Digital Commons Network^™

Transdiagnostic Alterations In White Matter Microstructure Associated With Suicidal Thoughts And Behaviours In The Enigma Suicidal Thoughts And Behaviours Consortium, Laura S. Van Velzen, Alexander S. Hatoum, Et Al.

2020-Current year OA Pubs

No abstract provided.

Radiome: An Automated Home-Based Radio, Music Playlist, And Diary Reminder System: Report On Recruitment, Music Compilation, And Listening, And Preliminary Testing Of Heart Rate Activated Music, Alexander Street, Paul Fernie, Jorg Christfried Fachner, Patrizia Di Campli San Vito, Nicolas Farina, Ming Hung Hsu, Leonardo Muller, Stephen Brewster, Sube Banerjee, Alexis Kirke, Hari Shaji, Paulo Itaborai, Eduardo Reck Miranda

Peninsula Medical School

Background: One of the leading reasons for early admission to a care home in dementia is the escalation of neuropsychiatric symptoms (NPS), and music listening can help regulate these symptoms.Aims: RadioMe was a project designed for people living at home with dementia to build a system to help them maintain the highest quality of life there for as long as possible, with three functional components: 1. Streaming radio; 2. Providing pre-recorded spoken diary reminders; 3. interrupting the radio with pre-compiled playlists when a wrist-worn heart rate (HR) monitor detects stress. This article reports on the first two stages of this …

Perfusion Assessment In Ceus Imaging For Estimating Pancreatic Cancer Response To Sonoporation-Enhanced Chemotherapy., Omri Adler, Priscilla Machado, Trang Vu, Flemming Forsberg, Odd Helge Gilja, Dan Adam

Department of Radiology Faculty Papers

Accurate assessment of perfusion in vital organs like the pancreas is crucial for monitoring various pathologies, particularly tumors and their growth. While tumor growth inhibition usually results in decreased vascularization, current techniques for non-invasive and cost-effective perfusion assessment lack sufficient vessel separability for pancreatic applications, hindering optimal treatment selection and monitoring. Ultrasound (US) imaging offers advantages like low cost, rapid acquisition, non-invasiveness, and non-ionizing radiation. However, speckle, patient-related and acquisition-related motion artifacts, and limitations in distinguishing contrast-enhanced blood vessels, particularly in single frames, pose significant challenges. This study presents a novel solution utilizing image analysis of US contrast agents (UCAs) …

Over 30 Million And Growing: Child Development Accounts Around The World, Li Zou, Michael Sherraden

Center for Social Development Research

This report discusses the global reach and origins of Child Development Account policies, documenting impacts on approximately 32 million children worldwide. The policies range from Singapore’s comprehensive asset-building framework to Kazakhstan’s pioneering National Fund for Children. The seven policies highlighted here represent growing efforts to provide structured and lifelong asset-building across the full population, beginning as early as birth.

This report was updated in January 2026 to correct typographical errors in the monetary figures reported for South Korea.

Setdb1 Is Critically Required For Uveal Melanoma Growth And Represents A Promising Therapeutic Target, Imène Krossa, Céline Pisibon, Yann Cheli, Karine Bille, Mélanie Dalmasso, Sabah Hamadat, Chrystel Husser, Marie Irondelle, Julien Cherfils-Vicini, Frédéric Soysouvanh, Sacha Nahon-Esteve, Arnaud Martel, Sandra Lassalle, Jean-Pierre Caujolle, Célia Maschi, Stéphanie Baillif, Dan Hasson, Saul Carcamo, Andrerw E. Aplin, Irwin Davidson, Emily Bernstein, Valeria Naim, Robert Ballotti, Corine Bertolotto, Thomas Strub

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Metastatic uveal melanomas are highly resistant to all existing treatments. To identify actionable vulnerabilities, we conducted a CRISPR-Cas9 knockout screen using a library composed of chromatin regulators. We revealed that the lysine methyltransferase, SETDB1, plays a critical role in metastatic uveal melanoma cell proliferation and survival. Functionally, SETDB1 deficiency induces a DNA damage response, senescence-like state and growth arrest. Knockdown of SETDB1 is associated with a decreased expression of genes related to replication and cell cycle. Moreover, deficiency in CDC6, an essential regulator of DNA replication, phenocopies SETDB1 inhibition. Using a pre-clinical model, we further demonstrated that anti-SETDB1 therapy impairs …

Jar Seminar: Iconohistory By Dr. Severin Fowles, Dr. Severin Fowles

LAII Events

Friday, October 24 at 12:00 PM

Anthropology 248

The history of colonialism in the American West is not just the story of how European people, animals, and technologies invaded Indigenous worlds but also of how these things were engaged, redeployed, countered, rejected, and, in some cases, embraced by native communities. In this paper, I look beyond the horses, guns, germs, and steel that have dominated materialist analyses of the colonial encounter to consider the circulation of images—or more precisely, the circulation of new understandings of what images are and how they function. My focus is on the “Biographic Tradition,” an …

Mixed Quantum/Classical Theory For Rotational Excitation Of Hdo In Collisions With H2: Symmetry Breaking Effects And Time-Dependent Dynamics, Carolin Joy, Igor Gaidai, Alexandre Faure, Dmitri Babikov

Chemistry Faculty Research and Publications

The application of the mixed quantum/classical theory of inelastic scattering (MQCT) to the rotational excitation of the isotopically substituted water molecule, HDO, in collisions with hydrogen molecules is presented. Modification of the potential energy surface of thewater + hydrogen system, due to isotopic substitution, is described, and the effect of symmetry breaking is explored. It is found that the additional terms of potential expansion are significant and, therefore, are expected to play an important role during the collision process. The modeling of HDO + H₂ collision is carried out using both the MQCT method and the full-quantum CC method …

Invisible Aircraft In U.S. Airspace: Regulatory Gaps And Mid-Air Collision Risk For Part 121 Operators, Philip Vandette

International Journal of Aviation, Aeronautics, and Aerospace

Scheduled air carrier aircraft operate at large and small commercial airports across the U.S. National Airspace System. These turbine-powered aircraft fly at high speeds during departure and approach, yet many commercial airports are not covered by regulations requiring general aviation aircraft to transmit their positions, and some remain exempt from existing requirements. This regulatory gap forces airline pilots to rely on see-and-avoid methods that are impractical at turbine aircraft speeds. This study conducts a quantitative exploratory analysis of three data sources, using a PRISMA-style flow diagram, to examine the frequency of near mid-air collisions involving airline and general aviation aircraft …

Diabetes-Related Stigma, Hemoglobin A1c, And Psychological And Behavioral Outcomes Among Adults With Type 2 Diabetes In Ghana: A Structural Equation Modeling Approach, Samuel Akyirem

Sigma Foundation for Nursing Research Grant Reports

The findings from this grant-funded study have established a strong foundation for future research on the psychosocial aspects of diabetes care in low- and middle-income countries. Specifically, the project has generated preliminary evidence supporting the mediating role of psychological outcomes in the relationship between diabetes-related stigma and glycemic control. These results will inform the design of future longitudinal and intervention studies aimed at reducing stigma and improving mental health among people with diabetes in Ghana and across Africa. Additionally, the study has built local research capacity by training research assistants in advanced data collection and analysis methods, fostering a sustainable …

Beyond The Diagnosis: Creativity, Compassion, And Clinical Insight In Dental Education, Casper Jonker, Lambert Sofia, Sema Halis, Leah Harper, Wendy Smith

Peninsula Dental School

No abstract provided.

The Mosaic, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Transdiagnostic Alterations In White Matter Microstructure Associated With Suicidal Thoughts And Behaviours In The Enigma Suicidal Thoughts And Behaviours Consortium, Laura S Van Velzen, Lejla Colic, Zuriel Ceja, Maria R Dauvermann, Luca M Villa, Hannah S Savage, Yara J Toenders, Niousha Dehestani, Alyssa H Zhu, Adrian I Campos, Lauren E Salminen, Martin Alda, Ingrid Agartz, Nina Alexander, Rosa Ayesa-Arriola, Elizabeth D Ballard, Nerisa Banaj, Carlotta Barkhau, Zeynep Başgöze, Jochen Bauer, Francesco Benedetti, Klaus Berger, Bianca Besteher, Katharina Brosch, Manuel Canal-Rivero, Simon Cervenka, Romain Colle, Colm G Connolly, Emmanuelle Corruble, Philippe Courtet, Baptiste Couvy-Duchesne, Benedicto Crespo-Facorro, Kathryn R Cullen, Udo Dannlowski, Jeremy Deverdun, Ana M Diaz-Zuluaga, Lorielle M F Dietze, Jennifer W Evans, Negar Fani, Kira Flinkenflügel, Naomi P Friedman, Ian H Gotlib, Nynke A Groenewold, Dominik Grotegerd, Tomas Hajek, Alexander S Hatoum, Marco Hermesdorf, Ian B Hickie, Yoshiyuki Hirano, Tiffany C Ho, Yuki Ikemizu, Frank Iorfino, Jonathan C Ipser, Yuko Isobe, Andrea P Jackowski, Fabrice Jollant, Tilo Kircher, Melissa Klug, Sheri-Michelle Koopowitz, Anna Kraus, Axel Krug, Emmanuelle Le Bars, Elisabeth J Leehr, Meng Li, Elizabeth T C Lippard, Carlos Lopez-Jaramillo, Ivan I Maximov, Andrew M Mcintosh, Katie A Mclaughlin, Sean R Mcwhinney, Susanne Meinert, Elisa Melloni, Philip B Mitchell, Benson Mwangi, Igor Nenadić, Stener Nerland, Emilie Olie, Victor Ortiz-García De La Foz, Pedro M Pan, Fabricio Pereira, Fabrizio Piras, Federica Piras, Sara Poletti, Andrew E Reineberg, Gloria Roberts, Rafael Romero-García, Matthew D Sacchet, Giovanni A Salum, Anca-Larisa Sandu, Carl M Sellgren, Eiji Shimizu, Harry R Smolker, Jair C Soares, J Douglas Steele, Frederike Stein, Dan J Stein, Benjamin Straube, Lea Teutenberg, Florian Thomas-Odenthal, Paula Usemann, Romain Valabregue, Johanna Valencia-Echeverry, Gerd Wagner, Gordon Waiter, Martin Walter, Heather C Whalley, Mon-Ju Wu, Tony T Yang, Carlos A Zarate, Andre Zugman, Giovana B Zunta-Soares, Kees Van Heeringen, Sanne J H Van Rooij, Nic Van Der Wee, Steven Van Der Werff, Paul M Thompson, Hilary P Blumberg, Anne-Laura Van Harmelen, Miguel E Rentería, Neda Jahanshad, Enigma Suicidal Thoughts And Behaviours Consortium, Lianne Schmaal

Faculty, Staff and Student Publications

Previous studies have suggested that alterations in white matter (WM) microstructure are implicated in suicidal thoughts and behaviours (STBs). However, findings of diffusion tensor imaging (DTI) studies have been inconsistent. In this large-scale mega-analysis conducted by the ENIGMA Suicidal Thoughts and Behaviours (ENIGMA-STB) consortium, we examined WM alterations associated with STBs. Data processing was standardised across sites, and resulting WM microstructure measures (fractional anisotropy (FA), axial diffusivity (AD), mean diffusivity and radial diffusivity) for 24 WM tracts and one global measure were pooled across 40 cohorts. We compared these measures among individuals with a psychiatric diagnosis and lifetime history of …

Leptin As A Key Driver For Organ Fibrogenesis, Xue-Nan Sun, Shiuhwei Chen, Shangang Zhao, Jan-Bernd Funcke, Megan Virostek, Line Pedersen, Chao Li, Chanmin Joung, Qian Lin, Yan Li, Ayanna Cobb, May-Yun Wang, Kyounghee Min, Lisandro Maya-Ramos, Giovanna Degasperi, Junquan Liu, Ningyan Zhang, Zhiqiang An, Diana R Tomchick, R Max Wynn, Da Young Oh, Philipp E Scherer

Faculty, Staff and Student Publications

Leptin, a hormone primarily secreted by adipocytes, regulates energy balance and systemic metabolism through its interaction with the leptin receptor (LEPR). Beyond these functions, leptin signaling has been implicated in the pathogenesis of tissue fibrosis. Here, we report the x-ray crystal structures of a leptin-neutralizing antibody (hLep3) in the unbound and leptin-bound states. The interaction of this antibody with leptin mimics the interaction of the LEPR with leptin, providing direct insights into the mechanism by which the antibody disrupts leptin signaling. We furthermore evaluate the therapeutic potential of neutralizing leptin with this antibody across distinct mouse models of fibrosis affecting …

Assessment Of Long-Term Endocrine Sequelae Of Completion (2-Stage) Versus Total (Single-Stage) Pancreatectomy: A Multi-Institutional Research Network And Single-Institution Analysis, Michael Chang, Matthew Kraft, Zachary Kaplan, Harish Lavu, Charles Yeo, Wilbur Bowne, Avinoam Nevler

Department of Surgery Faculty Papers

BACKGROUND: Total pancreatectomy can be associated with severe endocrine complications. This study compares endocrine outcomes of patients who underwent a single-stage total pancreatectomy versus a 2-stage completion pancreatectomy.

METHODS: We used data from a multi-institutional research network (TriNetX), which identified 1,079 propensity score-matched total pancreatectomy and completion pancreatectomy patient pairs for age, gender, and race. These data were validated by a single-center review of a prospectively maintained database of 1,600 pancreatectomies, from which 88 completion and total pancreatectomy patients treated between 2013 and 2023 were identified. The primary endpoints were postoperative rates of hypoglycemia and diabetic ketoacidosis during the first …

Observing System Needs For Understanding Carbon–Climate Feedbacks, Dustin Carroll, Nicholas C. Parazoo, Nicole S. Lovenduski, Michael Keller, David S. Schimel, A. Anthony Bloom

Faculty Research, Scholarly, and Creative Activity

Carbon–climate (CC) feedbacks — arising from response of land and ocean carbon sinks to elevated CO2 and climate warming — are critical yet highly uncertain drivers of Earth’s climate trajectory. Processes such as permafrost thaw, tropical forest dieback, reduced ocean uptake, and intensifying climate extremes are already weakening natural carbon sinks, with potential to amplify warming and accelerate crossing of tipping points. Detecting and quantifying these dynamics requires sustained, high-resolution, spatially-comprehensive Earth Observations. Drawing on outcomes from a 2024 community workshop, we identify three core priorities for advancing CC feedback monitoring: (1) frequent, long-term measurements of carbon fluxes and stocks …

Personal Cultural Memory As Part Of Life Stories: Insights From Biographical Research On Japanese Canadian And Japanese American Wartime Experiences, Maria Wacławik

The Qualitative Report

The study focuses on the experiences of these communities during World War II, when they were displaced and incarcerated following the attack on Pearl Harbor. In the face of such traumatic events, the challenge arises in how individuals convey memories when words alone may not suffice. The main objective of this research was to determine, based on autobiographical narratives, the links between the memory of wartime experiences of Japanese Americans and Japanese Canadians and their ethnic identity. I do not analyze entire collections of mediated memories stored by narrators, but only those that were introduced during the interview as part …

Participatory, Project-Based Approach To Migrant Employment Research: Engaging Entrepreneurs Through Social Innovation, Sabina Kubiciel-Lodzińska, Jolanta Maj

The Qualitative Report

Qualitative research with entrepreneurs employing migrant workers poses significant challenges, particularly in recruiting respondents willing to discuss sensitive topics. This study explores an innovative method to overcome these barriers by engaging entrepreneurs through community-centered social initiatives. Specifically, we examine the "Opole Friendly Company for Migrants" project, a socially innovative competition conducted in the Opolskie Voivodeship from 2020 to 2024. The competition had two main goals. Firstly, it was aimed to foster participation in qualitative research by integrating respondents into a broader, socially meaningful context. The second goal was fostering community integration. The competition highlighted the role of entrepreneurs in supporting …

Parental And Staff Experiences Of Participation In The Report-Bpd Feasibility Study: Insights From An Embedded Qualitative Research, Wisam Muhsen, Ana Guillot-Lozano, Jos M. Latour

School of Nursing and Midwifery

Highlights: What are the main findings? Parents exhibited a clear understanding of the study’s aims and procedures and expressed confidence in its safety, whereas healthcare professionals displayed inconsistent awareness. Both parents and staff valued participation, highlighted emotional and logistical challenges in the neonatal unit environment, and offered practical suggestions to improve future neonatal research engagement. What are the implications of the main findings? Sustained, multi-directional communication is essential to maintain staff engagement and ensure consistent understanding across all research stakeholders. Embedding family-centred, emotionally supportive strategies—such as structured reflective tools and timely feedback—can enhance ethical recruitment, retention, and data quality in …

Additive Effects Of N-Acetylcysteine And [R4W4] Combination Treatment On Mycobacterium Avium, Kayvan Sasaninia, Iffat Hasnin Era, Nezam Newman, Jesse Melendez, Wajiha Akif, Eashan Sharma, Omid Nikjeh, Ira Glassman, Cristián Jiménez, Navya Sharma, Ama Xu, Maria Lambros, Miou Zhou, Rakesh Tiwari, Vishwanath Venketaraman

Pharmacy Faculty Articles and Research

Mycobacterium avium is an opportunistic pathogen and a leading contributor to nontuberculous mycobacterial infections in immunocompromised individuals. However, treatment duration, antibiotic toxicity, and resistance present challenges in the management of mycobacterium infections, prompting the need for novel treatment. N-acetylcysteine (NAC) has demonstrated potent antimycobacterial activity, while antimicrobial peptides such as the cyclic [R₄W₄] have shown additive effects when combined with first-line antibiotics. This study aimed to investigate the mechanism and efficacy of NAC and [R₄W₄] combination therapy against M. avium. A membrane depolarization assay was used to evaluate the effects of …

Racial Disparities In Clonal Hematopoiesis And Their Impact On Hematologic Malignancies, Zijian Zhang, Chao Cheng

Faculty, Staff and Students Publications

Clonal hematopoiesis of indeterminate potential (CHIP) is a known risk factor for hematologic malignancies (HM), but its distribution and clinical implications across diverse ancestries remain poorly characterized. In this study, we investigated CHIP and its progression to HM in a large, racially diverse cohort from the All of Us Research Program, comprising 245,388 participants. We identified 10,446 CHIP driver mutations in 9,476 individuals. Our analysis revealed clear racial disparities in CHIP prevalence and mutational profiles: African American (AA) individuals had higher odds of CHIP and exhibited distinct mutation patterns compared to White American (WA) individuals. Consistent with prior studies, CHIP …

Compromised Pressure-Generating Capacity Of Diaphragmatic Muscle And Its Interaction With The Lower Rib Cage At High Lung Volume During Airway Occlusion, Aladin M Boriek, Noralis Rodriguez-Santiago, Sanghyun Kim, Aubri Ford, Shari Wynd, Rolf D Hubmayr

Faculty, Staff and Students Publications

The pressure generating capacity of the diaphragm is generally thought to be compromised at high lung volume either due to loss of curvature or loss of its membrane tension. At a state of hyperinflation during airway occlusion at total lung capacity, the diaphragmatic muscle is forced to contract from an initial shorter length, the zone of apposition narrows, insertional force on the chest wall is reduced and abdominal compliance falls. We hypothesize that these altered mechanical conditions at high lung volume lead to a loss of the pressure generating capacity that is mediated by excessive muscle shortening rather than loss …

Design Of Future Scholarly Communication, Michael J. Salvo, John T. Sherrill

Michigan Tech Publications

This experience report documents the evolving practices of scholarly communication in the age of artificial intelligence while publishing an open-access peer-reviewed book. Drawing on experiences from 2023–2025, it explores open-access, print-on-demand publishing, collaborative authorship, and ethical integration of AI tools in academic workflows. Anchored by our work with the WAC Clearinghouse, we highlight how infrastructure, metadata, and peer review shape practices of scholarly production and assessment. We frame literacy not as a fixed competency but as an evolving set of practices shaped by technologies and platforms. Through a mix of analysis, publishing, and reflective design, we argue that scholarly communication …

Teaching The Teachers: Increasing Science-Literacy Integration In K-6 Classrooms, Brittany E. Kiser

Faculty and Staff Publications & Presentations

This session explores the crucial role of integrating hands-on science content within elementary literacy. Presenters will share pre-service teacher work and insights; participants will engage in hands-on activities demonstrating effective science-literacy integration for K-6 classrooms.

Variables Affecting Extreme Poverty Of Agricultural Sector Households In Indonesia, Syafira Karunia Sari, Nucke Widowati Kusumo Projo

Jurnal Ekonomi dan Studi Pembangunan

This research aims to describe the characteristics of households and the variables that influence extreme poverty in agricultural sector households in Indonesia. This research used the Socio-Economic Survey 2022 with descriptive analysis and binary logistic regression. The results show that 20.78 percent of agricultural sector households are extremely poor. The characteristics of an extremely poor household are: the average number of household members is 5-6 people, the household head is male, the household head is of productive age, lives in a rural area, the maximum education level of the household member is a junior high school/equivalent, more than half of …

Three Generations Under One Roof?: A Study Of Interhousehold Transfers Among Sandwich Generation In Indonesia, Vianey Weda Rahesti, I Dewa Gede Karma Wisana

Jurnal Ekonomi dan Studi Pembangunan

Empirical studies show some negative effects that arise in sandwich generation households. Even the negative impact of the sandwich generation raises the behavior that they want to leave the house. However, the empirical studies only measure sandwich generation if the parents live in the households, so it is necessary to recalculate sandwich generation households in Indonesia through an interhousehold transfer mechanism. This study examines interhousehold transfer differences among sandwich-generation households between parents, siblings, and others in Indonesia. Using the Indonesian Family Life Survey (IFLS) 2014, this study found that 4.539 or 28,6 percent of households are classified as the sandwich …

Money Demand Stability With Endogenous Structural Breaks And The Role Of Payment System Innovation In Indonesia, Wishnu Badrawani

Jurnal Ekonomi dan Studi Pembangunan

This study examines the stability of the demand for money function in Indonesia using quarterly data from 2007 to 2021, employing Gregory-Hansen's (1996) cointegration test and Hendry's general-to-specific approaches. The cointegration and error correction models show a causal relationship between money demand and its conventional determinants and payment system innovation. Considering the central bank policy that part of economic reforms captured by the structural break in the cointegration test and the stability test results of the short-run analysis, we confirm the stable narrow money and currency demand and its dynamics in Indonesia. The Gregory and Hansen test found a cointegrating …

The Impact Of Corruption And Fiscal Policy On Economic Growth In Asean Countries, Rizki Apriani, Abdul Bashir, Muhammad Subardin

Jurnal Ekonomi dan Studi Pembangunan

This study investigates the impact of government spending, the interaction between corruption and fiscal levels, government debt, and foreign direct investment on economic growth in seven ASEAN countries. Using the World Development Indicators database in the form of time series from the World Bank and the Asian Development Bank for 2000-2021. The approach used is panel data regression using a fixed effect model. The findings show that government spending and foreign direct investment have positive and significant contributions to the economic growth of seven ASEAN countries. There is strong evidence that the interaction between fiscal levels and corruption can distort …

Determinants Of Partnership In Micro And Small-Scale Manufacturing Firm, Janaska Nurrachmat

Jurnal Ekonomi dan Studi Pembangunan

This study aims to analyze the determinants of micro and small firms to conduct a partnership with other institutions. Using logit and probit this research estimates which factors that increase or decrease the probability of forming a partnership among micro and small firms. This study uses the data from the Indonesian Statistics Bureau to obtain detailed aspects from each micro and small business, this study also attempts to link the characteristics of larger firms within the same industry group that might influence forming a partnership among smaller firms. The result of this study shows that factors which have a strong …

Bank Indonesia's Behavior In Response To The Fed’S Policy, Kiky Indah Sari, Telisa Aulia Falianty

Jurnal Ekonomi dan Studi Pembangunan

Global economic instability is a challenge for the domestic economy, especially for emerging countries. A higher Federal Funds Rate for a longer period affects economic stability. Bank Indonesia plays a role in determining the BI rate to achieve economic goals. Indonesia, as an open economy, needs to consider external aspects in determining monetary policy. The Augmented Taylor Rule framework can facilitate this need to know about the determination of the BI rate. This study aims to identify the behavior of Bank Indonesia in response to the Fed's policy and the phenomenon of higher for longer. The research period was conducted …

The Role Of Tourism Sector On Central Java Economy, Sotya Fevriera, Agatta Shelly Septya Agni

Jurnal Ekonomi dan Studi Pembangunan

The purpose of this research is to analyze the effect of the tourism sector on the economy of Central Java province. The analysis method is a random effect model (REM), which is estimated using data from 35 regencies/cities in Central Java during some periods between 2001 and 2023. The result shows that the number of tourists, the number of tourism objects, the number of lodgings, the number of restaurants, and the number of workers on the tourist object, each have a positive and significant effect on the real GRDP. Moreover, this research also found that there is a random effect …