Digital Commons Network^™

Herp Count 2025, Camryn Gulledge

Graduate Theses/Dissertations

Herp Count 2025 is a process-based project in which I log and document every herp (reptile or amphibian) I encounter in the wild while investigating the realities of human impact on ecosystems. During 2025, I observed 1,406 individual herps, most of which appeared not in remote wilderness but in the compromised margins of human spaces. When I observe them in a littered area, I collect nearby trash and bring it back to my studio to combine it with a detailed drawing of that specific individual. In my Contact series, I use a clean-touch printmaking process that involves a stretched plastic …

Exploring Factors Mediating White-Nose Syndrome In Little Brown Bats, Carly R. Trujillo

Graduate Theses/Dissertations

The little brown bat (Myotis lucifugus) has experienced drastic population declines across North America due to the recent disease white-nose syndrome (WNS). Previous studies have identified putatively adaptive alleles (PAAs) that may give individuals a greater likelihood of survival. However, there could be geographic-specific adaptation, creating different adaptive landscapes. Additionally, there may be energetic trade-offs between disease survival and reproductive output, and it is not clear what the long-term survival outcomes for the species may be as a result. Long-term evolutionary outcomes are unclear because this species has a lifespan exceeding the arrival of WNS and is difficult …

The Effect Of Sex On A-To-I Editing In Skeletal Muscle During Inflammation, Skyler Lee

Graduate Theses/Dissertations

Adenosine-to-inosine (A-to-I) RNA editing is a post-transcriptional mechanism mediated by ADAR enzymes that can alter RNA sequence, protein function, and gene regulation. Because ADAR1 is upregulated during inflammation and plays a critical role in innate immunity, previous studies investigated the effects of acute inflammation on RNA editing in male and female mice. Lipopolysaccharide (LPS) was used to induce inflammation, and RNA editing levels were examined in the heart, brain, and skeletal muscle. While editing levels in the heart and brain remained unchanged, skeletal muscle exhibited tissue- and sex-specific differences in editing. In this thesis, LPS treatment affected selective editing, increasing …

Climate Change In Gilgit-Baltistan: Satellite-Based Land Use/Land Cover Change Detection, Socio-Economic Dimensions, And Adaptation Strategies, Ali Muhammad

Graduate Theses/Dissertations

Climate change is increasingly transforming the cryosphere, hydrology, and human landscape of Gilgit-Baltistan, a highly climate-sensitive mountain region in northern Pakistan. This thesis investigates these transformations through satellite-based land use/land cover (LULC) change detection in four representative tehsils of Gilgit-Baltistan—Ali Abad, Gilgit, Nagar, and Sikander Abad—selected to span a gradient of human pressure and cryospheric exposure within the region. Using summer, cloud-free (< 10%) imagery from USGS Landsat 7 (2000) and Landsat 8 (2025), it conducts a multi-temporal comparison of environmental and socio-spatial change. After atmospheric correction and band compositing, the imagery is classified in ArcGIS Pro into six classes—Water, Barren land, Vegetation, Snow, Glacier, and Built-up—using a Support Vector Machine (SVM) classifier, with Maximum Likelihood Classification and Random Forest also tested but found less suitable for the final workflow. The analysis detects a pronounced reduction in mapped glacier-class area alongside a comparatively stable snow class, together with built-up expansion, while examining how temperature, precipitation, tourism, and population dynamics relate to observed LULC transitions. The results reveal a pattern of cryospheric decline and urban growth, with implications for water availability, ecological stability, hazard exposure, and settlement pressure. By integrating geospatial change detection with climatic and socio-economic interpretation, the thesis moves beyond mapping to explain interacting environmental and human drivers of landscape transformation and provides a reproducible remote-sensing baseline for monitoring land-surface change in heterogeneous mountainous terrain. It recommends integrated water-resource management, climate-resilient land-use planning, watershed and glacier monitoring, and sustainable tourism governance, supporting evidence-based decision-making by the Government of Gilgit-Baltistan and organizations working on climate adaptation, disaster risk reduction, and sustainable regional development.

Student Perspectives Of A Rubric-Based Performance Assessment In A Secondary Large Ensemble Classroom: Fairness, Clarity And Learning, Jeffrey S. Payne

Graduate Theses/Dissertations

The purpose of this study was to investigate student perceptions of a rubric-based performance assessment within a secondary large ensemble music program.  Seventy high school students enrolled in a high school band class completed a rubric-based performance assessment that featured personalized feedback and opportunities for resubmission  Using a mixed-methods approach, 17 students in the class voluntarily participated in a survey, the results of which I used to study my own use of assessment.  The survey consisted of eight Likert-scale questions and four open-response questions which were used alongside data regarding the resubmission rate and teacher documentation of instruction. Results indicated …

Development And Validation Of The Ipip-Ocean: A Hierarchical Facet-Level Measure Of The Big Five, Caleb Niccum

Graduate Theses/Dissertations

This study focused on developing a mid-range, hierarchical, five-factor, 20-facet personality inventory (the IPIP-OCEAN) composed of 100 items drawn from both the IPIP-NEO-300 and the Abridged Big Five Circumplex. Hierarchical confirmatory factor analysis was used to validate the factor structure. Depression and anxiety, measured with the PHQ-9 and GAD-7, were used to further validate the measure through discriminant and convergent validity by examining whether the domains and facets of the IPIP-OCEAN produced findings consistent with those reported for similar scales in prior depression and anxiety research. Numerous factor analyses were conducted on the IPIP-OCEAN dataset (N = 1,058), and a …

In Service Of The State: Foreign Financing, Infrastructure, And Imperialism In Tsarist Russia, Christopher A. Hartwell, Paul Vaaler, Boris Vinogradov

Articles

Russia’s imperialism in the nineteenth century has been far less scrutinized than other episodes of great power colonization, but the Tsar’s expansion into the Caucasus was indeed an ongoing imperial project. The movement of Russian troops and settlers was only feasible with the creation of a large railway network, an undertaking for which the Tsarist regime lacked adequate funding. In response, the regime developed a system of state guarantees and incentives to attract foreign investors looking for higher returns and willing to finance railways serving the imperial project. We illustrate this point with a case study of Paris-based Crédit Lyonnais …

2026-2027, Benjamin N. Cardozo School Of Law

Student Handbooks

No abstract provided.

From Authorization To Loss: A Blockchain Forensic Analysis Of Transaction-Level Mechanisms In Cryptocurrency Airdrop Scams, Chanwoo Shin, Kyung-Shick Choi

International Journal of Cybersecurity Intelligence & Cybercrime

Cryptocurrency airdrop scams have emerged as a rapidly growing form of cyber-enabled financial crime, yet remain underexplored in empirical research. This study examines how transaction-level mechanisms and offender strategies influence variation in monetary loss in airdrop scam incidents. Grounded in Cyber-Routine Activities Theory (Cyber-RAT), the study conceptualizes financial harm as occurring within decentralized environments where users’ online behaviors, particularly transaction authorization, intersect with limited digital capable guardianship. Data were drawn from 112 validated airdrop scam cases reported on Chainabuse.com between January and December 2025. Blockchain forensic analysis using Breadcrumbs was conducted to reconstruct transaction pathways, identify exchange interactions, and detect …

“A Civilised Order”: Political Economy Of Welfare State Development In United States And South Africa, Camden M. Webb

Masters Theses

The welfare state and its development across national contexts in the twentieth century signaled a marked change in the state’s relationship with its citizens. They developed in a structural crisis between two political economy organizations, moving from liberal structures to regulated ones. As the world continues the current ongoing structural crisis out of the neoliberal structure, the future of welfare policy is uncertain. My research presents a Qualitative Comparative Analysis (QCA) using the United States and South Africa as most-different cases to explore the similarities and differences in their national contexts that shaped their welfare state development in the early …

The Disability History Of Brown V. Board Of Education, Britney Wilson

Articles & Chapters

In 1952, two years before the Supreme Court of the United States decided Brown v. Board of Education, Black deaf students in Washington, D.C., who had been prohibited from attending the local school for white deaf students and forced to go to school in Maryland, won the right to be educated in their hometowns in Miller v. Board of Education of District of Columbia. Brown is heralded as one of the most important racial justice cases of all time. It overturned Plessy v. Ferguson's longstanding "separate but equal" mandate and ruled that the segregation of students based on race violates …

University Of Richmond Magazine - Summer 2026

University of Richmond Magazine

No abstract provided.

Black Hole Spectroscopy And Tests Of General Relativity With Gw250114, Jaclyn (Jax) Sanders

Physics Faculty Research and Publications

The binary black hole signal GW250114, the loudest gravitational wave detected to date, offers a unique opportunity to test Einstein’s general relativity (GR) in the high-velocity, strong-gravity regime and probe whether the remnant conforms to the Kerr metric. Upon perturbation, black holes emit a spectrum of damped sinusoids with specific, complex frequencies. Our analysis of the postmerger signal shows that at least two quasinormal modes are required to explain the data, with the most damped remaining statistically significant for about one cycle. We probe the remnant’s Kerr nature by constraining the spectroscopic pattern of the dominant quadrupolar (ℓ=m=2) …

Engineering Mutation Clones In Mammalian Cells With Crispr/Cas9, Zijun Huo, Jian Tu, Rachel Shoemaker, Dung-Fang Lee, Ruiying Zhao

Faculty, Staff and Student Publications

CRISPR, Clustered Regularly Interspaced Short Palindromic Repeat, as a powerful genome engineering system, has been widely accepted and employed in gene editing of a vast range of cell types. Compared to zinc finger nucleases (ZFNs) or transcription activator-like effector nucleases (TALENs), CRISPR shows a less complicated process and higher efficiency. With the development of different CRISPR systems, it can be used not only to knock out a gene but also to make precise modifications, activate or repress target genes with epigenetic modifications, and even for genome wide screening. Here we will describe the procedure of generating a stable cell line …

Host Modulation Therapy In Periodontitis: From Established Therapies To Emerging Technologies, Aonjittra Phanrungsuwan, Jiaqi Huang, Neeraja Dharmaraj, Alejandra Cobos Perez, Omid Veiseh, Simon Young, Chun-Teh Lee

Faculty, Staff and Student Publications

Periodontitis is a biofilm-induced chronic inflammatory disease, characterized by gingival inflammation and alveolar bone loss. According to a national survey, approximately half of the U.S. adults are affected by periodontal disease. To effectively prevent and treat periodontitis, it is essential to address its underlying causes. The primary etiological factors include polymicrobial synergy and dysbiosis of the oral microbiota, and a dysregulated immune response. The standard therapeutic approach, mechanical removal of biofilm through debridement, sometimes demonstrates limited efficacy, particularly in cases of severe periodontitis, which may require adjunctive or additional therapy. Emerging evidence indicates that periodontal tissue destruction is initiated by …

Grading Melanocytic Dysplasia: Updated Histopathologic Criteria, Christopher R Shea, Victor G Prieto, Catherine M Shachaf, Scott R Florell

Faculty, Staff and Student Publications

Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO-C). WHO-C presents a dichotomous classification (high-grade versus low-grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement. The Duke classification is a related approach that provides mostly quantitative histopathologic criteria for dysplastic nevi and gives due weight to architectural features as well as cytology. This paper proposes and illustrates updated criteria for scoring and grading melanocytic dysplasia, incorporating some of the definitions and categories of WHO-C, while refining the quantitative and …

Nsd2 Inhibitors Rewire Chromatin To Treat Lung And Pancreatic Cancers, Jinho Jeong, Simone Hausmann, Hanyang Dong, Kacper Szczepski, Natasha M Flores, Andy Garcia Gonzalez, Liyang Shi, Xiaoyin Lu, Joanna Lempiäinen, Moritz Jakab, Liyong Zeng, Tourkian Chasan, Eric Bareke, Rui Dong, Emma Carlson, Reinnier Padilla, Dylan Husmann, Julia Thompson, Gerry A Shipman, Emily Zahn, Courtney A Barnes, Laiba F Khan, Liz Marie Albertorio-Sáez, Eva Brill, Vishnu Udayakumar Sunita Kumary, Matthew R Marunde, Danielle N Maryanski, Cheryl C Szany, Bryan J Venters, Carolina Lin Windham, Michal Eligiusz Nowakowski, Iwona Czaban, Mariusz Jaremko, Michael-Christopher Keogh, Kang Le, Michael J Soth, Benjamin A Garcia, Łukasz Jaremko, Jacek Majewski, Pawel K Mazur, Or Gozani

Faculty, Staff and Student Publications

NSD2 catalyses the epigenetic modification H3K36me2 (refs. 1,2) and is a candidate convergent downstream effector of oncogenic signalling in diverse malignancies3–5. However, it remains unclear whether the enzymatic activity of NSD2 is therapeutically targetable. Here we characterize a series of clinical-grade small-molecule catalytic NSD2 inhibitors (NSD2i) and show that the pharmacological targeting of NSD2 constitutes an epigenetic dependency with broad therapeutic efficacy in KRAS-driven preclinical cancer models. NSD2i inhibits NSD2 with single-digit nanomolar half-maximal inhibitory concentration potency and high selectivity over related methyltransferases. Structural analyses reveal that the specificity of NSD2i for NSD2 …

Evolving Molecular Subtypes Of Gastric Cancer: From Past Classifications To Present Consensus And Future Directions For Precision Therapy, Ju-Seog Lee

Faculty, Staff and Student Publications

Gastric cancer is a biologically heterogeneous disease. The advent of high-throughput multi-omic technologies has revolutionized our understanding of gastric cancer by deconstructing this heterogeneous entity into distinct and more homogeneous molecular subtypes. Early classifications based on gene expression, methylation, and histology have laid the groundwork for multi-omic frameworks proposed by The Cancer Genome Atlas and Asian Cancer Research Group, which established the foundation of modern molecular taxonomy. Subsequent integrative efforts, particularly the Consensus Genomic Subtypes (Super 6) model, have unified this collected information into clinically relevant subtypes that bridge prognostic stratification with treatment strategies. Established biomarkers such as human epidermal …

Prickle4 Drives Microenvironmental Remodeling And Resistance To Parp Inhibition In Idh-Mutant Glioma, Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T Huse, Bo Chen, Timothy A Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang

Faculty, Staff and Student Publications

Mutations in isocitrate dehydrogenase (IDH) genes sensitize gliomas to PARP inhibition (PARPi) by inducing epigenetic reprogramming of DNA damage repair circuits. However, tumors treated with PARPi eventually relapse despite initial responsiveness. In this study, it is demonstrated that the anti-angiogenic agent lenvatinib synergizes effectively with PARPi, resulting in substantial tumor regression and significantly extended survival. Genomic analysis of tumors reveals that PARPi induces widespread transcriptomic changes that are predominantly pro-inflammatory, thereby promoting tumor angiogenesis. Prickle4, a planar cell polarity protein, is identified as a critical mediator of PARPi-induced neovascularization. Targeting Prickle4 effectively overcomes PARPi resistance in these tumors. Collectively, these …

Clinical And Molecular Characteristics Of Patients With Young-Onset And Average-Onset Pancreatic Adenocarcinoma, Adriana C Gamboa, Kever A Lewis, Laura R Prakash, Zhouxuan Li, Wei Qiao, Dan Zhao, Mark W Hurd, Mahmoud Yousef, Naruhiko Ikoma, Michael P Kim, Jeffrey E Lee, Jessica E Maxwell, Ching-Wei D Tzeng, Matthew H G Katz, Rebecca A Snyder

Faculty, Staff and Student Publications

Purpose: The incidence of young-onset pancreatic cancer (YO-PC) has risen over the past two decades, yet its molecular characteristics and long-term outcomes remain poorly defined.

Methods: We retrospectively evaluated patients with PC treated at a tertiary referral center from 2016 to 2022 who had available molecular data. Patients were classified as YO-PC (≤50 years) or average-onset PC (AO-PC, >50 years). A subset analysis examined outcomes in those who underwent curative-intent pancreatectomy. Primary end points included overall survival (OS) and recurrence-free survival (RFS).

Results: Among 511 patients, 10.9% had YO-PC (n = 56; median age 44 years). Patients with YO-PC more …

Endogenous Processes Underlying Clock-Like Mutational Signatures, Teresa Druck, Rami I Aqeilan, C Marcelo Aldaz, Nicola Zanesi, Kay Huebner

Faculty, Staff and Student Publications

Wellcome Trust scientists have shown that “mutational signatures” in specific nucleotide contexts accumulate in genomes of mammalian tissues, providing clues to underlying causes of specific signatures. Analysis of cancer genomes has identified more than 50 single‐base substitution (SBS) signatures, with SBS1, SBS5, and SBS40 linked to aging and present in normal tissues. SBS1 results from cytosine demethylation, whereas SBS5 and SBS40 arise from unknown endogenous mechanisms. We hypothesized that loss of fragile‐site genes drives these two signatures. FHIT, located at FRA3B, is frequently deleted in cancers, and Fhit‐deficient mouse tissues exhibit a mutation profile resembling human SBS5. Data mining of …

A Constraint-Based Approach To Developing Melodic Improvisational Skills In Intermediate Jazz Piano Students, Alton Xian Rong Wong

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examines the pedagogical value of a constraint-based approach in helping students develop improvisational fluency and coherence by facilitating audiation. Although there are pedagogical texts on jazz improvisation that incorporate exercises shaped by constraint-based thinking, there is neither a systematic framework for their application with students of varying levels and musical backgrounds, nor a clear explanation of their pedagogical purpose. This research investigates how constraint-based pedagogy, through the lens of rhythmic, harmonic, and melodic parameters, can be applied independently or collectively to support the development of improvisational fluency in intermediate level jazz piano improvisers. It argues that musical constraints …

Investigation Of Succinylated Zwitterionic Polyethylenimine/Dna Complexes: Performance In Serum, Internalization, And Intracellular Fate, Levi Lampe

Theses and Dissertations--Chemical and Materials Engineering

Gene therapy has promised to revolutionize medicine since the earliest clinical trials, but a lack of delivery methods that are both safe and efficient has hampered progress. Gene therapy with viral vectors is effective at delivering nucleic acids to cells, but is associated with dangerous immunogenic responses and cancer-causing insertions into the genome. Viral vectors are also among the most prohibitively costly therapeutics in medicine. Polymeric vectors avoid these dangers and are made from inexpensive, off-the- shelf materials, but have been hindered by poor efficiency compared to viral vectors.

A benchmark polymer for in vitro nucleic acid delivery has been …

The Impact Of War On The Value-Legal Aspects Of State-Confessional Relations In Ukraine, Tetiana Havryliuk, Oleg Buchma, Yulia Bohdan, Anna Hud

Occasional Papers on Religion in Eastern Europe

This article analyzes the latest developments in state-confessional relations in Ukraine that have formed as a result of transformations in the current legislation on religion and religious activity. These transformations were caused by the war of the Russian state against Ukraine, which actively uses religion for propaganda purposes. Spiritual values have become an important element of this propaganda. As demonstrated in the article, they contain a motivating component and therefore play a crucial role in transforming reality. The manipulation of values allows for situations where a tragic war is declared “sacred” and even blessed. The article shows that the amendments …

Religious Radio Broadcasting In Ukraine In The Context Of Digital Mediatisation And Social Transformation, Oleh Sokolovskyi, Olena Yurchuk

Occasional Papers on Religion in Eastern Europe

The study carries out a religious studies analysis of contemporary forms of spiritual communication implemented through audio and digital media platforms. The work highlights the particular features of organizing religious broadcasting under conditions of transformation of the information space, when traditional models of transmitting doctrine become integrated into new technological formats. Mechanisms of the formation of religious identity, ways of maintaining spiritual continuity, and strategies of interaction between religious institutions and their audiences are examined. An analysis is conducted of the structures that ensure access to spiritual content, including forms of catechetical communication, mentoring practices, and models of pastoral support …

The Cross And The Flag: Papal Diplomacy And John Paul Ii’S Struggle Against The Tyranny Of The Possible: A Review, John Grondelski

Occasional Papers on Religion in Eastern Europe

A review of Lebui, John Tanyi Nquah. The Cross and the Flag: Papal Diplomacy and John Paul II’s Struggle Against the Tyranny of the Possible. South Bend, Indiana: St. Augustine’s Press, 2024. Pp. xxvi + 322. PB, $30. ISBN 978-1-58731-143-7.

Eurasianism As The Ideological Foundation Of Putin's Russia: Protestant Dimensions., Pavlo Pavlenko

Occasional Papers on Religion in Eastern Europe

This article explores the ideological foundations of contemporary Putinist Russia, identifying Eurasianism as a primary socio-philosophical and geopolitical doctrine driving the Kremlin's imperial ambitions. The author traces the evolution of Eurasianism from its origins in "White émigré" circles to its current role as a conceptual bedrock for Russian fascism. A comparative analysis is provided between Eurasianism and the "Russian World" (Russkiy Mir) doctrine, highlighting their distinct approaches to ethnocentrism and continental unity. A significant portion of the study is dedicated to the "Eurasianization" of Protestant denominations within the Russian Federation, illustrating how these communities have been instrumentalized by the state …

The Reconfiguration Of Institutional Trust In The Church In Ukraine During The Full-Scale Russian–Ukrainian War, Nataliia Ishchuk

Occasional Papers on Religion in Eastern Europe

The article analyzes the transformation of institutional trust in the Church in Ukraine under the conditions of the full-scale Russian–Ukrainian war. The phenomenon of trust is interpreted as an interdisciplinary concept that makes it possible to combine theological, anthropological, and social approaches to its comprehension. Trust in God and trust in the Church belong to different levels of religious experience: the former has an existential character, while the latter functions as a form of institutional legitimacy. Based on sociological survey data from the Kyiv International Institute of Sociology (KIIS) and the Razumkov Centre, it is demonstrated that throughout all the …

The Transformation Of Traditional And Islamic Values Of Kazakhstani Youth In The Context Of Globalization, Nurgul Kabylbayeva, Kalimash Begalinova, Mohd Roslan Bin Mohd Nor

Occasional Papers on Religion in Eastern Europe

This article provides a comprehensive analysis of the impact of globalization processes on the transformation of traditional and Islamic values among Kazakhstani youth. In the context of contemporary globalization, the expansion of the information space, intensified cultural interaction, and the spread of Western lifestyles significantly influence young people’s worldview and value orientations. The study examines how traditional values inherent in Kazakhstani society and the spiritual and cultural foundations of Islam are being transformed in the consciousness of youth. Particular attention is paid to the emergence of new value models under the influence of globalization and their impact on national identity …

The Response Of Diaspora And Religious Institutions On The Refugee Crisis: Case Study Of The Republic Of Croatia, Galyna Sagan Dr., Tetiana Kostiuk Dr.

Occasional Papers on Religion in Eastern Europe

This article is dedicated to the multifaceted support that Ukrainian diaspora and Catholic organizations in the Republic of Croatia have been providing to Ukrainian refugees since the full-scale Russian invasion on February 24, 2022. The study details the systemic response of such key religious institutions as the Diocese of Križevci, Caritas and the Jesuit Refugee Service (JRS). Particular attention is paid to integration initiatives, like educational programs developed by the Catholic University of Croatia (HKS), and the provision of spiritual and pastoral care, which remains the unique prerogative of the Church. The study emphasizes coordination between ecclesiastical and state …