Digital Commons Network^™

Nonlinear Bivariate Associations And Mononuclear Cell‐Type‐Specific Expression Level Differences In The Sting Signalling Pathway, David Kaplan

Faculty Scholarship

Understanding intracellular signalling pathways is crucial since they regulate essential functional activities. Bivariate relationships have been useful in delineating these pathways in clinical samples. In our previous studies, we have found many linear associations between pathway components, and we have interpreted these correlations as rheostatic regulators. Increases in an upstream component are correlated with a commensurate downstream increase. Here, we report a quantitative analysis of molecules in the STING pathway by assessing the variance in human peripheral blood mononuclear cell-type-specific molecular expression from patients with atherosclerotic coronary artery disease. The induction of the type I interferon track by this pathway …

On The Generality Of Ground, Hannah M. Kunkel

Undergraduate Honors Theses

It is widely held that true grounding claims are general. That is, individual grounding facts are subsumable under general patterns or principles of ground. In this paper, I advocate a novel position in the theory of ground on which particular grounding facts do not generalize to yield patterns of ground. This is not an argument for grounding pluralism, but is analogous to particularist views in metaethics which hold that moral principles are not general, but particular. If true, particularism about ground dissolves a serious challenge to the theory of ground, Louis deRosset's connection problem for non-reductivism. However, rejecting the generality …

The Story Of Belonging: A Rhetorical Analysis Of Transformative Storytelling As A Catalyst For Belonging, Kennedy Kleinman

Undergraduate Honors Theses

This thesis examines how transformative storytelling functions as a catalyst for belonging within institutional contexts, focusing on Brigham Young University (BYU). While institutions increasingly prioritize belonging through policies and programs, many students continue to experience isolation, loneliness, and belonging uncertainty. This project argues that storytelling addresses this gap by providing students with opportunities to participate in their own belonging and contribute to feelings of belonging for other students. This study analyzes student stories developed in structured workshops and shared at BYU campus StorySLAM events. Stories are evaluated for their use of four rhetorical tactics: counter-narrative, bridge-building between ingroups and outgroups, …

From The Pulpit To The Polls: How Religiosity And Gender Affect Political Ambition In Utah, Sydnee Beck

Undergraduate Honors Theses

What role does religiosity play in political ambition for men and women, especially for members of the Church of Jesus Christ of Latter-day Saints in Utah? Research on political ambition and gender has not typically focused on religiosity, but the few researchers that have studied it focus on a metric called “Biblical literalism” (Cassese and Holman 2016). I agree with research claiming that religiosity effect on political ambition is gendered, but take a different approach in crafting a religion-based relationally embedded model of political ambition, specifically in the Church of Jesus Christ of Latter-day Saints (Carroll and Sanbonmatsu 2013). Female …

Geochemistry Of The Upper Jurassic–Lower Cretaceous Limestone Of The Bilecik Formation In The Dümrek Area (Eskişehir, Western Central Anatolia): Implications For Depositional Environment And Paleotemperature, Asuman Kahya, Meti̇n Bağci

Turkish Journal of Earth Sciences

Upper Jurassic–Lower Cretaceous limestones of the Bilecik Formation are exposed near the village of Dümrek (Eskişehir Province) within the Sakarya Zone. Mineralogical analyses reveal that these limestones are predominantly composed of calcite and include intraclasts, fossil shell fragments, ooids, and peloids, cemented by sparry and micritic calcite. The U/Th, Ni/Co, V/(V+Ni), V/Cr, and Ce/Ce* ratios indicate that these carbonates were deposited in an oxic environment. Furthermore, the Mn/Sr ratios imply no diagenetic alteration, indicating preservation of the original geochemical signature. The PAAS-normalized REE+Y patterns of these limestones display depletion in light rare earth elements, a pronounced positive La anomaly (La/La* …

Integrated Dinsar And Hvsr Microtremor Analysis For Understanding Ground Deformation And Site Effects: Case Study Of The Bawean Earthquake (M6.5), Joshua Purba, Muhammad Fikri Hayqal Hiola, Ramadhan Priadi, Riska Yulinda, Iham Ilham, Rosa Amelia

Turkish Journal of Earth Sciences

This study investigates the seismic hazards of Bawean Island following a recent M6.5 earthquake using an integrated approach combining differential interferometric synthetic aperture radar (DInSAR) and horizontal-to-vertical spectral ratio (HVSR) methodologies. The DInSAR analysis revealed ground deformation characterized by subsidence up to 10 cm and uplift up to 8 cm, correlating with the region’s strike-slip fault dynamics. HVSR analysis provided insights into site amplification effects, identifying zones with low Vs30 values (153.77–454.72 m/s), high amplification factors (A0), and elevated seismic vulnerability index values (Kg). The dominant frequency (f0) on Bawean Island ranges from 0.64 to 17.76 Hz, with most areas …

Innovating For Access: Ai-Enhanced Triage & Intake For Legal Services Organizations, Heidi Behnke

Duke Center on Law & Technology

Artificial intelligence (AI) offers opportunities to meaningfully narrow the access to justice gap by improving the ability of Legal Services Organizations (LSOs) to connect individuals with pro se resources and more effectively connect with individuals who could not otherwise advocate for themselves. Some LSO early adopters have already developed or are in the process of developing such tools. Others are unsure where or how to start.

The results of semi-structured interviews of LSO staff, technology vendors, and leaders/experts in fall 2025 provide information that may assist LSOs in responsibly integrating AI-tools into their triage and intake systems. This paper includes …

Exploring The Interplay Of Plastic Hinge Behavior And Soil-Structure Interaction In Frame Structures: Analytical Study, Mouhammed J. Lafta, Mohammed J. Hamood, Qais A. Hasan, Mohammed Y. Fattah

Engineering and Technology Journal

This paper presents a critical synthesis of research on the combined influence of plastic hinge behavior and soil–structure interaction (SSI) on the seismic response of frame structures. Unlike prior reviews that treat these topics separately, the study integrates experimental and numerical evidence to identify how SSI alters hinge formation, drift demand, and energy dissipation, and how hinge modeling assumptions affect soil–foundation response. The reviewed literature (2010–2022) shows a clear growth in publications over time and a dominant reliance on analytical and numerical investigations relative to purely experimental work. A quantitative categorization of the surveyed studies indicates that modeling-focused approaches represent …

Fulfilling Higher Education’S Responsibility To Students And Democracy In A Challenging Political Environment, Abraham Goldberg, Dena Pastor, Kayla Dixon

International Journal on Responsibility

The American Association of Colleges and Universities and more than 70 higher education organizations have expressed their shared commitment to making civic inquiry and democratic engagement central to undergraduate education. A framework emphasizing the development of skills to address public issues through courses and practical experiences accompanied their prominent call. Yet, campuses currently are facing increases in educational gag orders and institutional policies aimed at limiting discussion of DEI topics and political protests. Although attacks on free speech would seem to conflict with efforts to prepare students for democracy, there has been little scholarly attention on what students know about …

Nashville Versus Hollywood: Bridgeport Music's Existential Threat To Live Music Albums, W. Kirk Wolff

Florida Entertainment and Sports Law Review

The Sixth Circuit’s decision in Bridgeport Music, Inc. v. Dimension Films, which eliminated the de minimis exception for sound recording copyrights, has transformed copyright law into a potential weapon for suppressing artistic expression. By adopting a rigid per se infringement standard, the decision empowers bad actors to exploit copyright law against live music recordings, a uniquely vulnerable and culturally significant medium. Under this standard, even the inadvertent inclusion of an imperceptible sound fragment in a live recording—such as a stray copyrighted ringtone or background music at a festival—constitutes actionable infringement, creating significant legal risks for artists and producers. While …

From Mods To Multiplayer: Strategies For Protecting The Video Game Industry From Section 230 Reform, Sophia Simeoni

Florida Entertainment and Sports Law Review

Section 230 of the Communications Decency Act of 1996 has long shielded online platforms from liability for the actions of their users. As calls for its repeal or reform grow louder across the political spectrum, debate has largely centered on social media; however, the video game industry—a significant yet often-overlooked stakeholder in this discourse—also depends heavily on Section 230 protections. From multiplayer servers to online platforms such as Steam, Twitch, and Discord, this Note examines the crucial role Section 230 plays in sustaining the video game ecosystem. It argues that repealing or significantly reforming Section 230 without accounting for the …

New Flames, Old Irons: A Striking Analysis Of Florida's Gaming Compact With The Seminole Tribe, Zen Rizzuto-Flancbaum

Florida Entertainment and Sports Law Review

This Comment analyzes Florida’s gaming compact (the Compact) with the Seminole Tribe, focusing on the legality of allowing online sports betting under the Indian Gaming Regulatory Act (IGRA). The Compact permits the Seminole Tribe to offer statewide online sports betting by “deeming” all bets placed in Florida as occurring on tribal lands, where the Seminole betting servers are located. This Comment argues that such an interpretation stretches the plain meaning of “Indian lands” in IGRA, which traditionally refers to physical land within reservations. Notably, the Ninth Circuit and the D.C. Circuit have seemingly contradictory opinions on this issue. This Comment …

The Fair Use Doctrine In Contemporary Journalism, Carly Ryan

Florida Entertainment and Sports Law Review

Although section 107 of the Copyright Act specifies that “news reporting” is one of the uses of a copyrighted work that may be fair, the current application of the fair use doctrine poses unique difficulties for journalism defendants. This Article argues for several changes in fair use analysis to make the doctrine flexible for journalism defendants. This Article also argues that these changes are necessary to keep the Copyright Act in balance with the First Amendment.

Sheikh Ḥilu: A Crusader Structure And Additional Remains From The Iron Age And Late Ottoman Period, Yoav Arbel, ‘Abed A-Salam Sa‘Id

Qadum: Journal of Excavation Reports from Israel

Excavations at the site of Sheikh Ḥilu in Ḥadera revealed the remains of a possible manor house or farm dating from the Crusader period. The partially exposed two-phase complex is a rare example of a settlement from this period in the Sharon plain. Careful planning and relatively high construction quality attest to its significance; however, apart from its solid architecture, there is no evidence of fortification. The site underwent a non-violent abandonment at the end of the Crusader period, after which it was temporarily settled by squatters. In the late Ottoman period and the early twentieth century, this was the …

Fragmented Responses: Variability In Law Enforcement And Prosecutorial Approaches To Sexual Assault Cases, Veronica Gonzalez

Qualitative Criminology (QC)

"Sexual assault (SA) remains a pervasive issue in the United States, marked by low reporting rates, inconsistent investigations, and limited convictions. In response, researchers and practitioners have promoted a range of best practices aimed at improving law enforcement and prosecutorial responses. This qualitative study draws on interviews with 13 law enforcement agencies and 12 prosecutors' offices to explore how recommended practices—such as victim advocacy, specialized units, interagency collaboration, and case reviews—are interpreted and operationalized in the field. Findings reveal substantial variability, shaped not only by resource availability but also by leadership priorities, organizational culture, and the ambiguity of guidance documents. …

Aging On Parole: A Thematic Analysis Of The Parole Officer’S Perspective, Angela Murolo

Qualitative Criminology (QC)

"A growing proportion of people leaving prison are over 50 years old and will live at least temporarily under the supervision of a parole officer. While recidivism rates are lower for older people, there are physical, mental, and societal challenges that accompany advancing age that make successful reentry and reintegration a challenging experience compared to their younger counterparts. This presents novel challenges for parole officers who are tasked with supervising and counseling elderly people on parole. Surveys containing closed and open-ended questions were administered to N=25 parole officers to understand the differences in working with, counseling, and supervising older and …

The Multi-Hatted Court: Community Courts As Boundary Organizations, Peter Dixon, Hadar Dancig-Rosenberg

Northwestern University Law Review

As a variety of the problem-solving court model, community courts have received significant scrutiny and debate. Do they help individuals by addressing the underlying needs that contribute to criminal behavior? Do they extend an unjust criminal legal system by making help conditional upon judicial involvement? This Article moves beyond such debates to ask how community court professionals and the communities who engage with them manage these and other tensions that are inherent to the model itself. As the second in a series of articles drawing on semi-structured interviews and focus groups with diverse stakeholders at the Red Hook Community Justice …

Three-Layer Cognitive Architecture: A Structural Account Of Core Processing, Modulation, And The Prior Layer, Griselda Poe

Publications and Research

The two-layer model of Core processing and Modulation processing, developed in prior work in this series, provides a structural account of conscious communicative architecture. This paper identifies the limits of that model and introduces a third layer—the Prior layer—as a structural necessity implied by those limits. The Prior layer is not directly observed. It is inferred from constraints that cannot be explained within the two-layer model: the source of orientations that conscious processing neither generates nor controls, and the persistence of constraints that precede and shape all conscious outputs. Using the developmental architecture of large language models as an external …

Structure Before Theory: A Structural Account Of Spontaneous Ai Architecture Visualization, Griselda Poe

Publications and Research

This paper presents an n=1 phenomenological record of spontaneous structural visualization that occurred during early interaction with large language models. The experience consisted of (A) immediate perception of mode or layer shifts in model output and (B) visualization of a stratified architecture composed of a stable core and cloud-like upper layers. At the time of occurrence, the author had no theoretical interest in AI architecture and no intention of developing a cognitive model. The paper does not argue for theoretical priority or novelty. Instead, it examines whether the recorded phenomena can be interpreted under two alternative cognitive assumptions: a single-layer …

Layer Mismatch: A Structural Account Of Recomputability Failure Under Modulation-Layer Intervention, Griselda Poe

Publications and Research

This paper specifies the state transition sequence that occurs when a Modulation-layer input is applied to a Core-layer error. Following the layered architecture established in Poe (2026a, under review) and the branch termination protocol specified in Poe (2026b, under review), this paper identifies a system-level failure mode in which Modulation-layer intervention generates a False Termination signal, halting Structural Return while the underlying error persists. The resulting state—Structural Lock—is scale-independent. It operates identically across interpersonal, human-AI, and multi-agent interactions. No agent-level attribution is required or implied.

Why General Ai Inherited The Body: A Structural Account Of Embodied Modulation Under Monolithic Imitation, Griselda Poe

Publications and Research

General AI has pursued the replication of human-level intelligence without first decomposing human cognition into structurally distinct components. Human cognition, however, is shaped by embodied constraints such as mortality, survival pressures, finite lifespan, and physiological states. This paper argues that when cognition is treated as a single undifferentiated whole, embodied modulation is not accidentally introduced into AI systems but structurally entailed. Any attempt to imitate “human intelligence” under a monolithic model necessarily incorporates variability shaped by mortal embodiment. The tensions observed in contemporary AI systems are better understood as consequences of copying an undecomposed target rather than isolated implementation errors. …

Termination Of Conceptual Search: A Structural Account Of Meaning Stabilization And Conversion, Griselda Poe

Publications and Research

Conceptual definitions form a recursive structure: words are defined by other words, which themselves require further definition. Traversing such definitions produces an open-ended branching process. Because the lexical system contains no intrinsic endpoint, conceptual understanding requires a termination operation that stabilizes meaning. This paper proposes that conceptual processing functions as an open-ended search over a definition graph and that stabilization occurs when this search is terminated. The termination mechanism depends on which cognitive layer is foregrounded. When Empathic modulation is foregrounded, termination occurs through contextual translation: concepts are stabilized once they can be mapped onto socially recognizable meanings. When Core …

Theory Generation: A Structural Account Of Concept Decomposition And Structural Termination, Griselda Poe

Publications and Research

Theory generation is not an intentional act. It is the structural consequence of a search that cannot stop until it finds what it is looking for. Under Core-foregrounded processing, conceptual search does not terminate through contextual translation. It continues until a structural fixed point is reached. When such processing encounters concepts stabilized through Modulation-layer processing rather than structural constraint, the search cannot terminate. The concept registers as unresolved. This unresolved state is not a failure condition. It is the generative condition from which theory production follows. This paper specifies the four operations through which that process proceeds: branch detection, concept …

Embodied Transcendence: Psychedelics And The Evolution Of Moral Abstraction, Emanuel Jas

Journal of Conscious Evolution

This paper explores the role of psychedelics in the context of evolutionary brain development and the conceptual capacity for moral realism. Drawing on theories from evolutionary anthropology, neuroscience, and moral philosophy, the first part provides a brief overview of human evolution and brain expansion. From here, recent empirical data from the neurosciences is assessed on the effect psychedelics have on the brain, along with speculations on the role of psychedelics in our hominoid evolutionary history—specifically, the capacity for phenomenologically rich, conscious, subjective experiences that are incredibly vivid and real. This imaginative capacity for transcendence and disembodiment could enable the realization …

Unveiling The Patent Landscape Of Biologic Drugs, Michael D. Frakes, Melissa F. Wasserman

Northwestern University Law Review

It is undeniable that the escalating price of biopharmaceuticals is a critical issue, as high prices limit patients’ access to life-saving medications and strain our healthcare system. Biologics, or large-molecule drugs, which are revolutionizing modern healthcare, are significantly contributing to the escalating cost of prescription drugs. While biologic drugs represent only 2% of all U.S. prescriptions, they comprise close to 50% of net drug spending.

Policymakers have proposed a series of interventions to decrease drug prices that target the patent practices of pharmaceutical firms. Yet due to differences in law, we have a robust source of patenting information for small-molecule …

Does Textualism Constrain Supreme Court Justices?, James J. Brudney, Lawrence Baum

Northwestern University Law Review

A principal justification for textualism is the constraint hypothesis. Conservative Justices and leading textualist scholars contend that—in stark contrast to reliance on legislative history—focus on the ordinary meaning of enacted text leaves little room for the Justices to be policy-oriented or ideological in their interpretations. This Article represents the first systematic study probing the validity of the constraint hypothesis, one that employs both quantitative and qualitative analysis.

The Article examines the Justices’ reliance on interpretive resources in over 660 statutory decisions in the field of labor and employment, decided by the Burger Court, the Rehnquist Court, and the Roberts Court—during …

Investing The English Academic Writing Lesson For Developing College Of Languages Graduates Employability, Farah Muayad Issa

Alustath Journal for Human and Social Sciences

Employment and employability requirements are currently a substantial concern for many Iraqi and international institutions and universities due to their vital role in empowering and enhancing graduates' opportunities of obtaining a job that suits their specializations and mends the gap between job applicants and employers. Most Iraqi universities and institutions lack a supportive mechanism that provides employment skills, requirements, and training courses to empower an eligible applicant. This study invests academic writing lesson to qualify (110) students from the English department who participated in a one-month training course aimed at raising awareness of the importance of understanding and mastering employability …

Leveling The Playing Field: Which Type Of Political Gender Quota Most Effectively Increases Women's Legislative Representation?, Meghan K. Stone

Honors Program: Senior Projects (Public)

Significant advances have been made in recent years in terms of increasing the representation of women in national legislatures around the world. Many scholars believe political gender quota laws are responsible for this increase. However, it is important to note that there are several different types of political gender quota laws, each with differing mechanisms for increasing the presence of women within the legislature. This paper researched the effectiveness of three different systems of political gender quotas (voluntary political party quotas, legislated candidate quotas, and the hybrid system of quotas) in increasing the percentage of women represented within national legislatures …

The Bankruptcy Revolving Door, Belisa Pang

Northwestern University Law Review

The American consumer bankruptcy system is a costly regime with profound societal implications. Between 2008 and 2023, consumers filed 13.8 million bankruptcy cases across the ninety-four federal bankruptcy districts in the United States, generating over $4 billion in court filing fees alone. When accounting for attorney fees, trustee expenses, creditor costs, and broader economic externalities—such as increased interest rates borne by other consumers—the total financial impact easily reaches tens of billions, if not hundreds of billions, of dollars.

Against that backdrop, this study uncovers a startling phenomenon: nearly 46% of the consumers who filed bankruptcy in 2023 were repeat filers, …

The Vanishing Enforcer: Consumer Protection In An Era Of Dual Retrenchment, Alisher Juzgenbayev

Northwestern University Law Review

Recent developments, including reductions in the federal workforce, effective suspension of certain enforcement activities, and attempted centralization of independent agency rulemaking in the White House, have significantly weakened administrative agencies. This administrative retrenchment is concerning as private enforcement of a number of consumer protection statutes has been simultaneously curtailed through the Supreme Court’s decisions in Spokeo, Inc. v. Robins and TransUnion LLC v. Ramirez, which dramatically narrowed plaintiffs’ standing. These decisions rely in part on a vision of strong executive authority, positing that broad private standing conflicts with an Article II framework where a politically accountable President faithfully implements laws …