Digital Commons Network^™

Loss Of Mucin 2 And Mhc Ii Molecules Causes Rare Resistance To Murine Rv Infection, Carolyn Bomidi, Faith M Sawyer, Noah Shroyer, Margaret Conner, Mary K Estes, Sarah E Blutt

Faculty, Staff and Students Publications

Enteric pathogen rotavirus (RV) primarily infects mature enterocytes at the tips of the intestinal villi; however, the role of secretory Paneth and goblet cells in RV pathogenesis remains unappreciated. Atoh1 knockout mice (Atoh1cKO) were used to conditionally delete Paneth, goblet, and enteroendocrine cells in the epithelium to investigate the role of secretory cells in RV infection. Unexpectedly, the number of infected enterocytes and the amount of RV shedding in the stool were greatly decreased following secretory cell deletion. Resistance to RV infection persisted for 7 days after virus inoculation, and Atoh1 knockout mice co-housed with infected wild-type mice were uninfected, …

Pskh1 Kinase Activity Is Differentially Modulated Via Allosteric Binding Of Ca2+ Sensor Proteins, Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley, Jared L Johnson, Tomer M Yaron-Barir, Emily M Huntsman, Leonard A Daly, Dominic P Byrne, Antonia L Cadell, Boaz H Ng, Jumana Yousef, Dylan H Multari, Lianju Shen, Luke M Mcaloon, Gerard Manning, Mark A Febbraio, Anthony R Means, Lewis C Cantley, Maria C Tanzer, David R Croucher, Claire E Eyers, Patrick A Eyers, John W Scott, James M Murphy

Children’s Nutrition Research Center Staff Publications

Protein Serine Kinase H1 (PSKH1) was recently identified as a crucial factor in kidney development and is overexpressed in prostate, lung, and kidney cancers. However, little is known about PSKH1 regulatory mechanisms, leading to its classification as a “dark” kinase. Here, we used biochemistry and mass spectrometry to define PSKH1’s consensus substrate motif, protein interactors, and how interactors, including Ca2+ sensor proteins, promote or suppress activity. Intriguingly, despite the absence of a canonical Calmodulin binding motif, Ca2+-Calmodulin activated PSKH1 while, in contrast, the ER-resident Ca2+ sensor of the Cab45, Reticulocalbin, Erc55, Calumenin (CREC) family, Reticulocalbin-3, suppressed PSKH1 catalytic activity. In …

Flow Dynamics Of Agricultural Waste Nanofibers: Shear, Temperature, And Oscillatory Insights, Bilge N. Altay, Burak Aksoy, James Atkinson, Christopher Lewis, Carlos Diaz-Acosta, Raymond Francis

Articles

The rheology and fiber size of corn stover (CS) and cleaned cotton gin trash (CGT) cellulose nanofibers (CNFs) were studied including behaviors at both moderate and extremely high shear rates, to simulate industrial processes ranging from mixing and pumping to high-speed coating, printing, and extrusion. Particle size analyzer showed that 99% of CS fibers measured around 226 nm, while 85% of CGT fibers were approximately 143 nm. Both CS and CGT CNFs formed gel-like suspensions, and shear flow tests revealed that all samples exhibited shear-thinning behavior, allowing easy flow under shear forces. Gels with higher solid content (1%) demonstrated extended …

Agouti And Bmp Signaling Drive A Naturally Occurring Fate Conversion Of Melanophores To Leucophores In Zebrafish, Delai Huang, Emaan H. Kapadia, Yipeng Liang, Leah P. Shriver, Shengkun Dai, Gary J. Patti, Bruno M. Humbel, Vincent Laudet, David M. Parichy

2020-Current year OA Pubs

No abstract provided.

From Privacy Litigation To Privacy Restoration: How To Manage The Questions Of How, When, And Whether. Case Note: Tr V. Land Hessen (Case C-768/21), Camilla Della Giustina

Plymouth Business School

The highest judicial body has recently hit the headlines. In TR v. Land Hessen, the Court of Justice of the EuropeanUnion (CJEU) has clarified the obligations incumbent on a supervisory authority pursuant to the General Data Protection Regulation (GDPR). The CJEU highlights that supervisory authorities are not obliged to exercise ‘corrective’ powers if not necessary to remedy the breach. It clarifies that under the GDPR, supervisory authorities have discretion in addressing the shortcomings of a supervised entity but must ensure compliance with a higher level of data protection.

Barriers To Nigerian Community Members In The United States Seeking Mental Health Treatment, Chinwendu Ejekwu

Walden Dissertations and Doctoral Studies

Nigerian immigrants in the United States face significant challenges in accessing mental health care due to various cultural and systemic barriers. This generic qualitative study, guided by Vygotsky’s sociocultural theory, was conducted to explore the barriers encountered by Nigerian community members in seeking mental health treatment in the United States. Data were obtained through semistructured interviews where nine Nigerian immigrants presented their perceptions and experiences concerning barriers to Nigerian community members seeking mental health treatment in the United States. Thematic analysis followed the six-step data analysis method, leading to three themes. The themes identified are: (a) mental health is a …

The Presidency, Press, And Public Opinion: Has The Relationship Between The Press And The Office Of The Presidency Shifted Since Trump’S Administration?, Jonas Kammeyer-Mueller

Scholarly Horizons: University of Minnesota, Morris Undergraduate Journal

In political science, studies focusing on the relationship between the press and the president have a long and rich history. However, few presidents have fought the press as strongly as Donald Trump. Given that many of these attacks utilized the influence afforded to Trump by occupying the Office of the Presidency, and that the press has long been noted to have influence over the public, it is worth examining if the relationship between the Office of the President and the press has shifted as a result of these attacks. Because the ability of the Presidency to govern as they wish …

Cultural Representations Of Obstetric Violence In Contemporary Italy, Veronica Frigeni

Journal of International Women's Studies

This article is the first examination of a hybrid corpus of cultural narratives of obstetric violence in contemporary Italy. Adopting a reproductive justice approach, the paper considers obstetric violence as gendered, intersectional, and ontological violence against reproductive subjects over the course of their lived reproductive experiences. Combining personal and cultural narratives, the article examines the 2022 comic “Da Che Mondo È Mondo,” written by Irene Caselli and illustrated by Rita Petruccioli, Alberto Basaluzzo’s 2018 short film Si È Sempre Fatto così, and Antonella Lattanzi’s 2023 novel Cose Che Non Si Raccontano to assess how and to what extent they …

He Is The Master Of Wood, Water, And Hill: Is Tom Bombadil The True Key Keeper Of The Old Forest?, Noelia Ramos

Journal of Tolkien Research

Tom Bombadil, with his iconic singing―”Hey! Come merry doll! Derry doll and merry-o!―has captivated scholars worldwide, due to the enigmatic nature Tolkien intentionally left unexplained. This deliberate mystery has fuelled extensive debate, leading many to explore possible mythological and cultural frameworks that might decode Bombadil’s origins. Among these hypotheses, a Celtic interpretation has often been dismissed despite its potential relevance. This paper, thereby, seeks to analyse Bombadil’s function within the Old Forest and his interactions with the hobbits during their forest episode, presenting fresh insights into his role as a Celtic-inspired guide and druidic figure.

To support this analysis, primary …

Legal Opportunities Solutions To Tackle The Deficit In Indonesia’S National Health Insurance Program, Diah Arimbi

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

No abstract provided.

Extraterritorial Act Versus The Indigenous People Protection: An Analysis Of The European Union Deforestation-Free Regulation, Aartje Tehupeiory, Putu George Matthew Simbolon

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

At first glance, indigenous people and international trade appear to be two separate issues. However, this perception does not apply in the case of European Regulation 2023/1115. This study aims to provide an understanding of how Indonesia should respond to the EU DFR, which has affected Indonesia’s national interests in protecting indigenous people. This study applied a normative method through doctrinal and conceptual approaches to achieve the objective. The study covers two main discussions. The first explains how due diligence under the EU DFR has indirectly pushed Indonesia to become an EU trading partner and provide more excellent protection for …

Questioning Food Security In Green Constitution Conception: Realizing Sustainable Development Goals (Sdgs) In Indonesia, Rahayu Subekti, Tsabbita Ahmilul Husna, Putri Balqis Salsabila

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Research on the constitution, food security, and sustainable development have become widely explored. However, issues related to the legal framework in the context of a green constitution remain unresolved. This is particularly evident in Indonesia’s efforts to address the food crisis, which has led to substantial deforestation. Therefore, this research aims to analyze the implementation of food security efforts in line with a green constitution in Indonesia. Despite the potential for adopting sustainability for future generations, there is hesitance in implementing articles related to a green constitution in food security activities. This legal issue is examined as normative research using …

Quasi-Contract: A Comparative Analysis Between The United States Of America And Indonesia, William Edward Sibarani, Utami Puspaningsih, Clarita Stefanie

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Since the Roman era, there has been a general consensus that no one should prosper at the expense of another. However, the development of variations in legal systems in the world means that many countries must continue to adapt to this situation to avoid legal loopholes. In certain situations, the complexity of obligations in society causes quasi-contracts to occur. As a country that follows the civil law constitutional framework, Indonesia still encounters difficulties in handling quasi-contract disputes, not only due to the absence of written regulations but also because previous court decisions do not bind Indonesia. In contrast, in the …

Realignment Of Flight Information Region Agreement Between Indonesia And Singapore 2022: Unraveling Sovereignty And Ratification Issues For Indonesia, Naufal Faiz Muhammad, Atip Latipulhayat, Garry Gumelar Pratama

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Flight Information Region (FIR) is an essential part of the aviation sector, providing air navigation and alerting services crucial for ensuring flight safety. States may delegate the management of FIR services to other nations for various reasons, primarily centered on aviation safety. However, such delegation requires careful consideration due to its potential impact on a state’s airspace sovereignty. This study focuses on the most recent FIR delegation involving the realignment of FIR over the Riau and Natuna Islands between Indonesia and Singapore in 2022. According to the signed agreement, Indonesia is obligated to delegate the management of specific areas of …

Sexual Abuse Of Street Children In Pakistan: Legal Protection Under International And National Law, Nazir Ullah, Saidatul Nadia Abd Aziz, Noor Aziah Mohd Awal

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

This study covers the social and legal dimensions of sexual abuse encountered by street children in Pakistan. It aims to elucidate the underlying reasons and contributory factors to child sexual abuse within the nation. This study employed qualitative methods, which involved analyzing data from primary sources such as acts of parliament and relevant journal articles. It highlights the exploitation of street children through prostitution, pornography, trafficking, and sex tourism. Therefore, it explored various manifestations of child sexual abuse both within street settings and beyond, alongside their foundational causes in Pakistani society. The study addresses the issue of sexual abuse among …

Democracy Crisis And The Rise Of Datacracy, Widodo Dwi Putro

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

There is no permanent constitutional and political-legal system. Scientists also predict that the phenomenon of the rise of datacracy with big data and algorithms will replace the democratic system. In this research, the author aims to answer the following questions: (i) Why is democracy bound to be replaced by datacracy? (ii) what alternative options can be proposed to bridge the legal and political implications that might occur if datacracy replaces democracy? The author uses literature studies and an interdisciplinary approach to critique and offer ideas in this study. It is proposed, among other things, that datacracy will not eliminate people's …

Digital Tax Regulation In Facing Society 5.0 Era To Realize Indonesian Tax Sovereignty, Amelia Cahyadini, Tasya Safiranita, Zainal Muttaqin, Rizki Fauzi, Ahmad M. Ramli

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Technological advancements have catalyzed the emergence of the digital economy, where digital platforms, leveraging internet access, can penetrate multiple regions and accrue substantial profits unrestricted by national jurisdictions. This scenario presents advantages and convenience but simultaneously challenges a country's tax sovereignty. The traditional tax system, predicated on a company's physical presence for tax liability, finds itself ill-equipped to handle the digital domain's nuances. This research seeks to explore the potential and hurdles in implementing digital taxes in Indonesia, delving into the government's regulatory efforts within the framework of Society 5.0. From an academic standpoint, digital taxes illustrate the disruption in …

The Inadequacy Of Legal Provisions On Workplace Sexual Harassment In Nigeria And Ghana: The Way Forward, Emuobo Emudainohwo

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Sexual harassment has been a persistent problem in workplaces in Nigeria and Ghana. The legal provisions in both jurisdictions generally focus on the definition of “sexual harassment” without remedies for the harassment, sanctions, enforcement procedures, anti-sexual harassment policies, complaint procedures, etc., that can control sexual harassment in the workplace. The article examines the scantiness and inadequacy of legal provisions on workplace sexual harassment in Nigeria and Ghana, suggesting a way forward. The doctrinal research method has been deployed, focusing on relevant Nigerian and Ghanaian legal provisions. The article considers the organization theory of sexual harassment, using it as a framework, …

A Discourse Of The Indigenous Peoples' Rights And Their Contributions To The Indonesian Development: Lessons Learned From New Zealand, Mohamad Jamin, Sapto Hermawan, Mulyanto Mulyanto

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The struggles of indigenous peoples in both New Zealand and Indonesia to gain legal recognition remain ongoing. This study focuses on two central aspects. Firstly, it examines the historical-legal journey of indigenous peoples in their quest for legal acknowledgment. Secondly, it makes a comparative analysis with New Zealand, highlighting the potential contributions that indigenous peoples can provide to their respective countries. The study follows a legal research methodology, linking existing issues with authoritative sources and real-world situations. The findings reveal that in New Zealand, indigenous peoples possess a legal standing, albeit not entirely comprehensive. Conversely, Indonesian regulations do not provide …

Resolving The Conflict Of Interests Issue Within The Laws Concerning The Political Matters: Deliberative Democracy Or Empowering Dewan Perwakilan Daerah?, Muhamad Dzadit Taqwa, Melinda Yunita Lasmaida Sirait, Ahmad Alfarizy

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

This study examines whether the concept of deliberative democracy could offer a viable solution to the issues surrounding laws on political matters, commonly referred to as Paket Undang-Undang Politik in Indonesia. These laws, including general election regulations, have become problematic due to their close association with the drafters. Over the past two decades, presidents and the majority in the House of Representatives have formed coalitions to maintain government stability. However, this success has had a detrimental impact on the system of checks and balances during the drafting of these laws. While the Constitutional Court could potentially intervene by reviewing these …

Developing Effective Procedures For Public Participation In Spatial Planning Regulation In Indonesia: Lesson Learned From Australia, I Gusti Ngurah Parikesit Widiatedja, Ida Bagus Erwin Ranawijaya, Sagung Putri Me Purwani, Bima Kumara Dwi Atmaja

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Public participation is a crucial aspect of spatial planning, serving to achieve sustainable development objectives. The Indonesian government has recognized this fact andincorporated public participation in its spatial planning lawsand regulations. However, procedures for involving the public have been criticized for lacking genuine participation, highlighting opportunities for public input only being offeredformally. Meanwhile, public participation is considered a significant component of spatial planning regulation in Australia, particularly in Victoria. The government has involved the public in various stages of the planning process, including creating a planning scheme, issuing planning permits, and completing planning agreements. Based on the established procedures under …

Dysfunctional Factors Of Environmental Law On Strategic Lawsuit Against Public Participation And Developing Remedial Strategies Through Reconstruction Criminal Law System Model In Indonesia, Hartiwiningsih Hartiwiningsih, Seno Wibowo Gumbira, Jaco Barkhuizen

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The excessive criminalization of community and environmental enforcement activists has prolonged the problem of SLAPP (Strategic Lawsuits Against Public Participation) in Indonesia. This study explores the factors contributing to non-optimal protection for citizens and environmental law enforcement activists. It aims to develop an ideal model for formulating the criminal law system to address Indonesia's Strategic Lawsuit Against Public Participation (SLAPP). This study used a doctrinal juridical approach to analyze and identify the factors preventing environmental law from effectively providing legal protection to the community and activists advocating for a good, healthy, and safe environment or the occurrence of SLAPP. This …

Theoretical Reconstruction Of The ’Existence Of The Indonesian Corruption Eradication Commission And Its Comparison To Other Anti-Corruption Agencies In Asia, Gunawan A. Tauda, Ni'matul Huda, Andy Omara

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Article 3 of the Indonesian Law Number 19 of 2019 stipulates that the Corruption Eradication Commission is a state institution within the executive power branch, which in carrying out its duties and authorities is independent and free from the influence of any power. The basic arrangement is not without problems, considering the institutional design of the Corruption Eradication Commission was initially stated in the Law Number 30 of 2002 “…a state institution, which in carrying out its duties and authorities is independent…,” becomes “…state institutions within the executive power branch….” The stipulation in Article 3, also the basic article of …

A Proposal To Adopt Concrete Judicial Review In Indonesian Constitutional Court: A Study On The German Federal Constitutional Court Experiences, Tanto Lailam, M. Lutfi Chakim

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The study aims to propose an adoption to concrete judicial review in Indonesian Constitutional Court based on the experiences of the German Federal Constitutional Court. It was motivated by the weak protection of citizen’s constitutional rights in ordinary court; and the absence of concrete judicial review authority at the Indonesian Constitutional Court. This study used doctrinal legal research method with legal documents or regulations, cases, and comparative analyses. This concrete review confirms the role of judges of ordinary courts in proceeding with the constitutional system, especially in protecting fundamental rights from the legislatures’ law violations based on Articles 93, 94, …

The Opportunities For Surrogacy Legalization Between The Right To Have Children And A Loophole Of Trafficking, Wawan Edi Prastiyo, Gde Made Swardhana

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The phenomenon of producing surrogate mother facilities has been recognized in some countries, although Indonesia indirectly prohibits the practice. The practice is also feared to be a new form of human trafficking. Therefore, this study aims to evaluate the opportunities for surrogacy legalization regarding its perspectives between human rights and the loophole of trafficking. In this study, three problems were formulated: (1) the legal status of children born from a surrogate mother; (2) the legality of a surrogate mother in Indonesian law; and (3) the opportunities for surrogacy legalization in legal reform. This study is a normative juridical study that …

The Indonesian President’S Prerogative Rights In The Appointment Of Ministers After The Amendment To The 1945 Constitution, Isnawati Isnawati, Adam Setiawan, Fatma Hidayati, Rezky Robiatul Aisyiah Ismail

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The president possesses the prerogative right to appoint and dismiss his government personnel without having to seek approval from other branches of power. In practice, the president often does not use the rightfully because of the coalition consequences of the multiparty party system, which also has implications for the practice of appointing ministers and deputy ministers. Therefore, the president is not independent to choose figures for strategic political positions. This study examined the Indonesian president's prerogative right in appointing ministers after the amendment to the 1945 Constitution. This study used doctrinal legal research with statutory regulations, conceptual approaches, and comparative …

A Comparison Between Indonesian And Malaysian Anti-Corruption Laws, Tinuk Dwi Cahyani, Muhamad Helmi Md Said, Muhamad Sayuti Hassan

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Corruption is quite a complicated problem. It has made many countries, including Indonesia, to ratify the United Nations Convention Against Corruption (UNCAC). It is an effort to prevent and to eradicate corruption with international cooperation. Unfortunately, several studies have revealed that Indonesia is experiencing a legal vacuum on corruption because Indonesia only adopts a few points of the United Nations Convention Against Corruption in written regulations. The legal vacuum causes difficulties in the resolution of corruption cases. Compared to other countries, the Indonesia Corruption Perceptions Index is still quite high. It leads to some questions that are addressed in this …

Treaties As A Source Of National Law In The Perspective Of Constitutional Law, Efik Yusdiansyah, Wicaksana Dramanda

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The 1945 Constitution of the Republic of Indonesia does not regulate the relations and interactions between treaties and national law. The absence of constitutional norms regarding this matter raises the question of how treaties become a source of national law. This study puts forward the perspective of constitutional law to answer how national law perceives treaties in the dimensions of national law. It argues that the constitutional law paradigm views treaties as a product of the legislative and executive interaction within the framework of the theory of separation of powers. Based on this view, the formation of law is the …

The Renewal Policy Of The Adultery Concept In Article 411 Of The Law Number 1 Of 2023 On The Indonesian Criminal Code, Mas Putra Zenno Januarsyah, Dwidja Priyatno, Somawijaya Somawijaya, Widiada Gunakaya

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

At present, Indonesia needs to update the Indonesian Criminal Code to replace the Dutch Colonial Criminal Code that still exists. The jurists, especially criminal law experts, have been involved in a lengthy debate on overhauling, reformulating, revising, and even reforming the Criminal Code to align with Indonesian values. This study aims to determine the foundation of the policy to expand the concept of adultery and the values protected by the expansion contained in Article 411 of Law Number 1 of 2023 on the Criminal Code. This study was a descriptive study that used a normative juridical approach. The data collection …

The European Union Charter Of Fundamental Rights: Strengthening The Participation In The European Union, Adnan Mahmutovic

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

This study employed legal and political analysis to assess the significance of the European Union Charter of Fundamental Rights to strengthen the democratic legitimacy of the European Union. There is a lack of comprehensive analysis of the contribution of the European Union Charter of Fundamental Rights to enhance the democratic legitimacy of the European Union. Therefore, this study tried to address the gap by focusing on specific provisions of the Charter that are designed to promote participatory democracy and to foster a closer relationship between the citizens and the European Union. The study also explored the legal challenges and complexities …