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Articles 87841 - 87870 of 818760
Full-Text Articles in Entire DC Network
Development Of A New Green Infrastructure By Using Biochar Amended Topsoil For On-Site Stormwater Runoff Treatment, Ayesha Sadia
Development Of A New Green Infrastructure By Using Biochar Amended Topsoil For On-Site Stormwater Runoff Treatment, Ayesha Sadia
College of Graduate Studies: Theses & Dissertations
This Research Project aimed to design, build, operate and maintain, and monitor a new green infrastructure (GI) using biochar-amended topsoil for on-site stormwater runoff treatment in urban areas. The project involved evaluating the removal efficiencies of pollutants from stormwater runoff such as total suspended solid (TSS), nutrients including nitrogen and phosphorous, heavy metals including lead (Pb), zinc (Zn) and copper (Cu) and oil and grease etc. from the media of biochar amended topsoil. In this Project, a full-scale Field Test Site with a total area of 500 and 1 ft depth was built to on-site treat stormwater runoff from a …
Problems In Chemical Graph Theory Related To The Merrifield-Simmons And Hosoya Topological Indices, William B. O'Reilly
Problems In Chemical Graph Theory Related To The Merrifield-Simmons And Hosoya Topological Indices, William B. O'Reilly
College of Graduate Studies: Theses & Dissertations
In some sense, chemical graph theory applies graph theory to various physical sciences. This interdisciplinary field has significant applications to structure property relationships, as well as mathematical modeling. In particular, we focus on two important indices widely used in chemical graph theory, the Merrifield-Simmons index and Hosoya index. The Merrifield-Simmons index and the Hosoya index are two well-known topological indices used in mathematical chemistry for characterizing specific properties of chemical compounds. Substantial research has been done on the two indices in terms of enumerative problems and extremal questions. In this thesis, we survey known extremal results and consider the generalized …
Characterization Of Carbon Nanotube/Polystyrene Composites Prepared Via Microwave-Induced Polymerization, Hubert Agamasu
Characterization Of Carbon Nanotube/Polystyrene Composites Prepared Via Microwave-Induced Polymerization, Hubert Agamasu
College of Graduate Studies: Theses & Dissertations
Carbon nanotubes (CNTs), with their excellent mechanical properties, are well suited to the production of composites with good strength-to-weight ratio. However, the use of nanotubes as reinforcement is hampered by the lack of interaction between their inert surfaces and matrices. This, coupled with the van der Waal’s interactions between individual nanotubes, leads to agglomeration of CNTs in media. Functionalization is an efficient means to disperse nanotubes as well as increase their reactivity. The irradiation of CNTs with microwaves generates instantaneous, localized heating, being used in this work to trigger the rapid, thermal, free radical polymerization of styrene. Under microwaves, olefin-functionalized …
Nanosecond Pulsed Electric Fields Increase Antibiotic Susceptibility In Methicillin-Resistant Staphylococcus Aureus, Alexandra E. Chittams-Miles, Areej Malik, Erin B. Purcell, Claudia Muratori
Nanosecond Pulsed Electric Fields Increase Antibiotic Susceptibility In Methicillin-Resistant Staphylococcus Aureus, Alexandra E. Chittams-Miles, Areej Malik, Erin B. Purcell, Claudia Muratori
Bioelectrics Publications
Staphylococcus aureus is the leading cause of skin and soft-tissue infections (SSTIs). SSTIs caused by bacteria resistant to antimicrobials, such as methicillin-resistant S. aureus (MRSA), are increasing in incidence and have led to higher rates of hospitalization. In this study, we measured MRSA inactivation by nanosecond pulsed electric fields (nsPEF), a promising new cell ablation technology. Our results show that treatment with 120 pulses of 600 ns duration (28 kV/cm, 1 Hz), caused modest inactivation, indicating cellular damage. We anticipated that the perturbation created by nsPEF could increase antibiotic efficacy if nsPEF were applied as a co-treatment. To test this …
Dihydroethidium-Derived Fluorescence In Electrically Stressed Cells Indicates Intracellular Microenvironment Modifications Independent Of Ros, Esin B. Sözer, Iurii Semenov, P. Thomas Vernier
Dihydroethidium-Derived Fluorescence In Electrically Stressed Cells Indicates Intracellular Microenvironment Modifications Independent Of Ros, Esin B. Sözer, Iurii Semenov, P. Thomas Vernier
Bioelectrics Publications
Intracellular reactive oxygen species (ROS) generation is widely suggested as a trigger for biological consequences of electric field exposures, such as those in electroporation applications. ROS are linked with membrane barrier function degradation, genetic damage, and complex events like immunological cell death. Dihydroethidium (DHE) is commonly used to monitor ROS in cells. DHE is linked to intracellular ROS by a primary oxidation product, Ethidium (Eth+), that shows increased fluorescence upon binding to polynucleotides. We observed changes in DHE-derived fluorescence in Chinese hamster ovary (CHO) cells post 300-ns electric pulse exposures, comparing them to tert-butyl-hydroperoxide (t-BHP) induced oxidative stress. …
Dependent Competing Failure Processes In Reliability Systems, Jewgeni H. Dshalalow, Hend Aljahani, Ryan T. White
Dependent Competing Failure Processes In Reliability Systems, Jewgeni H. Dshalalow, Hend Aljahani, Ryan T. White
Mathematics and System Engineering Faculty Publications
This paper deals with a reliability system hit by three types of shocks ranked as harmless, critical, or extreme, depending on their magnitudes, being below (Formula presented.), between (Formula presented.) and (Formula presented.), and above (Formula presented.), respectively. The system’s failure is caused by a single extreme shock or by a total of N critical shocks. In addition, the system fails under occurrences of M pairs of shocks with lags less than some (Formula presented.) ((Formula presented.) -shocks) in any order. Thus, the system fails when one of the three named cumulative damages occurs first. Thus, it fails due to …
Mouralherwaqh Coastal Wetland Road Crossing Da'luk, Natalie Mendez
Mouralherwaqh Coastal Wetland Road Crossing Da'luk, Natalie Mendez
Cal Poly Humboldt theses and projects
The integration of Indigenous and Western science plays an essential role in Tribally led collaborations for land management. This process of woven sciences is rooted in reciprocal relations and partnerships guided by Tribal Nations. Our cohort was invited by Wiyot Tribal Representatives to investigate a culvert located within the wetlands of Mouralherwaqh— a parcel of land reacquired by the Wiyot Tribe in 2022. This document seeks to share our experience and analysis as part of the Wiyot Tribe’s broader journey in navigating ecocultural restoration projects within Mouralherwaqh. The four community interests we investigated for the wetland crossing included a resized …
Microbes: Key Constituent Of Predator Risk Cues?, Jake R. Vargas
Microbes: Key Constituent Of Predator Risk Cues?, Jake R. Vargas
Cal Poly Humboldt theses and projects
Chemical cues emanating from predators can play a key role in aquatic predator-prey interactions and food webs. Understanding how prey respond to these risk cues is therefore critical for understanding the direct effects of predators on prey populations and their indirect effects on communities. To respond adaptively, prey must accurately assess the risk of predation associated with perceived chemical cues, an oft-documented phenomenon. However, little is known about how cues disperse, persist, and degrade, all of which could limit the adaptive responses of prey. Using laboratory-based observations of a well-studied predator cue-induced antipredator behavior by the marine gastropod Tegula funebralis …
Using Habitat Modeling To Locate New Populations Of Dunn's Salamander (Plethodon Dunni) Near Its Southern Geographic Range Limit, Mary A. Mackey
Using Habitat Modeling To Locate New Populations Of Dunn's Salamander (Plethodon Dunni) Near Its Southern Geographic Range Limit, Mary A. Mackey
Cal Poly Humboldt theses and projects
Habitat suitability models were utilized to direct survey efforts for Plethodon dunni in Northern California. Two models were created, one using traditional statistical methods (GLM or Generalized Linear Modeling) and the other using a machine learning method (MaxEnt or Maximum Entropy modeling). Plots were selected from areas of agreement and disagreement between the models to carry out presence surveys. The MaxEnt model yielded better predictions than the GLM model. The two models had three variables in common (annual temperature range, precipitation of driest month, and precipitation seasonality) and predicted suitable habitat within the known range of P. dunni. The …
Longevity Of Prescribed Fire Effectiveness In Mixed-Evergreen Forests Of The Klamath Mountains, Kaily M. Fineran
Longevity Of Prescribed Fire Effectiveness In Mixed-Evergreen Forests Of The Klamath Mountains, Kaily M. Fineran
Cal Poly Humboldt theses and projects
Prescribed fire is a common management tool used across the western United States to create wildfire-resilient ecosystems and communities. The Klamath Mountains of northern California, USA has experienced numerous, large wildfires in recent years. This is due in part to a combination of highly flammable fuels, uncharacteristic weather events, and high fuel accumulations as a result of fire exclusion and forest management practices. Within the last decade, local land management organizations and the Karuk Tribe have begun re-introducing prescribed fire in low elevation, mixed evergreen forests. While the long-term effects of fuel treatments are not well-known, these efforts provided a …
Characterizing The Habitat Use Of Pacific Coast Feeding Group Gray Whales (Eschrichtius Robustus) And The Spatial And Temporal Variability Of Their Benthic And Planktonic Invertebrate Prey In Northern California, Robyn E. Norman
Cal Poly Humboldt theses and projects
As opportunistic foragers, the Eastern North Pacific population (~20,000) of gray whales (Eschrichtius robustus) feed on diverse benthic and planktonic invertebrates in northern Alaska foraging grounds before they undertake one of the largest yearly migrations of any mammal to breed in Baja California, Mexico. While most of the population travels to the summer foraging grounds in Alaska, a sub-group of whales (~230) called the Pacific Coast Feeding Group (PCFG) summer between British Columbia, Canada, and northern California. The diet of PCFG whales typically includes high-density and/or high-caloric prey items like mysids and diverse species of amphipods, yet a …
Building Detailed And Accurate Whole-Plant Concepts: A Morphometrics-Informed Reconstruction Of A Zosterophyll From The Lower Devonian Of Wyoming, Samar R. El-Abdallah
Building Detailed And Accurate Whole-Plant Concepts: A Morphometrics-Informed Reconstruction Of A Zosterophyll From The Lower Devonian Of Wyoming, Samar R. El-Abdallah
Cal Poly Humboldt theses and projects
The fragmentary state of plant fossils and the modular organization of plants make whole-plant reconstructions of fossil species desirable and feasible. Such reconstructions are key for integrating fossil species in systematic studies. The ca. 410 Ma Beartooth Butte Formation of Wyoming (USA) hosts the only rich Early Devonian plant assemblages in western North America, which fills a major gap in the phytogeography of this interval. I construct a whole-plant concept for a new zosterophyll from the Beartooth Butte Formation based on a detailed morphometric study. More than 600 fragments of the new zosterophyll were observed and 200 of those were …
Neurocinematics And Empathy: How Cognitive Neuroscience Enhances Our Understanding Of Emotional Responses Of Film, Kira Trinity
Neurocinematics And Empathy: How Cognitive Neuroscience Enhances Our Understanding Of Emotional Responses Of Film, Kira Trinity
Cal Poly Humboldt theses and projects
Cinema is a medium that is beloved around the globe since its inception over a century ago. There have been speculations on how it is that cinema works, from editing to emotional processing of the story, but only recently have we begun to explore the inner workings of cinematic impact on the brain. In this paper we will review research on cinematic impact and define cinematic editing, discuss the birth of “neurocinematics”, highlight what we have observed with regards to neuroimaging and empathy when viewing films, and speculate on how our responses to cinema may be driven by the Mirror …
Post-Fire Vegetation And Pyrodiversity Influence Breeding Abundances Of Lewis's Woodpeckers In The Eastern Cascades, Oregon, Brittany Welch
Post-Fire Vegetation And Pyrodiversity Influence Breeding Abundances Of Lewis's Woodpeckers In The Eastern Cascades, Oregon, Brittany Welch
Cal Poly Humboldt theses and projects
Lewis’s woodpeckers (Melanerpes lewis) are described as "burn specialists" due to their preference for breeding in recently burned pine forests in the western US. However, despite increasing fire activity, this species experienced a 48% range-wide decline between 1968 and 2019, which raises questions about their adaptability to altered fire regimes in the region. We partnered with the Oregon Department of Fish & Wildlife to investigate how Lewis’s woodpeckers in the eastern Cascades, Oregon were influenced by post-fire habitat characteristics such as snag size, snag density, and burn severity across five wildfires that varied in fire age, size, and …
The Nature And Extent Of Algal Symbiosis In Three North American Ranids, Zachary T. Vegso
The Nature And Extent Of Algal Symbiosis In Three North American Ranids, Zachary T. Vegso
Cal Poly Humboldt theses and projects
The symbiotic relationship between the chlamydomonad green alga Oophila amblystomatis and embryos of certain amphibian species is often presumed to be mutualistic. However, the existence of a mutualism has only been experimentally tested and established in two closely related ambystomatid salamanders. These experiments showed a positive correlation between intracapsular algal density and embryonic growth, survival, hatching synchrony, and hatchling body size. Oophila has been documented within egg capsules of a growing number of amphibian species, including several frogs in the family Ranidae. However, the nature and extent of this relationship remains unclear. Ranid eggs are better oxygenated than ambystomatid eggs, …
Common Raven Resource Selection, Diet, And Behavior Around A Threatened Shorebird, Janelle Chojnacki
Common Raven Resource Selection, Diet, And Behavior Around A Threatened Shorebird, Janelle Chojnacki
Cal Poly Humboldt theses and projects
Human food subsidies have allowed populations of the common raven (Corvus corax) to expand and increase in density, especially in the western United States, which has amplified predation risk for other native species. Common ravens are well-documented nest predators of the federally threatened Western snowy plover (Anarhynchus nivosus nivosus) in Humboldt County, California; however, little is known about raven movement and foraging behavior in and around snowy plover habitat. Using GPS tracking and behavioral surveys, I examined movement and foraging behavior of beach-going ravens across snowy plover nesting habitat and I explored raven diet through stable isotope …
Using Biological Parameters And Traditional Ecological Knowledge To Study The Status Of Spirinchus Starksi (Night Smelt) In Northern California, Z. Zenobia
Cal Poly Humboldt theses and projects
Night smelt spawns from central California to southeast Alaska, on the shore of sandy beach surf zones at night. This species is a vital part of regional food webs and, in California, is fished commercially primarily in Humboldt and Del Norte counties. It has cultural importance for dietary and subsistence needs to the Tribes across the coast, as well as inland. The objectives of this thesis are as follow: study the status of the population of night smelt in Humboldt and Del Norte counties by (A) comparing the abundance, length, weight, age, sex ratio, and timing of reproduction of the …
Movement-Based Interventions To Support Executive Function And Emotional Regulation In Autism Through The Potential Molecular Induction Of Neuroplasticity: A Systematic Review, Julie Dalmolen
Cal Poly Humboldt theses and projects
Autism Spectrum Disorder is associated with cognitive challenges that can hinder Executive Function. Disruptions in ER tend to create the largest barriers to social interactions with peers and can lead to disengagement from social activities and increased isolation which can impede learning and increase sedentary behaviors. Exercise interventions have been extensively studied in the autism population. While research suggests a variety of movement-based practices are effective in supporting metabolism, motor skills, stereotypical behaviors, and executive function, the impacts on emotional regulation are less clear, as are the types of exercise interventions that have the greatest effects. This systematic review aimed …
The Effectiveness Of A Visual Activity Schedule In Aquatics On Skill Acquisition In Individuals With Autism Spectrum Disorder, Marcus J. Romero
The Effectiveness Of A Visual Activity Schedule In Aquatics On Skill Acquisition In Individuals With Autism Spectrum Disorder, Marcus J. Romero
Cal Poly Humboldt theses and projects
This study investigates the effectiveness of a Visual Activity Schedule (VAS) on the acquisition of aquatic skills (floating, front glide, and breath control) in individuals with autism spectrum disorder (ASD). Due to the heightened risk of drowning among people with ASD, this research aims to determine if a VAS can enhance learning and safety in aquatic environments. The study utilizes a multiple baseline design across skills, involving two male participants aged 16 and 17 years old, both diagnosed with ASD. Baseline assessments were administered and followed by intervention phases where VAS was introduced. The dependent variables were the successful completion …
Satellite-Based Phenology And Climate Anomaly Analysis In Evaluating The Response Of Puerto Rico And The U.S. Virgin Islands Tropical Forests To The 2015-2016 Drought, Sean Fleming
Cal Poly Humboldt theses and projects
The health and overall resilience of tropical forest ecosystems are closely tied to the timing of phenological events. One must consider how forests react to significant climate anomalies to forecast the possible effects of climate change. This research study utilized U.S. Forest Service Forest Inventory Analysis (FIA) plot-level data and Landsat satellite data together to determine if these datasets are valuable techniques to understand the impacts of the 2015-2016 drought on Puerto Rico and the U.S. Virgin Islands (PRVI). I did remote sensing analysis on PRVI to produce repaired and near cloud-free satellite imagery, producing dozens of phenometrics of all …
Climate Change, Policy Paralysis, And A Nuclear Waste Island? Exploring Perceptions Of Risk, Trust, And Community Agency In Navigating Uncertain Futures Facing Humboldt Bay's Spent Nuclear Fuel Storage Site, Alexander Brown
Cal Poly Humboldt theses and projects
Climate and coastal hazards threaten the long-term viability of indefinite in-situ nuclear waste storage in the U.S., especially at vulnerable “stranded” sites like Humboldt Bay, California. The national policy framework is fundamentally incompatible with emergent climate realities and does not adequately accommodate uncertainty, localized hazard conditions, and the sociocultural and political dynamics that manifest in diverse and contested public arenas. I interviewed 21 community-experts working at the intersection of climate change and nuclear waste, and co-facilitated three scenario planning workshops to gather insights on how to responsibly manage Humboldt Bay’s nuclear waste in a climate-altered world. Qualitative findings indicate variation …
Assessing Community Perspectives To Inform Kelp Forest Restoration And Management: The Case Of Mendocino Coast, California, Jocelyn Enevoldsen
Assessing Community Perspectives To Inform Kelp Forest Restoration And Management: The Case Of Mendocino Coast, California, Jocelyn Enevoldsen
Cal Poly Humboldt theses and projects
In coastal Mendocino County, California, a multi-year marine heatwave event kicked off a dramatic ecosystem transformation that led to a near-total loss of bull kelp forests. People who relied on the local kelp ecosystems were affected and facing decisions about how to respond to the kelp ecosystem transformation. Rigorous assessments that are inclusive of local perspectives, values, and preferences could inform efforts related to kelp forest ecosystem management, conservation, and restoration. My research focused on answering the following questions: (1) What are the ways that people are connected to kelp ecosystems on the Mendocino coast? (2) What are community members’ …
Examining The Drivers Of Nocturnal Behavior Of Pikas At Lower Elevations In Lassen National Forest, California, Evan Burnett
Examining The Drivers Of Nocturnal Behavior Of Pikas At Lower Elevations In Lassen National Forest, California, Evan Burnett
Cal Poly Humboldt theses and projects
The American pika (Ochotona princeps) is a charismatic mammal species adapted to occupy rockslides and boulder fields in western North America. Historically monitored due to their climate sensitivity, pikas have experienced extirpations along their lower range margins—driven by chronic and acute temperature stress—prompting increased concern and monitoring over the risks posed by anthropogenic climate change. Traditionally considered an alpine species, pikas occupy a wide range of elevations, with those at lower elevations exhibiting higher rates of nocturnality than their counterparts at higher elevations. Temperature is hypothesized to be the driver, but this has yet to be confirmed. Pikas …
Evaluating The Trojan Y Chromosome Strategy For The Removal Of Invasive Sacramento Pikeminnow From The Eel River, Ca, Alexander W. Juan
Evaluating The Trojan Y Chromosome Strategy For The Removal Of Invasive Sacramento Pikeminnow From The Eel River, Ca, Alexander W. Juan
Cal Poly Humboldt theses and projects
The recent introduction and spread of Sacramento Pikeminnow (Ptychocheilus grandis) in Northern California’s Eel River Basin represents a significant threat and impediment to the recovery of several threatened native fish species. This study was undertaken to evaluate the Trojan Y Chromosome Strategy (TYC) for the extirpation of pikeminnow from the basin. TYC is a genetic biocontrol method that relies on the production and stocking of fish with YY sex chromosomes, which may be phenotypically male (YY male) or female (YY female). These YY fish produce all-male offspring when mating with their wild conspecifics and TYC can lead to …
Assessing The Effects Of Remaining Northern California Kelp Forest Mesopredators On Purple Sea Urchin Abundance, Distribution, And Feeding Activity, Sandra E. Traverso
Assessing The Effects Of Remaining Northern California Kelp Forest Mesopredators On Purple Sea Urchin Abundance, Distribution, And Feeding Activity, Sandra E. Traverso
Cal Poly Humboldt theses and projects
Kelp forests are threatened by regional abiotic and biotic stressors, including overgrazing by sea urchins. On the north coast of California, purple sea urchins (Strongylocentrotus purpuratus) are prolific grazers of kelp and with the regional extinction of their main predator (sunflower stars, Pycnopodia helianthoides), it is unknown whether any remaining mesopredators could exert top-down control of purple urchin populations. Other known predators of purple urchins in northern California include rock crabs, which have been shown to control sea urchin populations in Atlantic urchin barrens and indirectly cause phase shifts back to kelp forests. Yet, little is known …
Analyzing Stakeholder Perceptions On Biogas Production Incentives Under California’S Low Carbon Fuel Standard, Emily Read
Cal Poly Humboldt theses and projects
Accounting for more than half of California’s methane emissions, the dairy and livestock sector has become a central focus for the state’s emission reduction efforts. As a leader in climate policy, California’s approach to addressing agricultural methane emissions has the potential to shape the future of livestock agriculture on a national and global scale. The state has prioritized anaerobic digesters as the primary strategy for addressing livestock methane, a decision that has been both widely contested and strongly supported by stakeholders. This thesis investigates stakeholder perceptions on livestock biogas under California’s Low Carbon Fuel Standard (LCFS) using interview and survey …
Lung Cancer Clustering By Identification Of Similarities And Discrepancies Of Dna Copy Numbers Using Maximal Information Coefficient, Nezamoddin N. Kachouie, Wejdan Deebani, Meshal Shutaywi, David C. Christiani
Lung Cancer Clustering By Identification Of Similarities And Discrepancies Of Dna Copy Numbers Using Maximal Information Coefficient, Nezamoddin N. Kachouie, Wejdan Deebani, Meshal Shutaywi, David C. Christiani
Mathematics and System Engineering Faculty Publications
Lung cancer is the second most diagnosed cancer and the first cause of cancer related death for men and women in the United States. Early detection is essential as patient survival is not optimal and recurrence rate is high. Copy number (CN) changes in cancer populations have been broadly investigated to identify CN gains and deletions associated with the cancer. In this research, the similarities between cancer and paired peripheral blood samples are identified using maximal information coefficient (MIC) and the spatial locations with substantially high MIC scores in each chromosome are used for clustering analysis. The results showed that …
Spatiotemporal Bayesian Machine Learning For Estimation Of An Empirical Lower Bound For Probability Of Detection With Applications To Stationary Wildlife Photography, Mohamed Jaber, Robert D. Breininger, Farag Hamad, Nezamoddin N. Kachouie
Spatiotemporal Bayesian Machine Learning For Estimation Of An Empirical Lower Bound For Probability Of Detection With Applications To Stationary Wildlife Photography, Mohamed Jaber, Robert D. Breininger, Farag Hamad, Nezamoddin N. Kachouie
Mathematics and System Engineering Faculty Publications
An important parameter in the monitoring and surveillance systems is the probability of detection. Advanced wildlife monitoring systems rely on camera traps for stationary wildlife photography and have been broadly used for estimation of population size and density. Camera encounters are collected for estimation and management of a growing population size using spatial capture models. The accuracy of the estimated population size relies on the detection probability of the individual animals, and in turn depends on observed frequency of the animal encounters with the camera traps. Therefore, optimal coverage by the camera grid is essential for reliable estimation of the …
Studying The Role Of Novel Carbon Nano Tubes As A Therapeutic Agent To Treat Triple Negative Breast Cancer (Tnbc) - An In Vitro And In Vivo Study, Kamal Asadipour, Narendra Banerjee, Jazmine Cuffee, Karrington Perry, Shennel Brown, Anasua Banerjee, Erik Armstrong, Stephen Beebe, Hirendra Banerjee
Studying The Role Of Novel Carbon Nano Tubes As A Therapeutic Agent To Treat Triple Negative Breast Cancer (Tnbc) - An In Vitro And In Vivo Study, Kamal Asadipour, Narendra Banerjee, Jazmine Cuffee, Karrington Perry, Shennel Brown, Anasua Banerjee, Erik Armstrong, Stephen Beebe, Hirendra Banerjee
Bioelectrics Publications
Triple Negative Breast Cancer (TNBC) is a malignant cancer with a very high mortality rate around the world. African American(AA) women are 28% more likely to die from triple-negative breast cancer (TNBC) than white women with the same diagnosis. AA patients are also more likely to be diagnosed at a later stage of the disease and have the lowest survival rates for any stage of diagnosis; There are very few existing anti TNBC drugs with therapeutic efficacy hence newer anti TNBC drug design and investigation is needed. Carbon Nano Tubes(CNT) in recent years have shown effective anti-cancer properties in various …
Synergistic Effects Of Nanosecond Pulsed Plasma And Electric Field On Inactivation Of Pancreatic Cancer Cells In Vitro, Edwin A. Oshin, Zobia Minhas, Ruben M. L. Colunga Biancatelli, John D. Catravas, Richard Heller, Siqi Guo, Chunqi Jiang
Synergistic Effects Of Nanosecond Pulsed Plasma And Electric Field On Inactivation Of Pancreatic Cancer Cells In Vitro, Edwin A. Oshin, Zobia Minhas, Ruben M. L. Colunga Biancatelli, John D. Catravas, Richard Heller, Siqi Guo, Chunqi Jiang
Bioelectrics Publications
Nanosecond pulsed atmospheric pressure plasma jets (ns-APPJs) produce reactive plasma species, including charged particles and reactive oxygen and nitrogen species (RONS), which can induce oxidative stress in biological cells. Nanosecond pulsed electric field (nsPEF) has also been found to cause permeabilization of cell membranes and induce apoptosis or cell death. Combining the treatment of ns-APPJ and nsPEF may enhance the effectiveness of cancer cell inactivation with only moderate doses of both treatments. Employing ns-APPJ powered by 9 kV, 200 ns pulses at 2 kHz and 60-nsPEF of 50 kV/cm at 1 Hz, the synergistic effects on pancreatic cancer cells (Pan02) …