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Articles 5251 - 5280 of 1192952
Full-Text Articles in Entire DC Network
Proposed Constitution Of The Southeastern Library Association, As Amended
Proposed Constitution Of The Southeastern Library Association, As Amended
The Southeastern Librarian
Proposed Constitution of the Southeastern Library Association, as Amended (Effective October 2026 following election)
Christianity, Gender Identity, Parents’ Rights: Book Censorship Discourse In Tennessee Communities, Janet Kesterson Isbell, Shawn Hinkel
Christianity, Gender Identity, Parents’ Rights: Book Censorship Discourse In Tennessee Communities, Janet Kesterson Isbell, Shawn Hinkel
The Southeastern Librarian
Hate and hostility toward the lesbian, gay, bisexual, transgender, queer+ (LGBTQ+) community and people of color, inflamed in recent years by political extremism and radical conservatism, have permeated many areas of society. One context where hostilities have emerged in the past decade is public debate surrounding book challenges, which prompted a yearlong investigation into the polarizing phenomenon of book censorship in the United States. After extensive reading of media reports from around the nation, the authors focused on public discourse related to book challenges in Tennessee public and school libraries, where debate was contentious, librarians were threatened, and the state’s …
A Dynamical Realization Of Holography In Cosmology From Hyperbolic General Relativity: Explicit Dimensional Reduction Via Curvature-Generated Shock Relaxation, Kiperman Jack
Physics Faculty Publications and Presentations
Holography asserts that the dynamics of a gravitational system may be determined by degrees of freedom associated with a lower-dimensional structure, rather than by independent volumetric variables. While this principle is well established in boundary-based constructions, its realization in cosmology has remained elusive due to the absence of fixed asymptotic boundaries. In this work, we present an explicit realization of holography in cosmology arising directly from the hyperbolic structure of general relativity. We show that the nonlinear evolution of the Einstein equations coupled to a scalar field generically produces a global control structure identified with the cosmological apparent horizon. By …
Laser Interstitial Thermal Therapy Enhances Bidirectional Blood-Brain Barrier Permeability In Glioblastoma, Ryan T Cleary, Yiwei Fu, David Giles, Jinyun Yuan, Diogo P Moniz Garcia, Danny Palmer, Rowland H Han, Timothy Woodiwiss, Alicia B Yang, Dimitrios Mathios, Hong Chen, Albert H Kim
Laser Interstitial Thermal Therapy Enhances Bidirectional Blood-Brain Barrier Permeability In Glioblastoma, Ryan T Cleary, Yiwei Fu, David Giles, Jinyun Yuan, Diogo P Moniz Garcia, Danny Palmer, Rowland H Han, Timothy Woodiwiss, Alicia B Yang, Dimitrios Mathios, Hong Chen, Albert H Kim
2020-Current year OA Pubs
BACKGROUND: Laser interstitial thermal therapy (LITT) is a minimally invasive treatment for glioblastoma that increases blood-brain barrier (BBB) permeability. However, the mechanisms and spatiotemporal features of this effect remain unclear. It is also unknown whether LITT promotes release of circulating tumor DNA (ctDNA).
METHODS: Using our previously developed LITT mouse model, we employed single-cell RNA-sequencing (scRNA-seq) to investigate gene expression changes in endothelial cells following LITT in the naive mouse brain. Brains were also harvested at multiple time points to assess LITT effects on tight junction (TJ) integrity and transcytosis via immunofluorescence and transmission electron microscopy. Human glioblastoma tissues were …
Waste Material Utilization In Civil Engineering Applications: Advances, Challenges, And Future Directions—A Scoping Review, Chathurika Dassanayake, Nuha S. Mashaan, Ridmi Galagedara
Waste Material Utilization In Civil Engineering Applications: Advances, Challenges, And Future Directions—A Scoping Review, Chathurika Dassanayake, Nuha S. Mashaan, Ridmi Galagedara
Research outputs 2022 to 2026
This PRISMA-guided scoping review examines the use of waste materials in civil engineering as a sustainable approach to reducing environmental impacts, conserving natural resources, and supporting circular economy principles. The rapid growth of urbanization, industrialization, mining, and agricultural activities generates large amounts of waste materials, including fly ash, ground granulated blast-furnace slag, bauxite residue, mining tailings, waste rock, acid-mine drainage sludge, waste plastics, post-consumer vulcanized rubber, recycled construction materials, and agricultural ashes. The disposal of these materials often creates serious environmental and land-use problems, making their reuse increasingly important. In this context, civil engineering is one of the most promising …
The Anatomy Of Earnings Conference Calls: An Integrative Framework For Management Research, Matthew P. Mount, Gokhan Ertug, Wei Shi, Tengjian Zou
The Anatomy Of Earnings Conference Calls: An Integrative Framework For Management Research, Matthew P. Mount, Gokhan Ertug, Wei Shi, Tengjian Zou
Research Collection Lee Kong Chian School Of Business
Over the last decade, there has been an explosion in the use of diverse data sources by management scholars to observe and capture managerial and organizational constructs that have historically been difficult to access. This surge has been driven by the growing availability of rich, multi-modal data—textual, image, and audio (Luo, Jia, Ouyang, & Fang, 2024)—together with advances in analytical techniques to process and analyze data, such as computer-aided text analysis (Harrison, Thurgood, Boivie, & Pfarrer, 2019), machine learning (Choudhury, Wang, Carlson, & Khanna, 2019; Harrison, Josefy, Kalm, & Krause, 2023), and deep learning (Gouvard, Goldberg, & Srivastava, 2023). These …
Securing A Calibrated Marketing Budget, Junqiu Jiang, Kapil R. Tuli, Nirmalya Kumar
Securing A Calibrated Marketing Budget, Junqiu Jiang, Kapil R. Tuli, Nirmalya Kumar
Research Collection Lee Kong Chian School Of Business
This study investigates the sociopolitical processes underlying the development and approval of marketing budgets in large multinational corporations. While prior research has focused extensively on optimizing the level and allocation of marketing budgets, little attention has been paid to the internal organizational dynamics that shape the marketing budgeting process. Drawing on the theories-in-use of both CMOs and CEOs, this study examines how these executives codevelop a calibrated marketing budget (CMKB)—a budget that aligns expected performance with allocated resources through an iterative, participative process. Field data show that CMOs deploy a set of signals to assuage CEO concerns related to goal …
Collecting Data Amid Resistance: Earning Faculty Trust While Revising Writing Program Assessment Practices, Carl Schlachte, Gregory Bruno
Collecting Data Amid Resistance: Earning Faculty Trust While Revising Writing Program Assessment Practices, Carl Schlachte, Gregory Bruno
Publications and Research
This article examines the process one community college first-year writing program used to revise its exit criteria for the first-semester composition course. The authors reflect on the complexities of revising program policies through shared decision-making practices without pausing the operation or offering of courses. This article, which we imagine will be useful for writing program administrators, department chairs, and committee members tasked with the work of revising writing program curricula or assessment practices, is particularly pointed toward those seeking to cultivate confidence with institutional research in their faculty and colleagues, and to view both data and change initiatives as tools …
Professional Dispositions In Coaching Education: Icf-Credentialed Coaches’ Perspectives On Development And Assessment, Michelle Renee Thompson
Professional Dispositions In Coaching Education: Icf-Credentialed Coaches’ Perspectives On Development And Assessment, Michelle Renee Thompson
Electronic Theses and Dissertations
This qualitative phenomenological study examined how professional dispositions were defined, experienced, and assessed in coaching education within the rapidly expanding field of professional coaching. The problem addressed was the lack of a clear understanding of professional dispositions in coaching and the absence of a systematic dispositional assessment comparable to that in counselor education. The researcher’s purpose was to explore how credentialed professional-level coaches defined and identified professional dispositions for effective coaching engagements and how these dispositions aligned with constructs in other helping professions. The researcher collected data through semistructured videoconference interviews. Purposeful and snowball sampling yielded 16 U.S.-based coaches who …
Multi-Parametric Nonlinear Programming For Lossy Lmp Sensitivity Analysis Using Outer Progressive Cuts, Yuhan Huang, Tao Ding, Chenggang Mu, Rui Bo, Pengwei Du
Multi-Parametric Nonlinear Programming For Lossy Lmp Sensitivity Analysis Using Outer Progressive Cuts, Yuhan Huang, Tao Ding, Chenggang Mu, Rui Bo, Pengwei Du
Electrical and Computer Engineering Faculty Research & Creative Works
Accurate sensitivity analysis of locational marginal price (LMP) is crucial for risk hedging and market management. This paper proposes multiparametric nonlinear programming for sensitivity analysis of LMP with nonlinear network loss, also known as lossy LMP. Global analytical solutions for lossy LMP and the corresponding critical regions are derived. An outer progressive cut algorithm is developed to constrain the network loss error within a specific range for the whole parametric domain. Case studies show the improved accuracy over methods with lossless or fixed loss factors, and a two-order-of-magnitude online speedup over Monte Carlo methods while maintaining lower total computational time.
A Nationwide Central Diagnosis For Pediatric Cns Tumors In Japan: The Jccg Brain Tumor And Pathology Committees, Yoshiko Nakano, Junko Hirato, Takako Yoshioka, Tetsuya Takimoto, Sumihito Nobusawa, Kaishi Satomi, Ran Tomomasa, Seiji Yamada, Taku Homma, Shoh Sasaki, Ayako Yamazaki, Maki Sakaguchi, Yasuhide Takeuchi, Nei Fukazawa, Kai Yamasaki, Kohei Fukuoka, Yui Shinohara Kimura, Yuki Nagayama, Yohei Inoue, Akira Miyahira, Ema Yoshioka, Asako Katsuma, Hayato Fukusumi, Tomoko Shofuda, Yuko Hibiya, Yuko Matsushita, Mai Honda Kitahara, Yuki Yomoda, Miho Kato, Michael D Taylor, Yasuhito Arai, Tatsuhiro Shibata, Hiroaki Sakamoto, Keita Terashima, Yoshiki Arakawa, Toshihiro Kumabe, Ryo Nishikawa, Junichi Hara, Yonehiro Kanemura, Koichi Ichimura
A Nationwide Central Diagnosis For Pediatric Cns Tumors In Japan: The Jccg Brain Tumor And Pathology Committees, Yoshiko Nakano, Junko Hirato, Takako Yoshioka, Tetsuya Takimoto, Sumihito Nobusawa, Kaishi Satomi, Ran Tomomasa, Seiji Yamada, Taku Homma, Shoh Sasaki, Ayako Yamazaki, Maki Sakaguchi, Yasuhide Takeuchi, Nei Fukazawa, Kai Yamasaki, Kohei Fukuoka, Yui Shinohara Kimura, Yuki Nagayama, Yohei Inoue, Akira Miyahira, Ema Yoshioka, Asako Katsuma, Hayato Fukusumi, Tomoko Shofuda, Yuko Hibiya, Yuko Matsushita, Mai Honda Kitahara, Yuki Yomoda, Miho Kato, Michael D Taylor, Yasuhito Arai, Tatsuhiro Shibata, Hiroaki Sakamoto, Keita Terashima, Yoshiki Arakawa, Toshihiro Kumabe, Ryo Nishikawa, Junichi Hara, Yonehiro Kanemura, Koichi Ichimura
Faculty, Staff and Students Publications
In 2016, the Japan Children's Cancer Group launched a nationwide research initiative to provide central diagnosis incorporating pathology review and molecular profiling for pediatric central nervous system (CNS) tumors. Over the first eight years, 2224 cases were registered. Non-next-generation sequencing analyzes, such as pyrosequencing and NanoString, were routinely performed, mainly for glioma, medulloblastoma, and ependymoma. Additional analyzes, including methylation profiling and RNA sequencing, were conducted for selected diagnostically challenging cases. The most common diagnoses were low-grade glioma (26%), medulloblastoma (18%), germ cell tumor (16%), high-grade glioma (12%), and ependymoma (11%). Diagnostic or targetable alterations were detected in nearly half of …
Challenge-Based Ex Vivo Immune Profiling Reveals Stimulus-Dependent Peripheral Immune Reprogramming In Alzheimer's Disease, C. A. Naranjo-Galvis, Jovanny Zabaleta, Ney Alliey Rodriguez, Luisa Matilde Salamanca-Duque
Challenge-Based Ex Vivo Immune Profiling Reveals Stimulus-Dependent Peripheral Immune Reprogramming In Alzheimer's Disease, C. A. Naranjo-Galvis, Jovanny Zabaleta, Ney Alliey Rodriguez, Luisa Matilde Salamanca-Duque
School of Medicine Publications
Altered immune function is increasingly recognized as a contributor to Alzheimer's disease (AD); however, it remains unclear whether peripheral immune alterations reflect constitutive inflammation or stimulus-dependent changes in immune responsiveness. Addressing this distinction is critical for understanding immune dysregulation in neurodegenerative diseases. In this study, we applied a challenge-based ex vivo immune profiling approach to characterize functional immune responsiveness in patients with AD and in cognitively healthy older adults. Peripheral blood mononuclear cells were exposed to defined innate, antigenic, and mitogenic stimuli, and cytokine and β-amyloid (Aβ) responses were quantified in culture supernatants. Diagnosis-by-stimulus interaction effects were assessed using generalized …
Evidence-Based Classification Of Genes Implicated In Skeletal Disorders Using The Clingen Curation Framework, Ryan F Webb, Hannah Mccurry, Amanda Girod, Madeline Hughes, Emma Wilcox, Mayher Patel, Eleanor C Broeren, Kezang C Tshering, Marina Distefano, Lorenzo D Botto, Lindsay C Burrage, Valérie Cormier-Daire, Juan Dong, Nadja Ehmke, Deborah Krakow, Shahida Moosa, Geert Mortier, Sandesh Nagamani, Loren Pena, Pedro A Sanchez-Lara, Andrea Superti-Furga, Sheila Unger, Danita Velasco, Matthew L Warman, Kerry Brown, Deepika D'Cunha Burkardt, Carlos R Ferreira
Evidence-Based Classification Of Genes Implicated In Skeletal Disorders Using The Clingen Curation Framework, Ryan F Webb, Hannah Mccurry, Amanda Girod, Madeline Hughes, Emma Wilcox, Mayher Patel, Eleanor C Broeren, Kezang C Tshering, Marina Distefano, Lorenzo D Botto, Lindsay C Burrage, Valérie Cormier-Daire, Juan Dong, Nadja Ehmke, Deborah Krakow, Shahida Moosa, Geert Mortier, Sandesh Nagamani, Loren Pena, Pedro A Sanchez-Lara, Andrea Superti-Furga, Sheila Unger, Danita Velasco, Matthew L Warman, Kerry Brown, Deepika D'Cunha Burkardt, Carlos R Ferreira
Faculty, Staff and Students Publications
More than 770 genetic skeletal disorders have been described, most with disease-causing variants reported in 1 of over 550 different genes. The ClinGen Skeletal Disorders Gene Curation Expert Panel was established to determine the strength of the evidence that supports specific gene-disease relationships (GDRs). Such information can assist clinical testing laboratories in choosing genes that should be included on diagnostic panels. Nine genes accounting for the most frequently encountered skeletal dysplasias (COL1A1, COL1A2, COL2A1, FGFR3, SLC26A2, TRPV4, COMP, ALPL, and SOX9) associated in the medical literature with 26 different skeletal disorders were reviewed using a semi-quantitative scoring framework. This framework …
High-Throughput Quantitation Of Pathogen-Induced Calcium Signals Captured Through Live-Cell Fluorescence Microscopy, J Thomas Gebert, Ethan M Huleatt, Francesca J Scribano, Michael R Eledge, Lauren E Dorn, Sammy K Hasmi, Joseph M Hyser
High-Throughput Quantitation Of Pathogen-Induced Calcium Signals Captured Through Live-Cell Fluorescence Microscopy, J Thomas Gebert, Ethan M Huleatt, Francesca J Scribano, Michael R Eledge, Lauren E Dorn, Sammy K Hasmi, Joseph M Hyser
Faculty, Staff and Students Publications
Many intracellular pathogens manipulate host cell calcium to facilitate their survival and replication. Live-cell microscopy using fluorescent calcium indicators has become an indispensable tool for characterizing the mechanisms underlying both homeostatic and pathogen-induced cellular calcium dynamics, but such imaging must be coupled with robust quantitative analysis. Further, calcium imaging is most powerful when paired with reductive studies targeting calcium-modulating proteins. The lack of specific inhibitors or agonists to directly target most pathogen-induced calcium signals precludes many of the approaches that have allowed for robust characterization of major eukaryotic cell calcium signaling mechanisms, such as ER Ca2+ release by inositol triphosphate …
Performance Of Fecal Calprotectin And Serum Procalcitonin For The Diagnosis Of Spontaneous Bacterial Peritonitis In Patients With Cirrhosis: A Prospective Diagnostic Accuracy Study, Mandip Singh Bhatia, Devarakonda Uday Teja, Nipun Verma, Archana Angrup, Saurabh Chandrabhan Sharda
Performance Of Fecal Calprotectin And Serum Procalcitonin For The Diagnosis Of Spontaneous Bacterial Peritonitis In Patients With Cirrhosis: A Prospective Diagnostic Accuracy Study, Mandip Singh Bhatia, Devarakonda Uday Teja, Nipun Verma, Archana Angrup, Saurabh Chandrabhan Sharda
Faculty, Staff and Students Publications
Background:: Spontaneous bacterial peritonitis (SBP) is a life-threatening complication in patients with cirrhosis and ascites. This study aimed to evaluate the diagnostic performance of biomarkers—calprotectin (serum, ascitic, fecal) and serum procalcitonin (PCT)—for SBP.
Methods:: This prospective diagnostic accuracy study, enrolled 137 consecutive patients with cirrhosis and ascites at a tertiary care center in India. Participants were categorized into SBP (n = 55) and non-SBP (n = 82) groups based on the reference standard of ascitic fluid neutrophil count. Serum, ascitic fluid, and fecal calprotectin were measured by enzyme-linked immunosorbent assay, and serum PCT was measured by electrochemiluminescence immunoassay. …
Cytokine-Based Strategies To Improve Prognostic Enrichment Of Pediatric Ards, E Scott Halstead, Todd M Umstead, Zissis C Chroneos, Cainan Riccio-Baum, S Rameeza Allie, Daniel J Mckeone, Debbie Spear, Ryan A Nofziger, Ronald C Sanders, Danielle Ahn, Jasmine C Dowell, Asdis F Wagner, Neal J Thomas, Prithvi Sendi, W Joshua Frazier, Courtney M Rowan, Parag N Jain, Dalia A Bashir, Stuart H Friess, Brian M Varisco, Jocelyn Grunwell, Aline B Maddux, Stephen T Famularo, Nadir Yehya
Cytokine-Based Strategies To Improve Prognostic Enrichment Of Pediatric Ards, E Scott Halstead, Todd M Umstead, Zissis C Chroneos, Cainan Riccio-Baum, S Rameeza Allie, Daniel J Mckeone, Debbie Spear, Ryan A Nofziger, Ronald C Sanders, Danielle Ahn, Jasmine C Dowell, Asdis F Wagner, Neal J Thomas, Prithvi Sendi, W Joshua Frazier, Courtney M Rowan, Parag N Jain, Dalia A Bashir, Stuart H Friess, Brian M Varisco, Jocelyn Grunwell, Aline B Maddux, Stephen T Famularo, Nadir Yehya
Faculty, Staff and Students Publications
Background: Hyper-inflammation is common to multiple critical care syndromes, including acute respiratory distress syndrome (ARDS) and sepsis, and is associated with worse outcomes. A signature of hyper-inflammatory ARDS has been described in adults using IL-6, TNFR1, and bicarbonate, and has prognostic utility. We investigated the application of this traditional parsimonious signature to pediatric ARDS patients and tested whether we could improve prognostic enrichment using other cytokines.
Methods: We leveraged a prospective multicenter cohort study of 500 children with ARDS (Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome [LEOPARDS]; NCT04113434) study. Plasma samples were obtained within 24 h …
Irrigation Use In A Changing Landscape: A Combined Economic And Hydrologic Approach, Noormah Rizwan, Jamshid Jahali, Molly Sears, Sean Woznicki, Tao Liu, Oskar Marko, Mirjana Radulović
Irrigation Use In A Changing Landscape: A Combined Economic And Hydrologic Approach, Noormah Rizwan, Jamshid Jahali, Molly Sears, Sean Woznicki, Tao Liu, Oskar Marko, Mirjana Radulović
Michigan Tech Publications
Warmer temperatures and erratic rainfall patterns are threatening global water availability. Irrigation is a key risk-mitigation strategy, helping sustain crop yields under climate stress. Limited research has examined farmers' likelihood of irrigating under climate change, or the effects of large-scale irrigation expansion on future water availability, largely due to challenges in acquiring field-level irrigation data. Using an integrated econometric-hydrologic modeling approach, we investigate how short- and long-run climatic conditions shape irrigation incentives and feasibility in Serbia—an increasingly water-stressed region—and how these incentives evolve under future climate scenarios. Our econometric model identifies when and where irrigation becomes a viable option under …
Advancing Dimensional Models Of Psychopathology In Cancer: Insights From Applying The Hierarchical Taxonomy Of Psychopathology (Hitop), Darren Haywood, Jai Carmichael, Miriam K. Forbes, Roman Kotov, Robert F. Krueger, Aidan G.C. Wright, Susan L. Rossell, David Castle, Wendy Lam, Maryam Lustberg, Colin E. Vize, Anna Ugalde, Phyllis Butow, Nicolas H. Hart
Advancing Dimensional Models Of Psychopathology In Cancer: Insights From Applying The Hierarchical Taxonomy Of Psychopathology (Hitop), Darren Haywood, Jai Carmichael, Miriam K. Forbes, Roman Kotov, Robert F. Krueger, Aidan G.C. Wright, Susan L. Rossell, David Castle, Wendy Lam, Maryam Lustberg, Colin E. Vize, Anna Ugalde, Phyllis Butow, Nicolas H. Hart
Research outputs 2022 to 2026
Objective: Cancer survivors, defined as those living with or beyond a cancer diagnosis, experience more than double the prevalence of psychopathology when compared to the general population. Categorical diagnostic systems, such as the Diagnostic and Statistical Manual of Mental Disorders (DSM), remain dominant in psycho-oncology despite concerns about reliability, validity, and clinical utility for this population. Dimensional frameworks, such as the Hierarchical Taxonomy of Psychopathology (HiTOP), offer a more precise alternative; however, they have not yet been widely applied in cancer survivors. Accordingly, the objective of this research was to examine the applicability of HiTOP to cancer survivors. Methods: Data …
From Hermeneutic Theory To Pedagogical Practice: Dialogue, Fusion Of Horizons, And Tradition In The Philosophy For Children Classroom, Leon Benade
Research outputs 2022 to 2026
This article brings Hans-Georg Gadamer’s philosophical hermeneutics into critical conversation with the pedagogical practice of philosophy in schools, focusing particularly on Philosophy for Children (P4C). While P4C offers a rich pedagogical model for developing reasonableness through the Community of Inquiry (CoI), its account of the conditions under which understanding occurs remains somewhat underdeveloped. Although some scholars have situated P4C in relation to hermeneutics, this engagement is limited. Addressing this gap, the key Gadamerian ideas of tradition, prejudice, and the fusion of horizons and dialogue are explored here to deepen and extend the theoretical considerations of inquiry in P4C. The discussion …
Inpatient Versus Outpatient Management Of Bilateral Optic Nerve Head Elevation Presentation To A Tertiary Emergency Department, Mengchen Suo, Johnny Lo, Fred K. Chen
Inpatient Versus Outpatient Management Of Bilateral Optic Nerve Head Elevation Presentation To A Tertiary Emergency Department, Mengchen Suo, Johnny Lo, Fred K. Chen
Research outputs 2022 to 2026
Introduction: Increased accessibility to fundus cameras has changed the referral pattern for patients with suspected bilateral optic nerve head elevation (BONHE) presenting to emergency departments (EDs). We aim to review the management of these patients to streamline the process. Methods: A retrospective review of patients with suspected BONHE referred to a tertiary centre ED between 2017 and 2022. We collected demographics, referral source, clinical assessment, neuroimaging and retinal imaging results. Final diagnosis and treatment outcomes were compared between those managed as inpatients and those managed as outpatients. Results: 100 patients were referred to the ED with a suspected BONHE. Most …
Dasyurus Hallucatus Movement Response To Fire In A Complex, Resource Rich Tropical Savanna, Ian J. Radford, Annette Cook, Natasha Harrison, Ben Corey, Roberta Bencini, Harriet R. Mills
Dasyurus Hallucatus Movement Response To Fire In A Complex, Resource Rich Tropical Savanna, Ian J. Radford, Annette Cook, Natasha Harrison, Ben Corey, Roberta Bencini, Harriet R. Mills
Research outputs 2022 to 2026
The northern quoll, Dasyurus hallucatus, is part of a suite of threatened native northern Australian mammals that have inappropriate fire regimes listed as a threatening process. However, fire responses reported for D. hallucatus are inconsistent among different studies. Based on the theory that the fire response of D. hallucatus will depend partially on habitat quality, we postulate that home range in high quality savannas of the north Kimberley will be small, post-breeding male mortality low and prey resources little affected by fire. Based on previous research we hypothesised that male D. hallucatus would respond to fire more than females. By …
Muscle–Tumor Crosstalk In Exercise Oncology: Exercise-Induced Myokines And Cancer Cachexia, Amirhossein Ahmadi Hekmatikar, Francesco Bettariga, Álvaro López Llorente, Diego Fernández-Lázaro, Katsuhiko Suzuki, D. Maryama Awang Daud
Muscle–Tumor Crosstalk In Exercise Oncology: Exercise-Induced Myokines And Cancer Cachexia, Amirhossein Ahmadi Hekmatikar, Francesco Bettariga, Álvaro López Llorente, Diego Fernández-Lázaro, Katsuhiko Suzuki, D. Maryama Awang Daud
Research outputs 2022 to 2026
Exercise-induced myokines, such as IL-6, irisin, and myostatin, play crucial roles in mediating systemic adaptations and modulating tumor progression. This narrative review synthesizes evidence on how regular moderate-intensity exercise affects the myokine network within the tumor microenvironment (TME) of solid tumors. Results from the 86 included studies indicate that structured training (aerobic: 45–65% VO2 max; resistance: 45–70% 1RM) enhances the expression of beneficial myokines that support immune surveillance, reduce inflammation, and improve muscle–tumor cross-talk. IL-6 demonstrates a dual modulatory effect on inflammation and immunity; irisin contributes to tumor apoptosis, while myostatin downregulation supports muscle integrity and metabolic balance. Evidence suggests …
Development And Evaluation Of An Automated Report-Based Chart Checking Tool In External Beam Radiotherapy, Andrew Wroe
Development And Evaluation Of An Automated Report-Based Chart Checking Tool In External Beam Radiotherapy, Andrew Wroe
All Publications
Background: Computerized radiotherapy chart checking tools have revolutionized the initial physics chart review process as they offer verification of large amounts of plan parameters in seconds and allow physicists to concentrate on high-skill-level items that are challenging for automation. Both commercialized and in-house chart check solutions typically rely on access to the patient data within the live SQL database of the radiation oncology information system (ROS). This is a complex task potentially posing risks to both database integrity and overall system performance when accessed during clinic operation hours.
Purpose: The aim of this study was to develop and test a …
Supported Decision-Making And The Inclusion Of People Who Lack Decisional Capacity In Greater Than Minimal Risk Research, Aaron Eli Segal, David Wendler, Dana Howard
Supported Decision-Making And The Inclusion Of People Who Lack Decisional Capacity In Greater Than Minimal Risk Research, Aaron Eli Segal, David Wendler, Dana Howard
Faculty and Staff Publications
In recent years, some have argued that supported decision-making can be ethically superior to surrogate decision-making with respect to decisions involving adults with cognitive and intellectual impairments or disabilities. In this paper, we argue that supported decision-making could also be ethically superior to surrogate decision-making in the context of clinical research that involves greater than minimal net risks. In current practice, adults who lack decisional capacity are often excluded from research that involves greater than minimal net risks (call this the minimal risk requirement). While this approach is intended to protect them, it can be ethically problematic, in part because …
Autonomous Stress Testing In A Network Digital Twin For Predictive Remediation, Mohit Chandra, Amrita Mukherjee
Autonomous Stress Testing In A Network Digital Twin For Predictive Remediation, Mohit Chandra, Amrita Mukherjee
Defensive Publications Series
The management of complex telecommunications networks can be challenged by difficulties in predicting the impact of component failures and the risks of testing automations on a live system. Systems and methods are described that can address these challenges by creating and maintaining a graph-based digital representation, such as a digital twin, of an operational network that can be synchronized with real-time data. Within this digital twin, for example, an autonomous agent can perform synthetic fault injections to simulate a wide range of potential failures and stressors. The system can analyze the effects of these simulated faults to predict potential service-level …
The Impact Of Fear Of Aging On Luxury Consumption Among Middle-Aged Women, Jiyeon Lee, Xiaofei Wu, Dongwoo Ko
The Impact Of Fear Of Aging On Luxury Consumption Among Middle-Aged Women, Jiyeon Lee, Xiaofei Wu, Dongwoo Ko
Asia Marketing Journal
This study investigates the relationship between fear of aging and luxury consumption behaviors among middle-aged women, focusing on the psychological and social dimensions of aging anxiety. Utilizing frameworks such as Objectification Theory and the Double Standard of Aging, the research explores how aging anxiety impacts attitudes toward luxury goods, mediated by fear of negative evaluation and body esteem. A survey of 288 women aged 41 to 60 was conducted, revealing that fear of aging significantly influences luxury attitudes and purchasing intentions. Findings indicate that luxury goods are seen not only as tools for status maintenance but also as avenues for …
Sustained Reading: Multilingual Learners Exploring The Language Of A Text, Priscila J.B.M. Costa, Luciana C. De Oliveira, Meghan Love
Sustained Reading: Multilingual Learners Exploring The Language Of A Text, Priscila J.B.M. Costa, Luciana C. De Oliveira, Meghan Love
Journal of English Learner Education
In US schools, multilingual learners (MLs) are expected to meet the same rigorous disciplinary standards as their English-speaking peers while also developing proficiency in English. This article demonstrates how sustained reading, as part of the Teaching and Learning Cycle, can support MLs' access to disciplinary literacy through the explicit attention to language features. Grounded on the Language-based Approach to Content Instruction (LACI), the article presents a classroom vignette from a 5th-grade social studies lesson in which MLs dissected a mentor text. The lesson illustrates how code-breaking within sustained reading makes disciplinary language visible, helping students notice the linguistic choices common …
Snap Challenge In Teacher Education, Eric Hogan, Sean Forbes, Carey E. Andrzejewski
Snap Challenge In Teacher Education, Eric Hogan, Sean Forbes, Carey E. Andrzejewski
Journal on Empowering Teaching Excellence
Access the online Pressbooks version of this article here.
Training pre-service teachers often focuses on educating them about issues they will see in their own classrooms. One such issue is food insecurity. Food insecurity is defined by limited or uncertain access to nutritionally adequate and safe foods or the ability to acquire acceptable foods in socially acceptable ways (Rabbitt et al., 2023a). This article focuses on pre-service teachers' experiences while engaging in the SNAP Challenge to learn more about food insecurity while also learning how food impacts student learning and motivation. Participants in the study discussed how living off the …
Navigating Your First Technical Paper In Social Sciences: Understanding Single Case Research Design, Diana Parry-Cruwys, Allen Karsina, Jacquelyn M. Macdonald
Navigating Your First Technical Paper In Social Sciences: Understanding Single Case Research Design, Diana Parry-Cruwys, Allen Karsina, Jacquelyn M. Macdonald
Journal on Empowering Teaching Excellence
Access the online Pressbooks version of this article here.
Reading and understanding a research article utilizing single case research design (SCRD) may be a particularly challenging hurdle students face when starting graduate level coursework in the social and health sciences. This paper helps ease this challenge by describing what SCRD is and why it is important to understand when interpreting results in SCRD papers. Additionally, it will explain the various parts of a single case research design paper and what should be included in each section. To understand the results of SCRD, it is imperative that students understand experimental design. …
Poetry As Performance: The Case For "Camp" In Catullus, Jasmine Patera
Poetry As Performance: The Case For "Camp" In Catullus, Jasmine Patera
Floodwall Magazine
No abstract provided.