Digital Commons Network^™

Modulatory Effects Of Garlic Nanoparticles On Cell Cycle Progression And Apoptosis In N-Nitrosodiethylamine-Induced Hepatocarcinoma In Rats, Asmaa A. M. Elwakil, Omayma A. R. Abo Zaid, Mohamed K. Mahfouz

Al-Farahidi Biomedical Journal

Background: Hepatocellular carcinoma (HCC) is considered a major cause of cancer-related mortality worldwide, which is resistant to several anticancer treatments. Associated with oxidative stress and reduced apoptotic regulation. Garlic displays powerful antioxidant effects and anti-tumor potential. In this study, we investigated the chemo preventive and therapeutic effectiveness of a novel garlic/ZnO/CTAB nanoparticles against diethyl nitrosamine (DEN)-induced hepatocarcinoma, focusing on their influence on cell cycle dynamics and apoptosis. Methods: Sixty male Wistar rats were divided into six groups: normal control, garlic nanoparticles normal-treated, DEN control, DEN + garlic nanoparticle protected, DEN + garlic nanoparticle treated, and DEN + doxorubicin treated as …

Gc-Ms Analysis Of Bioactive Components From Syzygium Aromaticum And Its Inhibition To Pathogenic Staphylococcus Sciuri Obtained From Aquatic Sources, Seham Abdel-Shafi, Mostafa I. Abdelglil, Mohamed F Ghaly, Saida Amer, Sobhy El Sawy Elsilk, Maysa M. Mohamed, Khaled Ali

Al-Farahidi Biomedical Journal

Antibiotic-resistant pathogenic microorganisms contaminate aquatic habitats. To prevent harmful bacteria isolated from pond and sewage water, this study assessed the green manufacturing of nanoparticles. A bioactive natural extract of Syzygium aromaticum inhibits the growth of bacteria in vitro. This study involved the isolation, purification, and identification of harmful microorganisms from aquatic sources. Traditional methods of identifying bacteria include Gram staining, bacterial cell morphology, colony shape, and biochemical assays, which are verified by 16S rRNA. The agar diffusion method is used to determine the minimum inhibitory concentration (MIC) of Syzygium aromaticum (cloves) on isolated samples. Cloves were used to biosynthesize …

Pyrimidine Scaffolds In Modern Medicinal Chemistry: A Review Of Biological Activities And Therapeutic Potential, Mohamed Tamer, Wesam S. Shehab, Doaa A. Elsayed, Abd-Elnasser A. Mohamed, Ali M. Al-Erian, Mostafa I. Abdelglil, Maysa M. Mohamed

Al-Farahidi Biomedical Journal

Pyrimidine derivatives represent an important class of nitrogen-containing heterocycles that play a central role in medicinal chemistry due to their structural diversity and broad spectrum of biological activities. Compounds containing the pyrimidine nucleus have been widely reported to exhibit antibacterial, anticancer, anti-inflammatory, antiviral, antidiabetic, and neuroprotective properties. The versatility of the pyrimidine scaffold arises from its ability to accommodate various substitutions and fused ring systems, which enables the modulation of physicochemical and pharmacological properties. This review summarizes recent advances in the synthesis of pyrimidine and fused pyrimidine derivatives, highlighting representative synthetic strategies and modern methodologies. In addition, the major pharmacological …

Design And Theoretical Evaluation Of Dihydropyrido[2,3-D]Pyrimidine Derivatives Synthesized Via Tio2 Nano Catalysis For Antidepressant Activity, Doaa A. Elsayed, Mostafa I. Abdelglil, Omar Metwally

Al-Farahidi Biomedical Journal

Nowadays, depression is a severe neuropsychiatric disorder affecting millions of people worldwide and has profound impacts on individuals, the economy, and society. Due to several limitations of currently available antidepressant drugs, including delayed onset of action, limited efficacy, and various side effects, there is a continuing need for the development of innovative, effective, and safer therapeutic agents. In this context, the present work describes a green and sustainable approach for the synthesis of dihydropyrido[2,3-d]pyrimidine derivatives using TiO₂ nanoparticles as an efficient and reusable catalytic system. The one-pot multicomponent reaction was carried out under mild conditions and demonstrated several advantages …

Effect Of Different Pellet Binders On Palm Kernel On Growth Performance And Nutrient Digestibility In Broiler Chicken, Nuun Marfuah, Burhanudin Sundu, Rusdi Rusdi, Sugiarto Sugiarto

Jurnal Ilmu Ternak Universitas Padjadjaran

Feed plays a paramount role in supporting growth, metabolism, and production performance. Their high price encourages the utilization of inexpensive and alternative feed ingredients. PKM, one such feed ingredient, is produced by palm oil industries. However, there is still a very limited application because of its high crude fiber content, which needs processing technologies like pelletization with binder addition. Based on this background, this experiment has been conducted to study the effect of various types of natural and commercial binders in 15% PKM-based pellets on performance and nutrient digestibility of broilers. The study was done for five weeks using 150 …

Evaluating The Impact Of K135t Mutation On Malate Dehydrogenase Kinetic Activity, Emily Frost, Kaitlyn Mello

Undergraduate Research Symposium (2026- )

Malate Dehydrogenase (MDH) is a key protein in the citric acid cycle; its dysregulation can have catastrophic impacts, such as neurological and metabolic disorders, and various cancers. MDH catalyzes the reversible oxidation-reduction reaction between malate and oxaloacetate, also reducing NAD+ to NADH in the process. The citric acid cycle is one of the central metabolic pathways, connecting to other essential pathways, such as amino acid and fatty acid biosynthesis, highlighting the importance of understanding how MDH works. A key site in MDH is the flexible loop region (amino acids 119-137), responsible for substrate binding, catalysis, and orientation. The flexibility of …

Czts Nanoparticles As Cost Efficient Catalysts For Producing Green Hydrogen, Aidan Hau

Undergraduate Research Symposium (2026- )

Hydrogen gas is produced to be used as feedstock, fertilizer, and fuel. Traditional hydrogen production produces “gray hydrogen” in a process that uses and releases fossil fuels into the atmosphere. One way to produce “green” hydrogen is with renewable energy technologies that produce hydrogen gas using electrolysis without emitting fossil fuels. In electrolysis, the hydrogen atoms bonded to oxygen in a water molecule are split to produce hydrogen. A typical catalyst for this process would be a precious metal like palladium, which can be costly. In order to make green hydrogen production more affordable, an alternative catalyst composed of CZTS …

Characterizing The Macroinvertebrate Community In Crissy Lake, An Impounded Reach Of The Pomme De Terre River, Prior To Channel Modification, Max Lundgren

Undergraduate Research Symposium (2026- )

The aging Crissy Lake Dam, on the Pomme de Terre River in Morris, has altered natural stream flow and impeded upstream passage of several fish species since 1939. In late 2026 the Minnesota Department of Natural Resources will replace the dam with stone arch rapids and facilitate river channel formation upstream of the dam. In order to evaluate the river modification project, we characterized the macroinvertebrate community in Crissy Lake, the impoundment upstream of the dam before implementation of channel modification. In September 2025 we collected benthic macroinvertebrates from two sets of Ekman grab samples. We found 12 taxa (average …

(Dis)Orientation: Using Queer Phenomenology To Teach Positionality And The Positionality Statement, Grace Mccleskey

Feminist Pedagogy

This paper offers a unit activity which is based on the integration of queer phenomenology in teaching positionality in undergraduate courses, exploring its potential as a feminist pedagogical tool for promoting self-reflection and critical engagement with identity. Drawing on Sara Ahmed's Queer Phenomenology, this approach invites students to understand how their embodied experiences of gender, race, and other social locations intersect with larger systems of power and privilege. I have built this unit around a series of creative exercises, including identity collages, story maps, and personal timelines, that help students reflect on their individual and collective experiences. By blending queer …

Image Processing Technique To Find The Burden Rock Velocity And Its Interdependency On Bench Blasting Parameters – A Case Study, Channabassamma N, Akhil Avchar, Sahas V Swamy, Vedala Rama Sastry, Hemant Agrawale

Journal of Sustainable Mining

In any rock engineering or excavation project, optimizing blast design is essential for controlling post-blast phenomena such as flyrock, burden throw, and burden rock velocity (BRV). This study investigates the dynamic response of BRV in bench blasting operations by employing a high-speed camera and ProAnalyst software to quantify rock displacement. The relationships between BRV and key blast parameters, number of holes (NH), explosive charge per hole (EPH), total explosive charge (TEC), stiffness ratio (K), and stemming ratio (STR), were analyzed to identify linear or non-linear trends. Non-linear trends, …

Appalachian Therapies, Emma Marie Wilson

Dr. Jay W. Boland Research Day

It is predicted that by 2050, deaths due to antibiotic resistance will supersede cancer and cardiovascular disease as the number one cause of death in the world. The present research aims to study the polymicrobial interactions of microbial communities in the Appalachian region. Microbial samples were obtained from mountains surrounding East Tennessee State University, isolated and screened against common human opportunistic bacteria. One particular bacterium, S1S4-10, was found to be antagonistic against Bacillus subtilis and created zones-of-inhibition on agar media. Reverse testing found that the B. subtilis did not have a counter inhibition against S1S4-10. Co-cultures found that S2S4-10 could …

One-Year Follow-Up Of A Frontal Sinus Mucocele Presenting With Ptosis, Zachary Shelton

Dr. Jay W. Boland Research Day

A mucocele is a benign mucus-filled cyst that forms after obstruction of paranasal sinus drainage. Enlargement can erode adjacent bone, producing mass effect symptoms such as congestion, headache, and proptosis. Rarely, orbital extension can lead to ptosis from compression of Cranial Nerve III (the oculomotor nerve). This report presents a one-year clinical and imaging follow-up in a 79-year-old male after surgical management of a frontal sinus mucocele presenting with ptosis. Initial examination demonstrated right-sided eyelid ptosis with mild restriction on right upward gaze. Prior MRI and CT displayed a right frontal sinus mucocele with sinus expansion encroaching on the right …

Cmsi Research In The News, China Maritime Studies Institute

CMSI Quarterly Review

No abstract provided.

Cmsi Quarterly (Spring 2026) Full Issue, China Maritime Studies Institute

CMSI Quarterly Review

Full issue of Issue 1 of the CMSI Quarterly Review.

Land Epistemic Ethic: Exploring The Complex Intersection Of Human Bodies, Land, And Identity In Middle Belt Nigeria Cosmologies, Fwangmun Oscar Danladi

International Journal on Responsibility

The Indigenous cosmologies of Nigeria’s Middle Belt emphasize the relationship between human bodies and the land, transcending Western epistemological binaries and revealing profound socio-religious insights into environmental responsibility. Practices such as the burial of newborns’ umbilical cords, often dismissed as animistic or fetishistic, embody a sacred connection to the land that emphasizes belonging rather than ownership. Using an autoethnographic approach, this study critically examines these cosmologies and identifies how the sacredness of land can serve as a repository of communal memory and potential. By reframing land not as a possession but as a relational entity, this research challenges dominant narratives …

College Going And The Class Of 2024, Tennessee. Higher Education Commission.

Miscellaneous Reports

No abstract provided.

Tennessee Education Lottery Scholarship Program 2025 Annual Report, Recipient Outcomes Through Fall 2024, Tennessee. Higher Education Commission.

Financial Aid Reports

No abstract provided.

A Black Feminist Perspective On The Role Of Community Engaged Pedagogy In Communication Education, Katrina Marie Overby, Nickesia S. Gordon

Feminist Pedagogy

As two Black feminist communication scholars, we reflect on the importance of intersectional and culturally responsive community engaged pedagogical practices in communication education. In this paper, we articulate the ways in which integrating community engaged pedagogical practices more intentionally in our curriculum, positions communication educators to participate in and contribute to advocacy based teaching that centralizes reflexivity, dialogue, critical literacy, and alliance building. Rooted in bell hooks’ theory of engaged pedagogy, our approach advocates for educators to articulate a pedagogy of Conscientizacao and to create curricula that teach us all to transgress.

Teaching Feminist Technoscience, Stephanie Hudson

Feminist Pedagogy

No abstract provided.

Critical Explorations: Using Feminist And Artful Inquiry In An Adolescent Literature Class, Emily L. Freeman

Feminist Pedagogy

Using feminist and artful inquiry in teacher education courses creates spaces of resistance to normative modes of sharing knowledge. The Critical Explorations project is the final assignment for a required young adult and adolescent literature course and requires that students engage in creative modes of expression when sharing their research. The teaching activity opens up new possibilities for engagement with texts and research questions that works to disrupt traditional English Language Arts assessments.

Engaging The World’S Cultures By Exploring Travel Possibilities: Overcoming Ethnocentrism To Demonstrate Cultural Awareness, Ashley D. Garcia, Daniel L. Foster

Feminist Pedagogy

This series of intercultural communication assignments was designed to assist students with the challenging transition from an ethnocentric (inflexible) mindset to an ethnorelative (flexible) one. At the beginning of the semester, students select a country and a corresponding international news source (online) to read throughout the semester. They complete several Engaging the World’s Cultures (EWC) assignments during the semester to accomplish two goals: to dive deep into the culture and to strengthen the uptake of an ethnorelative mindset when learning about a different culture. The information gathered through the EWC assignments is then compiled in a Travel Brochure at the …

The Citation Statement As Feminist Citational Praxis, Melissa Chomintra

Feminist Pedagogy

A key component of feminist information literacy and feminist research is the development of a citational praxis. One of the ways that students can foster their citational praxis is by writing a citation statement as part of their iterative research process. The purpose of this original teaching activity (OTA) is to teach students how to develop a citational praxis. The activity provides students with an introduction to citational praxis, the purpose of a citation statement, and the tools and strategies to implement it in their own research.

Mental Health Equity For Sexual And Gender Minority Students At A Rural University: Evidence From Etsu’S Healthy Minds Study, Richard Mutua Kilonzo

Dr. Jay W. Boland Research Day

Universities nationwide are reporting rising psychological distress among students, yet inequities in mental health for sexual and gender minority (SGM) students—those whose sexual orientation or gender identity differs from the majority—remain poorly understood in rural settings. This project examines whether SGM students at a rural public university in Central Appalachia experience greater mental health burden, distinct barriers to care, and less affirming service environments than their non-SGM peers, testing the hypothesis that SGM students have both higher symptom levels and greater unmet need for care. Guided by Minority Stress Theory (which links stigma-related stressors to health outcomes) and a social–ecological …

One Pot Conversion Of Cellulose To Dipropyl Ether And Dodecane, Katelyn Maness

Dr. Jay W. Boland Research Day

Cellulose is one of the most abundant renewable biopolymers, and its conversion into alkane hydrocarbons represents a critical step towards meeting increasing demands for sustainable fuel production. Traditional processes for this conversion require high hydrogen pressures and extreme temperatures, with molecular hydrogen often sourced from petroleum refining. Cellulose is typically broken down into smaller hydrocarbons, deoxygenated, and undergoes catalytic hydrogen transfer to form desirable products. This study, however, demonstrates an alternative pathway for conversion of microcrystalline cellulose (MCC) by employing metal oxides and hydrogen metal oxides (bronzes) under a modified ASTM E3417-24 acid hydrolysis protocol. Toluene allowed for extraction of …

Dental Hygiene Students’ Perceived Knowledge, Attitudes, And Confidence In Treating Patients With Sensory Processing Disorder, Hannah Dougherty

Dr. Jay W. Boland Research Day

Children with neurodevelopmental disorders, including Sensory Processing Disorder (SPD), may experience barriers to oral healthcare, including lack of dental provider knowledge, preparedness, and attitudes (Cermak et al., 2015). According to a qualitative study conducted by Dao et al. (2005), over 60% of dentists feel either poorly prepared or completely unprepared to safely and effectively treat patients with sensory disabilities. Additionally, a Qualtrics Likert-scale survey conducted by Lynch et al. (2023) studied the attitudes and behaviors of dental providers toward treating patients with special needs. Following analysis, the researchers determined the average dental provider’s confidence in treating patients with special needs …

Product Of Arachidonic Acid Oxidation Inhibits Neutrophil Migration By Forming The Inflammatory Substrate For Integrin Αmβ2, Jared Casteel

Dr. Jay W. Boland Research Day

Oxidation of arachidonic acid generates biologically active derivatives that play a critical role in shaping the inflammatory response. One such derivative, carboxypropylpyrrole (CPP), is a stable end-product of arachidonic acid oxidation that has been previously described and detected in inflamed tissues; however, its pathophysiological contribution to inflammation has not been investigated. CPP forms covalent adducts with the extracellular matrix and plasma proteins, altering their biochemical properties and receptor-binding characteristics. Here, we examined how CPP formation impacts neutrophil migration during acute inflammation. Using cell adhesion assays and biolayer interferometry, we identified integrins αMβ2 and αDβ2 as receptors for CPP-modified proteins. Among …

Family Structure And Elementary Students’ English Language Arts (Ela) Achievement: A Quantitative Case Study, Sophia Coulter

Dr. Jay W. Boland Research Day

There are many factors that affect a child’s literacy abilities, especially their family structure. Research shows that children in two-parent homes, particularly ones where parents are married and are the biological parents, have greater academic success. However, little research has examined how the number of caregivers, rather than household structure, relates to literacy achievement. This undergraduate honors thesis study seeks to address this gap by examining patterns in English Language Arts (ELA) standardized test scores of students in third grade and the number of adult caregivers in the home. Understanding these patterns may contribute to the ability of educators to …

Investigating Polymicrobial Interactions And Antibiotic Susceptibility Of Leclercia Pneumoniae, Amber Bhimani

Dr. Jay W. Boland Research Day

Leclercia pneumoniae is an emerging Gram-negative bacterium whose polymicrobial interactions and antimicrobial susceptibility patterns remain poorly characterized, limiting our understanding of its clinical behavior and treatment response. This study investigated the growth behavior and bacterial interactions of L. pneumoniae when co-cultured with Bacillus subtilis and Bacillus cereus to better understand competitive and inhibitory dynamics within microbial environments. It was hypothesized that co-culturing with Bacillus species would influence the growth of L. pneumoniae due to competitive interactions. Controlled in vitro experiments were conducted using monoculture and co-culture plating techniques to assess changes in colony morphology and potential zones of inhibition. Comparative …

The Proceedings Of The International Civil Aviation English Association (2024) Conference, Malila Prado, Jennifer Roberts, Robert Fowler Jr., Capt. R. Alejandro (Alex) Perez, Alice Perez, Meng Ye, Eric Friginal, Yadan Luo, Amber Wanwen Wang, Haryani Hamzah, Ramsey Ferrer

International Civil Aviation English Association

It is with great honor that we present you with the proceedings of ICAEA 2024, which took place in Hong Kong SAR, China. ICAEA 2024 was hosted by The Polytechnic University of Hong Kong, or simply PolyU, led by Professor Eric Friginal. The conference brought together academics and practitioners, all to discuss the advancements in aviation English all over the world.

The papers in this volume reflect part of the rich discussions of the conference. Themed Research and Development in Aviation Communications: Practical Applications in Training and Assessment, the conference showcased keynotes, presentations, and workshops about the evolving field of …

2024 Joint Annual Report On The Status Of Emergency Medical Services For Children, Tennessee. Department Of Health.

EMS and BLHCF Annual Report on Pediatric Emergency Care

No abstract provided.