Digital Commons Network^™

Hierarchical Search Method For Gravitational Waves From Stellar-Mass Binary Black Holes In Noisy Space-Based Detector Data, Yao Fu, Yan Wang, Soumya D. Mohanty

Physics & Astronomy Faculty Publications

Future space-based laser interferometric detectors, such as the Laser Interferometer Space Antenna (LISA), will be able to detect gravitational waves (GWs) generated during the inspiral phase of stellar-mass binary black holes (SmBBHs). These detections contain a wealth of important information concerning astrophysical formation channels and fundamental physics constraints. However, the detection and characterization of GWs from SmBBHs poses a formidable data analysis challenge, arising from the large number of wave cycles that make the search extremely sensitive to mismatches in signal and template parameters in a likelihood-based approach. This makes the search for the maximum of the likelihood function over …

Identification And Functional Characterization Of The Icse1 Gene From Ilex Cornuta, Xiaoxi Zhang, Li Zhu, Weiwei Zhang, Feng Xu, Jiabao Ye, Yongling Liao

Turkish Journal of Agriculture and Forestry

Ilex cornuta (I. cornuta) is a traditional Chinese medicine that is rich in various secondary metabolites with pharmacological activities, among which triterpenoid saponins are one of the main active components. Squalene epoxidase (SE) is a key regulatory enzyme in the biosynthesis of triterpenoids. In this study, we isolated a squalene epoxidase (IcSE1) from I. cornuta and analyzed its molecular characteristics and functions. The results indicated that the total length of the IcSE1 sequence was 1942 bp, which includes a 1638 bp open reading frame (ORF) that encodes 545 amino acids. The theoretical isoelectric point (pI) and molecular weight of the …

Is Universal Health Coverage Really Better? Unintended Consequences Of The 2019 Amendment Of The National Health Insurance Act For Humanitarian Sojourners In South Korea, Minji Ju, Minah Kang, Eunice Y. Park

Department of Public Health Scholarship and Creative Works

Background

South Korea achieved universal health coverage (UHC) through the National Health Insurance (NHI). However, humanitarian sojourners under temporary stay permits were initially excluded. Alongside recommendations from the National Human Rights Commission of Korea (NHRCK), the 2019 Amendment of the NHI Act expanded eligibility of the NHI. While this marked significant progress toward greater universality in health care, it also led to unintended consequences for humanitarian sojourners.

Methods

This study employed a two-fold approach aligned with the trajectory of the Amendment. First, we conducted semi-structured in-depth interviews to analyze diverse perspectives on the universality of health coverage, the benefits of …

Peter Sauers V. Oak Property Management Lp

2025 Decisions

USDC for the Eastern District of Pennsylvania

Usa V. Daniel Teed

2025 Decisions

USDC for the Western District of Pennsylvania

Robert Archie V. Hamilton Township Municipal Court

2025 Decisions

USDC for the District of New Jersey

Robert Swift V. Bhuwan Pandey

2025 Decisions

USDC for the District of New Jersey

Steering Minutes 02/11/2025, Steering Committee

Steering Committee

No abstract provided.

3d Printed Physically Unclonable Wireless Systems (Puws), Gokhan Mumcu, Huseyin Arslan

USF Patents

Three-dimensional (3D) printing is implemented to introduce randomness into systems and devices that are being manufactured. 3D printed physically unclonable wireless systems (PUWS) provide flexibility in system package complexity, number of physically unclonable function (PUF) based security measures/types, and customization of the PUF parameters. Using flexibility and economics of 3D printing, PUWS can combine multiple PUF measures in a 3D package for cryptographic secret keys and introduce PUFs at the physical layer of the communication system. A 3D printed wireless system packaging concept is described herein where 3D printing parameters are randomized to 1) generate new physically unclonable functions (at …

Molecular Screening Of Septoria-Resistant Genes In Historical Turkish Bread Wheat Germplasm Using The Validated Gene Specific Ssr Markers, Amjad Ali, Fati̇h Ölmez, Muhammed Tatar, Parnaz Mortazavi, Muhammad Tanveer Altaf, Emi̇ne Burcu Turgay, Hüsnü Aktaş, Muhammad Azhar Nadeem, Jazib Javed, Jin-Ying Gou, Muhammad Aasim, Abdelfattah A. Dababat, Faheem Shehzad Baloch

Turkish Journal of Agriculture and Forestry

Septoria tritici blotch (STB), caused by Zymoseptoria tritici, poses a significant threat to global wheat production, particularly in Türkiye. Resistance breeding is the most sustainable and effective disease control method. Molecular markers, especially simple sequence repeat (SSR) markers are extensively employed in wheat breeding to enhance the efficacy. The primary objective of this study was to identify Stb resistance genes among 143 historical registered Turkish bread wheat genotypes released as commercial cultivars between 1963 to 2014, using 16 closely linked SSR markers. The findings revealed substantial genetic variation among the screened cultivars, with the Stb3 gene being the most prevalent, …

Otolaryngology Practitioner Attitudes Toward Human Papillomavirus Vaccination In Academic Otolaryngology Clinics, Dante J. Merlino, Katelyn S. Rourk, George B. Sankar, Adam J. Luginbuhl, Brian J. Boyce, Michelle M. Chen, Eric M. Dowling, Michael C. Topf, Raymond L. Chai, Karthik Rajasekaran, Eric J. Moore, Daniel L. Price, George Saieed, Kathryn M. Van Abel

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Despite the existence of a highly effective and safe vaccine against human papillomavirus (HPV) infection, vaccination rates remain low. The most prevalent HPV-associated malignancy in the United States is oropharyngeal cancer, but otolaryngology practitioners do not offer the HPV vaccine, and their feelings around offering HPV vaccination have not been evaluated. A 43-question survey, including a twelve-question knowledge quiz, was sent to otolaryngology practitioners at seven academic institutions. Twelve questions comprised a knowledge quiz testing practitioner understanding of HPV, while the remainder of the questions evaluated comfort with and likelihood of recommending vaccination. Of the 442 practitioners who were sent …

Thrombocytopenia In Sepsis, Alireza Setarehaseman, Robert W. Maitta

Faculty Scholarship

Platelets, traditionally known for their role in hemostasis, have emerged as key players in immune response and inflammation. Sepsis, a life-threatening condition characterized by systemic inflammation, often presents with thrombocytopenia, which at times, can be significant. Platelets contribute to the inflammatory response by interacting with leukocytes, endothelial cells, and the innate immune system. However, excessive platelet activation and consumption can lead to thrombocytopenia and exacerbate the severity of sepsis. Understanding the multifaceted roles of platelets in sepsis is crucial for developing effective therapeutic strategies. Targeting platelet-mediated inflammatory responses and promoting platelet production may offer potential avenues for improving outcomes in …

The Economics Of Large Language Models: Token Allocation, Fine-Tuning, And Optimal Pricing, Dirk Bergemann, Alessandro Bonatti, Alex Smolin

Cowles Foundation Discussion Papers

We develop an economic framework to analyze the optimal pricing and product design of Large Language Models (LLM). Our framework captures several key features of LLMs: variable operational costs of processing input and output tokens; the ability to customize models through fine-tuning; and high-dimensional user heterogeneity in terms of task requirements and error sensitivity. In our model, a monopolistic seller offers multiple versions of LLMs through a menu of products. The optimal pricing structure depends on whether token allocation across tasks is contractible and whether users face scale constraints. Users with similar aggregate value-scale characteristics choose similar levels of fine-tuning …

Mbnl Overexpression Rescues Cardiac Phenotypes In A Myotonic Dystrophy Type 1 Heart Mouse Model, Rong-Chi Hu, Yi Zhang, Larissa Nitschke, Sara J Johnson, Ayrea E Hurley, William R Lagor, Zheng Xia, Thomas A Cooper

Faculty, Staff and Students Publications

Myotonic dystrophy type 1 (DM1) is an autosomal dominant disease caused by a CTG repeat expansion in the dystrophia myotonica protein kinase (DMPK) gene. The expanded CUG repeat RNA (CUGexp RNA) transcribed from the mutant allele sequesters the muscleblind-like (MBNL) family of RNA-binding proteins, causing their loss of function and disrupting regulated pre-mRNA processing. We used a DM1 heart mouse model that inducibly expresses CUGexp RNA to test the contribution of MBNL loss to DM1 cardiac abnormalities and explored MBNL restoration as a potential therapy. AAV9-mediated overexpression of MBNL1 and/or MBNL2 significantly rescued DM1 cardiac phenotypes including conduction delays, contractile …

Scientific Evidence: Impact On A Jury, Thomas B. Scavone

Walden Dissertations and Doctoral Studies

The goal of this qualitative study was to better understand the impact of scientific evidence ‘s influence on a jury’s verdict. The presence of scientific evidence has the potential to convict the defendant or overturn a guilty verdict as seen in cases involving the innocence project. The theoretical framework for this qualitative study was Gerbner’s Cultivation Theory which postulates heavy exposure to television has the potential to influence the individual’s perception of the world. The researcher implemented an exploratory research design using purposive sampling. A total of 68 participants (prior jurors) applied for the study, 66 from an advertisement placed …

Engineered Immunomodulatory Extracellular Vesicles From Epithelial Cells With The Capacity For Stimulation Of Innate And Adaptive Immunity In Cancer And Autoimmunity, Xin Luo, Fernanda G Kugeratski, Dara P Dowlatshahi, Hikaru Sugimoto, Kent A Arian, Yibo Fan, Li Huang, Danielle Wills, Sergio Lilla, Kelly Hodge, Sara R Zanivan, Valerie S Lebleu, Kathleen M Mcandrews, Raghu Kalluri

Faculty, Staff and Student Publications

Extracellular vesicles (EVs) are generated by all cells. Systemic administration of allogenic EVs derived from epithelial and mesenchymal cells have been shown to be safe, despite carrying an array of functional molecules, including thousands of proteins. To address whether epithelial cells derived EVs can be modified to acquire the capacity to induce immune response, we engineered 293T EVs to harbor the immunomodulatory molecules CD80, OX40L and PD-L1. We demonstrated abundant levels of these proteins on the engineered cells and EVs. Functionally, the engineered EVs efficiently elicited positive and negative co-stimulation of human and murine T cells. In the setting of …

Use Of Synthetic Water-Soluble Kcc2 To Modulate Chloride Homeostasis In Cultured Dopamine-Neuron-Like Cells, Mason Terry, Andrew Payne, Dario Mizrachi

Annual Research Symposium

No abstract provided.

Staff Attitude, Library Policies And Service Delivery In University Libraries In Ogun State, Nigeria, Ilori Edeole Maria Mrs, Owolabi Ruth O Dr, Oden Abigail N. Mrs, Ogungbade Aderonke A. Mrs

Library Philosophy and Practice (e-journal)

University library services aim to meet the information needs of the university community, fostering learning and research. Quality service, particularly in tangible aspects and reliability, leads to user satisfaction. Staff attitude significantly impacts library service utilization, as does library policy, which guides library operations. The study adopted survey research design. The study population comprised 80,247 university library users in Ogun State, Nigeria. A sample size of 1,513 was determined using the Krejcie and Morgan (1970) method. Universities were stratified into federal, state, and private categories, and respondents were purposively selected. The findings indicate high-quality service delivery in university libraries in …

Complete Issue - Mend (Spring 2025), Mend Journal

Mend

No abstract provided.

Juneteeth, Sonny Cochran

Mend

No abstract provided.

Characterization Of 1,8-Cineole (Eucalyptol) From Myrtle And Its Potential Antibacterial And Antioxidant Activities*, Humera Khan

Karbala International Journal of Modern Science

1,8-Cineole is a naturally occurring chemical molecule predominantly found in fragrant plants, particularly Myrtle. Its aroma is distinctive and has been the subject of numerous investigations due to its various biological actions. This study examines the characterization of 1,8-Cineole derived from Myrtle and investigates its antibacterial and antioxidant properties. This study seeks to compare 1,8-Cineole with antibiotics like Amoxicillin and Tetracycline, and moreover, to investigate its antioxidant capabilities against diverse bacterial strains (both Gram-positive and Gram-negative). 1,8-Cineole exhibits the most effective antibacterial properties, demonstrating an inhibition zone of 12.00 mm against Staphylococcus aureus and 10.00 mm against Pseudomonas aeruginosa. …

Shifting The Paradigm With Wednesday Addams: An Intersectional Analysis Of The First (Autistic) Female Latinx Detective, Camille Bassett, Jason Gilmore

Communication Studies and Philosophy Student Research

For centuries, Autistic people have been portrayed in media through two dehumanizing stereotypes, the robot and the superhuman savant. Together, the robot and the superhuman savant combine into one of the most popular hybrid stereotypes to appear in media: the detective. Past detectives have been almost exclusively white male characters, a longstanding pattern that erases Autistic women and people of color, among others. In 2022, however, Netflix’s spinoff series of The Addams Family, Wednesday, brought to the screen the first-ever female Latinx detective. This study is a thematic analysis of Wednesday as a character, the autism …

Curricular Changes Proposed For 2025-2027 Morris Catalog, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

The Joy Of Embodied Learning, Leslie Bayers

Academic Affairs Faculty and Staff Books and Book Chapters

The science of embodied cognition has established that thinking involves dynamic exchanges between the body and the brain and webs of interaction between humans and their environments. While learning draws on these connected ecosystems, persistent notions of the brain as separate from and hierarchically managing the body—an enduring legacy of Cartesian dualism—perpetuate static teaching and learning mindsets. Disregard for the body’s role in learning fuels disengagement, isolation, and inequity. This chapter weaves key findings from embodied learning research together with scenes from the author’s own academic journey to illustrate how leveraging brain–body connections can foster educational well-being. The author shares …

A Comparison Study Of Senior And Junior Deck Officers’ Interpretations Of The International Regulations For The Prevention Of Collisions At Sea, Ian Heffernan, Tom O'Mahony

Articles

The International Regulations for the Prevention of Collisions at Sea (IRPCS) provide a comprehensive set of instructions for watchkeeping officers to follow and prevent collisions at sea. This study compares how six newly qualified deck officers and six Master Mariners, who were all trained at the same college, applied the IRPCS. Individual, semi-structured interviews were used to uncover how the 12 participants applied and interpreted the rules for three authentic scenarios. Phenomenography was used to capture the qualitatively different means by which participants interpreted the IRPCS. For basic collision avoidance situations, the results indicated little difference between the cohorts' ability …

Casar Public Lecture: Will Trump End The Ukraine War?, The Prince Alwaleed Center For American Studies And Research Casar

Performances, Events, and Presentations

Trump wants to become the world’s Peace Maker, the Master of the Art of Making Deals. He promised to end this war in 24 hours. Yet the real question is whether Putin wants to end the war, or whether he is ready for a deal ? If so, then what kind of a deal? Could it be that Putin might have a different deal in mind than the deal Trump is willing to offer?? So what happens then??? The lecture deliberated about the possible answers to this very question from several perspectives, analyzing the impact on Egypt, the region & …

Million-Dollar Mysteries: Recent Complex Patent Cases Lost To Rule 36, Dennis D. Crouch

Faculty Publications

This article examines the Federal Circuit's continued use of Rule 36 summary affirmances to dispose of complex patent cases without written opinions. Through analysis of eight recent Rule 36 cases decided in early 2025, the author demonstrates that sophisticated legal issues involving millions of dollars are being summarily affirmed despite presenting novel and important questions of patent law. The cases discussed involve design patent evidentiary standards, jury trial rights for hybrid legal-equitable claims, analogous art determinations, claim construction, written description requirements, and PTAB procedural issues. The author argues that while the court may be avoiding difficult cases with complex factual …

In Re: Anthony Garvin

2025 Decisions

USDC for the Middle District of Pennsylvania

Tedor Davido V. Secretary Pennsylvania Department Of Corrections

2025 Decisions

USDC for the Eastern District of Pennsylvania

The International Law Commission's Seventy-Fifth (2024) Session: Immunity Of State Officials From Foreign Criminal Jurisdiction And Other Topics, Charles C. Jalloh

Articles

The International Law Commission (Commission or ILC) held its seventy-fifth session at its seat in Geneva from April 15 to May 31 and from July 1 to August 2, 2024. The Commission was chaired by Mr. Marcelo Vázquez-Bermúdez (Ecuador), and for the first time since its establishment in 1945, elected a majority of three females out of the five officers elected to its bureau annually. The Commission celebrated its seventy-fifth anniversary and progressed its work on the topics in the program of work despite the shortening of the twelve-week General Assembly approved session to ten weeks due to the liquidity …