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Articles 72301 - 72330 of 1730916
Full-Text Articles in Entire DC Network
Staff Education Program To Improve Nursing Knowledge On Fall Prevention Strategies, Chioma C. Achonye
Staff Education Program To Improve Nursing Knowledge On Fall Prevention Strategies, Chioma C. Achonye
Walden Dissertations and Doctoral Studies
In nursing practice, falls among adults aged 65 and above are a critical concern due to their potential to cause serious injuries and complications. As a result, fall prevention has become a top priority for healthcare providers striving to ensure patient safety and quality. The Doctor of Nursing Practice (DNP) project was designed to address the issue of falls in long-term care facilities by implementing a staff education program focused on patient fall risk assessment, identifying intrinsic and extrinsic factors influencing falls, and implementing evidence-based interventions. The DNP project practice-focused question was Does an education program on fall prevention strategies …
Staff Education To Improve Staff Knowledge On Preeclampsia, Doris Wanmban Fombo
Staff Education To Improve Staff Knowledge On Preeclampsia, Doris Wanmban Fombo
Walden Dissertations and Doctoral Studies
Preeclampsia is a disorder that usually develops after 20 weeks of pregnancy and can lead to serious adverse outcomes or death for the mother and fetus if not promptly diagnosed and managed. Hence, a staff education project was designed and implemented to enhance staff knowledge of preeclampsia. The practice problem was limited staff knowledge of preeclampsia a pregnancy complication that can affect both the mother and fetus. The practice-focused question explored whether a staff education project on preeclampsia affected office staff knowledge. The purpose of the project was to develop and implement a staff education program to improve staff knowledge …
Coming Out And Social Acceptance: Understanding Lgbtq Veterans' Minority Stressors, Conrado Augustine Martin
Coming Out And Social Acceptance: Understanding Lgbtq Veterans' Minority Stressors, Conrado Augustine Martin
Walden Dissertations and Doctoral Studies
This quantitative study explored the experiences of LGBTQ veterans residing in Ohio, examining the relationship between the coming out process, social acceptance, and minority stress. Lesbian, gay, bisexual, trans, and queer (LGBTQ) military veterans face higher rates of minority stressors, resulting in higher rates of suicidal ideation and mental health issues, which impact healthcare practices that affirm their identity. Discrimination, microaggressions, coming out, identity disclosure, and social belonging were identified as key contributing factors. Guided by Meyer’s minority stress theory, the study aimed to assess whether levels of outness, and identification with the LGBTQ community correlated with experiences of minority …
Grade Concept Paper 9: Rationale And Process For Creating A Grade Ontology, Paul Whaley, Brian Alper, Joanne Dehnbostel, Carlos Alva-Diaz, Stavros Antoniou, Antonio Bognanni, Javier Bracchiglione, Therese Kristine Dalsbø, Sean Grant, Jennifer Hunter, Alfonso Iorio, Malgorzata Lagisz, Harold Lehmann, Sheyu Li, Joerg Meerpohl, Saphia Mokrane, Cauê Monaco, Ignacio Neumann, Kevin Pottie, Shahab Sayfi, Nigar Sekercioglu, Jasvinder Singh, Bernardo Sousa-Pinto, Janice Tufte, Lenny Thinagaran Vasanthan, Li Wang, Jun Xia, Xiaomei Yao, Holger Schünemann
Grade Concept Paper 9: Rationale And Process For Creating A Grade Ontology, Paul Whaley, Brian Alper, Joanne Dehnbostel, Carlos Alva-Diaz, Stavros Antoniou, Antonio Bognanni, Javier Bracchiglione, Therese Kristine Dalsbø, Sean Grant, Jennifer Hunter, Alfonso Iorio, Malgorzata Lagisz, Harold Lehmann, Sheyu Li, Joerg Meerpohl, Saphia Mokrane, Cauê Monaco, Ignacio Neumann, Kevin Pottie, Shahab Sayfi, Nigar Sekercioglu, Jasvinder Singh, Bernardo Sousa-Pinto, Janice Tufte, Lenny Thinagaran Vasanthan, Li Wang, Jun Xia, Xiaomei Yao, Holger Schünemann
Faculty, Staff and Students Publications
Context: As the rate of research production accelerates, the ability to efficiently and unambiguously communicate judgments relating to the synthesis, evaluation, and use of scientific information becomes paramount.
Perspective: Scientific information can be viewed as a "layered infrastructure" of data, evidence, knowledge, and use. The GRADE approach serves as a de facto data standard for this infrastructure, supporting movement between layers by reducing ambiguity in claims to knowledge (in the form of judgements of certainty in the evidence when answering research questions) and level of commitment to possible solutions to problems (in the form of strength of recommendations for interventions). …
Nuak Kinases: Signaling Mechanisms And Therapeutic Applications, Nicole M. Cullen, Peter Rosston, Bakhtawar Tufail, Anne E. D'Armond, Ayushi Patel, Dara H. Khosravi, Bridgette M. Collins-Burow, Van T. Hoang, Elizabeth C. Martin, David H. Drewry, Matthew E. Burow, Suresh K. Alahari
Nuak Kinases: Signaling Mechanisms And Therapeutic Applications, Nicole M. Cullen, Peter Rosston, Bakhtawar Tufail, Anne E. D'Armond, Ayushi Patel, Dara H. Khosravi, Bridgette M. Collins-Burow, Van T. Hoang, Elizabeth C. Martin, David H. Drewry, Matthew E. Burow, Suresh K. Alahari
School of Medicine Faculty Publications
The novel (nua) kinases 1 and 2 are two of 12 AMP-activated protein–related kinases whose signaling pathways are involved in cancer progression, as well as neurologic, fibrotic, and inflammatory diseases. Currently, there are 80 Food and Drug Administration-approved kinase inhibitors which target roughly 24 of the 500+ known human kinases, leaving most kinases underexplored, including NUAK1 and NUAK2. Thus, there is a critical need for selective inhibition of NUAK1 and NUAK2 signaling. Here, we review the protein structure, known upstream regulators and downstream targets, and expression profiles of NUAK1 and NUAK2 in cancerous compared to noncancerous tissue. We also delineate …
“I Laughed Along For Years But Hated It Inside:” Understanding Nuance In Peer Teasing Experiences Using A Thematic Analysis, Naomi C.Z. Andrews, Molly Dawes Ph.D.
“I Laughed Along For Years But Hated It Inside:” Understanding Nuance In Peer Teasing Experiences Using A Thematic Analysis, Naomi C.Z. Andrews, Molly Dawes Ph.D.
Faculty Publications
Introduction
Peer teasing is ubiquitous, yet ambiguous in nature. Despite recent attempts to delineate and clarify differences in teasing experienced as playful versus harmful, there remains overlap and complexity in these interactions. In the current study, we present a conceptual model of teasing, which includes many nested features that dynamically interact within a teasing episode. Using this conceptual model to guide our work, the goal of the current study was to use qualitative inquiry to bring further conceptual clarity to the overlap between teasing that is experienced as playful versus harmful.
Method
Using semi-structured interviews, we asked university students ( …
Cone Vs. Vmat Srs Planning For Dual Targets: Effects Of Target Size, Separation, And Isocenter Displacement, Hannah Angeli
Cone Vs. Vmat Srs Planning For Dual Targets: Effects Of Target Size, Separation, And Isocenter Displacement, Hannah Angeli
Masters Projects
Objective: This study compares cone-based and volumetric modulated arc therapy (VMAT) stereotactic radiosurgery (SRS) planning for dual intracranial targets, examining the effects of target size, inter-target separation, and isocenter displacement on dosimetric outcomes. Methods: Plans were generated for spherical targets of 8.0 mm, 10.0 mm, and 12.0 mm diameters using both VMAT and cone-based techniques with single-isocenter configurations. Key metrics including maximum dose, volumes of normal brain receiving 12 Gy and 50% of the prescription dose (V12Gy, V50%), high-dose volume (V100%), gradient index, and target coverage were evaluated. Results: Cone-based plans demonstrated superior dose conformity and reduced normal tissue exposure …
Ancient Maya Crisis And Resilience, James Aimers
Ancient Maya Crisis And Resilience, James Aimers
Climate Change and the Individual, 2025-26
During the Maya Terminal Classic period (from about 750-1050 AD), many Maya sites in Mexico, Belize, Guatemala, and Honduras were abandoned. This radical change has been investigated for over 100 years, with drought and climate change recently given a central role. My research on the Maya collapse demonstrates great variability in the Terminal Classic, and not all sites were abandoned. In this lesson I focus on variability and resilience in the human response to climate change.
Survival To Hospital Discharge In The Fetus With Moderate To Severe Mitral Regurgitation Either In Isolation Or In Combination With Aortic Valve Stenosis Or Atresia, A Fetal Heart Society Collaborative Study, Betul Yilmaz Furtun, Kavitha Pundi, Anita Moon-Grady, Nicole Cresalia, Asela Nieuwsma, Sarah K Gelehrter, Bhawna Arya, Mary T Donofrio, Christopher Statile, Ann Kavanaugh-Mchugh, Lindsay Freud, Elijah Bolin, Megan Warner, Sowmya Balasubramanian, James Strainic, Carol Wittlieb-Weber, Nelangi M Pinto, Lisa Hornberger, Shaine A Morris
Survival To Hospital Discharge In The Fetus With Moderate To Severe Mitral Regurgitation Either In Isolation Or In Combination With Aortic Valve Stenosis Or Atresia, A Fetal Heart Society Collaborative Study, Betul Yilmaz Furtun, Kavitha Pundi, Anita Moon-Grady, Nicole Cresalia, Asela Nieuwsma, Sarah K Gelehrter, Bhawna Arya, Mary T Donofrio, Christopher Statile, Ann Kavanaugh-Mchugh, Lindsay Freud, Elijah Bolin, Megan Warner, Sowmya Balasubramanian, James Strainic, Carol Wittlieb-Weber, Nelangi M Pinto, Lisa Hornberger, Shaine A Morris
Faculty, Staff and Students Publications
Background: Case series report high mortality after fetal diagnosis of moderate to severe mitral regurgitation in combination with left atrial dilation, hydrops, or restrictive atrial septum. However, overall outcomes and specific high-risk features remain unclear.
Methods: We performed a multicenter retrospective cohort study of fetuses with ≥moderate mitral regurgitation and normal cardiac connections evaluated January 1, 2005 to January 31, 2016. Fetuses undergoing fetal cardiac intervention (FCI) were described separately. We assessed associations between fetal echocardiographic features and discharge mortality using mixed logistic regression and classification and regression tree modeling, stratified by studies performed < 28 and ≥28 weeks gestational age (GA).
Results: Of 67 fetuses, 96% had …
Development And Validation Of Venous Thromboembolism-Bidirectional Encoder Representations From Transformers (Vte-Bert) Natural Language Processing Model, Omid Jafari, Shengling Ma, Barbara D Lam, Jun Y Jiang, Emily Zhou, Mrinal Ranjan, Justine Ryu, Raka Bandyo, Arash Maghsoudi, Bo Peng, Christopher I Amos, Abiodun Oluyomi, Nathanael R Fillmore, Jennifer La, Ang Li
Development And Validation Of Venous Thromboembolism-Bidirectional Encoder Representations From Transformers (Vte-Bert) Natural Language Processing Model, Omid Jafari, Shengling Ma, Barbara D Lam, Jun Y Jiang, Emily Zhou, Mrinal Ranjan, Justine Ryu, Raka Bandyo, Arash Maghsoudi, Bo Peng, Christopher I Amos, Abiodun Oluyomi, Nathanael R Fillmore, Jennifer La, Ang Li
Faculty, Staff and Students Publications
Background: Accurate and rapid phenotyping of venous thromboembolism (VTE) in longitudinal studies is important. A natural language processing (NLP) tool externally validated in representative patients is lacking.
Objectives: To train and validate an efficient NLP model to detect incident VTE event.
Methods: We designed a novel NLP platform, NLPMed, to assist thrombosis researchers with data preprocessing, phenotype annotation, language model finetuning, and NLP application. Using clinical notes, discharge summaries, and radiology reports from patients with cancer at 2 healthcare institutions, we finetuned Bio_Clinical Bidirectional Encoder Representations from Transformers (BERT) to develop VTE-BERT. The new model was trained to detect acute …
Leishmania In Texas: A Contemporary One Health Scoping Review Of Vectors, Reservoirs, And Human Health, Morgan H Jibowu, Richard Chung, Nina L Tang, Sarah Guo, Leigh-Anne Lawton, Brendan J Sullivan, Dawn M Wetzel, Sarah M Gunter
Leishmania In Texas: A Contemporary One Health Scoping Review Of Vectors, Reservoirs, And Human Health, Morgan H Jibowu, Richard Chung, Nina L Tang, Sarah Guo, Leigh-Anne Lawton, Brendan J Sullivan, Dawn M Wetzel, Sarah M Gunter
Faculty, Staff and Students Publications
Leishmaniasis, a vector-borne neglected tropical disease, affects over 6.2 million people globally. Case acquisition is increasingly recognized in the United States, and in Texas, most reported cases are locally acquired and speciated to Leishmania mexicana. We conducted a scoping literature review to systematically assess contemporary research on Leishmania in humans, animals, reservoir hosts, or vectors in Texas after 2000. Out of 22 eligible studies, the most prevalent themes were case reports, followed by studies on domestic animals, reservoirs, and vectors, with several studies bridging multiple disciplines. Climate change, urbanization, and habitat encroachment appear to be driving the northward expansion …
Real-Time Experiences Of Racism And Stress In Association With Postpartum Weight Retention: A Longitudinal Ecological Momentary Assessment Study, Dara M Méndez, Amanda L Tapia, Sarah A Sanders, Andrea D Casas, Marquita Smalls, Esa M Davis, Stephen L Rathbun, Tiffany L Gary-Webb, Lora E Burke, Serwaa S Omowale, Linda A Adodoadji, John J Gianakas, Y Lai, Maisa Feghali, Meredith L Wallace
Real-Time Experiences Of Racism And Stress In Association With Postpartum Weight Retention: A Longitudinal Ecological Momentary Assessment Study, Dara M Méndez, Amanda L Tapia, Sarah A Sanders, Andrea D Casas, Marquita Smalls, Esa M Davis, Stephen L Rathbun, Tiffany L Gary-Webb, Lora E Burke, Serwaa S Omowale, Linda A Adodoadji, John J Gianakas, Y Lai, Maisa Feghali, Meredith L Wallace
Faculty, Staff and Student Publications
Racial inequities in postpartum weight have been documented with limited studies on the influences of racism and other forms of discrimination. In a prospective longitudinal study applying ecological momentary assessment (EMA) and ambulatory assessment of weight, we measured the association between discrimination, stress, and postpartum weight change. The Postpartum Mothers Mobile Study is a cohort of 313 pregnant and birthing individuals who were followed during their second and third trimesters through 1 year postpartum. They were recruited in clinical settings between 2017 and 2020 in a major city center in Pennsylvania. Measures of racism and gender-based discrimination were collected via …
Decreasing Emergency Department (Ed) Revisits: Providing Resources That Address Overutilization For Patients With Substance Use Disorder, Amber May
Doctor of Nursing Practice Final Project Abstract
Date of Doctor of Nursing Practice Project Completion
Summer 8-5-2025
Faculty Advisor
Rebecca Tsusaki PhD, APRN-CNP, WHNP-BC, IBCLC
ABSTRACT
PURPOSE This quality improvement project was intended to decrease emergency department (ED) revisits by 10%, from high-utilizer patients (those with more than 10 ED visits in the past year), by implementing community health worker–led follow-up phone calls within one week of discharge, over a 30-day period. The project was conducted at a large metropolitan hospital in Houston, Texas.
BACKGROUND Non-urgent revisits and overutilization affect ED wait times, are associated with overcrowding, contribute to unnecessary care delays, impact patient satisfaction scores, and …
Improving Medication Adherence Among Patients With Anxiety, Abong Miyeh
Improving Medication Adherence Among Patients With Anxiety, Abong Miyeh
Walden Dissertations and Doctoral Studies
Addres+D14sing medication non-adherence among patients with anxiety disorders is crucial in nursing practice due to its significant impact on patient outcomes and healthcare costs. This doctoral project explores the effectiveness of staff education in enhancing nurses' skills in promoting medication adherence within this population. The practice-focused question for this project is "What evidence supports the effectiveness of a staff education program in increasing nursing staff knowledge about evidence-based strategies for improving medication adherence among patients with anxiety disorders?" The purpose of this doctoral project is to investigate the effectiveness of staff education interventions in improving medication adherence among individuals with …
The Impact Of Socio-Emotional And Provider Support On Hiv Testing In Southern United States, Ijeoma Onyinyechi Nwazuruokeh
The Impact Of Socio-Emotional And Provider Support On Hiv Testing In Southern United States, Ijeoma Onyinyechi Nwazuruokeh
Walden Dissertations and Doctoral Studies
HIV was first diagnosed over 40 years ago in the United States; however, HIV remains an epidemic. An understanding of how socio-emotional support, social isolation, and support from an individual's provider influence HIV testing in the Southern United States can be a key to increasing testing rates and ultimately reducing the incidence and prevalence of HIV in the Southern United States. The purpose of this non-experimental quantitative study was to examine the relationship between HIV testing, socio-emotional support, and social isolation, and how these variables are further moderated by an individual having provider support in the Southern United States. The …
Staff Education To Improve Knowledge Of The Patient Health Questionnaire-9 Assessment, Josie Weber
Staff Education To Improve Knowledge Of The Patient Health Questionnaire-9 Assessment, Josie Weber
Walden Dissertations and Doctoral Studies
This doctoral project was focused on a staff education initiative to enhance the proper use of the Patient Health Questionnaire-9 (PHQ-9), a validated depression screening tool, in an outpatient behavioral health (OBH) clinic. Despite its clinical utility, the PHQ-9 is often underused or inconsistently applied due to knowledge gaps among nursing staff. Inconsistent screening can delay diagnosis and treatment, negatively affecting patient outcomes. I conducted this project to address these gaps by implementing structured training to promote high-quality, patient-centered care. The practice-focused question was: Does a structured PHQ-9 training session improve staff knowledge in an outpatient behavioral health clinic, as …
Faculty And Administrators' Perspectives Of Generative Artificial Intelligence At An Online Higher Education Institution, Devon Edmund
Faculty And Administrators' Perspectives Of Generative Artificial Intelligence At An Online Higher Education Institution, Devon Edmund
Walden Dissertations and Doctoral Studies
The problem addressed in this study was that faculty and administrators in higher education are not prepared to address the use of generative artificial intelligence (GAI) innovations in institutional policies and practices. The pace of advancement of GAI in higher education (HE) left institutions to determine policies and practices without industry best practices or guidelines established by accreditors or regulatory bodies. The purpose of this qualitative study was to explore the perspectives of faculty and administrators at an online HE institution on how to respond to the emergence of GAI through institutional policies and practices. The theory supporting the study …
Helping Families Learn About Social Emotional Learning, Madalyn Ross
Helping Families Learn About Social Emotional Learning, Madalyn Ross
Masters Projects
Having developmentally appropriate social-emotional skills is an essential component of a growing child, yet many children lack the social-emotional skills necessary to be successful in the classroom. Families play an important role in the development of a child, but research shows that there are significant gaps in the knowledge and use of social-emotional learning (SEL) that families have. This project explores the importance of family involvement and knowledge surrounding SEL by looking at certain aspects that hinder SEL growth, such as trauma and excessive screen time, and aspects that help children excel in SEL development, such as teacher education and …
Association Between Allostatic Load And Accelerated White Matter Brain Aging: Findings From The Uk Biobank, Li Feng, Zhenyao Ye, Zewen Du, Yezhi Pan, Travis Canida, Hongjie Ke, Song Liu, Shuo Chen, L Elliot Hong, Peter Kochunov, Jie Chen, David K Y Lei, Edmond Shenassa, Tianzhou Ma
Association Between Allostatic Load And Accelerated White Matter Brain Aging: Findings From The Uk Biobank, Li Feng, Zhenyao Ye, Zewen Du, Yezhi Pan, Travis Canida, Hongjie Ke, Song Liu, Shuo Chen, L Elliot Hong, Peter Kochunov, Jie Chen, David K Y Lei, Edmond Shenassa, Tianzhou Ma
Faculty, Staff and Student Publications
White matter (WM) brain age, a neuroimaging-derived biomarker indicating WM microstructural changes, helps predict dementia and neurodegenerative disorder risks. The cumulative effect of chronic stress on WM brain aging remains unknown. In this study, we assessed cumulative stress using a multi-system composite allostatic load (AL) index based on inflammatory, anthropometric, respiratory, lipidemia, and glucose metabolism measures, and investigated its association with WM brain age gap (BAG), computed from diffusion tensor imaging data using a machine learning model, among 22 951 European ancestries aged 40 to 69 (51.40% women) from UK Biobank. Linear regression, Mendelian randomization, along with inverse probability weighting, …
Perspectives On Career Advising At A Large Private Religious Institution, Lane Toshio Muranaka
Perspectives On Career Advising At A Large Private Religious Institution, Lane Toshio Muranaka
Theses and Dissertations
This study examines the role of career advising at Brigham Young University (BYU), a faith-based institution where professional guidance focuses on spiritual development and purpose-driven learning. Through qualitative interviews with career advisors across various disciplines, the research explores how advisors define student success, integrate faith into their advising practices, and support students in aligning their career aspirations with personal meaning and the university's religious mission. Grounded in the belief that holistic education fosters lifelong success, BYU emphasizes the development of the "total person," including moral and spiritual dimensions. Findings reveal that student success is not solely measured by employment outcomes …
The Emergence Of An Object Of Regulatory Concern: The European Union’S Artificial Intelligence Act, Galán, Alexis, Schmidt, Rebecca
The Emergence Of An Object Of Regulatory Concern: The European Union’S Artificial Intelligence Act, Galán, Alexis, Schmidt, Rebecca
Santa Clara Journal of International Law
No abstract provided.
Metabolic Dysfunction-Associated Steatotic Liver Disease In People With Type 1 Diabetes., Brynlee Vermillion, Yuanjie Mao
Metabolic Dysfunction-Associated Steatotic Liver Disease In People With Type 1 Diabetes., Brynlee Vermillion, Yuanjie Mao
Ambulatory and Primary Care Articles
Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized as a significant comorbidity in individuals with type 1 diabetes (T1D), despite its historical association with type 2 diabetes. This review focuses on summarizing current findings regarding the role of insulin resistance in the development of MASLD in T1D, as well as examining the relationship between MASLD and diabetes-related complications. We will also briefly discuss the prevalence, diagnostic challenges, associated complications, and potential mechanisms underlying MASLD in T1D. Although insulin resistance is well established in MASLD among those with type 2 diabetes, its role in T1D requires further clarification. Emerging markers, …
Examining The Factor Structure And Correlates Of The Flourishing-At-Work Scale In United States School Psychologists, Nikita Pike
Examining The Factor Structure And Correlates Of The Flourishing-At-Work Scale In United States School Psychologists, Nikita Pike
Electronic Theses and Dissertations Archive
Despite moderate levels of stress and burnout in their work, school psychologists in the United States tend to be satisfied with their jobs. Although researchers have addressed why school psychologists view their work as important, there is yet another important feature of the workplace that has not been examined in this population: flourishing at work. This study aimed to enhance the understanding of flourishing at work in school psychologists by examining an existing scale, the Flourishing-at-Work Scale, completed online by a national sample of United States school psychologists. Data from a sample of 369 practicing school psychologists were used in …
Examining The Active Ingredients In An Anti-Stigma Intervention For Individuals With A Criminal History, Kaylee Cook
Examining The Active Ingredients In An Anti-Stigma Intervention For Individuals With A Criminal History, Kaylee Cook
Electronic Theses and Dissertations Archive
Obtaining employment is key to successful reintegration for people who have been incarcerated. However, employers are often hesitant to hire formerly incarcerated persons due to general negative attitudes toward them and concern that they will not exhibit positive work behaviors. Interventions to reduce general types of stigma exist, with primary strategies involving education and/or contact. Most research examining the effectiveness of stigma-reducing strategies largely focus on reducing identity-based stigma (e.g., race, mental illness), with limited research on reducing choice-based stigma, such as those with criminal histories. However, regardless of targeted stigma, there is no consensus regarding which intervention format (i.e., …
Predictors Of Sanction Length Following Correctional Disciplinary Hearings: The Role Of Individual Characteristics, Misconduct Type, And Placement In Segregation, Jade Renee Horton
Predictors Of Sanction Length Following Correctional Disciplinary Hearings: The Role Of Individual Characteristics, Misconduct Type, And Placement In Segregation, Jade Renee Horton
Electronic Theses and Dissertations Archive
Misconduct by incarcerated individuals is a significant threat to institutional safety. While research has highlighted discrepancies in who engages or who is reported as engaging in misconduct and suggests staff biases may impact disciplinary decisions, available research tends to narrowly focus on the use of disciplinary segregation as an outcome and often neglects other potential disciplinary outcomes that are less serious and the predictors of those outcomes. The current study examined predictors of the seriousness of outcomes, measured in length (weeks) of imposed sanction, of disciplinary hearings. It was hypothesized that those who are identified as Black, with a serious …
Three Essays In Forward-Looking Statements, Social Media Collaboration, And Climate Talents, Jing-Chi Chen
Three Essays In Forward-Looking Statements, Social Media Collaboration, And Climate Talents, Jing-Chi Chen
Electronic Theses and Dissertations Archive
This dissertation consists of three essays on Forward-Looking Statements (FLS), Social Media Collaboration, and Climate Talents. The first essay examines how FLS impact investor trading behavior and market liquidity. We find that FLS are associated with reductions in investor trading costs, largely driven by lower market-maker inventory costs. FLS also associate with increased market depth on both sides of the bid-ask spread and greater retail and institutional trading activity, with retail investors being more responsive. Cross-sectional tests show these associations are stronger during market downturns and when earnings guidance is absent. Results are robust to instrumental variable regressions using managerial …
Extreme Value Theory View Of High Emitter Diesel Vehicles In The Us From 1991 To 2021, M. Matti Maricq, Gary A. Bishop
Extreme Value Theory View Of High Emitter Diesel Vehicles In The Us From 1991 To 2021, M. Matti Maricq, Gary A. Bishop
Fuel Efficiency Automobile Test Publications
Extreme value theory (EVT) is a statistical method to characterize the tails of distributions, such as high emitter vehicle emissions. The present work addresses the United States (US) diesel fleet. EVT confirms that high emitters contribute disproportionately to adverse air quality. It further reveals that high emitter emissions have responded differently to progressively tighter emissions standards compared to fleet averages. Carbon monoxide (CO) and hydrocarbons (HC) high emitter emissions fell in concert with the fleet average after widespread implementation of the diesel oxidation catalyst to meet US Environmental Protection Agency (EPA) Tier 1 emissions standards, but remained unchanged after introduction …
Supporting Young Learners With Disabilities In Inclusive Classrooms: A Toolkit For General Education Teachers, Emily M. Raleigh
Supporting Young Learners With Disabilities In Inclusive Classrooms: A Toolkit For General Education Teachers, Emily M. Raleigh
Masters Projects
Many young elementary students with disabilities often experience difficulty maintaining engagement in their learning and managing their emotions in general education classrooms. These challenges can have a negative influence on their ability to interact with their peers, develop foundational academic skills, and feel a sense of belonging. At the same time, many general educators report a lack of effective training, strategies, and confidence in implementing supports to students with disabilities, particularly in the areas of self-regulation and engagement. This project responds to this issue through the creation of a visual support toolkit developed for use in inclusive early elementary classrooms. …
Announcing The 2025 Induction Of Members Into The Accounting Hall Of Fame, American Accounting Association
Announcing The 2025 Induction Of Members Into The Accounting Hall Of Fame, American Accounting Association
Accounting Hall of Fame Brochures
No abstract provided.
Phase 2 Study Of Zilovertamab Vedotin In Participants With Metastatic Solid Tumors, Funda Meric-Bernstam, Martin Gutierrez, Enrique Sanz-Garcia, Diego Villa, Jun Zhang, Jennifer Friedmann, Fengting Yan, Mark A Socinski, John Sarantopoulos, Luis E Raez, Quincy S Chu, Maxime Chénard-Poirier, Manash Chatterjee, Hong Ren, Qi Liu, Douglas A Levine, Komal L Jhaveri
Phase 2 Study Of Zilovertamab Vedotin In Participants With Metastatic Solid Tumors, Funda Meric-Bernstam, Martin Gutierrez, Enrique Sanz-Garcia, Diego Villa, Jun Zhang, Jennifer Friedmann, Fengting Yan, Mark A Socinski, John Sarantopoulos, Luis E Raez, Quincy S Chu, Maxime Chénard-Poirier, Manash Chatterjee, Hong Ren, Qi Liu, Douglas A Levine, Komal L Jhaveri
Faculty, Staff and Student Publications
Purpose: Zilovertamab vedotin, an antibody‒drug conjugate targeting receptor tyrosine kinase‒like orphan receptor 1 (ROR1), had manageable safety and promising antitumor activity in participants with relapsed or refractory non-Hodgkin lymphomas. We evaluated zilovertamab vedotin in participants with previously-treated metastatic solid tumors.
Methods: This phase 2, open-label, nonrandomized study (NCT04504916) enrolled participants with metastatic triple-negative breast cancer, hormone receptor‒positive (HR+) breast cancer, nonsquamous non‒small-cell lung cancer, platinum-resistant ovarian cancer, or pancreatic cancer. Participants received zilovertamab vedotin ≤2.5 mg/kg once every 3 weeks (Q1/3W) or < 1.75 mg/kg twice every 3 weeks (Q2/3W). Primary endpoint was objective response rate (ORR) per RECIST v1.1 by blinded independent central review. ROR1 protein expression was correlated with clinical outcomes.
Results: 102 participants were enrolled (Q1/3W, n=70; Q2/3W, n=32). ORR was 1% (95% CI, 0%‒8%) with …