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Kernel Principal Component Analysis And Convolutional Neural Network-Based Approach For Obstructive Sleep Apnoea Detection Using Electrocardiogram, Aida Noor Indrawati, Nuryani Nuryani, Wiharto Wiharto, Diah Kurnia Mirawati, Trio Pambudi Utomo, Nanang Wiyono Aug 2025

Kernel Principal Component Analysis And Convolutional Neural Network-Based Approach For Obstructive Sleep Apnoea Detection Using Electrocardiogram, Aida Noor Indrawati, Nuryani Nuryani, Wiharto Wiharto, Diah Kurnia Mirawati, Trio Pambudi Utomo, Nanang Wiyono

Iraqi Journal for Computer Science and Mathematics

Obstructive Sleep Apnoea (OSA) is a prevalent sleep disorder characterised by repeated episodes of partial or complete upper airway obstruction during sleep, primarily due to the relaxation and collapse of soft tissues in the throat. These interruptions lead to disrupted sleep patterns and reduced oxygen saturation, increasing the risk of cardiovascular complications. Although Polysomnography (PSG) is considered the gold standard for diagnosing OSA, it is often uncomfortable for patients due to the extensive use of sensors and prolonged monitoring duration. As a result, there is a growing need for alternative diagnostic methods that are more efficient, comfortable, and cost-effective. This …


Iraqi’S Car License Plate Recognition Based On Deep Learning, Mushreq Abdulhussain Shuriji, Husam Al-Behadili, Hadel A. Hussain Aug 2025

Iraqi’S Car License Plate Recognition Based On Deep Learning, Mushreq Abdulhussain Shuriji, Husam Al-Behadili, Hadel A. Hussain

Iraqi Journal for Computer Science and Mathematics

Vehicle license plate recognition is essential due to the rising number of operational cars, which leads to an increasing difficulty of this task even for humans. Systems for car license recognition normally consist of two branch systems, namely, license plate recognition and license plate detection. The aim of the detection part is to pinpoint the car and the position of its license plate, while the objective of the recognition part is to recognize characters on that plate. In this work, the emphasis is on Arabic car license plates. In this category of plates, there are three lines containing numerals and …


Retracted: High-Performance System For Predicting Icu Patient Durations Using Artificial Neural Networks With Transfer Learning, Mahmood. K. Awsaj, Yousif Al Mashhadany, Lamia Chaarifourati Aug 2025

Retracted: High-Performance System For Predicting Icu Patient Durations Using Artificial Neural Networks With Transfer Learning, Mahmood. K. Awsaj, Yousif Al Mashhadany, Lamia Chaarifourati

Iraqi Journal for Computer Science and Mathematics

In the wake of disease outbreaks such as COVID-19, real-time health monitoring and prediction systems have become essential for ensuring effective patient care. These systems rely on sensors to monitor biometric parameters such as blood pressure, body temperature, and heart rate, providing continuous and accurate data that medical staff cannot collect manually around the clock. This study presents a robust framework for managing Intensive Care Unit (ICU) patients using Artificial Neural Networks (ANN) with Transfer Learning. The data is analyzed across five distinct time windows, each representing a period of ICU stay based on vital signs and medical test results. …


Reframing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Me/Cfs): Biological Basis Of Disease And Recommendations For Supporting Patients., Priya Agarwal, Kenneth J Friedman Aug 2025

Reframing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Me/Cfs): Biological Basis Of Disease And Recommendations For Supporting Patients., Priya Agarwal, Kenneth J Friedman

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a worldwide challenge. There are an estimated 17-24 million patients worldwide, with an estimated 60 percent or more who have not been diagnosed. Without a known cure, no specific curative medication, disability lasting years to being life-long, and disagreement among healthcare providers as to how to most appropriately treat these patients, ME/CFS patients are in need of assistance. Appropriate healthcare provider education would increase the percentage of patients diagnosed and treated; however, in-school healthcare provider education is limited. To address the latter issue, the New Jersey Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Association (NJME/CFSA) has developed …


Occupational Therapy’S Impact On Heart Failure Readmission Rates In The Acute Care Setting, Morgan Breen Aug 2025

Occupational Therapy’S Impact On Heart Failure Readmission Rates In The Acute Care Setting, Morgan Breen

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.


The Minutes Of The Marshall University Board Of Governors Meeting, August 05, 2025, Marshall University Board Of Governors Aug 2025

The Minutes Of The Marshall University Board Of Governors Meeting, August 05, 2025, Marshall University Board Of Governors

Board of Governors Minutes

No abstract provided.


Dopaminergic Neurons In The Zebrafish Subpallium Belong To The Extended Medial Amygdala, Daniel Armbruster, Thomas Mueller, Wolfgang Driever Aug 2025

Dopaminergic Neurons In The Zebrafish Subpallium Belong To The Extended Medial Amygdala, Daniel Armbruster, Thomas Mueller, Wolfgang Driever

Department of Biology Faculty Scholarship and Creative Works

The amygdala is a heterogeneous, multinuclear telencephalic structure critical for motivated and emotion-related behaviors in vertebrates. In ray-finned fish (Actinopterygii) like the teleost zebrafish, a telencephalic outward-growing process called eversion makes defining amygdaloid territories particularly challenging. Teleosts are also peculiar in that they develop numerous dopaminergic (DA) neurons in the subpallium, while in tetrapods, such populations are less prominent or appear only transiently. To shed light on the organization of the amygdala in teleosts, we pursued an evolutionary developmental approach focusing on the topological origin of subpallial DA neurons. Specifically, we analyzed the distribution of tyrosine hydroxylase (Th) in conjunction …


Establishing Operational Foundations In A Faculty-Led Clinic: Workflow Design, Role Development, And Service Planning, Rebecca Wensmann Aug 2025

Establishing Operational Foundations In A Faculty-Led Clinic: Workflow Design, Role Development, And Service Planning, Rebecca Wensmann

DNP Projects

A Central Minnesota College, in collaboration with local community partners, sought to provide access to medical care for an underserved population while offering opportunities for graduate and undergraduate nursing education. They achieved this by establishing a faculty-led clinic in a high-poverty level area in Central Minnesota, where nearly 7% of the population under the age of 65 lacked health insurance (U.S. Census Bureau, 2024). Research was completed on clinic workflows and processes, as well as many interviews with clinics and community members throughout Minnesota. With this data, a clinic workflow, job description list, and services offered were created. This information …


A Dosimetric Comparison Of 6 Mv And 10 Mv Beam Energies For Adrenal Sbrt, Mariel A. Lewis Aug 2025

A Dosimetric Comparison Of 6 Mv And 10 Mv Beam Energies For Adrenal Sbrt, Mariel A. Lewis

Masters Projects

Purpose This study aims to compare the dosimetric performance of 6 MV and 10 MV photon beam energies in stereotactic body radiation therapy (SBRT) for adrenal tumors. Given the anatomical complexity of the adrenal region and its proximity to critical organs, optimizing beam energy selection is essential to maximize tumor control while minimizing normal tissue toxicity. Methods and Materials A retrospective study analysis was conducted using treatment plans from ten patients with adrenal metastases. Each case was planned with volumetric modulated arc therapy (VMAT) using both 6 MV and 10 MV beam energies. Dosimetric metrics assessed included target coverage, conformity …


Socioeconomic Determinants Of Depression And Anxiety Disorders In Puerto Ricans Living On The Island And The Mainland, Herman Alvarado Aug 2025

Socioeconomic Determinants Of Depression And Anxiety Disorders In Puerto Ricans Living On The Island And The Mainland, Herman Alvarado

Walden Dissertations and Doctoral Studies

Research shows that, among Hispanics, depression and anxiety disorders are the two most prevalent mental disorders, particularly for Puerto Ricans. The socioecological model approaches mental health conditions from a perspective where multiple levels in society influence health-related behaviors. Based on this approach, this quantitative study looked at how socioeconomic factors - marital status, education, employment, and residential status were related to a diagnosis of depression or anxiety in Puerto Ricans. This study also explored whether there were differences between two groups of Puerto Ricans: those living on the island compared to those living in the 50 states. Analysis was conducted …


Smart Manufacturing In Chemicals, Shehan S. Makani Aug 2025

Smart Manufacturing In Chemicals, Shehan S. Makani

STEM for Success Showcase

The chemical and pharmaceutical manufacturing sectors are evolving toward intelligent, adaptive production systems. This white paper explores how AI-enabled machinery and connected equipment are transforming chemical process efficiency, product quality, and sustainability. Drawing from conceptual case studies at ChemRich USA and ChemeNova LLC, we propose a framework where AI models interface with real-time machine data from centrifuges, filters, reactors, and mixers to enhance formulation, reduce downtime, and enable on-demand customization. The result is a more agile, data-driven, and sustainable manufacturing paradigm.


Hybrid Nanomaterials, Composites Thereof, And Uses Thereof, Manoj Kumar Ram Aug 2025

Hybrid Nanomaterials, Composites Thereof, And Uses Thereof, Manoj Kumar Ram

USF Patents

Described herein are hybrid nanomaterials that can include a functionalized nanodiamond and a functionalized graphene and/or functionalized graphene oxide. Also described herein are composite materials that can include a hybrid nanomaterial described herein and a polymer or polymeric material. Also described herein are methods of making and using the hybrid nanomaterials and composite materials described herein.


Flexible Monolithic All Polycrystalline Silicon Carbide Neural Interface Device And Method Of Manufacture, Stephen Edward Saddow, Francesco La Via, Christopher Leroy Frewin Aug 2025

Flexible Monolithic All Polycrystalline Silicon Carbide Neural Interface Device And Method Of Manufacture, Stephen Edward Saddow, Francesco La Via, Christopher Leroy Frewin

USF Patents

An implantable, conformal, neural interface device fabricated completely from neuro-compatible SiC and method of manufacture thereof, includes at least one elongated probe to be placed in a brain of a subject of interest, the at least one elongated probe comprising a plurality of electrodes positioned on a surface of the elongated probe, each of the plurality of electrodes comprising a conductive mesa consisting of polycrystalline silicon carbide (SiC), an insulative layer consisting of amorphous SiC, the insulative layer positioned to surround the conductive mesa absent a window through the amorphous SiC exposing a surface of the conductive mesa. The elongated …


Batched Query Processing And Optimization, Yicheng Tu, Mehrad Eslami Aug 2025

Batched Query Processing And Optimization, Yicheng Tu, Mehrad Eslami

USF Patents

Disclosed are various embodiments for batched query processing and optimization in database management systems. A single algebraic expression is generated based at least in part on applying equivalence rules to algebraic expressions for a plurality of database queries of a database comprising a set of relations. The equivalence rules involve relational operators comprising Psi (ψ) operators. The database can be queried using a single database query to create a result that is equivalent to the plurality of database queries.


Comparison Of 10 Mv Flattening Filter And Flattening Filter-Free Volumetric Modulated Art Therapy (Vmat) Radiation Plans In Partial Breast Irradiation: Evaluating Dose Sparing To The Left Anterior Descending Coronary Artery, Jillian Beliew Aug 2025

Comparison Of 10 Mv Flattening Filter And Flattening Filter-Free Volumetric Modulated Art Therapy (Vmat) Radiation Plans In Partial Breast Irradiation: Evaluating Dose Sparing To The Left Anterior Descending Coronary Artery, Jillian Beliew

Masters Projects

Importance Minimizing radiation dose to the heart, particularly the left anterior descending coronary artery (LAD), is essential in left-sided partial breast irradiation (PBI). Flattening filter-free (FFF) beam configurations may improve organ-at-risk (OAR) sparing and treatment efficiency.

Objective To compare dosimetric outcomes between 10 MV flattening filter (FF) and 10 MV flattening filter-free (FFF) VMAT plans in patients receiving accelerated partial breast irradiation (APBI), focusing on LAD dose sparing.

Design, Setting, and Participants This retrospective dosimetric study included 10 patients with early-stage, left-sided breast cancer. Each patient had two VMAT plans generated using identical geometry and constraints in Eclipse v16.01: one …


Acquisitions Unit Annual Report 2024-2025, Andrée J. Rathemacher Aug 2025

Acquisitions Unit Annual Report 2024-2025, Andrée J. Rathemacher

Technical Services Reports and Statistics

Annual Report of the Acquisitions Unit, University Libraries, University of Rhode Island for FY2025. Covers personnel, work flow, special projects, and serial, monograph, and e-resource acquisitions. Supplemental files include data on library materials expenditures by a number of variables as well as important working documents from the year.


Consequences Of The Double Empathy Problem Within The Clinical Environment: A New Model For Neuroinclusive Care, Sofia Jimenez Aug 2025

Consequences Of The Double Empathy Problem Within The Clinical Environment: A New Model For Neuroinclusive Care, Sofia Jimenez

Theses and Dissertations

As diagnoses of autism spectrum disorder (ASD) rise, the neurodiversity and autistic self-advocacy movements have challenged traditional deficit-based clinical models and called for more inclusive, affirming approaches to care. Recent research disputes the long-held belief that autistic individuals have deficits in perspective-taking, revealing that miscommunication between autistic and neurotypical individuals results from mutual misunderstanding, a concept known as the double empathy problem (DEP; Milton, 2012), with the triple empathy problem (TEP) extending this framework to healthcare settings. Our study investigates the consequences of the DEP and TEP within clinical environments, focusing on interactions between neurotypical speech-language pathologists (SLPs) and adult …


Coding For Nonstandard Channels: A Capacity-Oriented Approach, J Daniel Harman Aug 2025

Coding For Nonstandard Channels: A Capacity-Oriented Approach, J Daniel Harman

Theses and Dissertations

This work addresses the issue of coding for non-standard channel models with an emphasis on capacity-oriented channel analysis and system design. The first channel studied is the Wyner wiretap channel. Channel sounding results were obtained to calculate the capacity for the multi-antenna case of the Wyner wiretap channel to ascertain the potential for secure communication via secrecy coding. The second channel studied is an asymmetric binary crossover erasure channel (ABCEC) with a short-blocklength constraint. The capacity for this channel was derived, and linear codes were chosen and tested. Another study was conducted on the ABCEC within a degraded wiretap channel …


Opening The Black-Box Of Mental Disorders: An Actor-Network Theory Analysis Of Schizophrenia, Brandalyn Morris Aug 2025

Opening The Black-Box Of Mental Disorders: An Actor-Network Theory Analysis Of Schizophrenia, Brandalyn Morris

McNair Scholars Manuscripts

Schizophrenia is a poorly understood mental dysfunction. It is culturally specific and encompasses several disease entities that defy robust classification. Using a few of the methodological notions from Bruno Latour’s Actor-Network Theory (ANT), this research seeks to disambiguate schizophrenia. The scope and focus of this examination will be restricted to three actors/actants within the assemblage of this mental disorder. By appropriating tools and terminology from ANT to reveal human and non-human actors and actants within the DSM classification system, the medical model of mental illness, and psychopharmacology, the objective of this research is to describe how the current concept of …


Genetic Overlap Between Functional Impairment And Depression And Anxiety Symptom Severity: Evidence From The Glad Study, Megan Skelton, Jessica Mundy, Abigail Ter Kuile, Brett Adey, Cherie Armour, Joshua Buckman, Jonathan Coleman, Molly Davies, Colette R. Hirsch, Matthew Hotopf, Ian Jones, Gursharan Kalsi, Georgina Krebs, Sang Hyuck Lee, Yuhao Lin, Andrew M. Mcintosh, Alicia J. Peel, Christopher Rayner, Katharine Rimes, Daniel J. Smith, Katherine N. Thompson, David Veale, James T.R. Walters, Christopher Hübel, Gerome Breen, Thalia C. Eley Aug 2025

Genetic Overlap Between Functional Impairment And Depression And Anxiety Symptom Severity: Evidence From The Glad Study, Megan Skelton, Jessica Mundy, Abigail Ter Kuile, Brett Adey, Cherie Armour, Joshua Buckman, Jonathan Coleman, Molly Davies, Colette R. Hirsch, Matthew Hotopf, Ian Jones, Gursharan Kalsi, Georgina Krebs, Sang Hyuck Lee, Yuhao Lin, Andrew M. Mcintosh, Alicia J. Peel, Christopher Rayner, Katharine Rimes, Daniel J. Smith, Katherine N. Thompson, David Veale, James T.R. Walters, Christopher Hübel, Gerome Breen, Thalia C. Eley

School of Psychology

BACKGROUND: Functional impairment in daily activities, such as work and socializing, is part of the diagnostic criteria for major depressive disorder and most anxiety disorders. Despite evidence that symptom severity and functional impairment are partially distinct, functional impairment is often overlooked. To assess whether functional impairment captures diagnostically relevant genetic liability beyond that of symptoms, we aimed to estimate the heritability of, and genetic correlations between, key measures of current depression symptoms, anxiety symptoms, and functional impairment.

METHODS: In 17,130 individuals with lifetime depression or anxiety from the Genetic Links to Anxiety and Depression (GLAD) Study, we analyzed total scores …


How Much Has The Recognition Of Women Artists’ Contributions To Art History Changed In The Past Half Century And Why?, Roger Clark Aug 2025

How Much Has The Recognition Of Women Artists’ Contributions To Art History Changed In The Past Half Century And Why?, Roger Clark

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.


Staff Education Program To Improve Nursing Knowledge On Fall Prevention Strategies, Chioma C. Achonye Aug 2025

Staff Education Program To Improve Nursing Knowledge On Fall Prevention Strategies, Chioma C. Achonye

Walden Dissertations and Doctoral Studies

In nursing practice, falls among adults aged 65 and above are a critical concern due to their potential to cause serious injuries and complications. As a result, fall prevention has become a top priority for healthcare providers striving to ensure patient safety and quality. The Doctor of Nursing Practice (DNP) project was designed to address the issue of falls in long-term care facilities by implementing a staff education program focused on patient fall risk assessment, identifying intrinsic and extrinsic factors influencing falls, and implementing evidence-based interventions. The DNP project practice-focused question was Does an education program on fall prevention strategies …


Staff Education To Improve Staff Knowledge On Preeclampsia, Doris Wanmban Fombo Aug 2025

Staff Education To Improve Staff Knowledge On Preeclampsia, Doris Wanmban Fombo

Walden Dissertations and Doctoral Studies

Preeclampsia is a disorder that usually develops after 20 weeks of pregnancy and can lead to serious adverse outcomes or death for the mother and fetus if not promptly diagnosed and managed. Hence, a staff education project was designed and implemented to enhance staff knowledge of preeclampsia. The practice problem was limited staff knowledge of preeclampsia a pregnancy complication that can affect both the mother and fetus. The practice-focused question explored whether a staff education project on preeclampsia affected office staff knowledge. The purpose of the project was to develop and implement a staff education program to improve staff knowledge …


Coming Out And Social Acceptance: Understanding Lgbtq Veterans' Minority Stressors, Conrado Augustine Martin Aug 2025

Coming Out And Social Acceptance: Understanding Lgbtq Veterans' Minority Stressors, Conrado Augustine Martin

Walden Dissertations and Doctoral Studies

This quantitative study explored the experiences of LGBTQ veterans residing in Ohio, examining the relationship between the coming out process, social acceptance, and minority stress. Lesbian, gay, bisexual, trans, and queer (LGBTQ) military veterans face higher rates of minority stressors, resulting in higher rates of suicidal ideation and mental health issues, which impact healthcare practices that affirm their identity. Discrimination, microaggressions, coming out, identity disclosure, and social belonging were identified as key contributing factors. Guided by Meyer’s minority stress theory, the study aimed to assess whether levels of outness, and identification with the LGBTQ community correlated with experiences of minority …


Grade Concept Paper 9: Rationale And Process For Creating A Grade Ontology, Paul Whaley, Brian Alper, Joanne Dehnbostel, Carlos Alva-Diaz, Stavros Antoniou, Antonio Bognanni, Javier Bracchiglione, Therese Kristine Dalsbø, Sean Grant, Jennifer Hunter, Alfonso Iorio, Malgorzata Lagisz, Harold Lehmann, Sheyu Li, Joerg Meerpohl, Saphia Mokrane, Cauê Monaco, Ignacio Neumann, Kevin Pottie, Shahab Sayfi, Nigar Sekercioglu, Jasvinder Singh, Bernardo Sousa-Pinto, Janice Tufte, Lenny Thinagaran Vasanthan, Li Wang, Jun Xia, Xiaomei Yao, Holger Schünemann Aug 2025

Grade Concept Paper 9: Rationale And Process For Creating A Grade Ontology, Paul Whaley, Brian Alper, Joanne Dehnbostel, Carlos Alva-Diaz, Stavros Antoniou, Antonio Bognanni, Javier Bracchiglione, Therese Kristine Dalsbø, Sean Grant, Jennifer Hunter, Alfonso Iorio, Malgorzata Lagisz, Harold Lehmann, Sheyu Li, Joerg Meerpohl, Saphia Mokrane, Cauê Monaco, Ignacio Neumann, Kevin Pottie, Shahab Sayfi, Nigar Sekercioglu, Jasvinder Singh, Bernardo Sousa-Pinto, Janice Tufte, Lenny Thinagaran Vasanthan, Li Wang, Jun Xia, Xiaomei Yao, Holger Schünemann

Faculty, Staff and Students Publications

Context: As the rate of research production accelerates, the ability to efficiently and unambiguously communicate judgments relating to the synthesis, evaluation, and use of scientific information becomes paramount.

Perspective: Scientific information can be viewed as a "layered infrastructure" of data, evidence, knowledge, and use. The GRADE approach serves as a de facto data standard for this infrastructure, supporting movement between layers by reducing ambiguity in claims to knowledge (in the form of judgements of certainty in the evidence when answering research questions) and level of commitment to possible solutions to problems (in the form of strength of recommendations for interventions). …


Nuak Kinases: Signaling Mechanisms And Therapeutic Applications, Nicole M. Cullen, Peter Rosston, Bakhtawar Tufail, Anne E. D'Armond, Ayushi Patel, Dara H. Khosravi, Bridgette M. Collins-Burow, Van T. Hoang, Elizabeth C. Martin, David H. Drewry, Matthew E. Burow, Suresh K. Alahari Aug 2025

Nuak Kinases: Signaling Mechanisms And Therapeutic Applications, Nicole M. Cullen, Peter Rosston, Bakhtawar Tufail, Anne E. D'Armond, Ayushi Patel, Dara H. Khosravi, Bridgette M. Collins-Burow, Van T. Hoang, Elizabeth C. Martin, David H. Drewry, Matthew E. Burow, Suresh K. Alahari

School of Medicine Faculty Publications

The novel (nua) kinases 1 and 2 are two of 12 AMP-activated protein–related kinases whose signaling pathways are involved in cancer progression, as well as neurologic, fibrotic, and inflammatory diseases. Currently, there are 80 Food and Drug Administration-approved kinase inhibitors which target roughly 24 of the 500+ known human kinases, leaving most kinases underexplored, including NUAK1 and NUAK2. Thus, there is a critical need for selective inhibition of NUAK1 and NUAK2 signaling. Here, we review the protein structure, known upstream regulators and downstream targets, and expression profiles of NUAK1 and NUAK2 in cancerous compared to noncancerous tissue. We also delineate …


“I Laughed Along For Years But Hated It Inside:” Understanding Nuance In Peer Teasing Experiences Using A Thematic Analysis, Naomi C.Z. Andrews, Molly Dawes Ph.D. Aug 2025

“I Laughed Along For Years But Hated It Inside:” Understanding Nuance In Peer Teasing Experiences Using A Thematic Analysis, Naomi C.Z. Andrews, Molly Dawes Ph.D.

Faculty Publications

Introduction

Peer teasing is ubiquitous, yet ambiguous in nature. Despite recent attempts to delineate and clarify differences in teasing experienced as playful versus harmful, there remains overlap and complexity in these interactions. In the current study, we present a conceptual model of teasing, which includes many nested features that dynamically interact within a teasing episode. Using this conceptual model to guide our work, the goal of the current study was to use qualitative inquiry to bring further conceptual clarity to the overlap between teasing that is experienced as playful versus harmful.

Method

Using semi-structured interviews, we asked university students ( …


Cone Vs. Vmat Srs Planning For Dual Targets: Effects Of Target Size, Separation, And Isocenter Displacement, Hannah Angeli Aug 2025

Cone Vs. Vmat Srs Planning For Dual Targets: Effects Of Target Size, Separation, And Isocenter Displacement, Hannah Angeli

Masters Projects

Objective: This study compares cone-based and volumetric modulated arc therapy (VMAT) stereotactic radiosurgery (SRS) planning for dual intracranial targets, examining the effects of target size, inter-target separation, and isocenter displacement on dosimetric outcomes. Methods: Plans were generated for spherical targets of 8.0 mm, 10.0 mm, and 12.0 mm diameters using both VMAT and cone-based techniques with single-isocenter configurations. Key metrics including maximum dose, volumes of normal brain receiving 12 Gy and 50% of the prescription dose (V12Gy, V50%), high-dose volume (V100%), gradient index, and target coverage were evaluated. Results: Cone-based plans demonstrated superior dose conformity and reduced normal tissue exposure …


Ancient Maya Crisis And Resilience, James Aimers Aug 2025

Ancient Maya Crisis And Resilience, James Aimers

Climate Change and the Individual, 2025-26

During the Maya Terminal Classic period (from about 750-1050 AD), many Maya sites in Mexico, Belize, Guatemala, and Honduras were abandoned. This radical change has been investigated for over 100 years, with drought and climate change recently given a central role. My research on the Maya collapse demonstrates great variability in the Terminal Classic, and not all sites were abandoned. In this lesson I focus on variability and resilience in the human response to climate change.


Survival To Hospital Discharge In The Fetus With Moderate To Severe Mitral Regurgitation Either In Isolation Or In Combination With Aortic Valve Stenosis Or Atresia, A Fetal Heart Society Collaborative Study, Betul Yilmaz Furtun, Kavitha Pundi, Anita Moon-Grady, Nicole Cresalia, Asela Nieuwsma, Sarah K Gelehrter, Bhawna Arya, Mary T Donofrio, Christopher Statile, Ann Kavanaugh-Mchugh, Lindsay Freud, Elijah Bolin, Megan Warner, Sowmya Balasubramanian, James Strainic, Carol Wittlieb-Weber, Nelangi M Pinto, Lisa Hornberger, Shaine A Morris Aug 2025

Survival To Hospital Discharge In The Fetus With Moderate To Severe Mitral Regurgitation Either In Isolation Or In Combination With Aortic Valve Stenosis Or Atresia, A Fetal Heart Society Collaborative Study, Betul Yilmaz Furtun, Kavitha Pundi, Anita Moon-Grady, Nicole Cresalia, Asela Nieuwsma, Sarah K Gelehrter, Bhawna Arya, Mary T Donofrio, Christopher Statile, Ann Kavanaugh-Mchugh, Lindsay Freud, Elijah Bolin, Megan Warner, Sowmya Balasubramanian, James Strainic, Carol Wittlieb-Weber, Nelangi M Pinto, Lisa Hornberger, Shaine A Morris

Faculty, Staff and Students Publications

Background: Case series report high mortality after fetal diagnosis of moderate to severe mitral regurgitation in combination with left atrial dilation, hydrops, or restrictive atrial septum. However, overall outcomes and specific high-risk features remain unclear.

Methods: We performed a multicenter retrospective cohort study of fetuses with ≥moderate mitral regurgitation and normal cardiac connections evaluated January 1, 2005 to January 31, 2016. Fetuses undergoing fetal cardiac intervention (FCI) were described separately. We assessed associations between fetal echocardiographic features and discharge mortality using mixed logistic regression and classification and regression tree modeling, stratified by studies performed < 28 and ≥28 weeks gestational age (GA).

Results: Of 67 fetuses, 96% had …