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Articles 75841 - 75870 of 1739485
Full-Text Articles in Entire DC Network
Smokejumper Biographies For 1964 Rookie Class, National Smokejumper Association
Smokejumper Biographies For 1964 Rookie Class, National Smokejumper Association
Smokejumper Biographies by Rookie Year
This document contains short biographies of smokejumpers who rookied in 1964.
Smokejumper Biographies For 1962 Rookie Class, National Smokejumper Association
Smokejumper Biographies For 1962 Rookie Class, National Smokejumper Association
Smokejumper Biographies by Rookie Year
This document contains short biographies of smokejumpers who rookied in 1962.
Is R&D Rivalry Slowing The Growth Of Productive Firms?, Yoshiki Ando, James Bessen, Xiupeng Wang
Is R&D Rivalry Slowing The Growth Of Productive Firms?, Yoshiki Ando, James Bessen, Xiupeng Wang
Faculty Scholarship
The reallocation of jobs to more productive firms is a substantial component of aggregate productivity growth, yet job reallocation rates have declined substantially in the United States. This paper explores the hypothesis that greater technological rivalry has exacerbated adjustment costs, slowing reallocation. Using microdata at the US Census and estimates of technological rivalry in firm growth regressions, we find that technological rivalry slows firm responses to productivity shocks. Firms do not expand as rapidly in the face of higher obsolescence risk. Estimating counterfactual firm growth from 1997-2018, we find that growing technological rivalry accounts for most of the decline in …
Addressing Anxiety And Depression In The Allergy Clinic Through Motivational Interviewing, Brief Cognitive Behavioral Therapy, And Curious Questions, Jonathan A Bernstein, Don Bukstein, Aikaterini Anagnostou, Matthew Greenhawt, S Shahzad Mustafa, Julie Wang, Anna Nowak-Wegrzyn, Elissa M Abrams, John Oppenheimer, Alexandra E Conway, Andrew A White, Taylor A Doherty, Richard P Morse, Marcus Shaker
Addressing Anxiety And Depression In The Allergy Clinic Through Motivational Interviewing, Brief Cognitive Behavioral Therapy, And Curious Questions, Jonathan A Bernstein, Don Bukstein, Aikaterini Anagnostou, Matthew Greenhawt, S Shahzad Mustafa, Julie Wang, Anna Nowak-Wegrzyn, Elissa M Abrams, John Oppenheimer, Alexandra E Conway, Andrew A White, Taylor A Doherty, Richard P Morse, Marcus Shaker
Faculty, Staff and Students Publications
Allergic diseases, particularly food allergy, can be associated with significant psychosocial impairment. Allergist-immunologists can provide evidence-based information to correct misperceptions and misunderstandings regarding food allergy that may perpetuate cycles of fear and anxiety. Whereas motivational interviewing can be an empathetic approach to empower patients to actualize health goals, cognitive behavioral therapy (CBT) aims to provide disease-state insight to facilitate an understanding of risk that can transform health beliefs and behaviors. Brief CBT is a clinical approach that can help address ineffective management paradigms through conversations that begin with curious questions. In this review, we discuss evidence supporting implementation of an …
Anaphylaxis Definition, Overview, And Clinical Support Tool: 2024 Consensus Report-A Ga2len Project, Paul J Turner, Julie Wang, Graham Roberts, Aikaterini Anagnostou, Susanne Halken, Jay Liebermann, Margitta Worm, Torsten Zuberbier, Hugh A Sampson, Ga(2)Len Anaphylaxis Study Team
Anaphylaxis Definition, Overview, And Clinical Support Tool: 2024 Consensus Report-A Ga2len Project, Paul J Turner, Julie Wang, Graham Roberts, Aikaterini Anagnostou, Susanne Halken, Jay Liebermann, Margitta Worm, Torsten Zuberbier, Hugh A Sampson, Ga(2)Len Anaphylaxis Study Team
Faculty, Staff and Students Publications
Background: The 2006 National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network anaphylaxis criteria are widely used in clinical care and research. In 2020, the World Allergy Organization published modified criteria that have not been uniformly adopted. Different criteria contribute to inconsistent care and research outcomes.
Objective: We sought to develop a consensus anaphylaxis definition, overview, and clinical support tool.
Methods: A 12-member writing group developed draft outputs modified with input from a 46-member international expert panel, 31 medical stakeholder organizations, and 15 patient advocacy organizations. The expert panel participated in a modified Delphi process to seek consensus …
Mood And Sleep In Young Adults With Type 1 Diabetes, Sarah K Lyons, Randi Streisand, Barbara J Anderson, Siripoom V Mckay, Tricia S Tang, Sara Nowakowski, Ashley M Butler, Sridevi Devaraj, Marisa E Hilliard
Mood And Sleep In Young Adults With Type 1 Diabetes, Sarah K Lyons, Randi Streisand, Barbara J Anderson, Siripoom V Mckay, Tricia S Tang, Sara Nowakowski, Ashley M Butler, Sridevi Devaraj, Marisa E Hilliard
Faculty, Staff and Students Publications
Objective: Depression is associated with sleep problems, and both are associated with higher HbA1c in people with type 1 diabetes (T1D). However, little is known about depressed mood and sleep in young adults with T1D. The aims of this secondary analysis were to provide descriptive statistics of multiple aspects of mood and sleep in young adults with T1D and evaluate associations of depressed mood, diabetes distress, and sleep quality and duration.
Methods: At baseline of a behavioral intervention trial, young adults with T1D completed self-report measures of sleep, diabetes distress, and depressive symptoms. We described sleep metrics across racial/ethnic groups …
Privacy In Perspective: Research Participants’ Priorities And Concerns Related To Sharing Data Generated In Human Neuroscience Studies, Mary A Majumder, Kathryn Maxson Jones, Whitney Bash Brooks, Sameer A Sheth, Amy L Mcguire
Privacy In Perspective: Research Participants’ Priorities And Concerns Related To Sharing Data Generated In Human Neuroscience Studies, Mary A Majumder, Kathryn Maxson Jones, Whitney Bash Brooks, Sameer A Sheth, Amy L Mcguire
Faculty, Staff and Students Publications
The societal benefits from sharing and reusing data collected in human neuroscience studies are widely appreciated. However, there are persistent barriers to data sharing as well as privacy concerns related to unauthorized access, misuse, and reidentification of deidentified data. Thus far, few studies have been conducted with neuroscience research participants to understand their data sharing priorities and concerns. We conducted a survey utilizing an experimental design with N=52 participants in neuroscience studies funded by the U.S. National Institutes of Health representing diverse neurotechnologies and health conditions. Respondents prioritized sharing practices that maximize reuse of data to benefit patients and reduce …
Gastrointestinal Infection Before Immune Checkpoint Inhibition Hinders Treatment Efficacy And Increases The Risk Of Colitis, Kei Takigawa, Irene Jeong-Ah Lee, Andrew Sullivan, Tanvi Gupta, Linfeng Lu, Raakhi Menon, Ayesha Khan, Hamza Salim, Elliot Baerman, Carolina Colli Cruz, Cristina Natha, Varun Vemulapalli, Garrett Coleman, Krishnavathana Varatharajalu, Christopher Fan, Pablo Okhuysen, Anthony J Olszanski, Yan Zhou, Hao Chi Zhang, Mehnaz Shafi, Yinghong Wang
Gastrointestinal Infection Before Immune Checkpoint Inhibition Hinders Treatment Efficacy And Increases The Risk Of Colitis, Kei Takigawa, Irene Jeong-Ah Lee, Andrew Sullivan, Tanvi Gupta, Linfeng Lu, Raakhi Menon, Ayesha Khan, Hamza Salim, Elliot Baerman, Carolina Colli Cruz, Cristina Natha, Varun Vemulapalli, Garrett Coleman, Krishnavathana Varatharajalu, Christopher Fan, Pablo Okhuysen, Anthony J Olszanski, Yan Zhou, Hao Chi Zhang, Mehnaz Shafi, Yinghong Wang
Faculty, Staff and Students Publications
Background: Gastrointestinal (GI) infections, which often result in or stem from intestinal dysbiosis, can affect the efficacy of immune checkpoint inhibitors (ICIs) and increase the risk of adverse effects, such as colitis. In this study, we explored the impact of GI infections before initiation of ICI therapy on the incidence and severity of immune-mediated colitis (IMC) and survival.
Methods: A single-center, retrospective review including all patients who received ICIs from January 2010 to February 2024 and subsequently developed IMC. Patients were screened for IMC and prior GI infections based on symptoms and stool tests. Patients' demographic, IMC, and GI infection-related …
Evaluation Of A Region-Wide Hospital-Based Violence Intervention Program : A Pilot Cohort Study, Daphne Lew, Vicki Moran, Rachel M Ancona, Kateri Chapman-Kramer, Melik Coffey, Keyria Page, Abigail Batha, Stephanie Harris, Larita Rice-Barnes, Marsha Williams, Lindsay M Kranker, Marguerite W Spruce, Christopher Behr, Michael A Mancini, Douglas J E Schuerer, Lindsay D Clukies, Nicole Santucci, Anne Trolard, Victoria Anwuri, Megan L Ranney, Randi E Foraker, Matt Vogel
Evaluation Of A Region-Wide Hospital-Based Violence Intervention Program : A Pilot Cohort Study, Daphne Lew, Vicki Moran, Rachel M Ancona, Kateri Chapman-Kramer, Melik Coffey, Keyria Page, Abigail Batha, Stephanie Harris, Larita Rice-Barnes, Marsha Williams, Lindsay M Kranker, Marguerite W Spruce, Christopher Behr, Michael A Mancini, Douglas J E Schuerer, Lindsay D Clukies, Nicole Santucci, Anne Trolard, Victoria Anwuri, Megan L Ranney, Randi E Foraker, Matt Vogel
Faculty, Staff and Students Publications
Background: Violent injury survivors are at risk for revictimization. The St. Louis area hospital-based violence intervention program (HVIP), Life Outside of Violence (LOV), is the first multisystem, region-wide HVIP in the United States.
Objective: To describe the LOV program during its pilot phase and evaluate violent reinjury 1 year after index injury among LOV participants.
Design: Pilot observational cohort study of violently injured patients.
Setting: Data were queried from the program's multisystem data repository, which contains individual encounter-level data for all violent injury visits from the 2 adult and 2 pediatric LOV-partner level 1 trauma hospitals.
Participants: Patients eligible for …
Deterioration And Manifestation Of Cerebral Fat Embolism Triggered By Bone Reaming During Femur Fracture Surgery: A Case Report, Yohei Fujimoto, Masahiro Miyashita, Tadashi Matsuura, Takashi Mori
Deterioration And Manifestation Of Cerebral Fat Embolism Triggered By Bone Reaming During Femur Fracture Surgery: A Case Report, Yohei Fujimoto, Masahiro Miyashita, Tadashi Matsuura, Takashi Mori
Faculty, Staff and Students Publications
The role of intramedullary reaming in triggering fat embolism syndrome (FES) remains debated. This case, where FES developed during reaming, provides further evidence supporting reaming as a potential risk factor for FES.
Relapse Patterns Among Children And Adolescents With Kaposi Sarcoma In Malawi, William Kamiyango, Jimmy Villiera, Parth S Mehta, Erin Peckham-Gregory, Mark Zobeck, Michael E Scheurer, Carl E Allen, Rizine Mzikamanda, Nmazuo W Ozuah, Nader Kim El-Mallawany
Relapse Patterns Among Children And Adolescents With Kaposi Sarcoma In Malawi, William Kamiyango, Jimmy Villiera, Parth S Mehta, Erin Peckham-Gregory, Mark Zobeck, Michael E Scheurer, Carl E Allen, Rizine Mzikamanda, Nmazuo W Ozuah, Nader Kim El-Mallawany
Faculty, Staff and Students Publications
Kaposi Sarcoma (KS) is a common childhood cancer in Malawi, but few studies have exploredclinical characteristicsofrelapsed disease. We aimed to characterize clinical patterns of relapse to improve treatment and, ultimately, long-term survival in patients with pediatric KS.A retrospective cohort study was conducted among patients ages < 19 years of age at time of KS diagnosis in Lilongwe, Malawi between August 1, 2010 and March 15, 2020. Specifically, emphasis was placed on patients who had relapsed disease and excluded patients with refractory disease or those who died whilst receiving front-line treatment. Salvage therapy typically involved an intensified chemotherapy regimen compared to front-line therapy—namely nonliposomaldoxorubicin plus bleomycin/vincristine or paclitaxel monotherapy.One-hundred and ninety patients with pediatric KS were included in this analysis, 50 of whom experienced relapse (26%).Older median age was associated with occurrence of relapse (10 vs 6.7 years, p-value = 0.004). Median time from diagnosis to first relapse was 10.6 months (range 2.3–49 months). Three-year post-relapse overall survival (OS) for the entire cohort was 60% with a median follow-up time of 4.7 years after relapse.Survival was significantly higher for patients who relapsed with the woody edema clinical phenotype of pediatric KS versus those with visceral/disseminated disease—3-year OS 79% (95% CI 62–100) versus 29% (14–61).These data demonstrate potential for continued survival after KS relapse in the pediatric population and identify subsets of high-risk patients. The higher mortality observed in patients with visceral/disseminated KS highlights the need for improved therapeutic strategies.
Effective Algorithm To Differentiate Nbs Mcadd Cases From Carriers And Non-Carriers And An Assessment Of The Utility Of The Second Newborn Screen For Mcadd, Qin Sun, Yue Wang, Xi Luo, Yishay Ben-Moshe, Lindsay C Burrage, V Reid Sutton
Effective Algorithm To Differentiate Nbs Mcadd Cases From Carriers And Non-Carriers And An Assessment Of The Utility Of The Second Newborn Screen For Mcadd, Qin Sun, Yue Wang, Xi Luo, Yishay Ben-Moshe, Lindsay C Burrage, V Reid Sutton
Faculty, Staff and Students Publications
False positives are an inherent part of newborn screening that can increase both costs to the healthcare system and parental anxiety. Previous studies primarily examined presumptive positive rates for medium-chain acyl-CoA dehydrogenase deficiency (MCADD) in places conducting one newborn screen (NBS), with predominantly white, non-Hispanic subjects. Texas performs two NBSs and there is a majority Hispanic population in our region. This study aims to analyze biochemical and DNA data to more easily distinguish affected individuals from carriers or healthy non-carriers and identify benefits and challenges of a second NBS for MCADD. Biochemical and targeted DNA data from NBS dried blood …
Genetic Diversity And Expanded Phenotypes In Dystonia: Insights From Large-Scale Exome Sequencing, Gamze Kilic-Berkmen, Ai Huey Tan, Shen-Yang Lim, Ebba Lohmann, Kaja M Schröder, Lea Ipsen, Lena A Nothacker, Linn Welzel, Alexandra S Rudnik, Frauke Hinrichs, Thorsten Odorfer, Kirsten E Zeuner, Friederike Schumann, Andrea A Kühn, Simone Zittel, Marius Moeller, Robert Pfister, Christoph Kamm, Anthony E Lang, Yi Wen Tay, Ana Luísa De Almeida Marcelino, Marie Vidailhet, Emmanuel Roze, Joel S Perlmutter, Jeanne S Feuerstein, Victor S C Fung, Florence Chang, Richard L Barbano, Steven Bellows, Aparna A Wagle Shukla, Alberto J Espay, Mark S Ledoux, Brian D Berman, Stephen Reich, Andres Deik, Andre Franke, Michael Wittig, Sören Franzenburg, Jens Volkmann, Norbert Brüggemann, H A Jinnah, Tobias Bäumer, Christine Klein, Hauke Busch, Katja Lohmann
Genetic Diversity And Expanded Phenotypes In Dystonia: Insights From Large-Scale Exome Sequencing, Gamze Kilic-Berkmen, Ai Huey Tan, Shen-Yang Lim, Ebba Lohmann, Kaja M Schröder, Lea Ipsen, Lena A Nothacker, Linn Welzel, Alexandra S Rudnik, Frauke Hinrichs, Thorsten Odorfer, Kirsten E Zeuner, Friederike Schumann, Andrea A Kühn, Simone Zittel, Marius Moeller, Robert Pfister, Christoph Kamm, Anthony E Lang, Yi Wen Tay, Ana Luísa De Almeida Marcelino, Marie Vidailhet, Emmanuel Roze, Joel S Perlmutter, Jeanne S Feuerstein, Victor S C Fung, Florence Chang, Richard L Barbano, Steven Bellows, Aparna A Wagle Shukla, Alberto J Espay, Mark S Ledoux, Brian D Berman, Stephen Reich, Andres Deik, Andre Franke, Michael Wittig, Sören Franzenburg, Jens Volkmann, Norbert Brüggemann, H A Jinnah, Tobias Bäumer, Christine Klein, Hauke Busch, Katja Lohmann
Faculty, Staff and Students Publications
Objective: Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly complex.
Methods: Exome sequencing was conducted on 1924 genetically unsolved, mainly late-onset isolated dystonia patients, recruited primarily from two dystonia registries (DysTract and the Dystonia Coalition). Rare variants in genes previously linked to dystonia (n = 406) were examined, confirmed via Sanger sequencing, and analyzed for segregation when possible.
Results: We identified 137 distinct likely pathogenic/pathogenic variants (according to ACMG …
Ambient Documentation Technology In Clinician Experience Of Documentation Burden And Burnout, David Y Ting, Sayon Dutta, Julie C Wang, Amanda J Centi, Molly Macfarlane, Eran Bechor, Jonathan Letourneau, Gabrielle Choo-Kang, Esther H Kim, Cordula Magee, Brian J Lang, Laura Angelo, Jackson Olin, Michelle Frits, Christine Iannaccone, Angela Rui, Ivana Salmikova, Christopher Holland, Bryan Blanchette, Rachel Silverman, David W Bates, Lisa Rotenstein, Rebecca G Mishuris
Ambient Documentation Technology In Clinician Experience Of Documentation Burden And Burnout, David Y Ting, Sayon Dutta, Julie C Wang, Amanda J Centi, Molly Macfarlane, Eran Bechor, Jonathan Letourneau, Gabrielle Choo-Kang, Esther H Kim, Cordula Magee, Brian J Lang, Laura Angelo, Jackson Olin, Michelle Frits, Christine Iannaccone, Angela Rui, Ivana Salmikova, Christopher Holland, Bryan Blanchette, Rachel Silverman, David W Bates, Lisa Rotenstein, Rebecca G Mishuris
Faculty, Staff and Students Publications
Importance: Documentation burden is associated with clinician burnout. To address documentation burden, Mass General Brigham (MGB) in Somerville, Massachusetts, and Emory Healthcare in Atlanta, Georgia, have piloted ambient documentation technology (ADT), which develops artificial intelligence-drafted clinical notes from clinician-patient conversations.
Objective: To examine the prevalence of ADT use and its association with clinicians' experience of documentation burden and burnout before and after use.
Design, setting, and participants: This survey study included clinicians who used ADT for at least 42 days and responded to both the pre- and postsurveys (onboarded February 27 to July 31, 2024, at MGB and July 19, …
The Splicing Factor Kinase Srpk1 Is A Therapeutic Target For Peripheral Vascular Disease, Amira Zawia, Federica Riu, Yizhuo Gao, Jyoti Agrawal, Amy P Lynch, Maria J C Machado, Tom Hawtrey, Ryosuke Kikuchi, Kathryn R Green, Lydia Teboul, Claire Allen, Zoe Blackley, Keerthana Rajaji, Jennifer Batson, Steven J Harper, Sebastian Oltean, Winfried Amoaku, Andrew V Benest, Jonathan C Morris, Bruce Braithwaite, David O Bates
The Splicing Factor Kinase Srpk1 Is A Therapeutic Target For Peripheral Vascular Disease, Amira Zawia, Federica Riu, Yizhuo Gao, Jyoti Agrawal, Amy P Lynch, Maria J C Machado, Tom Hawtrey, Ryosuke Kikuchi, Kathryn R Green, Lydia Teboul, Claire Allen, Zoe Blackley, Keerthana Rajaji, Jennifer Batson, Steven J Harper, Sebastian Oltean, Winfried Amoaku, Andrew V Benest, Jonathan C Morris, Bruce Braithwaite, David O Bates
Faculty, Staff and Students Publications
In peripheral arterial disease (PAD), antiangiogenic VEGF-A165b isoform overexpression in monocytes contributes to impaired collateralization. Serine-arginine protein-kinase-1 (SRPK1) regulates VEGF splicing. To determine whether SRPK1 controlled monocytic VEGF, impairing collateralization, we investigated SRPK1 inhibition and monocyte-specific knockout in mouse models of and in human monocytes from PAD. VEGF-A165b activity was measured by coculture of monocytes from patients with PAD with endothelial cells with SRPK1 inhibition. Mice with impaired revascularization due to soluble-frizzled-related-protein-5 knockout (Sfrp5-/-), monocyte-specific Wnt5a gain-of-function (LysM-Wnt5aGOF), or obese mice on a high-fat high-sucrose (HF/HS) diet were subjected to femoral artery ligation and treated with …
Glycerol Kinase Gene Variant As A Cause Of Pseudohypertriglyceridemia And Apparent Poor Response To Plozasiran, Diane Brisson, Bruce Given, Daniel Gaudet
Glycerol Kinase Gene Variant As A Cause Of Pseudohypertriglyceridemia And Apparent Poor Response To Plozasiran, Diane Brisson, Bruce Given, Daniel Gaudet
Faculty, Staff and Students Publications
Severe hypertriglyceridemia (HTG) is characterized by plasma triglyceride (TG) levels >500 mg/dL (SI: 5.7 mmol/L) (reference range, < 150 mg/dL [SI: < 1.7 mmol/L]) and is linked to cardiovascular disease and pancreatitis risk. Treatment typically involves dietary restrictions and lipid-lowering medications. Glycerol kinase deficiency (GKD) is a rare genetic disorder that causes pseudo-HTG.
In SHASTA-2, a study of patients with severe HTG, most subjects (>90%) treated with plozasiran, an apolipoprotein C-III (APOC3) small interfering RNA (siRNA), achieved TG levels < 500 mg/dL (SI: 5.7 mmol/L), below the risk threshold for acute pancreatitis. We report herein a case study of a 65-year-old male apparently not responding to plozasiran. The patient was shown to carry a loss-of-function variant in the GK gene resulting in GKD, with high free glycerol (40.24 mg/dL or 4.37 mmol/L) (reference range, 0.03-0.13 mmol/L) that contributed to an overestimation of TG concentration. After correcting for free glycerol, the patient was noted to have had mild HTG, with plozasiran treatment decreasing real TG values by up to 71%.
This case report suggests that …
Hospital Experiences And Medical Traumatic Stress In Adults With Spina Bifida, Monique Ridosh
Hospital Experiences And Medical Traumatic Stress In Adults With Spina Bifida, Monique Ridosh
Faculty, Staff and Students Publications
Purpose
This study examined hospital and emergency department (ED) experiences of adults with spina bifida (SB), medical traumatic stress (MTS) and participant characteristics including anxiety, depression, post-traumatic stress disorder (PTSD) symptoms, and resiliency scores.
Methods
Adults with SB who had a hospital or ED encounter within the last five years were recruited from a medical home clinic and completed a structured interview and validated questionnaires. Narrative inquiry was used and descriptive analyses were conducted. MTS scores were reported per participant characteristics and emotional health questionnaire score counts and percentages.
Results
Twenty-five adults with SB representing 37% of eligible patients were …
Characterization Of Visual Field Loss Over 4 Years In The Rate Of Progression In Ush2a-Related Retinal Degeneration (Rush2a) Study, Nicole R Doucet, Isabelle Audo, Allison R Ayala, Janet K Cheetham, Peiyao Cheng, Todd A Durham, Rachel M Huckfeldt, Robert B Hufnagel, K Thiran Jayasundera, Naheed Khan, Brett Malbin, Ramiro S Maldonado, Michel Michaelides, Mark E Pennesi, Christina Y Weng, Alex Zmejkoski, Shobana Aravind, Hiroshi Ishikawa, David G Birch
Characterization Of Visual Field Loss Over 4 Years In The Rate Of Progression In Ush2a-Related Retinal Degeneration (Rush2a) Study, Nicole R Doucet, Isabelle Audo, Allison R Ayala, Janet K Cheetham, Peiyao Cheng, Todd A Durham, Rachel M Huckfeldt, Robert B Hufnagel, K Thiran Jayasundera, Naheed Khan, Brett Malbin, Ramiro S Maldonado, Michel Michaelides, Mark E Pennesi, Christina Y Weng, Alex Zmejkoski, Shobana Aravind, Hiroshi Ishikawa, David G Birch
Faculty, Staff and Students Publications
Purpose: To report visual field loss using static perimetry (SP) and kinetic perimetry (KP) over 4 years in the Rate of Progression of USH2A-related Retinal Degeneration (RUSH2A) study.
Design: Prospective, observational cohort study.
Subjects, participants, and/or controls: Participants had USH2A-related rod-cone degeneration, visual acuity ≥20/80, and KP III4e ≥10° at baseline in the study eye. Preserved cohorts with baseline visual fields sufficient to detect progression were identified.
Methods: Participants were examined annually through 4 years. Mixed-effects models were used to estimate the annual, standardized rate, and percentage rates of change.
Main outcome measures: SP measures included hill of vision (total: …
Novel Parent Survey Measures Sensory Behaviors Incorporating Sensory Modality And Stimulus Intensity, Joon Lee, Stephanie Marton, Jill Roth, Frederick L Oswald, Kenneth J Nobleza, Ankona Banerjee, Holly Harris, Ariel M Lyons-Warren
Novel Parent Survey Measures Sensory Behaviors Incorporating Sensory Modality And Stimulus Intensity, Joon Lee, Stephanie Marton, Jill Roth, Frederick L Oswald, Kenneth J Nobleza, Ankona Banerjee, Holly Harris, Ariel M Lyons-Warren
Faculty, Staff and Students Publications
Objective: Sensory behaviors are common, clinically relevant features of many neurodevelopmental disorders, including autism. However, existing assessments lack granularity in evaluating hypersensitivity and hyposensitivity, particularly in relation to stimulus intensity. We address this gap with our Sensory Response Questionnaire Phenotyper (SRQP), a parent-questionnaire that comprehensively assesses sensory behaviors across five sensory modalities. The purpose of this study was to validate the SRQP against established tools and assess its efficacy in identifying nuanced sensory processing patterns in children with autism.
Methods: A convenience sample of 317 participants (57 with autism, 260 typically developing) aged 3-17 years were enrolled in a cross-sectional …
What The ‘One Big Beautiful Bill’ Means For Dentists, John Looby Cpa, Theodore C. Schumann Ii Mba, Msf, Cfp, Aif
What The ‘One Big Beautiful Bill’ Means For Dentists, John Looby Cpa, Theodore C. Schumann Ii Mba, Msf, Cfp, Aif
The Journal of the Michigan Dental Association
Executive Summary: The One Big Beautiful Bill (OBBB), signed July 4, 2025, significantly impacts dentists by extending and making permanent many 2017 tax policies. Key tax changes include permanent tax rates, an increased state and local income tax (SALT) cap, and new deductions for seniors, qualified tips, overtime wages, charitable donations, and auto loan interest. The qualified business income deduction is now permanent, and first-year bonus depreciation is restored. New "Trump Accounts" are established for children. Crucially, the OBBB introduces $50,000 annual and $200,000 lifetime caps on professional degree student loans, effective July 2026, and establishes the Repayment Assistance Plan …
J Mich Dent Assoc August 2025
The Journal of the Michigan Dental Association
Each month, The Journal of the Michigan Dental Association provides news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. It stands as the primary publication reaching Michigan dentists. The August issue marks the end of digital only publishing, as the MDA announced it will provide members a bimonthly print issue along with monthly digital distribution. This issue includes:
- A cover feature on the impact on the dental community of the recently adopted Big Beautiful Bill federal budget
- Mandibular Lingual Concavity Evaluation Using CBCT
- A reprinted clinical feature from New York on …
Guest Editorial: Who’S Special Now?, Michael Maihofer Dds
Guest Editorial: Who’S Special Now?, Michael Maihofer Dds
The Journal of the Michigan Dental Association
This editorial discusses a controversial change in Michigan's dental specialty advertising law, which occurred in 2020. Previously, only state-recognized specialists, undergoing rigorous advanced training, could advertise their specialty status. However, a new rule, resulting from an out-of-court settlement, paradoxically allows general dentists not recognized as specialists to advertise as such without following advertising rules. This change is criticized for undermining public protection and creating unethical, misleading situations where general dentists advertise as pediatric dentists, for instance. The Michigan Dental Association (MDA) is actively working to revert this law by supporting House Bills 4593 and 4594 to ensure only recognized specialists …
Mandibular Lingual Concavity Evaluation Using Cone Beam Computed Tomography, Anthony L. Neely Dds, Mdentsc, Phd, Bassam M. Kinaia Dds, Ms, Dicoi, Lidya Jirjis Dds, Ms, Dalia Hasso Dds, Ms, Jonathan Zora Dds, Ms, David Van Winkle Dds, Naiomy Perez-Villanueva, Sharhdad Kazerani Dds, Ms, Samual Korkis Dds, Ms, Omar Masabni Dds, Ms, James R. Geist Dds, Ms
Mandibular Lingual Concavity Evaluation Using Cone Beam Computed Tomography, Anthony L. Neely Dds, Mdentsc, Phd, Bassam M. Kinaia Dds, Ms, Dicoi, Lidya Jirjis Dds, Ms, Dalia Hasso Dds, Ms, Jonathan Zora Dds, Ms, David Van Winkle Dds, Naiomy Perez-Villanueva, Sharhdad Kazerani Dds, Ms, Samual Korkis Dds, Ms, Omar Masabni Dds, Ms, James R. Geist Dds, Ms
The Journal of the Michigan Dental Association
Dental implant placement in the posterior mandible can be impacted by the presence of the lingual concavity. Perforating the lingual cortical bone could lead to life-threatening hemorrhage/airway obstruction. The aim of this retrospective study is to examine dentate and partially edentulous mandibles to describe anatomical variations related to the lingual concavity by evaluating cone beam computed tomography (CBCT).
Mda At Your Service: What’S The Mda Doing To Help The Hygienist Shortage?, Rachel Sinacola Dds
Mda At Your Service: What’S The Mda Doing To Help The Hygienist Shortage?, Rachel Sinacola Dds
The Journal of the Michigan Dental Association
This article details the MDA's efforts to address Michigan's dental hygienist shortage, which saw about 3,000 licensed RDHs leave the workforce since 2020. Initiatives include paid social media campaigns targeting potential and former RDHs, although enrollment impacts have been minimal. The MDA is also collaborating with hygiene schools, helping Ferris State University secure funding to double its size and working with North Central Michigan College to establish a new school. Discussions are underway to explore allowing internationally trained dentists to perform hygiene duties. Additionally, the MDA endorses MEDVA for virtual assistant staffing, promoting HIPAA-compliant human professionals who handle remote administrative …
The New Professional: Tracking Success: Essential Kpis For Owners And Associates, Amrita Patel Dds
The New Professional: Tracking Success: Essential Kpis For Owners And Associates, Amrita Patel Dds
The Journal of the Michigan Dental Association
This article underscores the importance of Key Performance Indicators (KPIs) for data-driven success in modern dental practices. For new practice owners, essential KPIs include production, collections, and overhead ratio to ensure financial stability and operational efficiency. Patient flow metrics, such as new patient numbers and retention rates, are vital for growth. For both owners and associates, case acceptance rate reflects treatment plan conversion, and chair time utilization measures clinical efficiency. Other critical KPIs encompass hygiene production, patient satisfaction scores, online reviews, and accounts receivable aging. Associates can also track personal production and referral patterns for career development.
Staff Matters: Adding Background Checks And Drug Testing To The Hiring Process, Jodi Schafer Sphr, Shrm-Scp
Staff Matters: Adding Background Checks And Drug Testing To The Hiring Process, Jodi Schafer Sphr, Shrm-Scp
The Journal of the Michigan Dental Association
This article advises dental practices on legally and carefully implementing pre-employment background checks and drug testing. It emphasizes ensuring non-discriminatory practices by consistently applying policies and clearly defining screening criteria. Practices must obtain written applicant authorization and provide notification of Fair Credit Reporting Act (FCRA) rights before conducting checks. When evaluating results, relevance to the job and timing of convictions should be considered, avoiding blanket bans. For drug testing, transparency is key. Given Michigan's recreational marijuana legality, a positive THC test does not automatically indicate impairment, requiring practices to define their approach. Using a reputable third-party provider for both screenings …
Mda Insurance: How Offering Great Benefits Makes Your Practice Attractive To Employees, Craig Start Mba
Mda Insurance: How Offering Great Benefits Makes Your Practice Attractive To Employees, Craig Start Mba
The Journal of the Michigan Dental Association
This article highlights the critical role of employee benefits in attracting and retaining staff in dental practices, particularly given the low unemployment rates for hygienists and assistants. Beyond competitive pay and flexible hours, a robust benefit package, including both employer-paid and voluntary options, is increasingly vital. The MDA Health Plan offers flexible group health insurance options for members. Voluntary benefits such as vision, life, disability, accident, critical illness, and hospital indemnity insurance are attractive, with Section 125 (cafeteria) plans allowing pre-tax premium payments and offering payroll tax reductions for employers. These benefits provide essential financial security and enhance overall compensation.
The Back Page: Hospital General Dentistry: Needed Now More Than Ever, Tanaya K. Porter Dds, Craig C. Spangler Dds
The Back Page: Hospital General Dentistry: Needed Now More Than Ever, Tanaya K. Porter Dds, Craig C. Spangler Dds
The Journal of the Michigan Dental Association
This commentary emphasizes the increasing necessity of hospital-based general dentists. Historically, dentists faced challenges for privileges in hospitals, but today they are crucial, especially for neurodivergent adult patients and those with complex chronic illnesses requiring general anesthesia for dental care. Untreated oral issues can lead to severe infections, complicating acute medical conditions and threatening the success of life-saving surgeries like organ transplants. Hospital dentists provide vital pre-surgical evaluation, diagnosis, and follow-up care to prevent dental complications and improve patient quality of life post-surgery. Despite their critical role, the article highlights a concerning trend of fewer hospitals having general dentists on …
Mda Services: Endorsed Programs News
Mda Services: Endorsed Programs News
The Journal of the Michigan Dental Association
Throughh MDA Services, the Michigan Dental Association (MDA) has announced several endorsed programs aimed at supporting dental practices across Michigan: Compass Dental Gas Service is now endorsed by the MDA for its expertise in installing, maintaining, and repairing dental gas systems. Members benefit from exclusive discounts and safety compliance support. MEDVA Virtual Staffing offers HIPAA-compliant, human virtual assistants to handle administrative tasks remotely. This service helps reduce labor costs and allows in-office staff to focus on patient care. MDA Health Plan sponsors are reminded to submit overdue eligibility verification documents, which are essential for compliance and 2026 renewal preparations. DBS …
Temporal Disparities In Diagnosis: The Critical Impact Of Laboratory Workflow Inefficiencies On Outcomes In Metabolic And Cardiovascular Disorders, Evans Dzreke, Celene Dzreke, Ramseyer Adekorang Asamoah, David Kanze
Temporal Disparities In Diagnosis: The Critical Impact Of Laboratory Workflow Inefficiencies On Outcomes In Metabolic And Cardiovascular Disorders, Evans Dzreke, Celene Dzreke, Ramseyer Adekorang Asamoah, David Kanze
Health & Biomedical Sciences Faculty Publications
Diagnostic delays and laboratory process inefficiencies constitute a common but unaddressed dilemma in contemporary healthcare, quietly undermining patient outcomes in metabolic and cardiovascular illnesses where immediate intervention is critical. This seminal work goes beyond traditional operational viewpoints to demonstrate diagnostic inefficiency as an independent, adjustable risk factor with far-reaching implications. We rigorously quantified the impact of delayed test processing and reporting on clinical outcomes using a comprehensive mixed-methods approach that included multi-center retrospective cohort analysis (N=128,743 patients), real-time workflow mapping across 37 laboratories, in-depth case reviews, and economic modeling. Our findings challenged conventional wisdom by indicating that each 24-hour increase …