Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 32881 - 32910 of 1738481

Full-Text Articles in Entire DC Network

When Customers Collide Online: The Hidden Power Of Approval In Digital Service Failures, Wei Wei, Lu Zhang, Bobbie Rathjens, Sean Mcginley Mar 2026

When Customers Collide Online: The Hidden Power Of Approval In Digital Service Failures, Wei Wei, Lu Zhang, Bobbie Rathjens, Sean Mcginley

Rosen Research Review

The research by Wei, Zhang, Rathjens, and McGinley reveals a surprising twist in how restaurant customers respond to online interactions after a service failure. When fellow customers chime in—either with support or mockery—their comments can dramatically shape how the original complainant feels, engages, and judges fairness. But the real game-changer? Whether the customer craves approval. Those with low need for approval react strongly to the tone of others’ comments, while high-approval seekers remain emotionally steady. This study uncovers the psychological undercurrents of electronic customerto- customer interaction (eCCI), offering fresh insights into empathy, justice, and digital engagement in hospitality.

Go to article

Putting Humanity First In Service Robotics: For Me, Robotics Is About Giving Hospitality Teams The Breathing Room To Care More Deeply For People., Manuel Rivera, Cynthia Mejia Mar 2026

Putting Humanity First In Service Robotics: For Me, Robotics Is About Giving Hospitality Teams The Breathing Room To Care More Deeply For People., Manuel Rivera, Cynthia Mejia

Rosen Research Review

In an engaging conversation with Juan Higueros, Co-Founder and COO of Bear Robotics, we explore his vision for human-centered robotics and how technology can empower hospitality teams to deliver deeper, more meaningful guest experiences.

Go to article

Sky-High Expectations: How Drones And Emotions Are Reshaping Food Delivery In Africa, Frank Badu-Baiden, Weisheng Chiu, Eudora Hagan, Victor Anderson Hodibert Mar 2026

Sky-High Expectations: How Drones And Emotions Are Reshaping Food Delivery In Africa, Frank Badu-Baiden, Weisheng Chiu, Eudora Hagan, Victor Anderson Hodibert

Rosen Research Review

The research by Badu-Baiden, Chiu, Hagan, and Hodibert unpacks the emotional, social, and psychological puzzle behind consumer acceptance of drone food delivery in Ghana. Using complexity theory and fsQCA, the study shows multiple adoption paths. Motivation, emotion, perceived risk, and social influence shape intention and willingness to pay. Positive emotions and usefulness drive interest, while privacy concerns and negative feelings hinder it. Trust and cultural context matter deeply.

Go to article

Boarding By Biometrics: How Smart Technology Is Reshaping Passenger Experience, Xiaoting Chi, Frank Badu-Baiden, Seongseop (Sam) Kim, Junwei Cao, Elena-Nicoleta Untaru, Heekyoung Jung, Heesup Han Mar 2026

Boarding By Biometrics: How Smart Technology Is Reshaping Passenger Experience, Xiaoting Chi, Frank Badu-Baiden, Seongseop (Sam) Kim, Junwei Cao, Elena-Nicoleta Untaru, Heekyoung Jung, Heesup Han

Rosen Research Review

The research by Chi, Badu-Baiden, Kim, Cao, Untaru, Jung, and Han explores how biometric boarding transforms airline travel. Using technology acceptance, agenda setting, and behavioral reasoning theories, the study reveals how ease of use, usefulness, media exposure, and attitudes shape adoption. Findings stress convenience, engagement, and targeted communication, with age and gender influencing responses. For airport managers and designers, the research offers practical strategies for secure, efficient, and passenger-centered boarding systems.

Go to article

The Pleasure Principle: Why Enjoyment May Be The Missing Link In Ai Adoption, Arthur Huang, Ahmet Bulent Ozturk, Tingting Zhang, Efren De La Mora Velasco, Adam Haney Mar 2026

The Pleasure Principle: Why Enjoyment May Be The Missing Link In Ai Adoption, Arthur Huang, Ahmet Bulent Ozturk, Tingting Zhang, Efren De La Mora Velasco, Adam Haney

Rosen Research Review

The research by Huang, Ozturk, Zhang, de la Mora Velasco, and Haney reveals a compelling insight: enjoyment—not just efficiency—is a key driver of whether guests will continue using AI in hospitality and tourism. By expanding the expectation-confirmation model, the study shows that perceived enjoyment, alongside performance and satisfaction, plays a pivotal role in shaping future use intentions. This shift toward hedonic value reframes how hoteliers and tourism professionals should design and promote AI services. The findings suggest that delight, fun, and emotional resonance are just as important as functionality when it comes to long-term engagement with AI-powered experiences.

Go to article

"Deep Down Here By The Dark Water Lived Old Gollum": The 1927 Public Opening Of The Wookey Hole Show Caves And 'The Hobbit', Kristine Larsen Mar 2026

"Deep Down Here By The Dark Water Lived Old Gollum": The 1927 Public Opening Of The Wookey Hole Show Caves And 'The Hobbit', Kristine Larsen

Journal of Tolkien Research

One central scene in The Hobbit – in which Bilbo Baggins finds the One Ring – takes place in a large subterranean cavern featuring a small island set within a body of water and reachable by boat. While this fictional location bears little resemblance to the caves of Cheddar Gorge, it closely parallels a series of caverns at Wookey Hole, located seven miles by road from Cheddar Gorge, that were opened up as public show caves in 1927. Now designated a Site of Special Scientific Interest (SSSI), Wookey Hole was already well-known in the 1920s for its unique geology, ancient …

Go to article

Educating For Responsible Ai Governance - Building Interdisciplinary Frameworks For The Management Of Artificial Intelligence, Grace Eboh Mar 2026

Educating For Responsible Ai Governance - Building Interdisciplinary Frameworks For The Management Of Artificial Intelligence, Grace Eboh

Southwestern Business Administration Journal

As Artificial Intelligence (AI) becomes increasingly prevalent across industries, there is a critical need for educational programs that teach effective AI governance and management. This article examines how educational institutions can develop comprehensive curricula to prepare professionals for the complex challenges of overseeing AI systems responsibly. It analyzes current gaps in AI governance education, proposes frameworks for curriculum design, and identifies key competencies required for effective AI stewardship. The findings suggest that successful AI governance education must adopt an interdisciplinary approach that integrates technical literacy, policy understanding, ethical reasoning, and organizational management.

Go to article

Utilizing The Financial Calculator For Graduated Annuities: Compound Rate, Discount Rate, Present Value, And Future Value, Su-Jane Chen Mar 2026

Utilizing The Financial Calculator For Graduated Annuities: Compound Rate, Discount Rate, Present Value, And Future Value, Su-Jane Chen

Southwestern Business Administration Journal

This paper lays out a comprehensive, systemic, and conceptual framework for applying a financial calculator to handle graduated (growing) annuities, a practically important topic that has not received its due attention in finance textbooks. It introduces an alternative to the conventional approach in transforming the growth rate and the interest rate into a single rate as I in the calculator. It then shows that both approaches give the same answer and demonstrates how they can be used interchangeably with the illustration of several numerical examples. In short, this article provides a thorough rationale and gives a clear presentation for the …

Go to article

Sustainable Cement-Blast Furnace Slag Mortar, Richa Jain, Harshit Jain, Ashish Nim Mar 2026

Sustainable Cement-Blast Furnace Slag Mortar, Richa Jain, Harshit Jain, Ashish Nim

Journal of Sustainable Construction Materials and Technologies

New building materials that required and produced less energy are need of today's infrastructure development. The ability of such building materials to promote sustainable development always puts its demand in active mode. With huge consumption of naturally occurring materials in building construction, the problem related to environment degradation is now common for world. Along with this, world is also facing the problem of reuse, recover and scientifically approved disposal of non-biodegradable wastes. Blast furnace slag (BFS) is one of those steel industry wastes that are abundantly available and their disposal arises as prime challenge for industries. This research work makes …

Go to article

Deep Learning Based Routing And Clustering Approaches For Energy Optimization In 5g Wireless Sensor Networks: A Review, Ghufraan Ali Mohammad Jawad, Ahmed M. Al-Salih Mar 2026

Deep Learning Based Routing And Clustering Approaches For Energy Optimization In 5g Wireless Sensor Networks: A Review, Ghufraan Ali Mohammad Jawad, Ahmed M. Al-Salih

Journal of Intelligent Informatics, Networking, and Cybersecurity

Next-generation Wireless Sensor Networks (WSNs), including 5G and Beyond-5G networks, have made significant progress. However, their development requires re-evaluating intelligent communication approaches to meet the growing demands for higher data transmission rates, more efficient spectral utilization, and reduced energy consumption. Scalability issues related to energy efficiency remain a critical concern for WSNs, which remain integral to the digital revolution. This paper investigates the role of Deep Learning (DL) methods in improving energy efficiency for routing and clustering in 5G WSNs. It is pertinent to note that Deep Q-Networks (DQNs) and their variants have significantly enhanced Cluster Heads (CHs) selection schemes …

Go to article

Modeling And Optimization Of Ppsu/Cu-Bdc Mmms And Ppsu/Cooh-Mwcnt@Cu-Bdc Mmms For Enhanced Water Treatment Performance, Ghaidaa M. Jaid, Adnan A. Abdulrazak, Sunarti Abdul Rahman, Muayad Al-Shaeli, Vahid Vatanpour, Qusay F. Alsalhy Mar 2026

Modeling And Optimization Of Ppsu/Cu-Bdc Mmms And Ppsu/Cooh-Mwcnt@Cu-Bdc Mmms For Enhanced Water Treatment Performance, Ghaidaa M. Jaid, Adnan A. Abdulrazak, Sunarti Abdul Rahman, Muayad Al-Shaeli, Vahid Vatanpour, Qusay F. Alsalhy

Engineering and Technology Journal

Water quality is increasingly of concern today due to industrial wastewater that contains heavy metals, particularly lead (Pb2+). What follows is a study aiming at adjusting operational variables affecting the performance of two types of mixed-matrix membranes (MMMs) used for lead ion removal from simulated wastewater. The first employs polymer polyphenylsulfone (PPSU) by embedding copper-organic frameworks (Cu-BDC), and the second MMMs incorporate a novel COOH-MWCNT@Cu-BDC nanocomposite in the same polymer. MOF nanoparticles were added to the matrix to improve membrane performance, hydrophilicity, contact angle, porosity, and fouling resistance. Three operating parameters were modeled and optimized for their influence …

Go to article

Bilateral Lower Palpebral Conjunctival Protrusion In A Patient With Traumatic Unilateral Carotid-Cavernous Fistula, Sharfuddin M. Chowdhury, Omar A. Ababtain Mar 2026

Bilateral Lower Palpebral Conjunctival Protrusion In A Patient With Traumatic Unilateral Carotid-Cavernous Fistula, Sharfuddin M. Chowdhury, Omar A. Ababtain

Saudi Medical Journal

No abstract provided.

Go to article

Chronic Total Occlusion Percutaneous Coronary Intervention: A Consensus Of The National Heart Center In Collaboration With The Saudi Cto Club Of The Saudi Arabian Cardiac Interventional Society, Waqar H. Ahmed, Khalid Aljohani, Sultan Alotaibi, Motasem Alyamani, Mohammed Almohammadi, Ahmed Alhamami, Hani Abdelhadi, Owayed Alshammeri, Abdullah Alsaiedi, Abdulrahman Almoghairi, Abdulrahman Qahtani, Saleh Khouj, Shatha Alalawi, Walid Alharbi Mar 2026

Chronic Total Occlusion Percutaneous Coronary Intervention: A Consensus Of The National Heart Center In Collaboration With The Saudi Cto Club Of The Saudi Arabian Cardiac Interventional Society, Waqar H. Ahmed, Khalid Aljohani, Sultan Alotaibi, Motasem Alyamani, Mohammed Almohammadi, Ahmed Alhamami, Hani Abdelhadi, Owayed Alshammeri, Abdullah Alsaiedi, Abdulrahman Almoghairi, Abdulrahman Qahtani, Saleh Khouj, Shatha Alalawi, Walid Alharbi

Saudi Medical Journal

Objective: Chronic total occlusion (CTO) is one of the most complex and technically demanding percutaneous coronary interventions (PCI). Over the last two decades, technological and procedural advancements have significantly improved clinical outcomes. However, CTO-PCI practice and outcomes remain suboptimal with a lack of standardized approaches. Methods: The Saudi CTO Club has been actively working to enhance collaboration among CTO operators throughout the region. The National Heart Center (NHC), in collaboration with the Saudi Arabian Cardiac Interventional Society (SACIS), convened national experts to develop a consensus document and workflow for integrating CTO-PCI into clinical practice in Saudi Arabia. This consensus document …

Go to article

Epidemiological Mapping Of Drug-Susceptible And Resistant Tuberculosis In 30 Who High-Burden Countries: Three Decades Of Gbd 2023 Trends, Projections To 2043 And Concordance With Who Estimates, Azfar A. Ishaqui, Salman A. Ahmad, Shoaib Alam, Narendar Kumar, Javeria Farooq, Khalid Orayj, Rabbiya Ahmad, Mohammed Zawiah, Mustapha Mohammed, Muhammad Imran, Asaad A. Asaad Khalil, Mohammed A. Kaddoura, Sultan M. Alshahrani, Adnan Iqbal, Muhammad B. Maqsood Mar 2026

Epidemiological Mapping Of Drug-Susceptible And Resistant Tuberculosis In 30 Who High-Burden Countries: Three Decades Of Gbd 2023 Trends, Projections To 2043 And Concordance With Who Estimates, Azfar A. Ishaqui, Salman A. Ahmad, Shoaib Alam, Narendar Kumar, Javeria Farooq, Khalid Orayj, Rabbiya Ahmad, Mohammed Zawiah, Mustapha Mohammed, Muhammad Imran, Asaad A. Asaad Khalil, Mohammed A. Kaddoura, Sultan M. Alshahrani, Adnan Iqbal, Muhammad B. Maqsood

Saudi Medical Journal

Objectives: Tuberculosis (TB) continues to drive infectious mortality worldwide. The study characterized the evolution of drug-susceptible TB (DS-TB), multidrug-resistant TB (MDR-TB), and extensively drug-resistant TB (XDR-TB) in 30 WHO high-burden countries, linking current patterns to long-term trends, age structure, and forward-looking scenarios to 2043. Methods: Using GBD 2023 estimates for 1990–2023, we extracted incidence, mortality, and DALYs as age-standardized rates (ASR) per 100,000 with 95% uncertainty intervals. Temporal dynamics were summarized with Estimated Annual Percent Change (EAPC) and extended linearly to 2043. GBD incidence and mortality were compared against WHO national TB series for 2010–2023. Results: Overall TB incidence ASR …

Go to article

The Application Effect Of Modified Pressure-Reducing Fixation Protective Nasal Strip In The Nursing Care Of Patients Receiving High-Flow Nasal Cannula Therapy, Ying Zhou, Xuting He, Jianying Sang Mar 2026

The Application Effect Of Modified Pressure-Reducing Fixation Protective Nasal Strip In The Nursing Care Of Patients Receiving High-Flow Nasal Cannula Therapy, Ying Zhou, Xuting He, Jianying Sang

Saudi Medical Journal

Objective: To evaluate the efficacy of a modified pressure-reducing fixation protective nasal strip in preventing device-related pressure injuries and improving nursing outcomes in patients undergoing high-flow nasal cannula (HFNC) therapy. Methods: This study included 60 patients receiving HFNC therapy from January 2024 to September 2024. Participants were randomly divided into an observation group (n = 30), which used the modified decompression fixation protective nasal strip, and a control group (n = 30), which underwent standard care with hydrocolloid dressing protection. The study compared general demographic data, the interval between fixation strap changes, frequency of catheter position adjustments, skin management effectiveness …

Go to article

Validity And Reliability Of The Arabic Voice Activity And Participation Profile (A-Vapp) Questionnaire, Nawaf S. Alqarni, Hamad F. Alrabiah, Nasser F. Alsunbul, Manal A. Bukhari, Mohamed Farahat, Mohammed Almohizea, Tamer A. Mesallam, Khalid H. Malki Mar 2026

Validity And Reliability Of The Arabic Voice Activity And Participation Profile (A-Vapp) Questionnaire, Nawaf S. Alqarni, Hamad F. Alrabiah, Nasser F. Alsunbul, Manal A. Bukhari, Mohamed Farahat, Mohammed Almohizea, Tamer A. Mesallam, Khalid H. Malki

Saudi Medical Journal

Objectives: The purpose of this study was to translate and validate the Voice Activity and Participation Profile (VAPP), a comprehensive tool for assessing the impact of voice disorders on daily life activities and social participation, into Arabic and to test its reliability among voice disorders patients in Riyadh, Saudi Arabia \looseness-1 Methods: A descriptive, questionnaire-based validation study was conducted at two university hospitals from December 2023 to September 2024. The VAPP was translated using forward and backward translation methods from English into Arabic. The questionnaire's reliability and internal consistency were assessed using Cronbach's alpha and test-retest reliability. To measure …

Go to article

Stratifying Renal Risk In End-Stage Renal Disease: Evidence From A Population-Based Dialysis Registry In Northern Saudi Arabia, Reem Eltayeb, Naif K Binsaleh, Ghaida A Alsaif, Mona Hm Ahmed, Ahmed M Taha, Abdelhameed Abdelzaher, Zinab Alatawi Mar 2026

Stratifying Renal Risk In End-Stage Renal Disease: Evidence From A Population-Based Dialysis Registry In Northern Saudi Arabia, Reem Eltayeb, Naif K Binsaleh, Ghaida A Alsaif, Mona Hm Ahmed, Ahmed M Taha, Abdelhameed Abdelzaher, Zinab Alatawi

Saudi Medical Journal

Objectives: We examined the relationship of age, gender, smoking, nationality, and place of residence with renal dysfunction severity in end-stage renal disease (ESRD) patients. Methods: We performed a cross-sectional study of ESRD registry data collected from King Khalid Hospital in Hail, Saudi Arabia. Adults (≥ 15 years) treated from March 2023 - February 2024 were enrolled. Serum creatinine and urinary albumin concentrations were measured (based on primary [≥ 625 μmol/L and ≥ 18 mg/L, respectively] and sensitivity thresholds). Bivariate analyses, interaction testing, sensitivity models, and multivariable logistic regression were employed. Results: Of 212 patients (50.9% male), based on primary thresholds, …

Go to article

Critically Ill Patients Presenting To The Emergency Department; Outcome Review In A Tertiary Care Center, Maan Jamjoom, Lina Sami Reda, Bsaim Abdulsalam Altirkistani, Samer Tariq Anwar Ahmed, Samer Ali Alasmari, Abdulrahman Adnan Almehmadi, Ahmad Loay Atiah, Faisal Abdulaziz Boker, Rand Ayman Maddah Mar 2026

Critically Ill Patients Presenting To The Emergency Department; Outcome Review In A Tertiary Care Center, Maan Jamjoom, Lina Sami Reda, Bsaim Abdulsalam Altirkistani, Samer Tariq Anwar Ahmed, Samer Ali Alasmari, Abdulrahman Adnan Almehmadi, Ahmad Loay Atiah, Faisal Abdulaziz Boker, Rand Ayman Maddah

Saudi Medical Journal

Objective: Critically ill patients presenting to the emergency department require prompt recognition and prioritized care due to the severity of their conditions. Reviewing their clinical outcomes helps guide future planning and resource allocation. This study aims to highlight the outcomes of patients triaged as CTAS I and II in the emergency department of a tertiary care center in Jeddah, Saudi Arabia. Methods: A single-center retrospective cohort study was conducted in the emergency department of a tertiary healthcare center, National Guard Health Affairs, in Jeddah. The study provides a comprehensive assessment of factors (including length of stay) and outcomes for a …

Go to article

Microbiological Profile And Antibiotic Resistance In Relation To Risk Of Recurrence And Fistula Following Perianal Abscess Drainage: A Retrospective Study, Saleh A. Busbait Mar 2026

Microbiological Profile And Antibiotic Resistance In Relation To Risk Of Recurrence And Fistula Following Perianal Abscess Drainage: A Retrospective Study, Saleh A. Busbait

Saudi Medical Journal

Objective: The practice of obtaining routine intraoperative cultures and administering postoperative antibiotics for perianal abscess treatment continues to be debated, so far, there is no established evidence linking these practices to improved patient outcomes. This study investigated the microbial distribution together with antibiotic resistance and their relationship to abscess recurrence or fistula development. Methods: The study analyzed 242 patients who received their first perianal abscess treatment through incision and drainage procedures at a Saudi Arabian tertiary center from 2019 to 2023. Swab cultures were obtained intraoperatively. A descriptive statistics, Chi-square tests and antibiotic resistance were analyzed. Results: The most frequently …

Go to article

An Investigation Of The Correlation Between Total Intracranial Volume And Body Mass Index, Walaa M. Alsharif, Fahad H. Alhazmi, Ali D. Almutairi, Rahaf M. Alharbi, Lana M. Alsaedi, Razan A. Alharbi, Amirah F. Alsaedi, Abdulaziz A. Qurashi, Adnan A. Alahmadi, Khalid M. Alshamrani, Faisal A. Alrehily, Shrooq T. Aldahery, Osamah M. Abdulaal, Reem M. Elkady Mar 2026

An Investigation Of The Correlation Between Total Intracranial Volume And Body Mass Index, Walaa M. Alsharif, Fahad H. Alhazmi, Ali D. Almutairi, Rahaf M. Alharbi, Lana M. Alsaedi, Razan A. Alharbi, Amirah F. Alsaedi, Abdulaziz A. Qurashi, Adnan A. Alahmadi, Khalid M. Alshamrani, Faisal A. Alrehily, Shrooq T. Aldahery, Osamah M. Abdulaal, Reem M. Elkady

Saudi Medical Journal

\looseness-1 Objective: Total intracranial volume (TICV) is an important covariate in brain volumetric analysis that can vary significantly between participants. This study aimed to investigate the association between body mass index (BMI) and TICV. Methods: 152 healthy volunteers were recruited. The BMI was calculated, and T1-weighted images were acquired to estimate brain volumetric values. The data were analyzed using volBrain software. Results: Male participants have significantly higher GM, WM, CSF, TICV, cerebellum GM, cortical GM, subcortical GM and cerebrum GM volumes compared to female. There were significant differences in GM, TICV, cerebellum GM, cortical GM, subcortical GM and cerebrum GM …

Go to article

A Comprehensive Analysis Of Overweight, Obesity, And Failure To Thrive In Pediatric Inpatients: Prevalence, Diagnostic Practices, And Management Approaches At A Tertiary Hospital In Riyadh, Saudi Arabia, Ibrahim A Al Alwan, Elaf A Alshammari, Ahmed A Alabdulkarim, Abdulaziz A Ajeebi, Afnan A Alhazimi, Nawaf A Alhamied, Deema Y Alasmari Mar 2026

A Comprehensive Analysis Of Overweight, Obesity, And Failure To Thrive In Pediatric Inpatients: Prevalence, Diagnostic Practices, And Management Approaches At A Tertiary Hospital In Riyadh, Saudi Arabia, Ibrahim A Al Alwan, Elaf A Alshammari, Ahmed A Alabdulkarim, Abdulaziz A Ajeebi, Afnan A Alhazimi, Nawaf A Alhamied, Deema Y Alasmari

Saudi Medical Journal

Objective: This study aimed to assess the prevalence, diagnostic accuracy, and inpatient management of pediatric weight abnormalities at a tertiary children's hospital in Riyadh, Saudi Arabia, using a retrospective cohort design. Methods: The study analyzed medical records of pediatric inpatients aged 2–14 years admitted to King Abdullah Specialized Children's Hospital (KASCH) in 2023. Data collected included anthropometrics, dietary history, physical activity, diagnostic workup, and treatment plans. Overweight and obesity were classified using BMI percentiles, while FTT was identified via weight-for-age and growth percentile criteria. Descriptive statistics were used to analyze diagnostic accuracy and factors influencing missed diagnoses. Results: Of 7,771 …

Go to article

Mapping Health Research Involving Human Subjects In Saudi Arabia: A Text Mining And Topic Modeling Analysis, Khalid A. Alhussain Mar 2026

Mapping Health Research Involving Human Subjects In Saudi Arabia: A Text Mining And Topic Modeling Analysis, Khalid A. Alhussain

Saudi Medical Journal

Objectives: To identify dominant and underrepresented research topics and to classify published studies by design and data sources in health research involving human subjects from Saudi Arabia. Methods: This retrospective study analyzed PubMed-indexed health articles related to Saudi Arabia from 1959 to March 2025. Text mining was used to identify studies conducted in the country involving human subjects. Eligible articles were classified by study design and data sources. Topic modeling using non-negative matrix factorization was applied to identify topics based on the primary research focus. Results: A total of 36,452 records of studies conducted in Saudi Arabia were initially identified. …

Go to article

Translational Barriers To Aav And Crispr Gene Therapy In Diabetes, Abdulrahman G. Alharbi Mar 2026

Translational Barriers To Aav And Crispr Gene Therapy In Diabetes, Abdulrahman G. Alharbi

Saudi Medical Journal

Gene therapy targets diabetes pathophysiology rather than symptoms, yet clinical translation is slower than preclinical success. This review synthesizes 143 registered trials (ClinicalTrials.gov, 2010-2025) identifying systematic implementation barriers. Despite >15 years of development, 83% of trials remain in Phase I-II. Only zimislecel achieved Phase III outcomes (83% insulin independence at 12 months, n=12, requiring immunosuppression). VM202 for diabetic neuropathy failed Phase III despite positive extension results. Three systematic barriers emerged: (1) human transduction efficiency is 6-8.7-fold lower than preclinical models; (2) pre-existing immunity excludes 58-78% of candidates; (3) manufacturing capacity serves <2.5% of target population (40-400 years to treat at maximum capacity). These constraints explain why ex vivo cell therapies advanced to efficacy trials while in vivo gene delivery remains in Phase I despite longer development timelines. Research priorities should emphasize non-viral delivery systems offering scalable manufacturing and universal hypoimmune donor cells to address access barriers.

Go to article

Semaglutide In Metabolic Medicine: A Review On Clinical Applications And Emerging Therapeutics, Abdulrahman A. Aljabri Mar 2026

Semaglutide In Metabolic Medicine: A Review On Clinical Applications And Emerging Therapeutics, Abdulrahman A. Aljabri

Saudi Medical Journal

Obesity and type 2 diabetes mellitus affect over 800 million and 537 million individuals worldwide. Semaglutide, a weekly glucagon-like peptide-1 receptor agonist, has advanced treatment of pathophysiological processes linked to metabolic dysregulation. This review consolidates evidence on its mechanisms of action, clinical effectiveness across established and emerging applications, safety, and prospects for personalized therapy. Clinical studies have shown that semaglutide sustains glycemic control, promotes substantial weight loss, and provides cardiovascular and renal protection. Recent FDA clearance marks the first therapeutic alternative for metabolic dysfunction-associated steatohepatitis among the emerging applications. Pharmacogenomic insights facilitate personalized therapy; however, clinical applications remain in experimental …

Go to article

Rehabilitation Outcomes Of Pediatric Burn Survivors In Saudi Arabia: A Thematic Narrative Review And Policy Implications, Abdulaziz Ghandurah, Mshari Alghadier Mar 2026

Rehabilitation Outcomes Of Pediatric Burn Survivors In Saudi Arabia: A Thematic Narrative Review And Policy Implications, Abdulaziz Ghandurah, Mshari Alghadier

Saudi Medical Journal

Pediatric burns in Saudi Arabia are predominantly household scalds in young children, causing long-term disability from scarring, contractures, pain/itch, psychosocial distress, and disrupted schooling. This thematic narrative review (2010–2025) synthesizes global and regional evidence, appraises outcome measures with attention to Arabic availability, and translates findings into Vision 2030–aligned policy actions. Evidence supports early, multidisciplinary care anchored in standardized outcome tracking. Pressure-garment therapy remains inconclusive, whereas virtual reality reduces procedural pain and telerehabilitation serves families distant from tertiary centers. A minimum national outcome set is proposed spanning scar quality (VSS, POSAS), joint range of motion, age-appropriate pain and itch scales (FLACC/FPS-R/NRS), …

Go to article

Understanding The Cost Consequences Of Pharmacist Roles In Managing Long-Term Illnesses: A Systematic Review, Muhammad Zahid Iqbal Mar 2026

Understanding The Cost Consequences Of Pharmacist Roles In Managing Long-Term Illnesses: A Systematic Review, Muhammad Zahid Iqbal

Saudi Medical Journal

Objective: This review looked at how different pharmacist-led services influence medication spending and other economic outcomes for people living with long-term illnesses. Methods: To gather the evidence, we followed the PRISMA 2020 approach and a comprehensive search was conducted using multiple sources, including Web of Science, ProQuest, Scopus, the Directory of Open Access Journals, ScienceDirect, PubMed, and Google Scholar. We included studies that examined pharmacist involvement in medication management such as MTM, medication reconciliation, deprescribing efforts, or full medication reviews and that reported some form of cost or economic outcome in chronic disease care. We left out non-English work, conference …

Go to article

Impact Of Clinical Pharmacist Educational Intervention On Lipid Profile And Its Clinical Outcomes, Saad Saeed Alqahtani Mar 2026

Impact Of Clinical Pharmacist Educational Intervention On Lipid Profile And Its Clinical Outcomes, Saad Saeed Alqahtani

Saudi Medical Journal

Objective: To assess how clinical pharmacist-led educational interventions affect lipid profile parameters and related clinical outcomes in cardiovascular disease-risk individuals. Methods: This systematic review completed as according to PRISMA 2020 principles. Searches were done on PubMed, ScienceDirect, ProQuest, Google Scholar, DOAJ, Scopus, and Web of Science. Studies examining impact of the pharmacists' educational initiatives on lipid levels were included. However, case reports, conference proceedings, and studies in other languages not in English, and studies lacking full-text access were excluded from the review. Following screening and eligibility assessment, a total of 33 papers were included out of the 1731 records found. …

Go to article

A Multi-Task Cnn-Lstm Model With Attention Mechanism For Climate Temperature Forecasting Over Iraq, Salim M. Mohammed, Omar M. Mustafa, Lailan M. Haji, Omar M. Ahmed Mar 2026

A Multi-Task Cnn-Lstm Model With Attention Mechanism For Climate Temperature Forecasting Over Iraq, Salim M. Mohammed, Omar M. Mustafa, Lailan M. Haji, Omar M. Ahmed

Al-Bahir

Accurate forecasting of climate temperature at the regional scale is crucial to agriculture planning, water resource management, and disaster preparedness. Still, due to the nonlinear and complicated temporal patterns in regions such as Iraq, conventional climate models fail to meet this imperative. This paper presents a novel deep learning model that not only predicts monthly average temperature values but also predicts the temperature trend, hence addressing the regional climate prediction problem holistically. The proposed model is designed as a multi-task deep learning framework integrating Convolutional Neural Networks, Long Short-Term Memory networks, and an attention mechanism to process historical monthly temperature …

Go to article

Health Effects Of Cadmium And Manganese Exposure On Luteinizing Hormone Levels: A Pilot Study Of Female Infertility, Shatha F. Alhous, Anees A. Al-Hamzawi, Murtadha Sh. Aswood Mar 2026

Health Effects Of Cadmium And Manganese Exposure On Luteinizing Hormone Levels: A Pilot Study Of Female Infertility, Shatha F. Alhous, Anees A. Al-Hamzawi, Murtadha Sh. Aswood

Al-Bahir

Female infertility occurs for many reasons, some unknown. Exposure to heavy metals is a risk factor that negatively impacts on female reproductive system. Therefore, this study aimed to evaluate the effect of cadmium Cd and manganese Mn on luteinizing hormone LH levels for females’ infertility. This study included a healthy group (n = 20), primary infertile females (n = 40), and secondary infertile females (n = 20) collected from Al-Zahraa hospital in Najaf center, Iraq. The Atomic Absorption Spectroscopy (AAS) was used to measure the cadmium and manganese concentrations and LH levels were measured by a Maglumi 800 from Snibe …

Go to article

Enhanced Cuckoo Search-Based Optimization For Single Distributed Generation Placement And Sizing In Radial Distribution Systems, Samson Oladayo Ayanlade, Abdulrasaq Jimoh, Richard Oladayo Olarewaju, Ignatius Kema Okakwu, Israel O. Adejumobi, Joseph B. Samson, Oluwadare A. Adebisi, Oluwadare O. Akinrogunde Mar 2026

Enhanced Cuckoo Search-Based Optimization For Single Distributed Generation Placement And Sizing In Radial Distribution Systems, Samson Oladayo Ayanlade, Abdulrasaq Jimoh, Richard Oladayo Olarewaju, Ignatius Kema Okakwu, Israel O. Adejumobi, Joseph B. Samson, Oluwadare A. Adebisi, Oluwadare O. Akinrogunde

Al-Bahir

This paper presents an Enhanced Cuckoo Search Algorithm (ECSA) to optimally place and size Distributed Generation (DG) in radial distribution systems to minimize real power loss within operating constraints. The proposed ECSA has exponentially decaying adaptive Lévy flights, constraint-aware solution repair with dynamic penalty coefficients, and diversity-directed stochastic replacement to enhance search robustness and convergence speed. It was tested with 30 independent runs on the IEEE 33-bus, IEEE 69-bus, and a practical Nigerian 32-bus distribution network. The simulations show that the ECSA lowers the active power loss of the IEEE 33-bus system from 201.58 kW to 102.75 kW (49.03%), and …

Go to article

First Prev Next Last