Digital Commons Network^™

Beyond Binary Judgments: A Neutrosophic Framework For Evaluating News Writing Quality Through Common And Uncommon Meaning, Xiaochun Yuan

Neutrosophic Sets and Systems

No abstract provided.

A Hybrid Magdm Approach Of Neutrosophic Topsis Linmap Method For Developing Enterprise Selection Criteria, G. Tamilarasi, S. Paulraj, M.Sivanandha Saraswathy, Thanuja T S

Neutrosophic Sets and Systems

No abstract provided.

Integrating Treesoft And Hypersoft Paradigms Into Urban Elderly Care Evaluation: A Comprehensive N-Superhypergraph Approach, Yan Cao

Neutrosophic Sets and Systems

No abstract provided.

A Recursive Indetermtree Soft Set (Rit-Soft Set) For Dynamic And Uncertain Performance Evaluation In College Competitive Sports, Hai Yang, Cuijuan Lin

Neutrosophic Sets and Systems

No abstract provided.

A Novel Metasoft Tree-Cognitive Set Model For Evaluating Criminal Litigation Efficiency Under Artificial Intelligence Ecosystems, Yuanyuan Meng, Jing Cai

Neutrosophic Sets and Systems

No abstract provided.

Topsis Method-Based Decision-Making Model For Bipolar Quadripartitioned Neutrosophic Environment, G. Muhiuddin, Mohamed E. Elnair, Satham Hussain S, Durga Nagarajan

Neutrosophic Sets and Systems

No abstract provided.

A Neutrosophic Twofold Algebra-Based Framework For Evaluating Practical Teaching Quality In Fashion Design And Technology Education, Guiling Ba

Neutrosophic Sets and Systems

No abstract provided.

A Neutrostructural Methodology For Empowering New-Quality Productivity Toward High-Quality Development In The Smart Elderly Care Industry, Xiaoqin Yang

Neutrosophic Sets and Systems

No abstract provided.

Muirhead Mean Operators In Quadripartitioned Single-Valued Neutrosophic Sets For Multi-Criteria Decision-Making With Indeterminate Information, Anitha P, Chitra Devi P, Satham Hussain, Durga Nagarajan, Said Broumi, Sankar Sahoo, Hossein Rashmanlou

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic N-Superhypernetwork: A New Approach For Evaluating Short Video Communication Effectiveness In Media Convergence, Shouxian Zhu

Neutrosophic Sets and Systems

No abstract provided.

Weighted Indetermsoft Set For Prioritized Decision-Making With Indeterminacy And Its Application To Green Competitiveness Evaluation In Equipment Manufacturing Enterprises, Wei Wei, Pingting Peng

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Sets And Systems, Vol. 85,2025, Florentin Smarandache, Mohamed Abdel-Basset, Maikel. Leyva Vazquez

Neutrosophic Sets and Systems

No abstract provided.

Evidence-Based Shared Agendas For Scholarship On Teaching With Primary Sources: Reflections On A Bibliometric Analysis, Jen Hoyer, Anne Bahde

Publications and Research

This article explores how scholarship about teaching with primary sources (TPS) has evolved over time and what future directions past work might suggests. Using bibliometric analysis and visualization tools, we examined how TPS work has grown; what fields and disciplines focus on this work; key themes and issues; and what scholarship has been influential to the field. These insights led to reflections on disconnects across the field, considerations for publishing about TPS, and the potential of pedagogical standards and guidelines. Finally, this article concludes with recommendations on how this analysis points to possibilities for shared education, space, conversation, and products.

Kimball Hall, 1970: Collective Organizing Through Print Production, Jen Hoyer

Publications and Research

This article examines the May 1970 occupation of Kimball Hall, a university administrative building at New York University, and specifically of its basement printshop. The group that came together in this space referred to itself as the Kimball Commune; they used university equipment and resources to print material in support of the strike and related movements, and they invited students, activists, and the general public to come into the printshop and produce material with them. I demonstrate how the Kimball Commune provides a concrete example of how a collaborative radical printing project isn’t just about creating alternative media. It also …

The Effects Of Extreme Weather On Rural Transportation Infrastructure And Crop Prices Along The Lower Mississippi River, James Mitchell, Hunter D. Biram

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Extreme weather events are worsening the fragile rural infrastructure in the United States, impacting trade flows of agricultural products. The Mississippi River, vital for transporting agricultural commodities, reached historic lows during the 2022 and 2023 fall harvests, increasing transportation costs and lowering crop prices. This paper estimates the cost of these drought events by analyzing Arkansas soybean basis data and Mississippi River stream gauge data. Low river levels significantly weaken soybean prices, with the impact being a function of a grain market's distance to a river port. Findings have implications for public policy investment in rural infrastructure and risk management …

Long Akap18 Isoforms Anchor Ubiquitin Specific Proteinases And Coordinate Calcium Reuptake At The Sarcoplasmic Reticulum, Taeyeop Park, Katherine Forbush, Yong Li, Oscar Vivas, Kacey J Rosenthal, Jerome Falcone, Cassandra J Wong, James E Bruce, Claudia Moreno, Carmen W Dessauer, John D Scott

Faculty, Staff and Student Publications

Subcellular targeting of signaling enzymes influences where and when various modes of intracellular communication operate. Macromolecular complexes of signal transduction and signal termination elements favor reversible control of repetitive processes. This includes adrenergic stimulation of excitation–contraction coupling in the heart. Long isoforms of A-kinase anchoring protein 18 (AKAP18γ and δ) modulate this process via regulation of calcium uptake into the sarcoplasmic reticulum through the Ca2+ATPase 2a (SERCA2a). AKAP18 proximity-proteomic screening in cardiomyocytes identifies networks for protein kinase A (PKA) and ubiquitin-specific proteinases (USPs). A 2′phosphoesterase domain on AKAP18 interfaces with the USP4 isoform at the Z bands of sarcomeres. PKA …

Image-Based Mandibular And Maxillary Parcellation And Annotation Using Computed Tomography (Impact): A Deep Learning-Based Clinical Tool For Orodental Dose Estimation And Osteoradionecrosis Assessment, Laia Humbert-Vidan, Austin H Castelo, Renjie He, Lisanne V Van Dijk, Dong Joo Rhee, Congjun Wang, He C Wang, Kareem A Wahid, Sonali Joshi, Parshan Gerafian, Natalie West, Zaphanlene Kaffey, Sarah Mirbahaeddin, Jaqueline Curiel, Samrina Acharya, Amal Shekha, Praise Oderinde, Alaa M S Ali, Andrew Hope, Erin Watson, Ruth Wesson-Aponte, Steven J Frank, Carly E A Barbon, Kristy K Brock, Mark S Chambers, Muhammad Walji, Katherine A Hutcheson, Stephen Y Lai, Clifton D Fuller, Mohamed A Naser, Amy C Moreno, Opc-Survivor Program, Md Anderson Head And Neck Cancer Symptom Working Group

Faculty, Staff and Student Publications

Background and purpose: Accurate delineation of orodental structures on radiotherapy computed tomography (CT) images is essential for dosimetric assessment and dental decisions. We propose a deep-learning (DL) auto-segmentation framework for individual teeth and mandible/maxilla sub-volumes aligned with the ClinRad osteoradionecrosis staging system.

Materials and methods: Mandible and maxilla sub-volumes were manually defined on simulation CT images from 60 clinical cases, differentiating alveolar from basal regions; teeth were labelled individually. For each task, a DL segmentation model was independently trained. A Swin UNETR-based model was used for mandible sub-volumes. For smaller structures (e.g., teeth and maxilla sub-volumes) a two-stage model first …

The Evolution Of Multidisciplinary Head And Neck Cancer Treatment, Kevin J Contrera, Pooja D Reddy, Vanessa Helou, Jeffrey N Myers, Heath D Skinner, Renata Ferrarotto, Eugene N Myers

Faculty, Staff and Student Publications

Objective: The management of head and neck squamous cell carcinoma (HNSCC) has substantially changed over the past two centuries. This review explores the historical progression of HNSCC management focusing on the multidisciplinary treatment paradigm.

Data sources: This review synthesizes data from historical and current clinical trials, books, scientific reports, public documents, and other written material relevant to HNSCC management.

Review methods: Historical review.

Results: Although surgery was initially the only treatment available, radiation, chemotherapy, and immunotherapy have expanded the treatment landscape for HNSCC. Despite continuous evolution, modern treatment of HNSCC remains rooted in a multidisciplinary, personalized approach. This review highlights …

Feasibility Of Monte Carlo-Based Patient-Specific Quality Assurance In 15 Tesla Magnetic Resonance-Guided Online Adaptive Radiotherapy: A Multi-Institutional Study, Ruiqi Li, Yao Zhao, Jingying Lin, Tsuicheng Chiu, Weiguo Lu, Jinzhong Yang, Mu-Han Lin

Faculty, Staff and Student Publications

Introduction: To evaluate the feasibility of Monte Carlo (MC)-based patient-specific quality assurance (PSQA) for MR-guided online adaptive radiotherapy and to explore the potential to eliminate the post-delivery measurement-based PSQA.

Material and methods: A total of 113 cases from two institutions, treated on MR-Linac machines, were included in the study. A customized GPU-accelerated, Monte Carlo-based secondary dose verification software (ART2Dose) was developed and integrated into the QA workflow, accounting for a 1.5 Tesla magnetic field. PSQA included ArcCheck (AC) delivery QA and online MC calculation-based QA. Reference plans underwent offline validation with AC and MC, while adapt-to-shape (ATS) plans were processed …

Blood Bacterial Dna Signatures In A Prospective Cohort Of Patients With Masld Cirrhosis, Suet-Ying Kwan, Lillian I Dolapchiev, Caren I Sanchez, Tiffany L Calderone, Jessica I Sanchez, Megha B Bhongade, Ahmed El Sabagh, Darrel W Cleere, Nakul Gupta, Prasun K Jalal, David W Victor, Laura Beretta

Faculty, Staff and Student Publications

Background: Predictive biomarkers are needed to identify individuals with metabolic dysfunction-associated steatotic liver disease (MASLD), at high risk for HCC. Our study aimed to determine whether the detection of circulating bacterial DNA could be associated with HCC development in MASLD patients with liver cirrhosis.

Methods: We developed a multicenter prospective cohort of patients with cirrhosis undergoing surveillance for HCC by contrast-enhanced magnetic resonance imaging. In a nested cohort study, we performed 16S rRNA sequencing of cell-free DNA extracted from 343 longitudinal plasma samples collected from 151 MASLD patients with cirrhosis. Among the 151 patients, 25 developed HCC during follow-up.

Results: …

A Method For Sensitivity Analysis Of Automatic Contouring Algorithms Across Different Contrast Weightings Using Synthetic Magnetic Resonance Imaging, Lucas Mccullum, Zayne Belal, Warren Floyd, Alaa Mohamed Shawky Ali, Natalie West, Samuel Mulder, Yao Ding, Jiaofeng Xu, Dan Thill, Nicolette O'Connell, Joseph Stancanello, Kareem A Wahid, David T Fuentes, Ken-Pin Hwang, Clifton D Fuller

Faculty, Staff and Student Publications

Background and purpose: A majority of institution-specific automatic magnetic resonance imaging (MRI)-based contouring algorithms utilize one contrast-weighting (i.e., T2-weighted), however their performance within this contrast-weighting (i.e., across different repetition time, TR, and echo time, TE) is under-investigated and poorly understood. The purpose of this study was to develop a method to evaluate the robustness of automatic contouring algorithms to varying MRI contrast-weightings.

Materials and methods: One healthy volunteer and one patient were scanned using the multi-delay multi-echo (MDME) scan on a 3T MRI. The parotid and submandibular glands in these subjects were contoured using an automatic contouring algorithm trained on …

Technical Development And In Silico Implementation Of Syntheticmr In Head And Neck Adaptive Radiation Therapy: A Prospective R-Ideal Stage 0/1 Technology Development Report, Lucas Mccullum, Samuel L Mulder, Natalie A West, Robert Aghoghovbia, Alaa Mohamed Shawky Ali, Hayden Scott, Travis C Salzillo, Yao Ding, Alex Dresner, Ergys Subashi, Dan Ma, R Jason Stafford, Ken-Pin Hwang, Clifton D Fuller

Faculty, Staff and Student Publications

Background: SyntheticMR has the capability of generating quantitative relaxometry maps and synthetic contrast-weighted MRI images in rapid acquisition times. Recently, it has gained attention in the diagnostic community, however, no studies have investigated its feasibility on the MR-Simulation or MR-Linac systems, especially as part of the head and neck adaptive radiation oncology workflow.

Purpose: Demonstrating its feasibility will facilitate rapid quantitative biomarker extraction, which can be leveraged to guide adaptive radiation therapy decision making.

Methods: Two phantoms, two healthy volunteers, and one patient were scanned using SyntheticMR on the MR-Simulation and MR-Linac devices with scan times between 4 to 6 …

First-In-Human Phase 1 Study Of Khk2455 Monotherapy And In Combination With Mogamulizumab In Patients With Advanced Solid Tumors, Timothy A Yap, Olivier Rixe, Capucine Baldini, Ursa Brown-Glaberman, Sergey Efuni, David S Hong, Christophe Massard, Jameel Muzaffar, Andreea Varga, Emrullah Yilmaz, Yuta Ikawa, Lisa H Shiue, Yi Liu, Matthew W Hruska, Henry Zhao, Akihiro Tokunaga, Solmaz Sahebjam

Faculty, Staff and Student Publications

Background: Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme that degrades tryptophan (Trp) to kynurenine (Kyn), which suppresses effector T cells and reduces antitumor activity. KHK2455 is a long-acting selective IDO1 inhibitor that blocks the heme component of the IDO holoenzyme. Mogamulizumab is a humanized immunoglobulin G1 monoclonal antibody targeting CCR4. KHK2455 + mogamulizumab demonstrated enhanced antitumor activity in preclinical studies, which led to a first-in-human, two-part, multicenter, open-label, phase 1, dose-escalation, cohort-expansion trial (ClinicalTrials.gov identifier NCT02867007) evaluating the safety/tolerability, pharmacokinetics, and IDO1 activity of KHK2455 alone and in combination with mogamulizumab in patients with treatment-refractory advanced solid tumors. …

Dynamic Contrast-Enhanced Mri Processing Comparison For Distinguishing True Progression From Pseudoprogression In High-Grade Glioma, Ahmad Amer, Shehbaz Ansari, Apollo Krayyem, Suprateek Kundu, Swapnil Khose, Halyna Pokhylevych, Susana Calle, Chirag B Patel, Zixi Yang, Ho-Ling Anthony Liu, Jason M Johnson

Faculty, Staff and Student Publications

Background: Treatment-related changes may occur due to radiation and temozolomide in glioblastoma and can mimic tumor progression on conventional MRI. DCE-MRI enables quantification of the extent of blood-brain barrier (BBB) disruption, providing information about areas of suspicious postcontrast T1 enhancement. We compared DCE-MRI processing methods for distinguishing true disease progression from pseudoprogression in high-grade gliomas (HGGs).

Methods: We identified 110 patients with HGG treated with surgery and chemoradiation who underwent DCE-MRI to further interrogate areas of new/increasing enhancement. All patients had confirmatory surgery/biopsy with pathology-confirmed progression or pseudoprogression. Scans were performed at 3T and analyzed using nordicICE. The MCA, SSS, …

Supporting Administrative Time For Advanced Practitioners: A Comprehensive Approach, Merdith Beaton, Andrea Edwards, Wendy Vogel, Haleigh Mistry, Lisa Kottschade, Sara Toth, David Johnson, Heather Koniarczyk

Faculty, Staff and Student Publications

Advanced practitioners (APs), including nurse practitioners (NPs), physician assistants (PAs), clinical nurse specialists, and pharmacists, are pivotal in health care. Despite their critical role, record numbers of APs are leaving the profession, primarily due to poor work-life balance, which contributes to burnout and high turnover rates. This article explores the impact of administrative time on AP job satisfaction and retention, drawing from recent surveys and case studies. Findings indicate that dedicated administrative time significantly enhances job satisfaction and reduces burnout, with data showing that APs with administrative time are less likely to leave their roles. The Advanced Practitioner Society for …

The Methane Clumped Isotope Signatures Of The Acetoclastic And Methylotrophic Methanogenesis Pathways, Mia L. Thompson

Dartmouth College Master’s Theses

Methane is a potent greenhouse gas and critical energy source for the global economy. Atmospheric methane concentrations play a critical role in global warming, while mitigating methane emissions may provide route to short-term reduction of warming effects. In order to track rates and sources of emissions, it is first necessary to understand the sources and sinks of methane; yet, there are challenges in distinguishing abiotic (water/rock), thermogenic, and biogenic methane. Traditional approaches of using the bulk isotopes of carbon (δ¹³C) and hydrogen (δD) of methane have limitations due to overlapping signatures and sensitivity to substrate isotope composition. In …

Quality Of Life Outcomes Following Total Temporomandibular Joint Replacement: A Systematic Review Of Long-Term Efficacy, Functional Improvements, And Complication Rates Across Prosthesis Types, Luis Eduardo Almeida, Samuel Zammuto, Louis G. Mercuri

School of Dentistry Faculty Research and Publications

Introduction:

Total temporomandibular joint replacement (TMJR) is a well-established surgical solution for patients with severe TMJ disorders. It aims to relieve chronic pain, restore jaw mobility, and significantly enhance quality of life. This systematic review evaluates QoL outcomes following TMJR, analyzes complication profiles, compares custom versus stock prostheses, explores pediatric applications, and highlights technological innovations shaping the future of TMJ reconstruction.

Methods:

A systematic search of PubMed, Embase, and the Cochrane Library was conducted throughout April 2025 in accordance with PRISMA 2020 guidelines. Sixty-four studies were included, comprising 2387 patients. Results: Primary outcomes assessed were QoL improvement, pain reduction, and …

Racial And Ethnic Factors And Opioid Use Disorder Treatment After An Emergency Department Visit, Edouard Coupet Jr., Marek C. Chawarski, Kavari Hercules, Joseph L. Williams, Alexandra Murphy Ward, Patricia H. Owens, David A. Fiellin, Kathryn F. Hawk, Shara H. Martel, Gail D'Onofrio

Student Publications

Importance: There are racial and ethnic disparities in opioid use disorder (OUD) treatment engagement during and after emergency department (ED) encounters.

Objective: To identify patterns of barriers and facilitators to treatment engagement after an ED visit among Black, Hispanic, and White individuals with OUD.

Design, setting, and participants: This qualitative study was conducted from June 2023 to May 2024 using in-depth semistructured individual telephone interviews. Participants with OUD were previously enrolled in a multisite study comparing 2 formulations of buprenorphine in ED patients with untreated OUD on treatment engagement.

Exposures: A diagnosis of moderate-to-severe OUD and a visit to an …

Functional Assays In Drosophila Facilitate Classification Of Variants Of Uncertain Significance Associated With Rare Diseases, Jung-Wan Mok, Shelley B Gibson, Haley A Dostalik, Shinya Yamamoto

Faculty, Staff and Students Publications

Individuals living with rare diseases often undergo a frustrating and expensive diagnostic odyssey. Clinical geneticists who analyze exome or genome sequencing data from rare disease patients often encounter a list of variants of uncertain significance (VUS) in known disease-causing genes or rare variants in genes of uncertain significance (GUS) that are difficult to interpret, even with the integration of the latest bioinformatic tools. In this Perspective, we review how studies using the fruit fly Drosophila melanogaster have facilitated rare disease diagnosis by uncovering the clinical relevance of GUS and classifying rare variants into specific allelic categories (loss-of-function or gain-of-function, Muller's …

Faculty Perceptions Of Diversity And Its Impact On Postsecondary Student Success: A Case Study In A Business School, Andrea Camargo, Harika Rao

Faculty and Staff Publications & Presentations

This case study investigates the way in faculty perceives the function of diversity in molding student success and institutional inclusiveness under a business school’s context. Conducting a mixed-methods survey of faculty, the study examines the question, does diverse faculty representation influence student retention, classroom engagement, and academic performance? Findings reveal robust agreement amongst faculty that diversity makes learning environments more inclusive, promotes student well-being and creates supportive mentor relationships with desirable influence to student persistence and success. The qualitative responses show the implication of culturally responsive teaching practices and inclusive faculty–student relationships, especially to underrepresented students. Although this assumes an …