Digital Commons Network^™

Integrated Biotechnological Strategies For Planetary Health And Ecosystem Restoration, Duygu T. Yildirim, A. Baki Yildirim, Donald Martin, Tommaso Beccari, Oscar Vicente, Iza Radecka, Fideline Tchuenbou-Magaia, Robert Marks, Ratnesh Lal, Satya Prakash, Adam Mechler, Mario Petrov Milkov, Svetlana Fotkova Georgieva, Ilia Iliev, Radka Kaneva, Nuriye Gokce, Galina Aleksieva Yaneva, Nadya Vasileva Agova, Nikoleta Dobromirova Ivanova, Izem Olcay Sahin, Mariya Kiryakova Tsvetkova, Ivelin Rosenov Iliev, Michel Salzet, Kisung Ko, Michele Maffia, Matteo Bertelli, Isabelle Fournier, Lejla Pojskic, Qun Sun, Lembit Nei, Reynir Armgrisson

Research Outputs: 2025-Present

The escalation of ecological degradation, marked by climatic instability, precipitous biodiversity loss, and systemic chemical infiltration, necessitates a shift toward integrated biotechnological intervention. This analysis considers how the trajectory of diverse advanced methodologies, including environmental DNA (eDNA) surveillance, CRISPR-based genetic restitution, and synthetic biology-driven bioremediation, might be synthesized into a unified Planetary Health Framework. By exploring the convergence of high-precision genomic engineering, AI-augmented bioinformatic modeling, and the tenets of a circular bio-economy, we examine the capacity of technological intervention to ameliorate ecological stressors and restore critical ecosystems. Moving beyond the constraints of conventional conservation, this discourse explores frontier solutions in …

Traditional And Machine-Learning Equalization Techniques For Bandwidth-Limited Short-Reach Optical Communication Channels, Abdullah Khawatmi

Theses

This thesis investigates equalization techniques for bandwidth-limited short-reach optical communication systems, with a focus on Visible Light Communication (VLC) and Step-Index Plastic Optical Fiber (SI-POF) links. Commercial light-emitting diodes and photodiode receivers impose severe bandwidth constraints, inter-symbol interference, and noise sensitivity, which fundamentally limit achievable data rates. The work addresses these impairments through systematic evaluation of traditional digital signal processing–based equalizers and modern machine-learning-based post-equalization methods. The primary aim of this thesis is to enhance the achievable data rate and reliability of commercial short-reach optical links while maintaining practical computational complexity. Specifically, the objectives are to (i) design and experimentally …

Efficient Energy Management In Networked Microgrids Using Multi-Agent Deep Reinforcement Learning In The Presence Of Uncertainties, Ayodele Benjamin Chukwuyem

Dissertations

Microgrid technology is essential in facilitating the transition to smart energy grids in developed countries and mitigating energy poverty in developing countries, particularly in areas where grid extensions are not feasible. Recently, the concept of networked microgrids (NMGs) has garnered tremendous attention due to the plausibility of interactions among interconnected microgrids leading to power networks that are more resilient, reliable, and stable. However, because each microgrid has diverse distributed generation resources (renewables and controllable generators) and each microgrid operator (MO) has different objectives, coordinated energy management is required to satisfy local and system-wide goals under conditions with significant uncertainty. Existing …

Visual And Tactile Motion Cues Enhance The Categorisation Of Novel Object Shapes, Martina A. Seveso, Rebecca J. Hirst, Alan O’Dowd, Ivan Camponogara, Fiona N. Newell

All Works

Object categorisation is a fundamental cognitive process, involving the integration of information across the senses. We investigated, using smartphones, whether visual and tactile motion cues could enhance object category learning and generalisation to novel object shapes. Two categories of similar shapes were associated with specific correlated visual and tactile vibration motion cues. After learning object categories, participants were assessed on categorisation of learned and novel objects across four cue conditions: shape-only, shape-visual motion, shape-tactile motion, and shape-visual and tactile motion. We also assessed if accuracy was influenced by blocked versus interleaved cue-conditions at test. In Experiment 1, we found more …

Cas Honor Symposium Program, Spring 2026, College Of Arts & Sciences Honors Program

College of Arts & Sciences Honors in the Major Symposium

No abstract provided.

Instructional Leadership Practices In Dual Language Bilingual Education: A Reflective Growth Model Perspective, Selene Canales-Garcia, Velma D. Menchaca, Michelle Abrego, Jose A. Ruiz-Escalante, George Padilla

Organization and School Leadership Faculty Publications

As dual language programs expand across the U.S., school leaders face growing pressure to support bilingual educators amid ongoing teacher shortages. This qualitative case study explores bilingual teachers’ perceptions of their principal’s instructional leadership practices at a dual language elementary school in South Texas. Guided by the Blasé and Blasé Reflective Growth Model (1999, 2000), the study highlights leadership behaviors that promote teacher reflection, collaboration, and professional growth. Findings reveal that supportive leadership—rooted in trust, shared decision-making, and targeted professional development—enhances teacher capacity and strengthens bilingual program implementation.

Development And Acceptability Of A Patient Decision Aid For People With Degenerative Cervical Myelopathy: An International Mixed-Methods Study, Andrew R. Gamble, David B. Anderson, Marnee J. Mckay, Benjamin M. Davies, Sophie Macpherson, James Van Gelder, Tammy Hoffmann, Kirsten Mccaffery, Samuel X. Stevens, Carlo Ammendolia, Rohil V. Chauhan, Carl M. Zipser, Timothy F. Boerger, Lindsay A. Tetreault, Michael G. Fehlings, Elanor Dustan, Carolyn Nugent, Helen Holmgren, Andreas K. Demetriades, Justin M. Lantz, Rana Dhillon, Chris G. Maher, Joshua R. Zadro

Biomedical Engineering Faculty Research and Publications

Objectives To develop and user-test a patient decision aid for people diagnosed with degenerative cervical myelopathy and who are considering surgery.

Design Mixed-methods study describing the development of a patient decision aid.

Setting A draft decision aid was developed by a multidisciplinary steering group (including study authors with degenerative cervical myelopathy, health professionals and researchers) informed by the best available evidence, authorship consensus and existing patient decision aids.

Participants Patient-participants and health professional-participants who manage people with degenerative cervical myelopathy were recruited through social media and the steering group’s research and practice network. Quantitative questionnaires were used to gather baseline …

The Diamond Collar: One Woman’S Leadership Disruption, Alteration, And Reemergence, An Autoethnographic Study About Ipv, Nancy Flagg Phd

All Student Scholarship

This dissertation explores one woman’s leadership persistence, decline, and reemergence under the assault of Intimate Partner Violence (IPV). About 30% of women worldwide (World Health Organization [WHO], 2025) and over 42 % of U.S. women (Centers for Disease Control and Prevention [CDC], 2022) have experienced physical and/or sexual violence by an intimate partner. IPV has impacts that reverberate through communities and harm the leadership potentials of women leaders. Women’s leadership parity has increased, then halted, and even shrunk in some sectors, even in woman dominated fields (United Nations, 2025). This coincides with an uptick in IPV since COVID (Uzoho et …

Powell’S Overland Trip To The Grand Canyon, Daniel Styer

Faculty & Staff Scholarship

No abstract provided.

Sounding W. B. Yeats’S “Cuchulain Comforted”, David Sergeant

School of Law, Humanities and Social Sciences

No abstract provided.

Relational Practices Underpinning Person-Centred Care In Long-Term Residential Care Settings., Gary Hodge, Sam Ebden, Susie Pearce

School of Nursing and Midwifery

Recent figures indicate that there are just over 441,000 people living in long-term residential care homes across the United Kingdom (UK) (Berg, 2025), of which 70% are living with dementia or a severe cognitive impairment (Alzheimer’s Society, 2024). The percentage of people living in permanent residential aged care with dementia in Australia is slightly lower (54%) but still represents most residents and is rising (AIHW, 2025; Dementia Australia, 2025).This article is based on the findings and reflections of a qualitative multiple-case study exploring person-centred care across seven residential care homes in the United Kingdom (UK; Hodge et al., 2023). Findings …

Evidence Base To Inform Health Service Configuration For Abortion Provision: The Sacha (Shaping Abortion For Change) Multi-Component Study, Kaye Wellings, Rebecca S. French, Annette Aronsson, Paula Baraitser, Sharon Cameron, Caroline Free, Louise Keogh, Maria Lewandowska, Patricia Lohr, Rebecca Meiksin, Ona Mccarthy, Clare Murphy, Wendy Norman, Melissa Palmer, Jennifer Reiter, Natasha Salaria, Rachel Scott, Jill Shawe, Sally Sheldon, Geoff Wong

School of Nursing and Midwifery

Background: Significant changes to the nature and context of abortion provision are taking place in the United Kingdom. Empirical evidence is needed to guide efforts to respond to these changes. Objective(s): To provide an evidence base to inform optimal configuration of health services and systems in response to current and future changes in abortion provision in the UK. Design and methods: Observational study comprising five integrated components: (1) a realist review to generate evidence to guide optimal abortion provision and a scoping review of interventions aimed at preparing non-specialist health professionals to provide abortion care and support; (2) country-based case studies identifying transferable …

Using Expert Elicitation And Systems Mapping To Support Social Innovation In The (Blue) Food System: The Case Of The Uk’S Plymouth Fish Finger, Clare Pettinger, Kelly Parsons, Yanaina Irazu Chavez-Ugalde, Louise Hunt, Carol Wagstaff

School of Health Professions

Background: The imperative for food system transformation is well known, yet to date there has been minimal emphasis on the blue food system [foods sourced from marine and freshwater environments]. Generally, a food systems approach should shift away from linear and move towards more systems thinking to embrace complexity. This paper focuses on a local social innovation project (Plymouth Fish Finger (PFF)) which has pioneered localising the blue food system. This study aimed to elicit how the (policy and practice) system around the PFF can be appraised to optimise social innovation practices for (blue) food system transformation. Methods: Expert elicitation …

Variation In Corneal Biomechanical Properties Following Continuous Cross-Linking Treatment, Chenhao Zhao, Xinyu Yao, Yewei Zhao, Hongjiang Wu, Xuanya Tong, Daniela Oehring, Lan Yang, Xiaofei Zhou, Ying Li, Yanjie Shen, Yufeng Ye, Shihao Chen, Jia Qu, Qinmei Wang, Ahmed Elsheikh, Fangjun Bao

School of Health Professions

Background: This retrospective study aimed to evaluate the efficacy of transepithelial accelerated corneal cross-linking (transEpi ACXL) when applied separately or combined with phototherapeutic keratectomy (transPTK ACXL) in keratoconic eyes using biomechanical parameters. Methods: The study included eyes with progressive keratoconus treated with either continuous transEpi ACXL or transPTK ACXL with 6 months follow-up. The following parameters were assessed preoperatively and 6 months postoperatively: biomechanically corrected intraocular pressure (bIOP), maximum and mean keratometry (K _max and K _m), minimum and central corneal thickness (MCT and CCT), corneal coma, best-corrected visual acuity (BCVA), deformation amplitude ratio at 2 mm nasal/temporal (DAR2), …

Development, Performance Analysis And Application Of Polymer Inclusion Membranes: A Critical Review, Shayan Abrishami, Mahsa Golmohammadi, Matthew Myers, Masoumeh Zargar, Antonia Pérez De Los Ríos, Francisco José Hernández-Fernández, Amir Razmjou

Research outputs 2022 to 2026

Polymer Inclusion Membranes (PIMs) have emerged as sustainable separation platforms that integrate carrier-mediated selectivity within stable polymeric matrices, eliminating drawbacks of conventional solvent extraction such as solvent loss and emulsion formation. This review examines the fundamental principles, recent developments, and performance characteristics of PIMs, emphasizing design, fabrication, and operational optimization. The three essential components, base polymers, plasticizers, and carriers are systematically analysed alongside their synergistic effects on membrane stability, selectivity, and transport efficiency. Emerging materials including ionic liquids and deep eutectic solvents as dual-function plasticizers/carriers receive particular attention. Preparation methods are critically evaluated, including solution casting, phase inversion, and thermal …

Impact Of Plasma Ptau181 Levels On Clinician Diagnostic Confidence And Management In Memory And Cognition Clinics: A Multi-Site Before-And-After Study, Johannes C. Michaelian, Azadeh Feizpour, James C. Vickers, Jane E. Alty, Jessica M. Collins, Vincent Doré, Catriona Ireland, Anna E. King, Ralph N. Martins, Michael Woodward, Sharon L. Naismith, Christopher C. Rowe

Research outputs 2022 to 2026

Introduction: Recent advances allow blood tests to detect key proteins linked to Alzheimer's disease (AD). Methods: In this before-and-after study across three Australian memory and cognition clinics, we evaluated the impact on clinicians' diagnostic confidence and management following disclosure of routine patients' AD probability, using predefined plasma phosphorylated tau 181 (pTau181) thresholds set at 90% sensitivity and 90% specificity for amyloid-beta (Aβ) positron emission tomography (PET) positivity. Results: One hundred thirteen participants (mean age: 71.2 ± 8.4; mean Mini-Mental State Examination score: 27.7 ± 2.5) with dementia (n = 17, 15.0%), mild cognitive impairment (n = 48, 42.5%), and subjective …

Dynamic Knowledge Practices In Tourism Village Development: An Activity Theory Perspective, Xianyang Hu, Jie Chen, Songshan (Sam) Huang

Research outputs 2022 to 2026

This study investigates why tourism village development models often fail to replicate success despite cultural and geographic similarities. Using activity theory and knowledge management concepts, we analyze two adjacent Chinese villages to trace explicit knowledge flow and examine disrupted tacit and indigenous knowledge practices. Findings show that while surface-level knowledge transfer occurs, contradictions within activity system elements, especially the marginalization of indigenous knowledge and community capacity, hinder effective knowledge application. Knowledge flow is inherently nonlinear and deeply context-dependent. We develop a comparative activity system model that highlights how success hinges less on knowledge transfer and more on the integration of …

Overservice Backfires: The Impact Of High Robot Attentiveness On Tourists' Discontinuous Usage Intentions, Jinwei Wang, Yingzong Tang, Xin Chen, Songshan (Sam) Huang

Research outputs 2022 to 2026

AI-powered robots can meet both functional and emotional consumer service needs through proactive engagement. Yet, excessive attentiveness may produce unintended negative outcomes. Drawing on conservation of resources theory, this research employs four studies and a single-paper meta-analysis to investigate how highly (vs. moderately) attentive robotic service influences tourists' intentions to discontinue use. Results show that highly attentive robotic service increases discontinuous usage intentions, and this effect unfolds sequentially through perceived threat to freedom and emotional exhaustion. Furthermore, information sensitivity and technology anxiety moderate the relationship between robotic attentiveness and discontinuous usage intentions. These findings offer strategic insights for tourism practitioners …

3-Deoxyanthocyanidins Inhibit Β-Amyloid Aggregation, Toxicity, And Mitochondrial Dysfunction: Evidence From Mc-65 Cells And Molecular Dynamics Simulations, Rasheed A. Abdulraheem, Ammar U. Danazumi, Philipp Nitschke, Luke Gray Whiley, Abdulrahman Ibrahim Tudu, Ranil Coorey, Zhoyu Li, Prashant Bharadwaj, Vijay Jayasena, Stuart K. Johnson, Ralph N. Martins, W. M.A.D.Binosha Fernando

Research outputs 2022 to 2026

Accumulation of amyloid-beta (Aβ42) senile plaques in the brain is a hallmark of Alzheimer's disease (AD). Although some drug have been approvaled recently, none has demonstrated robust disease-modifying outcome. The 3-deoxyanthocyanidins (3-DXA) and their derivatives represent a more stable class of polyphenols, present at uniquely high concentrations in sorghum grains. Although 3-DXA exhibit strong potential to modulate protein aggregation processes, their effects on AD pathology remain unexplored. In this study, we investigated the inhibitory effects of three 3-DXA derivatives, apigeninidin chloride (AC), luteolinidin chloride (LC), and 7-methoxy apigeninidin (7-MAC), on Aβ42 aggregation and associated neurotoxicity. Thioflavin T fluorescence assay was …

Rethinking Artifact Evaluation For Software Engineering In The Age Of Generative Ai, Christoph Treude, Christopher M. Poskitt, Rashina Hoda

Research Collection School Of Computing and Information Systems

Peer review in software engineering research operates under tight time constraints, while generative AI has substantially reduced the human effort required to produce polished research narratives. Reviewer attention is often spent on aspects of submissions such as writing quality or literature positioning that have become relatively less effort-intensive to address, rather than on evaluating the scientific substance of a paper. At the same time, assessing whether methods are implemented correctly, analyses are sound, and claims are supported by evidence remains effort-intensive and dependent on human expertise. In software engineering research, this substance is frequently embodied in artifacts, including code, data, …

Additive Manufacturing Of Ti-Ni Based Ternary Shape Memory Alloys, Yitao Chen, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Metal additive manufacturing has become a powerful tool to develop customized metal alloys and to discover more advanced properties for novel extended applications. Ti-Ni based shape memory alloy is a group of intriguing smart functional materials, and adding a small amount of a third element can promote and induce more attractive functions. Due to the difficulty in traditional processing and the unique feature of material flexibility of in-situ alloying in additive manufacturing processes, not only Ti-Ni binary shape memory alloys but also Ti-Ni-X ternary shape memory alloys can be developed, manufactured, and investigated in-depth by additive manufacturing. This paper provides …

Advancing Fish Tissue Reference Material Development For Ag Nanoparticles Through A Perfusion Approach, Nathaniel J. Clark, Robert Clough, Adam Laycock, Rachel Smith, Richard D. Handy

School of Biological and Marine Sciences

There is a regulatory need for reliable methods to quantify nanoparticles in biological samples for the hazard assessment and bioaccumulation potential of engineered nanomaterials (ENMs). Single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) is a promising technique, but its application is hindered by the lack of validated sample preparation procedures (e.g., solubilisation) and suitable biological reference materials. This study aimed to develop an in-house biological reference material for ENMs to support analytical method validation. Silver nanoparticles (Ag NPs) were introduced into rainbow trout via cardiac perfusion, with the gills and liver collected as target tissues. Tissues were homogenised using a …

Available Space… The Final Frontier An Empirical Analysis Of The Heterogeneous Regulatory Burdens That Oversee Private Schools Within States With School Choice Policies, Patrick J. Wolf, Colyn Ritter, Misty Gallo

Education Reform Faculty and Graduate Students Publications

Using administrative data available from a variety of public sources, our research team examined the ways in which state and local regulatory burdens along with state political and economic factors work to encourage or depress the supply response of private school providers in the years following the adoption of school choice policies. We tracked counts of private schools using NCES and state departments of education at baseline year 1 of program implementation and a second outcome variable measuring the change from baseline to the current year (2024). We estimate the effect of state political and socioeconomic controls, two regulatory and …

Sensitivity And Concordance Study Of An Open Source Epid-Based Linear Accelerator Test Suite, Lana C Critchfield, Cory S Knill, Ellie Durussel, Justin K Mikell, Michael Barnes, Michael Pillainayagam, William P Donahue, Seng Boh Lim, John J Demarco, Mario Perez, Nilendu Gupta, Hania Al-Hallaq, Richard A Popple, Jim Irrer, Jean M Moran

2020-Current year OA Pubs

BACKGROUND: Electronic portal imaging devices (EPIDs) enhance linear accelerator (linac) quality assurance (QA) efficiency but are not universally used beyond patient-specific IMRT QA. A multi-institutional Consortium seeks to standardize linac QA utilizing an EPID-based test suite.

PURPOSE: This study evaluates the sensitivity of a test suite to intentional linac and plan errors and the concordance with linac fluctuations over time.

METHODS: Baseline and error-introduced tests were performed on a Varian TrueBeam and Clinac. Evaluated parameters included enhanced dynamic wedge factors (EDW) (6MV), central axis dose (6MV, 6MV FFF, 16MV), focal spot alignment and beam symmetry (6MV, 16MV), dose rate-gantry speed …

Sialidosis Type I: How To Alleviate Disabling Myoclonic Seizures? - A Multicenter Analysis Of Eight Cases And Review Of The Literature, Janina Gburek-Augustat, Shao Ching Tu, Marwan Shinawi, Isabel Alfradique-Dunham, Manouela Valtcheva, Et Al.

2020-Current year OA Pubs

OBJECTIVE: Sialidosis type I (ST-1) is an autosomal-recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic-clonic seizures (BTCS), and distinctive ophthalmological findings. Given the lack of curative options, in this study, we investigated symptomatic treatment strategies, with a particular focus on the efficacy of antiseizure medications (ASMs).

METHODS: We describe the clinical course of a patient followed from diagnosis to 18 years of age, and review seven additional cases from our cohort. In parallel, we conducted a narrative review of the literature (PubMed, January …

Use Of Inverse Probability Weighting In Cardiovascular Surgical Outcomes Research: Principles, Limitations, And Recommendations, Zhongjian Liu, Wei-Guo Ma, Lei Liu, Prashanth Vallabhajosyula, Haibo Wang

2020-Current year OA Pubs

This statistical primer presents a comprehensive introduction to the use of inverse probability of treatment weighting (IPTW), a method for rebalancing group confounders at baseline in cardiovascular surgical outcomes research. We leveraged a retrospective study comparing the outcomes of 2 different surgical approaches to aortic arch pathology to illustrate the essential aspects of performing IPTW, including basic theories, application, extreme weights, underestimated variance, heterogeneity of treatment effect, and multicollinearity. The limitations of IPTW were discussed with examples of solutions. Ten practical recommendations are made on avoiding the pitfalls in the use of IPTW. Proper use of IPTW may effectively reduce …

Exploring Nurses' Documentation Prioritization Strategies To Alleviate Ehr Documentation Burden: A Phenomenological Study, Rosemary Mugoya, Jennifer Thate, Fan Hao, Sarah C Rossetti, Po-Yin Yen

2020-Current year OA Pubs

OBJECTIVE: This study aims to understand how inpatient nurses determine and prioritize necessary documentation within the context of the Excessive Documentation Burden (ExDocBurden) in Electronic Health Records (EHRs).

METHODOLOGY: A phenomenological approach was used to explore inpatient nurses' lived experiences of prioritizing EHR documentation. Interpretive phenomenology guided the study design, focusing on how nurses prioritize documentation. Purposive sampling recruited 14 registered nurses (RNs) from acute and critical care settings. Data was collected through semi-structured interviews and analyzed using Colaizzi's 7-step and Smith's Interpretive Phenomenology Analysis.

RESULTS: Five themes emerged: (1) Advocating for Quality Patient Care Environment and Patient Needs, (2) …

Macroprudential Easing Measures In The Context Of Contractionary Monetary Policy: The Case Of Brazil In 2014, Marcos Antonio Paliari, Marcos Roberto Vasconcelos

Journal of Banking and Financial Economics

This paper evaluates the effects of a macroprudential policy of regulatory easing implemented amidst a contractionary monetary policy in Brazil. The intervention, carried out by the Central Bank in the third quarter of 2014, relaxed reserve requirements on time deposits to stimulate bank credit for vehicle financing. Using a Difference-in-Differences approach with fixed effects by credit modality and month, the analysis is based on monthly disbursement data for consumer loans from 2011 to 2018. Twelve rolling monthly windows are used to capture the dynamic evolution of the policy’s effects. Results based on a synthetic control group indicate statistically significant and …

Neuropsychiatric Symptoms Mimicking Dementia In A Patient Treated With Imatinib, Ashley Jones, Samuele Bonomi, Keith E Stockerl-Goldstein, Randall J Bateman

2020-Current year OA Pubs

Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations. He was investigated for dementia and psychiatric disorders but ultimately improved only after discontinuing imatinib. His decompensation years after therapy start, followed by complete and rapid remission, is atypical. We also review the most recent neurobiological findings on the role of tyrosine kinase alterations in dementia and their importance for mood regulation.

Acute Myocardial Infarction In Medicare Beneficiaries During And After The Covid-19 Pandemic, Jonah M Graves, R J Waken, Fengxian Wang, Rishi K Wadhera, Jose F Figueroa, E John Orav, Osvaldo J Laurido-Soto, Karen E Joynt Maddox

2020-Current year OA Pubs

IMPORTANCE: During early months of the COVID-19 pandemic, presentations for acute myocardial infarction (AMI) declined significantly, and outcomes worsened. However, the full extent and long-term sequelae of changes in AMI epidemiology during the pandemic remain uncertain, as does whether these patterns differed by rurality.

OBJECTIVE: To describe the epidemiology of AMI-related hospitalizations, interventions, and outcomes among Medicare beneficiaries throughout the COVID-19 pandemic, focusing on differences in urban and rural populations.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study included all Medicare fee-for-service beneficiaries with AMI between January 1, 2018, and December 31, 2023, in the analysis. Data were analyzed from …