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The Files Are In The Computer: On Copyright, Memorization, And Generative Ai, A. Feder Cooper [email protected], James Grimmelmann Aug 2025

The Files Are In The Computer: On Copyright, Memorization, And Generative Ai, A. Feder Cooper [email protected], James Grimmelmann

Chicago-Kent Law Review

No abstract provided.


Creative Machines: Generative Artificial Intelligence And Copyright Law, Ryan Abott, Elizabeth Rothman [email protected] Aug 2025

Creative Machines: Generative Artificial Intelligence And Copyright Law, Ryan Abott, Elizabeth Rothman [email protected]

Chicago-Kent Law Review

No abstract provided.


The Ai-Copyright Trap, Carys J. Craig Aug 2025

The Ai-Copyright Trap, Carys J. Craig

Chicago-Kent Law Review

No abstract provided.


Keeping Cruises At Bay: Whether Port Cities Violate The Dormant Commerce Clause And Federal Maritime Law, Julie Jacobs Aug 2025

Keeping Cruises At Bay: Whether Port Cities Violate The Dormant Commerce Clause And Federal Maritime Law, Julie Jacobs

Chicago-Kent Law Review

No abstract provided.


Bad, Bad Medicine—When A State’S Healthcare Infrastructure Violates The Integration Mandate Of The Americans With Disabilities Act, Anna Ylitalo Aug 2025

Bad, Bad Medicine—When A State’S Healthcare Infrastructure Violates The Integration Mandate Of The Americans With Disabilities Act, Anna Ylitalo

Chicago-Kent Law Review

No abstract provided.


A Principle Of Artistic Data Sovereignty: Linking Creative Reuse To Author Remuneration, Georgia Jenkins Aug 2025

A Principle Of Artistic Data Sovereignty: Linking Creative Reuse To Author Remuneration, Georgia Jenkins

Chicago-Kent Law Review

No abstract provided.


Artificial Intellectual Property, Daniel J. Gervais Aug 2025

Artificial Intellectual Property, Daniel J. Gervais

Chicago-Kent Law Review

No abstract provided.


Trade Secrecy Meets Generative Ai, Camilla A. Hrdy Aug 2025

Trade Secrecy Meets Generative Ai, Camilla A. Hrdy

Chicago-Kent Law Review

No abstract provided.


Erick Osbelli Garcia-Mantar V. Attorney General United States Of America Aug 2025

Erick Osbelli Garcia-Mantar V. Attorney General United States Of America

2025 Decisions

Agency


Jose Ramos Jimenez V. Attorney General United States Of America Aug 2025

Jose Ramos Jimenez V. Attorney General United States Of America

2025 Decisions

Agency


Anselmo Millan V. Municipality Of Harrison Aug 2025

Anselmo Millan V. Municipality Of Harrison

2025 Decisions

USDC for the District of New Jersey


A Xeno-Free Protocol For Rapid Differentiation Of Human Ipsc-Derived Microglia From The Kolf2.1j Reference Line., Nélio A J Oliveira, Katherine R Lewkowicz, Patricia A Clow, Michael E Ward, Mark R Cookson, William C Skarnes, Justin A Mcdonough Aug 2025

A Xeno-Free Protocol For Rapid Differentiation Of Human Ipsc-Derived Microglia From The Kolf2.1j Reference Line., Nélio A J Oliveira, Katherine R Lewkowicz, Patricia A Clow, Michael E Ward, Mark R Cookson, William C Skarnes, Justin A Mcdonough

Faculty Research 2025

We present a detailed, xeno-free protocol for the rapid differentiation of human induced pluripotent stem cells (hiPSCs) into microglia using the well-characterized KOLF2.1J reference line. This system employs doxycycline-inducible expression of six transcription factors (6-TF), stably integrated into the CLYBL safe harbor locus, to drive uniform microglial differentiation within two weeks. Adapted from Dräger et al. (1), our protocol includes key optimizations for KOLF2.1J, including culture on Laminin-521 to support xeno-free conditions. The resulting i-Microglia exhibit hallmark features of mature microglia, including expression of P2RY12, loss of the pluripotency marker SSEA4, phagocytic activity, and upregulation of immune markers (e.g., CD80, …


Copyright Accelerationism, Benjamin L.W. Sobel Aug 2025

Copyright Accelerationism, Benjamin L.W. Sobel

Chicago-Kent Law Review

No abstract provided.


Losing The Big Picture: An Argument For Preserving Irpa Rights For Emotional Damages, Stephen Luke Winbery Aug 2025

Losing The Big Picture: An Argument For Preserving Irpa Rights For Emotional Damages, Stephen Luke Winbery

Chicago-Kent Law Review

No abstract provided.


Copyright Re-Alignment: The Growth Of New Works Outside The Copyright System, Edward Lee Aug 2025

Copyright Re-Alignment: The Growth Of New Works Outside The Copyright System, Edward Lee

Chicago-Kent Law Review

No abstract provided.


Win-Win: How To Remove Copyright Obstacles To Ai Training While Ensuring Author Remuneration (And Why The Ai Act Fails To Do The Magic), Martin Senftleben Aug 2025

Win-Win: How To Remove Copyright Obstacles To Ai Training While Ensuring Author Remuneration (And Why The Ai Act Fails To Do The Magic), Martin Senftleben

Chicago-Kent Law Review

No abstract provided.


Temporal Patterns Of Ectopic Pregnancy: Using The Electronic Health Record To Illuminate A Dark Corner In Women's Health, Kirsten Hepburn Aug 2025

Temporal Patterns Of Ectopic Pregnancy: Using The Electronic Health Record To Illuminate A Dark Corner In Women's Health, Kirsten Hepburn

Theses & Dissertations

Ectopic pregnancy remains a significant contributor to pregnancy-related morbidity and mortality, yet little is known about whether its occurrence follows discernible temporal patters that could inform prediction and prevention efforts. This dissertation aimed to explore the temporal characteristics of ectopic pregnancy through three interrelated projects: development of a new theoretical framework, a scoping review of the literature on ectopic pregnancy temporal patterns, and an empirical study using electronic health records data from a ten-year period at a single academic medical center. The Nursing Genomic and epigenomic, Environment, and Microbiome (N-GEM) situation-specific theoretical framework was introduced as a novel nursing theory …


The Characterization Of Per- And Polyfluoroalkyl Substances (Pfas) In Nebraska Drinking Water And Human Health Impacts, Sarah Tucker Aug 2025

The Characterization Of Per- And Polyfluoroalkyl Substances (Pfas) In Nebraska Drinking Water And Human Health Impacts, Sarah Tucker

Theses & Dissertations

Per- and polyfluoroalkyl substances (PFAS) are synthetic compounds that have been detected in water sources of urban and rural environments with evidence of adverse human health effects from exposure. Humans are primarily exposed through ingestion of contaminated water and food. PFAS exposure has been linked to negative multi-system health outcomes (liver, kidneys, cardiovascular, reproductive, and immune). PFAS occur as persistent mixtures in environmental media with decades long consequences to water quality. While national agencies have launched large-scale PFAS water quality monitoring studies, limited data exists for contamination of rural water in Nebraska, especially private wells. The aims of this study …


Symptom Clusters And Their Association With Health-Related Quality Of Life In Pediatric Cancer Survivors After Treatment Completion, Krishtee Napit Aug 2025

Symptom Clusters And Their Association With Health-Related Quality Of Life In Pediatric Cancer Survivors After Treatment Completion, Krishtee Napit

Theses & Dissertations

A critical area of cancer research, symptom management, has evolved from focusing on individual symptoms to recognizing the complexity of co-occurring symptoms, commonly referred to as symptom clusters. However, most studies on pediatric cancer symptom clusters have focused primarily on the treatment phase or long-term survivorship, overlooking the early post-treatment period. This dissertation examines the prevalence of multiple symptoms and symptom clusters in pediatric cancer survivors post-treatment; factors associated with the total number of symptoms and symptom clusters; and the association of the total number of symptoms and symptom clusters with health-related quality of life (HRQoL). We developed and tested …


Josue Sanchez V. Attorney General United States Of America Aug 2025

Josue Sanchez V. Attorney General United States Of America

2025 Decisions

Agency


Allaeldin Elhattab V. Attorney General United States Of America Aug 2025

Allaeldin Elhattab V. Attorney General United States Of America

2025 Decisions

Agency


East Ohio Capital Llc V. City Of Pittsburgh Zoning Board Of Adjustment Aug 2025

East Ohio Capital Llc V. City Of Pittsburgh Zoning Board Of Adjustment

2025 Decisions

USDC for the Western District of Pennsylvania


Pinch: Pipeline-Informed Noise Characterization In Ligo’S Third Observing Run, Zach Yarbrough, Andre Guimaraes, Prathamesh Joshi, Gabriela González, Andrew Valentini Aug 2025

Pinch: Pipeline-Informed Noise Characterization In Ligo’S Third Observing Run, Zach Yarbrough, Andre Guimaraes, Prathamesh Joshi, Gabriela González, Andrew Valentini

Faculty Publications

We present a method to identify and categorize gravitational wave candidate triggers identified by matched filtering gravitational wave searches (pipelines) caused by transient noise (glitches) in gravitational wave detectors using support vector machine (SVM) classifiers. Our approach involves training SVM models on pipeline triggers which occur outside periods of excess noise to distinguish between triggers caused by random noise and those induced by glitches. This method is applied independently to the triggers produced by the GstLAL search pipeline on data from the laser interferometer gravitational-wave observatory Hanford and Livingston observatories during the second half of the O3 observing run. The …


Effectiveness Of Leadership Rounding In Reducing Patient-Related Falls In A Medical-Surgical Unit, Elsie-Solange Mvoueng Nkoi-Mimba Aug 2025

Effectiveness Of Leadership Rounding In Reducing Patient-Related Falls In A Medical-Surgical Unit, Elsie-Solange Mvoueng Nkoi-Mimba

Walden Dissertations and Doctoral Studies

Summary In this Doctor of Nursing Practice (DNP) project, I evaluated whether the project site organization’s implementation of leadership rounding reduced patient falls within a medical-surgical unit. Despite established fall prevention strategies, the unit continued to experience ongoing incidents, prompting the implementation of structured leadership rounding. The practice-focused question assessed changes in fall rates over a 3-month postintervention period compared to the preceding 3 months. A retrospective chart review was conducted from December 2023 to June 2024, excluding March 2024 due to partial implementation. I used descriptive statistics to analyze trends. The average monthly fall rate remained stable at 2.67 …


Structure And Function Of Type 1 Pilus Assembly Machinery In Uropathogenic Escherichia Coli, Ryan Bitter Aug 2025

Structure And Function Of Type 1 Pilus Assembly Machinery In Uropathogenic Escherichia Coli, Ryan Bitter

Arts & Sciences Graduate Student Theses and Dissertations

Gram-negative bacteria produce chaperone-usher pathway (CUP) pili, which are extracellular adhesive protein fibers critical for host-pathogen interactions. An outer-membrane usher protein, together with a periplasmic chaperone, assembles thousands of pilin subunits into a pilus fiber. Each pilus is tipped by an adhesin that mediates host and tissue tropisms by binding to receptors with stereochemical specificity. Type 1 pili expressed by uropathogenic Escherichia coli (UPEC) are essential virulence factors in urinary tract infections (UTIs) and facilitate attachment to mannosylated glycoproteins on bladder epithelial cells. Although type 1 pili have been extensively studied, critical gaps remain in our understanding of the molecular …


Evaluation Of Rheumatic Etiologies Underlying Childhood-Onset Arthritis, Seher Şener, Erdal Atalay, Ezgi̇ Deni̇z Batu, Cansu Ayten Tatar, Özge Başaran, Yelda Bi̇lgi̇ner, Seza Özen Aug 2025

Evaluation Of Rheumatic Etiologies Underlying Childhood-Onset Arthritis, Seher Şener, Erdal Atalay, Ezgi̇ Deni̇z Batu, Cansu Ayten Tatar, Özge Başaran, Yelda Bi̇lgi̇ner, Seza Özen

Turkish Journal of Medical Sciences

Background/aim: Childhood-onset arthritis may result from various rheumatic diseases. This study aimed to systematically evaluate their distribution and characteristics in a large pediatric cohort.

Materials and methods: We retrospectively analyzed all pediatric patients who presented with arthritis to the pediatric rheumatology clinic between January 2000 and January 2023.

Results: A total of 1713 pediatric patients who presented with arthritis were included in this study (median age at diagnosis: 6.8 years; F/M = 1.2). Most of the patients (n = 859, 50.1%) had juvenile idiopathic arthritis (JIA) (especially oligoarticular JIA). Patients with familial Mediterranean fever, comprising 277 individuals (16.2%) presented with …


What Are The Predictors Of Malignancy In Inflammatory Bowel Disease?, Zülal İstemi̇han, Bi̇lger Çavuş, Ali̇ Emre Bardak, Ayşe Merve Kirkoğlu, Cansu Kiziltaş, Rüveyda Si̇lay, İbrahi̇m Volkan Şenkal, Zi̇ya İmanov, Kenan Nuri̇yev, Aynure Rüstemzade, Sezen Genç, Mi̇ne Güllüoğlu, Asli Çi̇fci̇başi Örmeci̇, Kadi̇r Demi̇r, Fati̇h Beşişik, Sabahatti̇n Kaymakoğlu, Fi̇li̇z Akyüz Aug 2025

What Are The Predictors Of Malignancy In Inflammatory Bowel Disease?, Zülal İstemi̇han, Bi̇lger Çavuş, Ali̇ Emre Bardak, Ayşe Merve Kirkoğlu, Cansu Kiziltaş, Rüveyda Si̇lay, İbrahi̇m Volkan Şenkal, Zi̇ya İmanov, Kenan Nuri̇yev, Aynure Rüstemzade, Sezen Genç, Mi̇ne Güllüoğlu, Asli Çi̇fci̇başi Örmeci̇, Kadi̇r Demi̇r, Fati̇h Beşişik, Sabahatti̇n Kaymakoğlu, Fi̇li̇z Akyüz

Turkish Journal of Medical Sciences

Background/aimː This study aims to investigate the prevalence of malignancy in patients with inflammatory bowel disease (IBD) followed up in a tertiary reference center.

Materials and methodsː IBD patients with at least 6 months of follow-up from the gastroenterology clinic between 2000 and 2022 wereevaluated retrospectively in a tertiary center. Patient information was obtained from the patient registration system.

Resultsː There were 697 patients in the study, 320 (45.9%) of these were female. The mean age of the patients at IBD diagnosis was 33.4± 13.1 years. The mean follow-up time was 93.1 ± 64.8 (median 84, IQR (25–75) (36–144)) months. …


Evaluation Of Metabolic Uptake In Gynecological Organs Using Fdg-Pet In Women Diagnosed With Non-Gynecological Malignancies, Funda Atalay, Uğurcan Zorlu, Koray Aslan, Fatma Batak, Tuba Zengi̇n Aksel, Güli̇n Uçmak Aug 2025

Evaluation Of Metabolic Uptake In Gynecological Organs Using Fdg-Pet In Women Diagnosed With Non-Gynecological Malignancies, Funda Atalay, Uğurcan Zorlu, Koray Aslan, Fatma Batak, Tuba Zengi̇n Aksel, Güli̇n Uçmak

Turkish Journal of Medical Sciences

Background/aim: Gynecological malignancies, including those affecting the uterus, cervix, vagina, vulva, and adnexa, pose significant physical and psychosocial burdens. Early detection and effective management of these malignancies are critical for improving outcomes. This study aims to evaluate metabolic uptake patterns in gynecological organs using fluorodeoxyglucose positron emission tomography (FDG-PET) and to analyze their malignancy potential in women with nongynecological cancers.

Materials and methods: A retrospective analysis was conducted on 221 women with nongynecological malignancies who exhibited pathological FDG uptake in gynecological organs on FDG-PET/CT imaging. Lesions were evaluated based on the standardized uptake value maximum (SUVmax), morphological characteristics on contrast-enhanced …


Detection And Quantification Of Microplastics In Cerumen, Bengi̇ Arslan, Yüce İslamoğlu, Ali̇ Sami̇ Berçi̇n, Selen Akbulut, Mehmet Meli̇koğlu Aug 2025

Detection And Quantification Of Microplastics In Cerumen, Bengi̇ Arslan, Yüce İslamoğlu, Ali̇ Sami̇ Berçi̇n, Selen Akbulut, Mehmet Meli̇koğlu

Turkish Journal of Medical Sciences

Background/aim: Microplastics (MPs) are a growing concern due to their pervasive environmental presence and potential environmental and human exposure impacts. Given evidence of systemic MP presence in human tissues and fluids, and the ear canal's environmental exposure, this novel study aimed to identify these particles in human cerumen. Cerumen was collected from the proximal ear canal to minimize potential airborne contamination.

Materials and methods: Cerumen samples were prospectively collected from 12 adult patients (23 patient-derived specimens) and 3 control water samples, following ethical approval and consent. Samples were extracted using sterile instruments, stored in glass, diluted, and filtered through 0.22 …


Are Paraplegic Wheelchair Users Vulnerable To Overuse Syndromes?, Kutay Tezel, Esra Ülgen Kiratlioğlu, Hüseyi̇n Kayadi̇bi̇, İlkay Karabay, Mi̇tat Cebeci̇, Eda Gürçay Aug 2025

Are Paraplegic Wheelchair Users Vulnerable To Overuse Syndromes?, Kutay Tezel, Esra Ülgen Kiratlioğlu, Hüseyi̇n Kayadi̇bi̇, İlkay Karabay, Mi̇tat Cebeci̇, Eda Gürçay

Turkish Journal of Medical Sciences

Background and Aims: The purposes of this study are to determine the frequency of upper extremity overuse syndromes in patients with spinal cord injury (SCI) using manual wheelchairs, to evaluate them clinically and sonographically, and to reveal possible factors that predispose to overuse syndromes.

Materials and methods: A total of 38 traumatic SCI patients who were over 18 years of age and manual wheelchair users were enrolled in this cross-sectional study. The patients were evaluated with clinical and sonographic findings of the wrist, elbow and shoulder joints. Functional capacity, physical ability and symptoms of upper extremity, and quality of …