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Articles 31141 - 31170 of 1737590
Full-Text Articles in Entire DC Network
Digital Assessment Of Subtractive And Additive Cad/Cam Fabrication Methods On The Fit And Accuracy Of Lithium Disilicate Veneers, Sara Fikry Elshafei Dr, Islam Heiba Dr, Basma Fayyad, Maha Nagy
Digital Assessment Of Subtractive And Additive Cad/Cam Fabrication Methods On The Fit And Accuracy Of Lithium Disilicate Veneers, Sara Fikry Elshafei Dr, Islam Heiba Dr, Basma Fayyad, Maha Nagy
Dentistry
No abstract provided.
Prevalence Profile Perceived Stress And Impact On Quality Of Life For Recurrent Aphthous Ulcers: A Cross-Sectional Epidemiological Study In Egypt, Dalia Ghalwash
Dentistry
Recurrent Aphthous Ulcerations (RAU) are among the most frequent oral ulcers with unknown etiology and multiple risk factors. This study assessed the prevalence profile of aphthous ulcers, risk factors, levels of perceived stress, and their impact on quality of life in an Egyptian sample. This study involved screening 4100 individuals from the outpatient clinic, Faculty of Dentistry, The British University in Egypt, and several Egyptian governorates. Patients were subjected to clinical examination and patient interviews for accurate diagnosis and collection of data. The Perceived Stress Scale (PSS) was used to assess levels of perceived stress, and the Oral Health Impact …
Nigella Sativa Oil-Loaded Treated Dentin Matrix Hydrogel As An Alternative Biomaterial For Direct Pulp Capping: A Systematic Review, Alfin R. Cahyadi, Ayu Annafi, Malika Q. Rahmalia, Adelisa D. Ryani, Tania Saskianti, Harly Prabowo, Nadia Kartikasari, Abil Kurdi, Agus Dahlan
Nigella Sativa Oil-Loaded Treated Dentin Matrix Hydrogel As An Alternative Biomaterial For Direct Pulp Capping: A Systematic Review, Alfin R. Cahyadi, Ayu Annafi, Malika Q. Rahmalia, Adelisa D. Ryani, Tania Saskianti, Harly Prabowo, Nadia Kartikasari, Abil Kurdi, Agus Dahlan
Journal of Dentomaxillofacial Science
Objective: To assess evidence on Treated Dentin Matrix Hydrogel (TDMH) and Nigella sativa oil (NSO), individually or combined, as biomaterials for direct pulp capping (DPC) and their reparative dentin promotion ability. Methods: A systematic search of PubMed, EBSCO, ScienceDirect, and Wiley (January 1, 2018–December 31, 2023) was conducted using MeSH-based terms associated with ``treated dentin matrix hydrogel,'' ``Nigella sativa oil,'' and ``direct pulp capping.'' Eligible studies included in vitro, in vivo, and clinical research evaluating TDMH or NSO for DPC; studies with no outcome data were excluded. Risk-of-bias assessment was performed using ROB2 (clinical) and SYRCLE (animal). Because of …
Automated Classification Of Periodontal Bone Loss In Periapical Radiographs Using Convolutional Neural Networks, Ramadhan Hardani Putra, Eha Renwi Astuti, Alhidayati Asymal, Aga Satria Nurrachman, Afifah Salsabila, Nasywa Athaillah Safitri, Fatina Yasmin, Andrew Nalley
Automated Classification Of Periodontal Bone Loss In Periapical Radiographs Using Convolutional Neural Networks, Ramadhan Hardani Putra, Eha Renwi Astuti, Alhidayati Asymal, Aga Satria Nurrachman, Afifah Salsabila, Nasywa Athaillah Safitri, Fatina Yasmin, Andrew Nalley
Journal of Dentomaxillofacial Science
Objective: Periodontal diseases, including periodontitis, affected approximately 951.3 million people worldwide in 2021. Early detection and accurate diagnosis are crucial for determining effective treatment plans. Radiographic examination, particularly periapical radiographs, is a valuable method for assessing periodontal bone loss (PBL). However, classification of PBL stages is often influenced by observer subjectivity due to the complexity of manual measurement. This study aimed to develop and evaluate convolutional neural network (CNN) models for automated PBL classification in periapical radiographs.
Material and Methods: A dataset of 600 periapical radiographs was used, consisting of 480 training images, 60 validation images, and 60 testing images. …
Oral Health–Related Quality Of Life Following Complete Denture Rehabilitation In Diabetic Edentulous Patients: A 6-Month Prospective Study, Eri Hendra Jubhari, Edy Machmud, Mohammad Dharma Utama, Bahruddin Thalib, Stang Stang, Rifaat Nurrahma, Indah Tresnawati
Oral Health–Related Quality Of Life Following Complete Denture Rehabilitation In Diabetic Edentulous Patients: A 6-Month Prospective Study, Eri Hendra Jubhari, Edy Machmud, Mohammad Dharma Utama, Bahruddin Thalib, Stang Stang, Rifaat Nurrahma, Indah Tresnawati
Journal of Dentomaxillofacial Science
Objective: Edentulism and diabetes mellitus (DM) are associated with impaired oral function and diminished quality of life. Complete denture rehabilitation plays a pivotal role in the restoration of mastication, comfort, and self-confidence. This study aimed to examine changes in oral health–related quality of life (OHRQoL) after complete denture insertion in diabetic edentulous patients using the OHIP-14 and Geriatric Oral Health Assessment Index (GOHAI) questionnaires.
Materials and Methods: This prospective, longitudinal observational study included 25 completely edentulous diabetic patients. Their OHRQoL was evaluated at baseline and at 1, 2, and 6 months postdenture insertion using validated questionnaires, namely, OHIP-14 and GOHAI. …
Determinants Of Toothbrushing Behavior Among 12-Year-Old Children: An Application Of The Health Belief Model, Fitri D. Oktadewi, Riski A. Hidayah, Ryana B. Purnama, Ananda P. Yuliani
Determinants Of Toothbrushing Behavior Among 12-Year-Old Children: An Application Of The Health Belief Model, Fitri D. Oktadewi, Riski A. Hidayah, Ryana B. Purnama, Ananda P. Yuliani
Journal of Dentomaxillofacial Science
Objective: Effective toothbrushing behaviors in school-aged children play an important role in preventing dental and oral health problems. At the age of 12, the behaviors constitute a critical phase in the formation of healthy lifestyle habits. Therefore, this study aimed to analyze the factors that influence toothbrushing behaviors in 12-year-old children based on the Health Belief Model (HBM) theory.
Material and Methods: A total of 92 12-year-old children were selected by cluster sampling method at elementary schools in Banyumas, Central Java. The independent variables included perceived susceptibility, severity, barrier, and benefit in accordance with HBM. The dependent variable comprised toothbrushing …
Euphorbia Tirucalli L. Accelerates Mandibular Bone Healing: Analysis Of Pmns, Fibroblasts, Osteoblasts, And Osteoclasts In Wistar Rats, Florence Meliawaty, Juni Handajani, Heni Susilowati, Poerwati Soetji Rahajoe, Euis Reni Yuslianti, Rahmadaniah Khaerunnisa, Kertamaya Sundawan, Adzra Farah Fajrina, Lorintan Sitepu
Euphorbia Tirucalli L. Accelerates Mandibular Bone Healing: Analysis Of Pmns, Fibroblasts, Osteoblasts, And Osteoclasts In Wistar Rats, Florence Meliawaty, Juni Handajani, Heni Susilowati, Poerwati Soetji Rahajoe, Euis Reni Yuslianti, Rahmadaniah Khaerunnisa, Kertamaya Sundawan, Adzra Farah Fajrina, Lorintan Sitepu
Journal of Dentomaxillofacial Science
Objective: The present study aimed to elucidate the therapeutic potential of Euphorbia tirucalli L. stem extract in accelerating mandibular bone defect healing through the modulation of inflammatory and regenerative cellular responses, including polymorphonuclear cells, fibroblasts, osteoblasts, and osteoclasts in Wistar rats.
Material and Methods: A laboratory-based experimental study with a randomized post-test only control group design was conducted using 40 male Wistar rats. Standardized mandibular defects were created in the symphysis region utilizing a low-speed round bur. The animals were randomly assigned into four groups, including a negative control and three treatment groups receiving topical Euphorbia tirucalli L. stem extract …
Role Of Notch Intracellular Domain 1 In Lung Metastasis Of Salivary Gland Adenoid Cystic Carcinoma, Hermin Aminah Usman, Rakhmiana Rakhmiana, Birgitta Maria Dewayani, Seto A. Sadputranto, Bethy Suryawati Hernowo, Hasrayati Agustina, Anglita Yantisetiasti, Etis Primastari, Okky Husain, Nia Nuraeni
Role Of Notch Intracellular Domain 1 In Lung Metastasis Of Salivary Gland Adenoid Cystic Carcinoma, Hermin Aminah Usman, Rakhmiana Rakhmiana, Birgitta Maria Dewayani, Seto A. Sadputranto, Bethy Suryawati Hernowo, Hasrayati Agustina, Anglita Yantisetiasti, Etis Primastari, Okky Husain, Nia Nuraeni
Journal of Dentomaxillofacial Science
Background: Adenoid cystic carcinoma (AdCC) is a malignant salivary gland tumor characterized by a high rate of metastasis. One of the recurrent genetic alterations in AdCC involves NOTCH1, leading to the activation and release of NOTCH intracellular domain 1 (NICD1). The epithelial–mesenchymal transition (EMT), a key process in tumor metastasis, is regulated by NICD1 and Snail. This study aimed to investigate the association between NICD1 expression, Snail expression, and pulmonary metastasis in AdCC.
Methods: This analytical observational case–control study included AdCC samples with and without pulmonary metastasis. NICD1 and Snail immunoexpression levels were assessed using histoscore and analyzed using …
Bone Regeneration On Modified Implant Surfaces: A Systematic Review, Irfan Dammar, Ratna S. Dewi, Ira Tanti, Lisa R. Amir, Lilies D. Sulistyanti, Yuniarti Soeroso
Bone Regeneration On Modified Implant Surfaces: A Systematic Review, Irfan Dammar, Ratna S. Dewi, Ira Tanti, Lisa R. Amir, Lilies D. Sulistyanti, Yuniarti Soeroso
Journal of Dentomaxillofacial Science
Objective: To describe effective implant surface modifications (ISMs) that enhance bone regeneration.
Methods: This systematic review involved literature searches in the PubMed, Scopus, and ScienceDirect databases to identify both in vivo and in vitro randomized controlled trials investigating bone regeneration on modified implant surfaces. The search was conducted using predefined population, intervention, comparison, outcome, and study design criteria, eligibility criteria, and relevant MeSH terms. Article selection followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram.
Results: Various ISMs were identified, including elastin-like polypeptides, hydroxyapatite, doxycycline, sandblasted large-grit acid-etched, and others. The average bone-to-implant contact (BIC) in experimental …
Advancing Dental Research: From Biomaterials And Precision Dentistry To Population-Based Oral Health And Service Delivery, Acing H. Mude, H. Hasanuddin, Nisrina E. Nasrun, Muhammad Ikbal
Advancing Dental Research: From Biomaterials And Precision Dentistry To Population-Based Oral Health And Service Delivery, Acing H. Mude, H. Hasanuddin, Nisrina E. Nasrun, Muhammad Ikbal
Journal of Dentomaxillofacial Science
Objective: This editorial review aims to synthesize the thematic contributions of 14 manuscripts published in Journal of Dentomaxillofacial Science Volume 11 Issue 1, and to identify emerging scientific trends across contemporary dental research.
Methods: A descriptive thematic review was conducted by systematically analyzing the titles, abstracts, study objectives, methodologies, and key findings of all included manuscripts. Articles were grouped through qualitative synthesis into major thematic categories to capture the shared scientific directions and methodological patterns.
Results: The analysis identified six major thematic clusters: (1) biomaterials and oral tissue regeneration, (2) oral hygiene, saliva, microbiology, and vulnerable populations, (3) oral pathology …
Curating Black Knowledge In Academic Libraries: A Qualitative Study, Monique Christian-Long
Curating Black Knowledge In Academic Libraries: A Qualitative Study, Monique Christian-Long
Education Policy and Leadership Theses and Dissertations
Academic librarians play a critical role in shaping access to scholarly information. However, the intellectual contributions of African American scholars have often been marginalized in academia through structural inequities, archival gaps, and historical patterns of exclusion. This qualitative study explores how academic librarians understand and use their roles to advance access to African American scholarly contributions. This study is guided by Black Critical Race Theory (Dumas & Ross, 2016) and Ray’s (2019) Theory of Racialized Organizations, and examines how institutional structures, professional norms, and resource allocation influence librarians’ efforts to curate, preserve, and promote Black knowledge. The data was collected …
An Unnecessary Burden: Why It Is Time To Eliminate Mcdonnell Douglas From Ada Failure-To-Accommodate Claims, Jonathan G. Jain
An Unnecessary Burden: Why It Is Time To Eliminate Mcdonnell Douglas From Ada Failure-To-Accommodate Claims, Jonathan G. Jain
Missouri Law Review
Several strangers sit together in a room, staring at three black lines on a white card. Their task seems simple: choose the line that matches the length of a line printed on a second card. One by one, the strangers correctly choose the matching line, and the task repeats with new white cards and new black lines. The correct answer is always obvious, but after a few rounds, one man suddenly finds himself alone in giving the correct response. What he does not know is that the others have been instructed to begin choosing incorrect lines. Eventually, despite what his …
Late-Onset Legg-Calvé-Perthes Disease Treated With Varus Derotation Femoral Osteotomy: A Case Report, Mark Gamadia, Sami Habboub, Bianca Gamadia, Himanshu Panchal
Late-Onset Legg-Calvé-Perthes Disease Treated With Varus Derotation Femoral Osteotomy: A Case Report, Mark Gamadia, Sami Habboub, Bianca Gamadia, Himanshu Panchal
Student Publications
Introduction: Legg-Calvé-Perthes disease (LCPD) is categorized as idiopathic avascular necrosis of the femoral head, most common in children between the ages of 5 and 7. Prognosis is strongly influenced by age and lateral pillar classification, with children older than 8 years and those with Herring Group C disease typically experiencing poor outcomes. Delayed diagnosis represents a significant barrier to care, often limiting treatment options and worsening prognosis. This case highlights such a scenario while demonstrating that favorable functional and radiographic results remain achievable through meticulous surgical containment in late-presenting, severe disease.
Case report: An 11-year-old boy with no history of …
Driveline Infections Among Patients Supported With Left Ventricular Assist Devices: A Single Center Sixteen-Year Longitudinal Profile, Anh Nguyen, Alexis Shafii, Gabriel Loor, Andrew Civitello, O Howard Frazier, Todd Rosengart, Kenneth Liao
Driveline Infections Among Patients Supported With Left Ventricular Assist Devices: A Single Center Sixteen-Year Longitudinal Profile, Anh Nguyen, Alexis Shafii, Gabriel Loor, Andrew Civitello, O Howard Frazier, Todd Rosengart, Kenneth Liao
Faculty, Staff and Students Publications
Background: Left ventricular assist device (LVAD) driveline infections significantly impact patient outcomes. This study aimed to identify their risk factors.
Methods: We analyzed LVAD data from our institutional Intermacs database (January 1, 2008-December 31, 2023), combining primary implants and pump exchanges. Patient characteristics were summarized as frequencies for categorical variables and median (IQR) for continuous variables. The nature of repeated infection events was handled by the Andersen-Gill method within a multivariable Cox proportional hazards model for cause-specific hazard of driveline infections, accounting for death and heart transplant as competing risks.
Results: Our cohort included 1026 LVAD implants. Median patient age …
The Impact Of Estrogen Replacement During Perimenopause On Lung Function And Airway Inflammation In The Vcd Mouse Model, William P Pederson, Laurie Michelle Ellerman, Riley D Hellinger, Joselyn Joanna Rojas Quintero, Francesca Polverino, John P Konhilas, Julie G Ledford
The Impact Of Estrogen Replacement During Perimenopause On Lung Function And Airway Inflammation In The Vcd Mouse Model, William P Pederson, Laurie Michelle Ellerman, Riley D Hellinger, Joselyn Joanna Rojas Quintero, Francesca Polverino, John P Konhilas, Julie G Ledford
Faculty, Staff and Students Publications
Background:
Menopause associated asthma impacts a subset of women and is less responsive to current treatments. Mechanisms driving this late onset asthma are unknown. We recently developed a mouse model of menopause associated asthma using a combination of 4-Vinylcyclohexene Diepoxide (VCD) and House Dust Mite (HDM) exposures. The goal of this study was to determine how hormone replacement therapy during perimenopause impacts lung function and inflammation.
Methods:
The experimental groups included menopausal mice (VCD) with and without exposure to HDM (to model allergic airways disease) and menopausal mice with and without hormone replacement therapy (HRT; via estrogen pellet implantation). Lung …
Effects Of Photobiomodulation On Oral Mucositis, Oral Pain, Xerostomia, Salivary Flow Rate, And Quality Of Life In Patients With Head And Neck Cancer: A Systematic Review And Meta-Analysis, Mônica N.M. Pedroso, Anderson Rech, Natalia Casagrande, Júlia F. Pissaia, Julia S. Zardo, Vitória L. Borges, Stephanie R. Bombana, Cindranne Torres Muller, Priscila Casara, Janaína Brollo, Claudio P. Júnior, Carin W. Gallon, Pedro Lopez
Effects Of Photobiomodulation On Oral Mucositis, Oral Pain, Xerostomia, Salivary Flow Rate, And Quality Of Life In Patients With Head And Neck Cancer: A Systematic Review And Meta-Analysis, Mônica N.M. Pedroso, Anderson Rech, Natalia Casagrande, Júlia F. Pissaia, Julia S. Zardo, Vitória L. Borges, Stephanie R. Bombana, Cindranne Torres Muller, Priscila Casara, Janaína Brollo, Claudio P. Júnior, Carin W. Gallon, Pedro Lopez
Research outputs 2022 to 2026
Purpose: To systematically review and analyze the effects of photobiomodulation on oral mucositis, xerostomia, salivary flow rates, oral pain, and quality of life in patients with head and neck cancer. Methods: A systematic search of six databases was conducted up to April 2025. Eligible randomized controlled trials (RCTs) examined the effects of photobiomodulation on the specified outcomes in patients with head and neck cancer. Pooled estimates (risk ratio [RR] and standardized mean difference [SMD]) were calculated using a three-level mixed-effects meta-analysis. Results: Thirty-three articles describing 30 RCTs (n = 1748) were included. Photobiomodulation significantly reduced the risk of severe oral …
Facilitating Food Security Systems Change In Regional Australia Through A Strengths-Based, Co-Design Process, Isabelle Chiera, Doe, Melissa Stoneham, Amanda Devine, Stephanie L. Godrich
Facilitating Food Security Systems Change In Regional Australia Through A Strengths-Based, Co-Design Process, Isabelle Chiera, Doe, Melissa Stoneham, Amanda Devine, Stephanie L. Godrich
Research outputs 2022 to 2026
Food security is a multifaceted, ‘wicked’ issue that refers to the sufficient physical, social, and economic access to food at all times. Given its complexity, food security action requires a systems-based, collaborative, and adaptive approach. This paper outlines the application of a strengths-based, co-design process to support food security systems change among government and community-led initiatives operating in rural, regional, and remote areas of Western Australia. Baseline, semistructured interviews were conducted with leaders of food initiatives to understand whether and how the initiatives were contributing to food security systems change and identify the ‘windows of opportunity’ where initiatives could be …
Impact Of Cannabis And Cannabis Legalization On Us Atrial Septal Defect Rates, Albert Stuart Reece, Hulse
Impact Of Cannabis And Cannabis Legalization On Us Atrial Septal Defect Rates, Albert Stuart Reece, Hulse
Research outputs 2022 to 2026
Atrial septal defect (ASD) affects 1:11.3 children in some US states; however, the antecedents of these trends are yet to be identified. A total of 1882 ASD rates (ASDRs) for 2003–2020 were sourced from the National Birth Defects Prevention Network reports. A total of 406,893 ASDs are reported. Substance (cigarettes, binge alcohol, cannabis, cannabinoids, analgesics, cocaine) exposure data were taken from the National Survey of Drug Use and Health. Income and ethnicity data were derived from the US Census. Adjustment was performed by mixed effects, survey and generalized additive regression. Causal analysis was by inverse probability weighting and E-values. Data …
Influence Of Simulator Physical Fidelity And Immersion On Decision-Making Skill, Presence, And Cognitive Load, Zachariah G. Hoyne, Morris-Binelli, Sean Müller, Benjamin Piggott, Paola Chivers, Evan Dekker
Influence Of Simulator Physical Fidelity And Immersion On Decision-Making Skill, Presence, And Cognitive Load, Zachariah G. Hoyne, Morris-Binelli, Sean Müller, Benjamin Piggott, Paola Chivers, Evan Dekker
Research outputs 2022 to 2026
In a variety of domains such as law enforcement and sport, virtual reality is being explored to simulate field-based decision-making contexts. 360-degree video virtual reality (360VR) is innovative as it can immerse the user in a simulated environment, present egocentric, stereoscopic vision and allows for head movements to perceive visual information. However, it is unknown whether physical, rather than psychological fidelity, is crucial for performance, and its impact upon cognitive load, relative to immersion. This study investigated simulator fidelity, presence, and cognitive load across immersion (two-dimensional video and 360VR) in an exemplar sport-specific decision-making task. Thirty skilled Australian Rules Football …
Mood Monitoring In Schools: A Promising Alternative To Single-Time-Point Screening, Shane L. Rogers, Brown, Kathryn Campbell, Matthew Goulding
Mood Monitoring In Schools: A Promising Alternative To Single-Time-Point Screening, Shane L. Rogers, Brown, Kathryn Campbell, Matthew Goulding
Research outputs 2022 to 2026
School-based mental health screening typically relies on single-time-point assessments, which assume that students’ emotional well-being is sufficiently stable for classification based on a single measurement. The present study examined this assumption by evaluating the stability of emotional well-being classifications under repeated mood monitoring. Students from two secondary schools (United Kingdom, n = 413; Australia, n = 354) completed the Brief Emotional Experience Scale weekly across six to seven weeks. Emotional well-being classifications were examined relative to a predefined low well-being threshold to assess stability across time, and a post-monitoring survey examined students’ self-reported perceptions of the monitoring experience. Most students …
Rapid Isometric Hamstring Strength Scores From Professional Soccer Players At Pre-Season: Positional Differences And Relationship To Peak Force, Nicholas Joel Ripley, Ross, Jack Fahey, Christopher Bramah, Paul Jones, Paul Comfort
Rapid Isometric Hamstring Strength Scores From Professional Soccer Players At Pre-Season: Positional Differences And Relationship To Peak Force, Nicholas Joel Ripley, Ross, Jack Fahey, Christopher Bramah, Paul Jones, Paul Comfort
Research outputs 2022 to 2026
The assessment of rapid force within a single joint assessment is becoming common practice within elite sport environments. Recent observations have highlighted that rapid force maybe more sensitive to fatigue than peak force within the hamstrings. Yet limited information exists on rapid force production in elite male soccer players. Eighty-nine senior professional men’s soccer players (age; 24.2±5.1 years, height; 1.83±0.05 m, mass; 78.95±7.53 kg) participated within the present study they performed two isometric assessments at joint angles of 30° and 90° of hip flexion and knee. They performed three trials with mean and standard deviation determined differences between soccer positions …
Self-Management Challenges And Psychosocial Support Needs In Clean Intermittent Catheterization: A Qualitative Study Of Individuals With Neurogenic Bladder And Caregivers, Lianyu Zou, Xiaomei Wu, Shun Chen, Shuluan Feng, Xiaohua Huang, Weiting Liu
Self-Management Challenges And Psychosocial Support Needs In Clean Intermittent Catheterization: A Qualitative Study Of Individuals With Neurogenic Bladder And Caregivers, Lianyu Zou, Xiaomei Wu, Shun Chen, Shuluan Feng, Xiaohua Huang, Weiting Liu
Research outputs 2022 to 2026
Background – Clean intermittent catheterization (CIC) is widely regarded as the preferred approach to bladder management for individuals with neurogenic bladder (NB). Nevertheless, a considerable gap persists between evidence and clinical practice: patients and caregivers frequently encounter self-management barriers that compromise clinical outcomes during CIC. This qualitative study explores these barriers to provide an empirical foundation for developing tailored strategies that improve quality of care. Design – A descriptive qualitative study. Methods – From August to October 2025, a convenience sampling method was employed to recruit 16 participants individuals with NB or their long-term caregivers from the Department of Rehabilitation …
Setting Research Priorities For The Use Of Digital Technology In The Self-Management Of Heart Health: The Results Of The James Lind Priority Setting Partnership, Lis Neubeck, Simon Nichols, Nicola Straiton, Louise J. Dunford, Amitava Banerjee, Susan Dawkes, Donna Fitzsimons, Maria Hayes, Alistair Lawson, Abigail A. Lyons, Mary Mcauley, Jill Mclaggan, Richard Mindham, Nicholas L. Mills, Rakesh Modi, Alice Pearsons, Amanda Pitkethly, Fiona E. Strachan, Coral L. Hanson
Setting Research Priorities For The Use Of Digital Technology In The Self-Management Of Heart Health: The Results Of The James Lind Priority Setting Partnership, Lis Neubeck, Simon Nichols, Nicola Straiton, Louise J. Dunford, Amitava Banerjee, Susan Dawkes, Donna Fitzsimons, Maria Hayes, Alistair Lawson, Abigail A. Lyons, Mary Mcauley, Jill Mclaggan, Richard Mindham, Nicholas L. Mills, Rakesh Modi, Alice Pearsons, Amanda Pitkethly, Fiona E. Strachan, Coral L. Hanson
Research outputs 2022 to 2026
Aims: There are wide inequalities in access to cardiovascular care, and risk factors such as obesity, high blood pressure, and physical inactivity are often not well managed. We aim to identify the most important questions about how digital technologies can help people and their carers prevent cardiovascular disease and improve access to care. Methods and results: A priority setting partnership that aimed to generate a top 10 list of research priorities for the use of digital technology in the prevention and management of heart disease and heart conditions in the UK and Ireland, with equal input by people with lived …
3-Deoxyanthocyanidins Inhibit Β-Amyloid Aggregation, Toxicity, And Mitochondrial Dysfunction: Evidence From Mc-65 Cells And Molecular Dynamics Simulations, Rasheed A. Abdulraheem, Ammar U. Danazumi, Philipp Nitschke, Luke Gray Whiley, Abdulrahman Ibrahim Tudu, Ranil Coorey, Zhoyu Li, Prashant Bharadwaj, Vijay Jayasena, Stuart K. Johnson, Ralph N. Martins, W. M.A.D.Binosha Fernando
3-Deoxyanthocyanidins Inhibit Β-Amyloid Aggregation, Toxicity, And Mitochondrial Dysfunction: Evidence From Mc-65 Cells And Molecular Dynamics Simulations, Rasheed A. Abdulraheem, Ammar U. Danazumi, Philipp Nitschke, Luke Gray Whiley, Abdulrahman Ibrahim Tudu, Ranil Coorey, Zhoyu Li, Prashant Bharadwaj, Vijay Jayasena, Stuart K. Johnson, Ralph N. Martins, W. M.A.D.Binosha Fernando
Research outputs 2022 to 2026
Accumulation of amyloid-beta (Aβ42) senile plaques in the brain is a hallmark of Alzheimer's disease (AD). Although some drug have been approvaled recently, none has demonstrated robust disease-modifying outcome. The 3-deoxyanthocyanidins (3-DXA) and their derivatives represent a more stable class of polyphenols, present at uniquely high concentrations in sorghum grains. Although 3-DXA exhibit strong potential to modulate protein aggregation processes, their effects on AD pathology remain unexplored. In this study, we investigated the inhibitory effects of three 3-DXA derivatives, apigeninidin chloride (AC), luteolinidin chloride (LC), and 7-methoxy apigeninidin (7-MAC), on Aβ42 aggregation and associated neurotoxicity. Thioflavin T fluorescence assay was …
Enhancing Co2 Adsorption And Co2/N2 Separation Performance By Incorporating Calcium In Mil-53 (Al), Hussein Rasool Abid, Hussein Znad, Nabil Majd Alawi, Farhan Lafta Rashid, Anmar Dulaimi, Amer Alanazi, Alireza Keshavarz, Stefan Iglauer, Shaobin Wang
Enhancing Co2 Adsorption And Co2/N2 Separation Performance By Incorporating Calcium In Mil-53 (Al), Hussein Rasool Abid, Hussein Znad, Nabil Majd Alawi, Farhan Lafta Rashid, Anmar Dulaimi, Amer Alanazi, Alireza Keshavarz, Stefan Iglauer, Shaobin Wang
Research outputs 2022 to 2026
Global warming is primarily driven by the rapid accumulation of carbon dioxide (CO₂) in the atmosphere. Metal–organic frameworks (MOFs) have emerged as promising materials for mitigating CO₂ emissions due to their tunable porosity, large surface area, and structural flexibility. Among them, MIL-53(Al) has attracted widespread interest owing to its excellent thermal and chemical stability. Recent studies show that modifying MOFs with secondary metals can significantly enhance their CO₂ adsorption performance. In this work, a one-pot synthesis method was employed to incorporate calcium (Ca), functioning as a Lewis basic metal, into the MIL-53(Al) framework to produce a series of bimetallic materials: …
Combined Effect Of Sarcopenia And Impaired Respiratory Function On All-Cause Death: A Nationwide Cohort Study, Chutao Wu, Dan Wu, Mu Li, Senrong Lu, Yukai Wang, Yulong Lan
Combined Effect Of Sarcopenia And Impaired Respiratory Function On All-Cause Death: A Nationwide Cohort Study, Chutao Wu, Dan Wu, Mu Li, Senrong Lu, Yukai Wang, Yulong Lan
Research outputs 2022 to 2026
Background: Respiratory fitness and sarcopenia status have been reported to be cross-sectionally linked with each other and increase mortality risk. However, little is currently known regarding the connection between impaired respiratory function and sarcopenia and their joint effect on future death risk. Methods: This study included 12 027 participants (50.8% were women; mean [SD] age, 58.9 [9.3] years) from a nationwide, prospective cohort in China (China Health and Retirement Longitudinal Study). Respiratory function was assessed by peak expiratory flow (PEF). Sarcopenia status was assessed according to the Asian Working Group for Sarcopenia 2019 (AWGS 2019) criteria. Time-to-event survival analyses and …
Engineering Zinc Anodes Through Advanced Manufacturing Strategies For Next-Generation Zinc–Air Batteries, Yasir Arafat, Kareem Bakhsh, Muhammad Rizwan Azhar
Engineering Zinc Anodes Through Advanced Manufacturing Strategies For Next-Generation Zinc–Air Batteries, Yasir Arafat, Kareem Bakhsh, Muhammad Rizwan Azhar
Research outputs 2022 to 2026
Rechargeable zinc–air batteries (ZABs) are promising next-generation energy storage systems due to their high energy density, intrinsic safety, and low cost. Nevertheless, commercial deployment of Zn anodes is hampered by persistent challenges like dendrite formation, deformation, passivation, corrosion, and the hydrogen evolution reaction. This review systematically highlights the critical relationship between anode morphology and electrochemical performance and discusses recent advances in advanced manufacturing strategies for Zn anodes. Additive manufacturing approaches, such as 3D printing, enable the fabrication of porous and tunable Zn electrodes with enhanced surface area and uniform ion flux distribution. Furthermore, advanced materials processing techniques like alloying, coatings, …
Lactation-Stage Specific Protein Shifts In Koala Milk Mirror The Joey's Growth Needs, Manujaya W. Jayamanna Mohottige, Angéla Juhász, Emma Peel, Mitchell G. Nye-Wood, Katherine A. Farquharson, Tawfeek Khedr, Katherine Belov, Carolyn J. Hogg, Michelle L. Colgrave
Lactation-Stage Specific Protein Shifts In Koala Milk Mirror The Joey's Growth Needs, Manujaya W. Jayamanna Mohottige, Angéla Juhász, Emma Peel, Mitchell G. Nye-Wood, Katherine A. Farquharson, Tawfeek Khedr, Katherine Belov, Carolyn J. Hogg, Michelle L. Colgrave
Research outputs 2022 to 2026
AbstractKoalas (Phascolarctos cinereus) give birth to highly altricial young that rely on maternal milk for nutritional support and immune protection in the first year of life. This study applied proteomics to analyse stage-specific shifts in the koala milk proteome across early-, mid-, and late-lactation. Proteins were extracted from seven samples and analysed using liquid chromatography-tandem mass spectrometry. Quantitative profiling identified 874, 1220, and 498 proteins in early-, mid- and late-lactation stages, respectively. The most abundant proteins—including β-lactoglobulin, caseins, clusterin, trichosurin, albumin and lactotransferrin—were consistently detected across all stages, reflecting crucial roles in nutrition, immune function, and detoxification. Protein–protein interaction analyses …
Assessment Of Thickness-Dependent Recombination Mechanisms And Realistic Performance Limits In Csbi₃I₁₀ Lead-Free Perovskite Solar Cells, Samiul Sadek, Ayan Saha, Jegadesan Subbiah, Mohammad Tariqul Islam, Mohammad Junaebur Rashid, Mohammad Aminul Islam, Gufran Umar Alam Shaikh, Wan Zulhafizhazuan Bin Wan Jusoh, Mohammad Nur-E-Alam, Puvaneswaran Chelvanathan, Mohd Adib Ibrahim
Assessment Of Thickness-Dependent Recombination Mechanisms And Realistic Performance Limits In Csbi₃I₁₀ Lead-Free Perovskite Solar Cells, Samiul Sadek, Ayan Saha, Jegadesan Subbiah, Mohammad Tariqul Islam, Mohammad Junaebur Rashid, Mohammad Aminul Islam, Gufran Umar Alam Shaikh, Wan Zulhafizhazuan Bin Wan Jusoh, Mohammad Nur-E-Alam, Puvaneswaran Chelvanathan, Mohd Adib Ibrahim
Research outputs 2022 to 2026
Lead-free perovskite solar cells (PSCs) offer a promising, environmentally sustainable alternative to their lead-based counterparts, yet their performance is often constrained by charge transport and recombination limitations. This study presents a comprehensive numerical investigation into the thickness-dependent performance of lead-free bismuth-based PSCs employing CsBi₃I₁₀ as the absorber layer. Through systematic variation of the absorber, electron transport layer (ETL), and hole transport layer (HTL) thicknesses within a planar FTO/TiO₂/CsBi₃I₁₀/Spiro-OMeTAD/Ag architecture modeled using SCAPS-1D, an optimal absorber thickness range of 0.5–1.0 µm is identified. Under idealized conditions, a peak power conversion efficiency (PCE) of 21.62% is predicted, primarily to illustrate thickness-dependent trends. …
Development, Performance Analysis And Application Of Polymer Inclusion Membranes: A Critical Review, Shayan Abrishami, Mahsa Golmohammadi, Matthew Myers, Masoumeh Zargar, Antonia Pérez De Los Ríos, Francisco José Hernández-Fernández, Amir Razmjou
Development, Performance Analysis And Application Of Polymer Inclusion Membranes: A Critical Review, Shayan Abrishami, Mahsa Golmohammadi, Matthew Myers, Masoumeh Zargar, Antonia Pérez De Los Ríos, Francisco José Hernández-Fernández, Amir Razmjou
Research outputs 2022 to 2026
Polymer Inclusion Membranes (PIMs) have emerged as sustainable separation platforms that integrate carrier-mediated selectivity within stable polymeric matrices, eliminating drawbacks of conventional solvent extraction such as solvent loss and emulsion formation. This review examines the fundamental principles, recent developments, and performance characteristics of PIMs, emphasizing design, fabrication, and operational optimization. The three essential components, base polymers, plasticizers, and carriers are systematically analysed alongside their synergistic effects on membrane stability, selectivity, and transport efficiency. Emerging materials including ionic liquids and deep eutectic solvents as dual-function plasticizers/carriers receive particular attention. Preparation methods are critically evaluated, including solution casting, phase inversion, and thermal …