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Cover And Contents Jul 2025

Cover And Contents

Turkish Journal of Botany

No abstract provided.


The Effects Of S-Metolachlor On Some Fatty Acids And Fatty Acids Gene Expressions In Safflower (Carthamus Tinctorius L.), Gi̇zem Nardemi̇r, Güleray Ağar, Mahmut Si̇nan Taşpinar Jul 2025

The Effects Of S-Metolachlor On Some Fatty Acids And Fatty Acids Gene Expressions In Safflower (Carthamus Tinctorius L.), Gi̇zem Nardemi̇r, Güleray Ağar, Mahmut Si̇nan Taşpinar

Turkish Journal of Botany

Safflower (Carthamus tinctorius (L.)) is one of the widely studied plants due to its resistance to abiotic stress, suitability for summer and winter cultivation, rich in nutrients and linoleic acid. Thus, it has become more important compared to other oil plants in recent years. Weed infestation affects the growth of this cultivated plant during the greening period. S-metolachlor is one of the widely used herbicides that prevent the growth of weeds. In this study, three different doses of S-metolachlor (1, 2 and 4 g of active substance/L) were applied to two different safflower genotypes (Dinçer and Remzibey-05), and their effects …


Union Employees’ Perceptions And Lived Experiences Of Organizational Culture And Job Satisfaction In Michigan Manufacturing Organizations, Angela Wantuck Jul 2025

Union Employees’ Perceptions And Lived Experiences Of Organizational Culture And Job Satisfaction In Michigan Manufacturing Organizations, Angela Wantuck

Walden Dissertations and Doctoral Studies

Manufacturing organizational cultures steeped in tradition, corporate loyalty, and paternalistic values have experienced a decrease in union employee engagement and organizational satisfaction. Manufacturing leaders are concerned with this decrease as a primary indicator of employee walkouts or union strikes, impeding the manufacturing process, and affecting market share, profitability, and local economies. The purpose of this qualitative hermeneutic phenomenology study was to explore the union employees’ perceptions and lived experiences of organizational culture and job satisfaction in Michigan manufacturing organizations. Shaped by Schein’s organizational culture theory, the research question queried the perceptions of the union-represented employees as a subculture in the …


Effect Of Sodium Dodecyl Sulfate And Three Commercial Detergents On The Growth And Physiological Parameters Of The Filamentous Green Alga Cladophora Sp., Eduardo Ruíz-Hernández, Alma Socorro Sobrino-Figueroa, César Abelardo González Ramírez, José Roberto Villagómez-Ibarra Jul 2025

Effect Of Sodium Dodecyl Sulfate And Three Commercial Detergents On The Growth And Physiological Parameters Of The Filamentous Green Alga Cladophora Sp., Eduardo Ruíz-Hernández, Alma Socorro Sobrino-Figueroa, César Abelardo González Ramírez, José Roberto Villagómez-Ibarra

Turkish Journal of Botany

Surfactants are pollutants of environmental concern. Released in large volumes into aquatic environments, they have detrimental effects on the growth and physiological functions of living organisms. This study aimed to determine physiological effects of sodium dodecyl sulfate (SDS) and three commercial detergents on filamentous alga Cladophora sp. It followed the methodological guidelines of the Organisation for Economic Cooperation and Development (OECD) to test seven concentrations of SDS (0, 0.1, 1, 5, 10, 50, and 100 mg/L) and six concentrations of commercial detergents (0, 1, 15, 30, 45, and 60 mg/L) using three replicates in a fully randomized design. At the …


Responding To Police Perjury, David R. Katner Jul 2025

Responding To Police Perjury, David R. Katner

Cleveland State Law Review

The way in which defense lawyers phrase their challenges in criminal proceedings where police witnesses are thought to have committed perjury might place decisionmakers in the awkward position of unintentionally or intentionally coming to the aid of the witnesses who are unable to defend themselves during closing arguments. This article proposes a shift in the paradigm of how defense counsel characterize and handle testimony that seems untruthful, without having to engage in tactics that intend to be disrespectful to all police officers, let alone to the witnesses in the trial. Creating a continuum from absolute truthfulness to absolute untruthfulness and …


Interactions Between A High Intensity Wildfire And An Atmopsheric Hydraulic Jump In The Case Of The 2023 Lahaina Fire, Clifford Dw Ehrke Jul 2025

Interactions Between A High Intensity Wildfire And An Atmopsheric Hydraulic Jump In The Case Of The 2023 Lahaina Fire, Clifford Dw Ehrke

Master's Theses

On 8 August 2023, a grass fire that started in the city of Lahaina, Hawai’i, grew into the deadliest wildfire in the United States since 1918. This wildfire offers a unique opportunity to explore the impact of high heat output on an atmospheric hydraulic jump and a downslope wind event. We conducted two WRF-SFIRE simulations to investigate these effects: one incorporating fire–atmosphere feedback and the other without it. We compare these WRF-SFIRE simulations to all available data regarding the fire event, including high resolution satellite data, weather station data from other parts of Maui and the Hawaiian Archipelago, and official …


Replicating Vignoles Et Al. Results On Multidimensional Self-Construal: Comparing The United States, East Asia, Southeast Asia, And Latin America, Jon Lorenz A. Lim Jul 2025

Replicating Vignoles Et Al. Results On Multidimensional Self-Construal: Comparing The United States, East Asia, Southeast Asia, And Latin America, Jon Lorenz A. Lim

Master's Theses

Contemporary research on self-construal indicates that people define and perceive themselves either as independent or interdependent. Self-construal scales have become the most common method to quantitatively measure both types of self-construal across the United States, East Asia, Southeast Asia, and Latin America. Multidimensional measures of the self tend to be more accurate in defining the self than earlier dichotomous scales. In general, European Americans and Latin Americans perceived themselves as independent and East and Southeast Asians as interdependent. In the current study, undergraduate European American, East Asian American, Southeast Asian American, and Latin American students from San Jose State University …


An Interpretative Phenomenological Analysis Of Black Female Swimmers' Experiences Of Belonging, Felicity E. Passon Jul 2025

An Interpretative Phenomenological Analysis Of Black Female Swimmers' Experiences Of Belonging, Felicity E. Passon

Master's Theses

Although swimming participation has grown in the United States, the experiences of Black female swimmers remain significantly underrepresented in academic literature. This study addresses that gap by exploring the lived experiences of Black women participating in Division 1 (D1) college swimming. Using Interpretative Phenomenological Analysis (IPA) and Black feminist thought, the research explored how Black female D1 swimmers experienced belonging in this underrepresented sport. Semi-structured interviews were conducted with nine D1 Black female swimmers, and six major themes illustrate the varied factors that shaped their experiences of belonging. Even with racially gendered barriers to inclusion, they identified strategies to foster …


Genotoxicity Assessment Of Conventional And Cad/Cam Denture Base Materials, Alanood Aldubayan Jul 2025

Genotoxicity Assessment Of Conventional And Cad/Cam Denture Base Materials, Alanood Aldubayan

Master's Theses (2009 -)

Aim: In prosthodontics, polymethyl methacrylate (PMMA) has been widely used. Their biocompatibility and potential genotoxicity remain a concern due to the residual monomer release. Computer-aided design and manufacturing (CAD/CAM) denture base materials have emerged and offered some improved mechanical and physical properties compared to the standard conventional heat-cured denture base material. However, their long-term biocompatibility remains unstudied. Therefore, this study evaluates the genotoxicity effects of conventional and CAD/CAM denture base materials on human gingival fibroblasts (HGFs). Methodology: Disk-shaped samples were fabricated of six denture base resins, including heat-cured PMMA, milled PMMA, and four 3D-printed resins. HGFs were exposed to the …


Beyond Scrolling: Social Media’S Impact On Creativity, Gabriel Owusu, Murad Moqbel Jul 2025

Beyond Scrolling: Social Media’S Impact On Creativity, Gabriel Owusu, Murad Moqbel

Information Systems Faculty Publications

Although prior research has explored social media’s impact on team creativity and knowledge management, its influence on individual creative performance remains understudied. Drawing on Transactive Memory Systems (TMS) theory, this research investigates how social media deep structure use affects individual creative performance through TMS dimensions: specialization, credibility, and coordination. We surveyed 362 U.S. active social media users, focusing on Facebook usage, and tested the hypothesized relationships using structural equation modeling. Findings reveal that social media deep structure use significantly influences TMS dimensions, which enhance creative performance through individual creative efficacy. This study extends TMS theory to individual creativity and introduces …


Staff Education To Improve Fall Prevention Practices In The Home Health Setting, Chinemelum Okoye Jul 2025

Staff Education To Improve Fall Prevention Practices In The Home Health Setting, Chinemelum Okoye

Walden Dissertations and Doctoral Studies

Falls among adults aged 65 and older represent a significant public health concern, as they are the leading cause of injury and hospitalization within this demographic. According to the Centers for Disease Control and Prevention (CDC), nearly one in four older adults experiences a fall annually, leading to over 3 million emergency department visits. In home health settings, the risk of falls is heightened due to uncontrolled environments and insufficient staff training. This quality improvement project assessed the effectiveness of an educational intervention aimed at fall prevention strategies for home health staff, including registered nurses (RNs) and certified nursing assistants …


Staff Education To Use The Teach-Back Method To Decrease Congestive Heart Failure Readmissions, Carlita Tucker Jul 2025

Staff Education To Use The Teach-Back Method To Decrease Congestive Heart Failure Readmissions, Carlita Tucker

Walden Dissertations and Doctoral Studies

This staff education project focused on educating staff to use the teach-back method to decrease congestive heart failure (CHF) readmissions. It is essential to address this issue within the context of nursing practice because CHF patients have left the hospital without adequate knowledge of their care plans, which compromised their self-care and increased their chances of returning to the hospital. This project employed the teach-back method, which is an effective communication process involving the patient reiterating what the staff has told them. The practice-focused question which guided the project was: For staff in an acute care hospital, will evidence-based training …


Evaluation Of Physical, Mental, And Mechanical Aspects Of An Extreme Military Training Event: A Continuous Monitoring Approach, Tirthankar Chatterjee, Debojyoti Bhattacharyya, Roshani Meena Jul 2025

Evaluation Of Physical, Mental, And Mechanical Aspects Of An Extreme Military Training Event: A Continuous Monitoring Approach, Tirthankar Chatterjee, Debojyoti Bhattacharyya, Roshani Meena

Journal of Human Performance in Extreme Environments

Soldiers receive extensive training at extremes of environments and simulated terrains to improve their battle efficiency. A study was designed to evaluate the actual cost of a military physical efficiency test consisting of several physically engaging activities to quantify physiological, mechanical, and subjective demands. Sixteen Indian soldiers participated in a military training session consisting of events such as a 5-km run, 4-m vertical rope climbing, a 2.75-m jump, a 60-m dash, and a 9-m horizontal rope climbing with 6.5 kg of equipment in a hot dry environment. Their physiological status was monitored continuously. National Aeronautics and Space Administration Task Load …


Assessing The Adversarial Robustness Of Multimodal Medical Ai Systems: Insights Into Vulnerabilities And Modality Interactions, Ekaterina Mozhegova, Asad Masood Khattak, Adil Khan, Roman Garaev, Bader Rasheed, Muhammad Shahid Anwar Jul 2025

Assessing The Adversarial Robustness Of Multimodal Medical Ai Systems: Insights Into Vulnerabilities And Modality Interactions, Ekaterina Mozhegova, Asad Masood Khattak, Adil Khan, Roman Garaev, Bader Rasheed, Muhammad Shahid Anwar

All Works

The emergence of both task-specific single-modality models and general-purpose multimodal large models presents new opportunities, but also introduces challenges, particularly regarding adversarial attacks. In high-stakes domains like healthcare, these attacks can severely undermine model reliability and their applicability in real-world scenarios, highlighting the critical need for research focused on adversarial robustness. This study investigates the behavior of multimodal models under various adversarial attack scenarios. We conducted experiments involving two modalities: images and texts. Our findings indicate that multimodal models exhibit enhanced resilience against adversarial attacks compared to their single-modality counterparts. This supports our hypothesis that the integration of multiple modalities …


Two Origins Of The Winter Subsidence In And Around The Arabian Peninsula, Muhammad Usman, Kosuke Heki Jul 2025

Two Origins Of The Winter Subsidence In And Around The Arabian Peninsula, Muhammad Usman, Kosuke Heki

All Works

Hydrological surface loads, such as snowpack and soil moisture, are the main drivers of seasonal crustal movements as seen by space geodetic techniques. In addition to that, seawater sometimes exerts additional forces for coastal stations, and the atmosphere often plays an important role for stations within continents. Here we report a case in and around the Arabian Peninsula. Despite little seasonal hydrological changes there, stations show fairly uniform seasonal vertical crustal movements, characterized by ~ 1 cm winter subsidence, over the entire region. We found that they are mainly driven by the atmospheric loading. Differences in their amplitudes are compensated …


Public Understanding Of And Engagement With Community Health Workers And Promotores De Salud: Findings From Two National Surveys, Elizabeth A. Rohan, Julie S. Townsend, Andrea Torres, Hope L. Thompson, Dawn M. Holman, Avid Reza, Felicia Solomon Tharpe, Erin Caple, Ashley Wennerstrom Jul 2025

Public Understanding Of And Engagement With Community Health Workers And Promotores De Salud: Findings From Two National Surveys, Elizabeth A. Rohan, Julie S. Townsend, Andrea Torres, Hope L. Thompson, Dawn M. Holman, Avid Reza, Felicia Solomon Tharpe, Erin Caple, Ashley Wennerstrom

School of Public Health Faculty Publications

INTRODUCTION: Community health workers (CHWs) can improve health by helping people navigate health care services and systems and connecting them to community services that address nonmedical factors such as food insecurity, housing, and transportation. While CHWs have long been part of the US public health system, there are no data, to our knowledge, on the public's familiarity and interactions with CHWs. METHODS: We analyzed data from the 2022 Porter Novelli FallStyles and Estilos surveys, online market research surveys of the general public delivered in English (FallStyles) or primarily Spanish (Estilos). Each survey asked the same 4 questions on familiarity and …


Deciphering The Apomixis Reproductive Trait And Its Manipulation Strategies To Enhance Crop Improvement, Mohd Razik Midin, Aiesyaa Majdiena Emlee, Mohamad Azimi Shaharudin, Fadzlin Qistina Fauzan, Siti Fatimah Zakaria, Emelda Rosseleena Rohani, Farah Ayuni Farinordin Jul 2025

Deciphering The Apomixis Reproductive Trait And Its Manipulation Strategies To Enhance Crop Improvement, Mohd Razik Midin, Aiesyaa Majdiena Emlee, Mohamad Azimi Shaharudin, Fadzlin Qistina Fauzan, Siti Fatimah Zakaria, Emelda Rosseleena Rohani, Farah Ayuni Farinordin

Turkish Journal of Botany

In plants, apomixis is the process of asexual reproduction when seeds are produced from the maternal tissues of the ovule. Gametophytic and sporophytic apomixis develop with distinctive mechanisms and are molecularly triggered either by hybridization or polyploidization. As apomixis involves meiosis suppression and parthenogenesis, these events are likely to be genetically driven. T he apomictic trait is associated with several genes that need a diploid or aneuploid gamete for their transfer in polyploid species. T he molecular mechanisms driving apomixis in various plant species have been explained by previous investigations into apomictic genes. Apomixis offers agronomic advantages, such as reducing …


Choline-An Essential Nutrient With Health Benefits And A Signaling Molecule, Brianne C. Burns, Jitendra D. Belani, Hailey N. Wittorf, Eugen Brailoiu, G. Cristina Brailoiu Jul 2025

Choline-An Essential Nutrient With Health Benefits And A Signaling Molecule, Brianne C. Burns, Jitendra D. Belani, Hailey N. Wittorf, Eugen Brailoiu, G. Cristina Brailoiu

College of Pharmacy Faculty Papers

Choline has been recognized as an essential nutrient involved in various physiological functions critical to human health. Adequate daily intake of choline has been established by the US National Academy of Medicine in 1998, considering choline requirements for different ages, sex differences and physiological states (e.g., pregnancy). By serving as a precursor for acetylcholine and phospholipids, choline is important for cholinergic transmission and the structural integrity of cell membranes. In addition, choline is involved in lipid and cholesterol transport and serves as a methyl donor after oxidation to betaine. Extracellular choline is transported across the cell membrane via various transport …


New York Law School Announces New Chair Of The Board Of Trustees, New York Law School Jul 2025

New York Law School Announces New Chair Of The Board Of Trustees, New York Law School

NYLS Community News

No abstract provided.


Biochemical And Proteomic Analyses Explain The Role Of Thiourea In Improving Tolerance Against Cadmium Toxicity In Maize, Mustafa Yildiz, Hakan Terzi̇, Nurgül Sönmez Jul 2025

Biochemical And Proteomic Analyses Explain The Role Of Thiourea In Improving Tolerance Against Cadmium Toxicity In Maize, Mustafa Yildiz, Hakan Terzi̇, Nurgül Sönmez

Turkish Journal of Botany

Thiourea (TU), a sulfur-containing compound, is recognized for its ability to ameliorate the deleterious impacts of metal ions on plant growth. Nonetheless, the molecular mechanisms by which TU regulates metabolic activities in maize (Zea mays L.) under cadmium (Cd) stress remain largely unexplored. This study seeks to clarify how TU (35 μM) mitigates or enhances tolerance to Cd toxicity (50 μM) through physiological and proteomic methods. Cd exposure resulted in inhibited plant growth, leaf chlorosis, and lipid peroxidation; however, the addition of TU reduced Cd toxicity by decreasing Cd accumulation and modulating antioxidant enzyme activity. The global proteome profile was …


Engagement Of Secondary History Social Science Teachers With Professional Development: A Phenomenological Study, Suzanne Paulazzo Jul 2025

Engagement Of Secondary History Social Science Teachers With Professional Development: A Phenomenological Study, Suzanne Paulazzo

Dissertations

Secondary social science teachers tend to feel disengaged and frustrated with their professional development (PD) experiences. They also feel that recommended meaningful practices appear to be time-consuming, require extra hours of preparation, and rely heavily on collaboration. Using phenomenological methodology, the dissertation research investigated secondary social science teachers' perceptions of their roles as educators, their professional growth, and their motivations for engaging in professional development opportunities. Nine male and one female teacher participants from a History-Social-Science Department in an urban public school in Northern California participated in an interview. This study addressed the following research questions: How do teachers perceive …


Effective Strategies To Reduce Silo Culture To Increase Financial Performance In Nonprofit Healthcare Organizations, Pedro E. Mendez Jul 2025

Effective Strategies To Reduce Silo Culture To Increase Financial Performance In Nonprofit Healthcare Organizations, Pedro E. Mendez

Walden Dissertations and Doctoral Studies

Silo culture in nonprofit healthcare organizations hinders knowledge sharing and communication, which can negatively affect financial performance. This issue is particularly important for healthcare leaders and policymakers seeking to enhance organizational efficiency and improve patient care quality. Grounded in the competing values framework, the purpose of this qualitative, pragmatic research project was to explore the effective strategies used by nonprofit healthcare human resources (HR) leaders to reduce silo culture and enhance financial performance. The participants included six HR executives at the vice president level or higher from nonprofit healthcare systems with more than 5,000 employees in the Southeastern United States. …


Resilience In Crisis: How Bipoc Educators Navigated The Challenges Associated With Covid-19, Racial Awakening, And The Move To Online Learning, Jannet Galicia Castrejon Jul 2025

Resilience In Crisis: How Bipoc Educators Navigated The Challenges Associated With Covid-19, Racial Awakening, And The Move To Online Learning, Jannet Galicia Castrejon

Dissertations

An unprecedented number of BIPOC teachers exited the profession since June 2020 largely due to the challenges posted by the COVID-19 pandemic (Doan et al., 2024). This study aimed to investigate ways these educators coped with the heavy toll of the converging pandemic(s) by asking what, if anything, sustained them? Participants provided individual and group testimonios and shared snapshots of what it was like to teach and exist during this time via the photovoice methodology and reflected on the challenges and sources of support. BIPOC teachers described the following challenges: difficulty connecting with kids, first-hand and vicarious trauma, increased workload, …


Conjugative Delivery Of Toxin Genes, Yang Grace Li, Daniel Haeusser, William Margolin, Peter J Christie Jul 2025

Conjugative Delivery Of Toxin Genes, Yang Grace Li, Daniel Haeusser, William Margolin, Peter J Christie

Faculty, Staff and Student Publications

The bacterial type IV secretion systems (T4SS) are medically problematic for their roles in the dissemination of mobile genetic elements or effector proteins, but they also have great potential for new antimicrobial therapies. Recent studies have deployed the T4SS subfamily of conjugation systems to deliver gene editing CRISPR/Cas systems to disrupt drug resistance genes or kill targeted bacterial recipients. However, the therapeutic potential of conjugative CRISPR/Cas delivery is compromised by mutations or host repair systems that diminish the efficiency with which CRISPR/Cas induces double-strand breaks in new transconjugants. Here, we compared the efficiencies of conjugation-based killing systems based on the …


Designing Well-Being Intervention Trials For People With Progressive Multiple Sclerosis: The Importance Of Understanding Usual Care Comparators, Marcia Finlayson, Silvia Poli, Federico Bozzoli, Giampaolo Brichetto, Lars Bø, Isolde Martina Busch, Ulrik Dalgas, Nikos Evangelou, Amanda Farrin, Jennifer Freeman, Helena Jidborg, Daphne Kos, Claudia H. Marck, Daniel Ontaneda, Jessica Podda, Michela Rimondini, Polly Swain, Emma Tallantyre, Lauren A. Taylor, Roshan Das Nair Jul 2025

Designing Well-Being Intervention Trials For People With Progressive Multiple Sclerosis: The Importance Of Understanding Usual Care Comparators, Marcia Finlayson, Silvia Poli, Federico Bozzoli, Giampaolo Brichetto, Lars Bø, Isolde Martina Busch, Ulrik Dalgas, Nikos Evangelou, Amanda Farrin, Jennifer Freeman, Helena Jidborg, Daphne Kos, Claudia H. Marck, Daniel Ontaneda, Jessica Podda, Michela Rimondini, Polly Swain, Emma Tallantyre, Lauren A. Taylor, Roshan Das Nair

School of Health Professions

Well-being captures an individual’s capacity to lead a mean ingful and engaged life. Interventions to address well-being go beyond managing symptoms or supporting daily activity performance. Designing trials to evaluate the effectiveness of such well-being interventions can be challenging. One such challenge is determining what the comparator or control arm should be. Several trials of complex interventions use usual care as a comparator, but this can be particularly challenging when planning trials across multiple countries and health care systems. Therefore, trial design decisions must be informed by a good understanding of what constitutes usual or routine well-being interventions across locations. …


Subscapularis Ct-Scan Evaluation In Patients With Proximal Humerus Fracture: Reverse Total Shoulder Arthroplasty Versus Hemi-Arthroplasty, Edoardo Gaj, Andrea Redler, Alessandro Maggiori, Susanna M. Pagnotta, Natale Criseo, Vikranth Mirle, Matthew Daggett, Angelo De Carli Jul 2025

Subscapularis Ct-Scan Evaluation In Patients With Proximal Humerus Fracture: Reverse Total Shoulder Arthroplasty Versus Hemi-Arthroplasty, Edoardo Gaj, Andrea Redler, Alessandro Maggiori, Susanna M. Pagnotta, Natale Criseo, Vikranth Mirle, Matthew Daggett, Angelo De Carli

GME Publications

Background/Objectives: Hemiarthroplasty (HA) and Reverse Total Shoulder Arthroplasty (RTSA) are both reliable treatment options for complex proximal humerus fractures. The role of the subscapularis tendon is well-defined in HA, whereas it plays a controversial role in RTSA. The purpose of our study is to evaluate its role in patients with proximal humerus fractures treated with HA and RTSA and investigate its association with clinical outcomes. Methods: Sixty-eight consecutive patients with proximal humeral fracture were prospectively enrolled into the study from June 2015 to May 2020 (RTSA = 36; HA = 32). Pre- and postoperative shoulder CT scans were …


Graduate Student Paper: Aging In A Changing Japan: Gendered Adaptation To Changing Family Structure, Miki Izu, Clayton Chalmers Jul 2025

Graduate Student Paper: Aging In A Changing Japan: Gendered Adaptation To Changing Family Structure, Miki Izu, Clayton Chalmers

Asia Pacific Perspectives

Although Japanese seniors are very healthy, research shows that they are not very happy. Compared to seniors in other developed countries, Japanese elders have lower ratings of subjective well-being and are increasingly alone. This paper argues that changes to Japanese family life help explain why Japanese elders are struggling with low subjective well-being. Specifically, declining marriage rates and declining rates of elders living with their children (co-residency) have made it harder for elders to get the support they need. Moreover, the effect and the adaptations to these changes are not equal between men and women. While elderly Japanese men are …


Cancer Screening Uptake And Usual Source Of Care Among Hispanic Survivors Of Adolescent And Young Adult Cancer, Eunju Choi, Amy M Berkman, Clark R Andersen, John M Salsman, Andrea C Betts, Joel Milam, Kimberly A Miller, Susan K Peterson, Qian Lu, Christabel K Cheung, Lauren V Ghazal, J A Livingston, Michelle A T Hildebrandt, Susan K Parsons, David R Freyer, Michael E Roth Jul 2025

Cancer Screening Uptake And Usual Source Of Care Among Hispanic Survivors Of Adolescent And Young Adult Cancer, Eunju Choi, Amy M Berkman, Clark R Andersen, John M Salsman, Andrea C Betts, Joel Milam, Kimberly A Miller, Susan K Peterson, Qian Lu, Christabel K Cheung, Lauren V Ghazal, J A Livingston, Michelle A T Hildebrandt, Susan K Parsons, David R Freyer, Michael E Roth

Faculty, Staff and Student Publications

Purpose: This study examines cancer screening rates and the usual source of care among Hispanic survivors of adolescent and young adult (AYA, aged 15-39) cancer, a group at increased risk for poor health outcomes, including secondary cancers.

Methods: National Health Interview Survey data were analyzed to identify Hispanic survivors of AYA cancer and Hispanic age- and sex-matched non-cancer controls. Breast, cervical, and colorectal screening (ever screened and up-to-date according to the U.S. Preventive Services Task Force recommendations) as well as reporting a usual source of care were compared among survivors and controls eligible for screening using multivariable logistic regressions.

Results: …


Survival-Inferred Fragility Of Statistical Significance In Phase Iii Oncology Trials, Alexander D Sherry, Yufei Liu, Pavlos Msaouel, Timothy A Lin, Alex Koong, Christine Lin, Joseph Abi Jaoude, Roshal R Patel, Ramez Kouzy, Molly B El-Alam, Avital M Miller, Mohannad Owiwi, Jonathan Ofer, David Bomze, Zachary R Mccaw, Tomer Meirson, Ethan B Ludmir Jul 2025

Survival-Inferred Fragility Of Statistical Significance In Phase Iii Oncology Trials, Alexander D Sherry, Yufei Liu, Pavlos Msaouel, Timothy A Lin, Alex Koong, Christine Lin, Joseph Abi Jaoude, Roshal R Patel, Ramez Kouzy, Molly B El-Alam, Avital M Miller, Mohannad Owiwi, Jonathan Ofer, David Bomze, Zachary R Mccaw, Tomer Meirson, Ethan B Ludmir

Faculty, Staff and Student Publications

In phase III oncology trials, superiority is defined by statistical significance using P thresholds. However, this approach has been criticized because P is continuous. Here, we reconstruct patient-level data for 230 phase III oncology trials to model the robustness of statistical significance by estimating the survival-inferred fragility index (SIFI), defined as the smallest number of patients changing arms that alters the statistical significance interpretation. The median SIFI was 8 patients (IQR 4-19), representing 1.4% of enrollments (IQR 0.7%-3%). As a continuous statistic, P-but not the significance interpretation-was correlated with SIFI. Moreover, overall survival endpoints were more fragile than surrogate endpoints. …


Minimal Ablative Margin Quantification Using Hepatic Arterial Versus Portal Venous Phase Ct For Colorectal Metastases Segmentation: A Dual-Center, Retrospective Analysis, Noreen S Siddiqi, Yuan-Mao Lin, Jessica Albuquerque Marques Silva, Gregor Laimer, Peter Schullian, Yannick Scharll, Alexandra M Dunker, Caleb S O'Connor, Kyle A Jones, Kristy K Brock, Reto Bale, Bruno C Odisio, Iwan Paolucci Jul 2025

Minimal Ablative Margin Quantification Using Hepatic Arterial Versus Portal Venous Phase Ct For Colorectal Metastases Segmentation: A Dual-Center, Retrospective Analysis, Noreen S Siddiqi, Yuan-Mao Lin, Jessica Albuquerque Marques Silva, Gregor Laimer, Peter Schullian, Yannick Scharll, Alexandra M Dunker, Caleb S O'Connor, Kyle A Jones, Kristy K Brock, Reto Bale, Bruno C Odisio, Iwan Paolucci

Faculty, Staff and Student Publications

Objective: To compare the predictive value of minimal ablative margin (MAM) quantification using tumor segmentation on intraprocedural contrast-enhanced hepatic arterial (HAP) versus portal venous phase (PVP) CT on local outcomes following percutaneous thermal ablation of colorectal liver metastases (CRLM).

Methods: This dual-center retrospective study included patients undergoing thermal ablation of CRLM with intraprocedural preablation and postablation contrast-enhanced CT imaging between 2009 and 2021. Tumors were segmented in both HAP and PVP CT phases using an artificial intelligence-based auto-segmentation model and reviewed by a trained radiologist. The MAM was quantified using a biomechanical deformable image registration process. The area under the …