Digital Commons Network^™

Chem 125-103: General Chemistry I, Sean Lee

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 243-H01: Honors Organic Chemistry I, Christopher Desantis

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 244a-001: Organic Chemistry I Lab, Alfredo Castro

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 473-001: Biochemistry, Bhavani Balasubramanian

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 702-101: Special Topics: Spectrometric Identification Of Organic Componds, Carlos Pacheco

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Biol 644-001: Physiological Mechanisms, John Yarotsky

Biology Syllabi

No abstract provided.

On Frand-Ly Terms: Examining The Role Of Juries In Standard-Essential Patent Disputes, Marta Krason

University of Chicago Law Review

Modern society relies on interconnected technologies, and interoperability has become crucial for meeting consumer expectations. Technology standards have emerged to ensure compatibility and interoperability across products. Once an industry selects a standard as the default for consumers and businesses, industry players begin to adapt it, often phasing out alternative—sometimes even superior— technologies. Holders of patents covering technology standards, known as standard- essential patents (SEPs), control the rights to an invention with no commercially viable alternative or that cannot be designed around while still complying with a standard. This gives SEP holders significant leverage in licensing negotiations

Standards development organizations (SDOs) …

Eugenics And Polygenic Embryo Screening: Public, Clinician, And Patient Perceptions Of Conditions Versus Traits, Dorit Barlevy, Rémy A Furrer, Asha Kalapatapu, Abigail Martinez, Todd Lencz, Shai Carmi, Gabriel Lázaro-Muñoz, Stacey Pereira

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Polygenic embryo screening (PES) estimates an embryo's genetic chances of developing complex conditions (eg, cancer) and traits (eg, height). Stakeholders have raised concerns that PES promotes eugenic practices and ideology.

Methods: We surveyed a nationally representative sample of the US public on approval of screening embryos for 12 conditions and 12 traits and examined the association between disapproval and concern about eugenics. We also conducted semistructured interviews with US-based reproductive endocrinology and infertility specialists and patients undergoing in vitro fertilization on their perspectives toward PES.

Results: Among the US public (n = 1423), disapproval of screening embryos for traits …

Prenatal Genetic Consultation And Testing, Sarah Araji, Lauren Westerfield, Roni Zemet, Ignatia B Van Den Veyver

Duncan NRI Faculty and Staff Publications

The evolution of prenatal genetic testing has transformed prenatal diagnosis into a more precise and individualized approach. Advanced tools such as chromosomal microarray analysis and exome sequencing have enabled the prenatal diagnosis of more genetic conditions, including anomalies and disorders eligible for fetal therapy. When in utero therapy is considered, accurate genetic diagnosis is essential for guiding providers' and patients' decisions regarding management and outcomes. This chapter reviews available prenatal genetic screens and tests, their indications, and counseling strategies. It also explores genetic abnormalities associated with fetal structural anomalies and their implications for decision-making in fetal interventions.

Indigenous Women’S Reproductive Traditions: Reclaiming Sovereignty Through 500 Years Of Colonization, Stephanie A. Sellers

Gettysburg College Faculty Books

In Indigenous Women’s Reproductive Traditions, Stephanie Sellers delves into the rich history of Indigenous women’s reproductive practices before European colonization. The book highlights traditional methods such as birth control, abortion, and child spacing, which were integral to maintaining agency over their bodies. Sellers explores how these practices were disrupted by European patriarchal structures and examines the impact of forced sterilization in the 20th century. Today, Indigenous women are reclaiming their rights through movements for reproductive justice, advocating for a return to their ancestral practices and redefining concepts of womanhood and motherhood on their own tribal terms.

Self-Colonization In American Law: The Internet And Personal Information Example, Daniel J.H. Greenwood

Hofstra Law Faculty Scholarship

Since the Reagan era, American economic policy has amounted to self-colonization. Democratic majorities have consistently supported legal regimes that have enabled corporations to extract the lion’s share of the gains from trade from the public. For example, they have supported a corporate law regime that denies the public democratic control over the behavior of corporations and instead gives dictatorial powers to shareholders and managers. The Internet has made it even easier for firms to extract surpluses from consumers through surveillance and algorithmic pricing. One small contribution toward a project of decolonizing the public would be for consumers to obtain a …

Proposed Cloud Services Sourcing Rule: The Right Direction, Reuven Avi-Yonah, Jeffery M. Kadet, Karen Sam

Articles

This past January, in conjunction with the issuance of a final regulation (T.D. 10022) that treats income from defined cloud transactions as income from services, Treasury and the IRS released a proposed regulation (REG-107420-24) on the sourcing of that income. In 2019 a Treasury official had asked the tax community for feedback on whether specific cloud transaction sourcing rules were needed, and the preamble to a 2019 proposed regulation asked for comments on “administrable rules for sourcing income from cloud transactions in a manner consistent with sections 861 through 865.” The feedback was “split almost evenly with regard to whether …

Evaluating The Consistency Of Smarcb1 Variant Classification And Assertions Of Genotype-Phenotype Relationships In Clinvar, Samarth Satish, Matan Bone, Deborah Ritter, Sharon E Plon

Faculty, Staff and Students Publications

Pathogenic SMARCB1 variants are associated with multiple Mendelian syndromes: Schwannomatosis (SM), Rhabdoid Tumour Predisposition Syndrome (RTPS1), and/or Coffin-Siris Syndrome (CSS). Although some data suggests genotype/phenotype relationships based on mutation type and location, this is not used consistently potentially due to inconsistent or absent phenotypic data. We used ClinVar, the largest public platform of variant classifications, to evaluate variant-specific data from clinical laboratories and cited publications to assess reporting consistency and genotype-phenotype relationships. When available, we extracted the mutation type, HGVS nomenclature, submitters, publications, and disease conditions. We compared the disease assertions made by laboratory submissions with those made in cited …

Irp Commercial Trailer Data Feasibility Study, Brian Howell, Jennifer Walton

Kentucky Transportation Center Research Report

This study evaluates the feasibility for developing and maintaining a comprehensive tractor truck trailer database. The commercial motor vehicle (CMV) community currently lacks a cross-jurisdictional, centralized repository for commercial trailers registered in United States and Canadian jurisdictions. Existing federal databases provide information on interstate commercial motor carriers, vehicles, and drivers but exclude trailers. Similarly, IRP and IFTA do not collect trailer-level data, and trailer data is displayed inconsistently across its customer base. Approximately one fifth of violations in Kentucky during inspections from 2020 to 2022 were attributed to trailers, including worn tires, inadequate brakes or improper registration. The rise of …

Minimally Invasive, Bioadaptive Multimodal Sensor Probe With Safe Deployment For Real-Time Acute Compartment Syndrome Diagnosis, Seung Gi Seo, Amanda M Westman, William Moritz, Joseph Ribaudo, Mitchell A Pet, Et Al.

2020-Current year OA Pubs

Acute Compartment Syndrome (ACS) is a serious medical condition that arises from increased pressure within osteofascial compartments, leading to impaired blood flow and potential tissue damage. Early and accurate diagnosis is critical for preventing permanent damage. Current methods rely largely on qualitative assessments with limited accuracy, and those that exploit invasive pressure measurements often prove inadequate. Herein, a soft materials-based multimodal sensor probe is introduced, as well as the mechanical and thermal influences to monitor intra-compartmental pressure, tissue oxygen saturation (StO

S1pr1 Regulates Lymphatic Valve Development And Tertiary Lymphoid Organ Formation In The Ileum, Xin Geng, Gwendalyn J Randolph, Et Al.

2020-Current year OA Pubs

Efficient lymph flow is ensured by lymphatic valves (LVs). The mechanisms that regulate LV development are incompletely understood. Here, we show that the deletion of the GPCR sphingosine 1-phosphate receptor-1 (S1PR1) from lymphatic endothelial cells (LECs) results in fewer LVs. Interestingly, LVs that remained in the terminal ileum-draining lymphatic vessels were specifically dysfunctional. Furthermore, tertiary lymphoid organs (TLOs) formed in the terminal ileum of the mutant mice. TLOs in this location are associated with ileitis in humans and mice. However, mice lacking S1PR1 did not develop obvious characteristics of ileitis. Mechanistically, S1PR1 regulates shear stress signaling and the expression of …

Machine Learning Feasibility In Cochlear Implant Speech Perception Outcomes-Moving Beyond Single Biomarkers For Cochlear Implant Performance Prediction, Matthew A. Shew, Cole Pavelchek, Andrew Michelson, Amanda Ortmann, Shannon Lefler, Amit Walia, Nedim Durakovic, Alisa Phillips, Ayna Rejepova, Jacques A. Herzog, Phillip Payne, Jay F. Piccirillo, Craig A. Buchman

2020-Current year OA Pubs

OBJECTIVES: Machine learning (ML) is an emerging discipline centered around complex pattern matching and large data-based prediction modeling and can improve precision medicine healthcare. Cochlear implants (CI) are highly effective, however, outcomes vary widely, and accurately predicting speech perception performance outcomes between patients remains a challenge. This study aims to evaluate the ability of ML to predict speech perception performance among CI recipients at 6-month post-implantation using only preoperative variables on one of the largest CI datasets to date, with an emphasis placed on identification of poor performers.

DESIGN: All patients enrolled in the national CI outcome tracking database, HERMES, …

Analysis Of Traffic Crash Data In Kentucky 2020-2024, Paul Ross, Eric Green, Christopher Blackden, Christopher Van Dyke

Kentucky Transportation Center Research Report

No abstract provided.

From Structure To Specificity: Biophysical Characterization Of Functional Interfaces In Protein Systems, Logan M. Brown

Doctoral Dissertations

Proteins are nature’s dynamic molecular machines, operating across a spectrum from highly ordered scaffolds to intrinsically disordered systems, and executing functions that depend on both precise structures and conformational flexibility. Yet, the mechanistic rules linking sequence, structure, and activity particularly in disordered proteins and specialized functional adaptations remain incompletely understood. This dissertation addresses that gap by integrating structural biology, biophysics, and protein engineering to dissect molecular recognition, stability, and function across three diverse yet thematically connected protein systems. Building on this understanding of protein structure and function, the following four projects apply these concepts to address diverse biological questions, ranging …

Investigations Into Prior Knowledge And Self-Efficacy As Predictors Of Exam Performance In General Chemistry, And Student Interactions With Chemistry Textbooks, Gordon Hunter

Doctoral Dissertations

The first chapter addresses the validity and reliability of the Motivated Strategies for Learning Questionnaire (MSLQ) as a tool for chemistry education research. The study shows that the original MSLQ did not meet modern standards of reliability and presents a modified version that better captures self-efficacy in chemistry-specific contexts. The revised instrument shows improved model fit, reinforcing the importance of refining assessment tools for chemistry education research.The effects of prior knowledge and self-efficacy on student performance in a first-semester general chemistry course are investigated in the second chapter. Self-efficacy, defined as a learner's belief in their capability to successfully accomplish …

Multi-Level Characterization And Testing Of Fatigue, Fracture And Creep Of The Ultra-High Strength Low-Alloy Steel Fabricated Via Laser Powder Bed Fusion, Nemanja Kljestan

Doctoral Dissertations

This dissertation presents a comprehensive experimental investigation of the mechanical behavior of an high-strength low-alloy (HSLA) steel fabricated via laser powder bed fusion (LPBF). The work focuses on fatigue strength, laser shock peening (LSP) effects, creep behavior, fatigue crack growth and fracture toughness. Fatigue strength was assessed using rotating bending tests, showing superior performance of LPBF specimens compared to as-cast materials due to the dual-variant martensitic microstructures. Laser shock peening enhanced fatigue life by inducing compressive residual stresses, delaying crack initiation and slowing crack propagation. Creep behavior was evaluated for different layer thicknesses, with thinner layers improving secondary creep resistance …

Eastern Oyster, Crassostrea Virginica, Genomics In A Well-Mixed Estuarine System: Examining Population Structure, Viability, And Response To Stressors, Alyssa Strickland

Doctoral Dissertations

Eastern oysters, Crassostrea virginica, are foundational estuarine species that contribute to a variety of ecosystem services including water filtration, nutrient cycling, habitat creation, and shoreline protection. However, populations have declined due to disease, overharvesting, habitat loss, and climate change, especially in northern systems such as New Hampshire’s Great Bay Estuary (GBE), located in the Gulf of Maine, one of the world’s fastest warming waters. This dissertation uses genomic and transcriptomic approaches to understand the drivers of population structure, decline, and resilience in GBE oyster populations, aiming to aid restoration and aquaculture. Chapter 1 used low-coverage whole-genome sequencing to understand population …

Mckee Minute September 2025, Southern Adventist University

McKee Minute – McKee Library This Month

The September 2025 edition of McKee Minute includes information on digital newspaper access, information literacy modules, Libby account updates, and Hispanic Heritage Month.

Frsc 498-001: St: Forensic Anthropology, Sai Casadozapico

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 125-017: General Chemistry I, Kevin Koh

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 121-001: Funds Of Chemical Principles I, Gregory Edens

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 121-003: Fund Of Chemical Principles I, Gregory Edens

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Frsc 365-101: Mobile Forensics, John Lucich

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Eps 202-451: Technology, And Environment, Michael Bonchonsky

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 126-005: General Chemistry Ii, Gregory Edens

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.