Digital Commons Network^™

Treatment Modifications And Development For Mucopolysaccharidosis Type I, Sarah Hurt

Arts & Sciences Graduate Student Theses and Dissertations

Mucopolysaccharidosis type I (MPS I) is a pediatric lysosomal storage disorder caused by biallelic pathogenic variants in the α-L-iduronidase (IDUA) gene that lead to the loss of a functional form of IDUA enzyme. Loss of this necessary enzyme leads to pathogenic accumulation of glycosaminoglycans (GAG) in lysosomes, leading to cellular distention and dysfunction. IDUA is necessary in every cell of the body and, as a result, a loss of function leads to clinical manifestations of the disease such as developmental delay, cardiac dysfunction, bone disease (dysostosis multiplex), upper respiratory complications, and premature death. A range of severity occurs, with Hurler …

Pilots' Desire To Become Future Space Tourism Pilots: Polynomial Regression Using Response Surface Analysis, Robert A. Goehlich, Ralf Bebenroth

Publications

In this study, we investigated the impact of pilots’ motivation on their desire to be space tourism pilots or to remain in their current occupation (adherence). We analyzed the feedback obtained from a survey questionnaire on a sample consisting of 106 pilots with flying experience. In particular, we compared the pilots’ intrinsic and extrinsic motivations to investigate two outcomes: the desire to become future space pilots or to remain as air pilots. Applying the self-determination theory, we found that intrinsic motivation mattered more than extrinsic motivation. Furthermore, by applying response surface analysis as our statistical tool, it was revealed that …

What Do We Know About Hugging Face? A Systematic Literature Review And Quantitative Validation Of Qualitative Claims, Jason Jones, Wenxin Jiang, Nicholas Synovic, George K. Thiruvathukal, James C. Davis

Computer Science: Faculty Publications and Other Works

Background: Collaborative Software Package Registries (SPRs) are an integral part of the software supply chain. Much engineering work synthesizes SPR package into applications. Prior research has examined SPRs for traditional software, such as NPM (JavaScript) and PyPI (Python). Pre-Trained Model (PTM) Registries are an emerging class of SPR of increasing importance, because they support the deep learning supply chain.
Aims: Recent empirical research has examined PTM registries in ways such as vulnerabilities, reuse processes, and evolution. However, no existing research synthesizes them to provide a systematic understanding of the current knowledge. Some of the existing research includes qualitative …

Interpreting The Biological Effects Of Protons As A Function Of Physical Quantity: Linear Energy Transfer Or Microdosimetric Lineal Energy Spectrum?, Fada Guan, Lawrence Bronk, Matthew Kerr, Yuting Li, Leslie A Braby, Mary Sobieski, Xiaochun Wang, Xiaodong Zhang, Clifford Stephan, David R Grosshans, Radhe Mohan

Faculty, Staff and Student Publications

The choice of appropriate physical quantities to characterize the biological effects of ionizing radiation has evolved over time coupled with advances in scientific understanding. The basic hypothesis in radiation dosimetry is that the energy deposited by ionizing radiation initiates all the consequences of exposure in a biological sample (e.g., DNA damage, reproductive cell death). Physical quantities defined to characterize energy deposition have included dose, a measure of the mean energy imparted per unit mass of the target, and linear energy transfer (LET), a measure of the mean energy deposition per unit distance that charged particles traverse in a medium. The …

The Backrooms, Julianna C. Yachimowicz

Night Flight: Online Literary Journal

We follow Fin through his recovery after a nasty accident, but something just isn't right.

Volume 7, Issue 1, Full Issue

Society for American Sign Language Journal

No abstract provided.

Enhanced Shoulder-Surfing Cued Recall Graphical Password System: Sequential Passpoint, Titus D. Fofung

Cybersecurity Graduate Research Symposium

During the past two decades, many graphical passwords have been used widely as an alternative to text-based passwords. However, most graphical password systems are plagued by shoulder-surfing problems, usability, and remembering capability. This study proposed a new graphical password called SPP (Sequential PassPoint), allowing users to remember three click-points on two images in specified order and image order. When the image order changes, the click order is reversed. Two decoy images for three random clicks were introduced to enhance the security of SPP. The proposed SPP system was validated both theoretically and empirically

Quantum Computing, Geopolitics, And Latin America, Heriberto Acosta-Maestre

Cybersecurity Graduate Research Symposium

No abstract provided.

Observations Of Co-Nest Building And Spawning In Native And Non-Native Chub Species (Nocomis Spp.) In The Swannanoa River, North Carolina, Patrick Ciccotto

Southeastern Fishes Council Proceedings

Co-nest building and spawning among individuals of the native population of River Chub (Nocomis micropogon) and among those of an introduced population of Bluehead Chub (N. leptocephalus) observed in the Swannanoa River (French Broad River basin) during Spring 2024 represents the first time such behaviors have been documented between two species of Nocomis. Observations of these behaviors are described and discussed in the context of potential hybridization and the impact of introduced Bluehead Chubs in the French Broad River basin.

Experimental Study To Assess The Role Of Environment And Device Type On The Success Of Social Engineering Attacks: The Case Of Judgment Errors, Tommy Pollock

Cybersecurity Graduate Research Symposium

No abstract provided.

Gas Chromatography-Mass Spectrometry (Gc-Ms), Computational Analysis, And In Vitro Effect Of Essential Oils From Two Aromatic Plants, Bubonium Graveolens And Launaea Arborescens Growing In Southwest Algeria Against Potato Cyst Nematodes, Souad Ziane, Chaouki Selles, Khaldun M. Al Azzam, Bounoua Nadia, Belal O. Al-Najjar, Ali Al-Samydai, Obada A. Sibai, El-Sayed Negim

Karbala International Journal of Modern Science

The study tested the nematicidal effects of essential oils from Bubonium graveolens and Launaea arborescens on the potato cyst nematode Globodera rostochiens. The chemical composition of the essential oils was analyzed using GC-MS. To determine the concentration that killed 50% of the nematode population (LC50), five concentrations of the essential oils were applied to the tested organisms. The effects of essential oils on the hatching of cyst nematode (Globodera rostochiensis sp.) eggs in vitro demonstrated a wide variety of effects ranging from no impact to mild, moderate, and strong effects, which increased dramatically with exposure duration and concentration. All the …

Broken Su(3) Description Of Energy Levels And Decay Properties In Gadolinium Isotopes (A=156-160), Fahmi Sh. Radhi, Amir Abdul Ameer Mohammed Ali Dr., Ali H. Al-Musawi

Karbala International Journal of Modern Science

This study presents an in-depth examination of the energy levels and decay properties of Gadolinium (Gd) isotopes with mass numbers (A=156-160), utilizing the Interacting Boson Model-1 (IBM-1) within a broken SU(3) symmetry framework. Through this approach, we systematically calculated and analyzed the energy spectra, B(E2) transition probabilities, quadrupole moments, and potential energy surface (PES) which provided valuable insights into the shape and collective behavior of nuclei, as well as the decay properties of the selected Gd isotopes. The broken SU(3) symmetries provide a good description to the isotopes under study. This comprehensive analysis enhances the understanding of the nuclear structure …

Development Of A Universal Cybersecurity Competency Framework For Organizational Users, Patricia Baker

Cybersecurity Graduate Research Symposium

No abstract provided.

Development Of A Universal Cybersecurity Competency Framework For Organizational Users, Patricia Baker

Cybersecurity Graduate Research Symposium

No abstract provided.

Assessing Organizational Investments In Cybersecurity And Financial Performance Before And After Data Breach Incidents Of Cloud Saas Platforms, Munther B. Ghazawneh

Cybersecurity Graduate Research Symposium

No abstract provided.

Using Ontological Methods To Compare Cybersecurity Maturity Model Certification 2.0 And Cobit 19, Aaron M. Ramey

Cybersecurity Graduate Research Symposium

No abstract provided.

Examining Consumers' Selective Information Privacy Disclosure Behaviors In An Organization's Secure E-Commerce Systems, Patrick I. Offor

Cybersecurity Graduate Research Symposium

No abstract provided.

Spartan Daily, October 23, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 163, Issue 26

Breathing Inequality? Income, Ethnicity And Pm2.5 Exposure In Bologna, Italy, Alessandra Drigo

Fondazione Eni Enrico Mattei Working Papers

This study addresses the presence of an environmental justice issue along the dimensions of income and ethnicity in the urban context of Bologna, Italy. Among other Italian cities, Bologna has historically had a left-leaning political tendency and has made considerable substantial efforts to address social issues extensively. This makes it a useful cross-section dataset links gridded PM2.5 concentration data at 0.01°x0.01° resolution with census demographic characteristics and income per capita information for the year 2011. This study presents two main findings. i) It confirms the existence of an environmental justice gap, which affects vulnerable segments of the population along both …

Role Of Spectroscopy For Real Time Monitoring And Control Of Continuous Bioprocesses, Anurag Rathore

Integrated Continuous Biomanufacturing VI

Please click Additional Files below to see the full abstract

Icb Risk Assessment: Case Studies In Practice (Roundtable Workshop), Gene Schaefer, Kelly Wiltberger

Integrated Continuous Biomanufacturing VI

Please click Additional Files below to see the full abstract

Researching Company & Industry Data, Sandra Teft

Handouts

This in-class assignment was designed to get students started on gathering data required for their MKT 351 project, Consumer Based Marketing Insights Report. The students were required to divide into evenly distributed groups (with my assistance) and work within the databases I demonstrated during class to find data. The students selected one student from each group to report their findings.

At Harvard Mgh’S Mouro Pinto Lab, Deploying Crispr In The Quest To Cure Huntington’S Disease, Kenneth P. Serbin Phd

At Risk for Huntington's Disease

No abstract provided.

Readiness Of Cybersecurity In The Usa Energy Industry, Aaron Cavanaugh

Dissertations and Theses

Cybersecurity Readiness shows an organizations ability of applicant and application to be able to fully utilize computing resources through behaviors (e.g., training employees), practices, and processes, while managing risk through efficient controls in order to prevent, detect, and respond to outage scenarios using audit and assessment techniques. An evaluation of cybersecurity readiness for the USA energy industry assists industry decision makers to comprehensively assess readiness gaps for prioritizing a risk-based cybersecurity implementation plan. There is a currently a lack of a Multi-Criteria Decision Model (MCDM) to assist decision makers to comprehensively assess Readiness of Cybersecurity in the USA Energy Industry. …

Engineering Students Discover Community And Sustainable Innovation In Costa Rica, University Of Dayton

Blog: The Dayton Engineer

First-year engineering students have the opportunity to participate in the Costa Rica Immersion Program with their classmates and professors during Spring Break.

The Lumberjack, October 23, 2024

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Professional Development: A Mixed Methods Study Of Masters Of Public Health Alumni, Orna Baron-Epel, Yana Douvdevany, Dana Ivancovsky-Wajcman, Paul Barach, Osnat Bashkin, Katarzyna Czabanowska, Keren Dopelt, Nadav Davidovitch, Szczepan Jakubowski, Fiona Macleod, Maureen Malowany, Leah Okenwa-Emegwa, Maya Peled-Raz, Shira Zelber-Sagi

College of Population Health Faculty Papers

INTRODUCTION: We examined the perceptions of the Master of Public Health (MPH) degree graduates regarding their personal competencies, job performance and professional development using a mixed method, explanatory sequential design.

METHODS: A cross-sectional, self-administered questionnaire of the Haifa School of Public Health alumni who graduated between 2005 and 2022 was disseminated to 849 graduates between March and June 2022, from which 127 responded (response rate: 14.90%). This was followed by 24 in-depth interviews with alumni from the same sample (conducted between November 2022 and March 2023).

RESULTS: The sample included 74.8% of females with a mean age of 40.7 years, …

Office Of Research, Economic Engagement And Outreach Update, October 23, 2024, Office Of Research, Economic Engagement And Outreach

Office of Research, Economic Engagement and Outreach

No abstract provided.

Antitrust Without Competition, Daniel Francis

Duke Law Journal

Competition is everywhere in antitrust. Courts, agencies, and scholars routinely insist that antitrust can, does, and should measure the legality of conduct by asking whether it has harmed or promoted “competition.” The idea that competition is, without further definition, a coherent value that can be increased or reduced—and used to guide the development and application of antitrust rules—has dominated doctrine for a century, and is deployed freely by judges, enforcers, and writers across the political spectrum.

This does more harm than good, and it should stop. There is no single value or quantity, in economics or antitrust law, that competition …

Relocating Justice, Ruhan Sidhu Nagra

Duke Law Journal

Managed retreat—the planned relocation of people facing imminent climate threats—is an inevitable part of future climate adaptation in the United States. Given that Black, Brown, and low-income communities are disproportionately vulnerable to climate hazards, managed retreat has significant justice implications. This Article explores what I call an apparent “justice paradox”—two “justice problems” with managed retreat that seem to point to opposite solutions. On the one hand, managed retreat can be inaccessible to marginalized communities, many of whom lack the resources to successfully navigate the relocation process. This justice problem suggests that decision-makers should prioritize managed retreat for marginalized communities since …