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Dysbiosis In Parkinson's Disease: A Meta-Analysis Of Gut Microbiota And Its Role In Gastrointestinal Dysfunction And Disease Progression, Ayan M. Siddiqui Mr. Jan 2024

Dysbiosis In Parkinson's Disease: A Meta-Analysis Of Gut Microbiota And Its Role In Gastrointestinal Dysfunction And Disease Progression, Ayan M. Siddiqui Mr.

Honors Undergraduate Theses

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor symptoms, including gastrointestinal (GI) dysfunction. Symptoms such as constipation, bloating, and nausea often show early signs before the onset of motor symptoms. Recent research has suggested an essential role of the human gut microbiome and gut dysbiosis, an imbalance in gut microbiota composition, in the pathogenesis of PD. This thesis aims to assess the potential relationship between gut dysbiosis and PD by conducting a meta-analysis, focusing on differences in gut microbiota between PD patients and healthy controls and evaluating their implications for GI dysfunction and PD progression. The …


Sex Education Experiences Of Lgbtq+ College Students In Florida, Uma Sriram Jan 2024

Sex Education Experiences Of Lgbtq+ College Students In Florida, Uma Sriram

Honors Undergraduate Theses

Existing research has identified negative impacts of state-level policies on sexual and gender minorities, yet minimal research has assessed the impact of recent anti-LGBTQ+ laws in Florida. This study explored the sex education experiences of LGBTQ+ college students who attended public middle and high schools in Florida and their attitudes towards the “Don’t Say Gay” Law, which was passed in 2022 and has since prevented the inclusion of diverse sexual and gender identities within K-12 school environments. Data consisted of 11 in-depth, qualitative interviews with undergraduate LGBTQ+ students attending Florida public universities. Thematic analysis of the interview data was conducted, …


Detection Of Micrornas In Blood Samples Using Biosensors For The Detection Of Early-Stage Lung Cancer, Nicholas Bruno Jan 2024

Detection Of Micrornas In Blood Samples Using Biosensors For The Detection Of Early-Stage Lung Cancer, Nicholas Bruno

Honors Undergraduate Theses

Lung cancer kills more people in the U.S. a year than any other cancer. This is largely because patients often remain asymptomatic until stage 3, by which time the tumor is usually highly malignant. High radiation-producing screenings are the current method of lung tumor detection. These typically involve machinery for tumor visualization, such as computed tomography (CT) scans, positron emission tomography (PET scan), magnetic resonance imaging (MRI), and X-rays. Not only does radiation exposure from this equipment pose a risk to the patient, but any tumors detected by these scanning techniques are likely to be locally advanced. This suggests that …


The Comparative Efficacy Of Ketamine And Esketamine In Treating Anhedonia And Suicidal Ideation: A Meta-Analysis, Yanyi Wu Jan 2024

The Comparative Efficacy Of Ketamine And Esketamine In Treating Anhedonia And Suicidal Ideation: A Meta-Analysis, Yanyi Wu

Honors Undergraduate Theses

This meta-analysis examines the efficacy and effectiveness of racemic ketamine (RS-ketamine) and esketamine in reducing depressive symptoms such as suicidal ideation and anhedonia in patients suffering from treatment-resistant depression and bipolar disorder. This review comprehensively looks at six studies: three clinical studies focusing on suicidal ideation and three looking at anhedonia. Across the studies, RS-ketamine and esketamine were associated with a higher resolution of suicidal ideation, risk, and anhedonia. Significant improvements were noted in the suicidal desire and ideation subscale of the Beck Scale for Suicidal Ideation. The pooled effect size for suicidal ideation (d = 0.533) and pooled …


Does Attention Control Mediate The Negative Effects Online Usage Exerts On College Students' Gpa, Carolina Rodriguez Jan 2024

Does Attention Control Mediate The Negative Effects Online Usage Exerts On College Students' Gpa, Carolina Rodriguez

Honors Undergraduate Theses

Online media, especially social media, is a continuously growing area of research which has raised questions about its impacts on academic outcomes. Many previous studies have established a negative relation between social media use and academic performance; however, the mechanism behind this finding is still unknown. The present study investigated whether level of attention control mediates the relation between an individual’s propensity for online usage and grade point average (GPA). Undergraduate students at the University of Central Florida (N=226) were recruited for this study, and their levels of online vigilance and attention control were measured. College GPA was self-reported by …


Effect Of An Intervention Bundle On Thirst Intensity Among Intensive Care Unit Patients, Marwa Abdo, Manal Sayed Ismail, Nayera Mohamed Tantaewy Jan 2024

Effect Of An Intervention Bundle On Thirst Intensity Among Intensive Care Unit Patients, Marwa Abdo, Manal Sayed Ismail, Nayera Mohamed Tantaewy

Nursing

Background: Dry mouth and thirst are commonly associated with a strong desire to drink fluid. Despite this, thirst is often overlooked in the intensive care unit (ICU). Patients in the intensive care unit (ICU) experience various causes of distress. Aim: This study aimed to assess the effect of an intervention bundle on thirst intensity among ICU patients. Methods: A quasi-experimental research design was used with a purposive sample of 100 ICU patients were selected and randomly divided into two groups: the thirst bundle group comprised of 50 ICU patients who received thirst bundle intervention with lip moisturizer, peppermint water mouthwash, …


Synthesizing And Using Iron Oxide Nanoparticles As Nanocomposite In Cotton Fabrics Nanofinishing, Hoda Sharouf, Ziad Saffour Jan 2024

Synthesizing And Using Iron Oxide Nanoparticles As Nanocomposite In Cotton Fabrics Nanofinishing, Hoda Sharouf, Ziad Saffour

Baghdad Science Journal

Metal oxide nanoparticles, including iron oxide, are highly considered as one of the most important species of nanomaterials in a varied range of applications due to their optical, magnetic, and electrical properties. Iron oxides are common compounds, extensive in nature, and easily synthesized in the laboratory. In this paper, iron oxide nanoparticles were prepared by co-precipitation of (Fe+2) and (Fe+3) ions, using iron (II and III) sulfate as precursor material and NH4OH solution as solvent at 90°C. After the synthesis of iron oxide particles, it was characterized using X-ray diffraction (XRD), infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). These …


Preparation And Characterization Of Silver Nanoparticles And Its Medical Application Against Pathogenic Bacteria, Azhin Zainel Abbas, Rosure Borhanalden Abdulrahman, Thikra A. Mustafa Jan 2024

Preparation And Characterization Of Silver Nanoparticles And Its Medical Application Against Pathogenic Bacteria, Azhin Zainel Abbas, Rosure Borhanalden Abdulrahman, Thikra A. Mustafa

Baghdad Science Journal

The fabrication of Solid and Hollow silver nanoparticles (Ag NPs) has been achieved and their characterization was performed using transmission electron microscopy (TEM), zeta potential, UV–VIS spectroscopy, and X-ray diffraction (XRD). A TEM image revealed a quasispherical form for both Solid and Hollow Ag NPs. The measurement of surface charge revealed that although Hollow Ag NPs have a zeta potential of -43 mV, Solid Ag NPs have a zeta potential of -33 mV. According to UV-VIS spectroscopy measurement Solid and Hollow Ag NPs both showed absorption peaks at wavelengths of 436 nm and 412 nm, respectively. XRD pattern demonstrates that …


Bi-Distance Approach To Determine The Topological Invariants Of Silicon Carbide, Abid Mahboob, Muhammad Waheed Rasheed, Jalal Hatem Hussein Bayati, Iqra Hanif, Sajid Mahboob Alam Jan 2024

Bi-Distance Approach To Determine The Topological Invariants Of Silicon Carbide, Abid Mahboob, Muhammad Waheed Rasheed, Jalal Hatem Hussein Bayati, Iqra Hanif, Sajid Mahboob Alam

Baghdad Science Journal

The use of silicon carbide is increasing significantly in the fields of research and technology. Topological indices enable data gathering on algebraic graphs and provide a mathematical framework for analyzing the chemical structural characteristics. In this paper, well-known degree-based topological indices are used to analyze the chemical structures of silicon carbides. To evaluate the features of various chemical or non-chemical networks, a variety of topological indices are defined. In this paper, a new concept related to the degree of the graph called "bi-distance" is introduced, which is used to calculate all the additive as well as multiplicative degree-based indices for …


Genetic Diversity Of Trypanosomes Infesting Cattle From Savannah District In North Of Côte D’Ivoire Using Conserved Genomic Signatures: Rrna, Its1 And Ggapdh, Jean-Yves Ekra, Eliakunda Michael Mafie, Edouard K. N’Goran, Dramane Kaba, Biégo Guillaume Gragnon, Jagan Srinivasan Jan 2024

Genetic Diversity Of Trypanosomes Infesting Cattle From Savannah District In North Of Côte D’Ivoire Using Conserved Genomic Signatures: Rrna, Its1 And Ggapdh, Jean-Yves Ekra, Eliakunda Michael Mafie, Edouard K. N’Goran, Dramane Kaba, Biégo Guillaume Gragnon, Jagan Srinivasan

All Rsif Scholars' Publications

The potential danger to livestock from African animal trypanosomiasis is well known. However, the trypanosome species circulating in cattle and their genetics are poorly understood. After different alignments according to three regions (ITS1, gGAPDH and rRNA gene) of the trypanosome genome, phylogenetic analyses were used to show the genetic diversity of the different species that were circulating in the cattle in three regions (Bagoue, Poro and Tchologo) of Côte d’Ivoire. These analyses were performed by alignment of ITS1; by alignment of partial 18S, ITS1, 5.8S, ITS2 and partial 28S rRNA genes; and by alignment of gGAPDH gene with sequences of …


Empowering Communities Through Education Creating The School Of Green, Kyle Martin Jan 2024

Empowering Communities Through Education Creating The School Of Green, Kyle Martin

Senior Honors Theses and Projects

The School of Green initiative aims to foster environmental stewardship through community-driven STEM education programs. This paper evaluates the initiative’s impact, critiques its planning, and strategizes for future success. It discusses the evolution of the School of Green Series, its community impact, and future directions. The paper also provides a contextual framework reflective analysis and outlines personal motivations and aspirations. Through meticulous documentation and archival research methods, this project aims to detail the significance of the School of Green Series in promoting environmental education and inclusivity. The comprehensive event report will not only analyze successes and areas for improvement but …


Effect Of External Electromagnetic Stimulation On Microtubule Polymerization, Florian Alushi Jan 2024

Effect Of External Electromagnetic Stimulation On Microtubule Polymerization, Florian Alushi

Honors Undergraduate Theses

Intracellular processes are influenced by mass transport at different spatial and temporal scales, facilitated by diffusion and stochastic encounters between cellular components. While traditionally explained by short-range "lock and key" interactions, some processes involve rapidly fluctuating charges generating electromagnetic (EM) fields, allowing long-range biomolecular interactions. This challenges the conventional view that efficient biochemical reactions depend solely on random encounters and short-range interactions, suggesting EM fields play a crucial role in cellular dynamics. Microtubules (MTs) are essential components of the cell cytoskeleton, responsible for intracellular transport, cell migration, cell division, etc. Beyond their mechanical role, MTs have unique electromagnetic properties due …


A Gis Tool For Optimal Forage Species Selection, David B. Hannaway, Christopher Daly, Michael D. Halbleib, Linda Brewer, Sophie Baur, Chelsea Clark, Emilie Krecklow, Scott Bassett Jan 2024

A Gis Tool For Optimal Forage Species Selection, David B. Hannaway, Christopher Daly, Michael D. Halbleib, Linda Brewer, Sophie Baur, Chelsea Clark, Emilie Krecklow, Scott Bassett

IGC Proceedings (1977-2023)

To determine appropriate forage species for US ecoregions, geographic information technologies (GIS) are being used to create climatic and soil factor maps. Excel spreadsheets and RStudio are used to create response functions of forage species to minimum and maximum temperature, annual precipitation, soil pH, soil salinity, and salinity. National forage data and expert opinion will evaluate quantitative tolerances, seasonal yield profiles, and pollinator suitability. These maps and agronomic and livestock use information will be shared with forage specialists and farmers to provide alternatives for improved perenniality, increased diversity, and system circularity. Future work will include development and evaluation of climate …


Justice As Fairness Or As Inclusion: Putting Rawls In Conversation With The Bans On Transgender Athletes, Nicole Player Jan 2024

Justice As Fairness Or As Inclusion: Putting Rawls In Conversation With The Bans On Transgender Athletes, Nicole Player

Pomona Senior Theses

The last decade has seen a flurry of anti-transgender bills introduced and passed in the United States, and the topic that has likely been the most hotly debated regards the dozens of state bans on transgender athletes. While most discussions of these bans go straight to a debate about physiology, this thesis centers instead on a question of justice. In the debate of whether to allow a transgender girl to compete in girls’ sports, is it more “just” to prioritize fairness in women’s sport, as these bans do, or is it more just to prioritize inclusion? This thesis, in finding …


Liposomal Nanoparticle Mediated Gene Modulation For The Treatment Of Melanoma In The Murine Model, Bill Xu Tang Bsa, Poonam Yadav Phd, Rahul Anil Sheth Md, Fsir Jan 2024

Liposomal Nanoparticle Mediated Gene Modulation For The Treatment Of Melanoma In The Murine Model, Bill Xu Tang Bsa, Poonam Yadav Phd, Rahul Anil Sheth Md, Fsir

Students Summer in Oncology at Anderson Research (SOAR) 2024

This study evaluated the efficacy of liposomal nanoparticles (LNPs) in delivering Wnt/β-catenin-inhibiting mIR-124 plasmids to melanomas. In vitro, LNPs with mIR-124 were applied to B16N2 melanoma cells. In vivo, LNPs were injected into B16N2 tumors in mice. Delivery success was confirmed via flow cytometry and RT-PCR, assessing GFP expression, tumor transition markers, and Wnt/β-catenin signaling. Overall, the findings suggested that LNP-mediated delivery of Wnt/β-catenin inhibitors holds promise as a therapeutic strategy for melanoma, with trends indicating a reversal of epithelial-mesenchymal transition (EMT) and slowed melanoma progression.


Lis Journals' Lack Of Participation In Wikidata Item Creation, Eric Willey, Susan Radovsky Jan 2024

Lis Journals' Lack Of Participation In Wikidata Item Creation, Eric Willey, Susan Radovsky

Faculty and Staff Publications – Milner Library

There are many items in Wikidata representing scholarly articles. However, these items have been created mostly by volunteer Wikidata editors and not systematically by journal publishers or editors, which can lead to gaps and inconsistencies in the datasets. This article presents findings from a survey investigating practices of library and information studies (LIS) journals in Wikidata item creation. Believing that a significant number of LIS journal editors would be aware of Wikidata and some would be creating Wikidata items for their publications, the authors sent a survey asking 138 English-language LIS journal editors if they created Wikidata items for materials …


Comparative Anatomy Of Mouse, Zebrafish, And Trout, Adnan Alyan Jan 2024

Comparative Anatomy Of Mouse, Zebrafish, And Trout, Adnan Alyan

IdeaFest 2024

No abstract provided.


Orchid Micropropagation And The Potential For Conservation, Rebecca Bendzick, Heidi Rutschow, Valori Mraz Jan 2024

Orchid Micropropagation And The Potential For Conservation, Rebecca Bendzick, Heidi Rutschow, Valori Mraz

IdeaFest 2024

No abstract provided.


Role Of Recreational Trailways And Cover Objects In Relation To Terrestrial Salamanders, Anthony Gomez Jan 2024

Role Of Recreational Trailways And Cover Objects In Relation To Terrestrial Salamanders, Anthony Gomez

IdeaFest 2024

No abstract provided.


Investigating How Lgl1 Loss Affects The Murine Brain Cytoarchitecture, Madison Gutierrez, Ashley King Jan 2024

Investigating How Lgl1 Loss Affects The Murine Brain Cytoarchitecture, Madison Gutierrez, Ashley King

IdeaFest 2024

No abstract provided.


Benefits Of Birth By Water Immersion, Kylie Dennhardt Jan 2024

Benefits Of Birth By Water Immersion, Kylie Dennhardt

IdeaFest 2024

No abstract provided.


Analysis Of Acidity, Co2 And Oxygen Concentration During Summer Upwelling Conditions In Humboldt Bay, Northern California, Lindsey Fischer Jan 2024

Analysis Of Acidity, Co2 And Oxygen Concentration During Summer Upwelling Conditions In Humboldt Bay, Northern California, Lindsey Fischer

IdeaFest 2024

No abstract provided.


Multifaceted: Sem Analysis Of Entolomatoid Basidiospores, Casey Ledford, Frank Cappuccio Jan 2024

Multifaceted: Sem Analysis Of Entolomatoid Basidiospores, Casey Ledford, Frank Cappuccio

IdeaFest 2024

No abstract provided.


Agent-Based Modeling Of Microglia Behavior In The Context Of Alzheimer's Disease, Emmanuel Mezzulo, Cheyenne Ty, Amanda Case, Abigail Penland, Kamila Larripa Jan 2024

Agent-Based Modeling Of Microglia Behavior In The Context Of Alzheimer's Disease, Emmanuel Mezzulo, Cheyenne Ty, Amanda Case, Abigail Penland, Kamila Larripa

IdeaFest 2024

No abstract provided.


The Therapeutic Potential Of Exercise For Substance Use Disorder: Targeting Stress Resilience, Neuroplasticity, And Reward Pathways, Lillian Maddock Jan 2024

The Therapeutic Potential Of Exercise For Substance Use Disorder: Targeting Stress Resilience, Neuroplasticity, And Reward Pathways, Lillian Maddock

IdeaFest 2024

No abstract provided.


Pacific Purple Sea Urchin Movement Trends, Holly Elbert Jan 2024

Pacific Purple Sea Urchin Movement Trends, Holly Elbert

IdeaFest 2024

No abstract provided.


Influence Of Running Shoes On Running Economy, Injury Performance, And Biomechanical Efficiency, Sawyer Stoddard Jan 2024

Influence Of Running Shoes On Running Economy, Injury Performance, And Biomechanical Efficiency, Sawyer Stoddard

IdeaFest 2024

No abstract provided.


Scanning Electron Microscope Imaging Of Nitropentaamminecobalt(Iii) Chloride ([Co(Nh3)5no2]Cl2) Crystal Structure, David Morales Jan 2024

Scanning Electron Microscope Imaging Of Nitropentaamminecobalt(Iii) Chloride ([Co(Nh3)5no2]Cl2) Crystal Structure, David Morales

IdeaFest 2024

No abstract provided.


Stylohyoid-Tympanic Articulation In Shrews And Its Possible Implications For Echolocation, Silvia Pavan, Aviva Saadatfar, Jesyka Rosa Jan 2024

Stylohyoid-Tympanic Articulation In Shrews And Its Possible Implications For Echolocation, Silvia Pavan, Aviva Saadatfar, Jesyka Rosa

IdeaFest 2024

No abstract provided.


Habitat Preferences And Distribution Patterns Of Salamanders In The Arcata Community Forest, Tristan Ray Jan 2024

Habitat Preferences And Distribution Patterns Of Salamanders In The Arcata Community Forest, Tristan Ray

IdeaFest 2024

No abstract provided.