Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Engineering (198078)
- Physical Sciences and Mathematics (119504)
- Social and Behavioral Sciences (111667)
- Education (77402)
- Law (76646)
-
- Arts and Humanities (69657)
- Life Sciences (49566)
- Computer Sciences (46115)
- Medicine and Health Sciences (40669)
- Civil and Environmental Engineering (40085)
- Electrical and Computer Engineering (37176)
- Business (34135)
- History (33260)
- Higher Education (30829)
- Mechanical Engineering (30245)
- Communication (28660)
- Computer Engineering (25752)
- Library and Information Science (21723)
- Environmental Sciences (20575)
- United States History (18872)
- Mass Communication (17344)
- Materials Science and Engineering (16794)
- Journalism Studies (15623)
- Public Affairs, Public Policy and Public Administration (15461)
- Chemical Engineering (14264)
- Physics (14013)
- Operations Research, Systems Engineering and Industrial Engineering (13956)
- Chemistry (12816)
- Civil Engineering (11840)
- Earth Sciences (11748)
- Institution
-
- University of New Mexico (46820)
- University of Nebraska - Lincoln (29629)
- Missouri University of Science and Technology (29096)
- University of New Hampshire (26588)
- Purdue University (25422)
-
- California Polytechnic State University, San Luis Obispo (23544)
- University of Mississippi (22162)
- Utah State University (18536)
- San Jose State University (18477)
- University of South Florida (17197)
- University of Central Florida (14649)
- Murray State University (13870)
- University of Kentucky (12094)
- Louisiana State University (11944)
- Clemson University (11909)
- Brigham Young University (11653)
- University of Montana (10513)
- University of Dayton (10431)
- Singapore Management University (10089)
- Rochester Institute of Technology (10023)
- Wright State University (9639)
- New Jersey Institute of Technology (9616)
- Technological University Dublin (9204)
- Georgia Southern University (9184)
- Old Dominion University (9083)
- Air Force Institute of Technology (8797)
- TÜBİTAK (8713)
- Portland State University (8699)
- University of Texas at Arlington (8687)
- University of North Dakota (8603)
- Keyword
-
- Newspaper (25560)
- Student newspaper (10277)
- Spartan Daily (8718)
- Newspapers (8399)
- Engineering (5725)
-
- Higher education (5335)
- Education (5291)
- N.M. (5173)
- History (4933)
- Pennsylvania (4860)
- Newsletter (4797)
- Michigan (4751)
- Collegeville (4732)
- Humans (4485)
- Holland (4478)
- College student newspapers and periodicals (4463)
- Local newspapers (4447)
- Bowling Green State University (4352)
- Holland City News (4139)
- Machine learning (3897)
- New Mexico (3828)
- Faculty (3701)
- Student newspapers (3654)
- Las Vegas (3641)
- Undergraduate (3616)
- News (3609)
- Montgomery County (3437)
- Trappe (3427)
- BG News (3380)
- Students (3351)
- Publication Year
-
- 2026 (30381)
- 2025 (39945)
- 2024 (39346)
- 2023 (38767)
- 2022 (38578)
-
- 2021 (41182)
- 2020 (39205)
- 2019 (38589)
- 2018 (37683)
- 2017 (35512)
- 2016 (36002)
- 2015 (32485)
- 2014 (31772)
- 2013 (29935)
- 2012 (28617)
- 2011 (25179)
- 2010 (24329)
- 2009 (20824)
- 2008 (20160)
- 2007 (18564)
- 2006 (17232)
- 2005 (15487)
- 2004 (14594)
- 2003 (12491)
- 2002 (11865)
- 2001 (11060)
- 2000 (10484)
- 1999 (9574)
- 1998 (9446)
- 1997 (8763)
- Publication
-
- Theses and Dissertations (29689)
- Faculty Publications (12200)
- Electronic Theses and Dissertations (11610)
- Theses (11540)
- Spartan Daily (School of Journalism and Mass Communications) (8220)
-
- Daily Mississippian (all digitized issues) (7496)
- Research Collection School Of Computing and Information Systems (7050)
- Masters Theses (6588)
- Dissertations (6443)
- Walden Dissertations and Doctoral Studies (6401)
- Cal Poly Student Newspaper (6038)
- Santa Fe New Mexican, 1883-1913 (5669)
- Master's Theses (5237)
- Articles (5232)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (5007)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (4697)
- Faculty Scholarship (4340)
- Defensive Publications Series (4314)
- Graduate Theses and Dissertations (4302)
- USF Tampa Graduate Theses and Dissertations (4219)
- Doctoral Dissertations (4086)
- Library Philosophy and Practice (e-journal) (4029)
- Journal of System Simulation (3924)
- Montana Kaimin, 1898-present (3805)
- Electrical and Computer Engineering Faculty Research & Creative Works (3465)
- Publications (3421)
- BG News (Student Newspaper) (3412)
- Nebraska Tractor Tests (3402)
- The Murray Ledger & Times (3399)
- The Mayfield Messenger (3381)
- Publication Type
Articles 67051 - 67080 of 1114062
Full-Text Articles in Entire DC Network
The Sky’S Not The Limit: Navigating Starlink’S Impact On Global Connectivity And Regulation, Michael N. Hillebrand
The Sky’S Not The Limit: Navigating Starlink’S Impact On Global Connectivity And Regulation, Michael N. Hillebrand
SMU Science and Technology Law Review
This case note examines the governance implications arising from the onset of accelerated satellite internet expansion and explores potential regulatory solutions for effective governmental oversight. Due to the interconnected nature of the internet and its global network, international organizations and treaties play a crucial role in content and data regulation, and rapid technological evolution presents increasing difficulties for these regulatory frameworks to keep pace. These challenges are particularly evident in satellite-based broadband internet services, with SpaceX’s Starlink emerging as the most prominent and currently relevant service in this domain. Proponents of this technology emphasize its ability to provide internet access …
Fake Parts, Real Threats: Combating The Infiltration Of Counterfeit Parts In The Aviation Industry, Jennifer Su
Fake Parts, Real Threats: Combating The Infiltration Of Counterfeit Parts In The Aviation Industry, Jennifer Su
Journal of Air Law and Commerce
This Comment addresses the historic and current-day issue of counterfeit aircraft parts in the aviation industry. Counterfeit parts—also known as fake parts, bogus parts, unapproved parts, and suspected unapproved parts (SUPs)—are any parts that do not conform to the U.S. Federal Aviation Administration’s (FAA) standards and regulations. Given the lackluster availability of public information and coverage over the issue, this Comment aims to bring more attention to the very real threat of fake aircraft parts.
From the beginning of U.S. commercial aviation and the creation of regulations governing aircraft designs and parts, counterfeit parts have plagued the aviation industry. Although …
Exploring Undergraduate Understanding And Learning Of Catholic Social Teaching In Catholic Higher Education, Kenny Van Tilburg
Exploring Undergraduate Understanding And Learning Of Catholic Social Teaching In Catholic Higher Education, Kenny Van Tilburg
Dissertations
Since the Second Vatican Council in the mid-1960s, Catholic higher education (CHE) has wrestled with its Catholic identity in a changing landscape and changing world (Gallin, 1996, 2000; Gleason, 1995; Morey & Piderit, 2006). A big component of this identity-recognition process is the continued evolution and inclusion of Catholic social teaching (CST) in the educational approach of CHE. Despite its importance, much evidence has suggested CST is underwhelmingly present in the education of contemporary CHE (Beyer, 2021; Galligan-Stierle, 2014; Hudson et al., 2018; Nickerson & Dammer, 2018; Reed-Bouley, 2016; Sullivan & Pagnucco, 2014; United States Conference of Catholic Bishops [USCCB], …
Judge–Scholar Collaboration And The Second Amendment, Andrew Willinger, Eric Ruben
Judge–Scholar Collaboration And The Second Amendment, Andrew Willinger, Eric Ruben
SMU Law Review
Legal scholarship is overly abstract and theoretical, making it unhelpful to judges and lawyers. That, at least, is the classic critique from the bench. When it comes to the Second Amendment, however, a different pattern has emerged: judges consistently cite law review articles and look to the academy for guidance. Most recently, in United States v. Rahimi, some Justices went further, implicitly inviting more scholarly work to help the Court answer open questions raised by its novel methodological approach to the Second Amendment. This Article explores this aberrant trend.
We raise several explanations for the distinctive scholarly role in …
John C. West Papers - Accession 1400, John Carl West Sr.
John C. West Papers - Accession 1400, John Carl West Sr.
Manuscript Collection
This collection consists of photographs, scrapbooks, framed items, awards and certificates, videotapes, audiotapes, and other memorabilia pertaining to former governor of South Carolina (1971-1975) and ambassador to Saudi Arabia (1977-1981) John C. West. John Carl West, Sr. (1922-2004) married 1943 Winthrop Alumna Lois Rhame West (1921-2014) and the Lois Rhame West Health, Physical Education, and Wellness Center was named in her honor. John West, as South Carolina Governor, played a prominent role in Winthrop’s move to coeducation and signed the bill confirming Winthrop’s transition in 1974.
Digital Zines As Mental And Sexual Health Communication Tools For Latina Teens: Format And Content Acceptability And Initial Findings, Jenn M. Lilly, D'Andrah Almanzar, Susan R. Pace, Dante D. Bryant
Digital Zines As Mental And Sexual Health Communication Tools For Latina Teens: Format And Content Acceptability And Initial Findings, Jenn M. Lilly, D'Andrah Almanzar, Susan R. Pace, Dante D. Bryant
Social Service Faculty Publications
Recognizing the potential of digital zines (defined as selfpublished,
online publications combining artwork and
text) as culturally tailored health communication tools,
this article examines the acceptability and impacts of two
digital zines about mental and sexual health created by
Latina young people for Latina teens as a health communication
strategy. We conducted an anonymous online
survey completed by Latina teens who read the zines (32
for sexual health and 33 for mental health). Data analysis
aimed to explore, summarize, and interpret the collected
data using an artificial intelligence (AI)-enhanced
approach. Survey participants found the zine format and
content acceptable and …
Navigating Together: The Conav Testbed And Framework For Benchmarking Cooperative Localization, Rohith Boyinine, Jayanth Ammapalli, Anusna Chakraborty, Rajnikant Sharma, Kevin Brink, Clark N. Taylor
Navigating Together: The Conav Testbed And Framework For Benchmarking Cooperative Localization, Rohith Boyinine, Jayanth Ammapalli, Anusna Chakraborty, Rajnikant Sharma, Kevin Brink, Clark N. Taylor
Faculty Publications
This paper presents CoNaV, a comprehensive framework for creating a multi-vehicle cooperative localization (CL) testbed designed to support the benchmarking, development, and deployment of cooperative navigation algorithms. Given the essential role of CL in improving localization accuracy for both defense and civilian applications, CoNaV provides a robust environment for rigorously validating algorithms under real-world conditions. By establishing a benchmark for CL algorithms, CoNaV lays a foundation for advancing research into more sophisticated and distributed CL solutions. This framework highlights the potential of cooperative navigation to enhance multi-vehicle operations and offers a scalable, practical approach for future developments in CL technology.
Revised Final Multi-Pathway Residential Metals Abatement Program Plan, Atlantic Richfield Company, Butte Silver Bow
Revised Final Multi-Pathway Residential Metals Abatement Program Plan, Atlantic Richfield Company, Butte Silver Bow
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Fault Box Modeling Of Dip Slip Faults: A Framework For Fault Box Design And Future Studies, Hailey Pressnell
Fault Box Modeling Of Dip Slip Faults: A Framework For Fault Box Design And Future Studies, Hailey Pressnell
Master's Theses
The behavior of soils during surface fault rupture is a serious concern in the planning and design of infrastructure that may be located within or near a fault zone. Challenges associated with developing mitigation measures for surface fault rupture include the uncertainty of fault rupture and the variability of fault behavior. Current analytical procedures define surface fault rupture according to the type of fault movement (strike slip, normal or reverse), the amount of displacement on the fault, and the mechanics of the material overlying the fault. The purpose of this thesis is to reconfirm analytical solutions and gain a better …
Analyzing The Safety Effects Of Edge Lane Roads For Motor Vehicle Users, John Yang
Analyzing The Safety Effects Of Edge Lane Roads For Motor Vehicle Users, John Yang
Master's Theses
This thesis builds upon a prior study that analyzed the safety effects of Edge Lane Roads (ELRs) within the U.S. context, addressing gaps related to collision, traffic volume, and speed data. An ELR is a roadway configuration that accommodates two-way automobile traffic within a single center lane while providing edge lanes for vulnerable road users (VRUs), i.e., bicyclists or pedestrians. Although the concept of a single shared lane for opposing traffic often raises safety concerns among the public, ELRs have demonstrated potential to control speeds, optimize roadway space, and improve traffic operations on low-volume roads.
To evaluate safety outcomes, this …
Digital Twins For Flexible Manufacturing, Drew Brandon Sander
Digital Twins For Flexible Manufacturing, Drew Brandon Sander
Theses and Dissertations
With the establishment of Digital Twins as an enabling technology for Industry 4.0, it is time to transition from the previous foundations to works that implement and highlight the capabilities Digital Twins present. The Industry 4.0 paradigm has recentered the focus on customizability, leading to reemerging goals of flexibility within manufacturing. Empowered through new cyber-physical systems, new enabling technologies are driving the revolution. To identify how Digital Twins as an enabling technology contribute to flexibility within manufacturing, a comprehensive investigation is conducted along with a detailed case study. A systematic literature review is conducted to analyze quality Digital Twin implementations …
258th Annual Cornish Report Of The Selectmen And Other Town Officers For The Year Ending December 31, 2024, Cornish, New Hampshire, Cornish Town Representatives
258th Annual Cornish Report Of The Selectmen And Other Town Officers For The Year Ending December 31, 2024, Cornish, New Hampshire, Cornish Town Representatives
Cornish, NH Annual Reports
This is an annual report containing vital statistics for a town/city in the state of New Hampshire.
Long-Term Assessment Of The Morphological Behavior Of The Beaches North Of Sebastian Inlet, Florida, Aidan O'Gorman
Long-Term Assessment Of The Morphological Behavior Of The Beaches North Of Sebastian Inlet, Florida, Aidan O'Gorman
UNF Graduate Theses and Dissertations
The morphological behavior of the beaches north of Sebastian Inlet, Florida is investigated by applying Empirical Orthogonal Function (EOF) analyses to a series of beach surveys conducted semi-annually (winter and summer) over a period of fifteen years (2005-2019), with the primary objectives being to 1) determine the extent to which the inlet’s influence to the north typically fluctuates on a short-term basis (e.g. annually), and 2) identify any long-term trends of accretion or erosion that might exist. Each survey is comprised of thirty-one cross-shore profiles that are referenced to permanently installed range monuments (“R-monuments”) that are spaced nominally 305 …
Assessment Of Surface Area Application Ratios For Beach Sand Treated Via Surface Percolated Micp-Bioslurry For Erosion Mitigation, Connor J. Marlin
Assessment Of Surface Area Application Ratios For Beach Sand Treated Via Surface Percolated Micp-Bioslurry For Erosion Mitigation, Connor J. Marlin
UNF Graduate Theses and Dissertations
Rapid shoreline erosion associated with sea-level rise is an ongoing threat to coastal infrastructure. Traditional stabilization techniques, such as revetments, seawalls, and periodic nourishment, often prove costly, ecologically disruptive, or provide only temporary protection. Microbially Induced Calcite Precipitation (MICP) and its operational variant, bioslurry, present a biologically inspired alternative capable of forming a cemented surface crust that reduces soil erodibility. Previous laboratory studies typically prescribed a solution dosage as a percentage of pore volume (%PV). While geotechnically sound, this metric is poorly suited to field deployment across a large area. This thesis evaluates surface-area-based dosing (L/m²) as the primary dosage …
Dielectric Performance Of Fused Filament Fabricated Ultem 9085 For Naval Radome Application, Carson Rogers
Dielectric Performance Of Fused Filament Fabricated Ultem 9085 For Naval Radome Application, Carson Rogers
UNF Graduate Theses and Dissertations
ULTEM 9085 is a high-performance thermoplastic used in the fused filament fabrication (FFF) additive manufacturing process. It has found use in applications where mechanical strength, chemical integrity, and thermal stability are of paramount importance. In this thesis, the effects of process parameters, annealing, and weathering on the mechanical and dielectric properties of FFF ULTEM 9085 have been investigated.
The first part reviews existing research on how printing parameters such as nozzle temperature, chamber temperature, print speed, infill, and layer height affect the mechanical performance of FFF ULTEM 9085. Data from the manufacturer of commonly used ULTEM 9085 filament, Stratasys, has …
Improving Queries To Retrieval-Augmented Generation Ai Tools By Inferring The Sources Of Bad Results, Julie Arendt
Improving Queries To Retrieval-Augmented Generation Ai Tools By Inferring The Sources Of Bad Results, Julie Arendt
VCU Libraries Faculty and Staff Presentations
Since ChatGPT’s wide release, businesses have rushed into expanding their use of generative artificial intelligence. Information providers, including suppliers of library databases and integrated library systems, are joining the trend, with many products combining the verifiability of direct source access and citation with the conversational answers produced through large language models. Retrieval-augmented generation is a common technique that overlays search results with text extracted and processed through generative artificial intelligence. This poster provides an overview of retrieval-augmented generation and summarizes ways that it can produce errors. Strategies for improving results, based on those error modes are suggested.
Distribution Of Supplemental Educational On Pharmacology To Assist Mental Health Technicians On The Behavioral Health Unit In Leading Group Therapy Sessions: A Quality Improvement Project, Bree T. Mastromarino
Distribution Of Supplemental Educational On Pharmacology To Assist Mental Health Technicians On The Behavioral Health Unit In Leading Group Therapy Sessions: A Quality Improvement Project, Bree T. Mastromarino
Master's Theses and Capstones
Background
Staff within the microsystem strive to provide quality care to patients experiencing acute mental health crises in hopes of stabilizing their condition, allowing them to function safely and appropriately among others. This will hopefully lead to eventual rehabilitation back into society. The main technique used in this microsystem for the rehabilitation of patients is providing group therapy (GT) sessions. These sessions teach healthy coping mechanisms and encourage internal reflection on triggers that could be contributing to emotional instability.
Local Problem
Recently, the leadership team has made the decision that Mental Health Technicians (MHTs) and social workers will lead the …
A Quality Improvement Project: Increasing Nurse Satisfaction With Patient Educational Material Related To Pain Management Options During Labor, Madison Grant
Master's Theses and Capstones
BACKGROUND:
Pain management is a large portion of what nurses manage during the patient’s time on the labor and delivery unit. The primary forms of pain management that is available to women during this time includes epidurals, nitrous oxide, stadol/diphenhydramine, and nonpharmacological options such as breathing techniques. It is essential that patients are aware of all pain management options prior to entering the unit for delivery, however sometimes nurses have to help to close the educational gap.
LOCAL PROBLEM:
Within the microsystem, it was acknowledged that many patients lacked the education of their pain management options prior to delivery which …
Improving Intensive Care Unit Nurses' Knowledge And Confidence In Performing Effective Spontaneous Awakening Trials: A Quality Improvement Project, Sophia T. Merry-Carreiro
Improving Intensive Care Unit Nurses' Knowledge And Confidence In Performing Effective Spontaneous Awakening Trials: A Quality Improvement Project, Sophia T. Merry-Carreiro
Master's Theses and Capstones
Abstract
BACKGROUND
Mechanically ventilated ICU patents often require sedation for comfort and ventilator compliance. However, oversedation is linked to negative outcomes such as delirium, prolonged ventilation, and increased duration of ICU stay. Current best practices now support the use of daily sedation interruptions such as Spontaneous Awakening Trials (SATs). Despite these recommendations, implementation of SATs remain inconsistent and suboptimal.
LOCAL PROBLEM:
Within the ICU in a northern new England hospital, there was a need to improve nurse confidence and knowledge in SATs practices through staff education.
METHODS:
Using the Plan-Do-Study-Act (PDSA) model, a quality improvement project was developed to improve …
Enhancing Triage Accuracy And Nursing Confidence Of The Emergency Severity Index To Improve The Effectiveness Of Triage Through Targeted Education: An Evidence-Based Quality Improvement Project, Mia K. Saucedo
Master's Theses and Capstones
Background: The Emergency Severity Index system is a standardized triage scoring guide used by emergency department nurses to efficiently assess patients based on severity and projected recourse needs. Studies have found that knowledge and confidence gaps among nurses may lead to improper triage score, leading to the misallocated spread of resources and longer wait times, increasing rates of morbidity and mortality. Early recognition of patient severity is vital for providing proficient patient care and improving patient outcomes and increased education is needed to improve this gap in nursing knowledge and confidence.
Local Problem: At a small, critical care access center …
Directing Patient Hand Hygiene Before Meals In The Icu: A Quality Improvement Project To Enhance Patient Safety, Nicholas Davini
Directing Patient Hand Hygiene Before Meals In The Icu: A Quality Improvement Project To Enhance Patient Safety, Nicholas Davini
Master's Theses and Capstones
BACKGROUND:
Hospital-acquired infections (HAIs) are a major problem in healthcare, increasing patient morbidity, mortality, and costs. While staff hand hygiene is a well-established infection control measure, less attention is paid to patient hand hygiene (PHH) despite CDC recommendations.
LOCAL PROBLEM:
An intensive care unit (ICU) in northeastern Massachusetts had no formal policy for patient hand hygiene, and hospital leadership expressed support for enhancing infection control practices.
METHODS:
Using the Plan-Do-Study-Act model, a quality improvement project was implemented to encourage PHH before meals. Baseline PHH rates were collected through observation. The intervention involved registered nurses (RNs) directing patients to use hand …
Educating Staff On Effective Ways To Improve Medication Discharge Instructions In Emergency Departments (Ed): A Quality Improvement Project, Isabelle L. Kuhn
Educating Staff On Effective Ways To Improve Medication Discharge Instructions In Emergency Departments (Ed): A Quality Improvement Project, Isabelle L. Kuhn
Master's Theses and Capstones
Background: Emergency Departments (EDs) serve a vital role in treating acute conditions, yet they face challenges in ensuring patients understand discharge instructions, particularly those related to medications. Approximately 70% of ED patients demonstrate deficits in at least one discharge domain, including medication understanding. Limited health literacy, time constraints, and rushed environments contribute to these gaps. Improving discharge communication is critical to reduce medication errors and prevent avoidable readmissions.
Local Problem: In a Northern New England ED, an assessment of the microsystem highlighted that patients often struggled to understand medication discharge information, increasing the risk of non-adherence and readmission. …
Optimizing Surgical Count Accuracy And Efficiency Through Enhanced Operating Room Communication To Promote Patient Safety: A Quality Improvement Project, Jessica L. Limbocker
Optimizing Surgical Count Accuracy And Efficiency Through Enhanced Operating Room Communication To Promote Patient Safety: A Quality Improvement Project, Jessica L. Limbocker
Master's Theses and Capstones
Abstract
Background: Retained surgical items (RSIs) are classified as “never events” because they are preventable and pose significant risks to patient safety. This quality improvement (QI) project aimed to reduce the risk of RSIs, particularly during Cesarean sections by identifying gaps in surgical count practices and implementing targeted interventions.
Local Problem: At the project site, baseline assessments revealed gaps in surgical count practices. These included inconsistent documentation, absence of formal education on count procedures, and communication barriers among the intraoperative team—all contributing to increased risk of RSIs.
Methods: This QI project implemented a multi-faceted intervention to enhance …
Improving The Effectiveness Of Post-Anesthesia Care Unit Transitions: A Quality Improvement Initiative Using A Standardized Nurse Handoff Report Sheet, Myra Mcauley
Master's Theses and Capstones
Background: Effective communication during patient handoff in the post-anesthesia care unit (PACU) is essential to ensuring patient safety and continuity of care. Unstructured or inconsistent handoff processes can lead to information omissions and care delays.
Methods: This quality improvement project implemented a structured nurse-to-nurse handoff report tool in the PACU. A pre- and post-intervention survey design was used to assess nurses’ perceptions of handoff clarity, completeness, and satisfaction. Educational sessions supported implementation.
Results: Pre-intervention survey data revealed dissatisfaction with the current handoff process, citing frequent information gaps. Following implementation of the structured tool, post-survey results showed improved communication clarity, increased …
Oriented Surface Immobilization Of Antibodies Using Enzyme-Mediated Site-Specific Biotinylation For Enhanced Antigen-Binding Capacity, Emily Beitello, Kwame Osei, Trent Kobulnicky, Faith Breausche, Jon A. Friesen, Jeremy D. Driskell
Oriented Surface Immobilization Of Antibodies Using Enzyme-Mediated Site-Specific Biotinylation For Enhanced Antigen-Binding Capacity, Emily Beitello, Kwame Osei, Trent Kobulnicky, Faith Breausche, Jon A. Friesen, Jeremy D. Driskell
Faculty Publications – Chemistry
The effectiveness of surface-immobilized antibodies is often diminished by improper antibody orientation and limited stability, impeding the analytical performance of biosensors. Here, we report a novel enzyme-mediated strategy to biotinylate the Fc region of an anti-horseradish peroxidase (anti-HRP) antibody with site-specificity that enables oriented immobilization on a streptavidin-functionalized surface. Microbial transglutaminase (mTG) catalyzes the covalent coupling between the amine functional group on a biotin analogue (NH2-PEG4-biotin) and the side chain of a privileged glutamine residue (Q295) located on the heavy chain Fc region of IgG antibodies. For comparison, an anti-HRP antibody was biotinylated using an amine-reactive …
Synthesis Of Alkyl Substituted Carbatripyrrins And Their Application To The Preparation Of Carbaporphyrins And Oxacarbaporphyrins, Ian A. Mclauchlan, Bethany K.X. Overbey, Tyler J. Smolczyk, John J. Woods, Timothy D. Lash
Synthesis Of Alkyl Substituted Carbatripyrrins And Their Application To The Preparation Of Carbaporphyrins And Oxacarbaporphyrins, Ian A. Mclauchlan, Bethany K.X. Overbey, Tyler J. Smolczyk, John J. Woods, Timothy D. Lash
Faculty Publications – Chemistry
Unsubstituted carbatripyrrins have previously been shown to be useful intermediates in the synthesis of benzocarbaporphyrins and related core-modified analogues. However, the absence of substituents often resulted in the formation of poorly soluble products. In this study, four examples alkyl substituted carbatripyrrins were constructed by base-catalyzed condensation of dihydrofulvenes with pyrrole aldehydes. Further reaction with a pyrrole dialdehyde in the presence of trifluoroacetic acid afforded a series of carbaporphyrins, while reactions with 2,5-furandicarboxaldehyde generated oxacarbaporphyrins. These results demonstrate that alkyl substituted carbatripyrrins are promising precursors to new carbaporphyrinoid structures.
Emi Mitigation, Material Characterization, Transformer Equivalent Circuit Modeling, Reza Vahdani
Emi Mitigation, Material Characterization, Transformer Equivalent Circuit Modeling, Reza Vahdani
Masters Theses
Modern high-frequency electronic systems demand precise characterization and modeling techniques to ensure signal integrity and electromagnetic compatibility. This thesis presents three core studies focused on real-world challenges in high-speed and power electronics: EMI mitigation using 3D printed absorbers, wideband liquid dielectric characterization, and accurate transformer modeling.
The first study demonstrates a targeted approach to mitigating electromagnetic interference (EMI) in a commercial router. By using holography imaging to identify radiation hotspots, custom absorber structures were designed with commercially available materials, fabricated via 3D printing, and applied directly to emission sources. Radiated emission tests in a reverberation chamber showed up to 9 …
Revisiting An Old Argument: Wilbur Urban And Bertram Morris Vs. Percy Hughes And A. H. Johnson On Alfred North Whitehead’S Reductionism, Michael A. Flannery
Revisiting An Old Argument: Wilbur Urban And Bertram Morris Vs. Percy Hughes And A. H. Johnson On Alfred North Whitehead’S Reductionism, Michael A. Flannery
Libraries Professional Work
No abstract provided.
Optimal Data Splitting Methods, Sujay Mudalgi
Optimal Data Splitting Methods, Sujay Mudalgi
Theses and Dissertations
In predictive modeling, effective data splitting is crucial for creating statistically representative training and validation sets. The state-of-the-art data splitting methods are based on minimizing the energy distance between the split subsets. However, there are a number of limitations in the existing methods, which this dissertation aims to address. First, the existing methods were computationally inefficient. Thus, Chapter 2 proposes a method to scale up these approaches for big data. Here, we introduce scalable Twinning (s-Twinning), which significantly improves the execution speed of data splitting without sacrificing accuracy. Second, the existing methods did not consider the predictive relationship in the …
Characterization Of Nanoplastic-Induced Exacerbation Of Asthmatic Pathophysiology In A Murine In Vivo Model, Keith Li
Theses and Dissertations
As global plastic production increases, so does the environmental and biological presence of nanoplastics (NPs), raising growing concerns about their potential impact on human health. These particles have been detected in various organs, including the lungs, yet their role in respiratory inflammation remains largely unexplored. Emerging evidence suggests that NP exposure may influence immune responses in the lungs, particularly in individuals with preexisting conditions such as asthma. However, the specific ways in which these particles interact with allergen driven inflammation are still unclear.
In this study, a murine model of allergic airway inflammation was used to investigate how surface modified …