Digital Commons Network^™

Biochar Influences On Phytochemical Composition And Expression Genes Of Curly Kale At Different Treatment Times, Joyce Dedei Anteh, Esraa Almugrabi, Antonina Mostyakova, Olga Timofeeva

Turkish Journal of Botany

his study examined the effect of biochar application to the soil at different times on the phytochemical composition (phenolic compounds, carotenoids, vitamin C, sugars, proteins, MDA, and antioxidant activity) and expression of HCT, F3’H and CHS genes (which are involved in the accumulation of phenolic compounds) in cabbage kale (Brassica oleracea L. var. acephala). Biochar was prepared from chicken manure, using the method of rapid pyrolysis at a temperature of 400 °C. The retention time at the maximum temperature was 4 h, and the heating rate was 10 °C min–1. The biochar fertilizer was applied to 5–7 day-old kale seedlings …

Beta-Carbonic Anhydrase Gene Expression Levels Change Depending On The Drought Severity In Both The Leaves And Roots Of Arabidopsis Thaliana, Sertan Çevi̇k, Oğuzhan Kurt, Ayşi̇n Güzel Değer, Ferit Kocaçinar, Rıza Bi̇nzet

Turkish Journal of Botany

In this study, it was aimed to determine the relationship between β carbonic anhydrase (βCA) gene expression levels and drought stress severity. For this purpose, the expression levels of six βCA genes in the roots and leaves of Arabidopsis thaliana were investigated under mild, moderate, and severe drought conditions. In addition, changes in the biomass, leaf water content, photosynthetic efficiency, CA enzyme activity, free proline content, and lipid peroxidation were also determined. The results showed that all of the β CA gene expression levels and CA enzyme activity increased in the leaf under mild drought conditions; however, the expression levels …

A New Species Of Parasola Section Conopileae (Psathyrellaceae) From Pakistan, Zaman Khan, Muhammad Awais Arshad, Abdul Rehman Niazi, Abdul Nasir Khalid

Turkish Journal of Botany

The genus Parasola is sparsely documented in Pakistan with almost all of its reports from lowlands or northern areas of the country. In this study, we describe a new species, Parasola cinnamomescens, from the Thal Desert, a subtropical region located in Punjab Province, Pakistan. Evidence from morphology and DNA sequence data encompassing the internal transcribed spacer (ITS1-5.8S-ITS2 = ITS) and D1/D2 domain of the large subunit of nuclear ribosomal DNA (28S) reveals that this species is divergent from all previously known species and confirms its placement in Parasola sect. Conopileae. It is recognized by convex to hemispherical or broadly conical …

Distinct Transcriptomic Profiles In Children Prior To The Appearance Of Type 1 Diabetes-Linked Islet Autoantibodies And Following Enterovirus Infection, Jake Lin, Elaheh Moradi, Karoliina Salenius, Suvi Lehtipuro, Tomi Häkkinen, Jutta E Laiho, Sami Oikarinen, Sofia Randelin, Hemang M Parikh, Jeffrey P Krischer, Jorma Toppari, Åke Lernmark, Joseph F Petrosino, Nadim J Ajami, Jin-Xiong She, William A Hagopian, Marian J Rewers, Richard E Lloyd, Kirsi J Rautajoki, Heikki Hyöty, Matti Nykter, Teddy Study Group

Faculty, Staff and Students Publications

Although the genetic basis and pathogenesis of type 1 diabetes have been studied extensively, how host responses to environmental factors might contribute to autoantibody development remains largely unknown. Here, we use longitudinal blood transcriptome sequencing data to characterize host responses in children within 12 months prior to the appearance of type 1 diabetes-linked islet autoantibodies, as well as matched control children. We report that children who present with insulin-specific autoantibodies first have distinct transcriptional profiles from those who develop GADA autoantibodies first. In particular, gene dosage-driven expression of GSTM1 is associated with GADA autoantibody positivity. Moreover, compared with controls, we …

Coregnet: Unraveling Gene Co-Regulation Networks From Public Rna-Seq Repositories Using A Beta-Binomial Statistical Model, Jiasheng Wang, Ying-Wooi Wan, Rami Al-Ouran, Meichen Huang, Zhandong Liu

Faculty, Staff and Students Publications

Millions of RNA sequencing samples have been deposited into public databases, providing a rich resource for biological research. These datasets encompass tens of thousands of experiments and offer comprehensive insights into human cellular regulation. However, a major challenge is how to integrate these experiments that acquired at different conditions. We propose a new statistical tool based on beta-binomial distributions that can construct robust gene co-regulation network (CoRegNet) across tens of thousands of experiments. Our analysis of over 12 000 experiments involving human tissues and cells shows that CoRegNet significantly outperforms existing gene co-expression-based methods. Although the majority of the genes …

Clinical, Genetic And Structural Delineation Of Rpl13-Related Spondyloepimetaphyseal Dysplasia Suggest Extra-Ribosomal Functions Of El1, Prince Jacob, Hillevi Lindelöf, Cecilie F Rustad, Vernon Reid Sutton, Shahida Moosa, Prajna Udupa, Anna Hammarsjö, Gandham Srilakshmi Bhavani, Dominyka Batkovskyte, Kristian Tveten, Ashwin Dalal, Eva Horemuzova, Ann Nordgren, Emma Tham, Hitesh Shah, Else Merckoll, Laura Orellana, Gen Nishimura, Katta M Girisha, Giedre Grigelioniene

Faculty, Staff and Students Publications

Spondyloepimetaphyseal dysplasia with severe short stature, RPL13-related (SEMD-RPL13), MIM#618728), is a rare autosomal dominant disorder characterized by short stature and skeletal changes such as mild spondylar and epimetaphyseal dysplasia affecting primarily the lower limbs. The genetic cause was first reported in 2019 by Le Caignec et al., and six disease-causing variants in the gene coding for a ribosomal protein, RPL13 (NM_000977.3) have been identified to date. This study presents clinical and radiographic data from 12 affected individuals aged 2-64 years from seven unrelated families, showing highly variable manifestations. The affected individuals showed a range from mild to severe short stature, …

Pediatric Hiv+ Kaposi Sarcoma Exhibits Clinical, Virological, And Molecular Features Different From The Adult Disease, Carolina Caro-Vegas, Alice Peng, Angelica Juarez, Allison Silverstein, William Kamiyango, Jimmy Villiera, Casey L Mcatee, Rizine Mzikamanda, Tamiwe Tomoka, Erin C Peckham-Gregory, Razia Moorad, Carrie L Kovarik, Liane R Campbell, Parth S Mehta, Peter N Kazembe, Carl E Allen, Michael E Scheurer, Nmazuo W Ozuah, Dirk P Dittmer, Nader Kim El-Mallawany

Center for Medical Ethics and Health Policy Staff Publications

BACKGROUND

Kaposi sarcoma (KS) is among the most common childhood cancers in Eastern and Central Africa. Pediatric KS has a distinctive clinical presentation compared with adult KS, which includes a tendency for primary lymph node involvement, a considerable proportion of patients lacking cutaneous lesions, and a potential for fulminant disease. The molecular mechanisms or correlates for these disease features are unknown.

METHODS

This was a cross-sectional study. All cases were confirmed by IHC for KS-associated herpesvirus (KSHV) LANA protein. Baseline blood samples were profiled for HIV and KSHV genome copy numbers by qPCR and secreted cytokines by ELISA. Biopsies were …

Nonlinear Model Predictive Control Of Vagal Nerve Stimulation To Regulate Hemodynamic Variables, Oluwasanmi Adeodu, Michelle Gee, Babak Mahmoudi, Rajanikanth Vadigepalli, Mayuresh Kothare

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Various pre-clinical investigations indicate that the electrical stimulation of the cervical branch of the vagus that innervates the heart has therapeutic value in the management of various cardiac diseases. In theory, the design of a closed-loop control mechanism that automatically adjusts vagal nerve stimulation (VNS) parameters based on real-time physiological feedback can eliminate intra-patient variability in VNS outcomes and therefore represents a major step towards patient-specific therapy. This study develops a nonlinear model predictive control (NMPC) approach for VNS of a pulsatile, human cardio-baroreflex system. The manipulated variables are the frequency and amplitude of a charge-balanced biphasic current. The effects …

Compact 3u As A Novel Artificial Lighting Source For Gloxinia (Sinningia Spp.) And Potato (Solanum Tuberosum) Micropropagation, Ajstd Editorialboard

ASEAN Journal on Science and Technology for Development

No abstract provided.

Effects Of Habitat Fragmentation On Genetic Diversity In Cycas Balansae (Cycadaceae), Ajstd Editorialboard

ASEAN Journal on Science and Technology for Development

No abstract provided.

Effectiveness Of Selected Entomopathogenic Fungi In Packed Rice Grain At Room Temperature Against Corcyra Cephalonica Stainton, Ajstd Editorialboard

ASEAN Journal on Science and Technology for Development

No abstract provided.

Recycled Pet For Rice Husk/Polyester Composites, Ajstd Editorialboard

ASEAN Journal on Science and Technology for Development

No abstract provided.

Studies On Fucoidan And Its Production From Vietnamese Brown Seaweeds, Ajstd Editorialboard

ASEAN Journal on Science and Technology for Development

No abstract provided.

Marine Natural Products And Their Potential Application In The Future, Ajstd Editorialboard

ASEAN Journal on Science and Technology for Development

No abstract provided.

Medium Optimization For The Production Of Biomass By Cunninghamella Sp. 2a1 Using Response Surface Methodology, Ajstd Editorialboard

ASEAN Journal on Science and Technology for Development

No abstract provided.

The Effects Of Engineering Summer Camps On Middle And High School Students’ Engineering Interest And Identity Formation: A Multi-Methods Study, Timothy Robinson, Adam Kirn, Jenny Amos, Indira Chatterjee

Journal of Pre-College Engineering Education Research (J-PEER)

This multi-methods study explores changes in engineering interest and identity of middle and high school students (n = 79) attending introductory-level engineering summer camps at a large western land grant university. Middle school is a critical time when student interest, identity, and subsequently career choice begin to emerge and hence it is important that at this age students are given accurate information about engineering majors in college and future career opportunities in engineering. Data were collected over a period of two years in six summer camps. Three separate populations of middle and high school students participated in the summer …

Evangelical Hospital Association Report, 1981, Advocate Aurora Health

Historical Documents - Combined

Evangelical Hospital Association, Oak Brook, IL: Annual report of the Evangelical Hospital Association. Includes data from legacy hospitals: Christ Hospital, Good Samaritan Hospital, Good Shepherd Hospital, and the Evangelical School of Nursing. This report also celebrates the 75th anniversary of the Evangelical Hospital Association.

The complete financial statements can be found as a supplemental file.

Exploring Public School K-12 Educators’ Experiences With The Special Education Eligibility Process For African American/Black And Hispanic/Latino Students In Rural Communities, Debra R. Gately

Doctor of Education Program Dissertations

Rural school districts often face unique challenges such as limited resources, attracting and retaining qualified teachers, and varied offerings of professional development opportunities and training. This study substantiated these challenges and revealed the challenges presented when educators do not consider the cultural and linguistic factors that exist among the student population when considering academic and behavioral interventions. This qualitative investigation explored how general education teachers in a public school district in the northeastern United States experienced the special education eligibility process for African American/Black and Hispanic/Latino students in a rural community. Guided by the theories of intersectionality and systems view …

Vascum Muricatum - Caribbean Vase Snail, Jason E. Rosales, Amy Hirons Dr

Hirons Field Techniques

Acquired from the sandy beaches of South Florida, this is a shell of the Caibbean Vase snail otherwise known as Vasum murictum. Collected by Jason Rosales on 05/12/22.

Investigation Of Electron Transfer In The Ksha-Kshb-R286a Protein Complex From Mycobacterium Tuberculosis, Elyse Tavares

Honors Program Theses and Projects

With drug-resistant bacteria such as Mycobacterium tuberculosis being a serious public health problem, infected individuals have minimal treatment options. By investigating the electron transfer within 3-ketosteroid-9��-hydroxylase (KshAB), a protein involved in the energy production pathway of this bacteria, it will allow for potential inhibitors of this enzyme to be designed as antibiotics against tuberculosis. The purpose of this project is to stop the interaction between the KshA and KshB complexes to prevent the bacteria from gaining energy by breaking down steroids like cholesterol. To achieve this goal, an arginine at the 286th position of the KshB protein was mutated to …

A Comparative Study On The Rheological Properties Of Upper Convected Maxwell Fluid Along A Permeable Stretched Sheet, Sara I. Abdelsalam, W. Abbas, A. M. Megahed, A. M. Said

Basic Science Engineering

The objective of this paper is to examine the flow of a non-Newtonian Maxwell fluid induced by a permeable stretching sheet in motion within a porous medium. The research incorporates the Cattaneo-Christov heat flux model to study the heat transfer process. The utilization of the Cattaneo-Christov heat flux approach becomes relevant in scenarios involving materials with high thermal conductivity or during short time intervals. Consequently, the current investigation holds significant importance. It is assumed that the viscosity of the Maxwell fluid changes exponentially as the temperature changes. The modeling of the physical phenomena being investigated takes into account the effects …

How To Celebrate Food-Centered Holidays Through Disordered Eating Recovery, Anna Jones

Browse All News

No abstract provided.

Ictalurus Punctatus (Channel Catfish) Neurocranium, Kayla D. Jones, Maura P. Wondra, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from 9.70 cm total length (TL) Ictalurus punctatus (Channel Catfish), collected from Davie, Florida in June 2023 by Katrina Sawickij.

Clostridioides Difficile Spores Tolerate Disinfection With Sodium Hypochlorite Disinfectant And Remain Viable Within Surgical Scrubs And Gown Fabrics, Humaira Ahmed, Lovleen Tina Joshi

Peninsula Dental School

Clostridioides difficile is the most common cause of antibiotic-associated diarrhoea globally. Its spores have been implicated in the prevalence of C. difficile infection due to their resistance and transmission ability between surfaces. Currently, disinfectants such as chlorine-releasing agents (CRAs) and hydrogen peroxide are used to decontaminate and reduce the incidence of infections in clinical environments. Our previous research demonstrated the ability of C. difficile spores to survive exposure to recommended concentrations of sodium dichloroisocyanurate in liquid form and within personal protective fabrics such as surgical gowns; however, the present study examined the spore response to clinical in-use concentrations of sodium …

Multi-View Information Fusion Using Multi-View Variational Autoencoder To Predict Proximal Femoral Fracture Load, Chen Zhao, Joyce H. Keyak, Xuewei Cao, Qiuying Sha, Li Wu, Zhe Luo, Lan Juan Zhao, Qing Tian, Michael Serou, Chuan Qiu, Kuan Jui Su, Hui Shen, Hong Wen Deng, Weihua Zhou

Michigan Tech Publications

Background: Hip fracture occurs when an applied force exceeds the force that the proximal femur can support (the fracture load or “strength”) and can have devastating consequences with poor functional outcomes. Proximal femoral strengths for specific loading conditions can be computed by subject-specific finite element analysis (FEA) using quantitative computerized tomography (QCT) images. However, the radiation and availability of QCT limit its clinical usability. Alternative low-dose and widely available measurements, such as dual energy X-ray absorptiometry (DXA) and genetic factors, would be preferable for bone strength assessment. The aim of this paper is to design a deep learning-based model to …

Spartan Daily, November 21, 2023, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2023

Volume 161, Issue 39

Demographic History Shapes North American Gray Wolf Genomic Diversity And Informs Species' Conservation, Bridgett M. Vonholdt, Daniel R. Stahler, Kristin Brzeski, Marco Musiani, Rolf O. Peterson, Michael Phillips, John Stephenson, Kent Laudon, Erin Meredith, John A. Vucetich, Jennifer A. Leonard, Robert K. Wayne

Michigan Tech Publications

Effective population size estimates are critical information needed for evolutionary predictions and conservation decisions. This is particularly true for species with social factors that restrict access to breeding or experience repeated fluctuations in population size across generations. We investigated the genomic estimates of effective population size along with diversity, subdivision, and inbreeding from 162,109 minimally filtered and 81,595 statistically neutral and unlinked SNPs genotyped in 437 grey wolf samples from North America collected between 1986 and 2021. We found genetic structure across North America, represented by three distinct demographic histories of western, central, and eastern regions of the continent. Further, …

Bearded Or Smooth? Awns Improve Yield When Wheat Experiences Heat Stress During Grain Fill In The Southeastern United States, Noah Dewitt, Jeanette Lyerly, Mohammed Guedira, James B. Holland, J. Paul Murphy, Brian P. Ward, Richard E. Boyles, Mohamed Mergoum, Md Ali Babar, Ehsan Shakiba, Russel Sutton, Amir Ibrahim, Vijay Tiwari, Nicholas Santantonio, David A. Van Sanford, Kimberly Howell, Jared H. Smith, Stephen A. Harrison, Gina Brown-Guedira

Faculty Publications

The presence or absence of awns-whether wheat heads are 'bearded' or 'smooth' - is the most visible phenotype distinguishing wheat cultivars. Previous studies suggest that awns may improve yields in heat or water-stressed environments, but the exact contribution of awns to yield differences remains unclear. Here we leverage historical phenotypic, genotypic, and climate data for wheat (Triticum aestivum) to estimate the yield effects of awns under different environmental conditions over a 12-year period in the southeastern USA. Lines were classified as awned or awnless based on sequence data, and observed heading dates were used to associate grain fill periods of …

Multi-Omics Reveals Largely Distinct Transcript- And Protein-Level Responses To The Environment In An Intertidal Mussel, Lani U. Gleason, Florian J. Fekete, Richelle L. Tanner, W. Wesley Dowd

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Organismal responses to stressful environments are influenced by numerous transcript- and protein-level mechanisms, and the relationships between expression changes at these levels are not always straightforward. Here, we used paired transcriptomic and proteomic datasets from two previous studies from gill of the California mussel, Mytilus californianus, to explore how simultaneous transcript and protein abundance patterns may diverge under different environmental scenarios. Field-acclimatized mussels were sampled from two disparate intertidal sites; individuals from one site were subjected to three further treatments (common garden, low-intertidal or high-intertidal outplant) that vary in temperature and feeding time. Assessing 1519 genes shared between …

Prospective Considerations For Suicide Preventative Dietetics Practice: A Narrative Review, William Charles Fite

Electronic Theses and Dissertations Archive

This narrative review draws connections between the scope of practice of Registered Dietitians and issues related to suicide risk. It covers literature on topics including nutrition science (divided into biomarkers, micronutrients, and microbiome), dietary pattern, food insecurity, eating disorders, and chronic illnesses. Articles were collected from three databases: PubMed, SCOPUS, and CINAHL Complete. They were then saved to a citation manager and screened, with additional screening being performed following export to Excel documents, with n = 61 being included. Altered lipid metabolism, thyroid markers, and fasting blood glucose may be associated with suicide risk. Diet composition, along with nutrient deficiencies, …