Digital Commons Network^™

Getting Beyond “Craap”: Scientific Literacy In Fyw And Wad, Erica Duran, Lauren M. Springer

The Journal of the Assembly for Expanded Perspectives on Learning

While first-year writing (FYW) programs often bear the responsibility for teaching students to write across the disciplines (Downs and Wardle), too often students restrict the concepts learned in FYW to the humanities, or even worse, a single class. Moreover, students frequently complete research assignments in FYW which restrict them to scholarly or peer-reviewed sources, hindering their ability to learn how to assess popular sources. This can be especially problematic with scholarly STEM sources, which are laden with unfamiliar technical terms. Although the writing and research skills learned in FYW are often intended to be interdisciplinary, FYW faculty have opportunities to …

Negotiating Scientific Identity And Agency: Graduate Student Perspectives On A Public Communication Of Science Course, Lilly Campbell

The Journal of the Assembly for Expanded Perspectives on Learning

Drawing on interviews with nine graduate science students, this article explores perspectives on a Public Communication of Science (PCS) course designed to help students translate their research for a public talk given at a local town hall. I first outline the history of the student-run course and then discuss three course components—public rhetoric of science; improvisation; and audience awareness. Within each component, I describe one student’s particular experience with the course. I describe how students transferred rhetorical lessons from the course to their academic writing but could also transfer rigid views of communication from their scientific work back into their …

Contributors To Jaepl, Vol. 28, Wendy Ryden

The Journal of the Assembly for Expanded Perspectives on Learning

List of contributors and biographies for JAEPL, Volume 28.

Cancer Risk In Human Spaceflight And Directions For Space Nursing: A Rapid Scoping Review, Brighton Blaze Krejci

Honors Capstone Projects and Theses

No abstract provided.

Stream Restoration Effectiveness In Mullins Creek In Fayetteville, Arkansas, Amadeo Scott

Crop, Soil and Environmental Sciences Undergraduate Honors Theses

Lotic waterways are vital for habitat, food, water, and flood protection, but urbanization poses a major threat to their integrity. Runoff from urban surfaces leads to pollution, flashiness, loss of biodiversity, and other symptoms, also known as Urban Stream Syndrome (USS). To combat USS, streams can be restored, but most restorations are not monitored so their long-term effectiveness is unknown. This study quantitatively evaluated a decade-old stream restoration in Fayetteville, Arkansas, to assess its effectiveness in combating USS and achieving set restoration goals, and to gain insights for future restoration projects. Restoration goals included decreasing erosion and sedimentation, increasing pool …

Haaland V. Brackeen: The Indian Child Welfare Act, States' Rights, And The Survival Of America's First Peoples And Nations, Andrew B. Reid

Denver Law Review

At the end of its 2023 term, the United States Supreme Court issued a long-awaited decision on the Indian Child Welfare Act, Haaland v. Brackeen. The Court was presented with the direct conflict between three well-established bodies of constitutional law: (1) the right of individuals against racial discrimination, (2) the rights reserved by the states under Tenth Amendment federalism, and (3) federal supremacy over the states in matters concerning Native peoples and nations. These conflicts risk the survival of Native families, communities, and culture as well as the collective rights of Native peoples to their survival as inherently sovereign nations …

Genetic And Environmental Drivers Of Migratory Behavior In Western Burrowing Owls And Implications For Conservation And Management, Kelly Barr, Christen M. Bossu, Rachael A. Bay, Eric C. Anderson, Jim Belthoff, Lynne A. Trulio, Debra Chromczak, Colleen L. Wisinski, Thomas B. Smith, Kristen C. Ruegg

Faculty Research, Scholarly, and Creative Activity

Migration is driven by a combination of environmental and genetic factors, but many questions remain about those drivers. Potential interactions between genetic and environmental variants associated with different migratory phenotypes are rarely the focus of study. We pair low coverage whole genome resequencing with a de novo genome assembly to examine population structure, inbreeding, and the environmental factors associated with genetic differentiation between migratory and resident breeding phenotypes in a species of conservation concern, the western burrowing owl (Athene cunicularia hypugaea). Our analyses reveal a dichotomy in gene flow depending on whether the population is resident or migratory, with the …

Impacts Of Marine Heatwaves On Top Predator Distributions Are Variable But Predictable, Heather Welch, Matthew S. Savoca, Stephanie Brodie, Michael G. Jacox, Barbara A. Muhling, Thomas A. Clay, Megan A. Cimino, Scott R. Benson, Barbara A. Block, Melinda G. Conners, Daniel P. Costa, Fredrick D. Jordan, Andrew W. Leising, Chloe S. Mikles, Daniel M. Palacios, Scott A. Shaffer, Lesley H. Thorne, Jordan T. Watson, Rachel R. Holser

Faculty Research, Scholarly, and Creative Activity

Marine heatwaves cause widespread environmental, biological, and socio-economic impacts, placing them at the forefront of 21st-century management challenges. However, heatwaves vary in intensity and evolution, and a paucity of information on how this variability impacts marine species limits our ability to proactively manage for these extreme events. Here, we model the effects of four recent heatwaves (2014, 2015, 2019, 2020) in the Northeastern Pacific on the distributions of 14 top predator species of ecological, cultural, and commercial importance. Predicted responses were highly variable across species and heatwaves, ranging from near total loss of habitat to a two-fold increase. Heatwaves rapidly …

Hyperbolic Matrix Factorization Improves Prediction Of Drug-Target Associations, Aleksandar Poleksic

Faculty Publications

Past research in computational systems biology has focused more on the development and applications of advanced statistical and numerical optimization techniques and much less on understanding the geometry of the biological space. By representing biological entities as points in a low dimensional Euclidean space, state-of-the-art methods for drug-target interaction (DTI) prediction implicitly assume the flat geometry of the biological space. In contrast, recent theoretical studies suggest that biological systems exhibit tree-like topology with a high degree of clustering. As a consequence, embedding a biological system in a flat space leads to distortion of distances between biological objects. Here, we present …

An Integrated Theoretical Examination Of General Strain And Identity Theory To Describe Lesbian, Gay, And Bisexual (Lgb) Youth Drug Use, Ciarra I. Hastings

All Dissertations

In recent years, the United States has experienced an increase in LGBT+ youth perpetrating drugs, sex, and violent offenses. According to identity theory, individuals maintain three main identities that if incongruent can create friction which could lead to crime. The friction may involve the LGBT+ identity and other contributing factors such as demographics age, race, religion, level of education, adverse childhood experiences, stigmatization, discrimination, mental illness, and identity measures (masculine versus feminine identities and sexual minority identity).

This study examined how the LGBT+ identity may create a strain with an individual’s three main identities, personal, group, and societal, and how …

Crispr-Cas Enabled Dna Nanotechnology For Advanced Pathogen Detection, Mahera J. Kachwala

Legacy Theses & Dissertations (2009 - 2024)

The ever-growing list of carcinogens, toxicants, pathogens, and other disease-causing agents necessitates the development of new and improved mechanisms of disease detection. A better understanding of events leading up to the diseased state and early diagnosis is imperative for the timely management and targeted treatment of diseases affecting the biological world. Recent achievements in DNA nanotechnology have led to the prominence of DNA-based technologies for multiplexed biological sensing, high-throughput analysis, and improved diagnostics. Typical methods of disease detection employ complex multi-step procedures and advanced equipment, which significantly reduces their accessibility while elevating their cost. DNA functionalized sensing systems that examine …

Applications Of Diels-Alder Cycloadditions And Transition Metals As Catalysts To Recent Total Syntheses, Alexander H.C. Evans

Legacy Theses & Dissertations (2009 - 2024)

This thesis examines the recent advances in the applications of Diels-Alder cycloaddition reaction and Suzuki-Miyaura coupling to total syntheses of antibiotic and anti-cancer drugs. Attention is also given to intramolecular Diels-Alder cycloadditions and the use of Kinetic vs. Thermodynamic conditions. The results of the Diels-Alder cycloadditions that are discussed oftentimes result in high stereospecificity, regioselectivity, and stereoselectivity. The applications of Suzuki-Miyaura coupling and transition metal catalysts to total syntheses problems are also discussed along a similar narrative. Attention is given specifically to the use of several different gold catalysts as well as Grubb’s Catalyst. The use of the Diels-Alder cycloaddition …

The Effects Of Aggregation Of Tetrafluoro(Trifluoromethyl-Λ6-Sulfanyl) Ethanes On The Secondary Structure Stabilization Of Melittin: A Molecular Dynamics Simulation Study, Samadrita Biswas

Legacy Theses & Dissertations (2009 - 2024)

Introduction of novel tetrafluoro(trifluoromethyl-λ6-sulfanyl) (CF3SF4) functional group has garnered substantial interest because of its increased hydrophobicity. This super fluorinated group attributed to increased lipophilicity, decreased heat of vaporization, and lowered dielectric constants. The highly electronegative nature of this group can profoundly influence the reactivity of compounds containing the CF3SF4 moiety. The hypervalency associated with this new group presents an exciting platform to explore the fundamental understanding of molecular interactions, reactivity patterns, and electronic behaviors. This dissertation investigates the molecular properties and behaviors of tetrafluoro(trifluoromethyl-λ6-sulfanyl) ethanes (CF3SF4-ethanes), with a specific emphasis on 2-tetrafluoro(trifluoromethyl)-λ6-sulfanylethan-1-ol (CF3SF4-ethanol) and 2-tetrafluoro(trifluoromethyl)-λ6-sulfanylethanamine (CF3SF4-ethanamine). Utilizing ab initio calculations …

Intergenerational Transmission Of Gendered Cultural Traditions And Environmental Stewardship Values Among Adirondack Hunters, Kaitlin S. Long

Legacy Theses & Dissertations (2009 - 2024)

Hunting is not simply a sport, but rather a culture that connects practitioners to each other, to the natural environment, and to those who have come before them and will continue the tradition long after they are gone. As a culture intertwined with the environment in which practices and traditions take place, hunting can act as a mechanism for both environmental conservation efforts and the performance of a particular type of ethics. This dissertation explores how hunting values and traditions are transmitted to new, more diverse generations of hunters, how hunters forge and maintain connections through hunting, and how hunting …

Identification Of Genes Conferring Resistance To 2-Amino-3-Methylimidazo [4,5-F] Quinoline Genotoxicity In Budding Yeast Using High-Throughput And Targeted Approaches, Michael J. Dolan

Legacy Theses & Dissertations (2009 - 2024)

Heterocyclic aromatic amines (HAAs) are potent carcinogenic agents found in charred read meat and cigarette smoke. We hypothesize that HAAs may contribute to red meat being a risk factor for colorectal cancer (CRC). At present, few eukaryotic genes conferring resistance to HAAs have been identified. In this research, the genome of Saccharomyces cerevisiae (budding yeast) was profiled using next-generation sequencing to identify genes conferring resistance to one such HAA, 2-amino-3-methylimidazo[4,5-f] quinoline (IQ).CYP1A2 and NAT2 activate IQ to become a mutagenic nitrenium compound. Deletion libraries expressing human CYP1A2 and NAT2 or no human genes were exposed to either 400 or 800 …

Overexpression Of Plasminogen Activator Inhibitor-1 (Pai-1) In Human Kidney Cells, Khadija Rafiqi

Legacy Theses & Dissertations (2009 - 2024)

The research focuses on two key objectives: Mapping renal epithelial cells' response to PAI-1 overexpression and investigating the potential activation of signaling kinases in this context. Utilizing Proteome profiler kits and western blot analysis, the aim is to unravel the underlying mechanisms and signaling pathways involved. By exploring these complexities, the thesis aims to advance our understanding of kidney inflammation and its potential contribution to targeted therapeutic approaches in the future.

Associations Between Maternal Alcohol Consumption During Pregnancy And Selected Musculoskeletal Birth Defects Among Offspring In The National Birth Defects Prevention Study, Sarah Fisher

Legacy Theses & Dissertations (2009 - 2024)

Maternal alcohol consumption during pregnancy is known to be associated with poor pregnancy outcomes, including fetal alcohol spectrum disorders. However, evidence for associations between alcohol consumption during pregnancy and some major structural birth defects among offspring is conflicting or inconclusive. This dissertation used data from the National Birth Defects Prevention Study (NBDPS), a multi-site, population-based case-control study, to examine associations between maternal alcohol consumption and risk of three major musculoskeletal birth defects: gastroschisis, omphalocele, and craniosynostosis. Our analyses built upon previous analyses of these associations using NBDPS data, including larger sample sizes and more robust analytic methods to explore issues …

Bookending The Germ Cell To Maternal Transition: Dynamics Of Gene Regulation In Drosophila Oogenesis, Kahini Sarkar

Legacy Theses & Dissertations (2009 - 2024)

Throughout the process of oogenesis, spanning from flies to humans, germ cells undergo a remarkable transformation, transitioning from a mitotic to a meiotic cell cycle. This intricate journey involves highly specialized cellular processes and culminates in the establishment of a maternal contribution, which plays a crucial role in promoting proper embryogenesis. Despite the significance of these transitions, their regulatory mechanisms have remained largely elusive, until now.

Exploring The Molecular Landscape Of Hepatitis C Virus: Insights Into Viral Replication And Host Interactions, Deniece Brown

Legacy Theses & Dissertations (2009 - 2024)

Hepatitis C Virus (HCV) remains a pressing global health concern, affecting millions of individuals worldwide. Gaining a thorough understanding of the virus's life cycle is pivotal for devising effective treatment strategies. This thesis takes a deep dive into the various stages of HCV's lifecycle, encompassing viral entry, replication, assembly, and release. By unraveling the intricacies of these processes, researchers can pinpoint potential targets for therapeutic interventions.

The Effect Of Autonomic Nervous System Functioning And Childhood Maltreatment On Empathy In Early Adulthood, Edward Charles Merritt

Legacy Theses & Dissertations (2009 - 2024)

Childhood maltreatment has a well-established link to both physical and psychological detriments later in life. Specifically, maltreatment has been found to be associated with changes in physiological functioning and increased aggressive behavior. Despite the well understood link with aggressive behavior, few studies have focused on the effects childhood maltreatment has on empathetic and prosocial behavior. Experienced adversity is theorized to increase one’s tendencies to adopt perspective and to feel a sense of responsibility for another’s welfare (Lim & DeSento, 2016). This study aims to examine how baseline autonomic functioning of the sympathetic and parasympathetic nervous system moderate the relationship between …

Toward A Seed Commons: Practicing Commons For Future Economies, Caitlin Corleen Denny

Legacy Theses & Dissertations (2009 - 2024)

ABSTRACT In this thesis, commons theory is utilized to critically assess the impact of the expanding consolidation of the global seed industry on the seed's status as a common resource. Various understandings of the commons are considered and contradictions and recent insights into the significance of relational dynamics in commons governance are acknowledged. I argue that our daily interactions are instrumental in reconstructing the commons and act as transitional ways of relating that can guide us toward future economies. I use instances of cooperation in the Capital Region, as well as existing seed commons at both local and global scales, …

Induction Of Protective Immunity In The Respiratory Tract With Ricin Toxin Immune Complexes, Lindsey Elizabeth Tolman

Legacy Theses & Dissertations (2009 - 2024)

Ricin toxin (RT) is generated in the seeds of Ricinus communis. The highly potent toxin is comprised of two subunits, RTA and RTB. RT enters cells using RTB before RTA separates itself and inactivates the ribosome, inducing cell stress, inflammation, and eventual death. RT is particularly damaging in the respiratory tract, where intoxication induces an inflammatory cytokine storm.Though there are currently no therapeutics for RT intoxication, our group has generated and characterized a wide variety of monoclonal antibodies (mAbs) against RT. Among the top candidates in our collection are the IgGs PB10 and SylH3. Previous studies have demonstrated their exceptional …

Non-Invasive Focused Ultrasound Treatment To Improve Depressive-Like Behavior In A Hemi-Parkinsonian Rat Model, Huda Rehman

ALL - Honors Theses

Parkinson’s disease (PD) is a neurodegenerative disorder in which there is a depletion of dopaminergic neurons in the substantia nigra pars compacta (SNc). Symptoms include those that are motor, such as tremors and rigidity, along with symptoms that are nonmotor, such as depression. Depression in Parkinson’s disease is seen in up to 50% of PD patients, and is often treated with traditional antidepressants, with varying levels of efficacy. In this research project, focused ultrasound was used as a non-pharmacological and non-invasive treatment to improve depressive-like behavior in a hemi-Parkinsonian rat model. To induce a hemi-Parkinsonian phenotype in rats, stereotaxic surgeries …

Camouflaging And Identity Development Among Autistic Female And Gender Diverse Youth: A Qualitative Exploration, Krista Nicole Drapalik

Legacy Theses & Dissertations (2009 - 2024)

Adolescence is a vulnerable developmental period for autistic female and gender diverse youth. Many autistic youths use camouflaging to combat social challenges, perceived differences, and stigmatization. Although adolescence is an integral time for identity development, integration of these topics remains understudied among autistic female and gender diverse youth. The present study seeks to qualitatively explore first-person, youth-perspectives on the topics of camouflaging and identity formation. Ten autistic female and gender diverse youth aged 11 to 16 years (M = 13.1, SD = 1.52) and their caregivers were enrolled in the present study. Youths completed semi-structured interviews and focus group discussions. …

The Association Between Maternal Exposure To Traffic-Related Air Pollution And Neonatal Death, Low Birthweight, And Orofacial Clefts Among Newborns In New York State, Excluding New York City (1999-2019), Douglas Done

Legacy Theses & Dissertations (2009 - 2024)

The following dissertation describes three case-control studies designed to investigate the association between maternal exposure to traffic-related air pollution (TRAP) and the following three outcomes in newborns: 1) neonatal death; 2) low birthweight; and 3) orofacial clefts. Exposure to TRAP will be assessed using distance-weighted traffic density (DWTD), measured in vehicles per day (VPD) that accounts for all roadways within 228.6-meter (750 ft) of the mother’s residence at the time of birth and the intensity of their average annual daily traffic (AADT) based on roadway and traffic data collected by the NYS Department of Transportation (NYS DOT) from 1995 to …

Adverse Family Experiences And Ethnicity As Risk And Resiliency Factors In The Link Between Psychological Distress And Perception Of Academic Stress In Undergraduate Students, Teresa Mejia

Legacy Theses & Dissertations (2009 - 2024)

Mental health problems have been associated with lower academic performance amongundergraduate students. In addition to individual well-being, environmental and cultural factors may contribute to greater academic stress. Specifically, early adverse family experiences (e.g., abuse, neglect, and family conflict) can have deleterious impacts on an individual’s emotional adjustment and perception of academic stress. However, the influence of ethnicity on the link between early family adversity and later academic stress has been largely understudied. Objective: This study examined whether adverse family experiences and ethnicity moderate the link between psychological distress and academic stress. Methods: Participants (N = 284, 38.4% male, 59.5% female, …

El Leñador, December 2023, El Leñador Staff

El Leñador Newspaper

El Leñador is an English and Spanish newspaper produced by Humboldt State University students. Our staff cover and provide news to Latinx and other diverse communities on campus and in Humboldt County. We are committed to providing relevant news and expanding the representations and stories told about people of color and other marginalized groups. Our work helps create more social, political and cultural diversity in local media.

El Leñador es un periodico en español y inglés producido por estudiantes de la Universidad Estatal de Humboldt. Nuestro personal cubre y provee noticias a la comunidad Latinx y otras comunidades diversas en …

Postpartum Visitation Policies, Jenna B. Holderman, Morgan E. Matthews

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: Continual support for the birthing person during labor improves delivery outcomes and overall childbirth experiences. How many support people are present and their relation to the birthing person varies based on individual preference, family dynamics, and sociocultural expectations. During the Covid-19 pandemic, many hospitals implemented a one-visitor policy for deliveries. With these new guidelines in place, the length of hospital stays significantly decreased, and there were a variety of opinions towards these restrictions.

Purpose: The purpose of this study was to explore birthing persons’ overall sentiment towards visitors in the immediate postpartum period.

Methods: The current study analyzed …

The Dictator Novel In Ya Latinx Fantasy, Catherine Gallegos

English (MA) Theses

The Dictator Novel in YA Latinx Fantasy explores the power of the dictator novel in Latinx literature, specifically within the young adult fantasy genre. Drawing upon the work of Jennifer Harford-Vargas to examine the relationship between the forms of power and the power of the narrative form and how this creates ways to defy and rebel against repressive authoritarian figures. The young adult Latinx fantasy novel calls for a challenge to the authoritarian presence that occupies these imagined worlds that reach beyond the cycle of oppression and injustices that have silenced generation after generation. These YA Latinx fantasy novels use …

Design Of Human Serum Albumin And Adenovirus Conjugation Via Catcher/Tag Molecular Glue, Peijie Zhao

McKelvey School of Engineering Graduate Student Theses & Dissertations

Adenovirus (Ad) has been the ideal cargo delivery mechanism, and its moderate immunological response makes it ideal for in vivo gene therapies since its discovery in 1953. However, the robust immunogenicity of the Ad capsid and low vaccine absorption via mucous membranes and epithelium put a limit on the process of developing intranasal vaccines. Efforts are being made to enhance the effectiveness of Ad vectors and numerous studies have demonstrated the remarkable capacity of human serum albumin (HSA) to extend plasma half-life and facilitate targeted intranasal delivery. In this study, we devised an innovative method for employing the Catcher/Tag molecular …