mice were fed glycine and N-acetyl cysteine (GlyNAC; glutathione precursors)-supplemented or control diets for 12 weeks. Heart function was monitored longitudinally, and the exercise performance was determined at the end of the study. We found that the GlyNAC diet was beneficial for old male but not old female mice, leading to an increase of Ndufb8 expression (a …