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Citrullinated Eno1 Vaccine Enhances Pd-1 Blockade In Mice Implanted With Murine Triple-Negative Breast Cancer Cells, Ricardo A León-Letelier, Alejandro M Sevillano-Mantas, Yihui Chen, Soyoung Park, Jody Vykoukal, Johannes F Fahrmann, Edwin J Ostrin, Candace Garrett, Rongzhang Dou, Yining Cai, Fu-Chung Hsiao, Jennifer B Dennison, Eduardo Vilar, Banu K Arun, Samir Hanash, Hiroyuki Katayama Jun 2025

Citrullinated Eno1 Vaccine Enhances Pd-1 Blockade In Mice Implanted With Murine Triple-Negative Breast Cancer Cells, Ricardo A León-Letelier, Alejandro M Sevillano-Mantas, Yihui Chen, Soyoung Park, Jody Vykoukal, Johannes F Fahrmann, Edwin J Ostrin, Candace Garrett, Rongzhang Dou, Yining Cai, Fu-Chung Hsiao, Jennifer B Dennison, Eduardo Vilar, Banu K Arun, Samir Hanash, Hiroyuki Katayama

Faculty, Staff and Student Publications

Background/Objectives:Cancer vaccine targets mostly include mutations and overexpressed proteins. However, cancer-associated post-translational modifications (PTMs) may also induce immune responses. Previously, our group established the enzyme protein arginine deiminase type-2 (PADI2), which catalyzes citrullination modification, is highly expressed in triple-negative breast cancer (TNBC), promoting antigenicity.

Methods: Here, we show the workflow of designing citrullinated enolase 1 (citENO1) vaccine peptides identified from breast cancer cells by mass spectrometry and demonstrate TNBC vaccine efficacy in the mouse model. Immunized mice with citENO1 peptides or the corresponding unmodified peptides, plus Poly I:C as an adjuvant, were orthotopically implanted with a TNBC murine …


Mapping Vascular Network Architecture In Primate Brain Using Ferumoxytol-Weighted Laminar Mri, Joonas A Autio, Ikko Kimura, Takayuki Ose, Yuki Matsumoto, Masahiro Ohno, Yuta Urushibata, Takuro Ikeda, Matthew F Glasser, David C Van Essen, Takuya Hayashi Jun 2025

Mapping Vascular Network Architecture In Primate Brain Using Ferumoxytol-Weighted Laminar Mri, Joonas A Autio, Ikko Kimura, Takayuki Ose, Yuki Matsumoto, Masahiro Ohno, Yuta Urushibata, Takuro Ikeda, Matthew F Glasser, David C Van Essen, Takuya Hayashi

2020-Current year OA Pubs

Mapping the vascular organization of the brain is of great importance across various domains of basic neuroimaging research, diagnostic radiology, and neurology. However, the intricate task of precisely mapping vasculature across brain regions and cortical layers presents formidable challenges, resulting in a limited understanding of neurometabolic factors influencing the brain's microvasculature. Addressing this gap, our study investigates whole-brain vascular volume using ferumoxytol-weighted laminar-resolution multi-echo gradient-echo imaging in macaque monkeys. We validate the results with published data for vascular densities and compare them with cytoarchitecture, neuron and synaptic densities. The ferumoxytol-induced change in transverse relaxation rate (ΔR


Cy Empire Corp. V. Esther Mcintosh Jun 2025

Cy Empire Corp. V. Esther Mcintosh

All Decisions

The court granted a tenant's motion to dismiss a non-primary residence holdover proceeding against her. The landlord improperly used the pseudonym "Jane Doe" in the pleadings in violation of CPLR 1024. To use a fictitious name, a petitioner must submit an affidavit detailing the genuine efforts made to ascertain the party's identity. Here, the landlord's affidavit was silent regarding any effort to identify the occupant, who was a known party from prior proceedings. The landlord's cross-motion to amend the caption to substitute the tenant's real name was denied as prejudicial.


Strategies For Reducing Cost Overruns On Government-Funded Infrastructure Projects In Jamaica, Owen Whitely Jun 2025

Strategies For Reducing Cost Overruns On Government-Funded Infrastructure Projects In Jamaica, Owen Whitely

Walden Dissertations and Doctoral Studies

Cost overruns involving government-funded infrastructure projects have the potential to lead to adverse economic and social outcomes. Project managers and government administrators are concerned with cost overruns as they often lead to delays, resource misallocation, and decreased public trust. Grounded in the theory of constraints, the purpose of this qualitative pragmatic inquiry was to explore strategies project managers use to reduce cost overruns for government-funded infrastructure projects in Jamaica. Participants were five project managers working on large-scale infrastructure projects with experience effectively mitigating cost overruns in Jamaica. Data were collected through in-depth semistructured interviews, government documents, and public records. Five …


Morphological And Physiological Responses Of Cymbopogon Citratus And Pennisetum Alopecuroides To Saline Water Irrigation, Haifeng Xing, Asmita Paudel, Julie Hershkowitz, Youping Sun Jun 2025

Morphological And Physiological Responses Of Cymbopogon Citratus And Pennisetum Alopecuroides To Saline Water Irrigation, Haifeng Xing, Asmita Paudel, Julie Hershkowitz, Youping Sun

Plants, Soils, and Climate Faculty Publications

Reclaimed water provides a sustainable and economical alternative for landscape irrigation, but its elevated salinity can negatively impact sensitive plant species. This study evaluated the salinity tolerance of two widely used ornamental grasses, Cymbopogon citratus (lemon grass) and Pennisetum alopecuroides (fountain grass), under three electrical conductivity (EC) levels: 1.2 (control), 5.0, and 10.0 dS·m−1. Visual assessments over 62 days showed that both species maintained an acceptable appearance under saline conditions. C. citratus exhibited no foliar damage, with visual scores above 4.6 even at 10.0 dS·m−1, whereas P. alopecuroides showed slight leaf injury but retained a score …


Modernism’S Mythic Mothers: Queering Motherhood Through Classical Matrilineage, Samantha Marie Lepak Jun 2025

Modernism’S Mythic Mothers: Queering Motherhood Through Classical Matrilineage, Samantha Marie Lepak

Dissertations

I position this dissertation at the intersection of modern/contemporary literature, queer/feminist theory, and ancient Greek classics in the hopes of better understanding the spaces in which they meet, engaging with writers from the late modernist era to the present in order to highlight the connections between theories, themes, and practices of queerness from the modernists forward. Using the work of H.D. and writers following in her footsteps, I argue that exploring adaptations of Greek classics written primarily by female and gender-variant authors from the modernist era forward illuminates the extent to which the classics enables writers to “think queerly,” considering …


Maternal Access For Depression In Rural Environments, Simone Parlier Jun 2025

Maternal Access For Depression In Rural Environments, Simone Parlier

Dissertations

Significance –As many as 25% of birthing persons experience postpartum depression (PPD) within the first year after childbirth making this one of the most common postpartum disorders. PPD is prevalent, incapacitating, and treatable. The first step is identifying those at risk. Rural birthing persons are understudied, and may have unique predisposing characteristics as well as geographic challenges for optimal detection and treatment of PPD. Purpose -The long-term goal is to improve the health of rural families. Using The Theory of Unpleasant Symptoms, the purpose of this descriptive, cross-sectional research was to describe the prevalence of PPD in rural birthing persons …


Ethnicity Through Education: An Analysis Of The Influence Of Formal Education On Ethnicity In Garo Hills, Samirkumar Benedict Talati Jun 2025

Ethnicity Through Education: An Analysis Of The Influence Of Formal Education On Ethnicity In Garo Hills, Samirkumar Benedict Talati

Dissertations

In recent decades, the positioning of ethnic groups within the educational context has emerged as an important area of scholarly investigation. The structural, institutional, and local contexts often determine how ethnic groups shape their ethnicity. This study draws from panethnicity and social ontology frameworks to examine ethnic consciousness and the processes of solidarity-building across subgroups within the Garo community in the Garo Hills of Meghalaya. The unequal distribution of educational resources has led to socioeconomic disparities and class formation within Garo society, creating a growing divide between the educated and uneducated Garos. While acknowledging the diversity among subgroups, this study …


Exploring Latinx Students' Experience With School Connectedness: A Hybrid Thematic Approach To Deductive And Inductive Analysis, Maria Olivia Mendez Jun 2025

Exploring Latinx Students' Experience With School Connectedness: A Hybrid Thematic Approach To Deductive And Inductive Analysis, Maria Olivia Mendez

Dissertations

This qualitative study aimed to deepen the understanding of school connectedness experienced by Latinx high school students. Specifically, the researcher sought to explore how Latinx students described their connection to school during their high school years. Additionally, to examine whether their experiences aligned with the social and ecological structures outlined in the theoretical model supporting adolescent connectedness to school. If there is alignment, in what ways did it manifest? If not, how did the experiences differ? The study had two primary objectives: (a) to gain insight into how Latinx students experienced school and their sense of connection through their narratives, …


On The Concepts Of Modern And Archaic, Augusto Boal Jun 2025

On The Concepts Of Modern And Archaic, Augusto Boal

Spect-actor: A Journal of Pedagogy & Theatre of the Oppressed

No abstract provided.


Editors' Introduction To The 8th Volume Of The Pto Journal, Pto Journal Editor Jun 2025

Editors' Introduction To The 8th Volume Of The Pto Journal, Pto Journal Editor

Spect-actor: A Journal of Pedagogy & Theatre of the Oppressed

No abstract provided.


Environmental Migration And Governance Deficiencies - A Topic Worth Attention, Dr. Friedarike Santner Jun 2025

Environmental Migration And Governance Deficiencies - A Topic Worth Attention, Dr. Friedarike Santner

Future Journal of Social Science

No abstract provided.


Roles Of Nigerian Ulama In Politics And Nation-Building: The Controversy, Achievements And Recommendations, Abdulkadir Salaudeen, Saidu Ahmad Dukawa Jun 2025

Roles Of Nigerian Ulama In Politics And Nation-Building: The Controversy, Achievements And Recommendations, Abdulkadir Salaudeen, Saidu Ahmad Dukawa

Future Journal of Social Science

Religion and politics in Islam are not watertight compartments. In Islam, it is impossible to separate the state from religion because Islam is a state in the political sense and a religion in the spiritual sense. It is true that state-religion-separation is the norm in the secularist West. It is not true in Islam where state and Islam are indivisibly connected. Despite the interconnectedness between Islam and politics, a lot of people see participation of ulama in politics as an abomination due to the current of apolitical Islam that is sweeping across the circle of ulama. Focusing on Nigeria, this …


The Plight Of The Farmer Leaflet Jun 2025

The Plight Of The Farmer Leaflet

Eartha M. M. White Textual Material

Leaflet: Women's Christian Temperance Union flyer. Undated.


Customer Prioritization: From Conceptualization To International Application, Maria Gracner, John William Cadogan, Gregor Pfajfar Jun 2025

Customer Prioritization: From Conceptualization To International Application, Maria Gracner, John William Cadogan, Gregor Pfajfar

Economic and Business Review

This study examines customer prioritization, a strategic practice where businesses allocate resources and efforts based on customer value. While its significance in international marketing continues to grow, limited research exists on how customer prioritization is understood and applied in international firms operating across diverse cultural contexts. Addressing this gap, the study explores how international-marketing managers conceptualize customer prioritization and identifies its key components. Using a qualitative methodology, the study conducted in-depth interviews with Slovene international-marketing and sales managers from 13 export-oriented firms. Thematic analysis, guided by the Gioia methodology, identified four central themes: prioritization tactics and strategies, international customer profitability, …


Comparison Of Two Injection Techniques On Pain Perception Among Adult Patients Receiving Intramuscular Injection: A Randomized Controlled Trial, Dr.Sindhu L, Dr. Bindu R. Nayar, Dr. Rajamohanan Pillai K Jun 2025

Comparison Of Two Injection Techniques On Pain Perception Among Adult Patients Receiving Intramuscular Injection: A Randomized Controlled Trial, Dr.Sindhu L, Dr. Bindu R. Nayar, Dr. Rajamohanan Pillai K

Manipal Journal of Nursing and Health Sciences

Introduction: The administration of intramuscular injection is a common procedure performed by nurses that causes pain to the patient. The way nurses administer injections is one of the factors associated with increased client discomfort. Aspiration has been ingrained in the intramuscular injection procedure, and even though many policies no longer endorse it, it is often frequently taught and used. Injections without aspiration are considered more comfortable for patients. Aspiration in the injection is a controversy concerning its perceived benefits and indications due to a paucity of available data, there is no evidence that this procedure is essential or truly …


Neural Engineering In Action: Exploring Muscle Movement Through Data And Design, Dr. Ashwin Mohan, Dr. Sowmya Anjur, Mrs. Namrata Pandya, Matthew Stroud, Dr. David Bergin Emeritus, Dr. Satish Nair Jun 2025

Neural Engineering In Action: Exploring Muscle Movement Through Data And Design, Dr. Ashwin Mohan, Dr. Sowmya Anjur, Mrs. Namrata Pandya, Matthew Stroud, Dr. David Bergin Emeritus, Dr. Satish Nair

2025

No abstract provided.


Jean Prillman V. George Parsons Jun 2025

Jean Prillman V. George Parsons

2025 Decisions

USDC for the Eastern District of Pennsylvania


Daniel Andrews,Sr. V. Pennsylvania Department Of Corrections Jun 2025

Daniel Andrews,Sr. V. Pennsylvania Department Of Corrections

2025 Decisions

USDC for the Middle District of Pennsylvania


Towards A Robust Hydrologic Data Assimilation System For Hurricane-Induced River Flow Forecasting, Peyman Abbaszadeh, Fatemah Gholizadeh, Keyhan Gavahi, Hamid Moradkhani Jun 2025

Towards A Robust Hydrologic Data Assimilation System For Hurricane-Induced River Flow Forecasting, Peyman Abbaszadeh, Fatemah Gholizadeh, Keyhan Gavahi, Hamid Moradkhani

Civil and Environmental Engineering Faculty Publications and Presentations

The Hybrid Ensemble and Variational Data Assimilation framework for Environmental Systems (HEAVEN) is a method developed to enhance hydrologic model predictions while accounting for different sources of uncertainties involved in various layers of model simulations. While the effectiveness of this data assimilation in forecasting streamflow has been proven in previous studies, its potential to improve flood forecasting during extreme events remains unexplored. This study aims to demonstrate this potential by employing HEAVEN to assimilate streamflow data from United States Geological Survey (USGS) stations into a conceptual hydrologic model to enhance its capability to forecast hurricane-induced floods across multiple locations within …


Matter Of Promenade Nelson Apts. Llc V. New York State Div. Of Hous. & Community Renewal Jun 2025

Matter Of Promenade Nelson Apts. Llc V. New York State Div. Of Hous. & Community Renewal

All Decisions

In an Article 78 proceeding regarding a Major Capital Improvement (MCI) rent increase, the appellate court reversed a lower court's denial of the landlord's petition. The court held that while DHCR's retroactive application of the HSTPA to the landlord's pending MCI application was rational, the agency failed to establish a rational basis for its determination that certain installations exceeded the scope of necessary work. The matter was remanded to DHCR because the agency also failed to address the merits of the landlord's argument that the disputed costs were required for code compliance.


Gregory Janicki V. Washington Township Board Of Education Jun 2025

Gregory Janicki V. Washington Township Board Of Education

2025 Decisions

USDC for the District of New Jersey


Eric Bartoli V. Director Federal Bureau Of Prisons Jun 2025

Eric Bartoli V. Director Federal Bureau Of Prisons

2025 Decisions

USDC for the Western District of Pennsylvania


In Re: Nfl Players Concussion Injury Litigation Jun 2025

In Re: Nfl Players Concussion Injury Litigation

2025 Decisions

USDC for the Eastern District of Pennsylvania


Edc 3100 Social Science In Childhood Education Spring 2025 Syllabus, Ivana Espinet Jun 2025

Edc 3100 Social Science In Childhood Education Spring 2025 Syllabus, Ivana Espinet

Open Educational Resources

This course is designed to provide students with an introduction to the standards, curricula, and methods of teaching social studies in a childhood setting. The students will learn pedagogical strategies and develop critical thinking skills concerning curriculum content and the creation and implementation of classroom activities.


Legal Geographies Of Mapuche-Williche Ancestral Waters: Real Estate Development And Contested Jurisdiction In Riparian Areas, Adamari Benavidez Jun 2025

Legal Geographies Of Mapuche-Williche Ancestral Waters: Real Estate Development And Contested Jurisdiction In Riparian Areas, Adamari Benavidez

Geography Undergraduate Senior Theses

In the Wallmapu (ancestral Mapuche territory) of southern Chile, river and lakefront real estate development is often promoted by state institutions and developers as conservation or eco-tourism. However, these inmobiliaria projects are part of a longer trajectory of settler colonial jurisdiction, historically materialized through the dispossession of Mapuche-Williche territory. In the Maihue–Ranco subwatershed, this encroaching development are sparking increasing conflict with Mapuche-Williche lof (community), as developers and residents engage in extralegal practices—diverting waterways, denying access to lakefronts, surveilling mobility—that are fundamentally incompatible with Mapuche territorial order (Azmapu).

In this thesis I ask: (i) What spatial and legal strategies …


Insights Into The Floral Senescence Effects Of Nanoparticles, Vuk Uskoković Jun 2025

Insights Into The Floral Senescence Effects Of Nanoparticles, Vuk Uskoković

Administration and Staff Articles and Research

Flowers could be valuable addenda to nanomedicine labs as in vivo models crossing the gap between the cell culture and small mammals. However, as it is shown here, floral models continue to be predominantly utilized within resource-limited research environments and remain largely underrepresented in mainstream biomedical investigations conducted by well-funded institutions in the developed world. The ability to delay the senescence of Orange Jubilee wildflowers was tested here on three types of nanoparticles: selenite-doped hydroxyapatite (HAp), citrate-stabilized HAp, and superparamagnetic iron oxide. Integration of selenite into the HAp crystal lattice produced a mild increase in the senescence rate …


Cardozo Celebrates The Class Of 2025 At 47th Commencement, Benjamin N. Cardozo School Of Law Jun 2025

Cardozo Celebrates The Class Of 2025 At 47th Commencement, Benjamin N. Cardozo School Of Law

Cardozo Law News Archive

On June 4, 2025, Cardozo celebrated its 47th Commencement at Lincoln Center’s David Geffen Hall, conferring degrees on 304 J.D. graduates and 83 LL.M. graduates. Dean Melanie Leslie ’91 reminded students of their responsibility to uphold the Constitution, while keynote speaker Hon. Caitlin J. Halligan urged them to pursue meaningful paths in the law. Student speakers Koral Bahat, Denise Pasi, and Talia Raoufpur reflected on resilience, diversity, and community. Yeshiva University President Rabbi Dr. Ari Berman encouraged graduates to lead with integrity and purpose.

The ceremony also honored faculty and administrators with awards for excellence in teaching, service, and student …


Ocean Acidification Decreases Molting But Not Survival Of Antarctic Amphipods Djerboa Furcipes, Gondogeneia Antarctica, And Prostebbingia Gracilis, Hannah E. Oswalt, Margaret O. Amsler, Charles D. Amsler, Julie Schram, James B. Mclintock, Paul A. Baker Jun 2025

Ocean Acidification Decreases Molting But Not Survival Of Antarctic Amphipods Djerboa Furcipes, Gondogeneia Antarctica, And Prostebbingia Gracilis, Hannah E. Oswalt, Margaret O. Amsler, Charles D. Amsler, Julie Schram, James B. Mclintock, Paul A. Baker

Faculty, Staff, and Students

Ocean acidification refers to a decrease in the pH of the world’s oceans from the oceanic uptake of human-derived atmospheric CO2. Low pH is known to decrease the calcification and survival of many calcifying invertebrates. Shallow, hard bottom communities along the Western Antarctic Peninsula often have incredibly large numbers of invertebrate mesograzers that shelter on and are mutualists with the dominant brown macroalgae. The common amphipod species Djerboa furcipes, Gondogeneia antarctica, and Prostebbingia gracilis were collected from the immediate vicinity of Palmer Station, Antarctica (64°46′S, 64°03′W) in January–February 2023 and maintained under three different pH treatments simulating ambient conditions (approximately …


Real Estate Board Of New York, Inc. V. The City Of New York Jun 2025

Real Estate Board Of New York, Inc. V. The City Of New York

All Decisions

The court denied a preliminary injunction against New York City's FARE Act, which shifts broker fee payment from tenants to landlords. The judge granted in part the City's motion to dismiss, striking down plaintiffs' First Amendment, New York State Constitution, and state law preemption claims. However, the Contracts Clause claim was allowed to proceed. The court emphasized that it cannot overturn legislation based on policy disagreements.