Digital Commons Network^™

Lbsci 700 / Info 7001. The Technology Of Information., Brandon K. Jeffries Mr.

Open Educational Resources

This course will introduce the student to the conceptual and practical elements of visual and computer literacy for the library and information science profession. Particular attention will be paid to the place and role of libraries and information centers. A laboratory session following each class will give students the opportunity to apply some of the concepts learned in class.

German 250w: Weimar German Cinema, Christa Spreizer

Open Educational Resources

German 250W (German Film and Media) analyzes various iconic Weimar German silent and sound films of the early 20th century such as The Cabinet of Dr. Caligari, Nosferatu, The Nibelungen, Metropolis, M, Dr. Mabuse, Blue Angel and others. We will analyze the extraordinary development of German cinema during a period of great political and economic instability, and an all-encompassing cultural revival.

Clinical And Genetic Delineation Of Autosomal Recessive And Dominant Actl6b-Related Developmental Brain Disorders., Elisa Cali, Tania Quirin, Clarissa Rocca, Stephanie Efthymiou, Antonella Riva, Dana Marafi, Maha S. Zaki, Mohnish Suri, Roberto Dominguez, Hasnaa M. Elbendary, Shahryar Alavi, Mohamed S. Abdel-Hamid, Heba Morsy, Frederic Tran Mau-Them, Mathilde Nizon, Pavel Tesner, Lukáš Ryba, Faisal Zafar, Nuzhat Rana, Nebal W. Saadi, Zahra Firoozfar, Pinar Gencpinar, Bulent Unay, Canan Ustun, Ange-Line Bruel, Christine Coubes, Jennifer Stefanich, Ozlem Sezer, Emanuele Agolini, Antonio Novelli, Gessica Vasco, Donatella Lettori, Mathieu Milh, Laurent Villard, Shimriet Zeidler, Henry Opperman, Vincent Strehlow, Mahmoud Y Issa, Hebatallah El Khassab, Prem Chand, Shahnaz Ibrahim, Ali Rashidi-Nezhad, Mohammad Miryounesi, Pegah Larki, Jennifer Morrison, Ingrid Cristian, Isabelle Thiffault, Nicole L. Bertsch, Grace J. Noh, John Pappas, Ellen Moran, Nikolaos M. Marinakis, Joanne Traeger-Synodinos, Susan Hosseini, Mohammad Reza Abbaszadegan, Roseline Caumes, Lisenka E L M Vissers, Maedeh Neshatdoust, Mostafa Montazer Zohour, Elmostafa El Fahime, Christina Canavati, Lara Kamal, Moien Kanaan, Omar Askander, Victoria Voinova, Olga Levchenko, Shahzhad Haider, Sara S. Halbach, Rayana Elias Maia, Salehi Mansoor, Vivek Jain, Sanjukta Tawde, Viveka Santhosh R. Challa, Vykuntaraju K. Gowda, Varunvenkat M. Srinivasan, Lucas Alves Victor, Benito Pinero-Banos, Jennifer Hague, Heba Ahmed Elawady, Adelia Maria De Miranda Henriques-Souza, Huma Arshad Cheema, Muhammad Nadeem Anjum, Sara Idkaidak, Firas Alqarajeh, Osama Atawneh, Hagar Mor-Shaked, Tamar Harel, Giovanni Zifarelli, Peter Bauer, Fernando Kok, Joao Paulo Kitajima, Fabiola Monteiro, Juliana Josahkian, Gaetan Lesca, Nicolas Chatron, Dorothe Ville, David Murphy, Jeffrey L. Neul, Sureni V. Mullegama, Amber Begtrup, Isabella Herman, Tadahiro Mitani, Jennifer E. Posey, Chee Geap Tay, Iram Javed, Lucinda Carr, Farah Kanani, Fiona Beecroft, Lee Hane, Elsayed Abdelkreem, Milan Macek, Luciana Bispo, Marwa Abd Elmaksoud, Farzad Hashemi-Gorji, Davut Pehlivan, David J. Amor, Rami Abou Jamra, Wendy K. Chung, Eshan Ghayoor Karimiani, Philippe M. Campeau, Fowzan S. Alkuraya, Alistair T. Pagnamenta, Joseph G. Gleeson, James R. Lupski, Pasquale Striano, Andres Moreno-De-Luca, Denis L J Lafontaine, Henry Houlden, Reza Maroofian

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: This study aims to comprehensively delineate the phenotypic spectrum of ACTL6B-related disorders, previously associated with both autosomal recessive and autosomal dominant neurodevelopmental disorders. Molecularly, the role of the nucleolar protein ACTL6B in contributing to the disease has remained unclear.

METHODS: We identified 105 affected individuals, including 39 previously reported cases, and systematically analyzed detailed clinical and genetic data for all individuals. Additionally, we conducted knockdown experiments in neuronal cells to investigate the role of ACTL6B in ribosome biogenesis.

RESULTS: Biallelic variants in ACTL6B are associated with severe-to-profound global developmental delay/intellectual disability, infantile intractable seizures, absent speech, autistic features, dystonia, …

Ritual As Resistance: Orality, Identity, And Soviet Kazakh Childhood In Sayin Muratbekov’S The Smell Of Wormwood, Dana Akhmerova

Comparative Literature M.A. Essays

This essay analyzes The Smell of Wormwood (1967), a short novel by Soviet Kazakh author Sayin Muratbekov, set in a Kazakh village during World War II. The narrative centers on Ayan, a nine-year-old orphan with a physical disability, who copes with trauma and marginalization by becoming a storyteller for the village children. Focusing on the role of Kazakh folklore—particularly storytelling and initiation rituals—I explore how these cultural forms shape the novel’s characters, structure, and central conflict. Drawing on Arnold van Gennep and Victor Turner’s theories of ritual, I argue that Ayan’s storytelling creates an informal liminal space through which the …

Beware The Wandering Woman: Depictions Of Female Spatial Transgression In Athenian Public Dramas Of The 5th And 4th Centuries Bce, Anne E. Mcgrath

Comparative Literature M.A. Essays

This paper explores how ancient Greek literature and culture construct autonomous, mobile women as threats to the ideological and spatial order of the polis. Referencing mythological precedents and closely reading Classical texts, I propose the category of “excepted women” to address the threads of female transgression woven throughout this extensive literary corpus. Focusing on figures who transgress imposed spatial boundaries, I examine how such women are positioned as disruptors of gendered norms and civic stability, thus reflecting deep cultural anxieties about female agency and movement into spaces coded as masculine. The paper engages theoretical frameworks from Althusser and Butler to …

When Reading For The Plot Goes Wrong: “Death And The Compass” (“La Muerte Y La BrúJula”) By Jorge Luis Borges (1899-1986) And “The Sunglasses Society” (《眼镜会》) By Sun Liaohong (1897-1958), Reuben Slade

Comparative Literature M.A. Essays

Detective fiction was once considered the pulpy, mass-consumed genre of a newly literate class with unrefined taste and an unquenchable desire for temporary withdrawal from the chaotically modernizing urban centers of the early 20th century. It has since transcended national boundaries to become a fully potentiated sect of world literature. As it traveled the world, local additions that imitated a recognizable form were imbued with distinct locality– detective fiction became both global and local, undertaking the universal questions of morality, law, order, and modernity in juxtaposition with the domestic circumstances that complicated them. This presentation places two detective stories in …

In Sickness And In Health: Care And Complacency In Aid Efforts For Migrant Youth In Eastern France, Nzana K. Thillot , '25

Senior Theses, Projects, and Awards

This thesis examines the perspectives of educators working with unaccompanied migrant minors (MNAs) in eastern France, focusing on how they perceive and navigate the care system and creates their own communities of care within the gaps of the bureaucratic French system. Through qualitative analysis, it explores how educators interpret the structural challenges MNAs face, including access to healthcare, social integration, and legal protections. By centering educators’ voices, this study highlights their role as intermediaries between MNAs and the French system that determines their access to essential services. It interrogates how these professionals negotiate institutional constraints, advocate for the well-being and …

You Thought You Ate: How Capitalism Constructs Black Women’S Body Image And Relationship To Food, Nia Y. Todd , '25

Senior Theses, Projects, and Awards

No abstract provided.

New Onset Refractory Status Epilepticus: Long-Term Outcomes Beyond Seizures, Poul H Espino, Krista Eschbach, Leah J Blank, Mackenzie C Cervenka, Eyal Muscal, Raquel Farias-Moeller, Emily J Gilmore, Margaret T Gopaul, Hiba A Haider, Aurelie Hanin, Lawrence J Hirsch, Marissa A Kellogg, Gerhard Kluger, Soon-Tae Lee, Alexandria E Melendez-Zaidi, Vincent Navarro, Audrey C Oliger, Elena Pasini, Gitta Reuner, Cynthia M Sharpe, Zubeda B Sheikh, Leon Steigleder, Claude Steriade, Coral M Stredny, Adam Strzelczyk, Olga Taraschenko, Andreas Van Baalen, Sarah A Vinette, Ronny Wickström, Nora W Wong, Jiyeoun Yoo, Teneille E Gofton

Faculty, Staff and Students Publications

We propose and prioritize important outcome domains that should be considered for future research investigating long-term outcomes (LTO) after new onset refractory status epilepticus (NORSE). The study was led by the international NORSE Institute LTO Working Group. First, literature describing the LTO of NORSE survivors was identified using a PubMed search and summarized to identify knowledge gaps. Subsequently, a consensus-building process was performed to prioritize and rank important LTO domains for further research. The prioritization of LTO domains was qualitative, enabling the expert panel to generate ideas, share opinions, and provide reasons for the rankings. A second round took place …

Intestinal Epithelial Serotonin As A Novel Target For Treating Disorders Of Gut-Brain Interaction And Mood, Lin Y Hung, Nuno D Alves, Andrew Del Colle, Ardesheer Talati, Sarah A Najjar, Virginie Bouchard, Virginie Gillet, Yan Tong, Zixing Huang, Kirsteen N Browning, Jialiang Hua, Ying Liu, James O Woodruff, Daniel Juarez, Melissa Medina, Jonathan Posner, Raquel Tonello, Nazli Yalcinkaya, Narek Israelyan, Roey Ringel, Letao Yang, Kam W Leong, Mu Yang, Ji Ying Sze, Tor Savidge, Jay Gingrich, Robert J Shulman, Michael D Gershon, Annie Ouellet, Larissa Takser, Mark S Ansorge, Kara Gross Margolis

Faculty, Staff and Students Publications

Background & aims: Mood disorders and disorders of gut-brain interaction (DGBI) are highly prevalent, commonly comorbid, and lack fully effective therapies. Although selective serotonin reuptake inhibitors (SSRIs) are first-line pharmacological treatments for these disorders, they may impart adverse effects, including anxiety, anhedonia, dysmotility, and, in children exposed in utero, an increased risk of cognitive, mood, and gastrointestinal disorders. SSRIs act systemically to block the serotonin reuptake transporter and enhance serotonergic signaling in the brain, intestinal epithelium, and enteric neurons. Yet, the compartments that mediate the therapeutic and adverse effects of SSRIs are unknown, as is whether gestational SSRI exposure directly …

Alert Design In The Real World: A Cross-Sectional Analysis Of Interruptive Alerting At 9 Academic Pediatric Health Systems, Swaminathan Kandaswamy, Julia K W Yarahuan, Elizabeth A Dobler, Matthew J Molloy, Lindsey A Knake, Sean M Hernandez, Anne A Fallon, Lauren M Hess, Allison B Mccoy, Regine M Fortunov, Eric S Kirkendall, Naveen Muthu, Evan W Orenstein, Adam C Dziorny, Juan D Chaparro

Faculty, Staff and Students Publications

Objective: To assess the prevalence of recommended design elements in implemented electronic health record (EHR) interruptive alerts across pediatric care settings.

Materials and methods: We conducted a 3-phase mixed-methods cross-sectional study. Phase 1 involved developing a codebook for alert content classification. Phase 2 identified the most frequently interruptive alerts at participating sites. Phase 3 applied the codebook to classify alerts. Inter-rater reliability (IRR) for the codebook and descriptive statistics for alert design contents were reported.

Results: We classified alert content on design elements such as the rationale for the alert's appearance, the hazard of ignoring it, directive versus informational content, …

Klf4 Enhances Transplantation-Induced Hematopoiesis By Inhibiting Tlrs And Noncanonical Nfκb Signaling At A Steady State, Chun Shik Park, Cory S Bridges, Andrew H Lewis, Taylor J Chen, Saptarsi Shai, Wa Du, Monica Puppi, Barry Zorman, Sumazin Pavel, H Daniel Lacorazza

Faculty, Staff and Students Publications

The transcription factor Krüppel-like factor 4 (KLF4) acts as a transcriptional activator and repressor. KLF4 plays a role in various cellular processes, including the dedifferentiation of somatic cells into induced pluripotent stem cells. Although it has been shown to enhance self-renewal in embryonic and leukemia stem cells, its role in adult hematopoietic stem cells (HSCs) remains underexplored. We demonstrate that conditional deletion of the Klf4 gene in hematopoietic cells led to an increased frequency of immunophenotypic HSCs in the bone marrow, along with a normal distribution of lymphoid and myeloid progenitor cells. Noncompetitive bone marrow transplants showed normal engraftment and …

Atrial Cardiomyocyte-Restricted Cleavage Of Gasdermin D Promotes Atrial Arrhythmogenesis, Yue Yuan, Pascal Martsch, Xiaohui Chen, Enrique Martinez, Luge Li, Jia Song, Theresa Poppenborg, Florian Bruns, Jong Hwan Kim, Markus Kamler, James F Martin, Issam Abu-Taha, Dobromir Dobrev, Na Li

Faculty, Staff and Students Publications

Background and aims: Enhanced inflammatory signalling causally contributes to atrial fibrillation (AF) development. Gasdermin D (GSDMD) is an important downstream effector of several inflammasome pathways. However, the role of GSDMD, particularly the cleaved N-terminal (NT)-GSDMD, in non-immune cells remains elusive. This study aimed to elucidate the function of NT-GSDMD in atrial cardiomyocytes (ACMs) and determine its contribution to atrial arrhythmogenesis.

Methods: Human atrial appendages were used to assess the protein levels and localization. A modified adeno-associated virus 9 was employed to establish ACM-restricted overexpression of NT-GSDMD in mice.

Results: The cleavage of GSDMD was enhanced in ACMs of AF patients. …

Addressing The Burden Of Steatotic Liver Disease: The Role Of Transient Elastography: Correspondence To Editorial On “Current Burden Of Steatotic Liver Disease And Fibrosis Among Adults In The United States, 2017–2023”, Donghee Kim, Pojsakorn Danpanichkul, Karn Wijarnpreecha, George Cholankeril, Rohit Loomba, Aijaz Ahmed

Faculty, Staff and Students Publications

No abstract provided.

Insights Into Protection Against Mycobacterium Tuberculosis Infection: Time To Officially Confirm Another Phenotype?, Todia P Setiabudiawan, Philip C Hill, Andrew R Dinardo, Reinout Van Crevel

Faculty, Staff and Students Publications

Immune correlates of protection against infection with Mycobacterium tuberculosis (Mtb) remain elusive. In this issue of the JCI, Dallmann-Sauer and authors demonstrate that lack of tuberculin skin test (TST) and interferon γ release assay (IGRA) conversion among people with HIV despite years-long Mtb exposure is associated with alveolar lymphocytosis, including specific poly-cytotoxic T cells, and M1-type alveolar macrophages with a stronger ex vivo response to the pathogen. Studies in these rare individuals, termed "TB resisters" and in tuberculosis household contacts who are repeatedly IGRA negative in the months after a specific exposure event (known as "early clearers") help elucidate manipulatable …

Clinical And Genetic Delineation Of Autosomal Recessive And Dominant Actl6b-Related Developmental Brain Disorders, Elisa Cali, Tania Quirin, Clarissa Rocca, Stephanie Efthymiou, Antonella Riva, Dana Marafi, Maha S Zaki, Mohnish Suri, Roberto Dominguez, Hasnaa M Elbendary, Shahryar Alavi, Mohamed S Abdel-Hamid, Heba Morsy, Frederic Tran Mau-Them, Mathilde Nizon, Pavel Tesner, Lukáš Ryba, Faisal Zafar, Nuzhat Rana, Nebal W Saadi, Zahra Firoozfar, Pinar Gencpinar, Bulent Unay, Canan Ustun, Ange-Line Bruel, Christine Coubes, Jennifer Stefanich, Ozlem Sezer, Emanuele Agolini, Antonio Novelli, Gessica Vasco, Donatella Lettori, Mathieu Milh, Laurent Villard, Shimriet Zeidler, Henry Opperman, Vincent Strehlow, Mahmoud Y Issa, Hebatallah El Khassab, Prem Chand, Shahnaz Ibrahim, Ali Rashidi-Nezhad, Mohammad Miryounesi, Pegah Larki, Jennifer Morrison, Ingrid Cristian, Isabelle Thiffault, Nicole L Bertsch, Grace J Noh, John Pappas, Ellen Moran, Nikolaos M Marinakis, Joanne Traeger-Synodinos, Susan Hosseini, Mohammad Reza Abbaszadegan, Roseline Caumes, Lisenka E L M Vissers, Maedeh Neshatdoust, Mostafa Montazer Zohour, Elmostafa El Fahime, Christina Canavati, Lara Kamal, Moien Kanaan, Omar Askander, Victoria Voinova, Olga Levchenko, Shahzhad Haider, Sara S Halbach, Rayana Elias Maia, Salehi Mansoor, Vivek Jain, Sanjukta Tawde, Viveka Santhosh R Challa, Vykuntaraju K Gowda, Varunvenkat M Srinivasan, Lucas Alves Victor, Benito Pinero-Banos, Jennifer Hague, Heba Ahmed Elawady, Adelia Maria De Miranda Henriques-Souza, Huma Arshad Cheema, Muhammad Nadeem Anjum, Sara Idkaidak, Firas Alqarajeh, Osama Atawneh, Hagar Mor-Shaked, Tamar Harel, Giovanni Zifarelli, Peter Bauer, Fernando Kok, Joao Paulo Kitajima, Fabiola Monteiro, Juliana Josahkian, Gaetan Lesca, Nicolas Chatron, Dorothe Ville, David Murphy, Jeffrey L Neul, Sureni V Mullegama, Amber Begtrup, Isabella Herman, Tadahiro Mitani, Jennifer E Posey, Chee Geap Tay, Iram Javed, Lucinda Carr, Farah Kanani, Fiona Beecroft, Lee Hane, Elsayed Abdelkreem, Milan Macek, Luciana Bispo, Marwa Abd Elmaksoud, Farzad Hashemi-Gorji, Davut Pehlivan, David J Amor, Rami Abou Jamra, Wendy K Chung, Eshan Ghayoor Karimiani, Philippe M Campeau, Fowzan S Alkuraya, Alistair T Pagnamenta, Joseph G Gleeson, James R Lupski, Pasquale Striano, Andres Moreno-De-Luca, Denis L J Lafontaine, Henry Houlden, Reza Maroofian

Faculty, Staff and Students Publications

Purpose: This study aims to comprehensively delineate the phenotypic spectrum of ACTL6B-related disorders, previously associated with both autosomal recessive and autosomal dominant neurodevelopmental disorders. Molecularly, the role of the nucleolar protein ACTL6B in contributing to the disease has remained unclear.

Methods: We identified 105 affected individuals, including 39 previously reported cases, and systematically analyzed detailed clinical and genetic data for all individuals. Additionally, we conducted knockdown experiments in neuronal cells to investigate the role of ACTL6B in ribosome biogenesis.

Results: Biallelic variants in ACTL6B are associated with severe-to-profound global developmental delay/intellectual disability, infantile intractable seizures, absent speech, autistic features, dystonia, …

Words Matter: Destigmatizing The Language Of Medicine Through Research, Training, And Future Directions For Emergency Medicine, Natalie Strokes, Richard Sapp, Meta Carroll, Elizabeth Maxwell Hovis, Mary Mclean, Shannon Markus, Aaryn Hammond, Rosemarie Diaz, Ryan E Tsuchida, Marcia Perry, Edgardo Ordonez

Faculty, Staff and Students Publications

Background: In emergency medicine (EM), language choice significantly impacts patient care and can potentially cause harm, dehumanize patients, and introduce bias. Stigmatizing language in medical settings can affect patient dignity, trust, and outcomes. Despite its importance, there is limited education on avoiding stigmatizing language in EM. This concept paper addresses the need to raise awareness and develop strategies for use of inclusive language in the emergency department (ED).

Methods: A didactic session titled "Words Matter: Destigmatizing the Language of Medicine" was developed and presented at the 2024 Society for Academic Emergency Medicine (SAEM) Annual Meeting. The session involved a collaborative …

Systemic Aging Fuels Heart Failure: Molecular Mechanisms And Therapeutic Avenues, Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li

Faculty, Staff and Students Publications

Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac amyloidosis, elevating susceptibility to chronic heart failure (HF) in the elderly. Age-related cardiac dysfunction stems from prolonged exposure to genomic, epigenetic, oxidative, autophagic, inflammatory and regenerative stresses, along with the accumulation of senescent cells. Concurrently, age-related structural and functional changes in the vascular system, attributed to endothelial dysfunction, arterial stiffness, impaired angiogenesis, oxidative stress and inflammation, impose additional …

Measuring The Extent Of Cyberbullying Comments In Facebook Groups For Mosul University Students, Kanaan J. Brakas, Mafaz Alanezi

Mesopotamian Journal of CyberSecurity

The widespread utilization of social media platforms such as Facebook, Twitter, and Instagram inside academic organizations has become fundamental for student correspondence and joint effort, yet it has simultaneously prompted an increase in cyberbullying incidents. Cyberbullying is embodied by offensive and harmful comments that sabotage the casualty's prosperity. This study plans to resolve this issue by fostering an extensive module to distinguish cases of cyberbullying inside Facebook groups of Mosul University students. Our methodology starts with the collection of data in the Arabic language, which is then exposed to careful manual handling to label comments and eliminate clamor-like copies and …

Developing And Validating Brain Tumor Organoid Models To Evaluate Novel Therapeutics In Vitro, Dev P. Patel

Senior Theses

Glioblastoma (GBM), a World Health Organization Grade IV brain tumor, remains one of the most aggressive and treatment-resistant malignancies. It is characterized by rapid proliferation, deep infiltration, and a high level of genotypic and phenotypic heterogeneity. Despite advancements in medical technology and neuro-oncology, GBM remains one of the most treatment-resistant cancers with a median survival rate of only nine months post-diagnosis and less than 5% of patients surviving beyond 5 years of diagnosis. The standard treatment constitutes maximum surgical resection followed by chemotherapy and radiation. These therapeutic strategies are blocked by significant challenges like the blood-brain barrier (BBB), and intratumoral …

The Idea Of Inclusivity: The Fallacy Of School Choice, Harleigh Summerville

Arkansas Law Notes

As calls for reform in public education grow, students with disabilities have become the poster children for a failing system that is not equipped to handle students’ varying needs. With the number of children receiving services for learning disabilities growing, some argue that the current system not only is failing to provide students with appropriate education but is actively causing harm. Issues gaining adequate funding, disparities in educational access to racial minorities, and failure to adhere to federal mandates have made it difficult for public schools to meet the individualized needs of all students, particularly students with disabilities. One example …

The Two Men Named Perez Andrews Of Oxford County, Maine, Kathrine C. Aydelott

Faculty Publications

This article resolves a long-standing genealogical confusion between two men named Perez (or Peres) Andrews, whose overlapping names, lifespans, and locations in 19th-century Maine have led to persistent misidentification in published genealogies and family trees. Drawing on extensive primary source research—including land records, censuses, court cases, and vital records—this study reconstructs the distinct lives of Perez Andrews (b. ca. 1767) of Bakerstown, Minot, Buckfield, and Bradford, Maine; and Peres Andrews (b. 1797) of No. 2 Plantation and Sumner. The paper not only separates their identities and lineages but also probes possible familial connections among the Andrews families of western Maine. …

Material Point Method Computer Simulations Of The Tharsis Region Mars Forming From An Impact-Driven Antipodal Event: Program Development And Validation, Timothy L. Nikoley, Daniel Hunter, Michael W. Roth

The Compass: Earth Science Journal of Sigma Gamma Epsilon

The planet Mars has features that suggest uprisings could have been created by antipodal events driven by the focusing of seismic waves generated by impact. To investigate the feasibility of such a process resulting in observed features, we have developed a hybrid Newtonian dynamics-Material Point Method (MPM) computer program modeling impact to the surface of Mars, and have carried out extensive computer simulations and data analysis. In this first of two companion papers, we present the theoretical background behind the code development, remarks about program validation and typical visuals.

The Compass - Volume 94 Issue 2 - Complete Issue, Scott R. Beason

The Compass: Earth Science Journal of Sigma Gamma Epsilon

No abstract provided.

Police Officers’ Use Of Force In The Low Country Of South Carolina, Mariah Roy

Walden Dissertations and Doctoral Studies

United States police officers' use of force is an ongoing concern of many community members. As these encounters continue to occur, lawmakers in states, including South Carolina (SC), have revitalized or implemented statutes addressing the use of force. The purpose of this qualitative phenomenological study was to better understand the use of force in law enforcement from the perspectives of community members in the Low Country region of SC. The rational model and contact hypothesis served as the study’s foundation. Data were collected from interviews with 10 participants over the age of 18 from Charleston, SC, a city within the …

Arab Americans’ Views Of Arab Lobbying Efforts Related To The Palestinian-Israeli Conflict, Samar Farha

Walden Dissertations and Doctoral Studies

Research on ethnic lobbying has largely neglected the perspectives of Arab Americans, creating a disconnect between this community and their lobbying efforts. This gap is crucial because it threatens to widen the disconnect between Arab Americans and their lobbying groups, where effective lobbying depends on a unified message. Existing studies highlight this gap, pointing out the lack of unified organization and ongoing resource constraints that limit the influence of Arab American lobbyists on U.S. foreign policy. The purpose of this generic qualitative was to explore Arab Americans’ perceptions of their lobbying efforts and the factors shaping these perceptions based on …

Disabled And Disenfranchised: The Fight For Reproductive Freedom And Democracy Post-Dobbs, Robyn M. Powell

Cardozo Law Review

The Supreme Court has thrust abortion onto ballots nationwide, transforming fundamental rights into political battlegrounds. In the aftermath of Dobbs v. Jackson Women's Health Organization, people with disabilities face a perfect storm of eroded reproductive freedoms and persistent barriers to democratic participation. This Article exposes the hollow promise of the Court's purported deference to "the people's elected representatives," revealing instead a landscape where those most affected by abortion restrictions struggle to have their voices heard. The Court's invocation of democracy is arguably disingenuous, serving more as a rhetorical device than agenuine commitment to democratic principles. Nevertheless, engaging with this …

The Truth Should Set You Free: The Case For Removing State Knowledge Requirements From False Testimony Standards, Alexa Pietrowsk

Cardozo Law Review

False testimony claims are an increasinglypopular vehicle in a handful ofstates through which petitioners can challenge unconstitutional criminal convictions. Successful false testimony claims grant petitioners access to remedies guaranteed by the Due Process Clause and overturn offending convictions, giving individuals access to new trials or similar relief But like many post-conviction standards, false testimony is evaluated differently from state to state, producing disparate results. While every state's standard requires that the testimony used at trial be proven both false and material to the petitioner's conviction, states diverge as to whether petitioners must show that a state actor-usually prosecutors or police-knew …

Development Of Real-Time Threat Detection Systems With Ai-Driven Cybersecurity In Critical Infrastructure, Noora Zidan Khalaf, Israa Ibraheem Al Barazanchi, Israa Ibraheem Al Barazanchi, A. D. Radhi, A. D. Radhi, Pritesh Shah, Ravi Sekhar

Mesopotamian Journal of CyberSecurity

Protection of infrastructure is becoming increasingly demanding, and the sophistication and severity of cyber threats are increasing daily. Traditional threat detection techniques cannot match the ever-evolving nature of cyber threats, which increases the number of false positives and attack misses. AI-driven methods address these shortfalls via the use of advanced learning algorithms to detect and respond to newly discovered threats in real time. They are largely static rule-based or signature-based attacks, and they do not perform effectively against zero-day attacks and highly organized, advanced attacks. Given the critical need to protect digital infrastructures such as energy, transport, and communications from …

Alphafold 3, Ai, Antibody Patents, The Future Of Broad Pharmaceutical Patent Claims, And Drug Development, Brendan Bargmann, Robert A. Bohrer

Faculty Scholarship

Artificial intelligence (AI) will have an enormous impact both on pharmaceutical development and patent protection, particularly for antibody therapeutics. In Amgen Inc. v. Sanofi, the U.S. Supreme Court limited the scope of Amgen’s therapeutic antibody patent to only those antibodies that were specifically described in Amgen’s patent application and that had been shown to bind to a particular region of the target antigen, blocking the activity of the antigen that caused disease. The reason for this limitation was the patent requirement of enablement: that potentially millions of antibodies could be generated to the target antigen but that not all …