Digital Commons Network^™

N-(2-Aminobenzoyl)Benzotriazole Mediated Synthesis Of 3- Acyl-2-Alkyl(Aryl)-4-Hydroxyquinolines And 3-Acylamino-4(3h) Quinazolinones, İlbilge Merve Şenol, Sevtem Gökbulut Satioğlu, İlhami Çeli̇k

Turkish Journal of Chemistry

New methods have been developed for the synthesis of the substituted quinolines and quinazolinones derivatives by utilizing N-(2-aminobenzoyl)benzotriazoles under mild reaction conditions. 3-Acyl-2-alkyl(aryl)-4-hydroxyquinolines were obtained in modarete yields by the reaction of N-(2-aminobenzoyl)benzotriazoles and diketones in the presence of tert-BuOK. 3-Acylamino-4(3H) quinazolinones were obtained in good yields via N-(2-aminobenzoyl)benzotriazoles, orthoester and hyrazides in one-pot.

Synthesis And Characterization Of Surface-Modified Magnetic Mesoporous Silicate Materials For Phosphate Adsorption, Ayşegül Gençer, Burcu Uysal Karataş, Önder Topel, Nadir Ki̇raz

Turkish Journal of Chemistry

The magnetic mesoporous silica material, Mag-MCM-41, was synthesized by coating magnetite (Fe3O4) nanoparticles with a mesoporous material called MCM-41. Mag-MCM-41 and modified nanomaterials Mag-MCM-41-NN and Mag-MCM-41-NN-Fe+3 which were modified with aminopropyl functional groups. In water and wastewater, phosphate anions are considered significant contaminants due to their detrimental impact on the environment. They promote the growth of algae, leading to eutrophication. The purpose of this study is to investigate the removal of phosphate anions from aqueous solutions using modified magnetic silica particles. The Mag-MCM-41 material exhibits hexagonal properties and belongs to the class of “mesoporous” materials. It has a surface area …

An Efficient One-Pot And Simple Multicomponent Approach To The Synthesis Of Highly Functionalized Furans Containing Dialkyl Phenol, Fourogh Jalili Milani, Mahmoud Nassiri, Jaber Salehzadeh

Turkish Journal of Chemistry

In this study, arylglyoxals, acetylacetone, and 2,6-dimethyl phenol or 2,6-di-tert-butyl phenol are combined to efficiently synthesize a series of 1-(4-(3,5-dialkylphenyl)-2-methyl-5-phenylfuran-3-yl) ethan-1-one derivatives in excellent yields. These reactions were carried out in acetone at reflux under catalyst-free conditions in the presence of triethylamine as a base for 3 h. NMR, FT-IR, EI-MS, and elemental studies were used to characterize the products' structural characteristics. The present study has also several benefits, such as excellent yields and the ease of workup procedure, making it an appealing, practical, and acceptable one-pot method for producing functionalized derivatives of dialkyl furan.

Voltammetric Measurement Of Catechol-O-Methyltransferase Inhibitor Tolcapone In The Pharmaceutical Form On The Boron-Doped Diamond Electrode, Musa Kiran, Yavuz Yardim

Turkish Journal of Chemistry

This study presents an electroanalytical approach to measure the catechol-O-methyltransferase (COMT) inhibitor tolcapone (TOL) using a boron-doped diamond (BDD) electrode. The application of cyclic voltammetry (CV) technique revealed that TOL exhibited a distinct, diffusion-controlled, irreversible anodic peak at a potential of approximately +0.71 V (vs. Ag/AgCl) in a 0.1 mol L–1 phosphate buffer solution (PBS) with a pH of 2.5. The oxidation of TOL is highly dependent on the pH and supporting electrolytes. Based on the data obtained from the pH investigation, a proposed mechanism for the electro-oxidation of TOL is suggested. Using the square wave voltammetry (SWV) technique, a …

Alcohol-Mediated Changes In Myoblast Hif-1Α Protein Expression And Relationships With Decreased Differentiation Capacity: A Preliminary Analysis, Colby Newman, Alexandra Khartabil, Matthew Dileo, Zenaida Villalba, Danielle Levitt

International Journal of Exercise Science: Conference Proceedings

Alcohol-mediated myopathy, or decreased functional skeletal muscle (SKM) mass, is highly prevalent among individuals with alcohol use disorder (AUD). SKM regeneration aids in maintaining functional SKM muscle mass. Using an in vitro (myoblast) model, we showed that alcohol (EtOH) treatment decreases differentiation capacity in association with decreased glycolytic function, but the underlying mechanisms are incompletely understood. Hypoxia-inducible factor (Hif)-1α is a transcription factor that promotes glycolysis, the bioenergetic pathway that primarily supports myoblast energetic demands. EtOH can increase or decrease Hif-1α expression in various cell types, but this has not been assessed in myoblasts. PURPOSE: Test the hypothesis that alcohol …

Within-Day Reliability Of Submaximal Running Economy Testing, Garrett M. Oehlert, Eric J. Jones, Dustin P. Joubert

International Journal of Exercise Science: Conference Proceedings

Running economy (RE), a measure of oxygen consumption associated with a given intensity, has been identified as a critical component of endurance performance. Acute, same-day interventions, such as alterations in footwear, have been shown to significantly impact RE. Quantifying the reliability of within-day RE measures would determine minimal detectable differences that could be expected when testing footwear and other acute interventions. PURPOSE: Assess the within-day reliability of RE testing on a calibrated metabolic measurement system. METHODS: Trained male distance runners (n=10) were recruited to perform 4 × 5-minute trials under constant conditions (set speed and in their own …

Salivary C-Reactive Protein And Cortisol Analysis In Collegiate Female Lacrosse Athletes During A 2-Game Week, Kelsi R. Lambright, Stephanie Mathews, Jennifer A. Bunn

International Journal of Exercise Science: Conference Proceedings

Cortisol (CORT) and C-reactive protein (CRP) are two indicators of stress and are linked to tissue inflammation and illness. Increased stress and inflammation have been shown to decrease cognitive functioning, leading to diminished performance for athletes. Subjectively, athletes indicate fluctuations in stress, but few studies have assessed the physiological response of training and competition in elite female athletes. PURPOSE: The primary aim was to assess the acute response of CORT and CRP in Division I female lacrosse athletes during a high-stress week, including two games and three practices during the competitive season. The secondary aim was to assess the …

Impact Of Menstrual Cycle On Resting And Postprandial Metabolism In Recreationally Active, Eumenorrheic Females, Adelle Kanaan, Emma Ware, Erika Zoellner, Catherine Mbango, Deltra Muoki, Wayne Brewer, Mindy Patterson, Derek Miketinas, Siddhartha Angadi, Glenn A. Gaesser, Wesley Tucker

International Journal of Exercise Science: Conference Proceedings

Changes in estrogen and progesterone across the menstrual cycle impact many biological systems including resting and postprandial metabolism. PURPOSE: To investigate whether menstrual cycle phase impacted resting and postprandial energy expenditure (EE) and substrate utilization in recreationally active, eumenorrheic females. METHODS: In this study, 8 eumenorrheic females (mean±SD age: 33±8 years, BMI: 22.5±2.2 kg/m²; VO_2max: 36.9±3.8 ml/kg/min) had resting energy expenditure (REE) and substrate utilization continuously measured with indirect calorimetry for 45 min at rest after an overnight fast, and for 3 h after a mixed meal (490 kcal, 53% carbohydrate, 31% fat, 20% …

Driving Entrainment Of Locomotor And Respiratory Systems To Determine Metabolic Efficiency, Michael T. Young, Jennifer M. Yentes, Kuanting Chen

International Journal of Exercise Science: Conference Proceedings

Many biological rhythms, including breathing and locomotor rhythms, are interconnected through a phenomenon known as coupling. Locomotor respiratory coupling (LRC) is quantified using a ratio of stride cycles to breaths. For example, an entrained LRC ratio of two strides to one breathing cycle, is a typical ratio humans use while walking. While various ratios have been recorded, previous research has suggested that not deviating from a particular ratio is associated with low energy expenditure. However, recent research challenges the assumption that stronger LRC correlates with lower energy expenditure, but rather, LRC variability is associated with lower energy expenditure. In addition, …

Release Of Microrna15a/16 From Skeletal Muscle During Exercise Regulates Proteostasis In Muscle And Cancer, Patrick Ryan, Selina Uranga, James D. Fluckey

International Journal of Exercise Science: Conference Proceedings

Proteostasis, the intricate process of maintaining the proteome, is a critical matter for cellular health. The regulation of the multiple intersecting metabolic pathways comprising the proteostatic network is correspondingly complex and incompletely understood; however, a new and intriguing candidate in understanding this process has emerged in the form of microRNA (miRNA), small RNA species which are capable of regulating hundreds of genes at once by binding to and degrading mRNA transcripts. We have previously shown that muscle contraction results in the release of two miRNA species (miR15a/16) from skeletal muscles, and that a perfusate rich in these miRNAs slows growth …

Differences In Skeletal Muscle Oxygenation Of Vastus Laterals And Gastrocnemius During Exhaustive Exercise, Kaitlyn Gingell, Ricardo Torres, Jordan Ledington, Leroy Bolden, Tomas Chapman-Lopez, Dylan Willburn, Meena Meiyyappan, Adam Crone, Panagiotis Koutakis, Jeff S. Forsse

International Journal of Exercise Science: Conference Proceedings

Maximal oxygen uptake (VO2 Max) is utilized to assess cardiorespiratory fitness (CRF) and performance in various populations. Although VO2max is the gold standard for assessing aerobic performance and CRF, the accessibility, time, and cost are limiting factors for frequent evaluation. Recently, skeletal muscle oxygen saturation (SmO2) has been utilized to characterize the amount of oxygen available in skeletal muscle tissue and the efficiency of oxygen uptake and to serve as an alternative metric to assess CRF. However, minimal research has been conducted to observe the difference in SmO2 location placement between the vastus laterals (VL) and gastrocnemius (GS) during exhaustive …

The Transient Influence Of Acute Bouts Of Aerobic Exercise On Vitamind Concentrations In Moderate Stages Of Chronic Kidney Disease, Meena Meiyyappan, Leroy Bolden, Tomas Chapman-Lopez, Ricardo Torres, James K. Taylor, Keri Collins, Crawford Allison, Panagiotis Koutakis, Jeff S. Forsse

International Journal of Exercise Science: Conference Proceedings

Chronic kidney disease (CKD) is a gradual loss of renal filtration and has been shown to be associated with lower levels of vitamin D (Vit-D). Vit-D is highly synthesized in the kidneys and is linked to multiple health conditions. Aerobic exercise of differing intensity and modality has shown potential in acutely improving Vit-D concentration in healthy and diseased populations. Purpose: To determine the influence of acute bouts of high-intensity interval exercise (HIIE) and steady-state exercise (SSE) on Vit-D concentrations in individuals with moderate stages of CKD. Methods: A total of 13 participants (n = 7 women; n = 6 men; …

The Influence Of High-Intensity Interval Exercise On Vitamin-D Concentrations In Healthy Individuals, Leroy K. Bolden, Tomas Chapman-Lopez, Ricardo Torres, Jeffery Heileson, Meena Meiyyappan, Jeff S. Forsse

International Journal of Exercise Science: Conference Proceedings

Vitamin D (VD) deficiency is one of the most common deficiencies in the world due to various factors (e.g., lack of sun exposure, dietary considerations). Currently the utilization of exercise may act as an intervention for VD deficiencies to promote increases in VD concentrations in healthy populations. This could largely be due to the loss of calcium from aerobic exercise (AE), leading to a hormonal response [(e.g., parathyroid hormone (PTH)] and the activation of cytochrome’s (e.g., CYP2R1, CYP27B1) responsible for the regulation of VD. Thus, AE may serve as an intervention to promote VD synthesis due to the impacted biological …

Vitamin D3 Supplementation Alters Gut Microbiome Composition And Increases Stability In Healthy Individuals, Madhur Wyatt, Ankan Choudhury, Gabriella Von Dohlen, Jeffery L. Heileson, Jeff S. Forsse, Leigh Greathouse

International Journal of Exercise Science: Conference Proceedings

Early onset colorectal cancer incidence has increased significantly. Evidence links serum 25(OH)D levels and the gut microbiome to colon carcinogenesis, with vitamin D pivotal in modulating the immune system and intestinal epithelial function. The effect of supplemental vitamin D₃ on the gut microbiome in healthy adults is unclear. PURPOSE: Investigate the effect of a 12-week oral dose of 4000 IU vitamin D₃ on acute and long-term gut microbiome changes in healthy adults. METHODS: Forty-three participants, aged 18-53, were randomized based on baseline serum 25(OH)D levels into treatment (n=21) and placebo groups (n=22). Fecal samples …

Technical And Biological Error Of Skeletal Muscle Mass Estimation From Dual-Energy X-Ray Absorptiometry, Christian Rodriguez, Madelin R. Siedler, Christine M. Florez, Grant M. Tinsley

International Journal of Exercise Science: Conference Proceedings

The increasing prevalence of conditions like sarcopenia, sarcopenic obesity, frailty, and cachexia emphasizes the need for reliable methods to estimate skeletal muscle mass (SMM). Data obtained from dual-energy X-ray absorptiometry (DXA) can be used within prediction equations to estimate whole-body SMM. However, limited data are available to inform the reliability of SMM estimates from prediction equations. PURPOSE: The purpose of this study was to determine the technical and biological error of SMM estimation across two DXA devices. METHODS: A sample of 18 generally healthy adults (11 F, 7 M; [mean ± SD] age 24.4 ± 8.7 y, body mass index …

Shed Stem Cells: Antibacterial And Immunomodulatory Insights, Manju R Prof

Annual Research Symposium

SHED- Stem cells extracted from exfoliated teeth - resource for Stem Cell based regenerative therapy; multipotent in nature

We examined explored how SHED affects the growth of common oral bacteria, Streptococcus mutans and Enterococcus faecalis, and their role in regulating immune response.

Biological Stimulants Increase Fertilizer Efficiency And Pasture Legume Content, P. R. Espie, S. Haswell, A. Barton

IGC Proceedings (1977-2023)

The effects of a soil biological stimulant (SS) and biologically activated reactive phosphate rock (BAP) on pasture yield and botanical composition were examined in a field trial in low-fertility New Zealand rangeland. BAP application significantly increased pasture yield by 60% and BAP plus biostimulant increased yield by 120%. BAP significantly increased resident legume cover by 75% and BAP with biostimulants by 85%. Alfalfa, direct drilled as an indicator test species, increased in establishment from 0 to 3.8 plants m-2 with BAP and to 4.2 plants m-2 with BAP plus biostimulant. Biostimulant applied alone increased yield by 17%, legume cover by …

Uf-Accelerate To Industry (A2i): Bringing Industry Into Academia, J. A. Estrada

IGC Proceedings (1977-2023)

University stakeholders are targeting candidates with competency in a wide range of professional skills, including team building and leadership, multi-modal communication, intercultural awareness, emotional intelligence, and mental flexibility. We developed UF-Accelerate to Industry (A2i) to deliver these skills to our graduate students and better prepare them to enter a competitive, rapidly evolving workforce. UF-A2i is delivered as day-long “immersion” events, consisting of presentations, panel discussions, skills workshops, and group projects. All activities are led by industry sponsors or career preparation specialists and are focused on building industry-identified skills that will give attendees a competitive edge in the job market. Since …

The Use Of Livestock Gps Trackers To Determine The Grazing Patterns Of Herded And Free Ranging Cattle In The Communal Rangelands Of The Eastern Cape Province, South Africa, A. Finca, T. C. Zondani, J. T. Tjelele, M. P. Mavuso

IGC Proceedings (1977-2023)

This study was set in the Eastern Cape Province of South Africa which is predominantly rural and where livelihood sustainability is largely dependent on agricultural outputs including livestock production. Land in many of the rural, former homeland areas is held under communal land tenure which means access, utilisation and management is on a collective basis. A number of grazing strategies have been applied over the last hundred years including camp rotational grazing system. However, due to a number of factors including the absence of the communal rangeland and camp boundary fence, most villages do not have a rangeland management strategy …

Preparing Grasslands Scientists For Careers In International Agriculture, M. Eilittä

IGC Proceedings (1977-2023)

Livelihoods of a billion poor people depend on grasslands. Dedicated and trained experts are needed to support grasslands’ sustainable development under increasing pressures in the future. For some grasslands scientists, a career in international agriculture is the principal focus from the start of their education. For others, interest in international agriculture emerges during their careers. All require international opportunities to ensure that their efforts are focused on important priorities, that they understand the environment they work in, and that their professional networks are up to date. This paper reflects on ways for grassland scientists to be engaged in international agriculture …

How ‘Pasture For Life (Championing 100% Pasture-Fed Ruminant Products) Has Taken Off In The Uk – From The Bottom Up!, S. J. Gregson

IGC Proceedings (1977-2023)

Ten years ago Pasture for Life (PfL) was a collection of around 50 UK farmers who were producing high quality ruminant food products wholly from pasture. They were regenerative farming pioneers and PfL was run by volunteers and funded through various grants. In the past two to three years, membership has increased significantly, nearing 1,000 with almost 150 certified Pasture for Life (100% grass-fed). The organisation is now run by a paid executive and is bursting with energy, conversation, and learning. Members are mainly farmers, but also include butchers, chefs, vets, academics and consumers – all keen to champion the …

Rotational Stocking With Virtual Fences: Effects On Grassland Diet Digestibility, Livestock Performance And Stress Levels Of Heifers, N. A. Grinnell, D. Hamidi, M. Komainda, F. Reisch, J. Horn, I. Traulsen, R. Palme, J. Isselstein

IGC Proceedings (1977-2023)

Virtual fencing is an innovative technology for simplified, less laborious dynamic grazing management and remote animal monitoring. The effect of this novel technology on animal welfare is still a matter of debate. Previous research suggests no differences in stress experience responses of cattle between the two fencing systems on continuously stocked pastures. This study investigated differences in diet organic matter digestibility, livestock performance and fecal cortisol metabolite concentrations of heifers on pastures in a rotational grazing system, fenced with a virtual fence (Nofence, Batnfjordsøra Norway) compared to heifers fenced with a traditional electric wire fence. The study was conducted in …

Non-Hodgkin's Lymphoma Of The Oral Cavity - A Rare Entity, Anita J. Florence Dr, Karpagaselvi Sanjai Prof & Dr

Annual Research Symposium

Non-Hodgkin’s lymphoma (NHL) is a subtype of lymphoma with two-thirds of the cases presenting as lymph node enlargement. The remaining one third of NHL cases has been reported in the extra nodal sites, including the gastro-intestinal tract, Waldeyer’s ring, bone, skin and brain. Intraoral NHL is uncommon and may affect either the jaw bones or occur within the soft tissues of the oral cavity. Here we report an unusual case of non-Hodgkin’s lymphoma in a 54-year-old male patient who presented with a growth from the right lower molar extraction socket with pus discharge.

New Onset Positive Autoantibodies Following Covid-19 Infection, David Hernandez, Adnaan Sheikh, Shakira Laing, Mariana Adieb, Omar Siddiqui, Rohail Baig, Annabel Antonini, James Vienneau, Camden Burns

Advances in Clinical Medical Research and Healthcare Delivery

The World Health Organization (WHO) declared the novel coronavirus (COVID-19) outbreak a global pandemic on March 11, 2020. Since the original outbreak in December 2019, over 100 million people have been confirmed to have been infected by COVID-19 and over two million people have died. The presentation seen in patients may vary widely based on multiple factors. Fever has been reported in up to 99% of patients, while other common symptoms seen are dyspnea, fatigue, anosmia, and myalgia. Around 80% of COVID-19 patients present with a mild respiratory illness that can be managed at home, while around 15% need basic …

Radio-Histopathological Presentation And Multidisciplinary Treatment Of Adolescent Paratesticular Rhabdomyosarcoma: A Case Report, Troy Nguyen, Joseph Hatem, Abhijit Datir, Joel Thompson

Advances in Clinical Medical Research and Healthcare Delivery

Paratesticular rhabdomyosarcoma (PRMS) is a rare condition predominantly affecting the pediatric and adolescent population. In this case report, we discuss a 17-year-old male with a slow-growing, painless scrotal mass, ultimately diagnosed as embryonal PRMS — the most common and favorable rhabdomyosarcoma subtype. The report underscores the typical clinico-radiological presentation of PRMS and the pivotal part of histopathological evaluation in establishing a definitive diagnosis. Multidisciplinary intervention including surgery and chemoradiotherapy resulted in total remission. Therefore, this report underlines the significance of prompt diagnosis and comprehensive management in ensuring a favorable prognosis of PRMS.

Orthodontic And Surgical Treatment Of A Patient With Cleidocranial Dysplasia Syndrome: Introducing A New Appliance For Traction Of Multiple Impacted Teeth, Sanaz Soheilifar, Sepideh Soheilifar, Sara Soheilifar, Navid Naghdi

Taiwanese Journal of Orthodontics

Cleidocranial Dysplasia (CCD) is a syndrome that causes skeletal growth disturbances. The impaction of many permanent teeth and several supernumerary teeth are among the dental problems of patients with this syndrome. This patient was a 14 y/o girl with CCD syndrome. She was skeletal Cl III with reverse overjet; many impacted teeth, and several supernumerary teeth. Orthodontic treatment was done in two stages. In the first stage, supernumerary anterior teeth were extracted, and the impacted teeth were exposed for traction. In the second stage, posterior supernumerary teeth were removed, and upper canines and posterior impacted teeth were exposed for forced …

How Can You Tell If There Is A Crisis? Data And Measurement Challenges In Assessing Jury Representation, Mary R. Rose, Marc A. Musick

Chicago-Kent Law Review

No abstract provided.

Eight Students Win Gardner-Webb’S Ignite Excellence Full-Tuition Scholarship, Office Of University Communications, Isabella Brown

Gardner-Webb NewsCenter Archive

The winners of Gardner-Webb University’s most competitive academic scholarship—Ignite Excellence—have been announced. These eight high school seniors rose above the 288 top-ranked students who came from 19 states to participate in on-campus interviews.

Ksu University Band & University Philharmonic Orchestra

Bailey School of Music Concert Programs

Program for the KSU University Band & University Philharmonic Orchestra performance on February 20, 2024.

Perceptions Of Financial Exploitation Among Older African American Women In The Black Church, Patricia Jackson

Walden Dissertations and Doctoral Studies

Perceptions of Financial Exploitation Among Older African American Women in the Black Church by Patricia Jackson MS, Walden University, 2016 BA, Langston University, 1977 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Social and Behavioral Sciences, Family Studies and Intervention Walden University February 2024