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Prove Me Wrong Cases And Consideration Theory, Daniel P. O'Gorman Jan 2015

Prove Me Wrong Cases And Consideration Theory, Daniel P. O'Gorman

Faculty Scholarship

No abstract provided.

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Redox Regulation Of Nlrp3 Inflammasomes: Ros As Trigger Or Effector?, Justine M. Abais, Min Xia, Yang Zhang, Krishna M. Boini, Pin-Lan Li Jan 2015

Redox Regulation Of Nlrp3 Inflammasomes: Ros As Trigger Or Effector?, Justine M. Abais, Min Xia, Yang Zhang, Krishna M. Boini, Pin-Lan Li

Pharmacology and Toxicology Publications

Significance: Inflammasomes are multiprotein complexes localized within the cytoplasm of the cell that are responsible for the maturation of proinflammatory cytokines such as interleukin-1β (IL-1β) and IL-18, and the activation of a highly inflammatory form of cell death, pyroptosis. In response to infection or cellular stress, inflammasomes are assembled, activated, and involved in host defense and pathophysiology of diseases. Clarification of the molecular mechanisms leading to the activation of this intracellular inflammatory machinery may provide new insights into the concept of inflammation as the root of and route to human diseases. Recent Advances: The activation of inflammasomes, specifically the most …

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Integrating Mrna And Mirna Weighted Gene Co-Expression Networks With Eqtls In The Nucleus Accumbens Of Subjects With Alcohol Dependence, Mohammed Mamdani, Vernell Williamson, Gowon O. Mcmichael, Tana Blevins, Fazil Aliev, Amy Adkins, Laura Hack, Tim Bigdeli, Andrew D. Van Der Vaart, Bradley Todd Webb, Silviu-Alin Bacanu, Gursharan Kalsi, Coga Consortium, Kenneth S. Kendler, Michael F. Miles, Danielle Dick, Brien P. Riley, Catherine Dumur, Vladimir I. Vladimirov Jan 2015

Integrating Mrna And Mirna Weighted Gene Co-Expression Networks With Eqtls In The Nucleus Accumbens Of Subjects With Alcohol Dependence, Mohammed Mamdani, Vernell Williamson, Gowon O. Mcmichael, Tana Blevins, Fazil Aliev, Amy Adkins, Laura Hack, Tim Bigdeli, Andrew D. Van Der Vaart, Bradley Todd Webb, Silviu-Alin Bacanu, Gursharan Kalsi, Coga Consortium, Kenneth S. Kendler, Michael F. Miles, Danielle Dick, Brien P. Riley, Catherine Dumur, Vladimir I. Vladimirov

Psychology Publications

Alcohol consumption is known to lead to gene expression changes in the brain. After performing weighted gene co-expression network analyses (WGCNA) on genome-wide mRNA and microRNA (miRNA) expression in Nucleus Accumbens (NAc) of subjects with alcohol dependence (AD; N = 18) and of matched controls (N = 18), six mRNA and three miRNA modules significantly correlated with AD were identified (Bonferoni-adj. p≤ 0.05). Cell-type-specific transcriptome analyses revealed two of the mRNA modules to be enriched for neuronal specific marker genes and downregulated in AD, whereas the remaining four mRNA modules were enriched for astrocyte and microglial specific marker genes and …

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A Disproportionate Burden Of Care: Gender Differences In Mental Health, Health-Related Quality Of Life, And Social Support In Mexican Multiple Sclerosis Caregivers, Paul B. Perrin, Ivan Panyavin, Alejandra Morlett Paredes, Adriana Aguayo, Miguel Angel Macias, Brenda Rabago, Sandra J. Fulton Picot, Juan Carlos Arango-Lasprilla Jan 2015

A Disproportionate Burden Of Care: Gender Differences In Mental Health, Health-Related Quality Of Life, And Social Support In Mexican Multiple Sclerosis Caregivers, Paul B. Perrin, Ivan Panyavin, Alejandra Morlett Paredes, Adriana Aguayo, Miguel Angel Macias, Brenda Rabago, Sandra J. Fulton Picot, Juan Carlos Arango-Lasprilla

Psychology Publications

Background. Multiple sclerosis (MS) rates in Latin America are increasing, and caregivers there experience reduced mental and physical health. Based on rigid gender roles in Latin America, women more often assume caregiving duties, yet the differential impact on women of these duties is unknown. Methods. This study examined gender differences in mental health (Patient Health Questionnaire-9, Satisfaction with Life Scale, Rosenberg Self-Esteem Scale, State-Trait Anxiety Inventory, and Zarit Burden Inventory), health-related quality of life (HRQOL; Short Form-36), and social support (Interpersonal Support Evaluation List-12) in 81 (66.7% women) Mexican MS caregivers. Results. As compared to men caregivers, women had lower …

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Giftedness As Property: Troubling Whiteness, Wealth, And Gifted Education In The Us, Katherine Cumings Mansfield Jan 2015

Giftedness As Property: Troubling Whiteness, Wealth, And Gifted Education In The Us, Katherine Cumings Mansfield

Educational Leadership Publications

The purposes of this article are to illumine the racist genealogy of gifted education policies and practices in the United States, to demonstrate how deficit discourses continue today, and to provide personal examples from the field of how educators can begin to question the status quo, resist taken-for-granted assumptions, and alternatively make substantive changes at the local level. I also aim to demonstrate how giftedness is an example of whiteness as property, or unearned white privilege, that, unintentionally or not, maintains a social caste system in schools

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Using Natural Language Processing Techniques To Inform Research On Nanotechnology, Nastassja A. Lewinski, Bridget T. Mcinnes Jan 2015

Using Natural Language Processing Techniques To Inform Research On Nanotechnology, Nastassja A. Lewinski, Bridget T. Mcinnes

Chemical and Life Science Engineering Publications

Literature in the field of nanotechnology is exponentially increasing with more and more engineered nanomaterials being created, characterized, and tested for performance and safety. With the deluge of published data, there is a need for natural language processing approaches to semi-automate the cataloguing of engineered nanomaterials and their associated physico-chemical properties, performance, exposure scenarios, and biological effects. In this paper, we review the different informatics methods that have been applied to patent mining, nanomaterial/device characterization, nanomedicine, and environmental risk assessment. Nine natural language processing (NLP)-based tools were identified: NanoPort, NanoMapper, TechPerceptor, a Text Mining Framework, a Nanodevice Analyzer, a Clinical …

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Information Systems Strategy And The Role Of Chief Information Officers: Strategizing And Aligning Practices, Anna Karpovsky Jan 2015

Information Systems Strategy And The Role Of Chief Information Officers: Strategizing And Aligning Practices, Anna Karpovsky

2015

Information Systems (IS) pose both a challenge and an opportunity for organizations. The topic of strategizing around IS issues is thus of considerable importance. While there has been substantial academic research relating to the strategic value of IS – over 50 years – much of it focuses on such aspects of the topic as strategic IS planning, strategic alignment, and IS for competitive advantage. Fewer studies have taken into account the emergent nature of strategy formation. Fewer still have given attention to strategy-making practitioners, in particular their role and influence in the strategizing process. Accordingly, the goal of this dissertation …

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The Evolution Of Financial Instruments And The Legal Protection Against Counterfeiting: A Look At Coin, Paper, And Virtual Currencies, Ralph E. Mckinney, Lawrence P. Shao, Dale H. Shao, Duane C. Rosenblieb Jr. Jan 2015

The Evolution Of Financial Instruments And The Legal Protection Against Counterfeiting: A Look At Coin, Paper, And Virtual Currencies, Ralph E. Mckinney, Lawrence P. Shao, Dale H. Shao, Duane C. Rosenblieb Jr.

Management Faculty Research

This essay discusses the requirements for the long-term acceptance of virtual currency as a financial medium of exchange by examination of fundamental criteria associated with the historical development of common tender and selected virtual currencies. The relatively recent appearance of Internet-based transactions have necessitated developing virtual forms of payment such as virtual currencies. According to the Financial Crimes Enforcement Network (“FinCEN”) of the United States Treasury,5 virtual currencies are subject to regulation if that virtual currency has a substitutive purpose for facilitating the exchange of goods and services. Although governments can place stipulations on currencies, users of common tender, including …

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A Future For The Discipline Of Communication: Higher Education And Its Generational Transformations, James W. Chesebro, Christopher A. Flook Jan 2015

A Future For The Discipline Of Communication: Higher Education And Its Generational Transformations, James W. Chesebro, Christopher A. Flook

Iowa Journal of Communication

This critical essay traces the evolutions of and changes in higher education as a context for discussing the future of the discipline of communication. Some of the strengths and limitations of the 1975-2010 era, identified by Geiger (1995/2011) as the "Privatization and Current Era" in higher education, are detailed with special attention given to the increasing, if not unique, support of corporate organizations in funding and defining the agenda of higher education research during this era. This analysis functions as context for isolating teaching as a key component of the future of undergraduate communication higher education in the 2011-2036 era.

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Solutions To The Conflict In Kashmir, Nikolis Kurr Jan 2015

Solutions To The Conflict In Kashmir, Nikolis Kurr

International ResearchScape Journal

This policy paper investigates the conflict between India and Pakistan over the region of Kashmir in order to weigh whether a political rather than military resolution can be found. Various proposals to resolve the conflict are examined and evaluated. On the one hand, the possibility of Kashmir’s autonomy is considered; on the other, the solution of joint governance or, as a third option, formal partition of Kashmir in an Indian and Pakistani territory are explored. The importance of resuming political talks between India and Pakistan represents a primary first goal in order to make any resolution possible.

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For Patients And Profits: Ethical Astuteness And The Business Of Dialysis, Joshua E. Perry Jan 2015

For Patients And Profits: Ethical Astuteness And The Business Of Dialysis, Joshua E. Perry

Belmont Law Review

The view of ethical astuteness introduced and outlined in this paper aims to add value for a firm in the healthcare business – with a particular application to a for-profit organization providing dialysis services – by addressing two chief concerns: A.) The competing priorities between the patient’s interest in the healthcare encounter and the investor’s interest in generating a return on profits; and B.) The vulnerabilities of a financially-conflicted, for-profit healthcare provider to an allegation of medical malpractice.

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The Great Tactician: The Chief Justice, Obamacare, And Walking The Tightrope Of Partisan Politics, Katherine H. Blankenship Jan 2015

The Great Tactician: The Chief Justice, Obamacare, And Walking The Tightrope Of Partisan Politics, Katherine H. Blankenship

Belmont Law Review

This note argues that true judicial restraint is a fictional impossibility. Any practice of judicial restraint is at the very same moment an exercise of judicial activism because a judge cannot approach the law from a truly objective, mechanical position. Every judicial opinion is influenced not only by the political and moral vantage point of the judge, but also the judge’s policy and societal concerns. This thesis is illustrated by a case study of National Federation of Independent Business v. Sebelius, and, specifically, Chief Justice Roberts’s opinion regarding the individual mandate and the Medicaid provision of the Affordable Care Act. …

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Our Patient System And Health Care Information Technology: Valuable Incentive Or Impediment To Innovation?, Gary Montle, Ryan Levy, Margaret Rowland Jan 2015

Our Patient System And Health Care Information Technology: Valuable Incentive Or Impediment To Innovation?, Gary Montle, Ryan Levy, Margaret Rowland

Belmont Law Review

Patentable inventions have often been transformative, but the pace of such innovation has changed exponentially in the last thirty years. The patent law still seeks to reward ingenuity and nowhere should this maxim be truer than in the area of health information technology. But the pace and scope of changes in that arena have made rewarding that ingenuity with a patent increasingly difficult. The courts have struggled to apply patent laws to technology that is new and novel to a fault. This Article seeks to address how it is possible to continue to reward ingenuity in a field where progress …

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Gestational Surrogacy Contracts In Tennessee: Freedom Of Contract Concerns & Feminist Principles In The Balance, Jennifer S. White Jan 2015

Gestational Surrogacy Contracts In Tennessee: Freedom Of Contract Concerns & Feminist Principles In The Balance, Jennifer S. White

Belmont Law Review

Drawing upon feminist theory and principles of freedom of contract, this Note proposes a new statutory framework for addressing surrogacy in the state of Tennessee. Part I provides a balanced discussion of why couples choose surrogacy as well as varying types of surrogacy available to individuals. Part II explores the judicial and legislative responses toward surrogacy contracts in the United States and discusses significant surrogacy litigation that continues to shape the public policy arguments surrounding this issue. Part III provides background on Tennessee’s approach to the right to privacy as well as recent surrogacy case law and legislation. Part IV …

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The Intervention Of Active Learning Strategies To Increase Nursing Student Self-Directed Learning, Janelle A. Patterson Jan 2015

The Intervention Of Active Learning Strategies To Increase Nursing Student Self-Directed Learning, Janelle A. Patterson

Regis University Student Publications (comprehensive collection)

Executive Summary

Problem
Undergraduate nursing students at a Midwestern community college struggled to understand and retain content presented in long lecture format courses. The Population, Intervention, Comparison, and Outcomes (PICO) for the program are as follows: P—Nursing students at a Midwestern community college in terms 1, 2, 4, and 5 of the LPN and ADN program; I—Use of guided practice as an active learning teaching strategy in the lab setting to enhance nursing student self-directed learning readiness in terms 1 and 4; C— Nursing students in term 2 and term 5 at a Midwestern community college who did not have …

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Evaluating Development Of Critical Thinking Skills In Simulation Learning, Cynthia J. Helgesen Jan 2015

Evaluating Development Of Critical Thinking Skills In Simulation Learning, Cynthia J. Helgesen

Regis University Student Publications (comprehensive collection)

Executive Summary
Evaluating Development of Critical Thinking Skills in Simulation Learning Problem
Critical thinking is the key to nurses' ability to make sound decisions in clinical practice. It was determined nurses, hired within the last three years at an Intermediate Care Facility for the Mentally Retarded (ICFMR), required additional education and practice to manage high-risk low frequency events, specifically respiratory emergencies. Project questions for this quality improvement initiative included: Will a high fidelity simulation session improve critical thinking skills for registered nurses hired within the last three years, at the ICFMR? And, will the introduction of simulation learning to develop …

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Bowling Green Civil War Round Table Newsletter (Jan. 2015), Manuscripts & Folklife Archives Jan 2015

Bowling Green Civil War Round Table Newsletter (Jan. 2015), Manuscripts & Folklife Archives

Bowling Green Civil War Round Table Newsletter

No abstract provided.

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Bowling Green Civil War Round Table Newsletter (Feb. 2015), Manuscripts & Folklife Archives Jan 2015

Bowling Green Civil War Round Table Newsletter (Feb. 2015), Manuscripts & Folklife Archives

Bowling Green Civil War Round Table Newsletter

No abstract provided.

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No Caste Here? Toward A Structural Critique Of American Education, Daniel Kiel Jan 2015

No Caste Here? Toward A Structural Critique Of American Education, Daniel Kiel

Dickinson Law Review (1908-2003)

In his famous dissent in Plessy v. Ferguson, Justice John Marshall Harlan argued that in the United States, there was "no caste here." Justice Harlan was rejecting the idea that American society operated to assign preordained outcomes to individuals based upon classifications, including racial classifications. This Article questions whether Justice Harlan's aspirational assertion accurately reflects contemporary American education. Identifying: (1) multiple classification mechanisms, all of which have disproportionate racial effects, and (2) structural legal, political, and practical impediments to reform, the Article argues that the American education system does more to maintain the nation's historical racial hierarchy than to disrupt …

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International Criminal Law, Gail A. Partin Jan 2015

International Criminal Law, Gail A. Partin

Faculty Contributions to Books

The Electronic Resource Guide, often called the ERG, has been published online by ASIL since 1997. Systematically updated and continuously expanded, the ERG is designed to be used by students, teachers, practitioners, and researchers as a self-guided tour of relevant, quality, up-to-date online resources covering important areas of international law. The ERG also serves as a ready-made teaching tool at graduate and undergraduate levels.

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The Asymmetrical Bridge: A Review Of James Tabery's Book "Beyond Versus.", David S. Moore Jan 2015

The Asymmetrical Bridge: A Review Of James Tabery's Book "Beyond Versus.", David S. Moore

Pitzer Faculty Publications and Research

No abstract provided.

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Permutation Invariant Lattices, Lenny Fukshansky, Stephan Ramon Garcia, Xun Sun Jan 2015

Permutation Invariant Lattices, Lenny Fukshansky, Stephan Ramon Garcia, Xun Sun

CMC Faculty Publications and Research

We say that a Euclidean lattice in Rn is permutation invariant if its automorphism group has non-trivial intersection with the symmetric group Sn, i.e., if the lattice is closed under the action of some non-identity elements of Sn. Given a fixed element τ ∈ Sn, we study properties of the set of all lattices closed under the action of τ: we call such lattices τ-invariant. These lattices naturally generalize cyclic lattices introduced by Micciancio in [8, 9], which we previously studied in [1]. Continuing our investigation, we discuss some basic properties of permutation invariant lattices, in particular proving that the …

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The End Of The Natural Law: Dietrich Bonhoeffer's Christological Ethics., Jordan J. Ballor Jan 2015

The End Of The Natural Law: Dietrich Bonhoeffer's Christological Ethics., Jordan J. Ballor

CTS PhD Doctoral Dissertations

Dietrich Bonhoeffer (1906-1945) has often been understood as articulating an occasionalistic, divine-command theory of ethics. In this regard, he is often seen as aligned with Karl Barth (1886-1968). This study challenges this view by demonstrating that Bonhoeffer’s own ethical project was aimed at resuscitating and reviving a distinctively Protestant form of natural-law thinking. Bonhoeffer’s approach was characterized by an emphasis on the origin, formation, and goal of natural mandates in, by, and toward Jesus Christ. Bonhoeffer’s early teaching concerning orders of preservation and laws of life was developed into a mature doctrine of divine mandates in his Ethics, which are …

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The Importance Of Agency Design For Successful Competition Policy In Broadband, Maureen K. Ohlhausen Jan 2015

The Importance Of Agency Design For Successful Competition Policy In Broadband, Maureen K. Ohlhausen

Colorado Technology Law Journal

No abstract provided.

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A Narrative Inquiry Into The Experiences Of Evangelical Christians Leading In Public Schools During Culture War Skirmishes, Gary F. Sehorn Jan 2015

A Narrative Inquiry Into The Experiences Of Evangelical Christians Leading In Public Schools During Culture War Skirmishes, Gary F. Sehorn

All Electronic Theses and Dissertations

The intent of this exploratory, descriptive narrative inquiry was to understand the experiences of selected evangelicals serving as public school administrators who lead in the midst of skirmishes involving evangelical Christians and the local public schools where they serve. These conflicts are part of the larger cultural conflict between evangelical Christianity and public education. The narratives of five leaders were captured through semi-structured, in-depth interviews. The purposeful sample of participants included administrators from Texas, Southern California, and the South, the Midwest, and the Pacific Northwest. Each participant shared a skirmish story and its cultural and geographic context. In the process, …

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“If You’Re Not Having Fun, What’S The Point Of Playing?” Adolescents’ Best And Worst Interscholastic Sport Experiences, Troy D. Urdahl Jan 2015

“If You’Re Not Having Fun, What’S The Point Of Playing?” Adolescents’ Best And Worst Interscholastic Sport Experiences, Troy D. Urdahl

All Electronic Theses and Dissertations

Interscholastic athletics are purported to provide many benefits for participants. Some studies have shown the benefits of playing sports, but others have cautioned the expense is not worth the investment and not all outcomes of participation are positive. High school athletics are deeply woven into the American educational system, yet limited research has been conducted to capture the voices of student-athletes to identify their perceptions of sport experiences. Learning this information may help various stakeholders improve interscholastic sport experiences. Therefore, the purpose of this existential-phenomenological study was to examine the best and worst sports experiences of interscholastic athletes in team …

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The Fourth Amendment And Bulk Telephone Metadata: An Overview Of Recent Case Law, Steven G. Stransky Jan 2015

The Fourth Amendment And Bulk Telephone Metadata: An Overview Of Recent Case Law, Steven G. Stransky

Saint Louis University Public Law Review

No abstract provided.

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Judicialization Of Political Conflict: Evidence Of Brown V. Board Of Education’S Effect In Newspaper Opinion, Neal Allen Jan 2015

Judicialization Of Political Conflict: Evidence Of Brown V. Board Of Education’S Effect In Newspaper Opinion, Neal Allen

Saint Louis University Public Law Review

No abstract provided.

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High Value Lies, Ugly Truths, And The First Amendment, Alan K. Chen, Justin F. Marceau Jan 2015

High Value Lies, Ugly Truths, And The First Amendment, Alan K. Chen, Justin F. Marceau

Sturm College of Law: Faculty Scholarship

Lying has a complicated relationship with the First Amendment. It is beyond question that some lies – such as perjury or pretending to be a police officer – are not covered by the First Amendment. But it is equally clear that some lies, even intentionally lying about military honors, are entitled to First Amendment protection. U.S. v. Alvarez, 132 S. Ct. 2537 (2012). To date, however, both Supreme Court doctrine and academic commentary has taken for granted that any constitutional protection for lies is purely prophylactic – it protects the liar to avoid chilling truthful speech. This Article is the …

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Public Lawyers And Marijuana Regulation, Sam Kamin, Eli Wald Jan 2015

Public Lawyers And Marijuana Regulation, Sam Kamin, Eli Wald

Sturm College of Law: Faculty Scholarship

Although 23 states and the District of Columbia have now legalized marijuana for medical purposes, marijuana remains a prohibited substance under federal law. Because the production, sale, possession and use of marijuana remain illegal, there is a risk of prosecution under federal laws. Furthermore, those who help marijuana users and providers put themselves at risk — federal law punishes not only those who violate drug laws but also those who assist or conspire with them to do so. In the case of lawyers representing marijuana users and businesspeople, this means not only the real (though remote) risk of criminal prosecution …

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