Digital Commons Network^™

The Influence Of The Physical Work Environment On Retail Employees, Treasa Kearney, Joseph Coughlan, Aileen Kennedy

Articles

Despite repeated calls for research to explore the effects of the physical work environment on employees within the servicescape literature, gaps in knowledge remain. There is a need to understand the nature, influence and impact of environmental stimuli (e.g. music, colour) on employees. Extant research remains ambiguous on whether employees perceive individual stimuli within their work environment or perceive and interact with their physical work environment as a holistic experience. This study aims to explore the influence of environmental stimuli on employees within their physical work environment and the effect on their satisfaction and loyalty.

Peptidases Are Potential Targets Of Copper(Ii)-1,10-Phenanthroline-5,6-Dione Complex, A Promising And Potent New Drug Against Trichomonas Vaginalis, Graziela Vargas Rigo, Fernando Gomes Cardoso, Matheus Menonca Pereira, Michael Devereux, Malachy Mccann, Andre L.S. Santos, Tiana Tasca

Articles

Trichomonas vaginalis is responsible for 156 million new cases per year worldwide. When present asymptomatically, the parasite can lead to serious complications, such as development of cervical and prostate cancer. As infection increases the acquisition and transmission of HIV, the control of trichomoniasis represents an important niche for the discovery and development of new antiparasitic molecules. This urogenital parasite synthesizes several molecules that allow the establishment and pathogenesis of infection. Among them, peptidases occupy key roles as virulence factors, and the inhibition of these enzymes has become an important mechanism for modulating pathogenesis. Based on these premises, our group recently …

Silver(I) And Copper(Ii) 1,10-Phenanthroline-5,6-Dione Complexes As Promising Antivirulence Strategy Against Leishmania: Focus On Gp63 (Leishmanolysin), Simone S.C. Oliveira, Claudyane A. Correia, Vanessa S. Santos, Elaine F.F. Da Cunha, Alexandre A. De Castro, Teodorico C. Ramalho, Michael Devereux, Malachy Mccann, Marta H. Branquinha, Andre L.S. Santos

Articles

Leishmaniasis, caused by protozoa of the genus Leishmania, encompasses a group of neglected diseases with diverse clinical and epidemiological manifestations that can be fatal if not adequately and promptly managed/treated. The current chemotherapy options for this disease are expensive, require invasive administration and often lead to severe side effects. In this regard, our research group has previously reported the potent anti-Leishmania activity of two coordination compounds (complexes) derived from 1,10-phenanthroline-5,6-dione (phendione): [Cu(phendione)3 ].(ClO4 )2 .4H2O and [Ag(phendione)2 ].ClO4 . The present study aimed to evaluate the effects of these complexes on leishmanolysin (gp63), a virulence factor produced by all Leishmania …

Structural And Solution Speciation Studies On Selected [Cu(Nn)(Oo)] Complexes And An Investigation Of Their Biomimetic Activity, Ros Generation And Their Cytotoxicity In Normoxic, Hypoxic And Anoxic Environments In Mcf-7 Breast Cancer-Derived Cells, Hollie Jenkins

Articles

Reactive oxygen species(ROS) generation with subsequent DNA damage is one of the principle mechanisms of action assigned to copper-based anticancer complexes. The efficacy of this type of chemotherapeutic may be reduced in the low oxygen environment of tumours. In this study the cytotoxicity of three complexes, [Cu(dips)(phen)] (1), [Cu(ph)(phen)]·2H2O (2) and [Cu(ph)(bpy)]·H2O (3) (disp: 3,5-diisopropylsalicylate, phen: 1,10- phenanthroline, ph: phthalate, bpy: 2,2′-bipyridyl) were assessed for anticancer activity in the breast-cancer derived MCF-7 line under normoxic, hypoxic and anoxic conditions. In an immortalised keratinocyte HaCaT cell line, the cytotoxicity of complexes 2 and 3 was significantly reduced under both normoxic and …

Novel Therapeutic Approaches To Treat Brain Cancer Combining 3d Cell Culture Models, Cold Atmospheric Plasma And Airborne Acoustic, Janith Wanigasekara

Doctoral

Glioblastoma (GBM), an adult-type diffuse grade 4 glioma (IDH wild type), is the most prevalent, aggressive, fatal, highly vascularized, malignant primary brain tumour in adults with a poor prognosis. Despite existing therapies such as surgical resection, radiation therapy and chemotherapy such as temozolomide (TMZ), patient survival remains largely unchanged over the last three decades. There is an urgent need for novel and effective therapeutic strategies that can overcome drug resistance, cross the blood brain barrier, and minimise off-target side effects that can negatively impact a patient's quality of life. The high failure rate of clinical trials is due to inefficient …

Front Pages

American Indian Law Review

No abstract provided.

The Impact Of Climate Change On The Cultural Identity Of Indigenous Peoples And The Nation’S First “Climate Refugees”, Jordan K. Medaris

American Indian Law Review

No abstract provided.

Front Pages

American Indian Law Review

No abstract provided.

Pachamama Over People And Profit: A Case For Indigenous Ecology And Environmental Personhood, Hilda Loury

American Indian Law Review

No abstract provided.

When Reputation Is At Stake: Honour, Masculinity And Militarism In The Courts Martial Records Of The Marine Corps, 1755 – 1779, Lee-Jane Giles

School of Law, Humanities and Social Sciences Theses

This dissertation examines how the Marine Corps, as a newly formed permanent force, understood and embodied key social ideals such as honour and trustworthiness, respect and deference alongside martial behaviours. It uncovers and analyses the self-sanctioning nature of the marines’ officer corps to impose conforming behaviours during this key period in the Marine Corps’ development. However, this dissertation is equally interested in the non-commissioned and enlisted ranks, and their responses to the imposed conformity to these values. These early cases, linked to ideal behaviour, show a form of self-fashioning as the men of the Corps sought to form their identity …

George Morland (1763-1804) And The Representation Of Social Types, Heather Yeomans

School of Law, Humanities and Social Sciences Theses

George Morland was an eighteenth century artist, who was very popular not only during his lifetime, but in the following hundred years as well. He then fell out of popularity after changes in fashion and trends following the First World War. His paintings contain scenes of rural communities, families, animals, travellers, seaside communities as well as the slave trade, they cover a wide range of eighteenth century social types. Morland lived a ‘bohemian’ lifestyle which allowed him to get to know the people he depicted, living within the communities. His paintings have been analysed in detail in only a few …

Spectral Music; Why Create Compositions With Such A Limited Palette?, Iain Mason

School of Law, Humanities and Social Sciences Theses

Spectral Music: Why create compositions with such a limited palette? The question I am trying to answer is why the composers within the spectral movement of classical music created their compositions with such a limited and challenging palette of sounds. With the extreme wealth of musical knowledge and a rich tapestry of sounds and movements within the classical and contemporary musical world, why was it that the composers in question who I will be investigating; Gerard Grisey, Kaija Saaraiho, and James Tenney chose to write music with a limited palette of sounds? The music to generalise is made up from …

Assessing National Progress Of Mediterranean Countries In Shark Governance In The Context Of International Legal Obligations, Lydia Koehler

School of Law, Humanities and Social Sciences Theses

The work presented in this thesis introduces a conceptual framework for shark policy making against which national progress of Mediterranean coastal States in shark governance was assessed. A detailed assessment strategy was developed based on three distinct constructs, namely political commitment, research, and implementation effort. Based on multiple data sources (national reports under relevant conventions; policy documents; national legislation; online databases; scientific literature; and survey questionnaires to relevant government bodies, non-governmental organisations (NGOs), and national experts, designed as part of this assessment), individual differences between countries were determined and evaluated within the context of legal requirements under international and regional …

Trial By Jury And English Political Radicalism C.1792 – 1825, Richard John Marshall

School of Law, Humanities and Social Sciences Theses

This thesis explores the jury trial in English radical thinking, politics and political culture during the age of revolution. Its significance for radicals and the wider political nation has been underappreciated by scholars, as the ballast stabilising the British constitution and polity. I argue that juries served as a counterweight to repression and surrogate site of power for the underrepresented middling sorts: as jurors checking the power and social dominance of corrupt elites. Radicals recognised the power inherent in independent juries, campaigning to defend their verdicts and bolster their powers. The jury played a critical role in the rhetoric of …

Colorectal Surveillance Outcomes From An Institutional Longitudinal Cohort Of Lynch Syndrome Carriers, Gabriel Del Carmen, Laura Reyes-Uribe, Daniel Goyco, Kyera Evans, Charles M Bowen, Jennifer L Kinnison, Valerie O Sepeda, Diane M Weber, Julie Moskowitz, Maureen E Mork, Selvi Thirumurthi, Patrick M Lynch, Miguel A Rodriguez-Bigas, Melissa W Taggart, Y Nancy You, Eduardo Vilar

Faculty, Staff and Student Publications

OBJECTIVE: Lynch Syndrome (LS) carriers have a significantly increased risk of developing colorectal cancer (CRC) during their lifetimes. Further stratification of this patient population may help in identifying additional risk factors that predispose to colorectal carcinogenesis. In most LS patients CRC may arise from adenomas, although an alternative non-polypoid carcinogenesis pathway has been proposed for

DESIGN: We collected demographics, genetic, colonoscopy, and pathology results from a total of 163 LS carriers who obtained regular screening care at MD Anderson Cancer Center. Data were extracted from the electronic health records into a REDCap database for analysis. Logistic regressions were performed to …

Artificial Intelligence In Dentistry: A Bibliometric Analysis From 2000 To 2023, Xiujie Wen, Bo Xie, Dan Xu, Xuqiang Zou, Xuelian Peng, Mingjie Lu

Journal of Dental Sciences

Abstract Background/purpose Artificial intelligence (AI) is reshaping clinical practice in dentistry. This study aims to provide a comprehensive overview of global trends and research hotspots on the application of AI to dentistry. Materials and methods Studies on AI in dentistry published between 2000 and 2023 were retrieved from the Web of Science Core Collection. Bibliometric parameters were extracted and bibliometric analysis was conducted using VOSviewer, Pajek, and CiteSpace software. Results A total of 651 publications were identified, 88.7 % of which were published after 2019. Publications originating from the United States and China accounted for 34.5 % of the total. …

Gender Violence As Legacy: To Imagine New Approaches, Deborah M. Weissman

Faculty Publications

This essay considers gender violence as a consequence of systemic problems rooted in patriarchal structures, transacted through poverty and inequality, and embedded in a historically conditioned political economy. It is informed by the scholarship that propounds the need to develop community responses independent of the carceral system as a means to address the systemic source factors that contribute to Intimate Partner Violence (“IPV”), with attention to restorative and transformative justice approaches (RJ/TJ). This essay advances anti-violence scholarship to suggest the need to reconceptualize gender discrimination, poverty, and inequality as cause and consequence of social ills, and, moreover, to contribute to …

The Fraternity Of Legal Style, Alexa Z. Chew

Faculty Publications

This article reports the findings of an empirical study of writing experts mentioned in popular legal style books. The study shows that these experts are overwhelmingly men. This study complements the many other studies showing that gender and racial bias exists throughout the legal profession, but it focuses on one area that has not yet been examined: bias in books that give writing advice to lawyers. I call these books “legal style books.” The area of legal writing advice books is admittedly niche. However, it is worth studying because writing is central to lawyering.

A License To Play: Regulating Location-Based Augmented Reality Gameplay On Public Property, Kate Johnson, Evan Ringel, Amanda Reid

Faculty Publications

This novel research sits at the intersection of augmented reality gameplay and government licenses for use of public property. Governments have long used licensing schema to assure public safety and order. Augmented reality gameplay on public lands presents a new, contested use of public property. Under our proposed licensing scheme, those wishing to engage in location-based augmented reality (LoBAR) gameplay on public lands would need a license. This proposal is akin to how governments—federal, state, and municipal—have authorized permit schema for use of public property, including rock climbing, geocaching, street performing, and film photography. Our Article offers sample legislation for …

Critical Legal Research, Artificial Intelligence, And Systemic Racism: Teaching With Jim Crow Text-Mining, Ellie Campbell

Faculty Publications

On the Books: Jim Crow and Algorithms of Existence is a text-mining project undertaken by University of North Carolina–Chapel Hill libraries to identify racially based laws passed in the state between 1865 and 1967. In the fall 2022, I used the On the Books project to teach a module in my Advanced Legal Research class on critical legal research and artificial intelligence and legal analytics. This article examines the benefits of those modules for teaching critical thinking about legal research structures and legacies of racism in the American legal system.

Pitfalls Of Progressive Prosecution, Carissa Byrne Hessick

Faculty Publications

This Essay examines the political vulnerabilities facing the progressive prosecution movement, arguing that two core features of its public brand—emphasizing a fundamental break from traditional prosecution and pledging to “do less” by shrinking the criminal justice footprint—have inadvertently exposed reform‑oriented prosecutors to intensified backlash. Drawing on recent examples, the Essay shows how framing progressive prosecution as radically different obscures the long-standing prosecutorial tools these offices still rely on, enabling critics to portray routine exercises of discretion as unprecedented or dangerous. It further explains how decarceral commitments make progressive prosecutors easy targets when crime or disorder rises, both because voters may …

Fake And Real People In Bankruptcy, Melissa B. Jacoby

Faculty Publications

This essay explores the bankruptcy system’s structural bias in favor of artificial persons—for-profit companies, non-profit enterprises, and municipalities given independent life by law—relative to humans. The favorable treatment extends to foundational issues such as the scope and timing of debt relief, the conditions to receiving any bankruptcy protections, and the flexibility to depart from the Bankruptcy Code by asserting that doing so will maximize economic value. The system’s bias also contributes to the “bad-apple-ing” of serious policy problems, running counter to other areas of law that have deemed harms like discrimination to be larger institutional phenomena rather than merely the …

Multibillion-Dollar Tax Questions, James Alm, Jay A. Soled, Kathleen Delaney Thomas

Faculty Publications

Tax compliance in the United States historically hovers in the 80 percent range, costing the nation approximately half a trillion dollars annually in uncollected tax revenue. To foster greater tax compliance, the Internal Revenue Service (IRS) should employ whatever tools are at its disposal. Standard deterrence theory argues that increasing the audit rate and imposing stiffer penalties would foster greater tax compliance. There are political headwinds, however, that strongly suggest that these approaches are not currently viable. Instead, there is a low-cost method that could yield greater tax compliance. Drawing on recent and compelling social science research, the IRS should …

Secondary Courses Taught By Secondary Faculty: A (Personal) Call To Fully Integrate Skills Faculty And Skills Courses Into The Law School Curriculum Ahead Of The Nextgen Bar Exam, Oscar J. Salinas

Faculty Publications

This essay contends that law schools must reconsider how they educate future lawyers by elevating practical skills and the faculty who teach them, especially as the NextGen bar exam shifts toward assessing real‑world lawyering competencies. Through a blend of analysis and personal narrative, the author demonstrates how the traditional casebook‑Socratic model narrows the definition of merit, sidelines students whose strengths are not centered on rapid oral performance, and reinforces a hierarchy that undervalues skills faculty—who are often women and people of color—despite their central role in preparing students for practice.

Tracing the expansion of experiential learning after the Carnegie Report, …

The Vertical Evolution And Horizontal Correlation Of Information Science Education Research In China, Siyu Chen, Xiaofeng Zhu, Xumu Jiang

Journal of Scientific Information Research

[Purpose/significance]The comprehensive and accurate visualization of the information science education research in our country will help clarify the research context and inspire future research.[Method/process] Based on the relevant literature on "information education" in the CNKI database from 1980 to 2022, from the high-frequency keywords of the literature, the evolutionary context and development direction of our country's information science education research hotspots were longitudinally studied; from the three levels of system including our county's information science reseanch subject and research authar, our country's information science research research subject and research auther, horizontally explored and analyzed the mutual influence and mutual connection …

Disciplines Different Of Fine-Grained Acknowledged Entity：A Case Of Doctoral Dissertations In Chinese Humanities And Social Sciences, Jiaxin He, Shijin Zhang, Jiayu Zheng, Xinlong Chu, Chengzhi Zhang

Journal of Scientific Information Research

[Purpose/significance]Thesis acknowledgment is a public text in which the authors express their gratitude to individuals and institutions those support their research. It is helpful to understand the individuals and institutions that play a role in the cultivation of doctoral candidate in different disciplines by extracting the entities of acknowledgment and comparing the distribution of the objects of acknowledgment in the dissertations of different disciplines.[Method/process]In this paper, we gained more than 60 000 Chinese doctoral dissertations acknowledgment of 21 humanities and social sciences disciplines, extracted acknowledged entities from acknowledgment, and constructed a fine-grained classification system of acknowledgment entities. The classification system …

Communication Scholarship And The Quest For Open Access, Preston Carmack, Michael R. Kearney, Abbey Mccann

Journal of the Association for Communication Administration

The advent of black, green, and gold open access publication models poses unique questions for scholars of communication. Plato’s (1956) classic critique of writing in the legend of Theuth and Thamus warned that the printed word “rolls about all over the place, falling into the hands of those who have no concern with it” (pp. 69–70). More than two 2 millennia later, scholars and administrators at all levels of the discipline face just such a phenomenon. As scholars of cyberspace debate whether “information wants to be free” (Levy, 2014), a communication perspective involves consideration of the importance of authorship and …

“A Cog In A Wheel That Gets It Done”: A Qualitative Study Of The Experiences Of Faculty Seeking Administrator Support, Lakesha Anderson, Mattea A. Garcia

Journal of the Association for Communication Administration

This qualitative study sought to determine the stressors that motivate faculty to seek administrator support and examined faculty experiences of administrator support. Participants were 27 full- and part-time faculty members who completed a seven-item online questionnaire. Findings show that many participants felt unsupported by their administrator while navigating the stressful situations for which they sought help. This lack of support led to negative departmental cultures and faculty feeling insecure, undervalued, and isolated. This study highlights the need for policies and practices designed to build relationships between faculty and administrators. Efforts to improve the faculty-–administrator relationship can lead to increased understanding, …

The Impact Of Student Motivation, Preparation, And Learned Helplessness On Undergraduate Students’ Communication With Advisors, Heather Carmack

Journal of the Association for Communication Administration

The purpose of this exploratory study was to examine communication factors that influence students’ academic advising appointments, including predictors of scheduling future advising appointments. Undergraduate students’ motivation and feelings of learned helplessness were related to their advising meeting preparation and their communication involvement during advising meetings. Students who reported high levels of motivation and low levels of learned helplessness were more likely to prepare for advising meetings and be communicative during meetings. Students with immediate advisors were more likely to communicate with their advisors during meetings. Advising meeting preparation, motivation, and learned helplessness were significant factors in future advising appointments.

Learning To Think Like A Leader, Mark Hickson Iii

Journal of the Association for Communication Administration

This is the second in a three-part series that the author has been working on. The first part was included in an earlier issue of this journal.