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Molecular Dynamics Study Of Alpha-Synuclein Repeat Mutations And Sars-Cov-2 Nucleocapsid Linker Phosphorylation, Coby Yeung Jan 2024

Molecular Dynamics Study Of Alpha-Synuclein Repeat Mutations And Sars-Cov-2 Nucleocapsid Linker Phosphorylation, Coby Yeung

Theses and Dissertations

The study aimed to utilize molecular dynamics (MD) simulation to investigate intrinsically disordered protein (IDP) molecules and regions, focusing on IDPs such as alpha-synuclein and the SAR-CoV-2 nucleocapsid linker segment and their variants. Methodologically, the research employed MD simulation with implicit solvent methods, GaMD enhanced sampling, Python-based analysis, and VMD visualization. The study's significance lies in revealing structural dynamics insights of IDP regions. Key findings include the average structures of target sequences from k-means clustering analysis. The impact of mutations in alpha-synuclein KTKEGV repeat mutations is also revealed. Mutations introducing hydrophobic residues, like KGV and KLK, increased surface hydrophobicity, with …


Wright State University Magazine, 2024, Wright State Alumni Association And Wright State Foundation Jan 2024

Wright State University Magazine, 2024, Wright State Alumni Association And Wright State Foundation

Wright State University Magazine

Fifty-two page issue of the Wright State University Magazine. This magazine is published once a year and focuses on news related to Wright State alumni, faculty, staff, and friends of the university.


Clients In The Driver’S Seat, Not Asleep At The Wheel: A Qualitative Study Of The Client Role In Transpersonal Psychotherapy, Phyllis Alongi, Jenny Wade Jan 2024

Clients In The Driver’S Seat, Not Asleep At The Wheel: A Qualitative Study Of The Client Role In Transpersonal Psychotherapy, Phyllis Alongi, Jenny Wade

International Journal of Transpersonal Studies Advance Publication Archive

Despite the power of the therapeutic alliance in effective therapy and its larger-thanthe- individuals-comprising-it (transpersonal) qualities, the client’s contribution to the therapeutic process has been largely overlooked in both conventional and transpersonal literatures. This study asked 35 transpersonal practitioners, what is the role of the client in transpersonal psychotherapy? The study examined client traits, attitudes and role demands in Jungian therapy, sandplay therapy, dream analysis, guided imagery, regression and hypnotherapy, nondual psychotherapy, and psychedelic-assisted psychotherapy using inductive thematic analysis. The results distinguish transpersonal therapy clients from conventional ones, indicating that the transpersonal client role characteristics and behaviors are unavoidably more …


Smokable "Vine Of The Dead": Two Case Studies Of Experiencers Of Both Changa And Near-Death Experiences, Pascal Michael, David Luke, Oliver Robinson Jan 2024

Smokable "Vine Of The Dead": Two Case Studies Of Experiencers Of Both Changa And Near-Death Experiences, Pascal Michael, David Luke, Oliver Robinson

International Journal of Transpersonal Studies Advance Publication Archive

Introduction: Virtually no studies have looked at psychopharmacological combinations as models of the near-death experience (NDE), which is inadequate given the evidently complex neurochemistry occurring near- or at death. An example of such a combination is ‘changa’, a smoked mixture of the psychedelic N,N-DMT and monoamine oxidase inhibitor (MAOI)-containing plants, and as such has been referred to as ‘smokable ayahuasca’ (vine of the dead). Only very few studies, yet not systematically, have included experiencers of both NDEs and psychoactive substances. Methods: Two case studies are presented of individuals who have experienced both a near-death experience and a changa experience, making …


Lotería: Hybrid Narrative Of A Transracial Adoptee, Dani F. Sarta Jan 2024

Lotería: Hybrid Narrative Of A Transracial Adoptee, Dani F. Sarta

Graduate Thesis and Dissertation 2023-2024

Lotería is a hybrid poetry collection that follows the life of the speaker as a queer, Hispanic transracial adoptee raised by a conservative Catholic family in Central Florida, focusing on their struggle to fit into the binaries assigned to and expected of them across religion, race, gender, and sexuality. This collection is separated into three sections, each expanding on the one before as the speaker journeys through life, exploring their identity and their connection with the world around them. In the first section, poems such as "(Non)Binary Star" and "Size 6 Woman Size 18 Daughter" sift through the speaker's conflict …


Are Parental Nonstandard Work Schedules A Barrier To Their School Involvement?, Kess Ballentine, Alejandra Ros Pilarz Jan 2024

Are Parental Nonstandard Work Schedules A Barrier To Their School Involvement?, Kess Ballentine, Alejandra Ros Pilarz

Social Work Faculty Publications

Parental school involvement is consistently associated with better child development outcomes. Although parental work schedules are expected to shape school involvement, little empirical research examines this relationship. Using nationally representative data from the Early Childhood Longitudinal Study, Kindergarten Cohort 2010-11, (N=6,047), we estimated associations between parents’ work schedules and multiple indicators of school involvement. Compared to daytime schedules, flexible variable schedules were associated with more parental school involvement. Working a regular nonstandard schedule or employer-set variable schedule was not associated with school involvement, except that working nights was associated with attending fewer school events. We found limited evidence of heterogeneity …


Orgsp Quarterly: An Orgsp Newsletter From Lincoln Memorial University, Vol 9.1, Lincoln Memorial University, Office Of Research Grants And Sponsored Projects Jan 2024

Orgsp Quarterly: An Orgsp Newsletter From Lincoln Memorial University, Vol 9.1, Lincoln Memorial University, Office Of Research Grants And Sponsored Projects

ORGSP Quarterly

This quarter's issue focuses on winter research. Learn about the excellent work of LMU's faculty, staff, and students.


Hough, Bertha, Rowan County Genealogical Society. Jan 2024

Hough, Bertha, Rowan County Genealogical Society.

Rowan County Genealogy Collection

Genealogy of the Bertha Ross Hough, née Poage family in Rowan County, Kentucky.


The Importance Of Luke 3, Patrick Russell Jan 2024

The Importance Of Luke 3, Patrick Russell

Obsculta

This paper attempts to show the literary and theological significance of the genealogy in Luke 3. Though the text can be read as merely something to convey facts; the textual placement and the theological themes at work within the genealogy in relation to Luke-Acts are not arbitrary. In light of the overall use of genealogies in the ancient near east this pericope becomes something far more dynamic than it might otherwise seem upon first glance.


Encountering Artificial Intelligence: Ethical And Anthropological Explorations., Noreen L. Herzfeld, Matthew J. Gaudet, Paul Scherz, Jordan J. Wales Jan 2024

Encountering Artificial Intelligence: Ethical And Anthropological Explorations., Noreen L. Herzfeld, Matthew J. Gaudet, Paul Scherz, Jordan J. Wales

School of Theology and Seminary Faculty Books

What does it mean to consider the world of AI through a Christian lens? Rapid developments in AI continue to reshape society, raising new ethical questions and challenging our understanding of the human person. Encountering Artificial Intelligence draws on Pope Francis's discussion of a culture of encounter and broader themes in Catholic social thought in order to examine how current AI applications affect human relationships in various social spheres and offers concrete recommendations for better implementation. The document also explores questions regarding personhood, consciousness, and the kinds of relationships humans might have with even the most advanced AI. Through these …


Environmental Law: Wolf Law, Jesse Honig, David Takacs Jan 2024

Environmental Law: Wolf Law, Jesse Honig, David Takacs

The Judges' Book

No abstract provided.


Doing A Good Search: Basic Rules And Search Tips, Roy E. Brown Jan 2024

Doing A Good Search: Basic Rules And Search Tips, Roy E. Brown

VCU Libraries Faculty and Staff Publications

This updated handout, previous version published in 2023, serves as a reference for individuals learning effective database search practices. It covers fundamental search principles, including Boolean operators, question types, and potential databases for various questions for assignments or in the clinical environment. Notably, this version incorporates a diagram illustrating the search process.

Remember, the search process is iterative, involving repeated cycles of refinement. Your approach will vary depending on the specific question you're trying to answer.

Update of Doing a Good Search: Basic Rules and Search Tips (2023)

The original version appeared in the following article:

McGrath, J. M., Brown, …


How Viable Is Viability? Artificial Womb Technology And The Threat To Abortion Access, James E. Brown Jan 2024

How Viable Is Viability? Artificial Womb Technology And The Threat To Abortion Access, James E. Brown

Michigan Journal of Gender & Law

The viability standard plays an important role in abortion access around much of the United States. In fact, before the Dobbs decision, the viability standard was the constitutional gatekeeper to abortion access and was uniform across the entire nation. Unfortunately, the Supreme Court has removed the constitutional right to abortion altogether. Nevertheless, I will provide an argument as to why Dobbs does not signal the end of viability-based abortion around the U.S. I will prove the importance of the viability standard even in a post-Dobbs society, highlighting its operation within various state laws, such as Michigan’s Prop. 3, as well …


Child Sacrifices: The Precarity Of Minors’ Autonomy And Bodily Integrity After Dobbs, Teri Dobbins Baxter Jan 2024

Child Sacrifices: The Precarity Of Minors’ Autonomy And Bodily Integrity After Dobbs, Teri Dobbins Baxter

Scholarly Works

In Dobbs v. Jackson Women’s Health Organization, the Supreme Court held that there is no constitutional right to abortion. The decision has had a devastating impact on people seeking abortions in many states, and it will have an even more profound effect on the rights and lives of minors. Pregnant minors face greater risks than pregnant adults when they are forced to continue a pregnancy that can harm their physical and mental health and their educational and financial futures. Very young minors are incapable of consenting to the sexual acts that result in pregnancy, but many states require even these …


Aba Standard 303(C) And Divisive Concepts Legislation And Policies: Challenges And Opportunities, Sherley Cruz, Becky L. Jacobs, Karen L. Tokarz, Kendall Kerew, Andrew King-Ries, Carwina Weng Jan 2024

Aba Standard 303(C) And Divisive Concepts Legislation And Policies: Challenges And Opportunities, Sherley Cruz, Becky L. Jacobs, Karen L. Tokarz, Kendall Kerew, Andrew King-Ries, Carwina Weng

Scholarly Works

This article by six clinicians discusses the challenges and opportunities of new ABA Standard 303 (c), including the implications of and interactions between Standard 303(c) and “divisive concepts” laws and other threats to representation, academic freedom, and free speech in legal education. The article also highlights the intersection of Standard 303(c) and Standard 303(b)(3), which addresses professional identity formation; discusses opportunities to adapt current curriculum and teaching and create new curricular responses to meet the new accreditation standards and interpretations; and explores ways to resist increasing limitations and find a supportive academic community to sustain hope and resilience.


Antitrust & Ai Supply Chains, Maurice E. Stucke, Ariel Ezrachi Jan 2024

Antitrust & Ai Supply Chains, Maurice E. Stucke, Ariel Ezrachi

Scholarly Works

Will AI technology disrupt the current Big Tech Barons, foster competition, and ensure future disruptive innovation that improves our well-being? Or might the technology help a few ecosystems become even more powerful?

To explore this issue, our paper outlines the current digital market dynamics that lead to winner-take-most-or-all ecosystems. After examining the emerging AI foundation model supply chain, we consider several potential antitrust risks that may emerge should certain layers of the supply chain become concentrated and firms extend their power across layers. But the anticompetitive harms are not inevitable, as several countervailing factors might lessen or prevent these antitrust …


Occupational Therapy’S Role In Addressing The Mental Health Of Transitioning Postsecondary Students, Katie Koxlien, Amorelle Upton, Kiley Washnieski Jan 2024

Occupational Therapy’S Role In Addressing The Mental Health Of Transitioning Postsecondary Students, Katie Koxlien, Amorelle Upton, Kiley Washnieski

Critically Appraised Topics

There is an increasing concern for mental health in university students transitioning to postsecondary education. For the purposes of this study, we were concerned with the overall mental health of university students, not specific to diagnosed mental illnesses. Mental health is “a state of mental well-being that enables people to cope with the stresses of life, realize their abilities, learn well and work well, and contribute to their community” (World Health Organization, 2022, para. 1). This may impact the individual’s ability to function on a daily basis and interact with others within their educational setting. The role of a student …


Can Functional Traits Predict Turnover Of Alpine Plant Species In Yosemite National Park?, Brooke L. Wallasch Jan 2024

Can Functional Traits Predict Turnover Of Alpine Plant Species In Yosemite National Park?, Brooke L. Wallasch

Biological Sciences

Alpine species are a useful tool for predicting the effects of climate change on lowland species. A growing body of research has begun assessing the question of how alpine species will change in response to changing climate. In the study of alpine plant species, some researchers have begun exploring the idea that functional traits could be predictive of turnover in alpine plant communities. In this study, I used a species’-level approach to assess the ability of six functional traits (vegetative height, generative height, leaf thickness, leaf area, leaf dry weight, specific leaf area) to predict species turnover in alpine plants …


Assessing The Relationship Between Intercultural Competence And Inclusion Competence: An Empirical Study Of Faculty At Higher Education Institutions In The United States, Casey Aldrich Jan 2024

Assessing The Relationship Between Intercultural Competence And Inclusion Competence: An Empirical Study Of Faculty At Higher Education Institutions In The United States, Casey Aldrich

Dissertation Collection

This dissertation explores the relationship between faculty’s intercultural competence and their inclusion competence within the context of Higher Education Institutions (HEIs) in the United States. The construct of intercultural competence refers to effectiveness in engaging people across cultural differences, while inclusion competence focuses on competences critical for effective performance related to inclusive behavior. Studying these two constructs together provides insight into the potential of intercultural education to contribute to Diversity, Equity, and Inclusion (DEI) efforts at US HEIs, especially in terms of fostering inclusive learning environments. Drawing from data collected using two psychometric assessments – the Intercultural Effectiveness Scale (IES) …


Struggling To Recover Or Recovering The Struggle: A Critical Examination Of Recovery Narratives As Discourses-In-Practice For People Suffering From Postpartum Depression, Alanna R. Miller, Alexandru Stana Jan 2024

Struggling To Recover Or Recovering The Struggle: A Critical Examination Of Recovery Narratives As Discourses-In-Practice For People Suffering From Postpartum Depression, Alanna R. Miller, Alexandru Stana

Communication Studies Faculty Works

Postpartum depression is a prevalent condition, and preliminary data suggest that the COVID-19 pandemic further increased its incidence. Building on scholarship that has shown the value of exploring patients’ narratives for diagnosis and treatment, this study examines narratives of recovery in an online support forum, using theories of narrative identity. An online forum with 64 participants suffering from postpartum depression was analyzed according to grounded theory. A thematic analysis uncovered two dominant narratives: the full recovery or inevitable progress narrative, and the cyclical recovery or struggle as norm narrative. This study illustrates the complicated interaction between medical institutions, recovery narratives, …


Common Data Set 2023-2024, Clemson University Jan 2024

Common Data Set 2023-2024, Clemson University

Common Data Sets

No abstract provided.


Feasibility In Embedding Charismatic Leadership Strategies Into Social Work Applications, Lana Grinev Jan 2024

Feasibility In Embedding Charismatic Leadership Strategies Into Social Work Applications, Lana Grinev

Doctorate of Social Work (DSW) Capstones 2024-

The six key charismatic leadership characteristics (i.e., communication, compassion, confidence, creativity, determination, and vision) are shown methodologically, thematically, and theoretically to provide organizations and systems with desired outcomes and results. This short generic qualitative inquiry review will provide evidence that the six key charismatic leadership characteristics are currently systematically employed in multiple diverse occupational and research settings to improve followers' goals and responses. Aligning existing leadership strategies to complement the six main charismatic leadership characteristics over recommended occupational competencies finds that charismatic leadership is a parallel process of leadership and management for social workers and other occupational domains, particularly within …


Breaking Down Barriers: Improving Asian American Mental Health, Zhen Yang Jan 2024

Breaking Down Barriers: Improving Asian American Mental Health, Zhen Yang

Doctorate of Social Work (DSW) Capstones 2024-

Mental illness is a significant concern affecting millions of people in the United States every year. According to the National Alliance on Mental Illness (NAMI), one in five U.S. adults and one in six U.S. youth experience a mental health illness yearly. Shockingly, 50% of all lifetime mental illnesses begin by the age of 14, and 75% by the age of 24. According to the Centers for Disease Control and Prevention (CDC, 2023), 37% of Asian American adults reported that their mental health status was "not good." Astonishingly, 73.1% of these individuals did not receive treatment, compared to 56.7% of …


Sacred Heart University Magazine, Volume 6, Issue 1, Sacred Heart University Jan 2024

Sacred Heart University Magazine, Volume 6, Issue 1, Sacred Heart University

Sacred Heart University Magazine

No abstract provided.


The Effectiveness Of The Chinese Communist Party’S Guerrilla Warfare During The Second Sino Japanese War, 1937-1945, Paul Collins Jan 2024

The Effectiveness Of The Chinese Communist Party’S Guerrilla Warfare During The Second Sino Japanese War, 1937-1945, Paul Collins

Undergraduate Review

During the Second Sino-Japanese War, the Chinese Communist Party prioritized preserving widespread support while inflicting significant damage on Japanese forces despite facing formidable opposition, leading to the development of specific strategies to meet these goals. Ultimately, the Communists’ adoption of guerrilla warfare became the hallmark of their strategy, influencing the post-war perception of Communist success versus Nationalist failure. Extensive research has revealed that the Communists’ guerrilla warfare was overall highly successful, soundly developed, and instrumental in achieving China’s victory over Japan, due to strategies that had proven to have little recourse in combat.


Ut Permian Basin Graduate Catalog 2024-2025, The University Of Texas Permian Basin Jan 2024

Ut Permian Basin Graduate Catalog 2024-2025, The University Of Texas Permian Basin

Course Catalogs

No abstract provided.


Fisheries Research Report No. 346: West Coast Demersal Scalefish Resource Synopsis 2024, Emily A. Fisher, David Fairclough Jan 2024

Fisheries Research Report No. 346: West Coast Demersal Scalefish Resource Synopsis 2024, Emily A. Fisher, David Fairclough

Fisheries Research Reports

The West Coast Demersal Scalefish Resource (WCDSR) comprises over 100 species that inhabit inshore (20-250 m deep) and offshore ( > 250 m deep) waters of the West Coast Bioregion (WCB; north of Kalbarri to east of Augusta).

The WCB is predominantly a temperate oceanic zone with these waters influenced by the Leeuwin Current that transports warm, low-nutrient water southward along the western edge of the continental shelf.

To monitor and assess the WCDSR, indicator species have been selected using a risk-based approach that considers their inherent vulnerability to fishing, level of targeting and catch taken by fishers, and the amount …


Obstetric Fistulas In Sub-Saharan Africa, Katie Whitcomb Jan 2024

Obstetric Fistulas In Sub-Saharan Africa, Katie Whitcomb

Ballard Brief

An obstetric fistula is a hole in the vaginal canal, either to the bladder or the rectum. It is a childbirth complication caused by obstructed, prolonged labor. Sub-Saharan African mothers are particularly vulnerable to fistulas if they are poor, rural living, or young. Additionally, cultural barriers, distrust of Western health facilities, and birthing traditions play a role in the pervasiveness of obstetric fistulas in modernity. A hole in the bladder or rectum leads to loss of control over urination or defecation. However, there are secondary consequences, such as mental illness and social stigma, that cause just as much suffering as …


Bridgewater College Catalog, Session 2024-25, Bridgewater College Jan 2024

Bridgewater College Catalog, Session 2024-25, Bridgewater College

Bridgewater College Catalogs

No abstract provided.


Trees And The Love Of God, David M. Belnap, Nalini M. Nadkarni Jan 2024

Trees And The Love Of God, David M. Belnap, Nalini M. Nadkarni

Interpreter: A Journal of Latter-day Saint Faith and Scholarship

Trees play real and metaphorical roles in the beliefs and holy scriptures of many world religions, and believers and non-believers throughout the world are uplifted spiritually by trees. In the Book of Mormon, a tree with delicious, sweet fruit appeared in two visions and one parable. Respectively, the tree represents the love of God as seen through the life and sacrifice of Jesus Christ and symbolizes spiritual growth as one experimentally nourishes faith from a seed. Trees and fruit in the world around us can remind us of important lessons from these teachings and help keep us focused on the …