Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 79501 - 79530 of 818756

Full-Text Articles in Entire DC Network

Effects Of Urbanization On Dissolved Carbon And Nutrients In The Johnson Creek Watershed On Long-Term Temporal Scales, Jacob Rudolph, Jennifer L. Morse, Rebecca L. Hale Mar 2024

Effects Of Urbanization On Dissolved Carbon And Nutrients In The Johnson Creek Watershed On Long-Term Temporal Scales, Jacob Rudolph, Jennifer L. Morse, Rebecca L. Hale

Urban Ecosystem Research Consortium of Portland/Vancouver

Dissolved organic carbon (DOC), the largest flux of carbon in streams, is a vital metric in urban stream ecology that is often overlooked, especially on seasonal scales. Microorganisms metabolize DOC, which can decrease dissolved oxygen and pH and harm other aquatic species. Johnson Creek watershed, located in the Portland metro area, provides an ideal location to study the effect of urbanization on DOC and water quality resulting from channelization and urban land. We hypothesize that DOC will increase downstream as impervious surface cover and urbanization increase. To quantify DOC concentration temporal changes, surface water samples were collected weekly from three …


Why Is The Oaks Bottom Reservoir So Dead And Brown? A Success Story Of Purple Loosestrife Control, Laura Guderyahn Mar 2024

Why Is The Oaks Bottom Reservoir So Dead And Brown? A Success Story Of Purple Loosestrife Control, Laura Guderyahn

Urban Ecosystem Research Consortium of Portland/Vancouver

Ever since the early 1990’s, when a water control structure was used to flood the 60acre ponded wetland at Oaks Bottom to increase waterfowl overwintering habitat, Purple Loosestrife (Lythrum salicaria) has thrived. Starting in 2008, Portland Parks and Recreation (PPR) and the Bureau of Environmental Services (BES) partnered with the Oregon Department of Agriculture (ODA) to annually release thousands of three different species of biocontrol beetles throughout the wetland. However, the unnatural flooding regime due to the water control structure and a greatly undersized culvert connecting the refuge to the Willamette River, resulted in annual reproductive and overwintering …


Proceedings Of The 22nd Annual Urban Ecology & Conservation Symposium (2024), Lori Hennings Mar 2024

Proceedings Of The 22nd Annual Urban Ecology & Conservation Symposium (2024), Lori Hennings

Urban Ecosystem Research Consortium of Portland/Vancouver

These proceedings document the agenda and abstracts for presentations and posters from the 22nd annual conference (2024) organized by the Urban Ecosystem Research Consortium of Portland/Vancouver (UERC). The UERC is a consortium of people from various universities and colleges, state and federal agencies, local governments, non-profit organizations and independent professionals interested in supporting urban ecosystem research and creating an information-sharing network of people that collect and use ecological data in the Portland/Vancouver area. The annual conference has an open call for abstracts. The UERC organizing committee selects the final oral and poster presentations, along with 2 invited keynote presentations


Up-Regulation Of Non-Photochemical Quenching Improves Water Use Efficiency And Reduces Whole-Plant Water Consumption Under Drought In Nicotiana Tabacum, Benjamin Turc, Seema Sahay, Jared Haupt, Talles De Oliveira Santos, Geng Bai, Katarzyna Glowacka Mar 2024

Up-Regulation Of Non-Photochemical Quenching Improves Water Use Efficiency And Reduces Whole-Plant Water Consumption Under Drought In Nicotiana Tabacum, Benjamin Turc, Seema Sahay, Jared Haupt, Talles De Oliveira Santos, Geng Bai, Katarzyna Glowacka

Center for Plant Science Innovation: Faculty Publications

Water supply limitations will likely impose increasing restrictions on future crop production, underlining a need for crops that use less water per mass of yield. Water use efficiency (WUE) therefore becomes a key consideration in developing resilient and productive crops. In this study, we hypothesized that it is possible to improve WUE under drought conditions via modulation of chloroplast signals for stomatal opening by up-regulation of non-photochemical quenching (NPQ). Nicotiana tabacum plants with strong overexpression of the PsbS gene encoding PHOTOSYSTEM II SUBUNIT S, a key protein in NPQ, were grown under differing levels of drought. The PsbS-overexpressing lines lost …


Lanthorn, Vol. 58, No. 14, March 11, 2024, Grand Valley State University Mar 2024

Lanthorn, Vol. 58, No. 14, March 11, 2024, Grand Valley State University

Volume 58, August 7, 2023 - April 15, 2024

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.


How To Identify Various Sparrow Species, Aidan Castricone '24, Alexis Larsen '24, Emma Barry '25 Mar 2024

How To Identify Various Sparrow Species, Aidan Castricone '24, Alexis Larsen '24, Emma Barry '25

Biology Student Scholarship

A helpful infographic on how to differentiate between four little brown birds: the house sparrow, the song sparrow, the white-throated sparrow, and the swamp sparrow. Animal behavior (BIO 350/350L) final project


Seven Behaviors Exhibited In The Blue Jay, Gillian Chapleau '24, Jide Owoeye '23 Mar 2024

Seven Behaviors Exhibited In The Blue Jay, Gillian Chapleau '24, Jide Owoeye '23

Biology Student Scholarship

A quick guide to understanding common behaviors exhibited by blue jays. Animal behavior (BIO 350/350L) final project


Black Social Workers Use Of Racial Identity And Self Concept In The Workplace, Shielah Monique Deblanc Mar 2024

Black Social Workers Use Of Racial Identity And Self Concept In The Workplace, Shielah Monique Deblanc

Walden Dissertations and Doctoral Studies

Navigating the Black professional identity in U.S. work environments poses challenges for social workers, with limited research addressing racial salience, power dynamics, and self-concept within their specific workplace contexts. Using self-concept theory, and the multidimensional model of racial identity as theoretical and conceptual frameworks, the purpose of this research was to examine Black social workers’ attitudes about self-concept using racial salience, power distance, and employee tenure as predictors. Using web-based surveys to collect data, a purposive sample of 77 participants were used to complete demographic information, a measure of centrality to gauge racial salience Multidimensional Inventory of Black Identity, a …


Blue Jays, Meriam Salo '25, Gabriela Guzman Reyes '24 Mar 2024

Blue Jays, Meriam Salo '25, Gabriela Guzman Reyes '24

Biology Student Scholarship

A guide to identifying blue jays, and understanding their common behaviors. Animal behavior (BIO 350/350L) final project


Role Of Glia In Diurnal Rhythms In Neuroinflammation And Blood-Brain Barrier Breakdown, Jennifer Hoi-Ping Lawrence Mar 2024

Role Of Glia In Diurnal Rhythms In Neuroinflammation And Blood-Brain Barrier Breakdown, Jennifer Hoi-Ping Lawrence

Arts & Sciences Graduate Student Theses and Dissertations

While inflammation is an important mechanism for the return to homeostasis post insult or injury, inflammation in the central nervous system (CNS) can lead to irreparable damage. To mitigate this process, the brain is protected from circulating neurotoxic molecules as well as peripheral immune cells through the tightly regulated blood-brain barrier (BBB). The balance between pro- and anti- inflammation in the CNS rapidly shifts towards a neurotoxic proinflammatory state during acute bacterial or viral infections or chronic neuroinflammatory diseases. Excessive inflammatory responses are also coupled with extensive BBB leakage and breakdown, allowing rampant entry of peripheral inflammatory cells and mediators …


Exploring Practices Of Board-Certified Pediatric Clinical Specialst Physical Therapists In Addressing Needs Of Children Diagnosed With Autism Spectrum Disorder, Olga Chaikovsky Mar 2024

Exploring Practices Of Board-Certified Pediatric Clinical Specialst Physical Therapists In Addressing Needs Of Children Diagnosed With Autism Spectrum Disorder, Olga Chaikovsky

Seton Hall University Dissertations and Theses (ETDs)

ABSTRACT

Background: Autism spectrum disorder (ASD) is a complex condition affecting multiple domains of development. Physical Therapists (PTs) are members of the interprofessional team addressing the needs of individuals with ASD. A lack of uniformity in evidence-based assessments and practices employed by therapists to address the needs of children with ASD exists in the literature. PTs often implement approaches that are not evidence-based but rather learned from more experienced professionals or discovered by trial and error.

Pediatric clinical specialist physical therapists (PCSPTs) are PTs who possess advanced education and clinical skills in Pediatrics. As pediatric experts, PCSPTs play a major …


Mallards And Their Interesting Facts, Caitlin Mchugh '24, Jessica Slaton '24 Mar 2024

Mallards And Their Interesting Facts, Caitlin Mchugh '24, Jessica Slaton '24

Biology Student Scholarship

A guide on how to differentiate between male and female mallards, where to find these ducks, and their common behaviors. Animal behavior (BIO 350/350L) final project


Identifying The American Goldfinch, Margaret Low '24, Laura Mooney '24 Mar 2024

Identifying The American Goldfinch, Margaret Low '24, Laura Mooney '24

Biology Student Scholarship

An infographic with tips on how to identify a common backyard visitor, the American goldfinch. Animal behavior (BIO 350/350L) final project


Messages From The Provost, Georgia Southern University Mar 2024

Messages From The Provost, Georgia Southern University

Messages from the Provost

Excellence in Action

Emerging Scholar

CPE: Free Community Programs

Good News

Congratulations Corner


Characterizing Multimorbidity Prevalence And Adverse Outcomes In Ethnically And Culturally Diverse Sub-Populations In India: Gaps, Opportunities, And Future Directions, Preeti Zanwar, Robyn Taylor, Tanisha Hill-Jarrett, Elena Tsoy, Jason Flatt, Zunera Mirza, Carl Hill, Arokiasamy Perianayagam Mar 2024

Characterizing Multimorbidity Prevalence And Adverse Outcomes In Ethnically And Culturally Diverse Sub-Populations In India: Gaps, Opportunities, And Future Directions, Preeti Zanwar, Robyn Taylor, Tanisha Hill-Jarrett, Elena Tsoy, Jason Flatt, Zunera Mirza, Carl Hill, Arokiasamy Perianayagam

College of Population Health Faculty Papers

India is a large middle-income country and has surpassed China in overall population, comprising 20% of the global population (over 1.43 billion people). India is experiencing a major demographic shift in its aging population. Chronic diseases are common among older adults and can be persistent over the life course, lead to the onset of disability, and be costly. Among older adults in India, the existence of multiple comorbid chronic conditions (i.e., multimorbidity) is rapidly growing and represents a burgeoning public health burden. Prior research identified greater rates of multimorbidity (e.g., overweight/obesity diabetes, hypertension, cardiovascular disease, stroke, and malignancies) in minority …


Automating Data Analysis For Hydrogen/Deuterium Exchange Mass Spectrometry Using Data-Independent Acquisition Methodology, Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D Alex Crowder, Morgan F Khan, Pauline Douglas, Stephen Coales, Rosa Viner, Aleem Syed, John A Tainer, Susan P Lees-Miller, David C Schriemer Mar 2024

Automating Data Analysis For Hydrogen/Deuterium Exchange Mass Spectrometry Using Data-Independent Acquisition Methodology, Frantisek Filandr, Vladimir Sarpe, Shaunak Raval, D Alex Crowder, Morgan F Khan, Pauline Douglas, Stephen Coales, Rosa Viner, Aleem Syed, John A Tainer, Susan P Lees-Miller, David C Schriemer

Faculty, Staff and Student Publications

We present a hydrogen/deuterium exchange workflow coupled to tandem mass spectrometry (HX-MS2) that supports the acquisition of peptide fragment ions alongside their peptide precursors. The approach enables true auto-curation of HX data by mining a rich set of deuterated fragments, generated by collisional-induced dissociation (CID), to simultaneously confirm the peptide ID and authenticate MS1-based deuteration calculations. The high redundancy provided by the fragments supports a confidence assessment of deuterium calculations using a combinatorial strategy. The approach requires data-independent acquisition (DIA) methods that are available on most MS platforms, making the switch to HX-MS2 straightforward. Importantly, we find that HX-DIA enables …


Comparing Task Graph Scheduling Algorithms: An Adversarial Approach, Jared Coleman, Bhaskar Krishnamachari Mar 2024

Comparing Task Graph Scheduling Algorithms: An Adversarial Approach, Jared Coleman, Bhaskar Krishnamachari

Computer Science Faculty Works

Scheduling a task graph representing an application over a heterogeneous network of computers is a fundamental problem in distributed computing. It is known to be not only NP-hard but also not polynomial-time approximable within a constant factor. As a result, many heuristic algorithms have been proposed over the past few decades. Yet it remains largely unclear how these algorithms compare to each other in terms of the quality of schedules they produce. We identify gaps in the traditional benchmarking approach to comparing task scheduling algorithms and propose a simulated annealing-based adversarial analysis approach called PISA to help address them. We …


Characterizing Multimorbidity Prevalence And Adverse Outcomes In Ethnically And Culturally Diverse Sub-Populations In India: Gaps, Opportunities, And Future Directions, Preeti P. Zanwar, Robyn Taylor, Tanisha G. Hill-Jarrett, Elena Tsoy, Jason D. Flatt, Zunera Mirza, Carl V. Hill, Arokiasamy Perianayagam Mar 2024

Characterizing Multimorbidity Prevalence And Adverse Outcomes In Ethnically And Culturally Diverse Sub-Populations In India: Gaps, Opportunities, And Future Directions, Preeti P. Zanwar, Robyn Taylor, Tanisha G. Hill-Jarrett, Elena Tsoy, Jason D. Flatt, Zunera Mirza, Carl V. Hill, Arokiasamy Perianayagam

Pacific Faculty Work

India is a large middle-income country and has surpassed China in overall population, comprising 20% of the global population (over 1.43 billion people). India is experiencing a major demographic shift in its aging population. Chronic diseases are common among older adults and can be persistent over the life course, lead to the onset of disability, and be costly. Among older adults in India, the existence of multiple comorbid chronic conditions (i.e., multimorbidity) is rapidly growing and represents a burgeoning public health burden. Prior research identified greater rates of multimorbidity (e.g., overweight/obesity diabetes, hypertension, cardiovascular disease, stroke, and malignancies) in minority …


Public Health Insurance: An Approach To Mitigate The Burden Of Diabetes In Low Resource Settings, Jideuma I. Egwim, Namgyal Kyulo, Hadi Danawi, Aaron B. Mendelsohn Mar 2024

Public Health Insurance: An Approach To Mitigate The Burden Of Diabetes In Low Resource Settings, Jideuma I. Egwim, Namgyal Kyulo, Hadi Danawi, Aaron B. Mendelsohn

Journal of Social, Behavioral, and Health Sciences

Background: Diabetes mellitus is a significant public health concern globally as well as in Owerri, Nigeria. The deleterious effects of diabetes have been linked to poor glycemic control. According to the International Diabetes Federation, poor glycemic control is reflected in glycosylated hemoglobin levels greater than 7.0%, which are associated with substantial morbidity and mortality. Studies have shown a dramatic rise in diabetic complications in Nigeria, particularly in Owerri. However, evidence is lacking on specific risk factors associated with poor glycemic control among diabetes mellitus patients in Owerri. There is a gap in the literature regarding the association between health insurance …


Mir-200c Reprograms Fibroblasts To Recapitulate The Phenotype Of Cafs In Breast Cancer Progression, Zhao Lin, Megan Roche, Víctor Díaz-Barros, Marina Domingo-Vidal, Diana Menezes, Madalina Tuluc, Guldeep Uppal, Jaime Caro, Joseph Curry, Ubaldo Martinez-Outshoorn Mar 2024

Mir-200c Reprograms Fibroblasts To Recapitulate The Phenotype Of Cafs In Breast Cancer Progression, Zhao Lin, Megan Roche, Víctor Díaz-Barros, Marina Domingo-Vidal, Diana Menezes, Madalina Tuluc, Guldeep Uppal, Jaime Caro, Joseph Curry, Ubaldo Martinez-Outshoorn

Kimmel Cancer Center Faculty Papers

Mesenchymal-epithelial plasticity driving cancer progression in cancer-associated fibroblasts (CAFs) is undetermined. This work identifies a subgroup of CAFs in human breast cancer exhibiting mesenchymal-to-epithelial transition (MET) or epithelial-like profile with high miR-200c expression. MiR-200c overexpression in fibroblasts is sufficient to drive breast cancer aggressiveness. Oxidative stress in the tumor microenvironment induces miR-200c by DNA demethylation. Proteomics, RNA-seq and functional analyses reveal that miR-200c is a novel positive regulator of NFκB-HIF signaling via COMMD1 downregulation and stimulates pro-tumorigenic inflammation and glycolysis. Reprogramming fibroblasts toward MET via miR-200c reduces stemness and induces a senescent phenotype. This pro-tumorigenic profile in CAFs fosters carcinoma …


The Experience Of Correctional Officers Who Have Witnessed Inmate Suicide, Amanda Michelle Burrell Mar 2024

The Experience Of Correctional Officers Who Have Witnessed Inmate Suicide, Amanda Michelle Burrell

Walden Dissertations and Doctoral Studies

Correctional officers are tasked with supervising individuals in custody. Their duties are plentiful and include responding to critical incidents, such as inmate suicide. The purpose of this generic qualitative study was to explore the experience of correctional officers in the United States who have witnessed inmate suicide. Lazarus and Folkman’s transactional model of stress and coping was used to guide this study. Participants included eight correctional officers within the United States who have witnessed inmate suicide. These participants were selected using purposive and snowball sampling. Virtual, semi-structured, audio recorded interviews were conducted with participants. Data were analyzed using Braun and …


Dissolved Nickel Speciation At The Bermuda Atlantic Time-Series Study (Bats) Site, Caitlyn E. Parente Mar 2024

Dissolved Nickel Speciation At The Bermuda Atlantic Time-Series Study (Bats) Site, Caitlyn E. Parente

USF Tampa Graduate Theses and Dissertations

Here I present the first depth profiles of dissolved nickel (DNi) speciation over an annual cycle at the Bermuda Atlantic Time-series Study (BATS) site in the North Atlantic. Seawater samples were collected in March, May, August, and November 2019 and analyzed for labile DNi using competitive ligand exchange-adsorptive cathodic stripping voltammetry (CLE-AdCSV). Labile DNi was measured by CLE-AdCSV as the fraction of DNi that exchanges with an added competitive ligand in an overnight equilibration. Results revealed two distinct fractions of DNi present throughout the water column: a labile fraction, and a strongly organically complexed (i.e., non-labile) fraction. More than 50% …


Metabolomic Profiles In Jamaican Children With And Without Autism Spectrum Disorder, Akram Yazdani, Maureen Samms-Vaughan, Sepideh Saroukhani, Jan Bressler, Manouchehr Hessabi, Amirali Tahanan, Megan L Grove, Tanja Gangnus, Vasanta Putluri, Abu Hena Mostafa Kamal, Nagireddy Putluri, Katherine A Loveland, Mohammad H Rahbar Mar 2024

Metabolomic Profiles In Jamaican Children With And Without Autism Spectrum Disorder, Akram Yazdani, Maureen Samms-Vaughan, Sepideh Saroukhani, Jan Bressler, Manouchehr Hessabi, Amirali Tahanan, Megan L Grove, Tanja Gangnus, Vasanta Putluri, Abu Hena Mostafa Kamal, Nagireddy Putluri, Katherine A Loveland, Mohammad H Rahbar

Faculty, Staff and Student Publications

BACKGROUND: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a wide range of behavioral and cognitive impairments. While genetic and environmental factors are known to contribute to its etiology, the underlying metabolic perturbations associated with ASD which can potentially connect genetic and environmental factors, remain poorly understood. Therefore, we conducted a metabolomic case-control study and performed a comprehensive analysis to identify significant alterations in metabolite profiles between children with ASD and typically developing (TD) controls.

OBJECTIVE: To elucidate potential metabolomic signatures associated with ASD in children and identify specific metabolites that may serve as biomarkers for the disorder. …


Nanofibrous Multidomain Peptide Hydrogels Provide T Cells A 3d, Cytocompatible Environment For Cell Expansion And Antigen-Specific Killing, Viridiana Leyva-Aranda, Shailbala Singh, Maria J Telesforo, Simon Young, Cassian Yee, Jeffrey D Hartgerink Mar 2024

Nanofibrous Multidomain Peptide Hydrogels Provide T Cells A 3d, Cytocompatible Environment For Cell Expansion And Antigen-Specific Killing, Viridiana Leyva-Aranda, Shailbala Singh, Maria J Telesforo, Simon Young, Cassian Yee, Jeffrey D Hartgerink

Faculty, Staff and Student Publications

T cells have the ability to recognize and kill specific target cells, giving therapies based on their potential for treating infection, diabetes, cancer, and other diseases. However, the advancement of T cell-based treatments has been hindered by difficulties in their ex vivo activation and expansion, the number of cells required for sustained in vivo levels, and preferential localization following systemic delivery. Biomaterials may help to overcome many of these challenges by providing a combined means of proliferation, antigen presentation, and cell localization upon delivery. In this work, we studied self-assembling Multidomain Peptides (MDPs) as scaffolds for T cell culture, activation, …


Ape-Gen20: Expanding Rapid Class I Peptide-Major Histocompatibility Complex Modeling To Post-Translational Modifications And Noncanonical Peptide Geometries, Romanos Fasoulis, Mauricio M Rigo, Gregory Lizée, Dinler A Antunes, Lydia E Kavraki Mar 2024

Ape-Gen20: Expanding Rapid Class I Peptide-Major Histocompatibility Complex Modeling To Post-Translational Modifications And Noncanonical Peptide Geometries, Romanos Fasoulis, Mauricio M Rigo, Gregory Lizée, Dinler A Antunes, Lydia E Kavraki

Faculty, Staff and Student Publications

The recognition of peptides bound to class I major histocompatibility complex (MHC-I) receptors by T-cell receptors (TCRs) is a determinant of triggering the adaptive immune response. While the exact molecular features that drive the TCR recognition are still unknown, studies have suggested that the geometry of the joint peptide–MHC (pMHC) structure plays an important role. As such, there is a definite need for methods and tools that accurately predict the structure of the peptide bound to the MHC-I receptor. In the past few years, many pMHC structural modeling tools have emerged that provide high-quality modeled structures in the general case. …


Intouch Week Of March 11, 2024, New York Medical College Mar 2024

Examining The Impact Of Stream Permanence On Headwater Stream Carbon Emissions, Hannah D. Conroy, Erin R. Hotchkiss, Kaelin M. Cawley, Keli Goodman, Jeremy B. Jones, Wilfred M. Wollheim, David Butman Mar 2024

Examining The Impact Of Stream Permanence On Headwater Stream Carbon Emissions, Hannah D. Conroy, Erin R. Hotchkiss, Kaelin M. Cawley, Keli Goodman, Jeremy B. Jones, Wilfred M. Wollheim, David Butman

Faculty Publications

Quantifying headwater stream carbon emissions is important for our understanding of the global carbon cycle because these emissions (an estimated 0.93-1.15 Pg C year) can be substantial compared to the terrestrial flux. Headwater stream networks can have high emissions due to their coupling with the terrestrial environment and high turbulence with some estimates predicting headwater stream networks can contribute 70% of the global riverine stream emissions. These carbon emissions are challenging to predict, especially with regards to headwater stream network spatiotemporal heterogeneity. The majority of headwater streams exhibit changes in stream network area on a seasonal basis, and these locations …


Racial And Socioeconomic Disparities In Survival Improvement Of Eight Cancers, Vikram Shaw, Baoyi Zhang, Mabel Tang, William Peng, Christopher Amos, Chao Cheng Mar 2024

Racial And Socioeconomic Disparities In Survival Improvement Of Eight Cancers, Vikram Shaw, Baoyi Zhang, Mabel Tang, William Peng, Christopher Amos, Chao Cheng

Faculty, Staff and Students Publications

BACKGROUND: Many studies have characterized racial differences in cancer outcomes, demonstrating that black and Hispanic patients have lower cancer-specific survival compared to white patients. However, to our knowledge, a gap in the literature exists regarding racial, socioeconomic, age, and sex-related differences in survival improvement in cancer.

METHODS: We perform a population-based cohort study of 1,875,281 patients with eight common cancer sites from the Surveillance, Epidemiology, and End Results (SEER) database.

RESULTS: The longitudinal data demonstrates that while overall cancer-free survival has improved from 2004 to 2018, certain groups have seen lower rates of improvement. Black patients have the lowest cancer-specific …


Dyspnea (Breathlessness) In Amyotrophic Lateral Sclerosis/Motor Neuron Disease: Prevalence, Progression, Severity, And Correlates, Carolyn A. Young, Amina Chaouch, Christopher J. Mcdermott, Ammar Al-Chalabi, Suresh K. Chhetri, Kevin Talbot, Timothy Harrower, Richard W. Orrell, Joe Annadale, Oliver C. Hanemann, Antonio Scalfari, Alan Tennant, Roger Mills Mar 2024

Dyspnea (Breathlessness) In Amyotrophic Lateral Sclerosis/Motor Neuron Disease: Prevalence, Progression, Severity, And Correlates, Carolyn A. Young, Amina Chaouch, Christopher J. Mcdermott, Ammar Al-Chalabi, Suresh K. Chhetri, Kevin Talbot, Timothy Harrower, Richard W. Orrell, Joe Annadale, Oliver C. Hanemann, Antonio Scalfari, Alan Tennant, Roger Mills

Peninsula Medical School

Objective: Dyspnea, or breathlessness, is an important symptom in amyotrophic lateral sclerosis/motor neuron disease (ALS/MND). We examined the measurement properties of the Dyspnea-12. Methods: Rasch analysis enabled conversion of raw Dyspnea-12 scores to interval level metric equivalents. Converted data were used to perform trajectory modeling; those following different trajectories were compared for demographic, clinical, symptom, and functioning characteristics. Logistic regression examined differences between distinct trajectories. Results: In 1022 people, at baseline, mean metric Dyspnea-12 was 7.6 (SD 9.3). 49.8% had dyspnea, severe in 12.6%. Trajectory analysis over 28 months revealed three breathlessness trajectories: group 1 reported none at baseline/follow-up (42.7%); …


The Role Of Internal And External Factors In The Grand Ethiopian Renaissance Dam (Gerd) Crisis, Mariam Hassan, Mohamed Nour Al-Bosrati Mar 2024

The Role Of Internal And External Factors In The Grand Ethiopian Renaissance Dam (Gerd) Crisis, Mariam Hassan, Mohamed Nour Al-Bosrati

The World Research of Political Science Journal

Water issues have become one of the first priorities of countries, so they set out to develop future plans and water policies to preserve and develop the available water resources and rationalize their use, and to search for new water resources by using alternatives to increase their water wealth. The Nile countries are among the countries that suffer from scarcity in a desert region where surface water sources are lacking, and their location outside the heavy rain belts made them suffer from a decrease in rainfall rates, and the waters of major rivers come from outside their lands, as the …