Digital Commons Network^™

Integrating Responsible And Ethical Conduct Of Research Into Cures: A Longitudinal Study Observing Professional Development Of Fellows Within The Ethics Network For Course-Based Opportunities In Undergraduate Research, Aimee Angelica Hernandez-Gaytan

Open Access Theses & Dissertations

No abstract provided.

Water Fluoridation: The Evidence Behind The Risk Of Fluoride Use, Margherita Fontana D.D.S., Ph.D., Carlos González-Cabezas D.D.S., M.S.D., Ph.D., Livia Tenuta D.D.S., M.Sc., Ph.D.

The Journal of the Michigan Dental Association

The debate surrounding fluoride use for caries control has intensified due to recent events, including a National Toxicology Program (NTP) report and a court ruling mandating EPA action on fluoride levels in tap water.

Despite concerns about fluoride's potential neurodevelopmental impact at high concentrations, current evidence shows no adverse effects at the recommended levels of 0.7 ppm in U.S. community water fluoridation programs. While studies in regions with endemic fluorosis suggest an association between high fluoride exposure and lower IQ, methodological limitations undermine causal conclusions.

Global and U.S. health authorities, including the WHO and ADA, reaffirm the safety and efficacy …

Enhancing The Utility Of Unmanned Autonomous Vehicles (Uavs) With Model-Based Systems Engineering (Mbse) And Modular Open Systems Approach (Mosa), Aimee Barraza

Open Access Theses & Dissertations

Unmanned Autonomous Vehicles (UAVs) have emerged as versatile tools with significant implications across various industries, particularly in defense. The technological advancements in UAVs have revolutionized military operations, surveillance, and reconnaissance capabilities. However, there exist challenges such as environmental factors affecting sensor and flight performance, limited battery life restricting flight durations, and payload capacity constraints impeding task efficiency.This paper delves into the importance of UAVs in different industries, specifically focusing on their pivotal role in the Department of Defense. It emphasizes the necessity of technological upgrades to overcome current challenges and proposes the adoption of a Modular and Open System Approach …

Optimization And Purification Of Magnesium Borides Fabricated By Combustion Synthesis And By High-Temperature Sintering, Miguel Joaquin Camarena

Open Access Theses & Dissertations

Hydrogen as a fuel provides several benefits over the use of fossil fuels; however, one challenge in utilizing hydrogen as an energy carrier revolves around its storage. Achieving sufficient volumetric hydrogen density in a storage solution will facilitate hydrogenâ??s adoption for use in both stationary and mobile applications. Solid-state hydrogen storage provides a promising pathway to solving this problem. However, the hydrogenation of these materials is characterized by slow kinetics and extreme thermodynamic conditions. Magnesium borohydride (Mg(BH4)2) is a promising material in hydrogen storage due to its reversible properties and a theoretical hydrogen capacity of 14.9 wt.%. To synthesize this …

Functionalized Carbon Quantum Dots: A Promising Nanomaterial For Investigating Their Potential In Neurodegenerative Disease Treatment, Sherin M. El Morsy

Open Access Theses & Dissertations

Neurodegenerative diseases such as Parkinson's Disease (PD), Alzheimer's Disease (AD), and Huntington's Disease (HD) remain incurable, despite extensive research into therapeutic development. In the United States of America, the annual cost of PD and AD in terms of patient care and lost productivity is approximately $200 billion. Consequently, there is a critical and unaddressed need for the development of innovative drugs and drug delivery systems that can decelerate, stop, or ideally reverse neurodegenerative diseases. The dissertation presented here focuses on devising strategies to target PD through multiple mechanisms, including the inhibition of protein aggregation and the reduction of oxidative stress. …

Synthesis Of Materials For Additive Manufacturing Of Enhanced Polymers And Textured Ceramics, Diana Fontes

Open Access Theses & Dissertations

This research will be divided into two sections. The first section investigates the development of textured Barium Titanate (BaTiO3) ceramics fabricated through Direct Ink Write Printing (DIW) integrated with Templated Grain Growth (TGG). This approach aims to develop lead-free piezoelectric materials with grain alignment during printing process to promote high piezoelectric performance comparable to those in lead-based ceramics. This research evaluates the impact of the DIW-TGG process on grain orientation, material densification, and piezoelectric response, illustrating its potential for developing high-performance ceramics for advanced applications such as sensors, actuators, and other piezoelectric devices. The second project explores the chemical stability …

Redefining Approaches For Measuring Landscape Subsidence And Permafrost Degradation In Arctic Tundra Environments, Tabatha Lynn Fuson

Open Access Theses & Dissertations

As climate change accelerates in the Arctic, the degradation of permafrost is leading to significant landscape transformation in tundra landscapes. This dissertation investigates the multifaceted responses of permafrost systems to warming, focusing on the dynamics of surface elevation changes and active layer thickness (ALT) across the North Slope of Alaska. In this study, I explore the capacity of repeat Terrestrial Laser Scanning (TLS) technology for modeling tundra features and detecting surface subsidence, specifically how different climate and landscape conditions during scanning impact TLS model precision. We also compare TLS model precision estimates to TLS model accuracy by comparing elevation values …

General Purpose Gpu Benchmarks For Neural Networks, Jose Maria Granados

Open Access Theses & Dissertations

Neural networks are a field of computing experiencing a rise in popularity in recent years due to the utilization of graphics processing units as their computational centerpiece. The lack of neural network benchmarks for the open-source Nyuzi architecture, a developing general-purpose processor with graphical processing capabilities, is the focus of this thesis. This work aims to determine whether Nyuziâ??s performance counters and traceable events suffice for performance tuning of neural network implementations. Given the mathematical intensity of neural networks, a strong emphasis is placed on events related to arithmetic instructions. Experimenting with neural network implementations in C and C++, existent …

Vertically Aligned Nickel Cobalt Molybdenum Copper Oxide Nanotubes For High Performance Asymmetric Supercapacitors, Ricardo Herrera Aguirre

Open Access Theses & Dissertations

Designing materials having novel multi metal oxide electrodes with controlled structure and composition is a critical technological challenge for high performance supercapacitor applications. Quaternary metal oxides have attracted considerable attention in this field, where many methods have been used to improve their performance. In the present work, the nickel cobalt molybdenum copper oxide (NCMCuO2) has been synthesized using a hydrothermal method. The effect of different concentrations of Cu doping (0.5%,1.0% and 2.0%) on the NCM frame and structural and electrochemical properties of the quaternary metal oxide (NCMCuO2) are studied thoroughly. The XRD pattern of synthesized NCMCuO2 exhibited predominant (002) orientation …

Critical Analysis Of Archival Data: The Alvarado V. Episd Case, Mauro Alfredo Hinojosa

Open Access Theses & Dissertations

This research analyses the Alvarado vs. El Paso Independent School District legal files, housed at the Sonnichsen Special Collections Department, The University of Texas at El Paso Library. This dissertation explored the following questions: Research question 1 (RQ1): What are the political and social-cultural contexts of the Alvarado case based on the Archives?; and Research Question 2 (RQ2): impact on school education, to include themes in policy and leadership. A qualitative research approach framed through Latino Critical Race Theory exposes how the U.S. education system has historically reinforced White perspectives and marginalized Latino groups, specifically focusing on Mexican-American students in …

Chipless 3d Microfluidic Rf Sensing, Sheikh Dobir Hossain

Open Access Theses & Dissertations

Effective management of the cold chain is essential to uphold the quality and safety of products vulnerability to physical factors like temperature, humidity, pressure, etc., including perishable foods, pharmaceuticals, and vaccines. Chipless Radio Frequency Identification (RFID) sensors have become increasingly favored as a viable technology for tracking, inventory, and sensing industries due to their wireless and non-line of sight (NLOS) situations, straightforward fabrication, cost efficiency, and adaptability to challenging environmental conditions. However, there is still a need for advancements in RFID sensors to make them promise for cold chain applications. Integration of flexibility and non-volatile memory into the existing RFID …

Thermal Analysis Of Combustion Synthesis Of Fealxoy Catalysts For Dehydrogenation Of Fossil Fuels, Laura Alejandra Martinez Espinoza

Open Access Theses & Dissertations

The growing demand for hydrogen as a clean energy carrier highlights the need for its alternative production method with reduced CO₂ emissions. Microwave-assisted thermocatalytic dehydrogenation of fossil fuels offers a promising solution for clean hydrogen production, with FeAlxOy nanocomposites acting as efficient catalysts due to their thermal stability, catalytic activity, and microwave-absorption properties. FeAlxOy nanocomposites, fabricated by solution combustion synthesis (SCS), have shown good microwave-absorption and catalytic properties. However, the effects of synthesis parameters such as fuel type and Fe:Al molar ratio on the SCS process and properties of the final material are not well understood. The SCS process involves …

Elucidating The Effect Of Milled Glass And Graphite Fiber On The Quasi-Static Properties Of Vinyl Ester Resin Composites, Sarahi Mendivil

Open Access Theses & Dissertations

Composite materials can be tailored to various applications, making them one of the most conventional materials. Their ability to enhance desired characteristics enables higher strength while maintaining light weight. However, understanding defects and manufacturing limitations is crucial for optimizing their fabrication processes. This paper focuses on the manufacturing processes of open molding with controlled variations to establish an optimal technique aimed at minimizing defects, such as bubble formation where the focus is on mitigating defects and ensuring uniform dispersion of fiber in fiber-reinforced composites. After refining the manufacturing process, composites with varying resin-to-fiber concentration ratios were manufactured using glass and …

Ultra-High Temperature Ceramics: Materials, Manufacturing, And Machine Development, Joseph Matthew Munoz

Open Access Theses & Dissertations

This research aimed to advance the 3D printing of ultra-high-temperature ceramic matrix composites (UHTCMCs) and develop a custom Direct Ink Writing (DIW) system with multimaterial and in-line mixing capabilities. The study first focused on creating ZrB₂–SiC composites reinforced with aligned silicon carbide fibers (SiCf) using paste extrusion. By formulating suspensions with a preceramic polymer (SMP-10), ZrB₂, and SiCf, the study assessed how fiber alignment influenced key properties such as thermal and electrical conductivity and mechanical strength. Green curing and pyrolysis transformed the printed parts into UHTCMCs, with results showing substantial improvements in thermal conductivity—nearly double that of non-aligned parts—and a …

A Blue Hydrogen Framework For Regional Energy Resiliency, Safwan Shafquat

Open Access Theses & Dissertations

High-pressure gasification is gaining attention as an emerging solution for sustainable energy production due to its potential to achieve higher efficiencies, improved syngas quality and smaller equipment footprints. High operating pressures and temperatures can increase the synergistic reactivity of biomass and organic materials, consequently enabling higher in situ tar reformation and ultimately reducing the number of gas treatment requirements. Additionally, higher operating pressures result in a more concentrated CO2 stream and reduce the amount of post-gasification compression requirements in the carbon capture and storage (CCS) unit, improving overall system efficiency. Plus, pressurized CO2 streams from the gasifier also provides routes …

Assessing Sedimentation Impact Through Dem, Point Cloud, And Discharge Analysis, Shandell Thomas

Open Access Theses & Dissertations

This study focused on five arroyos flowing into the Rio Grande, in the stretch between Caballo Dam and Las Cruces, New Mexico. Drone imagery was acquired from study areas in each arroyo. Photogrammetry was used to create high-resolution digital elevation models (DEMs), point clouds, drone imagery and potential discharges were acquired for each arroyo. Investigation of seven different methods resulted in the selection of the Terrain Ruggedness Map (TRM) as a predictor of surface roughness, along with high-resolution DEMâ??s to illustrate small and low-relief channel features. The five arroyos with varying sediment sizes and characteristics were studied to understand how …

Rockets, Rovers, And Rocks, Oh My!, Tara Lynn Sweeney

Open Access Theses & Dissertations

This body of work undertakes three distinct projects, all with the ultimate goal of improving the future efforts of human space exploration.Chapter 2 is a seismic analysis of rocket launch and landing operations. Being able to identify and understand anthropogenically induced seismic signals in comparison to naturally occurring seismic signals is an important step in characterizing and monitoring both types of signals on the Moon. Relatively few terrestrial studies have been performed to explore this, but there is a growing opportunity to record, discern, and understand the differences between anthropogenic and naturally occurring seismic signals due to the increasing pace …

East Texas Master Gardener Characteristics, Volunteer Choices, And Willingness To Answer Questions From The Public, Damon Gregory Grant

Electronic Theses and Dissertations

East Texas Master Gardener volunteers were asked to participate in an exploratory Qualtrics survey during the fall of 2023. This study examined the demographic characteristics, volunteer engagement choices, and challenges of Master Gardener volunteers in Texas A&M AgriLife Extension Service District 5, focusing on whether current training adequately prepares volunteers for public-facing roles. Findings showed that volunteers were primarily older, retired, well-educated, white females, favoring hands-on activities like garden demonstrations and fundraising over Help Desk question answering roles due to perceived inadequacies in knowledge. Over 80% indicated that mentorship and advanced training could improve their confidence in public interactions. Recommendations …

Gate Driver Design In High-Temperature Cmos Process For Heterogeneous Integration Inside Sic Power Module, Khandoker Asif Faruque

Graduate Theses and Dissertations

The shift toward electrification in transportation, including electric and hybrid vehicles, presents challenges for power electronic converters. Silicon Carbide (SiC) power devices are promising due to their high efficiency, temperature tolerance, and reduced losses compared to traditional silicon devices. However, their use is hindered by issues such as parasitic capacitances and gate inductances, which can lead to voltage spikes and stress on the device gate oxide, hence impacting converter reliability. Increasing gate resistance can help manage these issues, but it reduces switching speed and increases losses. Snubber circuits can mitigate switching stress but add extra components, reducing efficiency. Active gate …

Towards Robust And Fair Vision Learning In Open-World Environments, Thanh-Dat Truong

Graduate Theses and Dissertations

The rapid increase of large-scale data and high-performance computational hardware has promoted the development of data-driven machine vision approaches. Advanced deep learning approaches have achieved remarkable performance in various vision problems and are closing the capability gap between artificial intelligence (AI) and humans. However, towards the ultimate goal of AI, which replicates human ability in visual perception tasks, the machine vision learning methods still need to address several ill-posed challenges. First, while the current vision learning methods often rely on large-scale annotated data, the data annotation process is a costly and time-consuming process. Second, the unfaired predictions produced by vision …

Neural Network Architecture Search Enabled Wide-Deep Learning (Nas-Wd) Integrated Hyperspectral Imaging Understanding For Woody Breast In Poultry Processing, Chaitanya Kumar Reddy Pallerla

Graduate Theses and Dissertations

The development and implementation of a Wide & Deep (WD) learning model tailored for classification and regression tasks utilizing spectral data provides a robust solution to evaluate woody breast (WB) conditions in poultry fillets. This process begins with thorough data preprocessing, which includes loading spectral and classification datasets, imputing missing values with medians, and splitting the data into training and testing sets to ensure rigorous model evaluation. The WD model architecture integrates wide linear models and deep neural networks to harness the strengths of both approaches. The wide component excels at memorizing sparse feature interactions, while the deep component captures …

Roger Williams University 2024 President's Report: A Message From President Miaoulis, Roger Williams University

Life of the Law School (1993- )

No abstract provided.

Relationship Between Host Genomics And Microbiomics In Beef Cattle, Andrew D. Lakamp

Department of Animal Science: Dissertations, Theses, and Student Research

As sequencing technology becomes more affordable and throughput increases, microbiome information is becoming more readily available. For beef cattle selection, microbial information has a variety of uses including being a target for genetic prediction or used as a means to explicitly describe additional phenotypic variability in other traits.

Infectious bovine keratoconjunctivitis (IBK), commonly known as pinkeye, is a disease that infects the ocular surface and surrounding tissue which is an animal health and producer economic concern. Vaccinations have shown to have variable effectiveness, while limited genetics studies have suggested that direct genetic selection for resistance would be slow. Therefore, an …

Grant Writing: The Essentials, Jayme Renfro

Faculty Book Gallery

Welcome to the exciting and impactful world of grant writing! Whether you are a student embarking on a career in nonprofit management, a budding researcher eager to secure funding for your projects, or a professional looking to hone your grant writing skills, this textbook is designed to guide you through every step of the grant writing process. Grant writing is not just about securing funds; it's about crafting a story, building relationships, and making a tangible impact on communities and fields of study. This book aims to equip you with the knowledge, skills, and insights needed to excel in this …

Virtual Control: A Comparison Of Methods For Hand-Tracking Implementation, Nathan Roberts

Honors Program: Senior Projects (Public)

This thesis examines the design philosophy of modern virtual reality applications that utilize hand-tracking as a primary form of user input. The analysis presented hopes to provide ideas for future implementations of this technology so that more immersive experiences are developed. This analysis starts with the discussion of a modern example of successful hand-tracking implementation, then comparing that implementation to a recent senior design project. This comparison is primarily based on each experience’s ability to create interactivity and immediacy. Interactivity is the degree to which the user can quickly and reliably make changes to their virtual environment, while immediacy is …

Nebraska Department Of Transportation Strategic Audit, Chloe Hoover

Honors Program: Senior Projects (Public)

The Nebraska Department of Transportation (NDOT) is a state government agency that is responsible for the planning, development, design, construction, maintenance, and administration of the state highway system. Two strategic analyses are completed about NDOT: a PESTEL analysis and Porter’s Five Forces analysis. Both of these analyses showed that since NDOT is a state agency, it impacts foundational aspects of its strategy. NDOT’s strategy is influenced by its financial strategy, policies or political influence, and public importance. NDOT competes with other companies in its workforce and employees and/or applicants leaving NDOT for other companies. This report details NDOT’s strategy, competitive …

An Overview Of Planning For Vehicle-To-Grid Systems With Large-Scale Adoption Of Electric Vehicles, Fazel Mohammadi, Mahmood Mirhashemi

Electrical & Computer Engineering and Computer Science Faculty Publications

The rapid adoption of Electric Vehicles (EVs) has the potential to transform energy infrastructure worldwide. Vehicle-to-Grid (V2G) systems, which enable bidirectional energy flow between EVs and power grids, offer a promising solution for balancing electricity demand, supporting renewable energy integration, and enhancing the resilience of power grids. This paper explores different strategic planning considerations necessary for the large-scale adoption of V2G-enabled EVs, aiming to support a more resilient and sustainable energy infrastructure.

Talimogene Laherparepvec (T-Vec) And Emerging Intralesional Immunotherapies For Metastatic Melanoma: A Review, Peter Mcgranaghan

All Publications

Purpose of review: As the incidence of cutaneous melanoma continues to rise worldwide, its heterogeneous presentation proves challenging for managing and preventing relapse.

Recent findings: While surgery remains a mainstay in staging and treatment of locoregional metastatic melanoma, intralesional therapies have emerged as a new tool to treat unresectable in-transit and nodal metastases and reduce the risk of relapse through immunomodulatory mechanisms. In this review, we will provide an overview of intralesional therapies for melanoma with a particular focus on talimogene laherparepvec (T-VEC) and its future uses. We then discuss the landscape of current and emerging intralesional therapies.

Fitting Quality Of Nmr Relaxation Data To Differentiate Asphalt Binders, Rebecca M. Herndon, Kevin Lai, Magdy Abdelrahman, Klaus Woelk

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Asphalt binder performance grades (PGs) are important metrics in designing pavements for effective transportation infrastructure. the PG system relies on the binder's stiffness and is determined through energy- and time-intensive physical testing. Physical properties, like stiffness, can also be determined by spin–lattice NMR relaxometry, a non-destructive chemical method. NMR relaxometry can quantify the molecular mobility of materials by determining relaxation times from exponential decays of excited nuclear magnetization. While relaxation times have been used to determine physical properties of materials, a quantitative relation to the PG grades of asphalt binder is yet to be established. in this study, T1 NMR …

Issue 41

The Synapse: Intercollegiate science magazine

No abstract provided.