Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 31021 - 31050 of 1192942

Full-Text Articles in Entire DC Network

Msw Portfolio, Jennifer Lynn Barnhill Aug 2025

Msw Portfolio, Jennifer Lynn Barnhill

Graduate Student Portfolios, Professional Papers, and Capstone Projects

The Master of Social Work (MSW) Portfolio is a sample of the essays, presentations, projects, and experiences completed as part of my online MSW curriculum at the University of Montana (UM) School of Social Work (SSW) from 2022-2025. Throughout this narrative, I’ll describe the skills, values, theories, and frameworks I’ve learned during my three years working toward my master's degree in social work. Each of the appendices will demonstrate an understanding of the nine Council on Social Work Education, or CSWE, competencies (Texas College, n.d.) that all social workers are expected to meet, along with a tenth competency added by …


Msw Portfolio 2025, Lacie R. Ranieri Aug 2025

Msw Portfolio 2025, Lacie R. Ranieri

Graduate Student Portfolios, Professional Papers, and Capstone Projects

MSW Portfolio - 2025


Synthesis, Biological Activity And Molecular Docking Study Of Some New Chalcones, 5,6-Dihydropyrimidin-2-Ol And 5,6-Dihydropyrimidin-2-Thiol Derivatives Bearing 1,2,3- Triazoline, Hayder Raheem Ali, Ahmed Wahed Naser Aug 2025

Synthesis, Biological Activity And Molecular Docking Study Of Some New Chalcones, 5,6-Dihydropyrimidin-2-Ol And 5,6-Dihydropyrimidin-2-Thiol Derivatives Bearing 1,2,3- Triazoline, Hayder Raheem Ali, Ahmed Wahed Naser

Baghdad Science Journal

Many new chemicals, including chalcones, derivatives of 5,6-dihydropyrimidin-2-ol and 5,6-dihydropyrimidin-2-thiol, are synthesized in this work. The starting materials are substituted acetophenone derivatives involving 1,2,3-triazoline (1). Chalcone derivatives (2a-h) were obtained by condensing compound (1) with some substituted aromatic aldehydes in the presence of 40% potassium hydroxide KOH. The process of producing pyrimidin-2-ol derivatives (3a–e) by cyclizing produced chalcone derivatives (2a–e) urea in the presence of sodium hydroxide. Equivalent pyrimidin-2-thiol derivatives (4a-d) were produced when chalcone derivatives (2a-d) reacted with thiourea in the presence of sodium hydroxide. The …


Chromatographic Developments For The Analysis Of Toxic Organic Chemicals In The Environment And Food Samples, Stephanie Devi Nauth Aug 2025

Chromatographic Developments For The Analysis Of Toxic Organic Chemicals In The Environment And Food Samples, Stephanie Devi Nauth

Graduate Thesis and Dissertation post-2024

As awareness grows about compounds harmful to human health, the need for sensitive detection methods at low concentration levels becomes increasingly critical. Chromatography is a powerful analytical technique that enables the separation of complex mixtures, allowing for the simultaneous analysis of multiple analytes—even at trace levels. This dissertation applies chromatography in two distinct contexts: (1) Investigating the sorption of polycyclic aromatic sulfur heterocycles (PASHs) onto nylon microplastics; and (2) Detecting illegal dyes in various food matrices.

Microplastics have emerged as significant vectors for transporting pollutants into aquatic ecosystems. Due to their hydrophobic nature, many organic pollutants readily sorb onto microplastics …


Pride Or Prejudice: An Examination Of Queer Content In Florida High Schools, Niamh L. Harrop Aug 2025

Pride Or Prejudice: An Examination Of Queer Content In Florida High Schools, Niamh L. Harrop

Graduate Thesis and Dissertation post-2024

This thesis explores how queer individuals reflect on the presence—or more often, the absence—of queer content in their high school education. Despite increasing visibility of LGBTQ+ people in popular culture and legal reform, formal educational spaces remain largely heteronormative and cisnormative structured from a heterosexual and cisgender standpoint. Through a critical qualitative approach, this study draws on semi-structured interviews with 13 queer participants who attended high school in Florida in the years between the legalization of same-sex marriage in 2015 and the passage of Florida’s H.B. 1557 (“Don’t Say Gay” law) in 2022. Using thematic analysis, four key themes were …


Effectiveness Of Leadership Rounding In Reducing Patient-Related Falls In A Medical-Surgical Unit, Elsie-Solange Mvoueng Nkoi-Mimba Aug 2025

Effectiveness Of Leadership Rounding In Reducing Patient-Related Falls In A Medical-Surgical Unit, Elsie-Solange Mvoueng Nkoi-Mimba

Walden Dissertations and Doctoral Studies

Summary In this Doctor of Nursing Practice (DNP) project, I evaluated whether the project site organization’s implementation of leadership rounding reduced patient falls within a medical-surgical unit. Despite established fall prevention strategies, the unit continued to experience ongoing incidents, prompting the implementation of structured leadership rounding. The practice-focused question assessed changes in fall rates over a 3-month postintervention period compared to the preceding 3 months. A retrospective chart review was conducted from December 2023 to June 2024, excluding March 2024 due to partial implementation. I used descriptive statistics to analyze trends. The average monthly fall rate remained stable at 2.67 …


What Are The Predictors Of Malignancy In Inflammatory Bowel Disease?, Zülal İstemi̇han, Bi̇lger Çavuş, Ali̇ Emre Bardak, Ayşe Merve Kirkoğlu, Cansu Kiziltaş, Rüveyda Si̇lay, İbrahi̇m Volkan Şenkal, Zi̇ya İmanov, Kenan Nuri̇yev, Aynure Rüstemzade, Sezen Genç, Mi̇ne Güllüoğlu, Asli Çi̇fci̇başi Örmeci̇, Kadi̇r Demi̇r, Fati̇h Beşişik, Sabahatti̇n Kaymakoğlu, Fi̇li̇z Akyüz Aug 2025

What Are The Predictors Of Malignancy In Inflammatory Bowel Disease?, Zülal İstemi̇han, Bi̇lger Çavuş, Ali̇ Emre Bardak, Ayşe Merve Kirkoğlu, Cansu Kiziltaş, Rüveyda Si̇lay, İbrahi̇m Volkan Şenkal, Zi̇ya İmanov, Kenan Nuri̇yev, Aynure Rüstemzade, Sezen Genç, Mi̇ne Güllüoğlu, Asli Çi̇fci̇başi Örmeci̇, Kadi̇r Demi̇r, Fati̇h Beşişik, Sabahatti̇n Kaymakoğlu, Fi̇li̇z Akyüz

Turkish Journal of Medical Sciences

Background/aimː This study aims to investigate the prevalence of malignancy in patients with inflammatory bowel disease (IBD) followed up in a tertiary reference center.

Materials and methodsː IBD patients with at least 6 months of follow-up from the gastroenterology clinic between 2000 and 2022 wereevaluated retrospectively in a tertiary center. Patient information was obtained from the patient registration system.

Resultsː There were 697 patients in the study, 320 (45.9%) of these were female. The mean age of the patients at IBD diagnosis was 33.4± 13.1 years. The mean follow-up time was 93.1 ± 64.8 (median 84, IQR (25–75) (36–144)) months. …


Blood Group Profile Of Türkiye With Regional And Demographic Differences: A 23-Year Retrospective Study, Levent Sağdur, Azi̇z Karaca, Mustafa Nuri̇ Günçikan, Mustafa Yilmaz, Kerem Kinik Aug 2025

Blood Group Profile Of Türkiye With Regional And Demographic Differences: A 23-Year Retrospective Study, Levent Sağdur, Azi̇z Karaca, Mustafa Nuri̇ Günçikan, Mustafa Yilmaz, Kerem Kinik

Turkish Journal of Medical Sciences

Background/aim: This study aims to comprehensively analyze the distribution of ABO and Rh blood groups, as well as demographic characteristics and regional variations, using data from 9.5 million blood donors across Türkiye.

Materials and methods: In this multicenter, retrospective, cross-sectional study, data were collected from 9,587,592 healthy, voluntary donors who donated to the Turkish Red Crescent between 1998 and 2021. Donors met the criteria of being 18–70 years old, weighing over 50 kg, with hemoglobin levels above 13.5 g/dL for male and 12.5 g/dL for female. The data were evaluated based on age, gender, education level, and geographic region.

Results: …


Evaluation Of Teachers' Knowledge And Awareness About Autism Spectrum Disorder, Hami̇t Harun Bağci, Abi̇de Aksungur, Gülsüm Öztürk Emi̇ral, Erhan Şi̇mşek Aug 2025

Evaluation Of Teachers' Knowledge And Awareness About Autism Spectrum Disorder, Hami̇t Harun Bağci, Abi̇de Aksungur, Gülsüm Öztürk Emi̇ral, Erhan Şi̇mşek

Turkish Journal of Medical Sciences

Background/aim: Teachers play an essential role in the early identification of autism spectrum disorder (ASD) and associated difficulties in children. Increasing teachers’ knowledge of ASD can be helpful in identifying these children and making the necessary referrals. This study aimed to assess teachers’ knowledge and awareness of ASD and the factors affecting them.

Materials and methods: This is a cross-sectional study conducted among school counsellors. A total of 171 school counsellors were contacted; school visits were arranged by prior appointment, and the purpose of the study was explained. Data were collected using a questionnaire prepared by the researchers and the …


Evaluating Current Practices In Operative Nontechnical Skills Training And Feedback In General Surgery Residency: A Mixed Methods Approach, Madeline Cloonan Aug 2025

Evaluating Current Practices In Operative Nontechnical Skills Training And Feedback In General Surgery Residency: A Mixed Methods Approach, Madeline Cloonan

Theses & Dissertations

Background: Non-technical skills (NTS) are the interpersonal and cognitive abilities that are critical to accomplishing high-risk tasks. Deficiencies in NTS, including communication, teamwork, leadership, and decision-making, are linked to errors in the operating room. Structured training and feedback in NTS remain inconsistent and have not been integrated into daily training. This dissertation addresses this gap by evaluating current NTS training and feedback practices and developing a rubric to enhance the effectiveness of NTS feedback.

Methods: We conducted five complementary studies to assess current NTS training and feedback. The first was a systematic review aimed at identifying intraoperative NTS training interventions …


Error Processing In Psychopathy: An Analysis Of Event Related Brain Potentials And Post-Error Task Behavior, Ananda Liz Peixoto Couto Aug 2025

Error Processing In Psychopathy: An Analysis Of Event Related Brain Potentials And Post-Error Task Behavior, Ananda Liz Peixoto Couto

UNLV Theses, Dissertations, Professional Papers, and Capstones

Performance monitoring and error processing are crucial for learning from mistakes, adjusting responses, and adapting to the environment. Individuals with psychopathy present with failures in performance monitoring, particularly a failure to learn from experience, and error processing deficits have been reported in this population. Error processing literature has investigated its underlying mechanisms via two prongs, namely behavioral measures and electroencephalography (EEG) indicators. Behaviorally, error processing literature has focused on post-error slowing (PES) and post-error accuracy (PEA). Meanwhile, EEG research has identified two components of error-related brain potentials (ERPs) in error processing: error-related negativity (ERN) and error positivity (Pe). This study …


Butte Priority Soils Operable Unit (Bpsou) Revised Butte Hill Revegetation Specifications, Mike Mcanulty, Eric Hassler Aug 2025

Butte Priority Soils Operable Unit (Bpsou) Revised Butte Hill Revegetation Specifications, Mike Mcanulty, Eric Hassler

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


An Examination Of The Purity Culture Beliefs Scale And The Interaction Of Religiosity, Purity Culture Beliefs, And Pornography Use In A Census-Matched United States Sample, Kaelyn R. Griffin Aug 2025

An Examination Of The Purity Culture Beliefs Scale And The Interaction Of Religiosity, Purity Culture Beliefs, And Pornography Use In A Census-Matched United States Sample, Kaelyn R. Griffin

UNLV Theses, Dissertations, Professional Papers, and Capstones

The impacts of purity culture have been documented in the prevalence of abstinence-only sex education, perception of personal value tied to virginity, and shame and guilt related to sexual behavior. Similarly, models of moral incongruence often examine religiosity as a contributor of distress related to sexual behavior and pornography use, likely tapping into the influence of purity culture without directly naming its presence. This distinction is crucial due to the variety of religious beliefs and practices, some including purity culture and those without sexually restrictive beliefs and practices. Despite this, standardized measures for researching purity culture are limited. Ortiz (2018) …


Assessing The Impact Of Cdbg And Home Block Grants On Housing Affordability In The Las Vegas–Henderson–Paradise Metropolitan Statistical Area, David Hasan Aug 2025

Assessing The Impact Of Cdbg And Home Block Grants On Housing Affordability In The Las Vegas–Henderson–Paradise Metropolitan Statistical Area, David Hasan

UNLV Theses, Dissertations, Professional Papers, and Capstones

This dissertation aimed to analyze the impacts of aggregated federal funding from the CDBG and HOME block grants on temporal changes in the Housing Affordability Index (HAI Change). The temporal change in Housing Affordability between 2011–2015 and 2016–2020 was constructed as the dependent variable to measure the direct and indirect impacts of CDBG/HOME funding. Therefore, this dissertation seeks to identify the impacts of aggregated funding on changes in housing affordability and to explore spatial spillover effects through spatial dependencies that may influence housing affordability change as a dependent variable. The geographical area of this study is the Las Vegas–Henderson–Paradise MSA, …


Empowering Science With The World's First High Accuracy And High Throughput Functional Assay, Christopher Giacoletto Aug 2025

Empowering Science With The World's First High Accuracy And High Throughput Functional Assay, Christopher Giacoletto

UNLV Theses, Dissertations, Professional Papers, and Capstones

Understanding the functional consequences of genetic mutations remains a central challenge in modern biology, with far-reaching implications for human health and disease. While early systematic methods like alanine scanning and phage display provided foundational insights into protein structure and function, the emergence of high-throughput approaches—such as Multiplexed Assays of Variant Effect (MAVEs)—and predictive tools powered by artificial intelligence have vastly expanded our ability to profile mutational landscapes. However, these methods are often constrained by trade-offs between accuracy, scalability, and biological relevance.This dissertation presents the development and application of the GigaAssay, the world’s first high-throughput functional assay capable of delivering both …


Investigating Information Extraction And Language Models In Medical Domain Text Processing, Pouyan Nahed Aug 2025

Investigating Information Extraction And Language Models In Medical Domain Text Processing, Pouyan Nahed

UNLV Theses, Dissertations, Professional Papers, and Capstones

This dissertation demonstrates that carefully adapted language-model pipelines can transform unstructured clinical-trial and pharmacological prose into reliable, low-latency structured data. Four interconnected studies support this claim.Tri-AL platform. An open-source dashboard ingests all 440 k+ ClinicalTrials.gov records—including every historical revision—into a normalized schema and parses the 20 GB XML archive over 10x faster than a BeautifulSoup baseline, while exposing hooks for demographic analytics and supporting integration of user-defined modules. Clinical trial summarization. An encoder–decoder model is trained on 57k description–summary pairs to condense clinical trials into a few sentences. ROUGE evaluation shows a 20% improvement over the baseline, while graph-based evaluation …


Identifying Appropriate Clinical Cutoffs For Traumatic Dissociation In Maltreated Youth, Amanda L. Mraz Aug 2025

Identifying Appropriate Clinical Cutoffs For Traumatic Dissociation In Maltreated Youth, Amanda L. Mraz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Maltreated youth who experience traumatic dissociation are at an increased risk for various severe psychopathological outcomes. Much is still unknown about the risk factors for traumatic dissociation in maltreated youth. The present study aimed to identify dissociation (e.g., dissociative amnesia, absorption and imaginative involvement, passive influence, and depersonalization and derealization) risk factors, via parametric statistical methods, in association with the appropriate clinical cutoff for the total and subscale scores from the Adolescent Dissociative Experiences Scale (A-DES). Investigatory variables included demographic (e.g., age, race, and gender), cognitive (e.g., resiliency and posttraumatic cognitions), and psychological (e.g., posttraumatic stress disorder, anxiety, and depression …


Understanding The Role Of Drug Offenses And The Death Penalty In Iran, Cyrus Zarganj Aug 2025

Understanding The Role Of Drug Offenses And The Death Penalty In Iran, Cyrus Zarganj

UNLV Theses, Dissertations, Professional Papers, and Capstones

Since the 1979 revolution, the Islamic Republic of Iran has been governed by Islamic laws devised by Shia Muslim clerics, significantly influencing the nation's legal framework in both criminal and civil contexts. The death penalty in Iran covers a broad spectrum of offenses, many of which would not be considered capital crimes or even crimes globally. This extensive application of the death penalty is an instrument of social control during periods of political tension, indicating a direct relationship between the regime's stability and the enforcement of extreme punitive measures. Despite some reduction in the visibility of executions due to international …


Ability Of Staphylococcus Epidermidis And Escherichia Coli To Eliminate Cadmium, Lead And Copper From Tigris River In Mosul City, May A. Abdul Kader, Ghada A. Mohammad Aug 2025

Ability Of Staphylococcus Epidermidis And Escherichia Coli To Eliminate Cadmium, Lead And Copper From Tigris River In Mosul City, May A. Abdul Kader, Ghada A. Mohammad

Baghdad Science Journal

The heavy metals are non-biodegradable and could be toxic and carcinogenic, thus, their improper concentration in water could result in critical health issues for living organisms. Therefore, this study aimed to remove three heavy metals (Cadmium, lead and copper) by biological treatment especially using environmental nonpathogenic bacteria such as Staphylococcus epidermidis and Escherichia coli. Eight samples were collected from Tigris River from different regions of Mosul city. Two containers were used for each sample to measure the concentration of minerals before and after treatment by bacteria. The results showed that E. coli was more efficient in removing two heavy …


The Experience Of Posttraumatic Growth For Atheists, Savannah Miller Aug 2025

The Experience Of Posttraumatic Growth For Atheists, Savannah Miller

Doctoral Dissertations

Background - This study aimed to understand how atheists manage to make meaning and find growth after experiencing trauma. Posttraumatic Growth is a well documented point of research across qualitative and quantitative domains, and this project aimed to add meaningful findings to that research body. Atheists, however, are an understudied population, especially as it relates to their subjective experience of trauma and posttraumatic growth.

Methods - This study aimed to investigate the experience of posttraumatic growth for atheistindividuals. Semi-structured interviews adhering to the tenets of interpretive phenomenological analysis were conducted then transcribed, coded, and analyzed. Themes and subthemes emerged and …


Analyzing Food Access: An Investigation Of Food Insecurity Amongst Latinos In Rural Nebraska, Natalia Santos Aug 2025

Analyzing Food Access: An Investigation Of Food Insecurity Amongst Latinos In Rural Nebraska, Natalia Santos

Theses & Dissertations

Background: Food insecurity is a public health issue in the United States, with disproportionately higher rates among Latino/Hispanic households. Rural communities face unique geographical, socioeconomic, and systemic barriers that often exacerbate food access disparities. Despite the growing Latino population in rural areas, particularly in Midwestern states like Nebraska, there remains a critical gap in comprehensive research that integrates both objective and subjective understandings of their food environments. Understanding these multifaceted influences is crucial for developing effective, culturally sensitive interventions.

Problem Statement: This dissertation aims to answer the central question: How does food access and food insecurity manifest amongst Latinos in …


Diverse Cell Types Establish A Pathogenic Immune Environment In Peripheral Neuropathy, Julie Choi Aug 2025

Diverse Cell Types Establish A Pathogenic Immune Environment In Peripheral Neuropathy, Julie Choi

Arts & Sciences Graduate Student Theses and Dissertations

Neuroinflammation plays a complex and context-dependent role in many neurodegenerative diseases. We identified a key pathogenic function of macrophages in a mouse model of a rare human congenital neuropathy in which SARM1, the central executioner of axon degeneration, is activated by hypomorphic mutations in the axon survival factor NMNAT2. Macrophage depletion blocked and reversed neuropathic phenotypes in this sarmopathy model, revealing SARM1-dependent neuroimmune mechanisms as key drivers of disease pathogenesis. In this study, we investigated the impact of chronic subacute SARM1 activation on the peripheral nerve milieu using single cell/nucleus RNA-sequencing (sc/snRNA-seq). Our analyses reveal an expansion of immune cells …


Emotions And Narrative In Sophocles' Fragmentary Tragedies "Tyro" (A’ And B’) And "Tereus", Maria Eugenia Bonaparte Gimenez Aug 2025

Emotions And Narrative In Sophocles' Fragmentary Tragedies "Tyro" (A’ And B’) And "Tereus", Maria Eugenia Bonaparte Gimenez

Arts & Sciences Graduate Student Theses and Dissertations

The purpose of this master’s thesis is to explore the possibility of gaining a better understanding of Sophocles’ fragmentary tragedies by taking emotions into consideration. I focus on three of those plays, Tereus, and Tyro A’ and B’, and put them in relation to the mythological narratives from which they derived, as well as other examples of reception. By considering the basic narrative patterns of the myth and their rendering in different media alongside emotional scripts, we can support or challenge existing hypotheses about these fragmentary plays. At the conclusion of this study, I demonstrate that emotions have …


Isolation And Divergence Of Greater Earless Lizards (Phrynosomatidae: Cophosaurus) In Western North America Support Multiple Diversification Processes And A Complex Demographic History, Christopher Robert Blair, Carlos Joaquín Pavón-Vázquez, Qaantah Rana, Keaka Farleigh, Erika Crispo, Thomas Panzera, Felipe De Medeiros Magalhães, Britt White, Uri Omar Garcia-Vazquez Aug 2025

Isolation And Divergence Of Greater Earless Lizards (Phrynosomatidae: Cophosaurus) In Western North America Support Multiple Diversification Processes And A Complex Demographic History, Christopher Robert Blair, Carlos Joaquín Pavón-Vázquez, Qaantah Rana, Keaka Farleigh, Erika Crispo, Thomas Panzera, Felipe De Medeiros Magalhães, Britt White, Uri Omar Garcia-Vazquez

Publications and Research

The Southwestern US and northern Mexico continue to serve as ideal regions to elucidate the suite of ecological and evolutionary processes influencing lineage diversification. The complex geological history of arid North America, coupled with paleoclimate change during the Pleistocene and diverse ecoregions makes a multipronged approach to hypothesis testing necessary. We combine thousands of loci from a genotyping-by-sequencing (GBS) approach along with mitochondrial DNA (mtDNA) sequences from the Greater Earless Lizard (Cophosaurus texanus) to examine diversity and test for cryptic population structure. We also apply recently developed coalescent approaches in a Bayesian framework to estimate migration rates. Population …


Outcomes Of Patients With Newly Diagnosed Acute Myeloid Leukemia With Flt3-Tyrosine Kinase Domain Mutations: Prognostic Implications Of Npm1 Co-Mutation, Sankalp Arora, Wei-Ying Jen, Musa Yilmaz, Indraneel Deshmukh, Jayastu Senapati, Sanam Loghavi, Ghayas C Issa, Nicholas J Short, Tapan M Kadia, Courtney D Dinardo, Gautam Borthakur, Joseph Jabbour, Naveen Pemmaraju, Michael Andreeff, Koichi Takahashi, Kapil Bhalla, Uday Popat, Elizabeth J Shpall, Betul Oran, Hussein A Abbas, Guillermo Garcia-Manero, Farhad Ravandi, Hagop Kantarjian, Naval Daver Aug 2025

Outcomes Of Patients With Newly Diagnosed Acute Myeloid Leukemia With Flt3-Tyrosine Kinase Domain Mutations: Prognostic Implications Of Npm1 Co-Mutation, Sankalp Arora, Wei-Ying Jen, Musa Yilmaz, Indraneel Deshmukh, Jayastu Senapati, Sanam Loghavi, Ghayas C Issa, Nicholas J Short, Tapan M Kadia, Courtney D Dinardo, Gautam Borthakur, Joseph Jabbour, Naveen Pemmaraju, Michael Andreeff, Koichi Takahashi, Kapil Bhalla, Uday Popat, Elizabeth J Shpall, Betul Oran, Hussein A Abbas, Guillermo Garcia-Manero, Farhad Ravandi, Hagop Kantarjian, Naval Daver

Faculty, Staff and Student Publications

Background: The prognostic impact of Fms-like tyrosine kinase 3 (FLT3)-tyrosine kinase domain (TKD) mutation in patients with acute myeloid leukemia (AML) is not well defined. The authors described outcomes of one of the largest cohorts of patients with FLT3-TKD mutated (FLT3-TKDmut) AML to date.

Methods: This retrospective study included patients with newly diagnosed AML who received frontline treatment at The University of Texas MD Anderson Cancer Center from January 2012 to March 2024 divided into two cohorts: FLT3-TKDmut AML and nucleophosmin-mutated (NPM1mut)/FLT3-TKD wild-type (FLT3-TKDwt) AML. Patients with FLT3 internal tandem duplication mutations were excluded.

Results: In total, 2922 patients were …


Anatomy Of An Ai Arms Race: U.S. And China Technological Dispute For Ai Leadership, Denisse I. Rojas Maldonado Aug 2025

Anatomy Of An Ai Arms Race: U.S. And China Technological Dispute For Ai Leadership, Denisse I. Rojas Maldonado

Dartmouth College Master’s Theses

The history of societies and the emergence of powerful states have been marked by cycles of conflict and war, followed by periods of cooperation that foster international stability. Similarly, the Cold War era saw a significant rise in military and economic capabilities, which highlighted a security dilemma as the former USSR and the United States sought to protect their national interests. Currently, artificial intelligence has expanded the scope of invisible warfare beyond the atomic bomb. Some scholars like Paul Scharre advocate that there is no arms race in place, and others support the idea of a healthy competition and collaboration …


Randomised, Placebo-Controlled Trial Of Oral Hymecromone In Adults With Pulmonary Hypertension, Kathryn Czepiel, Nadine Nagy, Tamera Panjalingam, Anissa Kalinowski, Adam R Frymoyer, Harry Karmouty-Quintana, Bo Gu, Haley Hedlin, Gernot Kaber, Sylvie Dobrota Lai, Joelle I Rosser, Paul L Bollyky, Vinicio De Jesus Perez, Roham T Zamanian Aug 2025

Randomised, Placebo-Controlled Trial Of Oral Hymecromone In Adults With Pulmonary Hypertension, Kathryn Czepiel, Nadine Nagy, Tamera Panjalingam, Anissa Kalinowski, Adam R Frymoyer, Harry Karmouty-Quintana, Bo Gu, Haley Hedlin, Gernot Kaber, Sylvie Dobrota Lai, Joelle I Rosser, Paul L Bollyky, Vinicio De Jesus Perez, Roham T Zamanian

Faculty, Staff and Student Publications

Background: Pulmonary hypertension (PH) is a progressive cardiopulmonary condition associated with increased morbidity and mortality. The extracellular matrix component hyaluronan (HA) is linked to vascular remodelling and interstitial fibrosis in PH. We hypothesised that inhibition of HA synthesis with hymecromone could serve as a reverse-remodelling therapy in PH.

Methods: We performed a proof-of-concept phase IIa randomised, double-blind, placebo-controlled study in adults with pulmonary arterial hypertension and PH associated with interstitial lung disease (PH-ILD). Patients were randomised to a 5:3 ratio and stratified by PH group to receive oral hymecromone or placebo two times per day over 24 weeks. The primary …


Education Outcomes From An Ophthalmology Microsurgery Course For Medical Students, Michael Y. Zhu, Keke Liu, Joanne C. Wen, Sandra Stinnett, Jullia A. Rosdahl Aug 2025

Education Outcomes From An Ophthalmology Microsurgery Course For Medical Students, Michael Y. Zhu, Keke Liu, Joanne C. Wen, Sandra Stinnett, Jullia A. Rosdahl

Journal of Academic Ophthalmology

Background: Microsurgery training programs are critical for developing the skills needed by ophthalmology residents, but they are not typically offered to medical students. However, incorporating a microsurgery course into medical school curricula may help students more carefully consider a career in ophthalmology and improve learning outcomes during their training. Purpose: This article describes a microsurgery course for medical students and evaluates its educational impact. Methods: A microsurgery course was developed and implemented for third (MS3) and fourth (MS4) year medical students at Duke University School of Medicine. The fourweek course included six didactic lectures, three hands-on skills sessions, and the …


Patterns Of Ophthalmology-Related Interfacility Transfers To The Emergency Department By Temporal Trends, Laura E. Ramirez, Michael Waxman, Denis R. Pauze, Edward J. Wladis Aug 2025

Patterns Of Ophthalmology-Related Interfacility Transfers To The Emergency Department By Temporal Trends, Laura E. Ramirez, Michael Waxman, Denis R. Pauze, Edward J. Wladis

Journal of Academic Ophthalmology

Background: Interfacility transfer patients are associated with inferior outcomes, higher costs, and emergency department (ED) overcrowding. Previous studies have analyzed the general trends influencing interfacility transfers, but the patterns affecting ophthalmology-related transfer rates remain unclear. The purpose of this study was to identify and quantify the patterns of interfacility ophthalmology-specific transfers to the ED by temporal trends and to determine the type of ophthalmic services required by the transferred population.

Methods: All patients transferred to the ED of a single level 1 trauma center because of ophthalmology-related complaints from 2016 to 2023 were analyzed retrospectively. Transfer and nontransfer …


A Bibliometric Analysis Of The Top 100 Cited Papers In Trabeculectomy, Sinan Akosman, Michael Frenkel, Sonia C. Mcnamara, Thomas I. Hong, Reena A. Garg Aug 2025

A Bibliometric Analysis Of The Top 100 Cited Papers In Trabeculectomy, Sinan Akosman, Michael Frenkel, Sonia C. Mcnamara, Thomas I. Hong, Reena A. Garg

Journal of Academic Ophthalmology

Purpose: To identify the most frequently cited articles on trabeculectomy through a bibliometric analysis. Methods: The Web of Science was queried using the term “trabeculectomy” to identify the 100 most cited (T100) publications. Articles were listed by title, authors’ affiliated institutions, journal title, year of publication, country of origin, funding sources, and citation count. Results: The T100 articles were published between the years 1975 and 2022. The number of total citations received by each article ranged from 83 to 550. The number one most cited T100 article was titled “Treatment Outcomes in The Tube Versus Trabeculectomy (TVT) Study After Five …