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Articles 99511 - 99540 of 819612

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Examining The Role Of Microglia In Diabetic Retinopathy: Phenotypes, Mechanisms, And Therapies, Charles W. Pfeifer Oct 2023

Examining The Role Of Microglia In Diabetic Retinopathy: Phenotypes, Mechanisms, And Therapies, Charles W. Pfeifer

Arts & Sciences Graduate Student Theses and Dissertations

Retinal microglia activation and function is a pivotal component of ocular disease pathology, but their involvement in diabetic retinopathy, a complex neurovascular complication of diabetes, remains unclear. The purpose of this thesis work is to thoroughly examine features of microglia activation in DR, identify mechanistic underpinnings of their contributions to neuroinflammatory features of disease pathogenesis, and assess immunotherapeutic targeting of microglia as a potential approach to treating early-stage DR. Here, we show that chronic hyperglycemia elicits morphological, ultrastructural, and transcriptional changes in retinal microglia during early-stage DR while other elements of the retinal neurovascular unit remain unperturbed. Through chronic ablation …

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Manananggal Terrorizes Ateneo: Fiction Versus The Apocalypse, Jessica Zafra Oct 2023

Manananggal Terrorizes Ateneo: Fiction Versus The Apocalypse, Jessica Zafra

Perspectives in the Arts and Humanities Asia

Excerpt: Thank you very much to the committee on the Fr. Henry Lee Irwin, SJ, Chair for naming me this year’s [2019–20] chair holder. Chair holder? I feel like furniture. It’s an honor to be acknowledged by the academe because I don’t actually have a BA, and also I am what you call a popular writer. I don’t mean that everybody reads me, but that real people read me as opposed to the people who will write papers about me, so this, this is a great honor. Actually, as we go along, I will show you that not only is …

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Toll-Like Receptor 4 And Cd11b Expressed On Microglia Coordinate Eradication Of Candida Albicans Cerebral Mycosis, Yifan Wu, Shuqi Du, Lynn H Bimler, Kelsey E Mauk, Léa Lortal, Nessim Kichik, James S Griffiths, Radim Osicka, Lizhen Song, Katherine Polsky, Lydia Kasper, Peter Sebo, Jill Weatherhead, J Morgan Knight, Farrah Kheradmand, Hui Zheng, Jonathan P Richardson, Bernhard Hube, Julian R Naglik, David B Corry Oct 2023

Toll-Like Receptor 4 And Cd11b Expressed On Microglia Coordinate Eradication Of Candida Albicans Cerebral Mycosis, Yifan Wu, Shuqi Du, Lynn H Bimler, Kelsey E Mauk, Léa Lortal, Nessim Kichik, James S Griffiths, Radim Osicka, Lizhen Song, Katherine Polsky, Lydia Kasper, Peter Sebo, Jill Weatherhead, J Morgan Knight, Farrah Kheradmand, Hui Zheng, Jonathan P Richardson, Bernhard Hube, Julian R Naglik, David B Corry

Faculty, Staff and Students Publications

The fungal pathogen Candida albicans is linked to chronic brain diseases such as Alzheimer's disease (AD), but the molecular basis of brain anti-Candida immunity remains unknown. We show that C. albicans enters the mouse brain from the blood and induces two neuroimmune sensing mechanisms involving secreted aspartic proteinases (Saps) and candidalysin. Saps disrupt tight junction proteins of the blood-brain barrier (BBB) to permit fungal brain invasion. Saps also hydrolyze amyloid precursor protein (APP) into amyloid β (Aβ)-like peptides that bind to Toll-like receptor 4 (TLR4) and promote fungal killing in vitro while candidalysin engages the integrin CD11b (Mac-1) on microglia. …

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Early Antibody Treatment, Inflammation, And Risk Of Post-Covid Conditions, Kelly A Gebo, Sonya L Heath, Yuriko Fukuta, Xianming Zhu, Sheriza Baksh, Allison G Abraham, Feben Habtehyimer, David Shade, Jessica Ruff, Malathi Ram, Oliver Laeyendecker, Reinaldo E Fernandez, Eshan U Patel, Owen R Baker, Shmuel Shoham, Edward R Cachay, Judith S Currier, Jonathan M Gerber, Barry Meisenberg, Donald N Forthal, Laura L Hammitt, Moises A Huaman, Adam Levine, Giselle S Mosnaim, Bela Patel, James H Paxton, Jay S Raval, Catherine G Sutcliffe, Shweta Anjan, Thomas Gniadek, Seble Kassaye, Janis E Blair, Karen Lane, Nichol A Mcbee, Amy L Gawad, Piyali Das, Sabra L Klein, Andrew Pekosz, Evan M Bloch, Daniel Hanley, Arturo Casadevall, Aaron A R Tobian, David J Sullivan, Cssc-004 Consortium Oct 2023

Early Antibody Treatment, Inflammation, And Risk Of Post-Covid Conditions, Kelly A Gebo, Sonya L Heath, Yuriko Fukuta, Xianming Zhu, Sheriza Baksh, Allison G Abraham, Feben Habtehyimer, David Shade, Jessica Ruff, Malathi Ram, Oliver Laeyendecker, Reinaldo E Fernandez, Eshan U Patel, Owen R Baker, Shmuel Shoham, Edward R Cachay, Judith S Currier, Jonathan M Gerber, Barry Meisenberg, Donald N Forthal, Laura L Hammitt, Moises A Huaman, Adam Levine, Giselle S Mosnaim, Bela Patel, James H Paxton, Jay S Raval, Catherine G Sutcliffe, Shweta Anjan, Thomas Gniadek, Seble Kassaye, Janis E Blair, Karen Lane, Nichol A Mcbee, Amy L Gawad, Piyali Das, Sabra L Klein, Andrew Pekosz, Evan M Bloch, Daniel Hanley, Arturo Casadevall, Aaron A R Tobian, David J Sullivan, Cssc-004 Consortium

Faculty, Staff and Students Publications

Post-COVID conditions (PCCs) are common and have significant morbidity. Risk factors for PCC include advancing age, female sex, obesity, and diabetes mellitus. Little is known about treatment, inflammation, and PCC. Among 882 individuals with confirmed SARS-CoV-2 infection participating in a randomized trial of COVID-19 convalescent plasma (CCP) vs control plasma with available biospecimens and symptom data, the association between early CCP treatment, cytokine levels, and PCC was evaluated. Cytokine and chemokine levels were assessed at baseline, day 14, and day 90 using a multiplexed sandwich immunoassay (Meso Scale Discovery). Presence of any self-reported PCC symptoms was assessed at day 90. …

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Body Reprogramming For Fibromyalgia And Central Sensitivity Syndrome: A Preliminary Evaluation, Joseph W. Lanario, Esther Hudson, Cosima Locher, Annily Dee, Kerry Elliot, Anthony F. Davies Oct 2023

Body Reprogramming For Fibromyalgia And Central Sensitivity Syndrome: A Preliminary Evaluation, Joseph W. Lanario, Esther Hudson, Cosima Locher, Annily Dee, Kerry Elliot, Anthony F. Davies

More Faculty of Health Research

Objectives: Central sensitivity syndrome disorders such as fibromyalgia, provoke continued debate, highlighting diagnostic and therapeutic uncertainty. The Hyland model provides a way of understanding and treating the medically unexplained symptoms of central sensitivity syndromes using complexity theory and principles of adaption in network systems. The body reprogramming is a multi-modal intervention based on the Hyland model designed for patients living with medically unexplained symptoms. This preliminary, naturalistic and single-arm service evaluation set out to evaluate outcome after attending a body reprogramming course in patients living with fibromyalgia or central sensitivity syndrome. Methods: Patients diagnosed with fibromyalgia or central sensitivity syndrome …

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A Small-Molecule Inhibitor Of Topbp1 Exerts Anti-Myc Activity And Synergy With Parp Inhibitors, Fang-Tsyr Lin, Kang Liu, Lidija A Wilhelms Garan, Helena Folly-Kossi, Yongcheng Song, Shwu-Jiuan Lin, Weei-Chin Lin Oct 2023

A Small-Molecule Inhibitor Of Topbp1 Exerts Anti-Myc Activity And Synergy With Parp Inhibitors, Fang-Tsyr Lin, Kang Liu, Lidija A Wilhelms Garan, Helena Folly-Kossi, Yongcheng Song, Shwu-Jiuan Lin, Weei-Chin Lin

Faculty, Staff and Students Publications

We have previously identified TopBP1 (topoisomerase IIβ-binding protein 1) as a promising target for cancer therapy, given its role in the convergence of Rb, PI(3)K/Akt, and p53 pathways. Based on this, we conducted a large-scale molecular docking screening to identify a small-molecule inhibitor that specifically targets the BRCT7/8 domains of TopBP1, which we have named 5D4. Our studies show that 5D4 inhibits TopBP1 interactions with E2F1, mutant p53, and Cancerous Inhibitor of Protein Phosphatase 2A. This leads to the activation of E2F1-mediated apoptosis and the inhibition of mutant p53 gain of function. In addition, 5D4 disrupts the interaction of TopBP1 …

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Returning Incidentally Discovered Hepatitis C Rna-Seq Results To Copdgene Study Participants, Edwin K Silverman, Arthur Y Kim, Barry J Make, Elizabeth A Regan, Jarrett D Morrow, Craig P Hersh, James O'Brien, James D Crapo, Nadia N Hansel, Gerard Criner, Eric L Flenaugh, Douglas Conrad, Richard Casaburi, Russell P Bowler, Nicola A Hanania, R Graham Barr, Surya P Bhatt, Frank C Sciurba, Antonio Anzueto, Meilan K Han, Charlene E Mcevoy, Alejandro P Comellas, Dawn L Demeo, Richard Rosiello, Jeffrey L Curtis, Tricia Uchida, Carla Wilson, P Pearl O'Rourke Oct 2023

Returning Incidentally Discovered Hepatitis C Rna-Seq Results To Copdgene Study Participants, Edwin K Silverman, Arthur Y Kim, Barry J Make, Elizabeth A Regan, Jarrett D Morrow, Craig P Hersh, James O'Brien, James D Crapo, Nadia N Hansel, Gerard Criner, Eric L Flenaugh, Douglas Conrad, Richard Casaburi, Russell P Bowler, Nicola A Hanania, R Graham Barr, Surya P Bhatt, Frank C Sciurba, Antonio Anzueto, Meilan K Han, Charlene E Mcevoy, Alejandro P Comellas, Dawn L Demeo, Richard Rosiello, Jeffrey L Curtis, Tricia Uchida, Carla Wilson, P Pearl O'Rourke

Faculty, Staff and Students Publications

The consequences of returning infectious pathogen test results identified incidentally in research studies have not been well-studied. Concerns include identification of an important health issue for individuals, accuracy of research test results, public health impact, potential emotional distress for participants, and need for IRB permissions. Blood RNA-sequencing analysis for non-human RNA in 3984 participants from the COPDGene study identified 228 participants with evidence suggestive for hepatitis C virus (HCV) infection. We hypothesized that incidentally discovered HCV results could be effectively returned to COPDGene participants with attention to the identified concerns. In conjunction with a COPDGene Participant Advisory Panel, we developed …

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Constitutive Interleukin-7 Cytokine Signaling Enhances The Persistence Of Epstein-Barr Virus-Specific T-Cells, Sandhya Sharma, Tim Sauer, Bilal A Omer, Thomas Shum, Lisa A Rollins, Cliona M Rooney Oct 2023

Constitutive Interleukin-7 Cytokine Signaling Enhances The Persistence Of Epstein-Barr Virus-Specific T-Cells, Sandhya Sharma, Tim Sauer, Bilal A Omer, Thomas Shum, Lisa A Rollins, Cliona M Rooney

Faculty, Staff and Students Publications

The efficacy of therapeutic T-cells is limited by a lack of positive signals and excess inhibitory signaling in tumor microenvironments. We previously showed that a constitutively active IL7 receptor (C7R) enhanced the persistence, expansion, and anti-tumor activity of T-cells expressing chimeric antigen receptors (CARs), and C7R-modified GD2.CAR T-cells are currently undergoing clinical trials. To determine if the C7R could also enhance the activity of T-cells recognizing tumors via their native T-cell receptors (TCRs), we evaluated its effects in Epstein–Barr virus (EBV)-specific T-cells (EBVSTs) that have produced clinical benefits in patients with EBV-associated malignancies. EBVSTs were generated by stimulation of peripheral …

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Braf Inhibitors In Metastatic Colorectal Cancer And Mechanisms Of Resistance: A Review Of The Literature, Patricia Guerrero, Víctor Albarrán, María San Román, Carlos González-Merino, Coral García De Quevedo, Jaime Moreno, Juan Carlos Calvo, Guillermo González, Inmaculada Orejana, Jesús Chamorro, Íñigo Martínez-Delfrade, Blanca Morón, Belén De Frutos, María Reyes Ferreiro Oct 2023

Braf Inhibitors In Metastatic Colorectal Cancer And Mechanisms Of Resistance: A Review Of The Literature, Patricia Guerrero, Víctor Albarrán, María San Román, Carlos González-Merino, Coral García De Quevedo, Jaime Moreno, Juan Carlos Calvo, Guillermo González, Inmaculada Orejana, Jesús Chamorro, Íñigo Martínez-Delfrade, Blanca Morón, Belén De Frutos, María Reyes Ferreiro

Faculty, Staff and Students Publications

Metastatic colorectal cancer (mCRC) with mutated BRAF exhibits distinct biological and molecular features that set it apart from other subtypes of CRC. Current standard treatment for these tumors involves a combination of chemotherapy (CT) and VEGF inhibitors. Recently, targeted therapy against BRAF and immunotherapy (IT) for cases with microsatellite instability (MSI) have been integrated into clinical practice. While targeted therapy has shown promising results, resistance to treatment eventually develops in a significant portion of responsive patients. This article aims to review the available literature on mechanisms of resistance to BRAF inhibitors (BRAFis) and potential therapeutic strategies to overcome them.

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Advancements In Dendritic Cell Vaccination: Enhancing Efficacy And Optimizing Combinatorial Strategies For The Treatment Of Glioblastoma, Robert Subtirelu, Eric Teichner, Arjun Ashok, Chitra Parikh, Sahithi Talasila, Irina-Mihaela Matache, Ahab Alnemri, Victoria Anderson, Osmaan Shahid, Sricharvi Mannam, Andrew Lee, Thomas Werner, Mona-Elisabeth Revheim, Abass Alavi Oct 2023

Advancements In Dendritic Cell Vaccination: Enhancing Efficacy And Optimizing Combinatorial Strategies For The Treatment Of Glioblastoma, Robert Subtirelu, Eric Teichner, Arjun Ashok, Chitra Parikh, Sahithi Talasila, Irina-Mihaela Matache, Ahab Alnemri, Victoria Anderson, Osmaan Shahid, Sricharvi Mannam, Andrew Lee, Thomas Werner, Mona-Elisabeth Revheim, Abass Alavi

Student Papers, Posters & Projects

Glioblastomas (GBM) are highly invasive, malignant primary brain tumors. The overall prognosis is poor, and management of GBMs remains a formidable challenge, necessitating novel therapeutic strategies such as dendritic cell vaccinations (DCVs). While many early clinical trials demonstrate an induction of an antitumoral immune response, outcomes are mixed and dependent on numerous factors that vary between trials. Optimization of DCVs is essential; the selection of GBM-specific antigens and the utilization of 18F-fludeoxyglucose Positron Emission Tomography (FDG-PET) may add significant value and ultimately improve outcomes for patients undergoing treatment for glioblastoma. This review provides an overview of the mechanism of …

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Personal Identity And Particles: The Relativity Of Time, Internal Fluidity, And Social Progress In Orlando, Riley Eyring Oct 2023

Personal Identity And Particles: The Relativity Of Time, Internal Fluidity, And Social Progress In Orlando, Riley Eyring

International Journal of Undergraduate Research and Creative Activities

This essay examines the structural choices Virginia Woolf makes in Orlando to mirror her prose with the relative models of time the protagonist experiences throughout the story. Comparing the leading theories in particle physics at the time Woolf wrote to her work shows that she was aware of these developments and incorporated this knowledge into her writing. Specifically, the relativity of time is used to mirror the relative nature of Orlando’s identity, as they change from man to woman throughout the course of the novel.

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Portland's Keystone Crustacean: Signal Crayfish Behavior, Health, & Habitat In The Tryon Creek Watershed, Kyla Marie Schmitt Oct 2023

Portland's Keystone Crustacean: Signal Crayfish Behavior, Health, & Habitat In The Tryon Creek Watershed, Kyla Marie Schmitt

International Journal of Undergraduate Research and Creative Activities

In the Portland Metro Area, the signal crayfish (Pacifastacus leniusculus) is a keystone species. Signal crayfish consume inaccessible plant matter and detritus, feed various game fish, engineer riverbeds, and are even harvested commercially for human consumption. Recognizing signal crayfishes’ multifaceted ecological and social significance, the purpose of this study was to assess the habitat factors that impact signal crayfish health and behavior in the Tryon Creek Watershed. Data collection revealed that overall, Tryon Creek crayfish were disproportionately likely to be observed in locations with high infrastructure presence levels; substrates composed of silt/sand or a combination of boulders and cobbles; culverts, …

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“Mi Amparo Y Fortaleza”: Seeing Psalms Through A Trans-Iberian Worldview In Espejo Fiel De Vidas (Life’S True Mirror), Catherine Lily Wojda, Joshua Henderson, Matthew Warshawsky Oct 2023

“Mi Amparo Y Fortaleza”: Seeing Psalms Through A Trans-Iberian Worldview In Espejo Fiel De Vidas (Life’S True Mirror), Catherine Lily Wojda, Joshua Henderson, Matthew Warshawsky

International Journal of Undergraduate Research and Creative Activities

This article studies Espejo fiel de vidas (Life’s True Mirror, 1720) of Daniel Israel López Laguna as an example of Baroque Spanish poetry that reworks the book of Psalms for an audience that like the author were conversos, or New Christians, that is, Spanish and Portuguese Catholics of Jewish origin and their descendants. Likewise, it studies the geographic and spiritual journey of one such Iberian New Christian through the Hispano-Portuguese Jewish diaspora who became a practicing Jew upon settling in Jamaica. Besides showing elements of this journey in López Laguna’s paraphrase of Psalms, the article explores how the poet incorporates …

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Differential Expression Analysis For The Identification Of Survival Associated Genes In Primary Bladder Cancer Using Microarray Data, Amos Ochieng Okutse, Kelvin Wangira Nyongesa Oct 2023

Differential Expression Analysis For The Identification Of Survival Associated Genes In Primary Bladder Cancer Using Microarray Data, Amos Ochieng Okutse, Kelvin Wangira Nyongesa

International Journal of Undergraduate Research and Creative Activities

Bladder cancer (BC) is a highly malignant and malevolent tumor whose incidence and mortality worldwide remains high. This paper aimed to identify the differentially expressed genes (DEGs) between normal and primary bladder cancer samples, which might be of prognostic value, and evaluate their association to clinical outcomes (survival) in patients with primary bladder cancer. A sample of 256 gene expression profiles of which 10 were normal bladder mucosae whereas 165 were primary bladder cancer tissues were downloaded from the gene expression omnibus (GEO). The limma package in R was used to perform screening for DEGs after variance reduction through quantile …

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“Scandalously Bifurcated Garments”: Ecocriticism, American Pioneers, And Novelizing Women Of The West, Gillian Gauer, Elizabeth E. Tavares Oct 2023

“Scandalously Bifurcated Garments”: Ecocriticism, American Pioneers, And Novelizing Women Of The West, Gillian Gauer, Elizabeth E. Tavares

International Journal of Undergraduate Research and Creative Activities

While the Western novel is typically associated with cowboys and overarching masculine accomplishments of “settling,” the representation of women’s work beyond narratives of being “tamed” and the settling-down of motherhood has been overlooked by writers and ecocritics alike. Ecofeminist scholarship of the late 1980s and ‘90s, primed to take up such questions, focused primarily on the relationship between women and nature in abstract terms rather than on regionally-specific interpretations. This thesis, therefore, examines the representation of female-identifying protagonists in pioneer narratives of North America in three popular novels of the last century: Zane Grey’s posthumous Woman of the Frontier (1940/1998), …

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Evaluating Social Inclusion: An Adaptable Measure For Use On College Campuses, Kaira L. Bird, Heide D. Island Oct 2023

Evaluating Social Inclusion: An Adaptable Measure For Use On College Campuses, Kaira L. Bird, Heide D. Island

International Journal of Undergraduate Research and Creative Activities

Gender and sexual identity discrimination are commonly reported among persons of non-heterosexual or non-cisgender identities. Sexual and gender minority (SGM) students are more likely to experience discrimination, hate crimes, poverty, sexually transmitted infections, anxiety, and depression compared to heterosexual and cisgender individuals. These marginalized experiences create a unique need for education, resources, support, and community. Greater awareness of sexual and gender minorities encourages college students to feel comfortable sharing their experiences, and openly identifying as a sexual and/or gender minority. Consequently, to retain the full breadth of diversity within university communities, centers on campus that provide programming, education, and advocacy …

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Taking Action Together (Tat): An Annual, Intersectional, Peer-Based Sex Education Program, Micaela C. Frick, Rebecca Schoon Oct 2023

Taking Action Together (Tat): An Annual, Intersectional, Peer-Based Sex Education Program, Micaela C. Frick, Rebecca Schoon

International Journal of Undergraduate Research and Creative Activities

College students are at high risk for experiencing sexual violence. Living without parents, lack of understanding of consent, new relationships, high stress, and experimenting with drugs and alcohol are some factors that increase the risk of sexual violence among college students. Pacific University has existing prevention programs aimed to decrease the incidence of sexual violence, but existing workshops only target first year students and athletes. There is a gap for students who don’t fit in either category. Post-test surveys from these existing prevention programs shows that students favor peer-led workshops. Other sexual violence prevention programs report the benefits of peer-education …

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Lessons As A Prevention Intern: Eliminating Sexual Violence Through School-Based Programs, Emily Spalding, Dawn M. Salgado Oct 2023

Lessons As A Prevention Intern: Eliminating Sexual Violence Through School-Based Programs, Emily Spalding, Dawn M. Salgado

International Journal of Undergraduate Research and Creative Activities

Every 73 seconds another person in America is sexually assaulted. For my senior practicum, I worked at Sexual Assault Resource Center, which provides advocacy and support services, including crisis intervention and counseling, for survivors of sexual violence. My goals for my time with SARC included developing knowledge and skills related to being a trauma therapist, learning about how a nonprofit operates, and gaining an understanding of sex education and sexual violence prevention programs. As a Sexual Assault Advocate and Education and Prevention Intern at SARC, my primary responsibilities involved engaging in community outreach events, delivering educational workshops, and presenting prevention …

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Presence And Abundance Of Antibiotic Resistance Genes At An Organic Goat Dairy Farm, Janice Marie Parks, Noah Askew, Jack Woodrow Creagh-Grave, Gyorgyi Nyerges Oct 2023

Presence And Abundance Of Antibiotic Resistance Genes At An Organic Goat Dairy Farm, Janice Marie Parks, Noah Askew, Jack Woodrow Creagh-Grave, Gyorgyi Nyerges

International Journal of Undergraduate Research and Creative Activities

How does the use of antibiotics in animal husbandry impact antibiotic resistance genes (ARGs) and integron prevalence? This article examines the prevalence of nine ARGs (OXA-2, tetB, tetG, blaCMY-2, ereB, NDM, ermB, sul1, and sul2) and two class one integron sequences (intI1 and CS) at an organic goat dairy farm. To provide insight on how antibiotic use is contributing to the abundance of ARGs and integrons outside of where they are used, we made a comparison between our findings and the prevalence of ARGs and integrons at conventional farms from previously published studies. Samples were collected from an organic goat …

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The Cold Side Of Connectivity: A Journey In The Southern Ocean With Antarctic Fish, Chiara Papetti Oct 2023

The Cold Side Of Connectivity: A Journey In The Southern Ocean With Antarctic Fish, Chiara Papetti

Sustainability Seminar Series

Characterizing connectivity among populations and species differences provides information on distribution of fish biodiversity, dispersal and genetic variability. This information is essential to set conservation priorities, identify scarce management resources and to monitor effectiveness of protection. This information is urgently requested by policymakers evaluating proposals for marine protected areas (MPAs) in Antarctica where fish dominate marine communities and connectivity may be driven by multiple factors affected by climate change. In this talk, I will summarize some recent results on population connectivity of Antarctic fish by looking at hydrodynamics, genetic variability and various life history traits of some species which differ …

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Book Review Essay: Race And Reproduction In Cuba, Zyanya Gutiérrez Oct 2023

Book Review Essay: Race And Reproduction In Cuba, Zyanya Gutiérrez

Journal of International Women's Studies

No abstract provided.

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A Gendered Historical Discourse Of The Naxalbari Movement, Pritha Sarkar Oct 2023

A Gendered Historical Discourse Of The Naxalbari Movement, Pritha Sarkar

Journal of International Women's Studies

This paper analyzes the Indian English novel The Lowland (2012) by Jhumpa Lahiri and examines its representation of the Naxalbari movement’s (1965-1975) gendered history to locate women, their roles, their marginalized position, and the growth of their individual independent identities. The Naxalbari movement is the first major peasant protest within 20 years of Indian independence. Though the first actions of the movement were in a village of North Bengal, this paper mainly concentrates on the movement’s activities after it was urbanized and joined by the middle class. It, therefore, tries to locate the position of middle-class women within the movement. …

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We Deliver: The Condition Of The Woman Academic In India Today, Ananya Dutta Gupta Oct 2023

We Deliver: The Condition Of The Woman Academic In India Today, Ananya Dutta Gupta

Journal of International Women's Studies

This auto-ethnographic essay draws upon Foucault’s Archaeology of Knowledge to discuss the condition of Indian women in the Humanities in academia today. While acknowledging the encouragingly gender-inclusive projections in India’s National Education Policy vision statement from 2020, I argue for more probing engagement with the concrete reality of being a woman teacher and researcher in the increasingly competitive and corporatized milieu of higher education. My methodology has been a close reading of the NEP’s vision statement to analyze recurrences of terms and concepts as pointers to its discursive field. I argue that this policy statement implicitly envisions an empowered new-age …

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Older Women As Active Online Agents: Diversifying Cultural Conceptions Of “Grannies” Through Social Media, Hanna Varjakoski Oct 2023

Older Women As Active Online Agents: Diversifying Cultural Conceptions Of “Grannies” Through Social Media, Hanna Varjakoski

Journal of International Women's Studies

With the advent of social media, the media environment has become more participatory for its users, making it possible for older adults to produce content for social media and be agential in online spaces. This article observes a group of older women known as Activist Grannies (Aktivistimummot in Finnish) and 60+ Finnish women bloggers who identify as “grannies” to discover what kind of agency social media potentially enables for older women. In addition, this article explores the cultural knowledge produced by older women’s self-representations as activist grannies and “granny bloggers.” I demonstrate that social media offers a space to …

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Triumphant Or Trapped Pakistani Women? A Feminist Critique Of Mueenuddin’S “Nawabdin Electrician” And Haq’S Song “Chamkeeli”, Amna Khan Oct 2023

Triumphant Or Trapped Pakistani Women? A Feminist Critique Of Mueenuddin’S “Nawabdin Electrician” And Haq’S Song “Chamkeeli”, Amna Khan

Journal of International Women's Studies

In patriarchal societies, women are traditionally subjugated and suppressed in one way or another. Men are privileged and kept at the center. They speak, express, and dream while benefiting from the autonomy provided to them by the phallogocentric system. By contrast, women are marginalized. Patriarchal writers define women as weak, fragile, helpless, docile, submissive, and emotional. However, this paper reveals that in Daniyal Mueenuddin’s “Nawabdin Electrician” and Abrar-ul-Haq’s song “Chamkeeli,” regardless of a change in times and “gender performativity,” Pakistani male writers continue to stigmatize women. This study shows that although gender roles are changing, women remain subjugated. My paper …

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The Madness Of Women As An Illusional Power In Charlotte Brontë’S Jane Eyre And Fadia Faqir’S Pillars Of Salt, Luma Balaa Oct 2023

The Madness Of Women As An Illusional Power In Charlotte Brontë’S Jane Eyre And Fadia Faqir’S Pillars Of Salt, Luma Balaa

Journal of International Women's Studies

Historically speaking, women have been associated with madness, be it Medea from Ancient Greece, the medieval trials of the witches of Salem, or so called “hysterical” women in the Victorian era. Even in 21st-century literature, arts, and media, the madness of women is widely discussed and often romanticized. Some women authors employed the madwoman trope to show the effects of patriarchal oppression on women. Other studies have associated women’s madness in literature with subversion. This paper, however, claims that the portrayal of madness in both Charlotte Brontë’s Jane Eyre (1847) and Fadia Faqir’s Pillars of Salt (1996) is not subversive, …

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The Racial Swamps Of Reconstruction: Harriet Beecher Stowe’S Life In Post-Civil War Florida, Elif S. Armbruster Oct 2023

The Racial Swamps Of Reconstruction: Harriet Beecher Stowe’S Life In Post-Civil War Florida, Elif S. Armbruster

Journal of International Women's Studies

Harriet Beecher Stowe, the internationally known U.S. author and abolitionist, whom President Abraham Lincoln famously called “the little woman who wrote the book that started this great war,” referring to Uncle Tom’s Cabin (1852) and the American Civil War (1861-1865),[1] was also the author of numerous other works, many of them much lesser known today. Stowe’s Palmetto Leaves (1873), the subject of this essay, was, for example, a best-selling travel narrative about life in Florida after the American Civil War and is considered to have been an impetus behind the modern tourist industry in Florida. Today, however, Palmetto Leaves …

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Tanjungpura Port As An International Hub Port To Improve Economic Competitiveness: An Overview From International Law, Garuda Wiko, Fatma Muthia Kinanti, Muhammad Syafei, Muhammad Rafi Darajati, Adityo Darmawan Sudagung Oct 2023

Tanjungpura Port As An International Hub Port To Improve Economic Competitiveness: An Overview From International Law, Garuda Wiko, Fatma Muthia Kinanti, Muhammad Syafei, Muhammad Rafi Darajati, Adityo Darmawan Sudagung

Indonesian Journal of International Law

The Indonesian Government is currently in the process of developing several new ports in its territory as a means of supporting infrastructure development and maritime connectivity. One of them is the Development of the Kijing Terminal Port in the Province of West Kalimantan. It is important to study international and national legal regulations related to ports and how they affect the development of Tanjungpura Port, Kijing Terminal, which will be directed to become one of the international hub ports in Indonesia. The research methodology employed in this study is normative, with in-concreto legal study approach. It is found …

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Normalized Linearly-Combined Chaotic System: Design, Analysis, Implementation And Application, Md Sakib Hasan, Anurag Dhungel, Partha Sarathi Paul, Maisha Sadia, Md Razuan Hossain Oct 2023

Normalized Linearly-Combined Chaotic System: Design, Analysis, Implementation And Application, Md Sakib Hasan, Anurag Dhungel, Partha Sarathi Paul, Maisha Sadia, Md Razuan Hossain

Faculty and Student Publications

This work presents a general framework for developing a multi-parameter 1-D chaotic system for uniform and robust chaotic operation across the parameter space. This is important for diverse practical applications where parameter disturbance may cause degradation or even complete disappearance of chaotic properties. The wide uninterrupted chaotic range and improved chaotic properties are demonstrated with the aid of stability analysis, bifurcation diagram, Lyapunov exponent (LE), Kolmogorov entropy, Shannon entropy, and correlation coefficient. We also demonstrate the proposed system’s amenability to cascading for further performance improvement. We introduce an efficient Field-Programmable Gate Array (FPGA)-based implementation and validate its chaotic properties using …

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An Investigation Of Black And White College Students’ Knowledge About The Long-Term Effects Of Aces, Nathalie Goubet, Janique Walker, Pamela Moye, Tyler Keohan, Kasey Higgins Oct 2023

An Investigation Of Black And White College Students’ Knowledge About The Long-Term Effects Of Aces, Nathalie Goubet, Janique Walker, Pamela Moye, Tyler Keohan, Kasey Higgins

Psychology Faculty Publications

In the past twenty years, multiple studies have shown the relationship between childhood adversity and later negative health consequences. Yet the extent to which the public is aware of this relationship is unclear. We surveyed Black and White college students about their knowledge of the long-term effects of Adverse Childhood Experiences (ACEs). Students read vignettes comparing children exposed and unexposed to ACEs, and predicted their mental, physical, and social health as adults. Participants were aware of the effect of ACEs on later mental and social health, but not as aware of the risks on physical health. Black and White students …

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