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Understanding Global Street Food Consumer Behavior And Experience: A Narrative Review Of Literature And Development Of Framework, Samit Chakravorti Dec 2024

Understanding Global Street Food Consumer Behavior And Experience: A Narrative Review Of Literature And Development Of Framework, Samit Chakravorti

Journal of Applied Marketing Theory

This paper explores global street food consumer behavior and consumption experience. The aim of this paper is to gain a holistic comprehension of street food consumption decision making and experience through exploring nature and sources of perceptions, attitude and expectations surrounding street food, the characteristics of the product offering and the domain within which it is served and consumed. To achieve this aim the author engages in a narrative review of academic research on consumer behavior of street food, provides a holistic picture of consumption experience of street food through consolidating and interpreting research findings, and extends the theoretical understanding …


Measuring Social Influence In Online Social Networks - Focused Literature Review On Human Behaviors, Shyamala N. Chalakudi, Gnana Bharathy, Dildar Hussain, Dakshinamurthy Kolluru Dec 2024

Measuring Social Influence In Online Social Networks - Focused Literature Review On Human Behaviors, Shyamala N. Chalakudi, Gnana Bharathy, Dildar Hussain, Dakshinamurthy Kolluru

Journal of Applied Marketing Theory

Measuring an individual's social influence (SI) capability is gaining traction with the rapid growth and expansive reach of online social networks (OSN). However, most existing frameworks and methods are confined to graphical theories or the structural properties of these networks. Even behavioral investigations are often limited to a narrow set of influencing behaviors and confront significant challenges in encompassing the breadth of human psychological characteristics. This study aims to address this gap through an exhaustive and focused literature review, concentrating on the definitions of human behavior characteristics rooted in established sociology and psychology theories. Beyond providing a comprehensive overview, the …


Neutrosophic Cox Proportional Hazards Model For Robust Variable Selection In Survival Analysis, Ibrahim Yasser, Aya A. Abd El-Khalek, A. A. Salama, Doaa A. Abdo Dec 2024

Neutrosophic Cox Proportional Hazards Model For Robust Variable Selection In Survival Analysis, Ibrahim Yasser, Aya A. Abd El-Khalek, A. A. Salama, Doaa A. Abdo

Neutrosophic Systems with Applications

This paper introduces a novel approach for variable selection in survival analysis by integrating neutrosophic logic into the Cox Proportional Hazards (Cox PH) model to address the limitations of recent studies related to high dimensionality. Neutrosophic logic, is a mathematical framework that allows for uncertainty, indeterminacy, and inconsistency, and particularly well suited for handling the complexity and often-ambiguous nature of biological data. By incorporating neutrosophic sets into the Cox PH model, we aim to enhance model robustness, improve variable selection, and address the curse of dimensionality. We compare the performance of the neutrosophic-enhanced Cox PH model with traditional variable selection …


Multi-Criteria Decision-Making Approach Based On Correlation Coefficient For Multi-Polar Interval-Valued Neutrosophic Soft Set, Hamza Naveed, Saalam Ali Dec 2024

Multi-Criteria Decision-Making Approach Based On Correlation Coefficient For Multi-Polar Interval-Valued Neutrosophic Soft Set, Hamza Naveed, Saalam Ali

Neutrosophic Systems with Applications

The correlation coefficient between two factors is crucial in statistical computation, indicating the extent and evolution of the appropriate link. The precision of applicability evaluations frequently relies on the thoroughness and caliber of data obtained from a certain dataset. Statistical research sometimes entails data marked by intrinsic trade-offs and uncertainty. This study seeks to present m-polar interval-valued neutrosophic soft sets (mPIVNSSs) through the integration of m-polar fuzzy sets with interval-valued neutrosophic soft sets. The suggested mPIVNSS structure is a significantly generalized version of m-polar neutrosophic soft sets and serves as a substantial extension of interval-valued neutrosophic soft sets. In this …


Analysis Of Bck/Bci-Algebras Based On Bipolar Complex Intuitionistic Fuzzy Soft Ideals, Zeeshan Ali Dec 2024

Analysis Of Bck/Bci-Algebras Based On Bipolar Complex Intuitionistic Fuzzy Soft Ideals, Zeeshan Ali

Neutrosophic Systems with Applications

In this article, we design an informative and reliable technique of bipolar complex intuitionistic fuzzy soft sets with numerous operational laws by merging the model of soft sets, complex fuzzy sets, and bipolar intuitionistic fuzzy sets to handle imprecise data. In addition, an ideal in a BCK-algebra is derived based on bipolar complex intuitionistic fuzzy soft set theory are proposed which can capture the information of hesitancy, vagueness, and non-membership information within the circumstance of BCK-algebra. Moreover, we design union, intersection, AND, and OR based on bipolar complex intuitionistic fuzzy soft ideal and simplify it with the help of numerous …


Comparative Analysis Of Multi-Criteria Techniques In Neutrosophic Environment And Their Applications To Economic Condition Assessment, Asmaa Elsayed, Mai Mohamed Dec 2024

Comparative Analysis Of Multi-Criteria Techniques In Neutrosophic Environment And Their Applications To Economic Condition Assessment, Asmaa Elsayed, Mai Mohamed

Neutrosophic Systems with Applications

In economic decision-making, the challenge of evaluating multiple, often conflicting criteria necessitates advanced Multi-Criteria Decision-Making (MCDM) techniques. Traditional methods can struggle with the inherent uncertainty, ambiguity, and imprecision of real-world data. This paper addresses these challenges by investigating the effectiveness of various MCDM techniques within neutrosophic environments, with a particular focus on the Criteria-wise Alternatives Ranking and Correlation Analysis for Composite Scoring (CARCACS) method. Neutrosophic sets, which incorporate truth, falsity, and indeterminacy, provide a robust framework for addressing the vagueness and inconsistencies found in economic indicators such as GDP growth, employment levels, inflation rates, trade balances, investment activity, and government …


End-To-End Learning For A Low-Cost Robotics Arm, Abhishek Chothani Dec 2024

End-To-End Learning For A Low-Cost Robotics Arm, Abhishek Chothani

Theses and Dissertations

Robotic manipulation is a cornerstone of automation, with the ultimate goal of developing versatile systems capable of executing a wide range of real-world tasks autonomously. Traditional robotics approaches, while reliable and widely adopted in industrial settings, often struggle with adaptability, perception, and dynamic task execution. This thesis explores the evolution from classical robotics techniques to modern learning-based approaches, leveraging advancements in artificial intelligence to overcome these limitations.

Initially, the thesis presents a pick-and-place pipeline built using the Drake robotics framework and the KUKA iiwa robotic arm. This system employs a pseudoinverse controller for inverse kinematics to perform structured tasks like …


Fabrication And Performance Of Scalable Bio-Engineered Porous Layers For Efficient Co2 Capture, Mary Sharon Rose Bondugula Dec 2024

Fabrication And Performance Of Scalable Bio-Engineered Porous Layers For Efficient Co2 Capture, Mary Sharon Rose Bondugula

Theses and Dissertations

This dissertation addresses the critical challenge of mitigating climate change by advancing CO2 capture technologies. As global CO2 emissions continue to rise, effective methods for capturing and separating CO2 from industrial processes are essential to combat climate change. Existing CO2 capture systems, such as Pressure Swing Adsorption (PSA) and Temperature Swing Adsorption (TSA), often rely on packed bed designs that face limitations, including poor heat and mass transfer, slow gas diffusion, and low thermal conductivity, reducing their efficiency. To overcome these challenges, this dissertation explores innovative solutions by developing advanced adsorbent coatings and scalable bed configurations.

This research begins by …


Patterns Of Interactions In Human-Machine Teams, Kazuhiko Momose Dec 2024

Patterns Of Interactions In Human-Machine Teams, Kazuhiko Momose

Theses and Dissertations

Increasingly capable machines, including Artificial Intelligence (AI) agents are playing a more important role in a wide range of applications, including human daily activities and safety-critical systems. They can benefit even more when humans and such machines agents work together as a team by leveraging each other's strengths and complementing each other to enhance overall performance. To design high-performing teams, it is critical to analyze the team dynamics and understand how humans and machines interact with each other. Collaboration, Coordination, and Cooperation (3Cs) are terms typically used to describe the behavior of teams. However, these terms tend to be used …


Loss Of Control In General Aviation: An Investigation Into The Mooney M20 And The Full Trimming Tail Design, Trenton Neil Wright Dec 2024

Loss Of Control In General Aviation: An Investigation Into The Mooney M20 And The Full Trimming Tail Design, Trenton Neil Wright

Theses and Dissertations

Loss of Control (LOC) in General Aviation (GA) remains one of the leading causes of aviation accidents, with 94% of all accidents in 2022 occurring in this sector, and 42% attributed directly to LOC [2][3]. This thesis focuses on the Full Trimming Tail (FTT) in Mooney aircraft, hypothesizing that the FTT design significantly increases the likelihood of LOC, particularly during go-arounds and touch-and-go landings. Prior studies have shown that certain trim systems can amplify pitch-up moments following rapid configuration changes, leading to stalls or LOC if not adequately managed by the pilot [23][24][25].

This research utilized a combination of logistic …


The Design And Implementation Of A Modular Tissue Engineering Test Bed To Pursue An Alternate Pathway Of Cell Culture Based Research, Ryley Patrick Griffin Dec 2024

The Design And Implementation Of A Modular Tissue Engineering Test Bed To Pursue An Alternate Pathway Of Cell Culture Based Research, Ryley Patrick Griffin

Theses and Dissertations

The development of a Modular Automated Tissue Engineering Test Bed (MATETB) is the next step in the development of cheap and easily available in vitro cell regulatory systems for both academic and industrial purposes. This project outlined the framework and requirements for a device that could automatically regulate and collect data on a cell culture through the manipulation of its liquid environment. From this framework, a prototype was built. The device would fulfill cell culture needs while collecting data automatically and allowing for live viewing and imaging of cells. The device was comprised of a mechanical skeleton (MS), an environmental …


Fabrication And Charcaterization Of Pullulan-Collagen Nanofibers Via Forcespinning, Valeria Leon Leal Dec 2024

Fabrication And Charcaterization Of Pullulan-Collagen Nanofibers Via Forcespinning, Valeria Leon Leal

Theses and Dissertations

Extensive research on collagen has spurred advancements in tissue engineering and biomaterial development, given collagen´s pivotal role in regulating various tissue structures across diverse organisms. This study delves into fabricating nanocomposites utilizing collagen, along with silver nanoparticles, chondroitin sulfate and pullulan, for potential applications in antibacterial medical devices, and cell regeneration. Collagen, abundant in the extracellular matrix, provides essential structural support, while silver nanoparticles and chondroitin confer antimicrobial properties, crucial for combating infections. Pullulan, a polysaccharide polymer, serves as a biocompatible carrier for silver nanoparticles whilst being the starting nanofiber forming material. Utilizing Forcespinning® technology, composite nanofibers were successfully synthesized. …


Aid Or Abuse? A Review Of U.S. Police Assistance Programs In Latin America During The Early Cold War, Brianna Mcnally Dec 2024

Aid Or Abuse? A Review Of U.S. Police Assistance Programs In Latin America During The Early Cold War, Brianna Mcnally

War, Diplomacy, and Society (MA) Theses

During the Cold War, the United States used police assistance programs in under-developed countries to stop the spread of communism. Police aid aimed to improve a country’s economic stability and internal security to curb the rise of communist revolutions. The U.S. government charged the Office of Public Safety (OPS) within the U.S. Agency for International Development (USAID) with managing police assistance programs around the world, including in Asia, Africa, and Latin America.

Despite its seemingly good intentions, the OPS became a short-lived program now known today for its ties to human rights abuses, especially throughout Latin America. Several Latin American …


Factors Influencing Colostrum Avoidance In Developing Countries: Insights From A Literature Review, Muhammad Zeeshan Aslam, Jonathan Johnson, Marina Baig, Abeer Musaddique Dec 2024

Factors Influencing Colostrum Avoidance In Developing Countries: Insights From A Literature Review, Muhammad Zeeshan Aslam, Jonathan Johnson, Marina Baig, Abeer Musaddique

Journal of Asian Midwives (JAM)

Introduction: Colostrum is a thick, sticky, clear and yellowish-coloured milk produced after the first few hours of birth until day 3. It consists of vitamin A, proteins, lipids, potassium, and maternal antibodies, including lactoferrin, immunoglobulin, growth factors and antimicrobial factors. Colostrum avoidance is the practice of squeezing out, pumping, and discarding the first milk. Various studies have reported colostrum avoidance worldwide, but its prevalence is higher in developing countries. Every day, approximately 3000 to 4000 infants die due to diarrhea and respiratory infections in developing countries, and one of the leading causes is colostrum avoidance. Infants are unable to take …


A Techno-Economic Perspective On Efficient Hybrid Renewable Energy Solutions In Douala, Cameroon’S Grid-Connected Systems, Reagan Jean Jacques Molu, Serge Raoul Dzonde Naoussi, Mohit Bajaj, Patrice Wira, Wulfran Fendzi Mbasso, Barun K. Das, Milkias Berhanu Tuka, Arvind R. Singh Dec 2024

A Techno-Economic Perspective On Efficient Hybrid Renewable Energy Solutions In Douala, Cameroon’S Grid-Connected Systems, Reagan Jean Jacques Molu, Serge Raoul Dzonde Naoussi, Mohit Bajaj, Patrice Wira, Wulfran Fendzi Mbasso, Barun K. Das, Milkias Berhanu Tuka, Arvind R. Singh

Research outputs 2022 to 2026

Cameroon is currently grappling with a significant energy crisis, which is adversely affecting its economy due to cost, reliability, and availability constraints within the power infrastructure. While electrochemical storage presents a potential remedy, its implementation faces hurdles like high costs and technical limitations. Conversely, generator-based systems, although a viable alternative, bring their own set of issues such as noise pollution and demanding maintenance requirements. This paper meticulously assesses a novel hybrid energy system specifically engineered to meet the diverse energy needs of Douala, Cameroon. By employing advanced simulation techniques, especially the Hybrid Optimization Model for Electric Renewable (HOMER) Pro program, …


Responding To The Workforce Crisis: Consensus Recommendations From The Second Workforce Summit Of The American Society Of Pediatric Nephrology., Danielle E. Soranno, Sandra Amaral, Isa Ashoor, Meredith A. Atkinson, Gina-Marie Barletta, Michael C. Braun, Joann Carlson, Caitlin Carter, Annabelle Chua, Vikas R. Dharnidharka, Keri Drake, Elif Erkan, Dan Feig, Stuart L. Goldstein, David Hains, Lyndsay A. Harshman, Elizabeth Ingulli, Alexander J. Kula, Mary Leonard, Sudha Mannemuddhu, Shina Menon, Zubin J. Modi, Marva Moxey-Mims, Arwa Nada, Victoria Norwood, Michelle C. Starr, Priya S. Verghese, Darcy K. Weidemann, Adam Weinstein, Jodi Smith Dec 2024

Responding To The Workforce Crisis: Consensus Recommendations From The Second Workforce Summit Of The American Society Of Pediatric Nephrology., Danielle E. Soranno, Sandra Amaral, Isa Ashoor, Meredith A. Atkinson, Gina-Marie Barletta, Michael C. Braun, Joann Carlson, Caitlin Carter, Annabelle Chua, Vikas R. Dharnidharka, Keri Drake, Elif Erkan, Dan Feig, Stuart L. Goldstein, David Hains, Lyndsay A. Harshman, Elizabeth Ingulli, Alexander J. Kula, Mary Leonard, Sudha Mannemuddhu, Shina Menon, Zubin J. Modi, Marva Moxey-Mims, Arwa Nada, Victoria Norwood, Michelle C. Starr, Priya S. Verghese, Darcy K. Weidemann, Adam Weinstein, Jodi Smith

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Pediatric patients with complex medical problems benefit from pediatric sub-specialty care; however, a significant proportion of children live greater than 80 mi. away from pediatric sub-specialty care.

OBJECTIVE: To identify current knowledge gaps and outline concrete next steps to make progress on issues that have persistently challenged the pediatric nephrology workforce.

EVIDENCE REVIEW: Workforce Summit 2.0 employed the round table format and methodology for consensus building using adapted Delphi principles. Content domains were identified via input from the ASPN Workforce Committee, the ASPN's 2023 Strategic Plan survey, the ASPN's Pediatric Nephrology Division Directors survey, and ongoing feedback from ASPN …


2021 Carroll County Advisory Council Minutes And Agendas, Mikayla Cerney Dec 2024

2021 Carroll County Advisory Council Minutes And Agendas, Mikayla Cerney

UNH Cooperative Extension

No abstract provided.


Swinging On Windmills Of Love, Life, And Law: The Quixotic Pursuits Of Upendra Baxi (Book Review Of 'Of Law And Life: Upendra Baxi In Conversation With Arvind Narrain, Lawrence Liang, Sitharamam Kakarala, And Sruti Chaganti'), Amita Dhanda Dec 2024

Swinging On Windmills Of Love, Life, And Law: The Quixotic Pursuits Of Upendra Baxi (Book Review Of 'Of Law And Life: Upendra Baxi In Conversation With Arvind Narrain, Lawrence Liang, Sitharamam Kakarala, And Sruti Chaganti'), Amita Dhanda

National Law School Journal

This book review begins by elaborating on the melange of forms adopted by Of Law and Life: Upendra Baxi in Conversation with Arvind Narrain, Lawrence Liang, Sitharamam Kakarala, and Sruti Chaganti (Orient BlackSwan 2024). It then reflects on the different themes emerging from this narrative on Baxi’s life and work. The review next dwells on the book’s pedagogic possibilities. Since the book is not a comprehensive but a selective narrative of Baxi’s ‘law and life’, there are matters that have not been included in it—the author concludes the review by giving voice to these silences.


Stress-Dependent Instantaneous Cohesion And Friction Angle For The Mohr–Coulomb Criterion, Hao Li, Leo Pel, Zhenjiang You, David Smeulders Dec 2024

Stress-Dependent Instantaneous Cohesion And Friction Angle For The Mohr–Coulomb Criterion, Hao Li, Leo Pel, Zhenjiang You, David Smeulders

Research outputs 2022 to 2026

The strength criterion of rock is essential for stability control and safety design of geotechnical engineering constructions. Due to its widespread adoption, the Mohr–Coulomb (M-C) criterion is prominent among strength criteria. However, the M-C criterion is constrained by three significant limitations: it fails to capture the nonlinear strength response, overlooks the critical state, and disregards σ2. This study introduces a novel Stress-dependent Instantaneous Friction angle and Cohesion (SIFC) model for the M-C criterion to represent the convex strength envelope of intact rock, covering the spectrum from non-critical to critical states. In pursuit of this objective, an innovative approach for calculating …


Portable Multiplexed Ion-Selective Sensor For Long-Term And Continuous Irrigation Water Quality Monitoring, Mojtaba Abdollahzadeh, Yujie Zhu, Bita Bayatsarmadi, Mikko Vepsäläinen, Amir Razmjou, Krishnan Murugappan, Theo Rodopoulos, Mohsen Asadnia Dec 2024

Portable Multiplexed Ion-Selective Sensor For Long-Term And Continuous Irrigation Water Quality Monitoring, Mojtaba Abdollahzadeh, Yujie Zhu, Bita Bayatsarmadi, Mikko Vepsäläinen, Amir Razmjou, Krishnan Murugappan, Theo Rodopoulos, Mohsen Asadnia

Research outputs 2022 to 2026

In agricultural contexts, the demand for continuous and precise measurement of multiple ions is crucial. While arrays of solid-contact ion-selective electrodes (SCEs) have been developed previously, there has been limited emphasis on their continuous and long-term monitoring of ions. Addressing this gap, our work introduces an innovative sensor array utilizing Ni-HAB MOF as an ion-to-electron transducer, enabling real-time detection of nitrate, potassium, and pH levels. The sensors exhibit exceptional stability, eliminating the need for frequent recalibration. For instance, the K+-selective sensor displays an unprecedentedly low potential drift of 0.05 µV/h, surpassing existing solid-contact sensors by two orders of magnitude. Similarly, …


Corrosion Behavior Of Laser Powder Bed Fusion Additive Manufacturing Produced Tini Alloy By Micro-Arc Oxidation, Xin Zhao, Yicheng Liu, Chenfan Jia, Hao Chang, Wei Zhang, Yun Bai, Shujun Li, Lai-Chang Zhang, Wei Yuan Dec 2024

Corrosion Behavior Of Laser Powder Bed Fusion Additive Manufacturing Produced Tini Alloy By Micro-Arc Oxidation, Xin Zhao, Yicheng Liu, Chenfan Jia, Hao Chang, Wei Zhang, Yun Bai, Shujun Li, Lai-Chang Zhang, Wei Yuan

Research outputs 2022 to 2026

To improve the corrosion resistance of TiNi alloy fabricated by laser powder bed fusion (LPBF), a porous oxidation layer was synthesized by micro-arc oxidation in a sodium aluminate and sodium silicate electrolyte. The influences of the applied voltage and the processing time on the morphology of oxidation layer were investigated, and the corrosion behavior of the oxidation layer in artificial saliva was evaluated and compared with that of the as-fabricated LPBF alloy. The results indicate that, as increasing the applied voltage and the processing time, the oxidation layer becomes uniform and integrated. The optimum parameters are with an applied voltage …


A Secure Cross-Domain Authentication Scheme Based On Threshold Signature For Mec, Lei Chen, Chong Guo, Bei Gong, Muhammad Waqas, Lihua Deng, Haowen Qin Dec 2024

A Secure Cross-Domain Authentication Scheme Based On Threshold Signature For Mec, Lei Chen, Chong Guo, Bei Gong, Muhammad Waqas, Lihua Deng, Haowen Qin

Research outputs 2022 to 2026

The widespread adoption of fifth-generation mobile networks has spurred the rapid advancement of mobile edge computing (MEC). By decentralizing computing and storage resources to the network edge, MEC significantly enhances real-time data access services and enables efficient processing of large-scale dynamic data on resource-limited devices. However, MEC faces considerable security challenges, particularly in cross-domain service environments, where every device poses a potential security threat. To address this issue, this paper proposes a secure cross-domain authentication scheme based on a threshold signature tailored to MEC’s multi-subdomain nature. The proposed scheme employs a (t,n) threshold mechanism to bolster system resilience and security, …


Template-Assisted Covalent Modification Underlies Activity Of Covalent Molecular Glues, Moritz Hunkeler, Mingxing Teng, Kedar Puvar, Justine C Rutter, Ryan J Lumpkin, Brittany Sandoval, Cyrus Y Jin, Anna M Schmoker, Scott B Ficarro, Hakyung Cheong, Rebecca J Metivier, Michelle Y Wang, Shawn Xu, Woong Sub Byun, Brian J Groendyke, Inchul You, Logan H Sigua, Isidoro Tavares, Charles Zou, Jonathan M Tsai, Paul M C Park, Hojong Yoon, Felix C Majewski, Haniya T Sperling, Jarrod A Marto, Jun Qi, Radosław P Nowak, Katherine A Donovan, Mikołaj Słabicki, Nathanael S Gray, Eric S Fischer, Benjamin L Ebert Dec 2024

Template-Assisted Covalent Modification Underlies Activity Of Covalent Molecular Glues, Moritz Hunkeler, Mingxing Teng, Kedar Puvar, Justine C Rutter, Ryan J Lumpkin, Brittany Sandoval, Cyrus Y Jin, Anna M Schmoker, Scott B Ficarro, Hakyung Cheong, Rebecca J Metivier, Michelle Y Wang, Shawn Xu, Woong Sub Byun, Brian J Groendyke, Inchul You, Logan H Sigua, Isidoro Tavares, Charles Zou, Jonathan M Tsai, Paul M C Park, Hojong Yoon, Felix C Majewski, Haniya T Sperling, Jarrod A Marto, Jun Qi, Radosław P Nowak, Katherine A Donovan, Mikołaj Słabicki, Nathanael S Gray, Eric S Fischer, Benjamin L Ebert

Faculty, Staff and Students Publications

Molecular glues are proximity-inducing small molecules that have emerged as an attractive therapeutic approach. However, developing molecular glues remains challenging, requiring innovative mechanistic strategies to stabilize neoprotein interfaces and expedite discovery. Here we unveil a trans-labeling covalent molecular glue mechanism, termed ‘template-assisted covalent modification’. We identified a new series of BRD4 molecular glue degraders that recruit CUL4DCAF16 ligase to the second bromodomain of BRD4 (BRD4BD2). Through comprehensive biochemical, structural and mutagenesis analyses, we elucidated how pre-existing structural complementarity between DCAF16 and BRD4BD2 serves as a template to optimally orient the degrader for covalent modification of DCAF16Cys58. This process stabilizes …


Bst2 Facilitates Activation Of Hematopoietic Stem Cells Through Erk Signaling, Holly A Hill, Youngjae Jeong, Brian M Ho, Pawel Kus, Trisha K Wathan, Bailee N Kain, Shixia Huang, Dongsu Park, Katherine Y King Dec 2024

Bst2 Facilitates Activation Of Hematopoietic Stem Cells Through Erk Signaling, Holly A Hill, Youngjae Jeong, Brian M Ho, Pawel Kus, Trisha K Wathan, Bailee N Kain, Shixia Huang, Dongsu Park, Katherine Y King

Faculty, Staff and Students Publications

The proinflammatory cytokine interferon-gamma (IFNγ) is upregulated in a variety of infections and contributes to bone marrow failure through hematopoietic stem cell (HSC) activation and subsequent exhaustion. The cell surface protein, bone marrow stromal antigen 2 (BST2), is a key mediator of this process, as it is induced upon interferon stimulation and required for interferon-dependent HSC activation. To identify the mechanism by which BST2 promotes interferon-dependent HSC activation, we evaluated its role in niche localization, immune cell function, lipid raft formation, and intracellular signaling. Our studies indicated that knock out (KO) of BST2 in a murine model does not disrupt …


Low Toxicity Of Dissolved Silver From Silver-Coated Titanium Dental Implants To Human Primary Osteoblast Cells, Ranj Nadhim Salaie, Alexandros Besinis, Christopher Tredwin, Richard D Handy Dec 2024

Low Toxicity Of Dissolved Silver From Silver-Coated Titanium Dental Implants To Human Primary Osteoblast Cells, Ranj Nadhim Salaie, Alexandros Besinis, Christopher Tredwin, Richard D Handy

School of Engineering, Computing and Mathematics

The controlled release of silver as a biocide from Ag-coated medical implants is desirable. However, the biocompatibility of Ag leachates is poorly understood. This study investigated the toxicity of silver released from the silver plated titanium implants to human primary osteoblast cells; and the effect of cell culture medium on the silver speciation and bioavailability.

METHODS: Ti6Al4V discs were coated with Ag nanoparticles (NPs), silver plus hydroxyapatite (HA) nanoparticles (Ag+nHA), or Ag NPs plus microparticles (Ag+mHA). Primary human osteoblast cells were exposed to the leachates from the various discs for up to 7 days.

RESULTS: the total Ag concentrations released …


Google Trends And Syphilis Dec 2024

Google Trends And Syphilis

Faculty, Staff and Students Publications

Objective: This study aims to assess the correlation between Centers for Disease Control-reported syphilis incidence rates and case burden and public interest in syphilis as indicated by Google search trends.

Methods: This study utilized Google Trends data to analyze popular syphilis-related search terms from 2013 to 2023. The latest Centers for Disease Control-reported syphilis incidence rates for 2022 were compared to Google Trends data to identify patterns or correlations.

Results: Google Trends data showed a 37.65-percent increase in average annual searches for syphilis-related terms in the United States from 2013 to 2023. The largest increase in search volume was observed …


Exploring Fibroblast Interactions On Nanocrystalline Surfaces In Physiological Environments Through A Phenomenological Lens Dec 2024

Exploring Fibroblast Interactions On Nanocrystalline Surfaces In Physiological Environments Through A Phenomenological Lens

Faculty, Staff and Students Publications

The cytological behaviour and functional dynamics (adhesion, spreading, synthesis of proteins) of fibroblasts when interacting with biomedical surfaces are intricately influenced by the inherent nature of surface (nanocrystalline or microcrystalline), where the nanocrystalline (NC) surface is preferred in relation to the microcrystalline (MC) surface. This preference is a direct consequence of the distinct differences in physical and chemical characteristics between NC and MC surfaces, which include crystal boundary bio-physical attributes, electron work function, surface energy, and charge carrier density. The observed variances in cytological behaviour at the interfaces of NC and MC bio-surfaces can be attributed to these fundamental differences, …


Barriers To Faculty Adoption Of Assessment: A Case Study In Engineering, Melodie A. R. Williams Dec 2024

Barriers To Faculty Adoption Of Assessment: A Case Study In Engineering, Melodie A. R. Williams

Theses and Dissertations

This case study at an undergraduate teaching-focused engineering program in a small faith-based liberal arts university is designed to evaluate tools for assessing the engineering accreditor ABET’s Student Outcome Five – teamwork skills of engineering students. This evaluation would set the foundation for developing an assessment program that meets the needs of faculty, administrators, and accreditors. Activity theory is used as the theoretical framework for the study. A literature review lays the foundation for a novel conceptual framework asserting “faculty resistance” is actually “systemic friction.” The methodology is described, including data collection procedures, data analysis methods, and the approaches to …


Spectrometric Detection Of Microplastics In The Environment: A Novel Approach Using Hyperspectral Imaging System, Mansurat Abdulmalik Ali Dec 2024

Spectrometric Detection Of Microplastics In The Environment: A Novel Approach Using Hyperspectral Imaging System, Mansurat Abdulmalik Ali

Theses and Dissertations

Microplastics (MPs), defined as plastic particles ranging from 1 μm to 5 mm, have emerged as one of the significant environmental contaminants due to their widespread presence in terrestrial and aquatic ecosystems. MPs originate from primary sources, such as industrial pre-production pellets and microbeads in personal care products, or secondary sources, such as the breakdown of larger plastic particles. Their persistence in the environment is due to their resistance to degradation and capacity to transport toxic substances and pathogens. These characteristics raise concerns about their ecological impacts and potential entry into food chains, ultimately affecting human health. Despite extensive research …


Exploring Green Photochemical Reactions Of Bio-Based Heterocyclic Compounds: 4-Hydroxy-2(5h) Furanone And 2-Pyridone, Solmaz Asadi Dec 2024

Exploring Green Photochemical Reactions Of Bio-Based Heterocyclic Compounds: 4-Hydroxy-2(5h) Furanone And 2-Pyridone, Solmaz Asadi

Theses and Dissertations

The present work examines the photoreactivity of 4-hydroxy-2(5H)-furanone and 2-pyridone un-der varying conditions, with the aim of investigating how solvent and wavelength can influence their photochemical reactivity. In the first chapter, the photoreactivity of 4-hydroxy-2(5H)-furanone in its crystalline state was observed to undergo a [2+2] photocycloaddition reaction when exposed to UV-C light and led to a new cyclobutane containing dimer (CB-SA-1). More impressively, CB-SA-1 was determined to be stable at room temperature for two years. This method was solvent-free and catalyst-free offering an environmentally friendly method for synthesizing furanone deriva-tives. Further, in order to study the photoreactivity of 4-hydroxy-2(5H)-furanone in …