Digital Commons Network^™

Prevalence And Associations Of Dural Arteriovenous Fistulae In Cerebral Venous Thrombosis: Analysis Of Action-Cvt, Aaron Shoskes, Liqi Shu, Thanh N Nguyen, Mohamad Abdalkader, James Giles, Jordan Amar, James E Siegler, Nils Henninger, Marwa Elnazeir, Sami Al Kasab, Piers Klein, Mirjam R Heldner, Kateryna Antonenko, Marios Psychogios, David S Liebeskind, Thalia Field, Ava Liberman, Charles Esenwa, Alexis Simpkins, Grace Li, Jennifer Frontera, Lindsey Kuohn, Aaron Rothstein, Ossama Khazaal, Yasmin Aziz, Eva Mistry, Pooja Khatri, Setareh Salehi Omran, Adeel S Zubair, Richa Sharma, Robert M Starke, Jacques J Morcos, Jose G Romano, Shadi Yaghi, Negar Asdaghi

Faculty, Staff and Student Publications

No abstract provided.

More Than A Monolith: Three Essays On The Diverse Journey Of Immigrant Students And Their Postsecondary Outcomes, Rian Rinaldi Djita

Graduate Theses and Dissertations

For many years, the United States (U.S.) has been the country with the largest number of immigrants. As a result, policy about immigrant students’ success becomes crucial since it carries not only ethical implications but also economic and societal implications. While there have been other alternatives for students’ success, such as Career and Technical Education (CTE), undeniably, college is still seen as a common pathway to success (e.g., Choi, 2015; Heckman et al., 2018; Turner, 2004). Unfortunately, there are several gaps in the literature on immigrant students’ success and postsecondary outcomes. First, while there is an increasing number of immigrants …

The Expression Of Recombinant Cas9 Proteins In E. Coli Bl21(De3) Strains, Morgan Reese

Graduate Theses and Dissertations

Abstract Extensively used for genome editing, CRISPR-Cas9 is a relatively new tool that has made a major impact in the genomic engineering landscape. Due to this, the production of CRISPR proteins that are not commercially available can limit research applications. Here, we present methods for optimizing laboratory scale production of CRISPR proteins including Cas9. The method uses IPTG to induce gene expression of the specified Cas9 and nickel column purification to isolate proteins. CRISPR proteins are validated for purity by SDS-PAGE gel, western blot, and for activity by in vitro digestion. We thoroughly validate and compare the effectiveness of BL21(DE3) …

Temporal Trends And Dental Metric Variation In The Macaca Sylvanus Lineage, Cristina Stan

Graduate Theses and Dissertations

The extensive collection of fossil macaques from Europe, spanning from the Late Miocene to the Late Pleistocene period, is believed to be of the species Macaca sylvanus. However, there has been a prolonged discussion regarding the classification of these specimens into a single taxonomic group as the existing dental sample exhibits a large amount of morphological and metric variation. Specifically, researchers have attempted to identify multiple subspecies based on chronological data of the paleontological locality and, secondly, based on dental metric variation. In this study, I assess temporal trends in the fossil record of Macaca sylvanus and compare overall variation …

Hypertensive Disorders Of Pregnancy And Long-Term Maternal Cardiovascular And Metabolic Biomarkers, Ashley N Battarbee, Lisa Mele, Mark B Landon, Michael W Varner, Brian M Casey, Uma M Reddy, Ronald J Wapner, Dwight J Rouse, John M Thorp, Edward K Chien, George Saade, Alan M Peaceman, Sean C Blackwell

Faculty, Staff and Student Publications

Objective: This study aimed to measure the association between hypertensive disorders of pregnancy (HDP) and long-term maternal metabolic and cardiovascular biomarkers.

Study design: Follow-up study of patients who completed glucose tolerance testing 5 to 10 years after enrollment in a mild gestational diabetes mellitus (GDM) treatment trial or concurrent non-GDM cohort. Maternal serum insulin concentrations and cardiovascular markers VCAM-1, VEGF, CD40L, GDF-15, and ST-2 were measured, and insulinogenic index (IGI, pancreatic β-cell function) and 1/ homeostatic model assessment (insulin resistance) were calculated. Biomarkers were compared by presence of HDP (gestational hypertension or preeclampsia) during pregnancy. Multivariable linear regression estimated the …

A Word From The Writing Team (May 2024), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• Join Us for Our Virtual Writing Retreat on May 3rd
• Save the Date for the 16th Annual Jefferson Faculty Days: June 5th & 6th
• Scott Memorial Library Archive Renovations Are Done—Come See!
• Thomas Jefferson University Has Updated Its Mission Statement
• Publication Spotlight
• Jefferson's AI Library Guide is Available on the Library Website
• The OPWPC Canvas Page Offers Helpful Tools

Inviting The Public Into Wildlife Research: Does Participation In Research Projects That Facilitate Interactions With Local Species Change Feelings Of Connection?, Seth Gibbons

All Dissertations

For many reasons, humans are less connected to nature. Research shows that people who feel more connected to nature are more likely to have pro-environmental intentions. One possible way to strengthen the human-nature connection is to involve the public in wildlife research, exposing them to local wildlife in a way that highlights science. This dissertation investigates two such projects, the 2019 Clemson Barred Owl Project and the Trout in the Classroom (TIC) program, to understand the effects of interacting with local species through wildlife research.

Interviews were conducted with participants and the lead researcher of the Clemson Barred Owl Project …

Mesenchymal Stromal Cell Response To Degenerated Intervertebral Disc-Like Ph, Kyle Cannon

All Dissertations

Intervertebral disc degeneration (IVDD) has become increasingly prevalent and is a common contributing factor to low back pain. There are currently no clinical treatment options for IVDD that alleviate the symptoms of IVDD while simultaneously promoting repair of IVD tissue. One treatment option being explored is intradiscal administration of mesenchymal stromal cells (MSCs). However, the microenvironment of the degenerating IVD places significant stress on both native IVD cells and implanted cells. There are several questions that need to be addressed which may help further inform the development of efficacious intradiscal MSC therapies for IVDD. These questions include: 1) Do MSCs …

Development Of Earthquake Hazard Prediction Software For South Carolina And Its Applications, Vishnu Saketh Jella

All Dissertations

This dissertation presents the development of earthquake hazard generation software, CarolinaShake and CarolinaADRS, for the state of South Carolina and its applications in the field of earthquake engineering. South Carolina is a seismically active state in the eastern United States, and there is a need to accurately quantify the earthquake hazard and incorporate it into the design of infrastructure systems. To achieve this objective, the South Carolina Department of Transportation (SCDOT) is actively supporting the initiatives to update its seismic design policies and procedures of civil infrastructure systems. As part of those initiatives, first, CarolinaShake, a Windows-based graphical user interface …

Development And Application Of Discrete Element Models For Granular Materials - From Rigid Spheres To Complex-Shaped Flexible Particles With Breakage, Zakia Tasnim

All Dissertations

Granular materials, which can range from nanometers to centimeters, are widely encountered as particles or powders in nature and in engineered systems. Some examples of granular materials include sands, gravels, biomass feedstocks, rice grains, pharmaceutical pills, glass beads, and lunar or martian regolith simulants. The attributes of and the interactions between constituent particles dictate the bulk mechanical properties and behavior of granular materials. The discrete element method (DEM), a particle-based modeling technique, has become a useful numerical tool for modeling the bulk behavior (such as mechanical, flow, and breakage behavior) of granular materials, where interactions between the granular materials' individual …

The Impact Of Mixed-Reality Simulation On The Knowledge And Practice Of Collaboration Skills Of Preservice Special Education Teachers, Samantha Scott

All Dissertations

Collaboration is an essential skill for a special education teacher's (SETs) success in developing individualized education programs (IEPs) to ensure that students with disabilities have access to equal educational opportunities. Collaboration occurs when members of an inclusive learning community work together as equals to meet a student’s individual needs. Unfortunately, preservice SETs are often provided with little instruction during their coursework and are not given the opportunity to attend IEP meetings in field placements. Many teacher education programs provide only a select number of opportunities for preservice SETs to practice and apply collaboration skills, leaving teacher candidates feeling underprepared to …

Leaders In Science Education Communities, Jennifer Bateman

All Dissertations

This three paper dissertation investigates the role of the District Science Coordinator (DSC). Due to the lack of research, District Science Coordinators (DSCs) are frequently misidentified as Science Teacher Leaders (STLs). It is important to establish a clear distinction between the roles. This first paper explores the salient similarities and differences between STLs and DSCs, while also attending to their individual roles, responsibilities, and professional support.

This second paper examines how a synchronous, online professional learning (PL) experience resulted in the creation of a community of practice (CoP) among two different groups of participating district science coordinators (DSCs) and how …

Oscillations Of Capillary Surfaces With Volume And Edge Effects, Dingqian Ding

All Dissertations

Capillary surfaces are defined by an interface endowed with surface tension that is partially supported by a solid substrate and are susceptible to oscillations reflecting a balance between fluid inertia and the restorative force of surface tension. The wave dynamics strongly depend upon volume change within the domain and edge effects through the boundary conditions applied at the contact-line formed at the liquid-gas-solid interface, while the spatial wave structure conforms to the geometry of the capillary surface. This dissertation develops mathematical models to address these effects for several canonical capillary surfaces, which are organized into two parts that are focused …

Structure And Dynamics Of Complex Fluids Formed By Ionomers: Experimental-Computational Insight, Chathurika Kosgallana

All Dissertations

The current study focuses on understanding the effect of clustering on the structure, dynamics, and response of ionomers in melts and solutions using neutron scattering methods combined with atomistic large-scale molecular dynamics (MD) simulations.

Ionizable polymers are used in a wide range of applications, such as in clean energy and biotechnology, where ion transport is integral to the application. Ionizable groups drive cluster formation and often become the dominating force in determining the structure and dynamics of these polymers.

The work consists of five studies. The first study probes the structure of sulfonated polystyrene in toluene solutions tweaked by the …

Connecting Genotype And Phenotype: Investigating The Functional Morphology And Molecular Architecture That Influences Craniofacial Divergence Using Lake Malawi Cichlid Fishes, Leah Delorenzo

All Dissertations

Connecting genotype and phenotype to better understand how species evolve has been a goal of evolutionary developmental biologists over the last 50 years. This dissertation aims to connect genotype and phenotype of the craniofacial skeleton within the adaptive radiation of Lake Malawi cichlids to fortify our understanding of the functional, genetic, and epigenetic factors that contribute to craniofacial divergence. I start with a functional approach using 2D geometric morphometrics to assess craniofacial shape across the Lake Malawi cichlid radiation to bolster our knowledge of the bone phenotypes that are important to niche specialization and are functionally relevant. Next, I use …

Electrode Engineering For Enhanced Performance And Low-Cost Redox Flow Batteries, Abena Williams

All Dissertations

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Predictors Of Sexual Behaviors Of Launching Adults In A Post-Roe World, Brandon Hunter Gardenhire

Electronic Theses and Dissertations

Recent changes in abortion law created a need to study how these changes may affect the most at risk and sexually active community: launching adults. This study investigated if abortion attitude and political identity predict risky sexual behavior of launching adults, even in the presence of the reliable predictor of sexual attitudes. Forty-one unmarried launching adults (18-25) were recruited through snowballing and convenience sampling. Results revealed that abortion attitude was a significant predictor of risky sexual behavior (F(1,39) = 5.25, p < .05, ß = .462, R² = .119), but not while in the presence of sexual attitudes. There …

Cabinet-Level School Administrators Intragroup And Intergroup Identity And Positive Leader-Member Exchange Dynamics: A Single Case Study, Larry R. Berger

Electronic Theses and Dissertations

This qualitative case study explored the challenges faced by the cabinet-level administration of a South Texas K-12 public school district in navigating intragroup and intergroup identity dynamics, impacting leader-member exchange, follower obligation, organizational behavior, and citizenship. Poor integration led to silo mentalities due to a lack of communication skills and social identity awareness among leadership. The study explored the influence of leaders’ attitudes and behaviors on intergroup and intragroup identities by examining how positive leader-member exchange practices affected collective organizational behaviors. Employing the framework of social identity theory, this study contributed to understanding specific leadership domains and the effective motivation …

Teacher Attrition: A Quantitative Analysis Of Driving Factors And Potential Solutions Among Highly Qualified K-12 U.S. Public School Teachers, Shari Donch

Electronic Theses and Dissertations

A comprehensive analysis is necessary to determine the cause of and solutions for the rate of K12 teacher attrition in the United States. Researchers have sought to understand the root causes of attrition or the institutional factors that influence teachers to voluntarily change professions. The most frequently identified factors include the personal characteristics of these teachers, freedom of curriculum development, teacher autonomy, and resources such as salaries. Evidence shows that this attrition among highly qualified teachers is detrimental to the quality of education, particularly in terms of student outcomes, and substantiates that effective initiatives surrounding remediation of these factors are …

Education And Bingo Exercise: Pressure Injury Reduction In An Assisted Living Facility, Emmalee Holmes, Ashley Jaynes, Annah Khan, Caitlin Thornton, Brooke Waller

ELMSN E-Portfolio. A collection of Scholarly and Creative Works

No abstract provided.

Nurturing Respectful Maternity Care In Rural Kenya: Assessing The Impact Of Educational Interventions On Local Healthcare Workers, Jessie Chen, Jassmine Duong, Urangoo Matthews, Avery Rocha

ELMSN E-Portfolio. A collection of Scholarly and Creative Works

No abstract provided.

Health Of Indigenous Orphans And Carers In Perú: A Mixed Methods Case Study Of Hogar De Niñas Virgen De Fatima, Lee Fergusson, Javier Ortiz Cabrejos, Anna Bonshek, Aparna Datey

Journal of Contemplative and Holistic Education

The COVID-19 pandemic dealt a devastating blow to the social fabric of Perú, with the highest orphans per death (OPD) ratio of any country in Latin America. Therefore, 260,000 orphans now require care because of 216,000 parent, custodial grandparent, and caregiver deaths between 2020 and 2022. The purpose of this research is to examine whether the practice of Transcendental Meditation, an established technique for improving the mental and physical health of children, can reasonably be expected to alleviate the symptoms of trauma associated with this surge in orphanhood.

Adolescent indigenous female orphans and their carers at Hogar de Niñas Virgen …

As The Night Is Lit: The Nocturnal Urban Landscapes Of Childe Hassam., Diana M. Wilder

Electronic Theses and Dissertations

The scientific investigations into light that began with the Enlightenment garnered added information useful for artists. To depict the changes in light due to weather, time of day, and season more accurately, artists took the information reaped from studies of the refraction of light gained from Isaac Newton’s color theories. The new technological advances of gaslight and electric arc lighting also changed the way that light was represented on canvas. Artists were now able to paint in their ateliers due to modern lighting that would light up the rooms like the day. Some artists decided to explore the night and …

Predicting The Effects Of Precipitation On Groundwater Contamination Near Capped And Uncapped Coal Ash Storage Facilities In Louisville, Kentucky., Daryl Jialiang Chen

Electronic Theses and Dissertations

This study examines the impact of rainfall event characteristics and water table elevations on arsenic and boron contamination in groundwater near two coal ash ponds in Louisville, Kentucky. Utilizing data from 2011 to 2019, the research focuses on both capped and uncapped ponds at Mill Creek and Cane Run sites, employing Threshold Analysis, Regularized Discriminant Analysis (RDA) and Random Forest (RF) to assess contamination levels in groundwater. Analysis shows that capped ponds generally exhibit reduced arsenic levels, though variations exist depending on the contaminant and site. Key predictors such as maximum precipitation and river height were identified, highlighting their significant …

Anthropogenic Litter In Urban Waterways: An Analysis Of Litter, Urbanization, And The Emerging Role Of Citizen Science In Beargrass Creek, Louisville, Ky., Ella Swigler

Electronic Theses and Dissertations

This thesis addressed the ever growing presence and persistence of anthropogenic litter (AL) in urban waterways. AL has been studied in marine environments, but research gaps exist in riverine ecosystems. Most of the AL that reaches the Earth’s oceans is carried by urban rivers, so understanding the relationship between these waterways and AL is critical in effectively fighting AL accumulation, especially for legacy plastic pollutants. The study explored fifteen sites throughout Beargrass Creek and recorded the quantity and type of AL present throughout the summer and fall of 2023. The National Geographic Marine Debris Tracker App was employed to successfully …

Administrative Reliance, Haiyun Damon-Feng

Articles

Presidential regime change and the federal policy shifts that accompany it raise significant questions concerning continuity, stability, and governance in the administrative state. Presidential policymaking through the administrative state may generate serious reliance interests recognized under administrative law (what this Article calls “administrative reliance”), which agencies must consider prior to enacting policy change. Administrative reliance has developed into a robust form of judicial review over agency action. Administrative reliance has been invoked in highly politicized contexts, such as immigration law, to challenge a sitting administration’s termination of a prior administration’s policies. Despite its powerful and consequential effects, the doctrine of …

Adapting Language Development Research Paradigms To Online Testing: Data From Preferential Looking, Word Learning And Vocabulary Assessment In Toddlers, Delphine K.L. Nguyen, Nadine Fitzpatrick, Caroline Floccia

School of Psychology

During the recent pandemic, it became necessary to adapt lab-based studies to online experiments. To investigate the impact of online testing on the quality of data, we focus on three paradigms widely used in infant research: a word recognition task using the Intermodal Preferential Looking Paradigm, a word learning task using the Switch task, and a language assessment tool (WinG) where children identify a target word amongst a set of picture cards. Our results for synchronous and asynchronous studies provide support for the robustness of online testing. In Experiment 1, robust word recognition was found in 24-month-old toddlers. In Experiment …

Say Yes To Oral Care! A Quantitative Report On Oral Health And Education In The Unhoused Population, Kiana Correa, Sharon Lew, Brianna Satram, Ashika Singh

ELMSN E-Portfolio. A collection of Scholarly and Creative Works

No abstract provided.

Primary Focal Segmental Glomerulosclerosis In A Patient With Ankylosing Spondylitis: A Rare Presentation Requiring A Broad Differential In Nephrotic Syndrome., Pooya Zardoost, Sana Tyabuddin, Austin Cantu, Musa Abu-Jubara, Jackson Mittlesteadt, Henry Wehrum

Ambulatory and Primary Care Articles

Ankylosing spondylitis (AS) presents with renal failure and proteinuria in a minority of cases, usually due to secondary amyloidosis or IgA nephropathy. While focal segmental glomerulosclerosis (FSGS) is less common, it should still be in the differential regardless of the patient's clinical profile.

Ability Of Genomic Prediction To Bi-Parent-Derived Breeding Population Using Public Data For Soybean Oil And Protein Content, Chenhui Li, Qing Yang, Bingqiang Liu, Xiaolei Shi, Zhi Liu, Chunyan Yang, Tao Wang, Fuming Xiao, Mengchen Zhang, Ainong Shi, Long Yan

Horticulture Faculty Publications and Presentations

Genomic selection (GS) is a marker-based selection method used to improve the genetic gain of quantitative traits in plant breeding. A large number of breeding datasets are available in the soybean database, and the application of these public datasets in GS will improve breeding efficiency and reduce time and cost. However, the most important problem to be solved is how to improve the ability of across-population prediction. The objectives of this study were to perform genomic prediction (GP) and estimate the prediction ability (PA) for seed oil and protein contents in soybean using available public datasets to predict breeding populations …