Digital Commons Network^™

Targeting Il-1 Signaling In Recessive Dystrophic Epidermolysis Bullosa: Improved Survival And Pathogenesis In Rdeb Mouse Model, Rahim Hirani

NYMC Student Theses and Dissertations

Recessive dystrophic epidermolysis bullosa (RDEB) is a devastating inherited blistering disorder caused by biallelic mutations in COL7A1, resulting in deficiency of type VII collagen (C7) and loss of dermal–epidermal adhesion. Beyond mechanical fragility, RDEB is characterized by chronic inflammation, progressive fibrosis, impaired wound healing, severe pain, and an exceptionally high risk of aggressive cutaneous squamous cell carcinoma. Emerging transcriptomic and cytokine profiling studies have identified interleukin-1 alpha (IL-1α) as a dominant and temporally upstream inflammatory mediator in RDEB skin. The central hypothesis of this dissertation is that IL-1α signaling functions as a key initiator and amplifier of inflammation-driven pathology …

Holographic Photopolymerizable Glass: Enhancing Exposure Sensitivity By Tailoring Photoinitiating Systems Based On Bodipy Dyes, Tatsiana Mikulchyk, Aimee Sheehan, Metodej Dvoracek, Izabela Naydenova, Mikhail Filatov

Research Outputs: 2025-Present

The photoinitiating system (PIS) is a key component of holographic materials which needs to be carefully selected and optimized to achieve efficient photopolymerization and, as a result, highly efficient holographic structures. Recently, boron dipyrromethene (BODIPY) dyes have been introduced as a new class of photosensitizers for holographic materials, including photopolymerizable glass, which is characterized by excellent environmental stability. Here, we present a study of the holographic recording capability of the photopolymerizable glass, where PIS was optimized using two approaches: 1) adding a second co-initiator, diphenyl iodonium hexafluorophosphate (DPIHFP) and 2) exploring a range of BODIPY structures, such as anthracene- and …

Shu World Review- March 16th 2026, Diplolab, Seton Hall University

SHU World Review

No abstract provided.

Vision-Language System Using Open-Source Llms For Consent And Instruction Gestures In Medical Interpreter Robots, Thanh Tung Ngo, Emma Murphy, Robert J. Ross

Research Outputs: 2025-Present

Effective communication is vital in healthcare, especially across language barriers, where non-verbal cues and gestures are critical. This paper presents a privacy-preserving vision-language framework for medical interpreter robots that detects specific speech acts (consent and instruction) and generates corresponding robotic gestures. Built on locally deployed open-source models, the system utilizes a Large Language Model (LLM) with few-shot prompting for intent detection. We also introduce a novel dataset of clinical conversations annotated for speech acts and paired with gesture clips. Our identification module achieved 0.90 accuracy, 0.93 weighted precision, and a 0.91 weighted F1-Score. Our approach significantly improves computational efficiency and, …

Measured Results In Georgia's Kenny A. Foster Care Class Action: A Framework For Assessing The Strategic Effectiveness Of Institutional Reform Litigation, Melissa D. Carter, Christopher G. Hempfling

Child and Family Law Journal

No abstract provided.

Involving Interpol: Interpol’S Meddling In International Parental Kidnapping And International Custody Dispute Cases Through Red And Yellow Notices, Chandler Gallucci

Child and Family Law Journal

As the world grows more interconnected through globalization, the opportunity for international parental kidnapping has increased. International parental kidnapping occurs when a parent or guardian wrongfully removes and retains a child from their habitual residency, even with the existence of a custody agreement. This article examines the role of the International Criminal Police Organization (“Interpol”) and how their use of Red and Yellow Notices can meddle in international custody disputes. Interpol consists of 196 member states, each of which is connected through Interpol’s database. Interpol links local law enforcement agencies in each of the member states. A Red Notice is …

Gender Ideology Curriculum In Florida Schools: Parental Rights And Educator Strain, Kimberly Mack

Child and Family Law Journal

No abstract provided.

On The Generality Of Ground, Hannah M. Kunkel

Undergraduate Honors Theses

It is widely held that true grounding claims are general. That is, individual grounding facts are subsumable under general patterns or principles of ground. In this paper, I advocate a novel position in the theory of ground on which particular grounding facts do not generalize to yield patterns of ground. This is not an argument for grounding pluralism, but is analogous to particularist views in metaethics which hold that moral principles are not general, but particular. If true, particularism about ground dissolves a serious challenge to the theory of ground, Louis deRosset's connection problem for non-reductivism. However, rejecting the generality …

The Story Of Belonging: A Rhetorical Analysis Of Transformative Storytelling As A Catalyst For Belonging, Kennedy Kleinman

Undergraduate Honors Theses

This thesis examines how transformative storytelling functions as a catalyst for belonging within institutional contexts, focusing on Brigham Young University (BYU). While institutions increasingly prioritize belonging through policies and programs, many students continue to experience isolation, loneliness, and belonging uncertainty. This project argues that storytelling addresses this gap by providing students with opportunities to participate in their own belonging and contribute to feelings of belonging for other students. This study analyzes student stories developed in structured workshops and shared at BYU campus StorySLAM events. Stories are evaluated for their use of four rhetorical tactics: counter-narrative, bridge-building between ingroups and outgroups, …

From The Pulpit To The Polls: How Religiosity And Gender Affect Political Ambition In Utah, Sydnee Beck

Undergraduate Honors Theses

What role does religiosity play in political ambition for men and women, especially for members of the Church of Jesus Christ of Latter-day Saints in Utah? Research on political ambition and gender has not typically focused on religiosity, but the few researchers that have studied it focus on a metric called “Biblical literalism” (Cassese and Holman 2016). I agree with research claiming that religiosity effect on political ambition is gendered, but take a different approach in crafting a religion-based relationally embedded model of political ambition, specifically in the Church of Jesus Christ of Latter-day Saints (Carroll and Sanbonmatsu 2013). Female …

Innovating For Access: Ai-Enhanced Triage & Intake For Legal Services Organizations, Heidi Behnke

Duke Center on Law & Technology

Artificial intelligence (AI) offers opportunities to meaningfully narrow the access to justice gap by improving the ability of Legal Services Organizations (LSOs) to connect individuals with pro se resources and more effectively connect with individuals who could not otherwise advocate for themselves. Some LSO early adopters have already developed or are in the process of developing such tools. Others are unsure where or how to start.

The results of semi-structured interviews of LSO staff, technology vendors, and leaders/experts in fall 2025 provide information that may assist LSOs in responsibly integrating AI-tools into their triage and intake systems. This paper includes …

Ai Dependency Vs. Doctoral Identity: How Generative Ai Is Challenging The Development Of Independent Scholarly Thinking In Doctoral Students, Valerie A. Storey

All Faculty and Staff Scholarship

The rise of Generative Artificial Intelligence (GenAI) in higher education has altered the conditions under which doctoral students learn, research, and develop as scholars. Although doctoral student use of GenAI has accelerated rapidly, institutional frameworks for responsible and developmentally appropriate use have not kept pace. This paper examines a central paradox in doctoral education: the same tools that enhance research productivity may also weaken intellectual independence when used without guidance. Using a critical review methodology, the study synthesizes 47 sources on doctoral education, GenAI use, policy, and epistemic development. Three interconnected dimensions of risk emerged from the analysis: critical thinking …

Masthead & Table Of Contents, Vol. 104, No. 3

Nebraska Law Review

No abstract provided.

Robot Wingman: Using Ai To Assess An Employment Termination, Henry H. Perritt Jr.

Nebraska Law Review

Four major generative AI engines—DeepSeek, Claude, ChatGPT, and Grok—are useful legal analysis tools for employment law practitioners. This Article presents the results of an experiment in which a transcript of a hypothetical client interview involving potential disability discrimination, retaliation, and wrongful termination claims was submitted to each AI system. The accompanying prompts requested identification and assessment of viable legal theories. The experiment demonstrates that contemporary generative AI performs sophisticated legal analysis comparable to experienced associates, correctly identifying major employment law claims including ADA violations, Title VII discrimination, OSHA retaliation, FMLA interference, and workers’ compensation retaliation. All four engines successfully spotted …

Sticky Science In Court, H. A. Spitzer

Nebraska Law Review

Litigation routinely employs scientific evidence to aid judicial fact-finding and decision-making. This is especially important in areas like family law, where legal standards—such as the best interests of the child—often depend in part on scientific findings. Yet the legal system’s gatekeeping doctrines (Frye, Daubert, and Federal Rule of Evidence 702) apply primarily to expert testimony, leaving other pathways through which scientific evidence reaches courts largely unchecked. These other pathways include citations in briefs and opinions to non-peer-reviewed or non-scientific sources such as law reviews, treatises, and self-published materials, which often become outdated and are not well positioned …

Let Them All Grow: Protecting Nebraska's Intersex Youth From Medical Intervention, Jori Peters

Nebraska Law Review

The Nebraska Legislature passed the Let Them Grow Act on May 22, 2023, which prohibits minors from receiving gender-affirming care in Nebraska. This Note argues that the Act violates the Equal Protection Clause of the Fourteenth Amendment because it exempts intersex children—those born with ambiguous sex characteristics—from protections against unnecessary, irreversible, and nonconsensual medical procedures, while the Act protects those born with clearly male and female sex characteristics. This Note clarifies the distinction between the issues faced by intersex individuals and transgender individuals, and highlights the psychological and physical harms of early sex assignment surgeries. Further, this Note outlines the …

Carson V. Makin: Ending The Status-Use Distinction And Building A Foundation For The Emergence Of Catholic Charter Schools, Tyler Lyon

Nebraska Law Review

Over the course of its history, the United States has wrestled with a wide variety of issues that have tested the tension between the Establishment and Free Exercise clauses of the First Amendment. One such issue involves the extent to which religious schools can access public funds, which was addressed by the proposal of the Blaine Amendment on a national scale in 1875. The Blaine Amendment was intended to prevent religious groups from accessing public funds, and although it did not pass on a national level, it was adopted by many states.

However, some recent United States Supreme Court cases …

On Sovereignty, Outer Space, And Taxation, Erika I. Scuderi

Nebraska Law Review

This Article offers a comprehensive framework for States’ taxing powers in outer space. Beginning with an analysis of the legal status of airspace and outer space, the study addresses the taxation of commercial space activities, where traditional fiscal approaches of residence-based and source-based taxation break down. The discussion ultimately centers on Article VIII of the Outer Space Treaty, on which basis the present Article proposes the “Tax Jurisdiction by Registration Principle,” arguing that the act of registering a space object provides a legal basis for taxing income derived from its use. In doing so, the Article provides for a potential …

Ndls Communicator: Week Of 03.16.26, Notre Dame Law School

NDLS Communicator

The Latest News

• U.S. Supreme Court Justice Clarence Thomas Reflects on Law, Faith, and Judicial Responsibility at Notre Dame Law School
• Notre Dame Law School Delegation Visits Insper in São Paulo, Brazil for Joint Faculty Workshop and Scholarly Exchange
• Notre Dame Law School continues exchange partnership with Ukrainian Catholic University

Alumni News

• Kyle Sommer '09 J.D.

Student News

• J.S.D. candidate Perla Khattar

Faculty Briefs

• Ashley Sanchez
• Derek Muller
• Emily Bremer
• Paul Miller
• Brett Cavanaugh
• Paolo Carozza
• Jimmy Gurulé
• Mary Ellen O'Connell
• A.J. Bellia
• Patrick Corrigan
• Daniel Slate & Paolo Carozza
• Vincent Phillip Muñoz
• Lloyd Mayer

ND Law in the News …

An Exploration Into Network Analyses Of Motor Behavior, Brain-Computer Interface Control, Arousal States, And An Ischemic Lesion Model, Shashank Anand

McKelvey School of Engineering Graduate Student Theses & Dissertations

Network-level modelling of neural function incorporates activity in specific brain regions along with a measure of the interactions between these regions (“connectivity”). Connectivity can be assessed through several means, for example through tractography (structural connectivity) or correlated temporal evolution of neural activity (functional connectivity). These analyses have provided valuable insight into several aspects of brain function, such as top-down control, memory, and navigation. This work focuses on studying neural activity within and between several brain regions across different brain states: namely, during motor actions, sensory perception, brain-computer interface engagement, task-free fluctuations in arousal state, and ischemic injury. High gamma (70-170 …

Exploring The Interplay Of Plastic Hinge Behavior And Soil-Structure Interaction In Frame Structures: Analytical Study, Mouhammed J. Lafta, Mohammed J. Hamood, Qais A. Hasan, Mohammed Y. Fattah

Engineering and Technology Journal

This paper presents a critical synthesis of research on the combined influence of plastic hinge behavior and soil–structure interaction (SSI) on the seismic response of frame structures. Unlike prior reviews that treat these topics separately, the study integrates experimental and numerical evidence to identify how SSI alters hinge formation, drift demand, and energy dissipation, and how hinge modeling assumptions affect soil–foundation response. The reviewed literature (2010–2022) shows a clear growth in publications over time and a dominant reliance on analytical and numerical investigations relative to purely experimental work. A quantitative categorization of the surveyed studies indicates that modeling-focused approaches represent …

Fulfilling Higher Education’S Responsibility To Students And Democracy In A Challenging Political Environment, Abraham Goldberg, Dena Pastor, Kayla Dixon

International Journal on Responsibility

The American Association of Colleges and Universities and more than 70 higher education organizations have expressed their shared commitment to making civic inquiry and democratic engagement central to undergraduate education. A framework emphasizing the development of skills to address public issues through courses and practical experiences accompanied their prominent call. Yet, campuses currently are facing increases in educational gag orders and institutional policies aimed at limiting discussion of DEI topics and political protests. Although attacks on free speech would seem to conflict with efforts to prepare students for democracy, there has been little scholarly attention on what students know about …

Nashville Versus Hollywood: Bridgeport Music's Existential Threat To Live Music Albums, W. Kirk Wolff

Florida Entertainment and Sports Law Review

The Sixth Circuit’s decision in Bridgeport Music, Inc. v. Dimension Films, which eliminated the de minimis exception for sound recording copyrights, has transformed copyright law into a potential weapon for suppressing artistic expression. By adopting a rigid per se infringement standard, the decision empowers bad actors to exploit copyright law against live music recordings, a uniquely vulnerable and culturally significant medium. Under this standard, even the inadvertent inclusion of an imperceptible sound fragment in a live recording—such as a stray copyrighted ringtone or background music at a festival—constitutes actionable infringement, creating significant legal risks for artists and producers. While …

From Mods To Multiplayer: Strategies For Protecting The Video Game Industry From Section 230 Reform, Sophia Simeoni

Florida Entertainment and Sports Law Review

Section 230 of the Communications Decency Act of 1996 has long shielded online platforms from liability for the actions of their users. As calls for its repeal or reform grow louder across the political spectrum, debate has largely centered on social media; however, the video game industry—a significant yet often-overlooked stakeholder in this discourse—also depends heavily on Section 230 protections. From multiplayer servers to online platforms such as Steam, Twitch, and Discord, this Note examines the crucial role Section 230 plays in sustaining the video game ecosystem. It argues that repealing or significantly reforming Section 230 without accounting for the …

New Flames, Old Irons: A Striking Analysis Of Florida's Gaming Compact With The Seminole Tribe, Zen Rizzuto-Flancbaum

Florida Entertainment and Sports Law Review

This Comment analyzes Florida’s gaming compact (the Compact) with the Seminole Tribe, focusing on the legality of allowing online sports betting under the Indian Gaming Regulatory Act (IGRA). The Compact permits the Seminole Tribe to offer statewide online sports betting by “deeming” all bets placed in Florida as occurring on tribal lands, where the Seminole betting servers are located. This Comment argues that such an interpretation stretches the plain meaning of “Indian lands” in IGRA, which traditionally refers to physical land within reservations. Notably, the Ninth Circuit and the D.C. Circuit have seemingly contradictory opinions on this issue. This Comment …

The Fair Use Doctrine In Contemporary Journalism, Carly Ryan

Florida Entertainment and Sports Law Review

Although section 107 of the Copyright Act specifies that “news reporting” is one of the uses of a copyrighted work that may be fair, the current application of the fair use doctrine poses unique difficulties for journalism defendants. This Article argues for several changes in fair use analysis to make the doctrine flexible for journalism defendants. This Article also argues that these changes are necessary to keep the Copyright Act in balance with the First Amendment.

Sheikh Ḥilu: A Crusader Structure And Additional Remains From The Iron Age And Late Ottoman Period, Yoav Arbel, ‘Abed A-Salam Sa‘Id

Qadum: Journal of Excavation Reports from Israel

Excavations at the site of Sheikh Ḥilu in Ḥadera revealed the remains of a possible manor house or farm dating from the Crusader period. The partially exposed two-phase complex is a rare example of a settlement from this period in the Sharon plain. Careful planning and relatively high construction quality attest to its significance; however, apart from its solid architecture, there is no evidence of fortification. The site underwent a non-violent abandonment at the end of the Crusader period, after which it was temporarily settled by squatters. In the late Ottoman period and the early twentieth century, this was the …

Fragmented Responses: Variability In Law Enforcement And Prosecutorial Approaches To Sexual Assault Cases, Veronica Gonzalez

Qualitative Criminology (QC)

"Sexual assault (SA) remains a pervasive issue in the United States, marked by low reporting rates, inconsistent investigations, and limited convictions. In response, researchers and practitioners have promoted a range of best practices aimed at improving law enforcement and prosecutorial responses. This qualitative study draws on interviews with 13 law enforcement agencies and 12 prosecutors' offices to explore how recommended practices—such as victim advocacy, specialized units, interagency collaboration, and case reviews—are interpreted and operationalized in the field. Findings reveal substantial variability, shaped not only by resource availability but also by leadership priorities, organizational culture, and the ambiguity of guidance documents. …

Aging On Parole: A Thematic Analysis Of The Parole Officer’S Perspective, Angela Murolo

Qualitative Criminology (QC)

"A growing proportion of people leaving prison are over 50 years old and will live at least temporarily under the supervision of a parole officer. While recidivism rates are lower for older people, there are physical, mental, and societal challenges that accompany advancing age that make successful reentry and reintegration a challenging experience compared to their younger counterparts. This presents novel challenges for parole officers who are tasked with supervising and counseling elderly people on parole. Surveys containing closed and open-ended questions were administered to N=25 parole officers to understand the differences in working with, counseling, and supervising older and …

The Bankruptcy Revolving Door, Belisa Pang

Articles

The American consumer bankruptcy system is a costly regime with profound societal implications. Between 2008 and 2023, consumers filed 13.8 million bankruptcy cases across the ninety-four federal bankruptcy districts in the United States, generating over $4 billion in court filing fees alone. When accounting for attorney fees, trustee expenses, creditor costs, and broader economic externalities—such as increased interest rates borne by other consumers—the total financial impact easily reaches tens of billions, if not hundreds of billions, of dollars.

Against that backdrop, this study uncovers a startling phenomenon: nearly 46% of the consumers who filed bankruptcy in 2023 were repeat filers, …