Digital Commons Network^™

Use Of An Electronic Medication Management Application To Support Pharmacists Review To Optimise Medicines In Residential Aged Care (Prompt-Rc): A Study Protocol For A Parallel Cluster Randomised Controlled Trial, Amy Theresa Page, Dee Mangin, Hend Almutairi, Esa Y.H. Chen, Kenneth Lee, Nagham Ailabouni, Jacinta Johnson, Kathleen Potter, Nahal Mavaddat, Rhonda Marise Clifford, Elton Lobo, Loretta Baldassar, Liza Seubert, Dennis Petrie, Kate Wang, Sarah Hosking, Jenny Tasker, Christopher Etherton-Beer

Research outputs 2022 to 2026

Introduction Most older adults living in residential aged care facilities (RACFs) have at least one marker of potentially suboptimal prescribing. Pharmacists play a crucial role in medication management, with their effectiveness enhanced by using computerised decision support tools. The Pharmacists Review to Optimise Medicines in Residential Aged Care (PROMPT-RC) study aims to optimise medicine use by providing pharmacists in RACFs with an electronic medicine management app with integrated decision support (AusTAPER App/Pathway) to use as part of medication reviews they undertake. Methods and analysis The PROMPT-RC study is a parallel cluster randomised controlled trial design involving Australian RACFs. It will …

Aspen Impedes Wildfire Spread In Southwestern United States Landscapes, Matthew P. Harris, Jonathan D. Coop, Jared A. Balik, Jessika R. Mcfarland, Sean A. Parks, Camille S. Stevens-Rumann

Aspen Bibliography

Aspen (Populus tremuloides) forests are generally thought to impede fire spread, yet the extent of this effect is not well quantified in relation to other vegetation types. We examined the influence of aspen cover on interpolated daily fire spread rates, the relative abundance of aspen at fire perimeters versus burn interiors, and whether these relationships shifted under more fire-conducive atmospheric conditions. Our study incorporated 314 fires occurring between 2001 and 2020 in the southwestern United States and a suite of gridded vegetation, topography, and fire weather predictor variables. We found that aspen slows fire progression: as aspen cover …

Vaccination Against Influenza Viruses Annually: Renewing Or Narrowing The Protective Shield?, Hanover C Matz, Ali H Ellebedy

2020-Current year OA Pubs

Annual vaccines are recommended for the seasonal influenza virus. While yearly updates to the vaccine are necessary due to the constant evolution of influenza viruses, some studies have suggested repeat vaccination may result in a reduction in vaccine effectiveness in subsequent years. This review examines the available evidence that repeated annual influenza virus vaccination may have effects on future vaccine responses, and it synthesizes the available data with studies that may indicate potential immunological mechanisms underlying these effects. The goal is to examine the available literature to determine whether these mechanisms can be subverted to improve seasonal influenza virus vaccine …

Loss Of Intracellular Fgf14 (Ifgf14) Increases Excitability Of Mature Hippocampal Pyramidal Neurons, Joseph L Ransdell, Yarimar Carrasquillo, Marie K Bosch, Rebecca L Mellor, David M Ornitz, Jeanne M Nerbonne

2020-Current year OA Pubs

Mutations in FGF14, which encodes intracellular fibroblast growth factor 14 (iFGF14), have been linked to spinocerebellar ataxia type 27 (SCA27), a multisystem disorder associated with deficits in motor coordination and cognitive function. Mice lacking iFGF14 (Fgf14-/-) display similar phenotypes, and we have previously shown that the deficits in motor coordination reflect reduced excitability of cerebellar Purkinje neurons, owing to a hyperpolarizing shift in the voltage-dependence of voltage-gated Na+ (Nav) current steady-state inactivation. Here, we present the results of experiments designed to test the hypothesis that loss of iFGF14 also attenuates the intrinsic excitability of mature hippocampal pyramidal neurons. Current-clamp recordings …

Disruption Of A Side Portal Pathway Permits Closed-State Inactivation By Bk Β Subunit N Termini, Yu Zhou, Xiao-Ming Xia, Christopher J Lingle

2020-Current year OA Pubs

Cytosolic N termini of several BK channel β regulatory subunits mediate rapid inactivation. However, in contrast to Kv channels, inactivation does not occur via a simple, open-channel block mechanism, but involves two steps, an association step in which ion permeation is maintained (O*), then followed by inactivation (I). To produce inactivation, BK β subunit N termini enter the central cavity through a lateral entry pathway ("side portal") separating the transmembrane pore-gate domain and cytosolic gating ring. Comparison of BK conformations reveals an aqueous pathway into the central cavity in the open structure, while in the closed structure, three sequential basic …

Validation Of A 5-Item Tool To Measure Parent Assessment Of Clinician Compassion During Pediatric Visits., Eena S Lin, Alexandra Seabury, Mohammadsadegh Mikaeili, Joshua Bosire, Anthony Mazzarelli, Michael B. Roberts, Stephen Trzeciak, Brian W Roberts, Rafat Ahmed

PCOM Scholarly Works

Our objective was to validate a 5-item compassion measurement tool as a reliable measure of patient assessments of clinician compassion in the pediatric outpatient setting. We completed a cross-sectional study in a U.S. academic healthcare system consisting of six pediatric clinics between February and September 2023. We adapted the original 5-item tool to elicit responses regarding the pediatric patient. The measure was disseminated with the Clinician and Group Consumer Assessment of Healthcare Providers and System (CG-CAHPS) survey. We included patients aged < 18 years old who had an outpatient clinic visit and had a parent complete the CG-CAHPS survey. Validity testing of the 5-item tool was performed using confirmatory factor analysis. Internal reliability was tested using Cronbach's α, and convergent validity with overall provider rating questions from the CG-CAHPS survey was evaluated using Spearman correlation. We analyzed 640 responses. The median (interquartile range) patient age was 8 (3-13) years, and 47% of patients were female. Sixty-one percent of patients were White/Caucasian and 25% were Black/African American. Confirmatory factor analyses found a good fit. The compassion measure demonstrated good internal consistency (α = 0.97) and convergent validity with overall provider rating (r_s = 0.63 (95% confidence interval 0.56-0.70)) but reflected a patient experience domain distinctly different from what is currently …

A Survey On Security Applications With Smartnics: Taxonomy, Implementations, Challenges, And Future Trends, Serigo Elizalde, Ali Alsabeh, Ali Mazloum, Samia Choeiri, Elie Kfoury, Jose Gomez, Jorge Crichigno

Faculty Publications

Over the last decade, network applications have grown exponentially, demanding high-speed interconnects. Unfortunately, chip manufacturers are approaching the upper limits of silicon-based computing with slow improvements in computational performance and energy efficiency. This trend has forced the industry to shift paradigms, moving from monolithic architectures to heterogeneous, domain-specific designs. Moreover, the ever-evolving threats compromise digital services and demand more scalable and flexible solutions to ensure service continuity in production networks. Smart Network Interface Cards (SmartNICs) are a product of this new paradigm, integrating domain-specific engines and general-purpose cores to offload various network infrastructure tasks, including those related to security. This …

Low Premorbid Iq May Exacerbate The Cognitive Effects Of Apolipoprotein Ε4 (Apoe Ε4): A Multi-Ethnic Cross-Sectional Study From Habs-Hd, Lubnaa B. Abdullah, Zhengyang Zhou, Ney Alex Alliey, Robert Barber, James Hall, Sid O’Bryant

Psychological Science Faculty Publications

Introduction: Apolipoprotein allele 4 (APOE ε4) is associated with lower IQ scores during childhood and adolescence, but the influence of APOE ε4 and low IQ on late-life cognition is unknown. This study examines the association between APOE ε4 and cognitive outcomes based on premorbid intellectual ability (pIQ) and ethnic background.

Methods: Participants were drawn from the Health & Aging Brain Study–Health Disparities (HABS-HD), categorized by low (z ≤ −2.00) or average (z = 0.00 ± 1.00) pIQ based on word reading scores. Statistical analyses were conducted to evaluate whether APOE ε4 was associated with the cognitive domains of …

Consideration Of Patient Phenotypes In Geographic Atrophy Due To Age-Related Macular Degeneration, Rishi P Singh, Christina Y Weng, John W Kitchens, Jaclyn Quilantan, Roy Schwartz, Caroline R Baumal, Roger A Goldberg

Faculty, Staff and Students Publications

Geographic atrophy (GA) is a form of advanced age-related macular degeneration (AMD) affecting approximately 1 million people in the USA and 5 million globally. In this review, retinal imaging techniques used for diagnosis and monitoring progression of GA in AMD, and the risk factors associated with the development and progression of GA are summarised. To familiarise clinicians with common phenotypes of patients with GA, the clinical and imaging features that may lead to rapid progression of GA in various phenotypes are highlighted. With the recent US Food and Drug Administration approval of new GA treatments that reduce lesion growth, understanding …

Development And Validation Of A Novel Clinical Risk Score To Predict Hypoxaemia In Children With Pneumonia Using The Who Prepare Dataset, Rainer Tan, Arjun Chandna, Tim Colbourn, Shubhada Hooli, Carina King, Norman Lufesi, Eric D Mccollum, Charles Mwansambo, Joseph L Mathew, Clare L Cutland, Shabir A Madhi, Marta Nunes, Sudha Basnet, Tor A Strand, Kerry-Ann F O'Grady, Brad Gessner, Emmanuel Addo-Yobo, Noel Chisaka, Patricia Hibberd, Prakash M Jeena, Juan M Lozano, William B Maleod, Archana Patel, Donald M Thea, Ngoc Tuong Vy Nguyen, Marilla Lucero, Syed Mohammad Akram Uz Zaman, Shinjini Bhatnagar, Nitya Wadhwa, Rakesh Lodha, Satinder Aneja, Mathuram Santosham, Shally Awasthi, Ashish Bavdekar, Monidarin Chou, Pagbajabyn Nymadawa, Jean William Pape, Glaucia Paranhos-Baccala, Valentina S Picot, Mala Rakoto-Andrianarivelo, Vanessa Rouzier, Graciela Russomando, Mariam Sylla, Philippe Vanhems, Jianwei Wang, Romina Libster, Alexey W Clara, Fenella Beynon, Gillian Levine, Chris A Rees, Mark I Neuman, Shamim Qazi, Yasir Bin Nisar, World Health Organization Prepare Study Group

Faculty, Staff and Students Publications

Background: Hypoxaemia predicts mortality at all levels of care, and appropriate management can reduce preventable deaths. However, pulse oximetry and oxygen therapy remain inaccessible in many primary care health facilities. We aimed to develop and validate a simple risk score comprising commonly evaluated clinical features to predict hypoxaemia in 2-59-month-old children with pneumonia.

Methods: Data from seven studies conducted in five countries from the Pneumonia Research Partnership to Assess WHO Recommendations (PREPARE) dataset were included. Readily available clinical features and demographic variables were used to develop a multivariable logistic regression model to predict hypoxemia (oxygen saturation < 90%) at presentation to care. The adjusted log coefficients were transformed to derive the PREPARE hypoxemia risk score and its diagnostic value was assessed in a held-out, temporal validation dataset. The model and risk score were analysed by evaluating the area under the receiver operating characteristic curve (AUC), sensitivity and specificity.

Results: We included 14 …

The Impact Of Agricultural Land Conversion On The Economy And Space Utilization In Jatimulyo And Way Huwi Villages, South Lampung Regency, Lampung Province, Yudha Rahman, Adnin Musadri Asbi, Annisa Maharani, Khalid Ahmad Ramadhan

Jurnal Geografi Lingkungan Tropik (Journal of Geography of Tropical Environments)

No abstract provided.

The Timing And Significance Of Mid-Crustal Shearing And Exhumation Of Amphibolite-Facies Rocks Along The Great Glen Fault Zone, Scotland, Richard D. Law, J. Ryan Thigpen, Calvin A. Mako, Andrew Kylander-Clark, Mark J. Caddick, Lowell R. Moore, Cassandra Becker, Robert E. Holdsworth, Robin A. Strachan, A. Graham Leslie

Earth and Environmental Sciences Faculty Publications

The Rosemarkie Inlier lies on the NW side of the Great Glen Fault Zone (GGFZ) and is composed of foliated and lineated Archean orthogneisses and Moine metasedimentary rocks. The mylonitic foliation strikes NE–SW (parallel to the GGFZ), dips steeply SE and contains a gently to moderately plunging mineral lineation. Microstructural and quartz c-axis fabric analyses indicate that oblique sinistral shearing occurred under amphibolite-facies conditions. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) analyses on monazite rims in the gneisses yielded ²⁰⁶Pb/²³⁸U ages of 401.8 ± 4.8 Ma (including 2 (Formula presented.) uncertainty and a propagated additional 1% …

Domain-Adaptive Diagnosis Of Lewy Body Disease With Transferability Aware Transformer, Xiaowei Yu, Jing Zhang, Tong Chen, Yan Zhuang, Minheng Chen, Chao Cao, Yanjun Lyu, Lu Zhang, Li Su, Tianming Liu, Dajiang Zhu

Computer Science Faculty Research & Creative Works

Lewy Body Disease (LBD) is a common yet understudied form of dementia that imposes a significant burden on public health. It shares clinical similarities with Alzheimer’s disease (AD), as both progress through stages of normal cognition, mild cognitive impairment, and dementia. A major obstacle in LBD diagnosis is data scarcity, which limits the effectiveness of deep learning. In contrast, AD datasets are more abundant, offering potential for knowledge transfer. However, LBD and AD data are typically collected from different sites using different machines and protocols, resulting in a distinct domain shift. To effectively leverage AD data while mitigating domain shift, …

Introduction To Sociology: Race And Ethnicity, Dr. Marcia Morrison Ph.D.

Open Educational Resources

Abstract: This paper critically examines the phrase "one nation, indivisible" from the Pledge of Allegiance in light of the complex realities of race, ethnicity, and immigration in the United States. While the pledge asserts a unified national identity, this ideal is frequently undermined by systemic social, economic, and political divisions. Drawing from multicultural and sociopolitical frameworks, the paper explores how the lived experiences of marginalized groups—particularly racial and ethnic minorities and immigrant communities—reveal a fragmented national reality. The analysis engages with the implications of the 1965 Immigration Act, which, despite dismantling explicitly racist immigration quotas, restructured racial inequalities through new …

Enhancing Diagnostic Reliability Through Centrifuge Validation And Staff Education: Quality Management Initiative In A Clinical Laboratory, Chris Agoki

MSMLS Capstone Projects

Abstract

This capstone project aims to enhance diagnostic reliability in a clinical laboratory by validating centrifuge performance and implementing an adult education-based training program within a quality management framework. Twenty archived, de-identified whole blood samples were analyzed to compare the performance of a new centrifuge with an existing model, focusing on plasma volume, hemolysis index, and Tacrolimus concentration.

The study demonstrated statistical and clinical equivalence between the devices, supporting the implementation of the new centrifuge. A staff training program, grounded in andragogical principles and guided by transformational leadership and Kotter’s 8-Step Change Model, was developed to integrate validation practices into …

Energetic And Economic Aspects Of Rebound, Part I: Foundations Of A Rigorous Analytical Framework, Matthew Kuperus Heun, Gregor Semieniuk, Paul E. Brockway

University Faculty Publications and Creative Works

Widespread implementation of energy efficiency is a key greenhouse gas emissions mitigation measure, but rebound can “take back” energy savings. However, the absence of solid analytical foundations hinders empirical determination of the size of rebound. A new clarity is needed, one that involves both economics and energy analysis. In this paper (Part I), we advance foundations of a rigorous analytical framework for consumer-sided rebound that starts at the microeconomic level and is approachable for both energy analysts and economists. We develop foundations of a framework that (i) clarifies the energy, expenditure, and consumption aspects of rebound, (ii) combines embodied energy …

Exploring The Validity Of Vocabulary Assessments In Racially, Dialectically, And Socioeconomically Diverse Preschool Populations, Lauren Betzer

LSU Master's Theses

Recent research has advocated for interactive assessments of vocabulary over more traditional, static assessments, as interactive assessments are more sensitive to linguistic and cultural diversity. Static vocabulary assessments, such as the Peabody Picture Vocabulary Test (PPVT), probe existing knowledge, while interactive assessments, such as the Quick Interactive Language Screener (QUILS), examines a child’s language in a wholistic manner by assessing previously learned vocabulary knowledge, syntactic knowledge, and processing when learning a new concept. It remains unclear which assessment more accurately captures children's vocabulary knowledge throughout the Deep South—a region characterized by its unique cultural and linguistic environment, which includes the …

Nurse Leader Onboarding, Jennifer Dawn Mcinerney

Walden Dissertations and Doctoral Studies

he objective of this Doctor of Nursing Practice project was to investigate the impact of a structured 30-60-90-day onboarding program, incorporating a competency-based checklist aligned with the American Organization for Nursing Leadership (AONL) nurse leader competencies, on nurse leader satisfaction. Nurse leaders, often promoted for their clinical skills, frequently lack the necessary support and training for their new roles, leading to high turnover rates. This project aimed to address this gap by developing and implementing a nurse leader education module, which was introduced to 23 nurse leaders over four sessions. A pre-/posttest survey was used to measure changes in satisfaction …

Evolving Trends: A Bibliometric Analysis Of Academic Librarians’ Publications At Twelve Aau Member Universities, Pete E. Pascuzzi, Jason B. Reed, Greenley Goedde Creech

Libraries Faculty and Staff Scholarship and Research

The goal of this bibliometric study was to explore the broader publication patterns of academic librarians in both information and library science (ISLS) and interdisciplinary research for the years 2009 - 2023. Web of Science data were collected for twelve academic libraries. The results showed that while the number of ISLS publications has dropped, interdisciplinary publications have increased dramatically with a broad range of disciplines represented, and collaborations in the medical sciences were a major contributor to this increase. The study suggests that some academic libraries have shifted their priorities over the past fifteen years and that the assessment of …

Self-Determination In The Implementation Of Treaty Reserved Rights, Kekek Jason Stark

Tribal Law Journal

No abstract provided.

Fulfilling An Obligated Duty To The Diné By Incorporating And Defining A Core Principle, Tó’Eí’Iiná Até (Water Is Life) Into The Navajo Nation Tribal Water Code: Making A Connection To The Diné In The “Checkerboard” Area., M. Tyanne Benallie

Tribal Law Journal

No abstract provided.

Stop Killing The Klamath: Rights Of Nature Protections With Tribal Law, The National Historic Preservation Act, And Collaborative Management Strategies For A Tribe On The Front Lines Of Climate Change, Juliette A. Jackson

Tribal Law Journal

No abstract provided.

Front Matter, Tribal Law Journal

Tribal Law Journal

No abstract provided.

From The Silver Screen To The Phone Screen: The Coogan Act’S Struggle To Keep Pace With The Evolution Of Social Media, Anzario Bernard Serrant

Minnesota Journal of Law, Science & Technology

No abstract provided.

Why The Ai Act Fails To Understand Generative Ai, Claire Boine, David Rolnick

Minnesota Journal of Law, Science & Technology

No abstract provided.

Surpassing Bostock: Sec Filing Deficits Mask Prevalence Of Lgbtq+ Workplace Discrimination In Big Tech, Clovia Hamilton, Eric Sader, Benjamin Ale-Ebrahim

Minnesota Journal of Law, Science & Technology

No abstract provided.

Lower Your Expectation Damages: Bipa Reforms Amplify Need For Federal Standards In Biometric Data Privacy, Jessica Schmitz

Minnesota Journal of Law, Science & Technology

No abstract provided.

The Green Energy Landfill: Regulatory Approaches To The Disposal Of Decommissioned Wind Turbine Blades, Samuel Taylor

Minnesota Journal of Law, Science & Technology

No abstract provided.

From Imaging To Computational Domains For Physics-Driven Molecular Biology Simulations: Hindered Diffusion In Platelet Masses, Catherine House, Ziyi Huang, Kaushik Shankar, Sandra Young, Meghan Roberts, Scott Diamond, Maurizio Tomaiuolo, Timothy Stalker, Lu Lu, Talid Sinno

Cardeza Foundation for Hematologic Research

When formed in vivo, murine hemostatic thrombi exhibit a heterogeneous architecture comprised of distinct regions of densely and sparsely packed platelets. In this study, we utilize high-resolution electron microscopy alongside machine learning and physics-based simulations to investigate how such clot microstructure impacts molecular diffusivity. We used Serial Block Face - Scanning Electron Microscopy (SBF-SEM) to image select volumes of hemostatic masses formed in a mouse jugular vein, producing high-resolution 2D images. Images were segmented using machine learning software (Cellpose), whose training was augmented by manually segmented images. The segmented images were then utilized as 2D computational domains for Lattice Kinetic …

Every Step You Take: Securing Employees' Location Data Privacy, Elizabeth A. Brown, Matthew M. Cummings

Minnesota Journal of Law, Science & Technology

No abstract provided.