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Articles 53791 - 53820 of 1738423
Full-Text Articles in Entire DC Network
Get Creative With New Classes From Artplay, Shannon Thomason
Get Creative With New Classes From Artplay, Shannon Thomason
Browse All News
No abstract provided.
Ai In Health Professions Education, Cindy Schmidt
Ai In Health Professions Education, Cindy Schmidt
Faculty and Staff Publications
No abstract provided.
Enhancing Wind Turbine Aerodynamics With Flow Controller: A Review, Oluwaseyi O. Alabi, Adewale R. Inaolaji, Monsuru O. Mufutau
Enhancing Wind Turbine Aerodynamics With Flow Controller: A Review, Oluwaseyi O. Alabi, Adewale R. Inaolaji, Monsuru O. Mufutau
Al-Bahir
Wind turbines are vital to global renewable energy strategies, yet their aerodynamic performance often falls short of optimal levels, limiting overall efficiency and increasing operational loads. Flow controllers, devices designed to manipulate airflow around turbine blades, have emerged as a promising means of enhancing power capture while mitigating fatigue and structural stresses. This review presents a comprehensive synthesis of current research on aerodynamic optimization using flow controllers, covering both conventional and emerging technologies such as vortex generators, Gurney flaps, microtabs, and plasma actuators. The review evaluates the aerodynamic principles behind these devices, their reported performance improvements in laboratory and field …
Salicylic Acid Heterocyclic Derivatives: Chemical Synthesis And Biological Activity, Rawaa Hefdi Zaooli, Marwa Abdulameer Mseer, Amneen Mohammed Alsayegh
Salicylic Acid Heterocyclic Derivatives: Chemical Synthesis And Biological Activity, Rawaa Hefdi Zaooli, Marwa Abdulameer Mseer, Amneen Mohammed Alsayegh
Al-Bahir
Before a drug can be widely used, it must go through a long development process, starting from the discovery of the active ingredient and continuing with tests to confirm its safety and effectiveness. In this study, new olsalazine derivatives were synthesized, containing a fused morpholine-3-one ring and two five-membered heterocyclic rings (thiadiazole and oxadiazole). Common and readily available materials, such as salicylic acid (to prepare 2-hydroxy-5-nitrobenzoic acid) and inexpensive catalysts, were used to synthesize compounds from the first, 5,5'-(diazene-1,2-diyl)bis(2-hydroxy-3-nitrobenzoic acid) (A1), to the seventh, 6,6'-(diazene-1,2-diyl)bis(N-(4-(5-amino-1,3,4-oxadiazol-2-yl)phenyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide) (A7).
Each compound was characterized by FT-IR and ¹H-NMR spectroscopy, along with physical properties such …
Structure-Based Repurposing Of Clinically Approved Compounds For Pde-5 Inhibition: Integrative Computational And Pharmacokinetic Evaluation, Albashir Tahir, Yasir Idris Saleh, Ibrahim Khaleel Muazu
Structure-Based Repurposing Of Clinically Approved Compounds For Pde-5 Inhibition: Integrative Computational And Pharmacokinetic Evaluation, Albashir Tahir, Yasir Idris Saleh, Ibrahim Khaleel Muazu
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Background: Phosphodiesterase-5 (PDE-5) regulates intracellular cyclic guanosine monophosphate (cGMP) levels, modulating vascular smooth muscle tone. Sildenafil, a well-established PDE-5 inhibitor, is effective for erectile dysfunction and pulmonary hypertension but causes dose-dependent adverse effects. Identifying alternative scaffolds with comparable efficacy and improved safety remains a pharmacological priority.
Methods: A ligand-based virtual screening of the DrugBank database was performed using sildenafil as a reference. Compounds exhibiting ≥60% structural and electrostatic similarity were docked into the PDE-5 catalytic domain (PDB ID: 2h42) using Glide XP in the Schrödinger Suite. Top-scoring ligands were assessed for physicochemical, pharmacokinetic (ADMET), and toxicity parameters using SwissADME and …
Design And Mechanistic Investigation Of Novel Metallodrugs: From Structure-Activity Relationships To Selective Cancer Cell Targeting, Samad Khaksar, Nosrat Behzadi, Hasan Zakeri Zakeri, Peyman Salahshour, Sara Abdolmaleki
Design And Mechanistic Investigation Of Novel Metallodrugs: From Structure-Activity Relationships To Selective Cancer Cell Targeting, Samad Khaksar, Nosrat Behzadi, Hasan Zakeri Zakeri, Peyman Salahshour, Sara Abdolmaleki
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
The relentless pursuit of alternatives to conventional platinum-based chemotherapeutics, hampered by severe side effects and drug resistance, defines a critical frontier in oncology drug discovery. This review consolidates and highlights the significance of our recent advances in designing novel metallodrugs based on pyridine-2,6-dicarboxylate derivatives coordinated with various metal ions (Ga(III), Ce(IV), Zn(II), Cu(II), Ni(II), Sr(II)). Through systematic synthesis and evaluation, we establish how strategic structural modifications dictate cytotoxicity, cellular uptake, and mechanistic pathways. Our comprehensive in vitro profiling across a panel of human cancer cell lines (including A431, SW480, BEL-7404) revealed potent anticancer activity, with IC50 values as low as …
Sphenocentrum Jollyanum: Pharmacological Insights Into A Neglected African Medicinal Plant, Albashir Tahir
Sphenocentrum Jollyanum: Pharmacological Insights Into A Neglected African Medicinal Plant, Albashir Tahir
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Sphenocentrum jollyanum Pierre (Menispermaceae) is a West African medicinal plant used traditionally for various ailments, including malaria, diabetes, and reproductive disorders. Despite its ethnobotanical significance, comprehensive scientific validation of its pharmacological properties remains limited. This review aims to provide a comprehensive overview of the plant’s ethnobotany, phytochemistry, and pharmacological activities, integrating traditional knowledge with modern scientific insights to guide future research. A comprehensive literature search was conducted in PubMed, ScienceDirect, Scopus, Google Scholar, and Web of Science, covering publications up to April 2025. Search terms included "Sphenocentrum jollyanum", "ethnobotanical use", "pharmacological effects", and related keywords. Relevant articles were screened, and …
Green Pharmaceutical Systems: Alpha-Tocopherol Encapsulation In Nanostructured Lipid Carriers Via Microwaves-Based Technique As Advanced Topical Drug Delivery Systems, Hayder Kadhim Drais, Mohammed A Albarki, Hayder Ridha-Salman, Ahmed Abbas Hussein, Ashraf Abbas Drais
Green Pharmaceutical Systems: Alpha-Tocopherol Encapsulation In Nanostructured Lipid Carriers Via Microwaves-Based Technique As Advanced Topical Drug Delivery Systems, Hayder Kadhim Drais, Mohammed A Albarki, Hayder Ridha-Salman, Ahmed Abbas Hussein, Ashraf Abbas Drais
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Alpha tocopherol (Vitamin E) is practically insoluble in water. It is important for skin health due to its many therapeutic actions, such as antioxidant, anti-inflammatory, and photoprotection. Therefore, the purpose of this study is to develop, prepare, and evaluate nanostructured lipid carriers (NLCs)-based hydrogels as a topical dosage form to improve stability and therapeutic activity of vitamin E. The microwave-based method prepared five lavender oil-based NLCs (LN1–LN5) formulations that were assessed thermodynamically and entered into characterization processes. Hydrogels formulations based on NLCs (LNG1–LNG5) were prepared and evaluated. All of the lavender oil-based NLC formulations (LN1–LN5) had suitable surface charge, a …
History And Prevention Of Foot-And-Mouth Disease Virus In Iraq: A Review, Ashwaq M. S. Al-Jbouri, Baraa Hamid Hadi, Saad Mardi Muhammad, Raoof J. A. Maaroof, Nada Khazal K. Hindi, Karrar Kamoona, Zainab Ayad, Rusul Ahmed Mohammed
History And Prevention Of Foot-And-Mouth Disease Virus In Iraq: A Review, Ashwaq M. S. Al-Jbouri, Baraa Hamid Hadi, Saad Mardi Muhammad, Raoof J. A. Maaroof, Nada Khazal K. Hindi, Karrar Kamoona, Zainab Ayad, Rusul Ahmed Mohammed
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Foot-and-mouth disease Virus (FMDV) is an extremely transmittable viral illness that affects cloven-hoofed faunae, such as cattle, goats, sheep, and pigs. This study aimed to demonstrate the history and prevention of foot-and-mouth disease (FMD) in Iraq. This virus poses a significant threat to the economy, necessitating strict measures to control and prevent its spread, particularly due to its high morbidity and mortality rates, especially in young faunae. It is one of the most contagious diseases as it is transmitted directly or indirectly from a diseased fauna to a healthy one through contact with resources contaminated with the virus, such as …
From Dreamberries Swirling In My Tongue, Michael Balili
From Dreamberries Swirling In My Tongue, Michael Balili
Kritika Kultura
No abstract provided.
Full Issue, Kritika Kultura
Three Poems, Allan Justo Pastrana
Bagong Dating, Efmer E. Agustin
Bella Ciao, Lance Romulus S. Dayrit
Bella Ciao, Máno Dela Cruz
Metamorfascis, Arbeen R. Acuña
Panghian Festival, Benjo Gutierrez
Willie “I’M Just A Ceo” Cruz Meta, Doomscrolling, And Social Marketing Solutions And Social Marketing Solutions, Lawrence Bernabe
Willie “I’M Just A Ceo” Cruz Meta, Doomscrolling, And Social Marketing Solutions And Social Marketing Solutions, Lawrence Bernabe
Kritika Kultura
No abstract provided.
The Investigation, Eric Abalajon
Saranghae, Monina Morales!, Kaisa Aquino
Practical Applications And Theoretical Possibilities On The Study Of Kapres Of The Sociedad Científica, Christian Jil Benitez
Practical Applications And Theoretical Possibilities On The Study Of Kapres Of The Sociedad Científica, Christian Jil Benitez
Kritika Kultura
No abstract provided.
Mga Praktikal Na Aplikasyon At Teoretikal Na Landasin Ng Mga Pag-Aaral Sa Kapre Ng Sociedad Cientifica, Alvin Yapan
Mga Praktikal Na Aplikasyon At Teoretikal Na Landasin Ng Mga Pag-Aaral Sa Kapre Ng Sociedad Cientifica, Alvin Yapan
Kritika Kultura
No abstract provided.
The Kataw, Aidan Bernales
Toward Somewhere Livable: Contemporary Filipino Fiction Against Primers Of Values, Edgar Calabia Samar
Toward Somewhere Livable: Contemporary Filipino Fiction Against Primers Of Values, Edgar Calabia Samar
Kritika Kultura
This introduction to the Kritika Kultura special issue positions contemporary Filipino fiction as a counter-practice to state-driven moral discourses that flatten history, depoliticize crisis, and naturalize inequity. Reading against the NCCA’s Filipino Values for the Common Good, the essay argues that literary work in Filipino refuses the primer’s rhetoric of timeless virtues by foregrounding structural violence, decolonial epistemologies, and the uneven terrains of translation. Through close attention to the nine selected works written originally in Filipino— and to the English translations that accompany them—the introduction shows how fiction enacts a literacy of refusal that interrupts the coercive demands of state, …
In The Trenches: The Value Of Value In Contemporary Philippine Fiction, Glenn Diaz
In The Trenches: The Value Of Value In Contemporary Philippine Fiction, Glenn Diaz
Kritika Kultura
In this critical introduction, I investigate the possibilities in as well as the potential limits of the notion of “halaga” or value in thinking about the works that are part of this Kritika Kultura special literary section on contemporary Philippine fiction. I argue that the value of value as a critical paradigm is simultaneously formal, political, thematic, and practical, as much an aesthetic curiosity as it is a discursive dilemma, and that any inquiry into what is valued in Philippine fiction today necessarily inquires into how one lives at a fraught historical moment marked by persistent structural violence. I situate …
Red Flag In The Pearl Of The Orient?: The Image Of China In The Philippine Periodical La Solidaridad (1889-1895), Lois Mauri Anne Liwanag, Tiffany Ritz Mendoza, Sophia Marie Enriquez, Vianca Jamyla Joven, Leslie Anne Liwanag, Michael Charleston "Xiao" Chua
Red Flag In The Pearl Of The Orient?: The Image Of China In The Philippine Periodical La Solidaridad (1889-1895), Lois Mauri Anne Liwanag, Tiffany Ritz Mendoza, Sophia Marie Enriquez, Vianca Jamyla Joven, Leslie Anne Liwanag, Michael Charleston "Xiao" Chua
Kritika Kultura
This paper attempts to deduce how certain articles in La Solidaridad that specifically discussed China present a general image of the said Celestial Empire. Its significance lies in the fact that it can provide further knowledge of how Filipino intellectuals of that time perceive the Philippines in relation to its neighbors in Asia as well as the dynamics of the region’s political situation. This article is also important due to its potential to provide a Filipino perception of China before it was altered by the Philippine-Chinese territorial conflict that emerged during the latter part of twentieth century. This paper has …
Symbolism In Liu Yichang’S Inside The Temple, Lingshuang Lai, Yue Zhang
Symbolism In Liu Yichang’S Inside The Temple, Lingshuang Lai, Yue Zhang
Kritika Kultura
Liu Yichang’s (刘以鬯, 1918–2018) novella Inside the Temple (Sinei; 寺内), has been widely regarded, along with The Drunkard (Jiutu; 酒徒) and Intersection (Duidao; 对倒), as one of the best representatives of Liu’s work due to its narrative completeness and unique literary style. This article explores the symbols that Liu adopts in Sinei as he merges Western stream-of-consciousness techniques with Chinese poetic language. Liu’s synthesis offers fresh insight into humanity, life, and society from two perspectives: “abstract” and “concrete.” Certain images in the novella carry an “abstract” geometric quality and can be categorized as either symbols of the “straight line” (zhixian; …
Towards A Trans-Ethnic Representation Of Survival: Illness And Medical Writing In The Rag Doll Plagues, Qianqian Xu, Baojie Li
Towards A Trans-Ethnic Representation Of Survival: Illness And Medical Writing In The Rag Doll Plagues, Qianqian Xu, Baojie Li
Kritika Kultura
As a peculiar condition affecting the body or mind, illness is an inescapable aspect of human existence. While intimately connected to the body, it does not belong solely to the domain of natural science. Instead, illness is a phenomenon inherently embedded in power relations and cannot be understood without the influence of external factors such as politics, religion, ideology, and economics. In Alejandro Morales’s historical novel The Rag Doll Plagues, the diachronic histories of different geographic spaces intersect synchronically due to the pervasive presence of human disease. Morales invites readers to explore the interplay between illness— particularly epidemic and pandemic …
Korean Division Trauma And Mourning Communities, Kim Seok, Kim Jong Gon
Korean Division Trauma And Mourning Communities, Kim Seok, Kim Jong Gon
Kritika Kultura
Division trauma is marked by traits specific to the Korean context, including extreme ideological polarization and a complex mix of superiority and inferiority. Our research introduces the concept of “mourning communities” as a framework for collective healing. It synthesizes the psychoanalytic theory of mourning with Turner’s notion of Communitas, understood here as an evolving mode of social engagement. While previous studies have attributed division trauma to the collapse of the “Nation≠State” caused by colonial rule and the Korean War, they have not fully accounted for its enduring impact on Korean society. We argue that division trauma was internalized within the …
Whose Story Is It? Postcolonial Racialization, Social (Im)Mobility, And Crony Capitalism In Tash Aw’S Five Star Billionaire, Chi Miao
Kritika Kultura
Malaysian Chinese author Tash Aw’s novel Five Star Billionaire narrates the stories of five Malaysian Chinese individuals striving to establish themselves in Shanghai by seeking opportunities for advancement, economic prosperity, and personal transformation. Drawing from Dan Shen’s narratological theory of dual narrative dynamics, which states how texts can have overt and covert narrative progressions, this article elucidates the novel’s hidden agenda by exploring how the characters’ experiences in contemporary China are intricately connected to their past in Malaysia. If interpreted according to the narrative’s overt progression, Five Star Billionaire depicts individuals who are enticed and ensnared by the forces of …