Digital Commons Network^™

The Use Of Meditation/Mindfulness To Improve Anxiety In Young Adults, Aaron Wilkerson

Master of Science in Nursing Family Nurse Practitioner

Without intervention and relief from stress and anxiety, it can cause physical, psychological, and behavioral abnormalities (Kim et al., 2018). Chronic stress has been found to be prevalent among young adult age, students, and is having lasting negative effects on mental, emotional, and physical health, including feelings of being overwhelmed, hopelessness, loneliness, and even suicidal ideation (Burgstahler & Stenson, 2020). The practice of meditation and mindfulness offers a non-pharmacological option over the typical standard-of-care pharmacological treatment and provides a life skill for young adults to manage their stress and anxiety, ultimately overall improving their mental health (Lemay et al., 2019). …

Understanding Marsh Elevation And Accretion Processes And Vulnerability To Rising Sea Levels Across Climatic And Geomorphic Gradients In California, Usa, Karen M. Thorne, Mckenna L. Bristow, Lyndsay L. Rankin, Katya E. Kovalenko, Justine A. Neville, Chase M. Freeman, Glenn R. Guntenspergen

State & Federal Reports and Publications

Tidal marshes build elevations by below- and aboveground organic and mineral soil processes. Marsh elevation and accre- tion data can be used to determine if marshes are keeping pace with sea-level rise. Using a network of 54 deep rod surface elevation tables with paired feldspar marker horizon plots, we tracked elevation and accretion trends across 16 marshes in California, USA. All sites had overall positive gains across years that included severe drought conditions and extreme rain events. Marsh elevation relative to tidal datum (z*) was the key predictor for elevation and accretion rates, with higher change rates at lower z* …

Port Hamilton Refining And Transportation Lllp V. Epa

2023 Decisions

Agency

The "Nonministerial" Exception, Athanasius G. Sirilla

Notre Dame Law Review

In 2014, Charlotte Catholic High School declined to continue Lonnie Billard’s employment as a substitute drama teacher after he publicly announced, via Facebook, that he and his same-sex partner were getting civilly married. Billard sued the school in the Western District of North Carolina for unlawful employment discrimination under Title VII of the Civil Rights Act due to his sexual orientation. The district court granted summary judgment in favor of Billard. The court first held that the high school’s actions could constitute unlawful sex discrimination in light of the Supreme Court’s ruling in Bostock v. Clayton County. The district court …

Jackfish (Caranx Lugubris) Neurocranium, Lauren Groves, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from 9 cm total length (TL) Jackfish, Caranx lugubris, collected from Ideal Market on September 18th, by Lauren Groves

Regulation Of Regeneration In Arabidopsis Thaliana, Md Khairul Islam, Sai Teja Mummadi, Sanzhen Liu, Hairong Wei

Michigan Tech Publications

We employed several algorithms with high efficacy to analyze the public transcriptomic data, aiming to identify key transcription factors (TFs) that regulate regeneration in Arabidopsis thaliana. Initially, we utilized CollaborativeNet, also known as TF-Cluster, to construct a collaborative network of all TFs, which was subsequently decomposed into many subnetworks using the Triple-Link and Compound Spring Embedder (CoSE) algorithms. Functional analysis of these subnetworks led to the identification of nine subnetworks closely associated with regeneration. We further applied principal component analysis and gene ontology (GO) enrichment analysis to reduce the subnetworks from nine to three, namely subnetworks 1, 12, and 17. …

Brha, Kevin Rafferty, Briana K. Zaffiro, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Skull from Broad-winged Hawk (Buteo platypterus).

2023-11-22 To Pay Or Not To Pay: Seattle Public Transit, Bridget Lawrence

The Spectator Online

No abstract provided.

N6-Methyladenosine-Mediated Overexpression Of Long Noncoding Rna Adamts9-As2 Triggers Neuroblastoma Differentiation Via Regulating Lin28b/Let-7/Mycn Signaling, Yun Liu, Jun Zhang, Fang Cao, Xiaobao Dong, Jie Li, Yanna Cao, Zhanglin Li, Yan Guo, Jie Yan, Yuanyuan Liu, Qiang Zhao

Faculty, Staff and Student Publications

Neuroblastomas have shed light on the differentiation disorder that is associated with spontaneous regression or differentiation in the same tumor at the same time. Long noncoding RNAs (lncRNAs) actively participate in a broad spectrum of biological processes. However, the detailed molecular mechanisms underlying lncRNA regulation of differentiation in neuroblastomas remain largely unknown. Here, we sequenced clinical samples of ganglioneuroma, ganglioneuroblastoma, and neuroblastoma. We compared transcription profiles of neuroblastoma cells, ganglion cells, and intermediate state cells; verified the profiles in a retinoic acid-induced cell differentiation model and clinical samples; and screened out the lncRNA ADAMTS9 antisense RNA 2 (ADAMTS9-AS2), which contributed …

The Impact Of Environmental Factors And Management On The Fitness Of Carlina Acaulis Subsp. Caulescens (Lam.) Schübl. Et G. Martens In Mountain Mesic Meadows, Daniel Pruchniewicz, Ȃngela Lomba, Ludwik Żołnierz, Agnieszka Dradrach, João Pradinho Honrado

Turkish Journal of Botany

The stemless carline thistle (Carlina acaulis subsp. caulescens) is a plant species commonly found at lower altitudes in the Central European mountains. Although it is still relatively frequent in the area, there has been a decrease in its numbers in the last decades. This research aims to determine the impact of the management of mountain mesic meadows and habitat factors on the morphometric variability of C. acaulis and species composition patterns of accompanying vegetation. The study was carried out in the central part of the Sudetes Mountains (SW Poland) on a network of 42 plots randomly established within mesic grasslands. …

Influence Of Rootstock Age And Gibberellin On The Survival Rate Of Clove (Syzygium Aromaticum L. Merr. & Perr.) Grafting, Ireng Darwati, Rudi Suryadi, Nurliani Bermawie, Octivia Trisilawati, Devi Rusmin, Sri Wahyuni, Siswanto Siswanto, R Vitri Garvita

Turkish Journal of Botany

Clove (Syzygium aromaticum) is a cross-pollinated crop with significant genetic variation in planting materials derived from seeds. Vegetative propagation through grafting is a valuable strategy to achieve genetically identical characteristics in progeny. This study investigates the influence of rootstock age and hormone (gibberellin) treatments on the grafting union and survival rate of top clove grafting under greenhouse conditions. The experiments followed a randomized block design with three replications, each containing 10 samples, and involving two factors: rootstock age (4, 6, and 8 weeks old) and gibberellin (GA3 ) concentrations (0 and 1 mg L–1). The variables observed include success percentage, …

Northern Red Snapper (Lutjanus Campechnus) Neurocranium, Ajani K. Saldana, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from 7.5 cm total length (TL) 37 cm Lutjanus campechanus (Northern Red Snapper), collected from Mango Tree Supermarket in September 2023 by Ajani Saldana

Blsk 3d Scan, Kevin Rafferty, Briana K. Zaffiro, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Skull from Black Skimmer (Rhnchops niger)

Genome-Wide Identification Of Qtls Associated With Iron Deficiency Tolerance In Soybean Reveals Gata12 As The Integrator Of Iron Signaling In Roots, Amir Maqbool, Ahmet Şahi̇n, Allah Bakhsh, Emre Aksoy

Turkish Journal of Botany

Iron (Fe) is an essential micronutrient required for plant growth and development. However, its deficiency causes substantial yield losses, particularly in alkaline soils. Soybean (Glycine max) serves as an ideal model to study Fe deficiency chlorosis (IDC) due to its inefficient Fe uptake from the soil. Although the quantitative trait loci (QTL) associated with IDC tolerance were determined in soybean, the specific genes within these QTL regions remain unidentified. In this study, it was aimed to identify and analyze the expression levels of genes present in IDC-responsive soybean QTL under Fe deficiency. Through this investigation, 6593 genes were identified within …

Engineering Virtuous Health Habits Using Emotion And Neurocognition: Flexibility For Lifestyle Optimization And Weight Management (Even Flow), Patrick J. Smith, Heather E. Whitson, Rhonda M. Merwin, C. Virginia O'Hayer, Timothy J. Strauman

Department of Psychiatry and Human Behavior Faculty Papers

Interventions to preserve functional independence in older adults are critically needed to optimize 'successful aging' among the large and increasing population of older adults in the United States. For most aging adults, the management of chronic diseases is the most common and impactful risk factor for loss of functional independence. Chronic disease management inherently involves the learning and adaptation of new behaviors, such as adopting or modifying physical activity habits and managing weight. Despite the importance of chronic disease management in older adults, vanishingly few individuals optimally manage their health behavior in the service of chronic disease stabilization to preserve …

Pollen Morphology Of Scabiosa L. And Lomelosia Raf. (Caprifoliaceae) Taxa In Türkiye, Ahmet Aksoy, Bayram Atasagun

Turkish Journal of Botany

Pollen morphology of 34 taxa belonging to genera Scabiosa and Lomelosia were investigated using a light microscope (LM) and scanning electron microscopy (SEM). Pollen grains of Scabiosa and Lomelosia taxa are tricolpate and triporate, respectively. Pollen shapes vary from oblate to prolate. The exine surface ornamentation can be divided into five types, namely echinate, echinatemicroechinate, echinate-gemmate, echinate-microechinate/gemmate and microechinate-gemmate. Pollen grain sizes were classified as very large in three species of Lomelosia and large in the rest. Statistical analyses revealed some quantitative morphological features, such as equatorial axes, L (polar view amb), and t (apocolpium) as the primary characters for …

Trichoderma Indica: A New Species In The Longibrachiatum Clade From Western Ghats, India, Ajay Lagashetti, Sanjay Singh, Paras Nath Singh

Turkish Journal of Botany

Trichoderma is a hyperdiverse genus that comprises species showing a wide range of applications. In this study, we have found an isolate of the genus Trichoderma from a soil sample collected from Vetal Hill, Pune, Maharashtra State, India. The isolate was found to be morphologically distinct compared to other isolates of the Longibrachiatum clade showing longer phialides and shorter conidia. Moreover, a phylogenetic analysis based on combined sequence data of the second-largest nuclear RNA polymerase subunit (rpb2), and the translation elongation factor 1-α (tef1-α) confirmed the uniqueness of the present isolate, showing an independent branch supported by strong bootstrap values …

Patterns Of Utilization And Clinical Adoption Of 0.35 Tesla Mr-Guided Radiation Therapy In The United States - Understanding The Transition To Adaptive, Ultra-Hypofractionated Treatments, Michael Chuong

All Publications

Purpose/objective: Magnetic resonance-guided radiation therapy (MRgRT) utilization is rapidly expanding worldwide, driven by advanced capabilities including continuous intrafraction visualization, automatic triggered beam delivery, and on-table adaptive replanning (oART). Our objective was to describe patterns of 0.35Tesla(T)-MRgRT (MRIdian) utilization in the United States (US) among early adopters of this novel technology.

Materials/methods: Anonymized administrative data from all US MRIdian treatment systems were extracted for patients completing treatment from 2014 to 2020. Detailed treatment information was available for all MRIdian linear accelerator (linac) systems and some cobalt systems.

Results: Seventeen systems at 16 centers delivered 5736 courses and 36,389 fractions (fraction details …

Glial Cell Adhesion Molecule (Glialcam) Determines Proliferative Versus Invasive Cell States In Glioblastoma, Arpan De, John M Lattier, John E Morales, Jack R Kelly, Xiaofeng Zheng, Zhihua Chen, Sumod Sebastian, Zahra Nassiri Toosi, Jason T Huse, Frederick F Lang, Joseph H Mccarty

Faculty, Staff and Student Publications

The malignant brain cancer glioblastoma (GBM) contains groups of highly invasive cells that drive tumor progression as well as recurrence after surgery and chemotherapy. The molecular mechanisms that enable these GBM cells to exit the primary mass and disperse throughout the brain remain largely unknown. Here we report using human tumor specimens and primary spheroids from male and female patients that glial cell adhesion molecule (GlialCAM), which has normal roles in brain astrocytes and is mutated in the developmental brain disorder megalencephalic leukoencephalopathy with subcortical cysts (MLC), is differentially expressed in subpopulations of GBM cells. High levels of GlialCAM promote …

Prospective Relationship Between Co-Rumination And Depressive Symptoms In Early Adolescence: Brooding Rumination As A Mechanism, Katherine S. Benjamin

Clinical Psychology Dissertations

Adolescence is a developmental period during which there is a significant increase in depressive symptoms. Both interpersonal and intrapersonal emotion regulation strategies, including co-rumination and rumination, contribute to the development of depressive symptoms. However, there has been relatively little research investigating the connections between co-rumination and rumination and their associations with depression. Theories of depression, such as interpersonal theories and Response Styles Theory suggest that both relational processes and the ways in which an individual responds internally may promote and maintain depressive symptoms. The current study examined whether brooding rumination serves as the mechanism explaining the relationship between co-rumination and …

Advances In Melanoma: Epidemiology, Diagnosis, And Prognosis, Shayan Waseh, Jason B. Lee

Department of Dermatology and Cutaneous Biology Faculty Papers

Unraveling the multidimensional complexities of melanoma has required concerted efforts by dedicated community of researchers and clinicians battling against this deadly form of skin cancer. Remarkable advances have been made in the realm of epidemiology, classification, diagnosis, and therapy of melanoma. The treatment of advanced melanomas has entered the golden era as targeted personalized therapies have emerged that have significantly altered the mortality rate. A paradigm shift in the approach to melanoma classification, diagnosis, prognosis, and staging is underway, fueled by discoveries of genetic alterations in melanocytic neoplasms. A morphologic clinicopathologic classification of melanoma is expected to be replaced by …

The Implications Of Ferroptosis In Antibiotic Resistance, Marysol Hohl

Senior Honors Theses

Bacterial infections in the United States are becoming increasingly resistant to existing antibiotic treatments. Due to projected increases in resistance and the recent decrease in novel antibacterials, experts have determined that the United States is in the “post-antibiotic era.” The scientific community has failed to resolve resistance despite the continual discovery of new antibiotic compounds. In the past decade, a novel form of cell death called ferroptosis has been implicated in antibiotic treatment by employing the use of nanotechnology. This literature review will describe the problem of bacterial resistance and demonstrate how current research is pioneering a new age of …

Clinical, Genetic And Structural Delineation Of Rpl13-Related Spondyloepimetaphyseal Dysplasia Suggest Extra-Ribosomal Functions Of El13, Prince Jacob, Hillevi Lindelöf, Cecilie F Rustad, Vernon Reid Sutton, Shahida Moosa, Prajna Udupa, Anna Hammarsjö, Gandham Srilakshmi Bhavani, Dominyka Batkovskyte, Kristian Tveten, Ashwin Dalal, Eva Horemuzova, Ann Nordgren, Emma Tham, Hitesh Shah, Else Merckoll, Laura Orellana, Gen Nishimura, Katta M Girisha, Giedre Grigelioniene

Faculty, Staff and Students Publications

Spondyloepimetaphyseal dysplasia with severe short stature, RPL13-related (SEMD-RPL13), MIM#618728), is a rare autosomal dominant disorder characterized by short stature and skeletal changes such as mild spondylar and epimetaphyseal dysplasia affecting primarily the lower limbs. The genetic cause was first reported in 2019 by Le Caignec et al., and six disease-causing variants in the gene coding for a ribosomal protein, RPL13 (NM_000977.3) have been identified to date. This study presents clinical and radiographic data from 12 affected individuals aged 2-64 years from seven unrelated families, showing highly variable manifestations. The affected individuals showed a range from mild to severe short stature, …

Dopamine, Norepinephrine And Serotonin Participate Differently In Methylphenidate Action In Concomitant Behavioral And Ventral Tegmental Area, Locus Coeruleus And Dorsal Raphe Neuronal Study In Young Rats, Cruz Reyes-Vasquez, Zachary Jones, Bin Tang, Nachum Dafny

Faculty, Staff and Student Publications

Methylphenidate (MPD), known as Ritalin, is a psychostimulant used to treat children, adults, and the elderly. MPD exerts its effects through increasing concentrations of dopamine (DA), norepinephrine (NE), and serotonin (5-HT) in the synaptic cleft. Concomitant behavioral and neuronal recording from the ventral tegmental area (VTA), locus coeruleus (LC), and from the dorsal raphe (DR) nucleus, which are the sources of DA, NE, and 5-HT to the mesocorticolimbic circuit, were investigated following acute and repetitive (chronic) saline, 0.6, 2.5, or 10.0 mg/kg MPD. Animals received daily saline or MPD administration on experimental days 1 to 6 (ED1–6), followed by a …

Barriers To The Diagnosis, Care, And Management Of Pediatric Patients With Ehlers-Danlos Syndrome In The United States: A Qualitative Analysis., William R. Black, Lora L. Black, Jordan T. Jones

Manuscripts, Articles, Book Chapters and Other Papers

Objectives: Ehlers-Danlos Syndromes (EDS) are a family of heritable connective tissue diseases. Primary practitioners are capable of diagnosing and managing EDS; however, few are knowledgeable and comfortable enough to see patients with EDS, resulting in delays in diagnosis and care. This study explores the barriers physicians experience with diagnosing, managing, and caring for patients with EDS, and potential resolutions to those barriers. Methods: As part of a larger online study, providers (n = 107) in the United States were asked to specify "What information would improve (their) comfort" in diagnosing, caring for, and managing EDS via open-ended questions. Results …

Tidal Bed Stress Asymmetry And Sediment Transport In Estuaries, Austin Scott Hudson

Dissertations and Theses

Rivers and estuaries provide numerous ecological, economic, and cultural resources. The value of these resources is greatly influenced by sediment transport processes, which can be affected by human activities and climate variability. A key driver of sediment transport in tidal rivers and estuaries is tidal asymmetry of velocity and bed stress, which can manifest from both non-linear tidal interactions and linear interactions among astronomical tidal constituents.

In this study, an analytical framework is developed to examine and describe the dynamics of bed stress asymmetry in semidiurnal, diurnal, and mixed-tide estuaries (Chapter 1). While tidal velocity asymmetry has been previously analyzed, …

Hyperleptinemia Contributes To Antipsychotic Drug-Associated Obesity And Metabolic Disorders, Shangang Zhao, Qian Lin, Wei Xiong, Li Li, Leon Straub, Dinghong Zhang, Rizaldy Zapata, Qingzhang Zhu, Xue-Nan Sun, Zhuzhen Zhang, Jan-Bernd Funcke, Chao Li, Shiuhwei Chen, Yi Zhu, Nisi Jiang, Guannan Li, Ziying Xu, Steven C Wyler, May-Yun Wang, Juli Bai, Xianlin Han, Christine M Kusminski, Ningyan Zhang, Zhiqiang An, Joel K Elmquist, Olivia Osborn, Chen Liu, Philipp E Scherer

Faculty, Staff and Students Publications

Despite their high degree of effectiveness in the management of psychiatric conditions, exposure to antipsychotic drugs, including olanzapine and risperidone, is frequently associated with substantial weight gain and the development of diabetes. Even before weight gain, a rapid rise in circulating leptin concentrations can be observed in most patients taking antipsychotic drugs. To date, the contribution of this hyperleptinemia to weight gain and metabolic deterioration has not been defined. Here, with an established mouse model that recapitulates antipsychotic drug-induced obesity and insulin resistance, we not only confirm that hyperleptinemia occurs before weight gain but also demonstrate that hyperleptinemia contributes directly …

Cover And Contents

Turkish Journal of Botany

No abstract provided.

Ethnobotany Of Medicinal Plants Used In Dermatology In Türkiye: A Review, Serpi̇l Demi̇rci̇ Kayiran, Meryem Parlak, Di̇dem Yilmaz Oral

Turkish Journal of Botany

Medicinal plants are increasingly used to treat skin diseases and as cosmetics. Türkiye has a rich diversity of medicinal flora, and patients have a choice of ethnomedicines to manage various dermatology problems. This comprehensive review aims to summarize the primary information available on the dermatological properties of medicinal plants in Türkiye and provide a baseline for the detection of new plant species having efficacy against skin conditions. In this review, clinical and experimental data were researched using relevant search terms in scientific literature databases like PubMed, Web of Science, Google Scholar, ScienceDirect, Scopus, EBSCO, ProQuest, Cochrane Library, and HighWire Press. …

A Comprehensive Ethnobotanical Survey Of Medicinal Plants For 80 Villages In Trabzon (Türkiye), Sila Ozlem Sener, Kami̇l Çoşkunçelebi̇, Sali̇h Terzi̇oğlu, Aleyna Nalçaoğlu, Tuğçe Peli̇n Gençkaya, Ufuk Özgen, Merve Yüzbaşioğlu Baran

Turkish Journal of Botany

The current study targeted to perform qualitative and quantitative analysis of medicinal plant taxa used in folk medicine in Trabzon. Due to its historical significance, diversity of plant species, and hosting a wide range of cultures, the Turkish city of Trabzon has significant ethnobotanical potential. Ethnobotanical data including family name, scientific name, local name, used parts, therapeutic uses, preparation methods, administration routes, and cited locations were gathered by face-to-face interviews with 645 participants mostly over 50 years old. The quantitative analyses were executed by the determination of frequency values of citation (FC), use value (UV), fidelity level (FL), and informant …