Digital Commons Network^™

Rubber Foot Speaker, Hp Inc

Defensive Publications Series

This disclosure proposed on repositioning the speaker from internal (inside the chassis) to the external surface. The design incorporates the use of rubber foot with speaker into a single component.  The intention of this idea is to reduce the impact of vibration from the speakers and eliminating the rattling issue when installed internally. The idea also promotes sound quality, flexibility and cost reduction.

Intent-Driven Orchestration For Enterprise Cyber-Physical Systems: Bridging Probabilistic Planning And Deterministic Actuation, Hp Inc

Defensive Publications Series

This disclosure describes an intent-driven orchestration architecture for enterprise cyber-physical systems that bridges generative, probabilistic, or agentic planning and deterministic device actuation. A non-executing, domain-aware planner converts high-level intent into a candidate graph of typed, idempotent Atomic Tool calls, but does not invoke tools or control devices. A deterministic orchestrator executes only graphs that pass four deterministic validation gates covering schema, governance, semantic correctness, and Device Twin-based simulation. Device Twins provide cached state for deterministic simulation, guard evaluation, binding resolution, and observability, but are not consumed by the Planner and are not authoritative for write-path success. Atomic Tools perform semantic …

Dynamic Exponent-Mantissa Repurposing For Adaptive Microscaling (Demr-Am) Architecture, N/A

Defensive Publications Series

This publication details a hardware architecture and data processing methodology for dynamic exponent and mantissa repurposing, tailored to facilitate adaptive microscaling within machine learning accelerators. The described methodology addresses the quantization errors and memory bandwidth constraints that frequently emerge during the deployment of large-scale artificial intelligence models. By dynamically repurposing redundant exponent bits into additional mantissa bits specifically for outlier values within a given tensor block, the system dramatically enhances numerical precision without expanding the core memory footprint of the data block. A dedicated hardware decoder can be positioned immediately prior to a dot-product engine to re-route electrical signals and …

Agentic Knowledge Graph Engine With Continuous Evolution And Hybrid Semantic-Structural Embeddings For Intelligent Data Extraction, Knowledge Creation, And Retrieval, Hp Inc

Defensive Publications Series

An Agentic Knowledge Graph Engine (AKGE) is disclosed that provides a complete, continuously evolving knowledge lifecycle managed by a multi-agent autonomous architecture. The system comprises a data extraction layer receiving heterogeneous input sources, a schema-enforced knowledge graph storage layer with native temporal versioning and audit lineage, a hybrid embedding module fusing semantic, structural, contextual, and schema-constrained representations into dynamically updated entity embeddings, a continuous evolution engine responding to event triggers including query failure, embedding drift, conflict detection, and new data arrival, and a hybrid retrieval engine combining multi-hop graph traversal with approximate nearest-neighbor vector search. A specialized multi-agent ensemble — …

System And Method For Structured Queue Folder Management Of Print Jobs, Hp Inc

Defensive Publications Series

This disclosure presents a system and method for managing print queues as a persistent, hierarchical structure of folders, subfolders, and job records within production printing environments. Unlike conventional flat-list queue models, the disclosed approach preserves semantic relationships among related print jobs throughout the entire execution lifecycle, enabling group-level operations—such as print, pause, resume, cancel, and prioritize—to be applied coherently to collections of jobs without requiring individual job manipulation.

A central queue manager maintains a hierarchical model composed of folder nodes, subfolder nodes, and job nodes, each carrying metadata such as priority, state, sequencing policy, media requirements, and device constraints. A …

Cultivating Civility: A Multicomponent Approach To Reducing Workplace Incivility In An Assisted Living Facility, Sanam Bral, Kaylyn Chang, Catherine Dinh, Sanjil Kumar, Truc Mai Moon

Master's Projects and Capstones

Workplace incivility remains a common challenge in healthcare, negatively affecting communication, staff well-being, and the quality and safety of resident care. Baseline survey findings from a faith-based assisted living facility in Southern California identified concerns related to workplace incivility, psychological safety, and gaps in staff knowledge of available reporting resources. This project aimed to reduce workplace incivility by improving staff knowledge and recognition of uncivil behaviors, with a target of at least 90% staff training attendance among nursing, assistive nursing, and medical technicians, and 80% attendee-reported high confidence level (agree or strongly agree) in recognizing incivility and understanding reporting options. …

Imsa Summer Symposium 2026, Student Inquiry And Research (Sir)

Summer Symposium

For nearly four decades, IMSA has worked to advance the human condition through educational innovation. The Summer Symposium is our annual showcase for the research projects that were conducted in IMSA’s experiential learning programs between May and August. These programs include Student Inquiry and Research (SIR), IN2 Business Internships, and the Student Research and Experiential Learning Opportunity (SRELO) program. For the first time, we are also excited to welcome IMSA Research, Inquiry Skills, and Experimentation (RISE) students to present at the Summer Symposium.

Cover Design

Luke Berryman

Fostering Future Difference-Makers: The Integration Of Leadership Training In Law Schools, Leah Teague

Journal of Legal Education

No abstract provided.

Professional Identity Formation As Theory And As Practice For The Education Of A Lawyer, Louis D. Bilionis, Neil W. Hamilton

Journal of Legal Education

No abstract provided.

Profiling Arbutin As A Potent Cholinesterase And Gsk-3Β Inhibitor And Evaluating Its Cytotoxicity In Sh-Sy5y Cells For Alzheimer’S Disease Therapy, Shirin Tarbiat, Tuğba Bal, Deni̇z Gülmez

Turkish Journal of Biology

Background/aim: Alzheimer’s disease (AD) is a neurodegenerative disorder linked to cognitive decline and memory loss, marked by hyperphosphorylated tau tangles and decreased acetylcholine levels, which are affected by acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity. Glycogen synthase kinase-3 beta (GSK-3β) also plays a role in AD through abnormal activation. In this study, the potential of β-arbutin to inhibit cholinesterases and GSK-3β was investigated, utilizing in vitro assays, cytotoxicity analysis, and molecular docking simulations to explore its therapeutic implications.

Materials and methods: Ellman’s technique was used to test the inhibitory effects of arbutin on cholinesterase enzymes. An ATP-Glo luminescent assay kit was …

Probiotic Intervention In Colorectal Cancer: The Cytotoxic And Apoptotic Potential Of Lactobacillus Cell-Free Supernatants, Bahar Yilmaz, Berna Erdal

Turkish Journal of Biology

Background/aim: Failures in the treatment of colorectal cancer (CRC) have increased scientific interest in the potential of the bioactive compounds contained in cell-free supernatants (CFSs) obtained from probiotic bacteria for cancer treatment. The aim in this study was to investigate the effects of CFSs obtained from Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus) and Lactobacillus paracasei subsp. paracasei (L. paracasei) on colorectal cancer cell lines (HT-29 and Caco-2) and a healthy colon epithelial cell line (CCD841 CoN).

Materials and methods: Cytotoxic effects on the cell lines were determined by MTT assay. In line with the IC50 values obtained, morphological changes were …

Cover And Contents

Turkish Journal of Biology

No abstract provided.

Discovery And Functional Characterization Of Novel Programmed Death-Ligand 1 Monoclonal Antibodies, Nurşah Ersezen, Mai̇de Şeker, Arzu Aysan, Durmuş Akdoğan, Mehmet Ender Avci, Asli Kurden Pekmezci̇, Si̇bel Kalyoncu Uzunlar, Mehmet İnan, Tamer Yağci

Turkish Journal of Biology

Background/aim: Targeted therapies with monoclonal antibodies provide cancer patients with better prognosis and diseasefree survival. The blockade of immune checkpoints, including programmed cell death protein-1 (PD-1) and its ligand PD-L1, with monoclonal antibodies may boost immune responses against tumors and is regarded as an effective strategy in cancer immunotherapy. We describe the generation of anti-PD-L1 monoclonal antibodies with high affinity and specificity, and we assess their potential for therapeutic use in cancer.

Materials and methods: Hybridomas were selected for PD-L1 specificity and cross-reactivity with other immune checkpoint proteins and PD-L1 orthologs using indirect ELISA. Immunofluorescence and Western blotting assays were …

Electronic Structure Discretization And Compression Using Diagonal Basis Sets, Casey Lee Dowdle

Dartmouth College Ph.D Dissertations

Numerically solving the electronic structure problem is a fundamentally difficult problem due to the exponential growth in the dimension of the Hilbert space as the system size increases. In order to solve problems at a chemically relevant accuracy, both the choice of basis set and numerical method are important factors that are intrinsically connected.

In this thesis, we study the discretization and resulting compression of electronic Hamiltonians using diagonal basis sets. A diagonal basis set approximately diagonalizes the matrix and tensor representations of the one- and two-body potentials. This can reduce storage, simplify matrix-vector products, and lower the complexity of …

Imsa Summer Symposium 2026, Student Inquiry And Research(Sir)

IMSAloquium Event Booklets

For nearly four decades, IMSA has worked to advance the human condition through educational innovation. The Summer Symposium is our annual showcase for the research projects that were conducted in IMSA’s experiential learning programs between May and August. These programs include Student Inquiry and Research (SIR), IN2 Business Internships, and the Student Research and Experiential Learning Opportunity (SRELO) program. For the first time, we are also excited to welcome IMSA Research, Inquiry Skills, and Experimentation (RISE) students to present at the Summer Symposium.

Zineth, Colin Wilcox

Theses

This thesis asks whether a brand can generate real engagement without surrendering to an algorithm, and whether web design can recover the color, mystery, and sense of discovery it traded away as the internet corporatized. Daily internet use has risen every year on record, yet the spaces users inhabit have flattened into grey buttons and endless feeds. This question is answered through Zineth, a hybrid brand universe told across three coordinated forms: a Risograph-printed zine, a dense and layered website, and limited clothing drops. The zine operates as a key. Codes printed in its pages unlock gated areas of the …

Mechanical Characterization Of Stereolithography 3d Printing Resins Using Tensile And Flexural Testing, Oliver Stitt

Mechanical Engineering and Materials Science Independent Study

This study characterized and compared Clear V5 and Tough 1500 Resin V2 specimens printed on a Formlabs Form 4 SLA resin printer using tensile and flexural mechanical testing. Tensile testing was based on ASTM D638-14 using Type IV specimen geometry, and flexural testing was based on ASTM D790-17 using three-point bending geometry. Clear V5 produced a mean tensile modulus of 1953.5 MPa and flexural modulus of 1479.1 MPa, compared with 1328.0 MPa and 1103.9 MPa for Tough 1500. Clear V5 also reached the higher maximum engineering stress in tension, while Tough 1500 showed a more compliant response. The results were …

Rickettsia Africae Discovered In A Short-Term Urban Traveller To South Africa: A Case Report, Zunairah Sikder

Binghamton University Undergraduate Journal

Rickettsia Africae is a pathogen that causes African tick-bite fever (ATBF). Transmission typically occurs from ticks within the Central and South African regions. Previous studies suggested that ATBF is not uncommon amongst travelers to rural sub-Saharan Africa, especially during the rainy months of November through April. However, this case report highlights a woman who contracted ATBF in novel conditions. The 70-year-old woman reported travelling strictly to and from the local church and hotel for her four-day stay in July. After returning to America, the patient experienced extreme irritation on her arm, as well as complaints of headaches. She presented to …

A Message From The Managing Editor, Carissa Bayack

Binghamton University Undergraduate Journal

A message from the 2025-2026 Managing Editor of the Binghamton University Undergraduate Journal, Carissa Bayack.

For Weight Loss: Why Do Glp-1 Agonists Work, And How Can We Make Them Work Better?, Charlise Giang, Jieyi Meng, Mahmoud Ali Mohammad, Zhenqi Liu, Xinle Wu, Yi Zhu

Children’s Nutrition Research Center Staff Publications

Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have revolutionized the management of not only type 2 diabetes but also obesity. However, even with rapid therapeutic advances in GLP-1RAs, questions regarding the fundamental principles of GLP-1-mediated weight loss and the enhanced efficacy of next-generation therapies remain. In this comprehensive review article, we first examine the milestones of GLP-1, from its initial discovery and biological characterization to its successful translation into clinical therapy. Furthermore, this review highlights the latest clinical trial data, specifically HbA1c reduction, weight-loss efficacy, and safety profiles, while exploring current pipelines of major pharmaceutical companies. Additionally, we delineate the mechanistic …

Enhancing Algae Biofilm Quantity And Value Through Controlled Light Intensity For Treatment Of Municipal Anaerobic Digestor Effluent, Joshua D. Wintch, Ronald C. Sims

Biological Engineering Student Research

Rotating algae biofilm reactors (RABRs) have been shown to remove nutrients from wastewater and to cultivate algae for bioproducts. Another key variable in RABR technology for cultivating microalgae biomass is light intensity. The goal of this study was to address a gap in the design and operation of algae biofilm reactors by analyzing the effects of light intensity on biomass quality and quantity, chemical precipitation of phosphorus, and phosphorus uptake into biomass. This study utilized a triplicate laboratory-scale experiment with PAR intensities from 10 to 2000 µmol m⁻²·s⁻¹. Municipal wastewater anaerobic digester effluent (ADE) was utilized …

African American Gold Star Mothers: Race, Black Motherhood, Loyalism And European Superiority In The First World War, Giovanni Nickolette Gibbs

Masters Theses, 2020-current

This thesis examines the US government’s pilgrimages for Gold Star Mothers of the First World War. It focuses on the Jim-Crowing of black Gold Star Mothers. Through the analysis of archival records, letters, telegrams, newspaper articles, poems, and secondary literature, the thesis explores how two domineering forces, the National Association for the Advancement of Colored People and the federal government of the United States of America, captured dissension when seeking to send black Gold Star Mothers on segregated pilgrimages to Europe. The War Department’s announcement that the widows’ pilgrimages to Europe in the 1930s would be segregated caused a great …

Imsa Summer Symposium 2026, Student Inquiry And Reserach Reserach (Sir)

IMSAloquium Event Booklets

For nearly four decades, IMSA has worked to advance the human condition through educational innovation. The Summer Symposium is our annual showcase for the research projects that were conducted in IMSA’s experiential learning programs between May and August. These programs include Student Inquiry and Research (SIR), IN2 Business Internships, and the Student Research and Experiential Learning Opportunity (SRELO) program. For the first time, we are also excited to welcome IMSA Research, Inquiry Skills, and Experimentation (RISE) students to present at the Summer Symposium.

Cover Design

Luke Berryman

Calibrated Simulations For Dynamic Focusing Of Ultrasound Through The Temporal Window, Ehsan Dadgar-Kiani, Vibha Hebbale, Malachy W. Newman, Grace Attalla, John L. Alvarez, Suraya Dunsford, Kevin A. Caulfield, Cameron H. Good, Andrew D. Krystal, Leo P. Sugrue, Joline M. Fan, Elsa Fouragnan, Charles F. Caskey, Samuel Pichardo, Kim Butts Pauly, Keith R. Murphy

School of Psychology

Focused ultrasound can be delivered through the temporal window to modulate heterogeneously located brain areas. Acoustic simulations allow for safety assessments when dynamically targeting brain structures, but the mismatch between simulation and measured focal pressure can vary across the steerable range due to mechanically inaccurate assumptions made about the skull and transducer. Here, we describe efficient methods for simulation-measurement calibration using axisymmetric projections and sparse sampling across a 3D steerable subspace encompassing deep brain targets across 157 subjects. To address the simulation-reality mismatch in skull transmission, we used the measured and predicted pressure values through eight human temporal window fragments …

When Policy Meets Public Distrust: A Social Network Analysis On Indonesia's Mbg Program, Rizky Fauziah, Rehia Karenina Isabella Barus, Ressi Dwiana

JURNAL KOMUNIKASI INDONESIA

The Indonesian government program Free Nutritious Meal, locally abbreviated as MBG, launched in early 2025, has generated significant public controversy. Data from the Institute for Development of Economics and Finance (INDEF) indicate that, as of August 2025, approximately 4,000 students across Indonesia had reportedly suffered food poisoning associated with the program. This situation has fueled widespread public concern and contributed to declining trust in government. This study aims to analyze communication networks surrounding the MBG on the social media platform X. This study draws on Trust and Distrust Theory and employs a Social Network Analysis (SNA) approach to examine how …

Synthesis, Utilization And Biological Evaluation Of Β-Hairpin Peptides As Inhibitors Of Immune Checkpoints, Sarah Naylon

Electronic Theses and Dissertations 2020 - Present

Peptide therapeutics have emerged as promising alternatives to monoclonal antibodies because of their smaller size, improved tissue penetration, and synthetic versatility. Yet their broader application is often limited by poor structural stability, rapid clearance, and reduced target residence times. This dissertation describes the design, synthesis, structural characterization, and biological evaluation of β-hairpin peptides as inhibitors of immune checkpoints and as peptide vaccine scaffolds while developing strategies to overcome these limitations. At first a series of antibody-derived β-hairpin peptides (mimics of complementary determining region heavy-chain 3: CDR-H3s) as covalent inhibitors of the PD-1/PD-L1 immune checkpoint were investigated. Electrophilic warheads were incorporated …

Enhancing Tea Productivity Through Integrated Fertilization And Pruning Management: A Review, Intan Ratna Dewi Anjarsari, Murgayanti, Muhamad Kadapi, Syariful Mubarok, Uum Umiyati, Salsabilah, Alifatul Azmi, Afifah Putri Ramadhan, Trifani Hana Husniah, Rosita, Azkal Azkiya

Jurnal Kultivasi

Tea productivity is strongly influenced by agronomic management practices, particularly fertilization and pruning, which play critical roles in regulating plant growth, physiological performance, and shoot regeneration. This review aims to synthesize current scientific evidence on how integrated fertilization and pruning management can sustainably enhance tea productivity. A narrative review approach was employed by collecting and analyzing peer-reviewed articles published between 2015 and 2025 from reputable databases, including Google Scholar and major international journals. The review highlights that balanced fertilization strategies, combining inorganic, organic, and biofertilizers, significantly improve nutrient availability, photosynthetic efficiency, and shoot yield. Pruning, when properly timed and executed, …

Performance Of Dual-Form Terminalia Catappa Organic Fertilizers On Sweet Corn Yield And Economic Viability In Tropical Highlands, Stefina Liana Sari, Eso Solihin, Rahmat Budiarto

Jurnal Kultivasi

Recycling underutilized plant biomass into organic fertilizers underpins low-input cropping strategies, but liquid and solid formulations derived from a common feedstock have seldom been evaluated side by side under field conditions. This study aimed to (i) characterize the physicochemical properties and safety profile of a liquid organic fertilizer (LOF) and a crumb-type organic fertilizer (COF) co-produced from Terminalia catappa leaf compost, (ii) compare their effects on sweet corn growth and yield, (iii) determine relative agronomic effectiveness (RAE), and (iv) evaluate economic feasibility of the most promising organic–inorganic combinations. We produced LOF and COF through aerobic composting of Terminalia catappa leaves …

The Effectiveness Of Bacillus-Coated Npk Fertilizer On Broccoli Growth, Nutrient Status, Rhizosphere Bacillus Population, Yield, And Flower Quality, Betty Natalie Fitriatin, Rara Rahmatika Risanti, Reginawanti Hindersah, Fasa Aditya Hanindipto, Gita Bina Nugraha

Jurnal Kultivasi

Efforts to increase the availability of macronutrients in soil have relied on inorganic fertilization, particularly NPK fertilizers. However, global challenges in the fertilizer raw material supply chain, including price fluctuations and availability, are driving the need for more efficient and sustainable fertilizer alternatives. The field experiment was conducted in Baruajak, Lembang District, West Java, Indonesia, to evaluate the effectiveness of Bacillus-coated NPK fertilizer on broccoli (Brassica oleracea var. italica) growth, nutrient status, rhizosphere Bacillus population, yield, and flower quality. The experiment used a randomized complete block design with 15 fertilizer treatments and three replications. Treatments consisted of two coated NPK …

Genetic Diversity And Rhizome Flesh Color Variation Among Indonesian Turmeric (Curcuma Longa L.) Accession Revealed By Ssr Markers, Suseno Amien, Marisa Anggraeni, Agung Karuniawan, Noladhi Wicaksana

Jurnal Kultivasi

Turmeric (Curcuma longa L.) is a rhizomatous plant widely cultivated in Indonesia. Although recent studies have demonstrated that simple sequence repeat (SSR) markers are highly effective for assessing genetic diversity in Curcuma longa germplasm, most investigations have focused either on molecular diversity or breeding-oriented germplasm characterization traits of agronomic without integrating phenotypic commercial importance, particularly rhizome flesh color. The study was conducted from February to May 2026. This study aimed to evaluate the genetic diversity, phylogenetic relationships, and rhizome flesh color variation among Indonesian turmeric accessions collected by Plant Breeding Laboratory at the Faculty of Agriculture, Universitas Padjadjaran, and was …