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Articles 13441 - 13470 of 1194476
Full-Text Articles in Entire DC Network
Confronting Domestic Violence, Jessica Miles
Confronting Domestic Violence, Jessica Miles
Elisabeth Haub School of Law Faculty Publications
The Supreme Court's modern Confrontation Clause jurisprudence has created a morass with profound consequences for domestic violence prosecutions. Prior Confrontation Clause scholarship from a domestic violence survivor advocacy perspective has favored prosecutions regardless of survivors' wishes or participation. This Article takes a different view based on a growing body of scholarship arguing that carceral approaches have failed to reduce rates of domestic violence and resulted in negative collateral consequences for many survivors, particularly those from historically marginalized groups. It makes a novel contribution by drawing on the Confrontation Clause as a mechanism to discourage domestic violence prosecutions when not desired …
Efficient In Vivo Pharmacological Inhibition Of Δfosb, An Ap-1 Transcription Factor, In The Brain, Sean Mcneme, Anil Kumar, Yun Young Yim, Brandon W Hughes, Corey St Romain, Yi Li, Ashwani Kumar, Qichao Bao, Molly Estill, Shanghua Fan, Nadeen Takatka, Earnest P Chen, Matthew Rivera, Haiying Chen, Alfred J Robison, Mischa Machius, Stephen J Haggarty, Jeannie Chin, Eric J Nestler, Jia Zhou, Gabby Rudenko
Efficient In Vivo Pharmacological Inhibition Of Δfosb, An Ap-1 Transcription Factor, In The Brain, Sean Mcneme, Anil Kumar, Yun Young Yim, Brandon W Hughes, Corey St Romain, Yi Li, Ashwani Kumar, Qichao Bao, Molly Estill, Shanghua Fan, Nadeen Takatka, Earnest P Chen, Matthew Rivera, Haiying Chen, Alfred J Robison, Mischa Machius, Stephen J Haggarty, Jeannie Chin, Eric J Nestler, Jia Zhou, Gabby Rudenko
Faculty, Staff and Students Publications
ΔFOSB, an unusually stable member of the AP-1 family of transcription factors, mediates long-term maladaptations that play a key role in the pathogenesis of drug addiction, cognitive decline, dyskinesia, and several other chronic neurological and psychiatric conditions. We have recently identified that 2-phenoxybenzenesulfonic acid-containing compounds disrupt the binding of ΔFOSB to DNA in vitro in cell-based assays, and one such compound, JPC0661, disrupts ΔFOSB binding to genomic DNA in vivo in the mouse brain with partial efficiency. JPC0661 binds to a groove outside of the DNA-binding cleft of the ΔFOSB/JUND bZIP heterodimer in a cocrystal structure. Here, we generated a …
The American Asthma Patient, Ana Santos Rutschman
The American Asthma Patient, Ana Santos Rutschman
Faculty Publications
On average, one in twelve people in America have asthma, and ten patients die from asthma every day. A largely manageable disease, asthma nonetheless takes a tremendous toll on patients in the United States.
For almost two decades, these patients have seen the cost of asthma medication rise exponentially, even though some of the most commonly prescribed treatments have existed since the mid-twentieth century. Today, one in six asthma patients reports skipping, delaying or foregoing treatment for financial reasons.
This article presents a case study on a specific product—asthma inhalers—as a lens through which to examine the origins of the …
Long-Term Effect Of Ammonia- And Water-Based Silver Fluoride On Dentin Collagen Matrix, Merve Uctasli, Roda Seseogullari-Dirihan, Thiago Henrique Scarabello Stape, Mustafa Murat Mutluay, Arzu Tezvergil-Mutluay
Long-Term Effect Of Ammonia- And Water-Based Silver Fluoride On Dentin Collagen Matrix, Merve Uctasli, Roda Seseogullari-Dirihan, Thiago Henrique Scarabello Stape, Mustafa Murat Mutluay, Arzu Tezvergil-Mutluay
School of Dentistry Faculty Research and Publications
Objective
To evaluate the long-term effect of ammonia- and water-based silver fluoride treatments on the degradation of the dentin collagen matrix.
Methods
Dentin beams (0.3x3x7mm) were demineralized (10 % H3PO4), rinsed and randomly distributed into six groups. Groups (n = 10 beams/group) were treated with (1) ammonia-based silver fluoride = SDF; (2) SDF + potassium iodide = KI (3) water-based silver fluoride = SF (4) SF + KI (5) KI (6) untreated demineralized dentin beams served as control. Following treatments, dry mass, modulus of elasticity and enzymatic activity were assessed. Dentin beams were incubated in calcium- …
Predictors Of Total Hip Arthroplasty Among Patients With Chronic Comorbidities: A Multivariate Analysis Of A Medically Underserved Region, Blake C. Martin, Manoj Peiris
Predictors Of Total Hip Arthroplasty Among Patients With Chronic Comorbidities: A Multivariate Analysis Of A Medically Underserved Region, Blake C. Martin, Manoj Peiris
School of Medicine Publications
Background
THA is a common orthopedic procedure that is expected to increase in the coming years. Obesity and osteoarthritis are major factors that increase the risk of individuals requiring THA. The Rio Grande Valley (RGV) is a distinctive health professional shortage area with high rates of obesity, arthritis, and diabetes. This study aims to examine the relationship between chronic medical conditions and the need for THA in this at-risk, medically underserved population.
Methods
This investigation employed a retrospective chart review encompassing patient records from January 1, 2018, through January 1, 2025, using the University of Texas Rio Grande Valley electronic …
Roadmap On Artificial Intelligence-Augmented Additive Manufacturing, Ali Zolfagharian, Liuchao Jin, Qi Ge, Wei-Hsin Liao, Andrés Díaz Lantada, Francisco Franco Martínez, Tianyu Zhang, Tao Liu, Charlie C.L. Wang, Mohammad Hossein Mosallanejad, Reza Ghanavati, Abdollah Saboori, Alejandro De Blas De Miguel, William Solórzano-Requejo, Yi Cai, Xiangyang Dong, Huangyi Qu, Najmeh Samadiani, Guangyan Huang, Austin Downey, Yanzhou Fu, Lang Yuan
Roadmap On Artificial Intelligence-Augmented Additive Manufacturing, Ali Zolfagharian, Liuchao Jin, Qi Ge, Wei-Hsin Liao, Andrés Díaz Lantada, Francisco Franco Martínez, Tianyu Zhang, Tao Liu, Charlie C.L. Wang, Mohammad Hossein Mosallanejad, Reza Ghanavati, Abdollah Saboori, Alejandro De Blas De Miguel, William Solórzano-Requejo, Yi Cai, Xiangyang Dong, Huangyi Qu, Najmeh Samadiani, Guangyan Huang, Austin Downey, Yanzhou Fu, Lang Yuan
Faculty Publications
Artificial intelligence-augmented additive manufacturing (AI2AM) represents a transformative frontier in digital fabrication, where artificial intelligence (AI) is embedded not as a peripheral tool, but as a central framework driving intelligent, adaptive, and autonomous additive manufacturing (AM) systems. The objective of this Roadmap is to present a comprehensive vision of the state-of-the-art developments in AI2AM while charting the future trajectory of this rapidly emerging field. As AM applications continue to expand across diverse sectors, conventional design and control strategies face growing limitations in scalability, quality assurance, and material complexity. AI uses tools like computer vision, generative design, and large language models …
Identifying The Strongest Novel Gene-Respiratory Disease Interactions For Rheumatoid Arthritis Risk, Vanessa L Kronzer, Rebecca T Brooks, Anne K Shurtz, Xiaosong Wang, Elizabeth J Atkinson, John M Davis, Jeffrey A Sparks, James R Cerhan, Elena K Joerns, Robert Vassallo, Cynthia S Crowson
Identifying The Strongest Novel Gene-Respiratory Disease Interactions For Rheumatoid Arthritis Risk, Vanessa L Kronzer, Rebecca T Brooks, Anne K Shurtz, Xiaosong Wang, Elizabeth J Atkinson, John M Davis, Jeffrey A Sparks, James R Cerhan, Elena K Joerns, Robert Vassallo, Cynthia S Crowson
Faculty, Staff and Students Publications
Objective: We aimed to identify the strongest individual gene-respiratory interactions for rheumatoid arthritis (RA) risk.
Methods: This case-control study used the Mayo Clinic (MC) and Mass General Brigham (MGB) biobanks for discovery and validation, respectively. We matched criteria-confirmed incident RA cases to four non-RA controls on age, sex, and duration electronic health record (EHR) history. Genetic exposures included known RA risk alleles. We identified respiratory diseases by codes and defined "respiratory burden" as the total number of respiratory codes divided by EHR duration before index date of RA. Using logistic regression models adjusting for potential confounders, we estimated odds ratios …
Phenome-Wide Analysis Of Copy Number Variants In 470,727 Uk Biobank Genomes, Xueqing Zoe Zou, Fengyuan Hu, Haiyi Lou, Oliver S Burren, Xiaoyin Li, Karyn Megy, Eleanor Wheeler, Qiang Wu, Santosh S Atanur, Marcin Karpinski, Douglas Loesch, Zammy Fairhurst-Hunter, Sri V V Deevi, Erin Oerton, Sean Wen, Xiao Jiang, Cecilia Salvoro, Jonathan Mitchell, Abhishek Nag, Ben Hollis, Amanda O'Neill, Jen Harrow, Stewart Macarthur, Sebastian Wasilewski, Sean O'Dell, Lifeng Tian, Katherine R Smith, Guillermo Del Angel, Margarete Fabre, Ryan S Dhindsa, Quanli Wang, Slavé Petrovski, Keren Carss
Phenome-Wide Analysis Of Copy Number Variants In 470,727 Uk Biobank Genomes, Xueqing Zoe Zou, Fengyuan Hu, Haiyi Lou, Oliver S Burren, Xiaoyin Li, Karyn Megy, Eleanor Wheeler, Qiang Wu, Santosh S Atanur, Marcin Karpinski, Douglas Loesch, Zammy Fairhurst-Hunter, Sri V V Deevi, Erin Oerton, Sean Wen, Xiao Jiang, Cecilia Salvoro, Jonathan Mitchell, Abhishek Nag, Ben Hollis, Amanda O'Neill, Jen Harrow, Stewart Macarthur, Sebastian Wasilewski, Sean O'Dell, Lifeng Tian, Katherine R Smith, Guillermo Del Angel, Margarete Fabre, Ryan S Dhindsa, Quanli Wang, Slavé Petrovski, Keren Carss
Duncan NRI Faculty and Staff Publications
Copy number variants (CNVs) are key drivers of human diversity and disease risk1. Here we evaluate the role of CNVs across a broad range of human phenotypes and diseases by analysing CNVs from 470,727 UK Biobank whole-genome sequences and conducting a variant- and gene-level phenome-wide association study (PheWAS) with 2,941 plasma protein abundance measurements, 13,336 binary clinical phenotypes and 1,911 quantitative traits. Proteomic analyses validated functional associations of CNVs with nearby genes (cis-protein quantitative trait loci; cis-pQTLs)—with deletions and duplications typically associated with reduced and increased protein levels, respectively—and uncovered previously unknown protein–protein interactions …
Tfeb Degradation Is Regulated By An Ikk/Β-Trcp2 Phosphorylation-Ubiquitination Cascade, Yan Xiong, Jaiprakash Sharma, Meggie N Young, Wen Xiong, Ali Jazayeri, Karl F Poncha, Ma Xenia G Ilagan, Qing Wang, Bei Gao, Hui Zheng, Nicolas L Young, Marco Sardiello
Tfeb Degradation Is Regulated By An Ikk/Β-Trcp2 Phosphorylation-Ubiquitination Cascade, Yan Xiong, Jaiprakash Sharma, Meggie N Young, Wen Xiong, Ali Jazayeri, Karl F Poncha, Ma Xenia G Ilagan, Qing Wang, Bei Gao, Hui Zheng, Nicolas L Young, Marco Sardiello
Center on Aging Staff Publications
Transcription factor EB (TFEB) is a master regulator of lysosomal biogenesis and cellular clearance pathways. TFEB activity is tightly controlled by multiple post-translational mechanisms, but the exact molecular mechanism controlling its stability has remained elusive. Here, we identify the IκB kinase (IKK) complex as a key regulator of TFEB protein stability through a phosphorylation-ubiquitination cascade. A high-content kinase inhibitor screen reveals that IKK inhibition increases TFEB protein levels, and genetic ablation of IKK components increases TFEB stability, upregulates lysosomal genes, and enhances lysosomal biogenesis and degradative capacity. Mechanistically, we show that IKK phosphorylates TFEB on a cluster of serine residues …
Temporal Dynamics Of Online Shopping: A Multidimensional Clustering Approach For Optimizing Time-Specific Advertising Strategies, Hye Ra Oh, Yunjae Cheong
Temporal Dynamics Of Online Shopping: A Multidimensional Clustering Approach For Optimizing Time-Specific Advertising Strategies, Hye Ra Oh, Yunjae Cheong
Asia Marketing Journal
This study clusters consumers according to their hourly online shopping consumption patterns and develops optimized advertising strategies that can be practically applied by companies. Specifically, we considered multidimensional variables related to consumers, including demographic characteristics, shopping frequency, information search and content consumption characteristics, and lifestyle traits. We explored consumer types by comparing various clustering algorithms and applying the optimal clustering method for each time period. The analysis results show significant differences in payment amounts according to payment time periods. Regarding consumer types, consumption tendencies are distinctly differentiated by payment time periods, with each cluster showing different characteristics. This study is …
Are You Ready To Embrace Ai-Generated Art? Exploring The Differential Effects Of Ai Versus Human Agents On Consumer Response, Seojin Stacey Lee, Yaeri Kim, Kiwan Park
Are You Ready To Embrace Ai-Generated Art? Exploring The Differential Effects Of Ai Versus Human Agents On Consumer Response, Seojin Stacey Lee, Yaeri Kim, Kiwan Park
Asia Marketing Journal
With a growing integration of artificial intelligence (AI) into creative domains, understanding its impact on consumer responses remains a critical area of inquiry. This research examines how agent type (AI vs. human) and art type (fine art vs. art-infused product) influences consumer purchase intention, along with the underlying psychological mechanism. Across three empirical studies, we find that consumers report higher purchase intention for art-infused products compared to fine art when created by AI. In contrast, this difference in purchase intention is diminished when the products are created by human artists. Perceived incompatibility functions as a moderated mediator in this process. …
Lessons Learned From Global Responses To Criminal Abortion Laws, Cynthia Soohoo
Lessons Learned From Global Responses To Criminal Abortion Laws, Cynthia Soohoo
Fordham Law Review Online
No abstract provided.
Asking Hospitals To Do Their Share, Kimberly Mutcherson
Asking Hospitals To Do Their Share, Kimberly Mutcherson
Fordham Law Review Online
No abstract provided.
Law's Limits: Abortion And The Social Determinants Of Health, Maya Manian
Law's Limits: Abortion And The Social Determinants Of Health, Maya Manian
Fordham Law Review Online
No abstract provided.
Abortion, Power And The Future Of Healthcare, Elizabeth Kukura
Abortion, Power And The Future Of Healthcare, Elizabeth Kukura
Fordham Law Review Online
No abstract provided.
Continued Resistance And Resilience After Dobbs, David S. Cohen, Carole Joffe
Continued Resistance And Resilience After Dobbs, David S. Cohen, Carole Joffe
Fordham Law Review Online
No abstract provided.
Deferred Action Theory As A Framework For Adaptive Educational Procurement: Navigating Uncertainty And Digital Transformation In Education Systems, Herdiana Herdiana, B. Yuliarto Nugroho, Andreo Wahyudi Atmoko
Deferred Action Theory As A Framework For Adaptive Educational Procurement: Navigating Uncertainty And Digital Transformation In Education Systems, Herdiana Herdiana, B. Yuliarto Nugroho, Andreo Wahyudi Atmoko
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
Public procurement constitutes a significant portion of national expenditure and directly affects economic growth, service delivery, and governance quality. In Indonesia, education sector procurement absorbs more than half of the allocated budget but remains vulnerable to inefficiencies, rigid procedures, and corruption risks. This study aims to conceptualize an adaptive framework for Public Procurement Business Process Management (PP-BPM) that addresses environmental uncertainty, digital transformation, and governance challenges. This conceptual study integrates Deferred Action Theory (DAT), Emergent Business Processes (EBP), and Business Process Management (BPM) to develop a multi-level framework for procurement. The analysis covers strategic, managerial, and operational dimensions, emphasizing deferment …
Ibu Kota Nusantara Sebagai Daerah Khusus Berdasarkan Desentralisasi Asimetris, Krisna Bagas Purwopangestu, Sri Wahyuningsih
Ibu Kota Nusantara Sebagai Daerah Khusus Berdasarkan Desentralisasi Asimetris, Krisna Bagas Purwopangestu, Sri Wahyuningsih
Jurnal Hukum & Pembangunan
This research examines the legal issue concerning the administration of regional government in Nusantara Capital City (IKN) which has been consider by some scholars as demonstrating deviations from the principle of decentralization. This research takes a position contrary to the mainstream legal discourse that argues there is a conceptual deviation in the model of regional governance in IKN. This research is normative legal research employing a conceptual approach and statutory approach with data collected through library research. This research argues that the administration of regional government in IKN does not indicate any deviation from the principle of decentralization. IKN is …
Hukum Islam Dalam Hukum Nasional, Prof. Dr. Ismail Suny, S.H. M.Cl.
Hukum Islam Dalam Hukum Nasional, Prof. Dr. Ismail Suny, S.H. M.Cl.
Jurnal Hukum & Pembangunan
Abstract
Beyond The Acre, James Werner
Beyond The Acre, James Werner
GIS Technology Conference 2026
The presentation will focus on a recent project done for the Tippecanoe County Assessor's Office using Blackshark Ai ORCA HUNTER Artificial Intelligence technology integrated with ESRI ARC GIS Online in order to determine land use for assessment purposes and assignments of homestead outlined in the following story map https://storymaps.arcgis.com/stories/e622370b225b480286ee3de074050a0b/print
Technology, Privacy, And Public Interaction: A Double-Edged Sword., Scott Teruya Aas, Lanie Wright
Technology, Privacy, And Public Interaction: A Double-Edged Sword., Scott Teruya Aas, Lanie Wright
GIS Technology Conference 2026
• Utilizing Technology (Street-Level and Aerial Imagery) to facilitate inspections and verify property data • IAAO Mass Appraisal of Real Property Standard (Section 3.3.5) • Interactions with the General Public • What are the legal issues? Different Public and Private examples • Technology used for Privacy Issues (Blurring of Faces and License Plates) • Examples of non-standard Blurring Requests
The Rise Of The “Religious Nones” And The Future Of The American Social Contract: Policy Implications Of A Secularizing Electorate, Vituli Musukuma
The Rise Of The “Religious Nones” And The Future Of The American Social Contract: Policy Implications Of A Secularizing Electorate, Vituli Musukuma
Helms School of Government Spring Public Policy Conference
No abstract provided.
African Union And Electoral Transparency In Africa, Virgile Samba Moussinga
African Union And Electoral Transparency In Africa, Virgile Samba Moussinga
Helms School of Government Spring Public Policy Conference
No abstract provided.
Beyond Community Policing: Integrating Stability Policing Models As A Framework In Addressing Conflicts, Instability And Emerging Extremism In Northern Ghana, Peter Joilah Lambon
Beyond Community Policing: Integrating Stability Policing Models As A Framework In Addressing Conflicts, Instability And Emerging Extremism In Northern Ghana, Peter Joilah Lambon
Helms School of Government Spring Public Policy Conference
No abstract provided.
Deterrence Under Strain: Assessing Us-Japan Strategic Alignment, Kaitlyn Elizabeth Early, Carl Rehberg
Deterrence Under Strain: Assessing Us-Japan Strategic Alignment, Kaitlyn Elizabeth Early, Carl Rehberg
Helms School of Government Spring Public Policy Conference
No abstract provided.
The “Crisis” Of Democratic Systems: Problem Or Challenge? A Christian Approach To The Thought Of Alexis De Tocqueville (1805-1859), Antonio Lattanzio Pr. Dr.
The “Crisis” Of Democratic Systems: Problem Or Challenge? A Christian Approach To The Thought Of Alexis De Tocqueville (1805-1859), Antonio Lattanzio Pr. Dr.
Helms School of Government Spring Public Policy Conference
No abstract provided.
A Renewed American Conservativism Or The End Of The American Republic?, Virgile Samba Moussinga
A Renewed American Conservativism Or The End Of The American Republic?, Virgile Samba Moussinga
Helms School of Government Spring Public Policy Conference
No abstract provided.
Tribal Sovereignty In The 21st Century: The Divergence Of The Founder’S Vision To Embracing Tribal Exclusivity, Travis Younce
Tribal Sovereignty In The 21st Century: The Divergence Of The Founder’S Vision To Embracing Tribal Exclusivity, Travis Younce
Helms School of Government Spring Public Policy Conference
No abstract provided.
Security Partnerships In West Africa And The Sahel: Strategies To Prevent Violent Extremism And Terrorism Spillover Into Ghana, Afua Boatemaa Yakohene, Mary Prentice, Peter Joilah Lambon, Ben Ellis
Security Partnerships In West Africa And The Sahel: Strategies To Prevent Violent Extremism And Terrorism Spillover Into Ghana, Afua Boatemaa Yakohene, Mary Prentice, Peter Joilah Lambon, Ben Ellis
Helms School of Government Spring Public Policy Conference
No abstract provided.
Artificial Intelligence, U.S.- China Trade Dyanamics, And Their Implications For African Economics: Assessing Opportunities, Risks And Policy Responses, Jelili Afolabi
Helms School of Government Spring Public Policy Conference
No abstract provided.